TY - JOUR A1 - Hirschfeld, J. A. A1 - Lustfeld, H. A1 - Reißel, Martin A1 - Steffen, B. T1 - Tomographic diagnostics of current distributions in a fuel cell stack JF - International Journal of Energy Research Y1 - 2010 SN - 0363-907X VL - 34 IS - 3 SP - 284 EP - 292 ER - TY - CHAP A1 - Heer, Thomas A1 - Redkowitz, Daniel A1 - Kraft, Bodo T1 - Tool Support for the Integration of Light-Weight Ontologies N2 - Abstract of the authors: In many areas of computer science ontologies become more and more important. The use of ontologies for domain modeling often brings up the issue of ontology integration. The task of merging several ontologies, covering specific subdomains, into one united ontology has to be solved. Many approaches for ontology integration aim at automating the process of ontology alignment. However, a complete automation is not feasible, and user interaction is always required. Nevertheless, most ontology integration tools offer only very limited support for the interactive part of the integration process. In this paper, we present a novel approach for the interactive integration of ontologies. The result of the ontology integration is incrementally updated after each definition of a correspondence between ontology elements. The user is guided through the ontologies to be integrated. By restricting the possible user actions, the integrity of all defined correspondences is ensured by the tool we developed. We evaluated our tool by integrating different regulations concerning building design. KW - Ontologie KW - Knowledge Management KW - Ontology Engineering KW - Information Integration Tools KW - Human Factors Y1 - 2008 SN - 978-3-642-00670-8 ER - TY - JOUR A1 - Röhlen, Desiree A1 - Pilas, Johanna A1 - Dahmen, Markus A1 - Keusgen, Michael A1 - Selmer, Thorsten A1 - Schöning, Michael Josef T1 - Toward a Hybrid Biosensor System for Analysis of Organic and Volatile Fatty Acids in Fermentation Processes JF - Frontiers in Chemistry N2 - Monitoring of organic acids (OA) and volatile fatty acids (VFA) is crucial for the control of anaerobic digestion. In case of unstable process conditions, an accumulation of these intermediates occurs. In the present work, two different enzyme-based biosensor arrays are combined and presented for facile electrochemical determination of several process-relevant analytes. Each biosensor utilizes a platinum sensor chip (14 × 14 mm²) with five individual working electrodes. The OA biosensor enables simultaneous measurement of ethanol, formate, d- and l-lactate, based on a bi-enzymatic detection principle. The second VFA biosensor provides an amperometric platform for quantification of acetate and propionate, mediated by oxidation of hydrogen peroxide. The cross-sensitivity of both biosensors toward potential interferents, typically present in fermentation samples, was investigated. The potential for practical application in complex media was successfully demonstrated in spiked sludge samples collected from three different biogas plants. Thereby, the results obtained by both of the biosensors were in good agreement to the applied reference measurements by photometry and gas chromatography, respectively. The proposed hybrid biosensor system was also used for long-term monitoring of a lab-scale biogas reactor (0.01 m³) for a period of 2 months. In combination with typically monitored parameters, such as gas quality, pH and FOS/TAC (volatile organic acids/total anorganic carbonate), the amperometric measurements of OA and VFA concentration could enhance the understanding of ongoing fermentation processes. Y1 - 2018 U6 - https://doi.org/10.3389/fchem.2018.00284 IS - 6 PB - Frontiers CY - Lausanne ER - TY - JOUR A1 - Arreola, Julio A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Toward an immobilization method for spore-based biosensors in oxidative environment JF - Electrochimica Acta Y1 - 2019 U6 - https://doi.org/10.1016/j.electacta.2019.01.148 VL - 302 SP - 394 EP - 401 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Oberländer, Jan A1 - Bromm, Alexander A1 - Wendeler, Luisa A1 - Iken, Heiko A1 - Palomar Duran, Marlena A1 - Greeff, Anton A1 - Kirchner, Patrick A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Towards a biosensor to monitor the sterilisation efficiency of aseptic filling machines JF - Physica status solidi (a) N2 - Sterilisation processes are compulsory in medicine, pharmacy, and food industries to prevent infections of consumers and microbiological contaminations of products. Monitoring the sterilisation by conventional microbiological methods is time- and lab-consuming. To overcome this problem, in this work a novel biosensor has been proposed. The sensor enables a fast method to evaluate sterilisation processes. By means of thin-film technology the sensor's transducer structures in form of IDEs (interdigitated electrodes) have been fabricated on a silicon substrate. Physical characterisation of the developed sensor was done by AFM, SEM, and profilometry. Impedance analyses were conducted for the electrical characterisation. As microbiological layer spores of B. atrophaeus have been immobilised on the sensing structure; spores of this type are a well-known sterilisation test organism. Impedance measurements at a fixed frequency over time were performed to monitor the immobilisation process. A sterilisation process according to aseptic filling machines was applied to demonstrate the sensor functionality. After both, immobilisation and sterilisation, a change in impedance could successfully be detected. Y1 - 2015 U6 - https://doi.org/10.1002/pssa.201431900 SN - 1862-6319 VL - 212 IS - 6 SP - 1299 EP - 1305 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Arzdorf, Michael A1 - Mulchandani, P. A1 - Chen, W. A1 - Mulchandani, A. T1 - Towards a capacitive enzyme sensor for direct determination of organophosphorus pesticides: Fundamentals studies and aspects of development JF - Sensors. 3 (2003), H. 6 Y1 - 2003 SN - 1424-8220 SP - 119 EP - 127 ER - TY - JOUR A1 - Molinnus, Denise A1 - Drinic, Aleksander A1 - Iken, Heiko A1 - Kröger, Nadja A1 - Zinser, Max A1 - Smeets, Ralf A1 - Köpf, Marius A1 - Kopp, Alexander A1 - Schöning, Michael Josef T1 - Towards a flexible electrochemical biosensor fabricated from biocompatible Bombyx mori silk JF - Biosensors and Bioelectronics Y1 - 2021 U6 - https://doi.org/10.1016/j.bios.2021.113204 SN - 0956-5663 VL - 183 IS - Art. 113204 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Reisert, Steffen A1 - Geissler, Hanno A1 - Flörke, Rudolf A1 - Näther, Niko A1 - Wagner, Patrick A1 - Schöning, Michael Josef T1 - Towards a multi-sensor system for the evaluation of aseptic processes employing hydrogen peroxide vapour (H2O2) JF - Physica status solidi (a) : applications and material science. 208 (2011), H. 6 Y1 - 2011 SN - 1862-6319 SP - 1351 EP - 1356 PB - Wiley CY - Weinheim ER - TY - CHAP A1 - Bohrn, U. A1 - Stütz, E. A1 - Fleischer, M. A1 - Schöning, Michael Josef A1 - Wagner, P. ED - Abdelghani, Adnane ED - Schöning, Michael Josef T1 - Towards a paradigm change – mammalian cells as sensitive biosensor layers for the detection of unexpected toxic substances in air T2 - Nanoscale Science and Technology (NS&T´12) : Proceedings Book Humboldt Kolleg ; Tunisia, 17-19 March, 2012 Y1 - 2012 SP - 44 EP - 44 ER - TY - JOUR A1 - Gerhards, M. A1 - Skorupa, S. A1 - Sander, Volker A1 - Pfeiffer, P. A1 - Belloum, A. T1 - Towards a security framework for a WS-HumanTask processor JF - 7th International Conference on Network and Service Management (CNSM), 2011 Paris Y1 - 2011 SN - 978-3-901882-44-9 SP - 1 EP - 5 PB - IEEE CY - New York ER -