TY - JOUR A1 - Buniatyan, Vahe Vazgen A1 - Abouzar, Maryam H. A1 - Martirosyan, Norayr W. A1 - Schubert, Jürgen A1 - Gevorgian, Spartak A1 - Schöning, Michael Josef A1 - Poghossian, Arshak T1 - pH-sensitive properties of barium strontium titanate (BST) thin films prepared by pulsed laser deposition technique JF - Physica Status Solidi (A) N2 - pH-sensitive properties of barium strontium titanate (BST) high-k thin films as alternative gate material for field-effect capacitive (bio-)chemical sensors based on an electrolyte-insulator-semiconductor system have been investigated. The BST films of different compositions (Ba0.31Sr0.69TiO3, Ba0.25Sr0.75TiO3 and Mg-doped Ba0.8Sr0.2Mg0.1Ti0.9O3) were deposited by pulsed laser deposition technique from targets fabricated by self-propagating high-temperature synthesis. The realised sensors have been electrochemically characterised by means of impedance-spectroscopy, capacitance–voltage and constant-capacitance method. The sensors possess a Nernstian-like pH sensitivity in the concentration range between pH 3 and 11 with a response time of 5–10 s. An equivalent circuit model for the BST-based capacitive field-effect sensor is discussed. Y1 - 2010 U6 - https://doi.org/10.1002/pssa.200983310 SN - 1862-6300 N1 - Special Issue: Engineering of Functional Interfaces EnFI 2009 VL - 207 IS - 4 SP - 824 EP - 830 PB - Wiley-VCH CY - Berlin ER - TY - JOUR A1 - Siqueira, José R. Jr. A1 - Bäcker, Matthias A1 - Poghossian, Arshak A1 - Zucolotto, Valtencir A1 - Oliveira, Osvaldo N. Jr. A1 - Schöning, Michael Josef T1 - Associating biosensing properties with the morphological structure of multilayers containing carbon nanotubes on field-effect devices JF - Physica Status Solidi (A) N2 - The control of molecular architecture provided by the layer-by-layer (LbL) technique has led to enhanced biosensors, in which advantageous features of distinct materials can be combined. Full optimization of biosensing performance, however, is only reached if the film morphology is suitable for the principle of detection of a specific biosensor. In this paper, we report a detailed morphology analysis of LbL films made with alternating layers of single-walled carbon nanotubes (SWNTs) and polyamidoamine (PAMAM) dendrimers, which were then covered with a layer of penicillinase (PEN). An optimized performance to detect penicillin G was obtained with 6-bilayer SWNT/PAMAM LbL films deposited on p-Si-SiO2-Ta2O5 chips, used in biosensors based on a capacitive electrolyte-insulator-semiconductor (EIS) and a light-addressable potentiometric sensor (LAPS) structure, respectively. Field-emission scanning electron microscopy (FESEM) and atomic force microscopy (AFM) images indicated that the LbL films were porous, with a large surface area due to interconnection of SWNT into PAMAM layers. This morphology was instrumental for the adsorption of a larger quantity of PEN, with the resulting LbL film being highly stable. The experiments to detect penicillin were performed with constant-capacitance (ConCap) and constant-current (CC) measurements for EIS and LAPS sensors, respectively, which revealed an enhanced detection signal and sensitivity of ca. 100 mV/decade for the field-effect sensors modified with the PAMAM/SWNT LbL film. It is concluded that controlling film morphology is essential for an enhanced performance of biosensors, not only in terms of sensitivity but also stability and response time. Y1 - 2010 U6 - https://doi.org/10.1002/pssa.200983301 SN - 1862-6300 N1 - Special Issue: Engineering of Functional Interfaces EnFI 2009 VL - 207 IS - 4 SP - 781 EP - 786 PB - Wiley-VCH CY - Berlin ER - TY - JOUR A1 - Gossla, Ulrich A1 - Buttel, Luc A1 - Wahrmund, Holger A1 - Mehlig, Bernd T1 - Bemessung, Anwendung und Qualitätssicherung von Stahlfaserspritzbeton im Tunnelbau JF - Beton- und Stahlbetonbau N2 - Die Spritzbetonbauweise hat sich im Tunnelbau seit Jahren bewährt. Spritzbeton wird als unbewehrter Beton, in Verbindung mit Bewehrung sowie als Stahlfaserspritzbeton eingesetzt. Bei den meisten Tunnelschalen aus Stahlfaserspritzbeton werden Stahlfasern derzeit nur als konstruktive Bewehrung verwendet. Die Faserzugabe führt zu einer nennenswerten Erhöhung der Bruchenergie und somit zu einer höheren Zähigkeit des sonst spröden Materials und damit zu einer höheren Sicherheit. Stahlfaserspritzbeton kann auch anstelle von Spritzbeton mit statisch erforderlicher Mattenbewehrung eingesetzt werden. Die Bemessung erfolgt dann unter Berücksichtigung der Nachrisszugfestigkeit. Diese kann wie bei Stahlfaserbeton an Biegebalken ermittelt werden, die aus größeren Proben herausgesägt werden. Anhand von verschiedenen Beispielen werden die unterschiedlichen Anwendungen aufgezeigt und die dafür erforderlichen Prüfungen vorgestellt. Y1 - 2010 U6 - https://doi.org/10.1002/best.200900688 SN - 0005-9900 VL - 105 IS - 2 SP - 92 EP - 101 PB - Ernst & Sohn CY - Berlin ER - TY - JOUR A1 - Ullrich, Sebastian A1 - Grottke, Oliver A1 - Rossaint, Rolf A1 - Staat, Manfred A1 - Deserno, Thomas M. A1 - Kuhlen, Torsten T1 - Virtual Needle Simulation with Haptics for Regional Anaesthesia Y1 - 2010 N1 - IEEE Virtual Reality 2010, Workshop on Medical Virtual Environments, Waltham, MA, USA, March 21, 2010 ER - TY - JOUR A1 - Timme, Michael T1 - Mietschuldenfreiheitsbescheinigung durch den bisherigen Vermieter? JF - MDR Monatsschrift für Deutsches Recht N2 - Der VIII. Zivilsenat des BGH hat entschieden, dass ein Mieter von seinem ehemaligen Vermieter keine „Mietschuldenfreiheitsbescheinigung‘‘ verlangen kann, die über eine Quittung für die erhaltenen Mietzahlungen hinausgeht. Der folgende Beitrag untersucht die Konsequenzen der aktuellen Entscheidung. Y1 - 2010 U6 - https://doi.org/10.9785/ovs-mdtr-2010-60 SN - 0340-1812 VL - 64 IS - 2 SP - 60 EP - 61 PB - Verlag Dr. Otto Schmidt CY - Köln ER - TY - JOUR A1 - Timme, Michael A1 - Hülk, Fabian T1 - Schriftform bei Mietvertrag mit einer Aktiengesellschaft JF - Neue Zeitschrift für Gesellschaftsrecht (NZG) Y1 - 2010 SN - 1434-9272 VL - 13 IS - 5 SP - 177 EP - 178 PB - Beck CY - München ER - TY - JOUR A1 - Timme, Michael T1 - Die Schenkung eines Tieres an einen beschränkt Geschäftsfähigen JF - Juristische Arbeitsblätter Y1 - 2010 SN - 0720-6356 SP - 174 EP - 176 PB - Beck CY - München ER - TY - JOUR A1 - Siqueira, Jose R. A1 - Maki, Rafael M. A1 - Paulovich, Fernando V. A1 - Werner, Frederik A1 - Poghossian, Arshak A1 - Oliveira, Maria C. F. de A1 - Zucolotto, Valtencir A1 - Oliveira, Osvaldo N. Jr. A1 - Schöning, Michael Josef T1 - Use of information visualization methods eliminating cross talk in multiple sensing units investigated for a light-addressable potentiometric sensor JF - Analytical Chemistry N2 - The integration of nanostructured films containing biomolecules and silicon-based technologies is a promising direction for reaching miniaturized biosensors that exhibit high sensitivity and selectivity. A challenge, however, is to avoid cross talk among sensing units in an array with multiple sensors located on a small area. In this letter, we describe an array of 16 sensing units of a light-addressable potentiometric sensor (LAPS), which was made with layer-by-layer (LbL) films of a poly(amidomine) dendrimer (PAMAM) and single-walled carbon nanotubes (SWNTs), coated with a layer of the enzyme penicillinase. A visual inspection of the data from constant-current measurements with liquid samples containing distinct concentrations of penicillin, glucose, or a buffer indicated a possible cross talk between units that contained penicillinase and those that did not. With the use of multidimensional data projection techniques, normally employed in information visualization methods, we managed to distinguish the results from the modified LAPS, even in cases where the units were adjacent to each other. Furthermore, the plots generated with the interactive document map (IDMAP) projection technique enabled the distinction of the different concentrations of penicillin, from 5 mmol L−1 down to 0.5 mmol L−1. Data visualization also confirmed the enhanced performance of the sensing units containing carbon nanotubes, consistent with the analysis of results for LAPS sensors. The use of visual analytics, as with projection methods, may be essential to handle a large amount of data generated in multiple sensor arrays to achieve high performance in miniaturized systems Y1 - 2010 U6 - https://doi.org/10.1021/ac9024076 SN - 0003-2700 VL - 82 IS - 1 SP - 61 EP - 65 PB - ACS Publications CY - Washington ER - TY - JOUR A1 - Grottke, O. A1 - Braunschweig, T. A1 - Philippen, B. A1 - Gatzweiler, Karl-Heinz A1 - Gronloh, N. A1 - Staat, Manfred A1 - Rossaint, R. A1 - Tolba, R. T1 - A new model for blunt liver injuries in the swine JF - European Surgical Research N2 - Background: To elaborate the impact of new haemostatic agents we developed an instrument for the pressure-controlled induction of blunt liver injuries in a porcine animal model. Materials and Methods: A dilutional coagulopathy of 80% of animal blood volume was induced in 9 anaesthetized pigs. Animals were randomly assigned to be injured with a force of 112 Newton (N) (n = 1), 224 ± 19 N (n = 4) or 355 ± 35 N (n = 4). The impact of injury was measured by blood loss, survival time and coagulation parameters. Liver histology was obtained to evaluate the degree of liver injury. Results: The profound haemodilution resulted in a significant alteration of all coagulation parameters. After inflicting the injury with 355 ± 35 N, both the survival time (30 ± 9 min; p = 0.006) and blood loss (68 ± 16 ml min–1, p = 0.002) were significantly different as compared to injuries with 224 ± 19 N (survival time: 76 ± 20 min, blood loss: 23 ± 4 ml min–1). In contrast, an injury with 112 N led to an insignificant blood loss of only 239 ml. Conclusion: We developed a pressure-controlled clamp that allows for the induction of blunt liver traumas with highly reproducible injuries with a positive correlation with blood loss and survival. Y1 - 2010 U6 - https://doi.org/10.1159/000265053 SN - 1421-9921 VL - 44 IS - 2 SP - 65 EP - 73 PB - Karger CY - Basel ER - TY - BOOK A1 - Siedenbiedel, Georg T1 - Organisation Y1 - 2010 SN - 978-3-8252-8413-8 N1 - UTB ; 8413 : Betriebswirtschaftslehre PB - Lucius & Lucius CY - Stuttgart ER -