TY  - JOUR
A1  - Becker, Meike
A1  - Frauenrath, Tobias
A1  - Hezel, Fabian
A1  - Krombach, Gabriele A.
A1  - Kremer, Ute
A1  - Koppers, Benedikt
A1  - Butenweg, Christoph
A1  - Goemmel, Andreas
A1  - Utting, Jane F.
A1  - Schulz-Menger, Jeanette
A1  - Niendorf, Thoralf
T1  - Comparison of left ventricular function assessment using phonocardiogram- and electrocardiogram-triggered 2D SSFP CINE MR imaging at 1.5 T and 3.0 T
JF  - European Radiology
N2  - Objective: As high-field cardiac MRI (CMR) becomes more widespread the propensity of ECG to interference from electromagnetic fields (EMF) and to magneto-hydrodynamic (MHD) effects increases and with it the motivation for a CMR triggering alternative. This study explores the suitability of acoustic cardiac triggering (ACT) for left ventricular (LV) function assessment in healthy subjects (n=14). Methods: Quantitative analysis of 2D CINE steady-state free precession (SSFP) images was conducted to compare ACT’s performance with vector ECG (VCG). Endocardial border sharpness (EBS) was examined paralleled by quantitative LV function assessment. Results: Unlike VCG, ACT provided signal traces free of interference from EMF or MHD effects. In the case of correct Rwave recognition, VCG-triggered 2D CINE SSFP was immune to cardiac motion effects—even at 3.0 T. However, VCG-triggered 2D SSFP CINE imaging was prone to cardiac motion and EBS degradation if R-wave misregistration occurred. ACT-triggered acquisitions yielded LV parameters (end-diastolic volume (EDV), endsystolic volume (ESV), stroke volume (SV), ejection fraction (EF) and left ventricular mass (LVM)) comparable with those derived fromVCG-triggered acquisitions (1.5 T: ESVVCG=(56± 17) ml, EDVVCG=(151±32)ml, LVMVCG=(97±27) g, SVVCG=(94± 19)ml, EFVCG=(63±5)% cf. ESVACT= (56±18) ml, EDVACT=(147±36) ml, LVMACT=(102±29) g, SVACT=(91± 22) ml, EFACT=(62±6)%; 3.0 T: ESVVCG=(55±21) ml, EDVVCG=(151±32) ml, LVMVCG=(101±27) g, SVVCG=(96±15) ml, EFVCG=(65±7)% cf. ESVACT=(54±20) ml, EDVACT=(146±35) ml, LVMACT= (101±30) g, SVACT=(92±17) ml, EFACT=(64±6)%). Conclusions: ACT’s intrinsic insensitivity to interference from electromagnetic fields renders
KW  - Magnetic resonance imaging (MRI)
KW  - MR-stethoscope
KW  - Magnetic field strength
KW  - Left ventriular function
KW  - Cardiovascular MRI
Y1  - 2010
U6  - http://dx.doi.org/10.1007/s00330-009-1676-z
SN  - 1432-1084 (Onlineausgabe)
SN  - 0938-7994 (Druckausgabe)
VL  - 20
SP  - 1344
EP  - 1355
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Kurz, R.
A1  - Linder, Peter
A1  - Trzewik, Jürgen
A1  - Rüffer, M.
A1  - Artmann, Gerhard
A1  - Digel, Ilya
A1  - Rothermel, A.
A1  - Robitzki, A.
A1  - Temiz Artmann, Aysegül
T1  - Contractile tension and beating rates of self-exciting monolayers and 3D-tissue constructs of neonatal rat cardiomyocytes
JF  - Medical and Biological Engineering and Computing
N2  - The CellDrum technology (The term 'CellDrum technology' includes a couple of slightly different technological setups for measuring lateral mechanical tension in various types of cell monolayers or 3D-tissue constructs) was designed to quantify the contraction rate and mechanical tension of self-exciting cardiac myocytes. Cells were grown either within flexible, circular collagen gels or as monolayer on top of respective 1-mum thin silicone membranes. Membrane and cells were bulged outwards by air pressure. This biaxial strain distribution is rather similar the beating, blood-filled heart. The setup allowed presetting the mechanical residual stress level externally by adjusting the centre deflection, thus, mimicking hypertension in vitro. Tension was measured as oscillating differential pressure change between chamber and environment. A 0.5-mm thick collagen-cardiac myocyte tissue construct induced after 2 days of culturing (initial cell density 2 x 10(4) cells/ml), a mechanical tension of 1.62 +/- 0.17 microN/mm(2). Mechanical load is an important growth regulator in the developing heart, and the orientation and alignment of cardiomyocytes is stress sensitive. Therefore, it was necessary to develop the CellDrum technology with its biaxial stress-strain distribution and defined mechanical boundary conditions. Cells were exposed to strain in two directions, radially and circumferentially, which is similar to biaxial loading in real heart tissues. Thus, from a biomechanical point of view, the system is preferable to previous setups based on uniaxial stretching.
Y1  - 2010
U6  - http://dx.doi.org/10.1007/s11517-009-0552-y
SN  - 1741-0444
VL  - 48
IS  - 1
SP  - 59
EP  - 65
PB  - Springer Nature
CY  - Cham
ER  - 
TY  - JOUR
A1  - Börner, Sebastian
A1  - Funke, Harald
A1  - Hendrick, P.
A1  - Recker, E.
T1  - Control system modifications for a hydrogen fuelled gas-turbine
JF  - ISROMAC 13, 13th International Symposium on Transport Phenomena and Dynamics of Rotating Machinery, Honolulu, HI, US, Apr 4-7, 2010
Y1  - 2010
SN  - 978-1-617-38848-4
SP  - 665
EP  - 670
PB  - Curran
CY  - Red Hook, NY
ER  - 
TY  - JOUR
A1  - Beer, S.
A1  - Streun, M.
A1  - Hombach, T.
A1  - Buehler, J.
A1  - Jahnke, S.
A1  - Khodaverdi, M.
A1  - Larue, H.
A1  - Minwuyelet, S.
A1  - Parl, C.
A1  - Roeb, G.
A1  - Schurr, U.
A1  - Ziemons, Karl
T1  - Design and initial performance of PlanTIS: a high-resolution positron emission tomograph for plants
JF  - Physics in Medicine and Biology
N2  - Positron emitters such as 11C, 13N and 18F and their labelled compounds are widely used in clinical diagnosis and animal studies, but can also be used to study metabolic and physiological functions in plants dynamically and in vivo. A very particular tracer molecule is 11CO2 since it can be applied to a leaf as a gas. We have developed a Plant Tomographic Imaging System (PlanTIS), a high-resolution PET scanner for plant studies. Detectors, front-end electronics and data acquisition architecture of the scanner are based on the ClearPET™ system. The detectors consist of LSO and LuYAP crystals in phoswich configuration which are coupled to position-sensitive photomultiplier tubes. Signals are continuously sampled by free running ADCs, and data are stored in a list mode format. The detectors are arranged in a horizontal plane to allow the plants to be measured in the natural upright position. Two groups of four detector modules stand face-to-face and rotate around the field-of-view. This special system geometry requires dedicated image reconstruction and normalization procedures. We present the initial performance of the detector system and first phantom and plant measurements.
Y1  - 2010
U6  - http://dx.doi.org/10.1088/0031-9155/55/3/006
SN  - 1361-6560
VL  - 55
IS  - 3
SP  - 635
EP  - 646
PB  - IOP
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Funke, Harald
A1  - Robinson, A. E.
A1  - Hendrick, P.
A1  - Wagemakers, R.
T1  - Design and Testing of a Micromix Combustor With Recuperative Wall Cooling for a Hydrogen Fuelled µ-Scale Gas Turbine
JF  - Proceedings of the ASME Turbo Expo 2010 : presented at the 2010 ASME Turbo Expo, June 14 - 18, 2010, Glasgow, UK / sponsored by the International Gas Turbine Institute / Vol. 5: Industrial and cogeneration ; microturbines and small turbomachinery ; oil and gas applications ; wind turbine technology
Y1  - 2010
SN  - 978-0-7918-4400-7
N1  - GT2010-23453 ; ASME Turbo Expo ; (Glasgow) : 2010.06.14-18
SP  - 587
EP  - 596
PB  - ASME
CY  - New York, NY
ER  - 
TY  - JOUR
A1  - Niemüller, Tim
A1  - Ferrein, Alexander
A1  - Beck, Daniel
A1  - Lakemeyer, Gerhard
T1  - Design Principles of the Component-Based Robot Software Framework Fawkes
JF  - Simulation, Modeling, and Programming for Autonomous Robots
Y1  - 2010
N1  - Lecture Notes in Computer Science ; 6472 ; Second International Conference, SIMPAR 2010, Darmstadt, Germany, November 15-18, 2010. Proceedings
SP  - 300
EP  - 311
ER  - 
TY  - JOUR
A1  - Reisert, Steffen
A1  - Henkel, Hartmut
A1  - Schneider, Andreas
A1  - Schäfer, Daniel
A1  - Friedrich, Peter
A1  - Berger, Jörg
A1  - Schöning, Michael Josef
T1  - Development of a handheld sensor system for the online measurement of hydrogen peroxide in aseptic filling systems
JF  - Physica Status Solidi (A). 207 (2010), H. 4
Y1  - 2010
SN  - 1862-6300
N1  - Special Issue: Engineering of Functional Interfaces EnFI 2009
SP  - 913
EP  - 918
ER  - 
TY  - JOUR
A1  - Spelthahn, Heiko
A1  - Schaffrath, Sophie
A1  - Coppe, Thomas
A1  - Rufi, Frederic
A1  - Schöning, Michael Josef
T1  - Development of an electrolyte-insulator-semiconductor (EIS) based capacitive heavy metal sensor for the detection of Pb2+ und Cd2+ ions
JF  - Physica status solidi (a) : applications and material science. 207 (2010), H. 4
Y1  - 2010
SN  - 1862-6300
N1  - Special Issue: Engineering of Functional Interfaces EnFI 2009
SP  - 930
EP  - 934
ER  - 
TY  - JOUR
A1  - Heinzel, Alexander
A1  - Schäfer, Ralf
A1  - Müller, Hans-Wilhelm
A1  - Schieffer, Andre
A1  - Ingenhag, Ariane
A1  - Northoff, Georg
A1  - Franz, Matthias
A1  - Hautzel, Hubertus
T1  - Differential modulation of valence and arousal in high-alexithymic and low-alexithymic individuals
JF  - Neuroreport
N2  - High-alexithymic individuals are characterized by an impaired ability to identify and communicate emotions whereas low-alexithymic individuals have a wide-ranging ability to deal with emotions. This study examined the hypothesis that valence and arousal modifications of emotional stimuli differentially modulate cortical regions in high-alexithymic and low-alexithymic individuals. To this end, 28 high-alexithymic and 25 low-alexithymic individuals were investigated with event-related fMRI using visual emotional stimuli. We found differential neural activations in the dorsal anterior cingulate, the insula and the amygdala. We suggest that these differences may account for the impaired ability of high-alexithymic individuals to appropriately handle emotional stimuli.
Y1  - 2010
U6  - http://dx.doi.org/10.1097/WNR.0b013e32833f38e0
SN  - 1473-558X
VL  - 21
IS  - 15
SP  - 998
EP  - 1002
PB  - Lippincott Williams & Wilkins
CY  - London
ER  - 
TY  - JOUR
A1  - Dobbertin, Matthias
A1  - Eilmann, Britta
A1  - Bleuler, Peter
A1  - Giuggiola, Arnaud
A1  - Graf Pannatier, Elisabeth
A1  - Landolt, Werner
A1  - Schleppi, Patrick
A1  - Rigling, Andreas
T1  - Effect of irrigation on needle morphology, shoot and stem growth in a drought-exposed Pinus sylvestris forest
JF  - Tree Physiology
N2  - In Valais, Switzerland, Scots pines (Pinus sylvestris L.) are declining, mainly following drought. To assess the impact of drought on tree growth and survival, an irrigation experiment was initiated in 2003 in a mature pine forest, approximately doubling the annual precipitation. Tree crown transparency (lack of foliage) and leaf area index (LAI) were annually assessed. Seven irrigated and six control trees were felled in 2006, and needles, stem discs and branches were taken for growth analysis. Irrigation in 2004 and 2005, both with below-average precipitation, increased needle size, area and mass, stem growth and, with a 1-year delay, shoot length. This led to a relative decrease in tree crown transparency (−14%) and to an increase in stand LAI (+20%). Irrigation increased needle length by 70%, shoot length by 100% and ring width by 120%, regardless of crown transparency. Crown transparency correlated positively with mean needle size, shoot length and ring width and negatively with specific leaf area. Trees with high crown transparency (low growth, short needles) experienced similar increases in needle mass and growth with irrigation than trees with low transparency (high growth, long needles), indicating that seemingly declining trees were able to ‘recover’ when water supply became sufficient. A simple drought index before and during the irrigation explained most of the variation found in the parameters for both irrigated and control trees.
Y1  - 2010
U6  - http://dx.doi.org/10.1093/treephys/tpp123
SN  - 1758-4469 (Online)
SN  - 0829-318X (Print)
VL  - 30
IS  - 3
SP  - 346
EP  - 360
PB  - Oxford University Press
CY  - Oxford
ER  -