TY  - CHAP
A1  - Knott, Thomas C.
A1  - Sofronia, Raluca E.
A1  - Gerressen, Marcus
A1  - Law, Yuen
A1  - Davidescu, Arjana
A1  - Savii, George G.
A1  - Gatzweiler, Karl-Heinz
A1  - Staat, Manfred
A1  - Kuhlen, Torsten W.
T1  - Preliminary bone sawing model for a virtual reality-based training simulator of bilateral sagittal split osteotomy
T2  - Biomedical simulation : 6th International Symposium, ISBMS 2014, Strasbourg, France, October 16-17, 2014 : proceedings (Lecture notes in computer science : vol. 8789)
N2  - Successful bone sawing requires a high level of skill and experience, which could be gained by the use of Virtual Reality-based simulators. A key aspect of these medical simulators is realistic force feedback. The aim of this paper is to model the bone sawing process in order to develop a valid training simulator for the bilateral sagittal split osteotomy, the most often applied corrective surgery in case of a malposition of the mandible. Bone samples from a human cadaveric mandible were tested using a designed experimental system. Image processing and statistical analysis were used for the selection of four models for the bone sawing process. The results revealed a polynomial dependency between the material removal rate and the applied force. Differences between the three segments of the osteotomy line and between the cortical and cancellous bone were highlighted.
KW  - Bone sawing
KW  - virtual reality
KW  - training simulator
Y1  - 2014
SN  - 978-3-319-12057-7 (Online)
SN  - 978-3-319-12056-0 (Print)
U6  - https://doi.org/10.1007/978-3-319-12057-7_1
SP  - 1
EP  - 10
PB  - Springer
CY  - Cham
ER  - 
TY  - CHAP
A1  - Frotscher, Ralf
A1  - Goßmann, Matthias
A1  - Raatschen, Hans-Jürgen
A1  - Temiz Artmann, Aysegül
A1  - Staat, Manfred
T1  - Simulation of cardiac cell-seeded membranes using the edge-based smoothed FEM
T2  - Shell and membrane theories in mechanics and biology. (Advanced structured materials ; 45)
N2  - We present an electromechanically coupled Finite Element model for cardiac tissue. It bases on the mechanical model for cardiac tissue of Hunter et al. that we couple to the McAllister-Noble-Tsien electrophysiological model of purkinje fibre cells. The corresponding system of ordinary differential equations is implemented on the level of the constitutive equations in a geometrically and physically nonlinear version of the so-called edge-based smoothed FEM for plates. Mechanical material parameters are determined from our own pressure-deflection experimental setup. The main purpose of the model is to further examine the experimental results not only on mechanical but also on electrophysiological level down to ion channel gates. Moreover, we present first drug treatment simulations and validate the model with respect to the experiments.
Y1  - 2015
SN  - 978-3-319-02534-6 ; 978-3-319-02535-3
SP  - 187
EP  - 212
PB  - Springer
CY  - Heidelberg
ER  - 
TY  - JOUR
A1  - Stadler, Alexander Maximilian
A1  - Garvey, Christopher J.
A1  - Embs, Jan Peter
A1  - Koza, Michael Marek
A1  - Unruh, Tobias
A1  - Artmann, Gerhard
A1  - Zaccai, Guiseppe
T1  - Picosecond dynamics in haemoglobin from different species: A quasielastic neutron scattering study
JF  - Biochimica et biophysica acta (BBA): General Subjects
Y1  - 2014
U6  - https://doi.org/10.1016/j.bbagen.2014.06.007
SN  - 1872-8006 (E-Journal); 0304-4165 (Print)
VL  - 1840
IS  - 10
SP  - 2989
EP  - 2999
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - CHAP
A1  - Dachwald, Bernd
A1  - Feldmann, Marco
A1  - Espe, Clemens
A1  - Plescher, Engelbert
A1  - Konstantinidis, K.
A1  - Forstner, R.
T1  - Enceladus explorer - A maneuverable subsurface probe for autonomous navigation through deep ice
T2  - 63rd International Astronautical Congress 2012, IAC 2012; Naples; Italy; 1 October 2012 through 5 October 2012. (Proceedings of the International Astronautical Congress, IAC ; 3)
Y1  - 2012
SN  - 978-1-62276-979-7
SP  - 1756
EP  - 1766
PB  - Curran
CY  - Red Hook, NY
ER  - 
TY  - CHAP
A1  - Konstantinidis, K.
A1  - Dachwald, Bernd
A1  - Ohndorf, A.
A1  - Dykta, P.
A1  - Voigt, K.
A1  - Förstner, R.
T1  - Enceladus explorer (ENEX): A lander mission to probe subglacial water pockets on Saturn's moon enceladus for life
T2  - 64th International Astronautical Congress 2013 (IAC 2013) : Beijing, China, 23 - 27 September 2013. (Proceedings of the International Astronautical Congress, IAC ; 2)
Y1  - 2013
SN  - 978-1-62993-909-4
SP  - 1340
EP  - 1350
PB  - Curran
CY  - Red Hook, NY
ER  - 
TY  - JOUR
A1  - Frotscher, Ralf
A1  - Staat, Manfred
T1  - Stresses produced by different textile mesh implants in a tissue equivalent
JF  - BioNanoMaterials
N2  - Two single-incision mini-slings used for treating urinary incontinence in women are compared with respect to the stresses they produce in their surrounding tissue. In an earlier paper we experimentally observed that these implants produce considerably different stress distributions in a muscle tissue equivalent. Here we perform 2D finite element analyses to compare the shear stresses and normal stresses in the tissue equivalent for the two meshes and to investigate their failure behavior. The results clearly show that the Gynecare TVT fails for increasing loads in a zipper-like manner because it gradually debonds from the surrounding tissue. Contrary to that, the tissue at the ends of the DynaMesh-SIS direct may rupture but only at higher loads. The simulation results are in good agreement with the experimental observations thus the computational model helps to interpret the experimental results and provides a tool for qualitative evaluation of mesh implants.
Y1  - 2014
U6  - https://doi.org/10.1515/bnm-2014-0003
SN  - 2191-4672 (E-Journal); 2193-066X (E-Journal); 0011-8656 (Print); 1616-0177 (Print); 2193-0651 (Print)
VL  - 15
IS  - 1-2
SP  - 25
EP  - 30
PB  - De Gruyter
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Ciobanu, Octavian
A1  - Staat, Manfred
A1  - Rahimi, Alireza
T1  - The use of open source software in biomechanical finite element analysis
JF  - Buletinul Institutului Politehnic din Iaşi / Universitatea Tehnică Gh. Asachi, Iaşi Secţia 5, Construcţii de maşini = Machine construction = Bulletin of the Polytechnic Institute of Jassy = Izvestija Jasskogo Politechničeskogo Instituta
Y1  - 2008
SN  - 1011-2855
VL  - 54
IS  - 7/8
SP  - 213
EP  - 220
ER  - 
TY  - JOUR
A1  - Mansurov, Zulkhair A.
A1  - Jandosov, J. M.
A1  - Kerimkulova, A. R.
A1  - Azat, S.
A1  - Zhubanova, Azhar Achmet
A1  - Digel, Ilya
A1  - Savistkaya, I. S.
A1  - Akimbekov, Nuraly S.
A1  - Kistaubaeva, A. S.
T1  - Nanostructured carbon materials for biomedical use
JF  - Eurasian chemico-technological journal : quarterly journal of the International Higher Education Academy of Sciences
N2  - One of the priority trends of carbon nanotechnology is creation of nanocomposite systems. Such carbon nanostructured composites were produced using - raw materials based on the products of agricultural waste, such as grape stones, apricot stones, rice husk. These products have a - wide spectrum of application and can be obtained in large quantities. The Institute of Combustion Problems has carried out the work on synthesis of the nanostructured carbon sorbents for multiple applications including the field of biomedicine. The article presents the data on the synthesis and physico-chemical properties of carbonaceous sorbents using physicochemical methods of investigation: separation and purification of biomolecules; isolation of phytohormone - fusicoccin; adsorbent INGO-1 in the form of an adsorption column for blood detoxification, oral (entero) sorbent - INGO-2; the study of efferent and probiotic properties and sorption activity in regard to the lipopolysaccharide (LPS), new biocomposites - based on carbonized rice husk (CRH) and cellular microorganisms; the use of CRH in wound treatment. A new material for blood detoxication (INGO-1) has been obtained. Adsorption of p-cresyl sulfate and indoxyl sulfate has shown that active carbon adsorbent can remove clinically significant level of p-cresyl sulfate and indoxyl sulfate from human plasma. Enterosorbent INGO-2 possesses high adsorption activity in relation to Gram-negative bacteria and their endotoxins. INGO-2 slows down the growth of conditionally pathogenic microorganisms, without having a negative effect on bifido and lactobacteria. The use of enterosorbent INGO-2 for sorption therapy may provide a solution to a complex problem - detoxication of the digestive tract and normalization of the intestinal micro ecology. The immobilized probiotic called "Riso-lact" was registered at the Ministry of Health of the Republic of Kazakhstan as a biologically active food additive. The developed technology is patented and provides production of the medicine in the form of freeze-dried biomass immobilized in vials.
Y1  - 2014
U6  - https://doi.org/10.18321/ectj224
SN  - 1562-3920
VL  - 15 (2013)
IS  - 3
SP  - 209
EP  - 217
PB  - Institute of Combustion Problems
CY  - Almaty
ER  - 
TY  - CHAP
A1  - Tran, Ngoc Trinh
A1  - Staat, Manfred
A1  - Stavroulakis, G. E.
ED  - Onate, E.
T1  - A multicriteria method for truss optimization
T2  - 11th World Congress on Computational Mechanics (WCCM XI) ; 5th European Conference on Computational Mechanics (ECCM V) ; 6th European Conference on Computational Fluid Dynamics (ECFD VI) ; July 20-25, 2014, Barcelona
Y1  - 2014
SP  - 1
EP  - 12
ER  - 
TY  - CHAP
A1  - Duong, Minh Tuan
A1  - Staat, Manfred
ED  - Onate, E.
T1  - A face-based smoothed finite element method for hyperelastic models and tissue growth
T2  - 11th World Congress on Computational Mechanics (WCCM XI) ; 5th European Conference on Computational Mechanics (ECCM V) ; 6th European Conference on Computational Fluid Dynamics (ECFD VI) ; July 20-25, 2014, Barcelona
Y1  - 2014
SP  - 1
EP  - 12
ER  -