TY - JOUR A1 - Kowalski, Julia A1 - McElwaine, Jim N. T1 - Shallow two-component gravity-driven flows with vertical variation JF - Journal of Fluid Mechanics Y1 - 2013 SN - 0022-1120 VL - 714 SP - 434 EP - 462 PB - Cambridge Univ. Press CY - Cambridge ER - TY - JOUR A1 - Bassam, Rasha A1 - Digel, Ilya A1 - Hescheler, Jürgen A1 - Temiz Artmann, Aysegül A1 - Artmann, Gerhard T1 - Effects of spermine NONOate and ATP on protein aggregation: light scattering evidences JF - BMC Biophysics Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?10.1186/2046-1682-6-1 SN - 2046-1682 SP - 1 EP - 14 PB - BioMed Central CY - London ER - TY - JOUR A1 - Werner, Frederik A1 - Takenaga, Shoko A1 - Taki, Hidenori A1 - Sawada, Kazuaki A1 - Schöning, Michael Josef T1 - Comparison of label-free ACh-imaging sensors based on CCD and LAPS JF - Sensors and Actuators B: Chemical (2012) N2 - Semiconductor-based chemical imaging sensors, like the light-addressable potentiometric sensor (LAPS) or the pH-imaging sensor based on a charge-coupled device (CCD), are becoming a powerful tool for label-free imaging of biological phenomena. We have proposed a polyion-based enzymatic membrane to develop an acetylcholine (ACh) imaging sensor for neural cell-activity observations. In this study, a CCD-type ACh-imaging sensor and a LAPS-type ACh-imaging sensor were fabricated and the prospect of both sensors was clarified by making a comparison of their basic characteristics. Y1 - 2013 SN - 0925-4005 VL - 177 SP - 745 EP - 752 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Tran, Thanh Ngoc A1 - Staat, Manfred T1 - An Edge-Based Smoothed Finite Element Method for Primal-Dual Shakedown Analysis of Structures Under Uncertainties JF - Limit State of Materials and Structures : Direct Methods 2. Saxcé, Géry de (Hrsg.) Y1 - 2013 SN - 978-94-007-5424-9 SP - 89 EP - 102 PB - Springer CY - Dordrecht ER - TY - JOUR A1 - Pham, Phu Tinh A1 - Staat, Manfred T1 - An Upper Bound Algorithm for Limit and Shakedown Analysis of Bounded Linearly Kinematic Hardening Structures JF - Limit State of Materials and Structures : Direct Methods 2. Saxcé, Géry de (Hrsg.) Y1 - 2013 SN - 978-94-007-5424-9 SP - 71 EP - 87 PB - Springer CY - Dordrecht ER - TY - JOUR A1 - Bohrn, Ulrich A1 - Stütz, Evamaria A1 - Fleischer, Maximilian A1 - Schöning, Michael Josef A1 - Wagner, Patrick T1 - Using a cell-based gas biosensor for investigation of adverse effects of acetone vapors in vitro JF - Biosensors and Bioelectronics. 40 (2013), H. 1 Y1 - 2013 SN - 0956-5663 SP - 393 EP - 400 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Bäcker, Matthias A1 - Rakowski, D. A1 - Poghossian, Arshak A1 - Biselli, Manfred A1 - Wagner, Patrick A1 - Schöning, Michael Josef T1 - Chip-based amperometric enzyme sensor system for monitoring of bioprocesses by flow-injection analysis JF - Journal of Biotechnology N2 - A microfluidic chip integrating amperometric enzyme sensors for the detection of glucose, glutamate and glutamine in cell-culture fermentation processes has been developed. The enzymes glucose oxidase, glutamate oxidase and glutaminase were immobilized by means of cross-linking with glutaraldehyde on platinum thin-film electrodes integrated within a microfluidic channel. The biosensor chip was coupled to a flow-injection analysis system for electrochemical characterization of the sensors. The sensors have been characterized in terms of sensitivity, linear working range and detection limit. The sensitivity evaluated from the respective peak areas was 1.47, 3.68 and 0.28 μAs/mM for the glucose, glutamate and glutamine sensor, respectively. The calibration curves were linear up to a concentration of 20 mM glucose and glutamine and up to 10 mM for glutamate. The lower detection limit amounted to be 0.05 mM for the glucose and glutamate sensor, respectively, and 0.1 mM for the glutamine sensor. Experiments in cell-culture medium have demonstrated a good correlation between the glutamate, glutamine and glucose concentrations measured with the chip-based biosensors in a differential-mode and the commercially available instrumentation. The obtained results demonstrate the feasibility of the realized microfluidic biosensor chip for monitoring of bioprocesses. Y1 - 2013 U6 - http://dx.doi.org/10.1016/j.jbiotec.2012.03.014 SN - 0168-1656 VL - 163 IS - 4 SP - 371 EP - 376 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Funke, Harald A1 - Börner, Sebastian A1 - Hendrick, P. A1 - Recker, E. A1 - Elsing, R. ED - DeLuca, Luigi T. T1 - Development and integration of a scalable low NOx combustion chamber for a hydrogen fuelled aero gas turbine T2 - Progress in Propulsion Physics. - Vol. 4 Y1 - 2013 SN - 978-2-7598-0876-2 U6 - http://dx.doi.org/10.1051/eucass/201304357 N1 - 4th European Conference for Aero-Space Sciences : July 4 - 8, 2011, St Petersburg, Russia ; EUCASS <4, 2011, St. Petersburg> SP - 357 EP - 372 PB - EDP Sciences CY - [Les Ulis] ER - TY - JOUR A1 - Akimbekov, Nuraly Shardarbekovich A1 - Mansurov, Zulkhair A1 - Jandosov, J. A1 - Digel, Ilya A1 - Gossmann, Matthias A1 - Artmann, Gerhard A1 - Temiz Artmann, Aysegül A1 - Zhubanova, Azhar A. T1 - Wound healing activity of carbonized rice husk N2 - The carbonized rice husk (CRH) was evaluated for its wound healing activity in rats using excision models. In this study, the influences of CRH on wound healing in rat skin in vivo and cellular behavior of human dermal fibroblasts in vitro were investigated. The obtained results showed that the CRH treatment promoted wound epithelization in rats and exhibited moderate inhibition of cell proliferation in vitro. CRH with lanolin oil treated wounds were found to epithelize faster as compared to controls. KW - Wundheilung KW - Epithel KW - Fibroblast KW - carbonized rice husk KW - wound healing KW - epithelization KW - human dermal fibroblasts Y1 - 2013 PB - Trans Tech Publications, Switzerland CY - Bäch ER -