TY  - PAT
A1  - Artmann, Gerhard
A1  - Linder, Peter
A1  - Bayer, Robin
A1  - Gossmann, Matthias
T1  - Celldrum electrode arrangement for measuring mechanical stress [Patent of invention]
N2  - The invention pertains to a CellDrum electrode arrangement for measuring mechanical stress, comprising a mechanical holder (1 ) and a non-conductive membrane (4), whereby the membrane (4) is at least partially fixed at its circumference to the mechanical holder (1), keeping it in place when the membrane (4) may bend due to forces acting on the membrane (4), the mechanical holder (1) and the membrane (4) forming a container, whereby the membrane (1) within the container comprises an cell- membrane compound layer or biological material (3) adhered to the deformable membrane 4 which in response to stimulation by an agent may exert mechanical stress to the membrane (4) such that the membrane bending stage changes whereby the container may be filled with an electrolyte, whereby an electric contact (2) is arranged allowing to contact said electrolyte when filled into to the container, whereby within a predefined geometry to the fixing of the membrane (4) an electrode (7) is arranged, whereby the electrode (7) is electrically insulated with respect to the electric contact (2) as well as said electrolyte, whereby mechanical stress due to an agent may be measured as a change in capacitance.
Y1  - 2017
N1  - Patent auch unter EP3403090, CN109477828, US2019033245 und LU92948 veröffentlicht.
PB  - WIPO
CY  - Geneva
ER  - 
TY  - CHAP
A1  - Samuelsson, K.
A1  - Scheer, Nico
A1  - Wilson, I.
A1  - Wolf, C.R.
A1  - Henderson, C.J.
ED  - Chackalamannil, Samuel
T1  - Genetically Humanized Animal Models
T2  - Comprehensive Medicinal Chemistry III. 3rd Edition
N2  - Genetically humanized mice for proteins involved in drug metabolism and toxicity and mice engrafted with human hepatocytes are emerging as promising in vivo models for improved prediction of the pharmacokinetic, drug–drug interaction, and safety characteristics of compounds in humans. This is an overview on the genetically humanized and chimeric liver-humanized mouse models, which are illustrated with examples of their utility in drug metabolism and toxicity studies. The models are compared to give guidance for selection of the most appropriate model by highlighting advantages and disadvantages to be carefully considered when used for studies in drug discovery and development.
KW  - Chimeric liver-humanized mice
KW  - Drug distribution
KW  - Drug metabolism
KW  - Toxicology
KW  - Knockout mice
Y1  - 2017
SN  - 978-0-12-803201-5
U6  - http://dx.doi.org/10.1016/B978-0-12-409547-2.12376-5
SP  - 130
EP  - 149
PB  - Elsevier
CY  - Saint Louis
ER  - 
TY  - JOUR
A1  - Wilson, Ian D.
A1  - Wilson, Claire E.
A1  - Scheer, Nico
A1  - Dickie, A.P.
A1  - Schreiter, K.
A1  - Wilson, E. M.
A1  - Riley, R. J.
A1  - Wehr, R.
A1  - Bial, J.
T1  - The Pharmacokinetics and Metabolism of Lumiracoxib in Chimeric Humanized and Murinized FRG Mice
JF  - Biochemical pharmacology
Y1  - 2017
U6  - http://dx.doi.org/10.1016/j.bcp.2017.03.015
SN  - 1873-2968
VL  - Volume 135
SP  - 139
EP  - 150
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - CHAP
A1  - Kroll-Ludwigs, Kathrin
T1  - Small Claims Regulation
T2  - European Encyclopedia of Private International Law
Y1  - 2017
SN  - 9781782547228
PB  - Edward Elgar Publishing
CY  - Cheltenham, UK
ER  - 
TY  - CHAP
A1  - Kroll-Ludwigs, Kathrin
T1  - Names of individuals
T2  - European Encyclopedia of Private International Law
Y1  - 2017
SN  - 9781782547228
PB  - Edward Elgar Publishing
CY  - Cheltenham, UK
ER  - 
TY  - CHAP
A1  - Herrmann, Ulf
A1  - Kearney, D.
A1  - Röger, M.
A1  - Prahl, C.
T1  - System performance measurements
T2  - The Performance of Concentrated Solar Power (CSP) Systems : Modelling, Measurement and Assessment
N2  - This chapter introduces performance and acceptance testing and describes state-of-the-art tools, methods, and instruments to assess the plant performance or realize plant acceptance testing. The status of the development of standards for performance assessment is given.
KW  - Performance measurement
KW  - Acceptance tests
KW  - Plant efficiency
Y1  - 2017
SN  - 978-0-08-100448-7
U6  - http://dx.doi.org/https://doi.org/10.1016/B978-0-08-100447-0.00005-5
SP  - 115
EP  - 165
PB  - Woodhead Publishing
CY  - Duxford
ER  - 
TY  - CHAP
A1  - Sauerborn, Markus
A1  - Liebenstund, Lena
A1  - Raue, Markus
A1  - Mang, Thomas
A1  - Herrmann, Ulf
A1  - Dueing, Andreas
T1  - Analytic method for material aging and quality analyzing to forecast long time stability of plastic micro heliostat components
T2  - AIP Conference Proceedings
Y1  - 2017
U6  - http://dx.doi.org/10.1063/1.4984388
VL  - 1850
IS  - 1
SP  - 030045-1
EP  - 030045-8
ER  - 
TY  - JOUR
A1  - Richter, Charlotte
A1  - Braunstein, Bjoern
A1  - Winnard, Andrew
A1  - Nasser, Mona
A1  - Weber, T.
T1  - Human Biomechanical and Cardiopulmonary Responses to Partial Gravity – A Systematic Review
JF  - Frontiers in physiology
Y1  - 2017
U6  - http://dx.doi.org/10.3389/fphys.2017.00583
IS  - 8, article 583
ER  - 
TY  - CHAP
A1  - Finger, Felix
A1  - Braun, Carsten
A1  - Bil, Cees
T1  - A Review of Configuration Design for Distributed Propulsion Transitioning VTOL Aircraft
T2  - Asia-Pacific International Symposium on Aerospace Technology 2017, APISAT 2017, Seoul, Korea
Y1  - 2017
ER  - 
TY  - CHAP
A1  - Finger, Felix
A1  - Braun, Carsten
A1  - Bil, Cees
T1  - The Impact of Electric Propulsion on the Performance of VTOL UAVs
T2  - Deutscher Luft- und Raumfahrtkongress 2017, DLRK , München
Y1  - 2017
ER  -