TY  - JOUR
A1  - Frotscher, Ralf
A1  - Koch, Jan-Peter
A1  - Staat, Manfred
T1  - Computational investigation of drug action on human-induced stem cell derived cardiomyocytes
JF  - Journal of biomechanical engineering
Y1  - 2015
U6  - https://doi.org/10.1115/1.4030173
SN  - 1528-8951 (E-Journal); 0148-0731 (Print)
VL  - Vol. 137
IS  - iss. 7
SP  - 071002-1
EP  - 071002-7
PB  - ASME
CY  - New York
ER  - 
TY  - CHAP
A1  - Frotscher, Ralf
A1  - Goßmann, Matthias
A1  - Raatschen, Hans-Jürgen
A1  - Temiz Artmann, Aysegül
A1  - Staat, Manfred
T1  - Simulation of cardiac cell-seeded membranes using the edge-based smoothed FEM
T2  - Shell and membrane theories in mechanics and biology. (Advanced structured materials ; 45)
N2  - We present an electromechanically coupled Finite Element model for cardiac tissue. It bases on the mechanical model for cardiac tissue of Hunter et al. that we couple to the McAllister-Noble-Tsien electrophysiological model of purkinje fibre cells. The corresponding system of ordinary differential equations is implemented on the level of the constitutive equations in a geometrically and physically nonlinear version of the so-called edge-based smoothed FEM for plates. Mechanical material parameters are determined from our own pressure-deflection experimental setup. The main purpose of the model is to further examine the experimental results not only on mechanical but also on electrophysiological level down to ion channel gates. Moreover, we present first drug treatment simulations and validate the model with respect to the experiments.
Y1  - 2015
SN  - 978-3-319-02534-6 ; 978-3-319-02535-3
SP  - 187
EP  - 212
PB  - Springer
CY  - Heidelberg
ER  - 
TY  - CHAP
A1  - Frotscher, Ralf
A1  - Duong, Minh Tuan
A1  - Staat, Manfred
T1  - Simulating beating cardiomyocytes with electromechanical coupling
T2  - II. International Conference on Biomedical Technology : 28-30 October 2015 Hannover, Germany / T. Lenarz, P. Wriggers (Eds.)
Y1  - 2015
SP  - 1
EP  - 2
ER  - 
TY  - JOUR
A1  - Duong, Minh Tuan
A1  - Nguyen, Nhu Huynh
A1  - Tran, Thanh Ngoc
A1  - Tolba, R. H.
A1  - Staat, Manfred
T1  - Influence of refrigerated storage on tensile mechanical properties of porcine liver and spleen
JF  - International biomechanics
Y1  - 2015
U6  - https://doi.org/10.1080/23335432.2015.1049295
SN  - 2333-5432
VL  - Vol. 2
IS  - Iss. 1
SP  - 79
EP  - 88
PB  - Taylor & Francis
CY  - London
ER  - 
TY  - JOUR
A1  - Duong, Minh Tuan
A1  - Nguyen, Nhu Huynh
A1  - Staat, Manfred
T1  - Physical response of hyperelastic models for composite materials and soft tissues
JF  - Asia pacific journal on computational engineering
Y1  - 2015
U6  - https://doi.org/10.1186/s40540-015-0015-x
SN  - 2196-1166
VL  - 2
IS  - 3 (December 2015)
SP  - 1
EP  - 18
ER  - 
TY  - CHAP
A1  - Duong, Minh Tuan
A1  - Nguyen, N. H.
A1  - Staat, Manfred
T1  - Modeling and simulation of a growing mass by the Smoothed Finite Element Method (SFEM)
T2  - Conference proceedings of the YIC GACM 2015 : 3rd ECCOMAS Young Investigators Conference and 6th GACM Colloquium on Computational Mechanics , Aachen, Germany, 20.07.2015 - 23.07.2015  / ed.: Stefanie Elgeti ; Jaan-Willem Simon
Y1  - 2015
SP  - 1
EP  - 4
PB  - RWTH Aachen University
CY  - Aachen
ER  - 
TY  - THES
A1  - Duong, Minh Tuan
T1  - Hyperelastic modeling and soft-tissue growth integrated with the smoothed finite element method - SFEM
Y1  - 2015
N1  - Aachen, Techn. Hochsch., Diss., 2014
PB  - RWTH Aachen University
ER  - 
TY  - CHAP
A1  - Digel, Ilya
A1  - Sadykov, R.
A1  - Temiz Artmann, Aysegül
A1  - Artmann, Gerhard
T1  - Changes in intestinal microflora in rats induced by oral exposure to low lead (II) concentrations
T2  - Lead Exposure and Poisoning: Clinical Symptoms, Medical Management and Preventive Strategies
Y1  - 2015
SN  - 9781634826990
SP  - 75
EP  - 99
PB  - Nova Science Publ.
ER  - 
TY  - JOUR
A1  - Cehreli, Ruksan
A1  - Akpinar, Hale
A1  - Temiz Artmann, Aysegül
A1  - Sagol, Ozgul
T1  - Effects of Glutamine and Omega-3 Fatty Acids on Erythrocyte Deformability and Oxidative Damage in Rat Model of Enterocolitis
JF  - Gastroenterology Research
Y1  - 2015
U6  - https://doi.org/10.14740/gr683w
SN  - 1918-2813
VL  - 8
IS  - 5
SP  - 265
EP  - 273
ER  - 
TY  - CHAP
A1  - Bhattarai, Aroj
A1  - Frotscher, Ralf
A1  - Staat, Manfred
T1  - Biomechanical study of the female pelvic floor dysfunction using the finite element method
T2  - Conference proceedings of the YIC GACM 2015 : 3rd ECCOMAS Young Investigators Conference and 6th GACM Colloquium on Computational Mechanics , Aachen , Germany, 20.07.2015 - 23.07.2015  / ed.: Stefanie Elgeti ; Jaan-Willem Simon
Y1  - 2015
SP  - 1
EP  - 4
PB  - RWTH Aachen University
CY  - Aachen
ER  -