TY - JOUR A1 - Wang, J. A1 - Krause, R. A1 - Block, K. A1 - Musameh, M. A1 - Mulchandani, A. A1 - Schöning, Michael Josef T1 - Flow injection amperometric detection of OP nerve agents based on organophosphorus-hydrolase biosensor detector JF - Biosensors & Bioelectronics. 18 (2003), H. 2-3 Y1 - 2003 SN - 0956-5663 SP - 255 EP - 260 ER - TY - JOUR A1 - Wagner, Torsten A1 - Miyamoto, K. A1 - Werner, Frederik A1 - Schöning, Michael Josef A1 - Yoshinobu, T. T1 - Flexible electrochemical imaging with “zoom-in” functionality by using a new type of light-addressable potentiometric sensor Y1 - 2011 N1 - 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference (TRANSDUCERS) , Date: 5-9 June 2011 SP - 2133 EP - 2135 PB - IEEE CY - New York ER - TY - JOUR A1 - Vahidpour, Farnoosh A1 - Oberländer, Jan A1 - Schöning, Michael Josef T1 - Flexible Calorimetric Gas Sensors for Detection of a Broad Concentration Range of Gaseous Hydrogen Peroxide: A Step Forward to Online Monitoring of Food-Package Sterilization Processes JF - Phys. Status Solidi A N2 - In this study, flexible calorimetric gas sensors are developed for specificdetection of gaseous hydrogen peroxide (H₂O₂) over a wide concentrationrange, which is used in sterilization processes for aseptic packaging industry.The flexibility of these sensors is an advantage for identifying the chemical components of the sterilant on the corners of the food boxes, so-called “coldspots”, as critical locations in aseptic packaging, which are of great importance. These sensors are fabricated on flexible polyimide films by means of thin-film technique. Thin layers of titanium and platinum have been deposited on polyimide to define the conductive structures of the sensors. To detect the high-temperature evaporated H₂O₂, a differential temperature set-up is proposed. The sensors are evaluated in a laboratory-scaled sterilizationsystem to simulate the sterilization process. The concentration range of the evaporated H₂O₂ from 0 to 7.7% v/v was defined and the sensors have successfully detected high as well as low H₂O₂ concentrations with a sensitivity of 5.04 °C/% v/v. The characterizations of the sensors confirm their precise fabrication, high sensitivity and the novelty of low H₂O₂ concentration detections for future inline monitoring of food-package sterilization. Y1 - 2018 U6 - http://dx.doi.org/10.1002/pssa.201800044 VL - 215 IS - 15 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Werner, Frederik A1 - Schusser, Sebastian A1 - Spalthahn, Heiko A1 - Wagner, Torsten A1 - Yoshinobu, Tatsuo A1 - Schöning, Michael Josef T1 - Field-programmable gate array based controller for multi spot light-addressable potentiometric sensors with integrated signal correction mode JF - Electrochimica Acta N2 - A light-addressable potentiometric sensor (LAPS) can measure the concentration of one or several analytes at the sensor surface simultaneously in a spatially resolved manner. A modulated light pointer stimulates the semiconductor structure at the area of interest and a responding photocurrent can be read out. By simultaneous stimulation of several areas with light pointers of different modulation frequencies, the read out can be performed at the same time. With the new proposed controller electronic based on a field-programmable gate array (FPGA), it is possible to control the modulation frequencies, phase shifts, and light brightness of multiple light pointers independently and simultaneously. Thus, it is possible to investigate the frequency response of the sensor, and to examine the analyte concentration by the determination of the surface potential with the help of current/voltage curves and phase/voltage curves. Additionally, the ability to individually change the light intensities of each light pointer is used to perform signal correction. Y1 - 2011 U6 - http://dx.doi.org/10.1016/j.electacta.2011.03.012 SN - 0013-4686 VL - 56 IS - 26 SP - 9656 EP - 9660 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Poghossian, Arshak A1 - Abouzar, Maryam H. A1 - Amberger, F. A1 - Mayer, D. A1 - Han, Y. A1 - Ingebrandt, S. A1 - Offenhäusser, A. A1 - Schöning, Michael Josef T1 - Field-effect sensors with charged macromolecules: Characterisation by capacitance–voltage, constant-capacitance, impedance spectroscopy and atomic-force microscopy methods JF - Biosensors and Bioelectronics. 22 (2007), H. 9-10 Y1 - 2007 SN - 0956-5663 N1 - Selected Papers from the Ninth World Congress On Biosensors. Toronto, Canada 10 - 12 May 2006, Alice X. J . Tang SP - 2100 EP - 2107 ER - TY - JOUR A1 - Poghossian, Arshak A1 - Jablonski, Melanie A1 - Molinnus, Denise A1 - Wege, Christina A1 - Schöning, Michael Josef T1 - Field-Effect Sensors for Virus Detection: From Ebola to SARS-CoV-2 and Plant Viral Enhancers JF - Frontiers in Plant Science N2 - Coronavirus disease 2019 (COVID-19) is a novel human infectious disease provoked by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Currently, no specific vaccines or drugs against COVID-19 are available. Therefore, early diagnosis and treatment are essential in order to slow the virus spread and to contain the disease outbreak. Hence, new diagnostic tests and devices for virus detection in clinical samples that are faster, more accurate and reliable, easier and cost-efficient than existing ones are needed. Due to the small sizes, fast response time, label-free operation without the need for expensive and time-consuming labeling steps, the possibility of real-time and multiplexed measurements, robustness and portability (point-of-care and on-site testing), biosensors based on semiconductor field-effect devices (FEDs) are one of the most attractive platforms for an electrical detection of charged biomolecules and bioparticles by their intrinsic charge. In this review, recent advances and key developments in the field of label-free detection of viruses (including plant viruses) with various types of FEDs are presented. In recent years, however, certain plant viruses have also attracted additional interest for biosensor layouts: Their repetitive protein subunits arranged at nanometric spacing can be employed for coupling functional molecules. If used as adapters on sensor chip surfaces, they allow an efficient immobilization of analyte-specific recognition and detector elements such as antibodies and enzymes at highest surface densities. The display on plant viral bionanoparticles may also lead to long-time stabilization of sensor molecules upon repeated uses and has the potential to increase sensor performance substantially, compared to conventional layouts. This has been demonstrated in different proof-of-concept biosensor devices. Therefore, richly available plant viral particles, non-pathogenic for animals or humans, might gain novel importance if applied in receptor layers of FEDs. These perspectives are explained and discussed with regard to future detection strategies for COVID-19 and related viral diseases. Y1 - 2020 U6 - http://dx.doi.org/10.3389/fpls.2020.598103 VL - 11 IS - Article 598103 SP - 1 EP - 14 PB - Frontiers CY - Lausanne ER - TY - JOUR A1 - Poghossian, Arshak A1 - Abouzar, Maryam H. A1 - Sakkari, M. A1 - Kassab, T. A1 - Han, Y. A1 - Ingebrandt, S. A1 - Offenhäusser, A. A1 - Schöning, Michael Josef T1 - Field-effect sensors for monitoring the layer-by-layer adsorption of charged macromolecules JF - Sensors and Actuators B: Chemical. 118 (2006), H. 1-2 Y1 - 2006 SN - 0925-4005 N1 - Eurosensors XIX - Eurosensors XIX - The 19th European Conference on Solid-State Transducers SP - 163 EP - 170 ER - TY - JOUR A1 - Yoshinobu, Tatsuo A1 - Miyamoto, Ko-ichiro A1 - Wagner, Torsten A1 - Schöning, Michael Josef T1 - Field-effect sensors combined with the scanned light pulse technique: from artificial olfactory images to chemical imaging technologies JF - Chemosensors N2 - The artificial olfactory image was proposed by Lundström et al. in 1991 as a new strategy for an electronic nose system which generated a two-dimensional mapping to be interpreted as a fingerprint of the detected gas species. The potential distribution generated by the catalytic metals integrated into a semiconductor field-effect structure was read as a photocurrent signal generated by scanning light pulses. The impact of the proposed technology spread beyond gas sensing, inspiring the development of various imaging modalities based on the light addressing of field-effect structures to obtain spatial maps of pH distribution, ions, molecules, and impedance, and these modalities have been applied in both biological and non-biological systems. These light-addressing technologies have been further developed to realize the position control of a faradaic current on the electrode surface for localized electrochemical reactions and amperometric measurements, as well as the actuation of liquids in microfluidic devices. KW - visualization KW - light-addressing technologies KW - scanned light pulse technique KW - field-effect structure KW - MOS KW - metal-oxide-semiconductor structure KW - catalytic metal KW - electronic nose KW - gas sensor KW - artificial olfactory image Y1 - 2024 U6 - http://dx.doi.org/10.3390/chemosensors12020020 SN - 2227-9040 N1 - This article belongs to the Special Issue "An Exciting Journey of Chemical Sensors and Biosensors: A Theme Issue in Honor of Professor Ingemar Lundström" Corresponding author: Tatsuo Yoshinobu, Michael J. Schöning VL - 12 IS - 2 PB - MDPI CY - Basel ER - TY - JOUR A1 - Abouzar, Maryam H. A1 - Ingebrandt, S. A1 - Poghossian, Arshak A1 - Zhang, Y. A1 - Moritz, W. A1 - Schöning, Michael Josef T1 - Field-effect nanoplate capacitive pH sensor based on SOI structure JF - Semiconductor micro- and nanoelectronics : Proceedings of the Seventh International Conference , Tsakhcadzor, Armenia July 3-5 2009 Y1 - 2009 SP - 55 EP - 58 ER - TY - JOUR A1 - Gun, Jenny A1 - Schöning, Michael Josef A1 - Abouzar, Maryam H. A1 - Poghossian, Arshak A1 - Katz, Evgeny T1 - Field-Effect Nanoparticle-Based Glucose Sensor on a Chip: Amplification Effect of Coimmobilized Redox Species JF - Electroanalysis. 20 (2008), H. 16 Y1 - 2008 SN - 1521-4109 SP - 1748 EP - 1753 ER -