TY - JOUR A1 - Zhubanova, Azhar A. A1 - Aknazarov, S. K. A1 - Mansurov, Zulkhair A1 - Digel, Ilya A1 - Kozhalakova, A. A. A1 - Akimbekov, Nuraly S. A1 - O'Heras, Carlos A1 - Tazhibayeva, S. A1 - Artmann, Gerhard A1 - Temiz Artmann, Aysegül T1 - Adsorption of bacterial Lipopolysaccharides and blood plasma proteins on modified carbonized materials N2 - Bacterial lipopolysaccharides (endotoxins) show strong biological effects at very low concentrations in human beings and many animals when entering the blood stream. These include affecting structure and function of organs and cells, changing metabolic functions, raising body temperature, triggering the coagulation cascade, modifying hemodynamics and causing septic shock. Because of this toxicity, the removal of even minute amounts is essential for safe parenteral administration of drugs and also for septic shock patients' care. The absence of a general method for endotoxin removal from liquid interfaces urgently requires finding new methods and materials to overcome this gap. Nanostructured carbonized plant parts is a promising material that showed good adsorption properties due to its vast pore network and high surface area. The aim of this study was comparative measurement of endotoxin- and blood proteins-related adsorption rate and adsorption capacity for different carboneous materials produced at different temperatures and under different surface modifications. As a main surface modificator, positively cbarged polymer, polyethileneimine (PEl) was used. Activated carbon materials showed good adsorption properties for LPS and some proteins used in the experiments. During the batch experiments, several techniques (dust removal, autoclaving) were used and optimized for improving the material's adsorption behavior. Also, with the results obtained it was possible to differentiate the materials according to their adsorption capacity and kinetic characteristics. Modification of the surface apparently has not affected hemoglobin binding to the adsorbent's surface. Obtained adsorption isotherms can be used as a powerful tool for designing of future column-based setups for blood purification from LPS, which is especially important for septic shock treatment. KW - Kohlenstofffaser KW - Lipopolysaccharide KW - nanostrukturierte carbonisierte Pflanzenteile KW - lipopolysaccharides KW - nanostructured carbonized plant parts Y1 - 2010 ER - TY - JOUR A1 - Staat, Manfred A1 - Sponagel, Stefan A1 - Nguyen, Nhu Huynh T1 - Experiment and material model for soft tissue materials JF - Constitutive models for rubber VI : proceedings of the sixth European Conference on Constitutive Models for Rubber, Dresden, Germany, 7 - 10 September 2009 / eds. Gert Heinrich ... Y1 - 2010 SN - 978-0-415-56327-7 SP - 465 EP - 470 PB - CRC Press CY - Boca Raton [u.a.] ER - TY - JOUR A1 - Gerhards, M. A1 - Belloum, A. A1 - Berretz, F. A1 - Sander, Volker A1 - Skorupa, S. T1 - A history-tracing XML-based provenance framework for workflows Y1 - 2010 SN - 978-1-4244-8989-3 N1 - Workflows in Support of Large-Scale Science (WORKS), 2010 5th Workshop on SP - 1 EP - 10 ER - TY - JOUR A1 - Funke, Harald A1 - Börner, Sebastian A1 - Robinson, A. A1 - Hendrick, P. A1 - Recker, E. T1 - Low NOx H2 combustion for industrial gas turbines of various power ranges JF - 5th International Gas Turbine Conference ETN-IGTC, ETN-2010-42, Brussels, Belgium, October 2010 Y1 - 2010 ER - TY - JOUR A1 - Recker, Elmar A1 - Bosschaerts, Walter A1 - Wagemakers, Rolf A1 - Hendrick, Patrick A1 - Funke, Harald A1 - Börner, Sebastian T1 - Experimental study of a round jet in cross-flow at low momentum ratio JF - 15th International Symposium on Applications of Laser Techniques to Fluid Mechanics Lisbon, Portugal, 05-08 July, 2010 - 1 Y1 - 2010 SP - 1 EP - 13 ER - TY - JOUR A1 - Funke, Harald A1 - Robinson, A. E. A1 - Hendrick, P. A1 - Wagemakers, R. T1 - Design and Testing of a Micromix Combustor With Recuperative Wall Cooling for a Hydrogen Fuelled µ-Scale Gas Turbine JF - Proceedings of the ASME Turbo Expo 2010 : presented at the 2010 ASME Turbo Expo, June 14 - 18, 2010, Glasgow, UK / sponsored by the International Gas Turbine Institute / Vol. 5: Industrial and cogeneration ; microturbines and small turbomachinery ; oil and gas applications ; wind turbine technology Y1 - 2010 SN - 978-0-7918-4400-7 N1 - GT2010-23453 ; ASME Turbo Expo ; (Glasgow) : 2010.06.14-18 SP - 587 EP - 596 PB - ASME CY - New York, NY ER - TY - JOUR A1 - Ferrein, Alexander T1 - golog.lua: Towards a Non-Prolog Implementation of Golog for Embedded Systems JF - Cognitive Robotics / Lakemeyer, Gerhard (ed.) Y1 - 2010 N1 - Dagstuhl Seminar Proceedings ; 10081 SP - 1 EP - 15 ER - TY - JOUR A1 - Ferrein, Alexander T1 - golog.lua: Towards a Non-Prolog Implementation of Golog for Embedded Systems Y1 - 2010 SP - 20 EP - 28 ER - TY - JOUR A1 - Kurz, R. A1 - Linder, Peter A1 - Trzewik, Jürgen A1 - Rüffer, M. A1 - Artmann, Gerhard A1 - Digel, Ilya A1 - Rothermel, A. A1 - Robitzki, A. A1 - Temiz Artmann, Aysegül T1 - Contractile tension and beating rates of self-exciting monolayers and 3D-tissue constructs of neonatal rat cardiomyocytes JF - Medical and Biological Engineering and Computing N2 - The CellDrum technology (The term 'CellDrum technology' includes a couple of slightly different technological setups for measuring lateral mechanical tension in various types of cell monolayers or 3D-tissue constructs) was designed to quantify the contraction rate and mechanical tension of self-exciting cardiac myocytes. Cells were grown either within flexible, circular collagen gels or as monolayer on top of respective 1-mum thin silicone membranes. Membrane and cells were bulged outwards by air pressure. This biaxial strain distribution is rather similar the beating, blood-filled heart. The setup allowed presetting the mechanical residual stress level externally by adjusting the centre deflection, thus, mimicking hypertension in vitro. Tension was measured as oscillating differential pressure change between chamber and environment. A 0.5-mm thick collagen-cardiac myocyte tissue construct induced after 2 days of culturing (initial cell density 2 x 10(4) cells/ml), a mechanical tension of 1.62 +/- 0.17 microN/mm(2). Mechanical load is an important growth regulator in the developing heart, and the orientation and alignment of cardiomyocytes is stress sensitive. Therefore, it was necessary to develop the CellDrum technology with its biaxial stress-strain distribution and defined mechanical boundary conditions. Cells were exposed to strain in two directions, radially and circumferentially, which is similar to biaxial loading in real heart tissues. Thus, from a biomechanical point of view, the system is preferable to previous setups based on uniaxial stretching. Y1 - 2010 U6 - https://doi.org/10.1007/s11517-009-0552-y SN - 1741-0444 VL - 48 IS - 1 SP - 59 EP - 65 PB - Springer Nature CY - Cham ER - TY - JOUR A1 - Kozhalakova, A. A. A1 - Zhubanova, Azhar A. A1 - Mansurov, Z. A. A1 - Digel, Ilya A1 - Tazhibayeva, S. M. A1 - Artmann, Gerhard A1 - Temiz Artmann, Aysegül T1 - Adsorption of bacterial lipopolysaccharides on carbonized rice shell JF - Science of Central Asia (2010) Y1 - 2010 SP - 50 EP - 54 ER -