TY  - JOUR
A1  - Staat, Manfred
T1  - Limit and shakedown analysis under uncertainty
JF  - International journal of computational methods : IJCM
Y1  - 2013
SN  - 0219-8762
SP  - Publ. online
PB  - World Scientific Publishing
CY  - Singapore
ER  - 
TY  - CHAP
A1  - Frotscher, Ralf
A1  - Staat, Manfred
ED  - Artmann, Gerhard
ED  - Temiz Artmann, Aysegül
ED  - Zhubanova, Azhar A.
ED  - Digel, Ilya
T1  - Towards Patient-Specific Computational Modeling of hiPS-Derived Cardiomyocyte Function and Drug Action
T2  - Biological, Physical and Technical Basics of Cell Engineering
N2  - Human-induced pluripotent stem cell-derived cardiomyocytes (hiPS-CM) today are widely used for the investigation of normal electromechanical cardiac function, of cardiac medication and of mutations. Computational models are thus established that simulate the behavior of this kind of cells. This section first motivates the modeling of hiPS-CM and then presents and discusses several modeling approaches of microscopic and macroscopic constituents of human-induced pluripotent stem cell-derived and mature human cardiac tissue. The focus is led on the mapping of the computational results one can achieve with these models onto mature human cardiomyocyte models, the latter being the real matter of interest. Model adaptivity is the key feature that is discussed because it opens the way for modeling various biological effects like biological variability, medication, mutation and phenotypical expression. We compare the computational with experimental results with respect to normal cardiac function and with respect to inotropic and chronotropic drug effects. The section closes with a discussion on the status quo of the specificity of computational models and on what challenges have to be solved to reach patient-specificity.
Y1  - 2018
SN  - 978-981-10-7904-7
U6  - https://doi.org/10.1007/978-981-10-7904-7_10
SP  - 233
EP  - 250
PB  - Springer
CY  - Singapore
ER  - 
TY  - CHAP
A1  - Tran, Thanh Ngoc
A1  - Staat, Manfred
ED  - Eberhardsteiner, J.
T1  - A primal-dual shakedown analysis of 3D structures using the face-based smoothed finite element method
T2  - Proceedings European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012)
Y1  - 2012
N1  - 6th European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012) Vienna, Austria, September 10-14, 2012
ER  - 
TY  - CHAP
A1  - Frotscher, Ralf
A1  - Raatschen, Hans-Jürgen
A1  - Staat, Manfred
ED  - Holzapfel, Gerhard A.
T1  - Effectiveness of the edge-based smoothed finite element method applied to soft biological tissues
T2  - ESMC-2012 - 8th European Solid Mechanics Conference, Graz, Austria, July 9-13, 2012
Y1  - 2012
SN  - 978-3-85125-223-1
PB  - Verlag d. Technischen Universität Graz
CY  - Graz
ER  - 
TY  - CHAP
A1  - Tran, Ngoc Trinh
A1  - Tran, Thanh Ngoc
A1  - Matthies, Hermann G.
A1  - Stavroulakis, Georgios Eleftherios
A1  - Staat, Manfred
T1  - FEM Shakedown of uncertain structures by chance constrained programming
T2  - PAMM Proceedings in Applied Mathematics and Mechanics
Y1  - 2016
U6  - https://doi.org/10.1002/pamm.201610346
SN  - 1617-7061
N1  - Special Issue:
Joint 87th Annual Meeting of the International Association of Applied Mathematics and Mechanics (GAMM) and Deutsche Mathematiker-Vereinigung
VL  - 16
IS  - 1
SP  - 715
EP  - 716
ER  - 
TY  - JOUR
A1  - Grottke, O.
A1  - Braunschweig, T.
A1  - Philippen, B.
A1  - Gatzweiler, Karl-Heinz
A1  - Gronloh, N.
A1  - Staat, Manfred
A1  - Rossaint, R.
A1  - Tolba, R.
T1  - A New Model for Blunt Liver Injuries in the Swine
JF  - European Surgical Research. 44 (2010), H. 2
Y1  - 2010
SN  - 1421-9921
SP  - 65
EP  - 73
ER  - 
TY  - JOUR
A1  - Jung, Alexander
A1  - Staat, Manfred
T1  - Modeling and simulation of human induced pluripotent stem cell-derived cardiac tissue
JF  - GAMM - Mitteilungen der Gesellschaft für Angewandte Mathematik und Mechanik
Y1  - 2019
U6  - https://doi.org/10.1002/gamm.201900002
SN  - 1522-2608
VL  - 42
IS  - 4
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - CHAP
A1  - Frotscher, Ralf
A1  - Staat, Manfred
T1  - An electromechanical model for cardiac tissue constructs
T2  - Conference proceedings of the YIC GACM 2015 : 3rd ECCOMAS Young Investigators Conference and 6th GACM Colloquium on Computational Mechanics , Aachen, 20.07.2015 - 23.07.2015  / ed.: Stefanie Elgeti ; Jaan-Willem Simon
Y1  - 2015
SP  - 1
EP  - 4
PB  - RWTH Aachen University
CY  - Aachen
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Fiorini, G. L.
A1  - Lensa, W. von
A1  - Burgazzi, L.
T1  - Reliability Methods for Passive Safety Functions
JF  - Proceedings of the SMiRT 14 Post Conference Seminar No 18 on Passive Safety Features in Nuclear Installations
Y1  - 1997
CY  - Pisa
ER  - 
TY  - JOUR
A1  - Jayaraman, Chandrasekaran
A1  - Mummidisetty, Chaitanya Krishna
A1  - Loesch, Alexandra
A1  - Kaur, Sandi
A1  - Hoppe-Ludwig, Shenan
A1  - Staat, Manfred
A1  - Jayaraman, Arun
T1  - Postural and metabolic benefits of using a forearm support walker in older adults with impairments
JF  - Archives of Physical Medicine and Rehabilitation
Y1  - 2019
U6  - https://doi.org/10.1016/j.apmr.2018.10.001
SN  - 0003-9993
VL  - Volume 100
IS  - Issue 4
SP  - 638
EP  - 647
PB  - Elsevier
CY  - Amsterdam
ER  -