TY - CHAP A1 - Seibler, Jost A1 - Schwenk, Frieder T1 - Transgenic RNAi Applications in the Mouse T2 - Methods in Enzymology : Guide to Techniques in Mouse Development, Part B: Mouse Molecular Genetics. 2nd Edition Y1 - 2010 SN - 978-0-12-384880-2 N1 - Methods in Enzymology : Vol. 477 SP - 367 EP - 386 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Bode, J. A1 - Bartsch, J. A1 - Boulikas, T. A1 - Iber, M. A1 - Mielke, C. A1 - Schübeler, D. A1 - Seibler, Jost A1 - Benham, C. T1 - Transcription-promoting genomic sites in mammalia: their elucidation and architectural principles JF - Gene therapy & molecular biology Y1 - 1998 SN - 1529-9120 VL - 1 IS - 1 SP - 1 EP - 29 ER - TY - JOUR A1 - Raab, Monika A1 - Kappel, Sven A1 - Krämer, Andrea A1 - Sanhaji, Mourad A1 - Matthess, Yves A1 - Kurunci-Csacsko, Elisabeth A1 - Calzada-Wack, Julia A1 - Rathkolb, Birgit A1 - Rosman, Jan A1 - Adler, Thure A1 - Busch, Dirk H. A1 - Esposito, Irene A1 - Fuchs, Helmut A1 - Gailus-Durner, Valérie A1 - Klingenspor, Martin A1 - Wolf, Eckhard A1 - Sänger, Nicole A1 - Prinz, Florian A1 - Hrabe de Angelis, Martin A1 - Seibler, Jost A1 - Yuan, Juping A1 - Bergmann, Martin A1 - Knecht, Rainald A1 - Kreft, Bertolt A1 - Strebhardt, Klaus T1 - Toxicity modelling of Plk1-targeted therapies in genetically engineered mice and cultured primary mammalian cells JF - Nature Communications Y1 - 2011 U6 - http://dx.doi.org/10.1038/ncomms1395 SN - 2041-1723 VL - 2 IS - 395 SP - 1 EP - 11 PB - Nature CY - London ER - TY - JOUR A1 - Bode, Jürgen A1 - Schlake, Thomas A1 - Iber, Michaela A1 - Schübeler, Dirk A1 - Seibler, Jost A1 - Snezhkov, Evgeney A1 - Nikolaev, Lev T1 - The transgeneticist's toolbox: novel methods for the targeted modification of eukaryotic genomes JF - Biological Chemistry Y1 - 2000 U6 - http://dx.doi.org/10.1515/BC.2000.103 SN - 1431-6730 VL - 381 IS - 9-10 SP - 801 EP - 813 ER - TY - JOUR A1 - Glaser, Stefan A1 - Lubitz, Sandra A1 - Loveland, Kate L. A1 - Ohbo, Kazu A1 - Robb, Lorraine A1 - Schwenk, Frieder A1 - Seibler, Jost A1 - Roellig, Daniela A1 - Kranz, Andrea A1 - Anastassiadis, Konstantinos A1 - Stewart, A. Francis T1 - The histone 3 lysine 4 methyltransferase, Mll2, is only required briefly in development and spermatogenesis JF - Epigenetics & Chromatin Y1 - 2009 U6 - http://dx.doi.org/10.1186/1756-8935-2-5 SN - 1756-8935 VL - 2 IS - 5 SP - 1 EP - 16 ER - TY - JOUR A1 - Feng, Yong-Qing A1 - Seibler, Jost A1 - Alami, Raouf A1 - Eisen, Andrew A1 - Westerman, Karen A. A1 - Leboulch, Philippe A1 - Fiering, Steven A1 - Bouhassira, Eric E. T1 - Site-specific chromosomal integration in mammalian cells: highly efficient CRE recombinase-mediated cassette exchange JF - Journal of Molecular Biology Y1 - 1999 U6 - http://dx.doi.org/10.1006/jmbi.1999.3113 SN - 0022-2836 VL - 292 IS - 4 SP - 779 EP - 785 ER - TY - JOUR A1 - Seibler, Jost A1 - Küter-Luks, Birgit A1 - Kern, Heidrun A1 - Streu, Sandra A1 - Plum, Leona A1 - Maurer, Jan A1 - Kühn, Ralf A1 - Brüning, Jens C. A1 - Schwenk, Frieder T1 - Single copy shRNA configuration for ubiquitous gene knockdown in mice JF - Nucleic Acids Research Y1 - 2005 U6 - http://dx.doi.org/10.1093/nar/gni065 SN - 1362-4962 VL - 33 IS - 7 SP - e67 ER - TY - JOUR A1 - Seibler, Jost A1 - Kleinridders, Andre A1 - Küter-Luks, Birgit A1 - Niehaves, Sandra A1 - Brüning, Jens C. A1 - Schwenk, Frieder T1 - Reversible gene knockdown in mice using a tight, inducible shRNA expression system JF - Nucleic Acids Research Y1 - 2007 U6 - http://dx.doi.org/10.1093/nar/gkm122 SN - 1362-4962 VL - 35 IS - 7 SP - e54 ER - TY - JOUR A1 - Seibler, Jost A1 - Zevnik, Branko A1 - Küter-Luks, Birgit A1 - Andreas, Susanne A1 - Kern, Heidrun A1 - Hennek, Thomas A1 - Rode, Anja A1 - Heimann, Cornelia A1 - Faust, Nicole A1 - Kauselmann, Gunther A1 - Schoor, Michael A1 - Jaenisch, Rudolf A1 - Rajewsky, Klaus A1 - Kühn, Ralf A1 - Schwenk, Frieder T1 - Rapid generation of inducible mouse mutants JF - Nucleic Acids Research Y1 - 2003 U6 - http://dx.doi.org/10.1093/nar/gng012 SN - 1362-4962 VL - 33 IS - 4 SP - e12 ER - TY - JOUR A1 - Hasegawa, Maki A1 - Kapelyukh, Yury A1 - Tahara, Harunobu A1 - Seibler, Jost A1 - Rode, Anja A1 - Krueger, Sylvia A1 - Lee, Dongtao N. A1 - Wolf, C. Roland A1 - Scheer, Nico T1 - Quantitative prediction of human pregnane X receptor and cytochrome P450 3A4 mediated drug-drug interaction in a novel multiple humanized mouse line JF - Molecular Pharmacology Y1 - 2011 U6 - http://dx.doi.org/10.1124/mol.111.071845 SN - 1521-0111 VL - 80 IS - 33 SP - 518 EP - 528 PB - ASPET CY - Bethesda, Md. ER -