TY  - THES
A1  - Reyes Ochoa, Leonel
T1  - Engineering aspects of a parabolic trough collector field with direct steam generation and an organic rankine cycle
Y1  - 2014
N1  - Aachen, Fachhochsch., Masterarbeit, 2014
PB  - Fachhochschule Aachen
CY  - Aachen
ER  - 
TY  - JOUR
A1  - Almajhdi, Fahad N.
A1  - Senger, Tilo
A1  - Amer, Haitham M.
A1  - Gissmann, Lutz
A1  - Öhlschläger, Peter
T1  - Design of a highly effective therapeutic HPV16 E6/E7-specific DNA vaccine: optimization by different ways of sequence rearrangements (Shuffling)
JF  - PLOS one
N2  - Persistent infection with the high-risk Human Papillomavirus type 16 (HPV 16) is the causative event for the development of cervical cancer and other malignant tumors of the anogenital tract and of the head and neck. Despite many attempts to develop therapeutic vaccines no candidate has entered late clinical trials. An interesting approach is a DNA based vaccine encompassing the nucleotide sequence of the E6 and E7 viral oncoproteins. Because both proteins are consistently expressed in HPV infected cells they represent excellent targets for immune therapy. Here we report the development of 8 DNA vaccine candidates consisting of differently rearranged HPV-16 E6 and E7 sequences within one molecule providing all naturally occurring epitopes but supposedly lacking transforming activity. The HPV sequences were fused to the J-domain and the SV40 enhancer in order to increase immune responses. We demonstrate that one out of the 8 vaccine candidates induces very strong cellular E6- and E7- specific cellular immune responses in mice and, as shown in regression experiments, efficiently controls growth of HPV 16 positive syngeneic tumors. This data demonstrates the potential of this vaccine candidate to control persistent HPV 16 infection that may lead to malignant disease. It also suggests that different sequence rearrangements influence the immunogenecity by an as yet unknown mechanism.
Y1  - 2014
U6  - https://doi.org/10.1371/journal.pone.0113461
SN  - 1932-6203
VL  - 11
IS  - 9
PB  - PLOS
CY  - San Francisco
ER  - 
TY  - BOOK
A1  - Kern, Alexander
A1  - Wettingfeld, Jürgen
T1  - Blitzschutzsysteme 1 : allgemeine Grundsätze, Risikomanagement, Schutz von baulichen Anlagen und Personen ; Erläuterungen zu den Normen DIN EN 62305-1 (VDE 0185-305-1):2011-10, DIN EN 62305-2 (VDE 0185-305-2):2013-02, DIN EN 62305-3 (VDE 0185-305-3):2011-10. (VDE-Schriftenreihe Normen verständlich ; 44)
Y1  - 2014
SN  - 978-3-8007-3511-2
PB  - VDE-Verl.
CY  - Berlin [u.a.]
ER  - 
TY  - BOOK
A1  - Tietze, Jürgen
T1  - Übungsbuch zur angewandten Wirtschaftsmathematik : Aufgaben, Testklausuren und ausführliche Lösungen. -  9., überarb. u. erw. Aufl.
Y1  - 2014
SN  - 978-3-658-06874-5 ; 978-3-658-06873-8
PB  - Vieweg + Teubner
CY  - Wiesbaden
ET  - 9., überarb. u. erw. Aufl.
ER  - 
TY  - JOUR
A1  - Wollert, Jörg
T1  - Funkstandards für Sensornetzwerke
JF  - Elektronik : Fachmedium für industrielle Anwender und Entwickler
Y1  - 2014
SN  - 0013-5658
VL  - Bd. 63
IS  - H. 12
SP  - 36
EP  - 41
PB  - WEKA-Fachmedien
CY  - Haar
ER  - 
TY  - JOUR
A1  - Wollert, Jörg
T1  - Echtzeit-Ethernet : Protokoll-Reigen
JF  - Elektronik : Fachmedium für industrielle Anwender und Entwickler
Y1  - 2014
SN  - 0013-5658
VL  - Bd. 63
IS  - H. 26
SP  - 24
EP  - 31
PB  - WEKA-Fachmedien
CY  - Haar
ER  - 
TY  - JOUR
A1  - Wollert, Jörg
T1  - Der Embedded Wireless-Report
JF  - Elektronik : Fachmedium für industrielle Anwender und Entwickler ; Sonderh. Wireless : Fachmedium für Entwicklungen funkbasierter Systeme
Y1  - 2014
SN  - 0013-5658
SP  - 18
EP  - 25
PB  - WEKA-Fachmedien
CY  - Haar
ER  - 
TY  - JOUR
A1  - Wollert, Jörg
T1  - Echtzeit-Ethernet mit Standardtechnik
JF  - Elektronik : Fachmedium für industrielle Anwender und Entwickler ; Sonderh. Embedded : Fachmagazin für die Entwicklung von Embedded-Systemen
Y1  - 2014
SN  - 0013-5658
VL  - Bd. 63
IS  - H. 12
SP  - 28
EP  - 32
PB  - WEKA-Fachmedien
CY  - Haar
ER  - 
TY  - CHAP
A1  - Huber, Max
A1  - Rau, Sebastian
A1  - Streblow, Rita
A1  - Wollert, Jörg
A1  - Müller, Dirk
T1  - Lüftungskanäle als Funkstrecke
T2  - Jahreskolloquium Kommunikation in der Automation (KommA 2014) : Lemgo, 18.11.2014 / Jürgen Jasperneite ... (Hrsg.)
Y1  - 2014
SN  - 978-3-9814062-4-5
SP  - 1
EP  - 8
ER  - 
TY  - JOUR
A1  - Wollert, Jörg
T1  - Feldbustechnologie
JF  - Factory : der Durchblick in der Technik
Y1  - 2014
SP  - Publ. online
PB  - WEKA-Industriemedien
CY  - Wien
ER  -