TY  - JOUR
A1  - Ziemons, Karl
A1  - Heinrichs, U.
A1  - Streun, M.
A1  - Pietrzyk, U.
T1  - Validation of GEANT3 simulation studies with a dual-head PMT ClearPET™ prototype
JF  - 2003 IEEE Nuclear Science Symposium Conference Record, Vol. 5
N2  - The ClearPET™ project is proposed by working groups of the Crystal Clear Collaboration (CCC) to develop a 2nd generation high performance small animal positron emission tomograph (PET). High sensitivity and high spatial resolution is foreseen for the ClearPET™ camera by using a phoswich arrangement combining mixed lutetium yttrium aluminum perovskite (LuYAP:Ce) and lutetium oxyorthosilicate (LSO) scintillating crystals. Design optimizations for the first photomultiplier tube (PMT) based ClearPET camera are done with a Monte-Carlo simulation package implemented on GEANT3 (CERN, Geneva, Switzerland). A dual-head prototype has been built to test the frontend electronics and was used to validate the implementation of the GEANT3 simulation tool. Multiple simulations were performed following the experimental protocols to measure the intrinsic resolution and the sensitivity profile in axial and radial direction. Including a mean energy resolution of about 27.0% the simulated intrinsic resolution is about (1.41±0.11)mm compared to the measured of (1.48±0.06)mm. The simulated sensitivity profiles show a mean square deviation of 12.6% in axial direction and 3.6% in radial direction. Satisfactorily these results are representative for all designs and confirm the scanner geometry.
Y1  - 2004
SN  - 1082-3654
SP  - 3053
EP  - 3056
ER  - 
TY  - JOUR
A1  - Ziemons, Karl
A1  - Auffray, E.
A1  - Barbier, R.
A1  - Brandenburg, G.
T1  - The ClearPET TM LSO/LuYAP phoswich scanner: a high performance small animal PET system
JF  - 2003 IEEE Nuclear Science Symposium Conference Record, Vol. 3
N2  - A 2nd generation high performance small animal PET scanner, called ClearPET™, has been designed and a first prototype is built by working groups of the Crystal Clear Collaboration (CCC). In order to achieve high sensitivity and maintain good uniform spatial resolution over the field of view in high resolution PET systems, it is necessary to extract the depth of interaction (DOI) information and correct for spatial degradation. The design of the first ClearPET™ Demonstrator based on the use of the multi-anode photomultiplier tube (Hamamatsu R7600-M64) and a LSO/LuYAP phoswich matrix. The two crystal layers of 8*8 crystals (2*2*10 mm3) are stacked on each other and mounted without light guide as one to one on the PMT. A unit of four PMTs arranged in-line represents one of 20 sectors of the ring design. The opening diameter of the crystal ring is 137 mm, the axial detector length is 110 mm. The PMT pulses are digitized by free-running ADCs and digital data processing determines the gamma energy, the phoswich layer and even the pulse arrival time. Single gamma interactions are recorded and coincidences are found by software. The gantry allows rotation of the detector modules around the field of view. The measurements have been done using the first LSO/LuYAP detector cassettes.
Y1  - 2004
SN  - 1082-3654
SP  - 1728
EP  - 1732
ER  - 
TY  - JOUR
A1  - Ziemons, Karl
A1  - Achten, R.
A1  - Auffray, E.
A1  - Müller-Veggian, Mattea
T1  - The ClearPET™ neuro scanner: a dedicated LSO/LuYAP phoswich small animal PET scanner
JF  - 2004 IEEE Nuclear Science Symposium conference record : Nuclear Science Symposium, Medical Imaging Conference ; 16 - 22 October 2004, Rome, Italy ; [including the Symposium on Nuclear Power System (SNPS), 14th Room Temperature Semiconductor X- and Gamma-Ray Detectors Workshop and special focus workshops] / NPSS, Nuclear & Plasma Sciences Society. Guest ed.: J. Anthony Seibert
Y1  - 2004
SN  - 1082-3654
N1  - Nuclear Science Symposium Conference Record, 2004 IEEE
SP  - 2430
EP  - 2433
PB  - IEEE Operations Center
CY  - Piscataway, NJ
ER  - 
TY  - JOUR
A1  - Yoshinobu, T.
A1  - Yasuhito, U.
A1  - Iwasaki, H.
A1  - Näther, Niko
A1  - Schöning, Michael Josef
A1  - Koudelka-Hep, M.
T1  - Applications of the light-addressable potentiometric sensor to microfluidic devices
JF  - Digest of technical papers : September 12 - 15, 2004, Rome, Italy, Pontificia Universitas Sancto Thoma Aquinate in Urbe / [conference chairperson: C. Di Natale].
Y1  - 2004
SN  - 88-7621-282-5
N1  - Eurosensors ; (18, 2004, Roma)
SP  - 434
EP  - 437
CY  - Roma
ER  - 
TY  - JOUR
A1  - Yoshinobu, T.
A1  - Ui, Y.
A1  - Iwasaki, H.
A1  - Näther, Niko
A1  - Koudelka-Hep, M.
A1  - Schöning, Michael Josef
T1  - Potentiometric imaging in a microfluidic channel
JF  - Biomedizinische Technik. 49 (2004), H. 2
Y1  - 2004
SN  - 0932-4666
SP  - 998
EP  - 999
ER  - 
TY  - JOUR
A1  - Yoshinobu, T.
A1  - Schöning, Michael Josef
A1  - Finger, F.
A1  - Moritz, W.
A1  - Iwasaki, H.
T1  - Fabrication of thin-film LAPS with amorphous silicon
JF  - Sensors. 4 (2004), H. 10
Y1  - 2004
SN  - 1424-8220
SP  - 163
EP  - 169
ER  - 
TY  - JOUR
A1  - Weber, Hans-Joachim
A1  - Mo, Xiumei
T1  - Electrospinning P(LLA-CL) nanofiber: a tubular scaffold fabrication with circumferential alignment / Xiumei Mo, Hans-Joachim Weber
JF  - Contributions from 6th Austrian Polymer Meeting : Vienna, Austria, September 15 - 17, 2003 / Symposium ed.: W. H. Binder
Y1  - 2004
N1  - Österreichische Polymertage <6, 2003, Wien>. - (Macromolecular symposia ; 217,1)
SP  - 413
EP  - 416
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Weber, Hans-Joachim
A1  - Hekmat, K.
A1  - Zimmermann, T.
A1  - Kampe, S.
T1  - Impact of tranexamic acid vs. aprotinin on blood loss and transfusion requirements after cardiopulmonary bypass: a prospective, randomised, double-blind trial / Hekmat, K. ; Zimmermann, T. ; Kampe, S. ; Kasper, S. M. ; Weber, H. J. ; Geissler, H. J. ; Meh
JF  - Current Medical Research and Opinion. 20 (2004), H. 1
Y1  - 2004
SN  - 0300-7995
SP  - 121
EP  - 126
ER  - 
TY  - JOUR
A1  - Weber, Hans-Joachim
A1  - Bhuju, S.
A1  - Chandra, S.
A1  - Mo, X.
T1  - Fabrication of biodegradable nanofibers for tubular scaffolds in regenerative medicine / Weber, H.-J. ; Bhuju, S. ; Chandra, S. ; Mo, X.
JF  - Biomedizinische Technik. 49 (2004), H. Erg.-Bd. 2, Teil 2
Y1  - 2004
SP  - 1016
EP  - 1017
ER  - 
TY  - JOUR
A1  - Wagner, Torsten
A1  - Schöning, Michael Josef
A1  - Otto, R.
A1  - Yoshinobu, T.
T1  - A handheld 16 channel pen-type LAPS as a platform for (bio-)electrochemical sensing
JF  - Biomedizinische Technik. 49 (2004), H. 2
Y1  - 2004
SN  - 0932-4666
SP  - 996
EP  - 997
ER  -