TY - JOUR A1 - Tippkötter, Nils A1 - Deterding, A. A1 - Ulber, Roland T1 - Determination of acetic acid in fermentation broth by gas-diffusion technique JF - Engineering in Life Sciences N2 - Due to the interfering effects of acetic acid in many fermentation processes, a gas-diffusion technique was developed for the online determination of acetic acid. The measurements were accomplished with a flow diffusion analysis (FDA) unit from the TRACE Analytics GmbH, Braunschweig, Germany. The diffusion analysis is based on the UV-absorbance of acetic acid at 205 nm. The measurement was achieved by the separation of an acceptor and a carrier stream (acidified fermentation broth) using a gas permeable polytetrafluoroethylene (PTFE) membrane, whereby broth constituents that would otherwise disturb the UV-measurement of acetic acid, are held back efficiently. Merely, the fermentation by-products, e.g. formic acid, is capable of diffusing through the membrane. While formic acid can disturb the measurement, carbon dioxide does not absorb at 205 nm. The method operates with time-dependent sample enrichment. During the analysis, a small volume of the acceptor stream is stopped for a defined time interval in the acceptor chamber. During this period, the gaseous acetic acid diffuses through the membrane and is enriched in the acceptor chamber. Subsequently after the enrichment, the acceptor stream flows through a UV-detector. The intensity of the signal is proportional to the acetic acid concentration. Online measurements in bioreactors via a sterile filtration probe have been accomplished. A linear calibration in the range of 0.5–5.0 g/L acetic acid with a relative standard deviation of <5 % was obtained. A sampling rate of 8 samples per hour was possible. The system was applied for the determination of acetic acid in E. coli fermentation broth. The instrument is easy to clean, very user-friendly and does not require any toxic or expensive reagents. Y1 - 2008 U6 - https://doi.org/10.1002/elsc.200820227 VL - 8 IS - 1, Special Issue: Technical Systems for the Use in Life Sciences SP - 62 EP - 67 ER - TY - CHAP A1 - Schuh, Günther A1 - Gottschalk, Sebastian A1 - Höhne, Tim A1 - Attig, Philipp ED - Mitsuishi, M. T1 - Further Potentials of Smart Logistics T2 - Manufacturing Systems and Technologies for the New Frontier Y1 - 2008 SN - 978-1-84800-267-8 SN - 978-1-84800-266-1 (Printausgabe) U6 - https://doi.org/10.1007/978-1-84800-267-8_18 N1 - The 41St Cirp Conference On Manufacturing Systems, May 26-28, 2008, Tokyo, Japan SP - 93 EP - 96 PB - Springer CY - London ER - TY - CHAP A1 - Tippkötter, Nils A1 - Roikaew, W. A1 - Ulber, Roland T1 - An automated pilot plant for the bioengineering processing of concentrated whey T2 - European BioPerspectives : in cooperation with BIOTECHNICA 2008 : 7 - 9 October 2008 Hannover, Germany ; book of abstracts ; abstracts, poster programme Y1 - 2008 SP - 98 PB - Dechema CY - Frankfurt am Main ER - TY - BOOK A1 - Drumm, Christian T1 - Improving Schema Mapping by Exploiting Domain Knowledge Y1 - 2008 N1 - Karlsruhe, Univ., Diss., 2008 ER - TY - BOOK A1 - Moosdorf, Andreas T1 - The determinants of international knowledge transfer effectiveness - conceptual advances and empirical verification Y1 - 2008 N1 - The University of Leeds > Leeds University Business School. Thesis (PhD) ER - TY - THES A1 - Tran, Thanh Ngoc T1 - Limit and shakedown analysis of plates and shells including uncertainties Y1 - 2008 N1 - Chemnitz, Techn. Univ., Diss., 2008 ER - TY - JOUR A1 - Tippkötter, Nils A1 - Roikaew, W. A1 - Ulber, Roland T1 - Nitrate removal from whey concentrate with biotechnological regeneration of the waste water JF - European dairy magazine : EDM Y1 - 2008 SN - 0936-6318 IS - 1 SP - 30 EP - 32 ER - TY - JOUR A1 - Lerchl, Alexander A1 - Krüger, Heike A1 - Niehaus, Michael A1 - Streckert, Joachim R. A1 - Bitz, Andreas A1 - Hansen, Volkert T1 - Effects of mobile phone electromagnetic fields at nonthermal SAR values on melatonin and body weight of Djungarian hamsters (Phodopus sungorus) JF - Journal of Pineal Research Y1 - 2008 U6 - https://doi.org/10.1111/j.1600-079X.2007.00522.x SN - 1600-079X VL - 44 IS - 3 SP - 267 EP - 272 ER - TY - CHAP A1 - Osterhage, Hannes A1 - Bialonski, Stephan A1 - Staniek, Matthäus A1 - Schindler, Kaspar A1 - Wagner, Tobias A1 - Elger, Christian E. A1 - Lehnertz, Klaus T1 - Bivariate and multivariate time series analysis techniques and their potential impact for seizure prediction T2 - Seizure Prediction in Epilepsy: From Basic Mechanisms to Clinical Applications Y1 - 2008 SN - 978-3-527-62519-2 U6 - https://doi.org/10.1002/9783527625192.ch15 SP - 189 EP - 208 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Schindler, Kaspar A. A1 - Bialonski, Stephan A1 - Horstmann, Marie-Therese A1 - Elger, Christian E. A1 - Lehnertz, Klaus T1 - Evolving functional network properties and synchronizability during human epileptic seizures JF - Chaos: An Interdisciplinary Journal of Nonlinear Science Y1 - 2008 U6 - https://doi.org/10.1063/1.2966112 SN - 1089-7682 VL - 18 IS - 3 SP - 033119 ER -