TY - RPRT A1 - Artmann, Gerhard A1 - Bäumler, H. T1 - Pharmamikrocontainer mit designgesteuerter Permeabilität als Transporter für ausgewählte Pharmaka. Ein Gemeinschaftsprojekt im Forschungsschwerpunkt "Celluar Engineering" [Laufzeit: 01.09.2000 - 28.02.2002] Y1 - 2002 PB - FH Aachen CY - Jülich ER - TY - RPRT A1 - Artmann, Gerhard T1 - Plant mutant scanner : Hochdurchsatzscanner zur Charakterisierung von Pflanzenmutanten. Abschlussbericht ; FHprofUnd ; PhytoScan ; Laufzeit des Vorhabens: 01.07.2008 - 30.06.2011 Y1 - 2011 U6 - http://dx.doi.org/10.2314/GBV:747569150 N1 - Förderkennzeichen BMBF 1736X08 PB - Technische Informationsbibliothek u. Universitätsbibliothek CY - Aachen ER - TY - RPRT A1 - Artmann, Gerhard T1 - Escherichia Coli Infektion und Zellschädigung - Wie perfekt wirken Antibiotika? : Abschlussbericht zum Projekt 1703701 Y1 - 2004 U6 - http://dx.doi.org/10.2314/GBV:482527137 PB - Technische Informationsbibliothek u. Universitätsbibliothek CY - Jülich ER - TY - RPRT A1 - Artmann, Gerhard T1 - FhprofUnd EasyBioforce Abschlussbericht : Miniaturisierte, integrierte und automatisierte Screening Plattform eines 36-Well-Hochdurchsatz-Testsystems zur funktionellen Kraftmessung an Zell- und Gewebeschichten für die Arzneimittelforschung : Laufzeit des Vorhabens: 01.03.2007 - 31.12.2010 Y1 - 2011 U6 - http://dx.doi.org/10.2314/GBV:782964621 N1 - Förderkennzeichen BMBF 1760X07 PB - Technische Informationsbibliothek u. Universitätsbibliothek CY - Aachen ER - TY - RPRT A1 - Artmann, Gerhard T1 - HPBioforce: Integrierte und automatisierte Screening Plattform eines 96-Well-Hochdurchsatz-Testsystems zur funktionellen Kraftmessung an einige um dicken Zell- und Gewebeschichten für die Arzneimittelforschung : gemeinsamer Abschlussbericht der FH Aachen, Hitec Zang GmbH, IKFE Mainz, IKFE Berlin und der Dr. Gerhard Schmidt GmbH zum InnoNet-Projekt ... ; Programm "Förderung von innovativen Netzwerken" (InnoNet) des Bundesministerium für Wirtschaft und Technologie (BMWi) ; Laufzeit: 01.05.2007 bis 31.12.2010 Y1 - 2011 U6 - http://dx.doi.org/10.2314/GBV:68757076X N1 - Förderkennzeichen BMWi 16IN0536. - Verbund-Nr. 01056220 PB - Technische Informationsbibliothek u. Universitätsbibliothek CY - Aachen [u.a.] ER - TY - JOUR A1 - Neumaier, Felix A1 - Kotliar, Konstantin A1 - Haeren, Roel Hubert Louis A1 - Temel, Yasin A1 - Lüke, Jan Niklas A1 - Seyam, Osama A1 - Lindauer, Ute A1 - Clusmann, Hans A1 - Hescheler, Jürgen A1 - Schubert, Gerrit Alexander A1 - Schneider, Toni A1 - Albanna, Walid T1 - Retinal Vessel Responses to Flicker Stimulation Are Impaired in Ca v 2.3-Deficient Mice—An in- vivo Evaluation Using Retinal Vessel Analysis (RVA) JF - Frontiers in Neurology Y1 - 2021 U6 - http://dx.doi.org/10.3389/fneur.2021.659890 VL - 12 SP - 1 EP - 11 PB - Frontiers ER - TY - CHAP A1 - Akimbekov, Nuraly S. A1 - Digel, Ilya A1 - Razzaque, Mohammed S. T1 - Role of vitamins in maintaining structure and function of intestinal microbiome T2 - Comprehensive Gut Microbiota N2 - The recent advances in microbiology have shed light on understanding the role of vitamins beyond the nutritional range. Vitamins are critical in contributing to healthy biodiversity and maintaining the proper function of gut microbiota. The sharing of vitamins among bacterial populations promotes stability in community composition and diversity; however, this balance becomes disturbed in various pathologies. Here, we overview and analyze the ability of different vitamins to selectively and specifically induce changes in the intestinal microbial community. Some schemes and regularities become visible, which may provide new insights and avenues for therapeutic management and functional optimization of the gut microbiota. KW - Vitamin A KW - Vitamin B KW - Thiamine KW - Riboflavin KW - Niacin Y1 - 2022 SN - 978-0-12-822036-8 U6 - http://dx.doi.org/10.1016/B978-0-12-819265-8.00043-7 SP - 320 EP - 334 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Hackl, Michael A1 - Nacov, Julia A1 - Kammerlohr, Sandra A1 - Staat, Manfred A1 - Buess, Eduard A1 - Leschinger, Tim A1 - Müller, Lars P. A1 - Wegmann, Kilian T1 - Intratendinous Strain Variations of the Supraspinatus Tendon Depending on Repair Technique: A Biomechanical Analysis Regarding the Cause of Medial Cuff Failure JF - The American Journal of Sports Medicine Y1 - 2021 U6 - http://dx.doi.org/10.1177/03635465211006138 SN - 1552-3365 SN - 0363-5465 VL - 49 IS - 7 SP - 1847 EP - 1853 PB - Sage CY - London ER - TY - JOUR A1 - Waldvogel, Janice A1 - Ritzmann, Ramona A1 - Freyler, Kathrin A1 - Helm, Michael A1 - Monti, Elena A1 - Albracht, Kirsten A1 - Stäudle, Benjamin A1 - Gollhofer, Albert A1 - Narici, Marco T1 - The Anticipation of Gravity in Human Ballistic Movement JF - Frontiers in Physiology N2 - Stretch-shortening type actions are characterized by lengthening of the pre-activated muscle-tendon unit (MTU) in the eccentric phase immediately followed by muscle shortening. Under 1 g, pre-activity before and muscle activity after ground contact, scale muscle stiffness, which is crucial for the recoil properties of the MTU in the subsequent push-off. This study aimed to examine the neuro-mechanical coupling of the stretch-shortening cycle in response to gravity levels ranging from 0.1 to 2 g. During parabolic flights, 17 subjects performed drop jumps while electromyography (EMG) of the lower limb muscles was combined with ultrasound images of the gastrocnemius medialis, 2D kinematics and kinetics to depict changes in energy management and performance. Neuro-mechanical coupling in 1 g was characterized by high magnitudes of pre-activity and eccentric muscle activity allowing an isometric muscle behavior during ground contact. EMG during pre-activity and the concentric phase systematically increased from 0.1 to 1 g. Below 1 g the EMG in the eccentric phase was diminished, leading to muscle lengthening and reduced MTU stretches. Kinetic energy at take-off and performance were decreased compared to 1 g. Above 1 g, reduced EMG in the eccentric phase was accompanied by large MTU and muscle stretch, increased joint flexion amplitudes, energy loss and reduced performance. The energy outcome function established by linear mixed model reveals that the central nervous system regulates the extensor muscles phase- and load-specifically. In conclusion, neuro-mechanical coupling appears to be optimized in 1 g. Below 1 g, the energy outcome is compromised by reduced muscle stiffness. Above 1 g, loading progressively induces muscle lengthening, thus facilitating energy dissipation. Y1 - 2021 U6 - http://dx.doi.org/10.3389/fphys.2021.614060 SN - 1664-042X PB - Frontiers CY - Lausanne ER - TY - THES A1 - Bayer, Robin T1 - Development of a novel in-vitro vascular model for determination of physiological and pathophysiological mechanobiology Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:38-362212 N1 - Dissertation, Universität zu Köln, 2021 PB - Universität zu Köln CY - Köln ER -