TY  - JOUR
A1  - Uysal, Karya
A1  - Firat, Ipek Serat
A1  - Creutz, Till
A1  - Aydin, Inci Cansu
A1  - Artmann, Gerhard
A1  - Teusch, Nicole
A1  - Temiz Artmann, Aysegül
T1  - A novel in vitro wound healing assay using free-standing, ultra-thin PDMS membranes
JF  - membranes
N2  - Advances in polymer science have significantly increased polymer applications in life sciences. We report the use of free-standing, ultra-thin polydimethylsiloxane (PDMS) membranes, called CellDrum, as cell culture substrates for an in vitro wound model. Dermal fibroblast monolayers from 28- and 88-year-old donors were cultured on CellDrums. By using stainless steel balls, circular cell-free areas were created in the cell layer (wounding). Sinusoidal strain of 1 Hz, 5% strain, was applied to membranes for 30 min in 4 sessions. The gap circumference and closure rate of un-stretched samples (controls) and stretched samples were monitored over 4 days to investigate the effects of donor age and mechanical strain on wound closure. A significant decrease in gap circumference and an increase in gap closure rate were observed in trained samples from younger donors and control samples from older donors. In contrast, a significant decrease in gap closure rate and an increase in wound circumference were observed in the trained samples from older donors. Through these results, we propose the model of a cell monolayer on stretchable CellDrums as a practical tool for wound healing research. The combination of biomechanical cell loading in conjunction with analyses such as gene/protein expression seems promising beyond the scope published here.
Y1  - 2022
U6  - http://dx.doi.org/10.3390/membranes13010022
N1  - This article belongs to the Special Issue "Latest Scientific Discoveries in Polymer Membranes"
VL  - 2023
IS  - 13(1)
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Baroud, G.
A1  - Topcu, M.
A1  - Sponagel, Stefan
T1  - Soft Materials in Technology and Biology – Characteristics, Properties, and Parameter Identification
JF  - Bioengineering in Cell and Tissue Research / Artmann, Gerhard M. ; Chien, Shu (Eds.)
Y1  - 2008
SN  - 978-3-540-75408-4
SP  - 253
EP  - 315
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Sponagel, Stefan
A1  - Nguyen, Nhu Huynh
T1  - Experiment and material model for soft tissue materials
JF  - Constitutive  models for rubber VI : proceedings of the sixth European Conference on Constitutive Models for Rubber, Dresden, Germany, 7 - 10 September 2009 / eds. Gert Heinrich ...
Y1  - 2010
SN  - 978-0-415-56327-7
SP  - 465
EP  - 470
PB  - CRC Press
CY  - Boca Raton [u.a.]
ER  - 
TY  - JOUR
A1  - Doorschodt, B. M.
A1  - Schreinemachers, M. C. J. M.
A1  - Behbahani, Mehdi
A1  - Florquin, S.
A1  - Weis, J.
A1  - Staat, Manfred
A1  - Tolba, R. H.
T1  - Hypothermic machine perfusion of kidney grafts: which pressure is preferred
JF  - Annals of Biomedical Engineering. 39 (2011), H. 3
Y1  - 2011
SN  - 1573-9686
SP  - 1051
EP  - 1059
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Temiz Artmann, Aysegül
A1  - Kayatekin, Muammer B.
A1  - Uysal, N.
A1  - Resmi, H.
T1  - Does antioxidant supplementation alter the effects of acute exercise on erythrocyte aggregation, deformability and endothelium adhesion in untrained rats? Kayatekin, Muammer B.; Uysal N.; Resmi, H.; Bediz, Seref C.; Temiz Artmann, A.; Genç, S.; Tugyan, K.
JF  - International Journal for Vitamin and Nutrition Research. 75 (2005), H. 4
Y1  - 2005
SN  - 0300-9831
SP  - 243
EP  - 250
ER  - 
TY  - JOUR
A1  - Temiz Artmann, Aysegül
A1  - Resmi, Halil
A1  - Akhunlar, Hülya
A1  - Güner, Gül
T1  - In vitro effects of high glucose concentrations on membrane protein sulfhydryl oxidation, G-actin and deformability of human erythrocytes. Resmi, Halil ; Akhunlar, Hülya ; Temiz Artmann, Aysegül ; Güner, Gül
JF  - Cell biochemistry and function. 23 (2005), H. 3
Y1  - 2005
SN  - 0263-6484
SP  - 163
EP  - 168
ER  - 
TY  - JOUR
A1  - Temiz Artmann, Aysegül
A1  - Cavdar, C.
A1  - Yenicerioglu, Y.
A1  - Caliskan, S.
T1  - The effects of intravenous iron treatment on oxidant stress and erythrocyte deformability in haemodialysis patients. Cavdar, C.; Temiz, A.; Yenicerioglu, Y.; Caliskan, S.; Celik, A.; Sifil, A.; Onvural, B.; Camsari, T.
JF  - Scandinavian Journal of Urology and Nephrology. 37 (2003), H. 1
Y1  - 2003
SN  - 0036-5599
SP  - 77
EP  - 82
ER  - 
TY  - JOUR
A1  - Temiz Artmann, Aysegül
A1  - Yalcin, Ozlem
A1  - Resmi, Halil
A1  - Baskurt, Oguz K.
T1  - Can white blood cell activation be one of the major factors that affect hemorheological parameters during and after exercise?
JF  - Clinical Hemorheology and Microcirculation. 26 (2002), H. 3
Y1  - 2002
SN  - 1386-0291
N1  - = The 11th European Symposium on Clinical Hemorheology, Rouen, France, 19-22 September 2000
SP  - 189
EP  - 193
ER  - 
TY  - JOUR
A1  - Temiz Artmann, Aysegül
A1  - Baskurt, Oguz K.
A1  - Pekcetin, C.
A1  - Kandemir, F.
T1  - Leukocyte activation, oxidant stress and red blood cell properties after acute, exhausting exercise in rats. Temiz, A.; Baskurt, O. K., Pekcetin, C.; Kandemir, F.; Güre, A.
JF  - Clinical Hemorheology and Microcirculation. 22 (2000), H. 4
Y1  - 2000
SN  - 1386-0291
SP  - 253
EP  - 259
ER  - 
TY  - JOUR
A1  - Temiz Artmann, Aysegül
A1  - Yolcuoglu, B.
A1  - Onal, M. A.
A1  - Sipahi, O.
T1  - The effect of skin transplantation on tumour growth in mice. Yolcuoglu, B.; Onal, M. A.; Sipahi, O.; Temiz, A.; Pekcetin, C.; Acikgöz, O.; Kar,  H.; Güre A.
JF  - The American Journal of Surgery. 178 (1999), H. 4
Y1  - 1999
SN  - 0002-9610
SP  - 329
EP  - 330
ER  - 
TY  - JOUR
A1  - Temiz Artmann, Aysegül
A1  - Ates, H.
A1  - Üretmen, Ö.
A1  - Andac, K.
T1  - Erythrocyte deformability in high-tension and normal tension glaucoma. Ates, H.; Üretmen, Ö.; Temiz, A.; Andac, K.
JF  - International Ophthalmology. 22 (1998), H. 1
Y1  - 1998
SN  - 0165-5701
SP  - 7
EP  - 12
ER  - 
TY  - JOUR
A1  - Temiz Artmann, Aysegül
A1  - Baskurt, O. K.
A1  - Meiselman, H. J.
T1  - Effect of superoxide anions on red blood cell rheologic properties. Baskurt, O. K.; Temiz, A.; Meiselman, H. J.
JF  - Free Radical Biology and Medicine. 24 (1998), H. 1
Y1  - 1998
SN  - 0891-5849
SP  - 102
EP  - 110
ER  - 
TY  - JOUR
A1  - Temiz Artmann, Aysegül
A1  - Baskurt, O. K.
A1  - Meiselman, H. J.
T1  - Red blood cell aggregation in experimental sepsis . Baskurt, O. K.; Temiz, A.; Meiselman, H. J.
JF  - Journal of Laboratory and Clinical Medicine. 130 (1997), H. 2
Y1  - 1997
SN  - 0022-2143
SP  - 183
EP  - 190
ER  - 
TY  - JOUR
A1  - Temiz Artmann, Aysegül
A1  - Baskurt, O. K.
A1  - Edremitlioglu, M.
T1  - Effect of erythrocyte deformability on myocardial hematocrit gradient. Baskurt, O.K.; Edremitlioglu, M.; Temiz, A.
JF  - American Journal of Physiology: Heart and Circulatory Physiology. 268 (1995), H. 1
Y1  - 1995
SN  - 0363-6135
SP  - 260
EP  - 264
ER  - 
TY  - JOUR
A1  - Temiz Artmann, Aysegül
A1  - Baskurt, O. K.
A1  - Edremitlioglu, M.
T1  - In vitro effects of in vivo activated leukocytes on red blood cell filterability and lipid peroxidation. Baskurt, O.K.; Edremitlioglu, M.; Temiz, A.
JF  - Clinical Hemorheology. 14 (1994), H. 4
Y1  - 1994
SP  - 591
EP  - 596
ER  - 
TY  - JOUR
A1  - Temiz Artmann, Aysegül
A1  - Akhisaroglu, M.
A1  - Sercan, Z.
A1  - Kayatekin, B. M.
T1  - Adhesion of Erythrocytes to Endothelial Cells After Acute Exercise: Differences in Red Blood Cells from Juvenile and Adult Rats. Temiz Artmann, A.; Akhisaroglu, M.; Sercan, Z.; Kayatekin, BM.; Yorukoglu, K.; Kirkali, G.
JF  - Physiological  Research (2005)
Y1  - 2005
SN  - 0862-8408
N1  - pre-press article
ER  - 
TY  - JOUR
A1  - Temiz Artmann, Aysegül
A1  - Kayser, Peter
T1  - Why is Sepsis an Ongoing Clinical Challenge? Lipopolysaccharide Effects on Red Blood Cell Volume / Temiz, Aysegül ;  Kayser, Peter
JF  - Bioengineering in Cell and Tissue Research / Artmann, Gerhard M. ; Chien, Shu (Eds.)
Y1  - 2008
SN  - 978-3-540-75408-4
SP  - 497
EP  - 508
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Temiz Artmann, Aysegül
A1  - Saklamaz, Ali
A1  - Comlekci, Abdurrahman
A1  - Caliskan, Sezer
T1  - The beneficial effects of lipid-lowering drugs beyond lipid-lowering effects: A comparative study with pravastatin, atorvastatin, and fenofibrate in patients with type IIa and type IIb hyperlipidemia / Saklamaz, Ali ; Comlekci, Abdurrahman ; Temiz, Aysegu
JF  - Metabolism. 54 (2005), H. 5
Y1  - 2005
SN  - 0026-0495
SP  - 677
EP  - 681
ER  - 
TY  - JOUR
A1  - Erbayraktar, Zubeyde
A1  - Yilmaz, Osman
A1  - Temiz Artmann, Aysegül
A1  - Cehreli, Ruksan
A1  - Coker, Canan
T1  - Effects of Selenium Supplementation on Antioxidant Defense and Glucose Homeostasis in Experimental Diabetes Mellitus
JF  - Biological Trace Element Research
Y1  - 2007
SN  - 1559-0720
VL  - 118
IS  - 3
SP  - 217
EP  - 226
ER  - 
TY  - JOUR
A1  - Cehreli, Ruksan
A1  - Akpinar, Hale
A1  - Temiz Artmann, Aysegül
A1  - Sagol, Ozgul
T1  - Effects of Glutamine and Omega-3 Fatty Acids on Erythrocyte Deformability and Oxidative Damage in Rat Model of Enterocolitis
JF  - Gastroenterology Research
Y1  - 2015
U6  - http://dx.doi.org/10.14740/gr683w
SN  - 1918-2813
VL  - 8
IS  - 5
SP  - 265
EP  - 273
ER  -