TY - JOUR A1 - Jacobs, Stephan T1 - CSCW for Requirements Engineering - Requirements Engineering for CSCW JF - Proceedings of the Third European Conference on Computer Supported Cooperative Work : 13 - 17 September 1993, Milan, Italy ; ECSCW ' 93 / ed. by Giorgio de Michelis ... Y1 - 1993 SN - 0-7923-2447-1 N1 - ECSCW <3, 1993, Milano> ; [Workshop "CSCW Tools and Technologies: Definging Research Agendas] PB - Kluwer CY - Dordrecht [u.a.] ER - TY - JOUR A1 - Jacobs, Stephan T1 - Von aktionsorientiertem zu entscheitungsorientierten Workflow JF - Workshop "Unterstützung organisatorischer Prozesse durch CSCW" : 4. - 5. November 1993, Westfälische Wilhelms-Universität Münster / [Institut für Wirtschaftsinformatik, Westfälische Wilhelms-Universität Münster]. Stefan Kirn ... (Hrsg.) Y1 - 1993 N1 - Arbeitsberichte / Institut für Wirtschaftsinformatik, Westfälische Wilhelms-Universität Münster CY - Münster ER - TY - JOUR A1 - Jacobs, Stephan T1 - The Teamwork Approach in Requirements Engineering JF - The nature of requirements engineering / Matthias Jarke ... (Hrsg.) Y1 - 1999 SN - 3-8265-6174-0 PB - Shaker CY - Aachen ER - TY - JOUR A1 - Jacobs, Stephan T1 - Agilität in Großprojekten durch „Integration Driven Design“ : ein Erfahrungsbericht JF - Softwaretechnik-Trends (STT) N2 - Der folgende Bericht fasst Erfahrungen zusammen, die in großen Entwicklungsprojekten der Firma Ericsson über mehrere Jahre gesammelt wurden. Ziel war dabei nicht, agile Methoden und Techniken einzusetzen - Agilität war zu der Zeit noch kein Hype-Thema. Vielmehr wurden Schwächen in den eigenen Projekten identifiziert und verbessert. Der Erfahrungsbericht vergleicht Verbesserungen in diesen Projekten mit den Ansätzen der agilen Entwicklung. Als Ergebnis werden folgende Punkte festgehalten: Erstens, einige Praktiken und Werte der agilen Entwicklung lassen sich auch in Großprojekten einsetzen. Zweitens, bei der Skalierung für Großprojekte werden diese Praktiken langsamer getaktet. Drittens, agile Entwicklung ist nicht nur eine Reihe von Praktiken und Werten, agile Entwicklung ist vielmehr auch eine Frage der Entwicklungs- und Projektkultur. Diese kulturelle Änderung lässt sich in Großprojekten deutlich langsamer umsetzen. Y1 - 2010 SN - 0720-8928 VL - 30 IS - 3 PB - GI - Gesellschaft für Informatik CY - Bonn ER - TY - JOUR A1 - Jablonski, Melanie A1 - Poghossian, Arshak A1 - Severin, Robin A1 - Keusgen, Michael A1 - Wege, Christian A1 - Schöning, Michael Josef T1 - Capacitive Field-Effect Biosensor Studying Adsorption of Tobacco Mosaic Virus Particles JF - Micromachines N2 - Plant virus-like particles, and in particular, tobacco mosaic virus (TMV) particles, are increasingly being used in nano- and biotechnology as well as for biochemical sensing purposes as nanoscaffolds for the high-density immobilization of receptor molecules. The sensitive parameters of TMV-assisted biosensors depend, among others, on the density of adsorbed TMV particles on the sensor surface, which is affected by both the adsorption conditions and surface properties of the sensor. In this work, Ta₂O₅-gate field-effect capacitive sensors have been applied for the label-free electrical detection of TMV adsorption. The impact of the TMV concentration on both the sensor signal and the density of TMV particles adsorbed onto the Ta₂O₅-gate surface has been studied systematically by means of field-effect and scanning electron microscopy methods. In addition, the surface density of TMV particles loaded under different incubation times has been investigated. Finally, the field-effect sensor also demonstrates the label-free detection of penicillinase immobilization as model bioreceptor on TMV particles. KW - capacitive field-effect sensor KW - plant virus detection KW - tobacco mosaic virus (TMV) KW - TMV adsorption KW - Ta₂O₅ gate Y1 - 2021 U6 - https://doi.org/10.3390/mi12010057 VL - 12 IS - 1 PB - MDPI CY - Basel ER - TY - JOUR A1 - Jablonowski, Nicolai David A1 - Kollmann, Tobias A1 - Nabel, Moritz A1 - Damm, Tatjana A1 - Klose, Holger A1 - Müller, Michael A1 - Bläsing, Marc A1 - Seebold, Sören A1 - Krafft, Simone A1 - Kuperjans, Isabel A1 - Dahmen, Markus A1 - Schurr, Ulrich T1 - Valorization of Sida (Sida hermaphrodita) biomass for multiple energy purposes JF - GCB [Global Change Biology] Bioenergy N2 - The performance and biomass yield of the perennial energy plant Sida hermaphrodita (hereafter referred to as Sida) as a feedstock for biogas and solid fuel was evaluated throughout one entire growing period at agricultural field conditions. A Sida plant development code was established to allow comparison of the plant growth stages and biomass composition. Four scenarios were evaluated to determine the use of Sida biomass with regard to plant development and harvest time: (i) one harvest for solid fuel only; (ii) one harvest for biogas production only; (iii) one harvest for biogas production, followed by a harvest of the regrown biomass for solid fuel; and (iv) two consecutive harvests for biogas production. To determine Sida's value as a feedstock for combustion, we assessed the caloric value, the ash quality, and melting point with regard to DIN EN ISO norms. The results showed highest total dry biomass yields of max. 25 t ha⁻¹, whereas the highest dry matter of 70% to 80% was obtained at the end of the growing period. Scenario (i) clearly indicated the highest energy recovery, accounting for 439 288 MJ ha⁻¹; the energy recovery of the four scenarios from highest to lowest followed this order: (i) ≫ (iii) ≫ (iv) > (ii). Analysis of the Sida ashes showed a high melting point of >1500 °C, associated with a net calorific value of 16.5–17.2 MJ kg⁻¹. All prerequisites for DIN EN ISO norms were achieved, indicating Sida's advantage as a solid energy carrier without any post-treatment after harvesting. Cell wall analysis of the stems showed a constant lignin content after sampling week 16 (July), whereas cellulose had already reached a plateau in sampling week 4 (April). The results highlight Sida as a promising woody, perennial plant, providing biomass for flexible and multipurpose energy applications. Y1 - 2016 U6 - https://doi.org/10.1111/gcbb.12346 SN - 1757-1707 (online) SN - 1757-1693 (print) N1 - Special Issue: Perennial biomass crops for a resource constrained world VL - 9 IS - 1 SP - 202 EP - 214 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Itabashi, Akinori A1 - Kosaka, Naoki A1 - Miyamoto, Ko-ichiro A1 - Wagner, Torsten A1 - Schöning, Michael Josef T1 - High-speed chemical imaging system based on front-side-illuminated LAPS JF - Sensors and actuators B: Chemical N2 - The chemical imaging sensor is a semiconductor-based chemical sensor that can visualize the spatial distribution of specific ions on the sensing surface. The conventional chemical imaging system based on the light-addressable potentiometric sensor (LAPS), however, required a long time to obtain a chemical image, due to the slow mechanical scan of a single light beam. For high-speed imaging, a plurality of light beams modulated at different frequencies can be employed to measure the ion concentrations simultaneously at different locations on the sensor plate by frequency division multiplex (FDM). However, the conventional measurement geometry of back-side illumination limited the bandwidth of the modulation frequency required for FDM measurement, because of the low-pass filtering characteristics of carrier diffusion in the Si substrate. In this study, a high-speed chemical imaging system based on front-side-illuminated LAPS was developed, which achieved high-speed spatiotemporal recording of pH change at a rate of 70 frames per second. Y1 - 2013 U6 - https://doi.org/10.1016/j.snb.2013.03.016 SN - 1873-3077 VL - 182 SP - 315 EP - 321 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Ismail, A.B.M. A1 - Harada, T. A1 - Yoshinobu, T. A1 - Iwasaki, H. A1 - Schöning, Michael Josef A1 - Lüth, H. T1 - Investigation of pulsed laser-deposited Al2O3 as a high pH-sensitive layer for LAPS-based biosensing applications JF - Sensors and Actuators B. 71 (2000), H. 3 Y1 - 2000 SN - 0925-4005 SP - 169 EP - 172 ER - TY - JOUR A1 - Ingebrandt, S. A1 - Han, Y. A1 - Nakamura, F. A1 - Poghossian, Arshak A1 - Schöning, Michael Josef A1 - Offenhäusser, A. T1 - Label-free detection of single nucleotide polymorphisms utilizing the differential transfer function of field-effect transistors JF - Biosensors and Bioelectronics. 22 (2007), H. 12 Y1 - 2007 SN - 0956-5663 SP - 2834 EP - 2840 ER - TY - JOUR A1 - Infantino, Angelo A1 - Paulßen, Elisabeth A1 - Mostacci, Domiziano A1 - Schaffer, Paul A1 - Trinczek, Michael A1 - Hoehr, Cornelia T1 - Assessment of the production of medical isotopes using the Monte Carlo code FLUKA: Simulations against experimental measurements JF - Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms N2 - The Monte Carlo code FLUKA is used to simulate the production of a number of positron emitting radionuclides, ¹⁸F, ¹³N, ⁹⁴Tc, ⁴⁴Sc, ⁶⁸Ga, ⁸⁶Y, ⁸⁹Zr, ⁵²Mn, ⁶¹Cu and ⁵⁵Co, on a small medical cyclotron with a proton beam energy of 13 MeV. Experimental data collected at the TR13 cyclotron at TRIUMF agree within a factor of 0.6 ± 0.4 with the directly simulated data, except for the production of ⁵⁵Co, where the simulation underestimates the experiment by a factor of 3.4 ± 0.4. The experimental data also agree within a factor of 0.8 ± 0.6 with the convolution of simulated proton fluence and cross sections from literature. Overall, this confirms the applicability of FLUKA to simulate radionuclide production at 13 MeV proton beam energy. Y1 - 2016 U6 - https://doi.org/10.1016/j.nimb.2015.10.067 SN - 1872-9584 VL - 366 SP - 117 EP - 123 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Inagaki, Akiko A1 - Sleddens-Linkels, Esther A1 - Wassenaar, Evelyne A1 - Ooms, Marja A1 - Cappellen, Wiggert A. van A1 - Hoeijmakers, Jan H. J. A1 - Seibler, Jost A1 - Vogt, Thomas F. A1 - Shin, Myung K. A1 - Grootegoed, J. Anton A1 - Baarends, Willy M. T1 - Meiotic functions of RAD18 JF - Journal of Cell Science Y1 - 2011 U6 - https://doi.org/10.1242/jcs.081968 SN - 1477-9137 VL - 124 IS - 16 SP - 2837 EP - 2850 PB - Company of Biologists Limited CY - Cambridge ER - TY - JOUR A1 - Immel, Timo A1 - Grützke, Martin A1 - Späte, Anne-Katrin A1 - Groth, Ulrich A1 - Öhlschläger, Peter A1 - Huhn, Thomas T1 - Synthesis and X-ray structure analysis of a heptacoordinate titanium(IV)-bis-chelate with enhanced in vivo antitumor efficacy JF - Chemical Communications N2 - Chelate stabilization of a titanium(IV)–salan alkoxide by ligand exchange with 2,6-pyridinedicarboxylic acid (dipic) resulted in heptacoordinate complex 3 which is not redox-active, stable on silica gel and has increased aqueous stability. 3 is highly toxic in HeLa S3 and Hep G2 and has enhanced antitumor efficacy in a mouse cervical-cancer model. Y1 - 2012 U6 - https://doi.org/10.1039/C2CC31624B SN - 1364-548X VL - 48 IS - 46 SP - 5790 EP - 5792 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Immel, Timo A. A1 - Groth, Ulrich A1 - Huhn, Thomas A1 - Öhlschläger, Peter T1 - Titanium salan complexes displays strong antitumor properties in vitro and in vivo in mice JF - PLoS ONE N2 - The anticancer activity of titanium complexes has been known since the groundbreaking studies of Köpf and Köpf-Maier on titanocen dichloride. Unfortunately, possibly due to their fast hydrolysis, derivatives of titanocen dichloride failed in clinical studies. Recently, the new family of titanium salan complexes containing tetradentate ONNO ligands with anti-cancer properties has been discovered. These salan complexes are much more stabile in aqueous media. In this study we describe the biological activity of two titanium salan complexes in a mouse model of cervical cancer. High efficiency of this promising complex family was demonstrated for the first time in vivo. From these data we conclude that titanium salan complexes display very strong antitumor properties exhibiting only minor side effects. Our results may influence the chemotherapy with metallo therapeutics in the future. Y1 - 2011 U6 - https://doi.org/10.1371/journal.pone.0017869 VL - 6 IS - 3 PB - Plos CY - San Francisco, California, US ER - TY - JOUR A1 - Ille, F. A1 - Schramm, S. A1 - Adam, M. A1 - Backes, K. A1 - Faber, Christian A1 - Anthrakidis, Anette T1 - Kraft-Wärme-Kälte-Kopplung im Leistungsbereich von 10 kW mit periodisch arbeitender Sorptionsmaschine JF - VDI-Tage der Gebäudetechnik 2008 : Tagung Dortmund, 28. und 29. Mai 2008 / VDI-Gesellschaft Technische Gebäudeausrüstung Y1 - 2008 SN - 978-3-18-092043-6 N1 - VDI-Berichte ; 2043 ; 2. VDI-Tage der Gebäudetechnik 2008, VDI-Gesellschaft Technische Gebäudeausrüstung (VDI-TGA), Dortmund, DE, 28.-29. Mai, 2008 SP - 103 EP - 116 PB - VDI-Verl. CY - Düsseldorf ER - TY - JOUR A1 - Iken, Heiko A1 - Kirsanov, D. A1 - Legin, A. A1 - Schöning, Michael Josef T1 - Novel Thin-Film Polymeric Materials for the Detection of Heavy Metals JF - Procedia Engineering N2 - A variety of transition metals, e.g., copper, zinc, cadmium, lead, etc. are widely used in industry as components for wires, coatings, alloys, batteries, paints and so on. The inevitable presence of transition metals in industrial processes implies the ambition of developing a proper analytical technique for their adequate monitoring. Most of these elements, especially lead and cadmium, are acutely toxic for biological organisms. Quantitative determination of these metals at low activity levels in different environmental and industrial samples is therefore a vital task. A promising approach to achieve an at-side or on-line monitoring on a miniaturized and cost efficient way is the combination of a common potentiometric sensor array with heavy metal-sensitive thin-film materials, like chalcogenide glasses and polymeric materials, respectively. Y1 - 2012 U6 - https://doi.org/10.1016/j.proeng.2012.09.148 SN - 1877-7058 N1 - Part of special issue "26th European Conference on Solid-State Transducers, EUROSENSOR 2012" IS - 47 SP - 322 EP - 325 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Iken, Heiko A1 - Bronder, Thomas A1 - Goretzki, Alexander A1 - Kriesel, Jana A1 - Ahlborn, Kristina A1 - Gerlach, Frank A1 - Vonau, Winfried A1 - Zander, Willi A1 - Schubert, Jürgen A1 - Schöning, Michael Josef T1 - Development of a Combined pH- and Redox-Sensitive Bi-Electrode Glass Thin-Film Sensor JF - physica status solidi a : applications and materials sciences Y1 - 2019 U6 - https://doi.org/10.1002/pssa.201900114 SN - 1862-6319 VL - 216 IS - 12 SP - 1 EP - 8 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Iken, Heiko A1 - Ahlborn, Kristina A1 - Gerlach, Frank A1 - Vonau, Winfried A1 - Zander, Wilhelm A1 - Schubert, Jürgen P. A1 - Schöning, Michael Josef T1 - Development of redox glasses and subsequent processing by means of pulsed laser deposition for realizing silicon-based thin-film sensors JF - Electrochimica acta Y1 - 2013 SN - 1873-3859 (E-Journal); 0013-4686 (Print) SP - Available online 30.8.2013 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Iding, Hans A1 - Siegert, Petra A1 - Mesch, K. A1 - Pohl, Martina T1 - Application of α-keto acid decarboxylases in biotransformations JF - Biochimica et biophysica acta (BBA) - Protein structure and molecular enzymology Y1 - 1998 SN - 1879-2588 (E-Journal); 0167-4838 (Print) VL - Vol. 1385 IS - Iss. 2 SP - 307 EP - 322 ER - TY - JOUR A1 - Iding, Hans A1 - Dünnwald, Thomas A1 - Greiner, Lasse A1 - Liese, Andreas A1 - Müller, Michael A1 - Siegert, Petra A1 - Grötzinger, Joachim A1 - Demir, Ayhan S. A1 - Pohl, Martina T1 - Benzoylformate Decarboxylase from Pseudomonas putida as Stable Catalyst for the Synthesis of Chiral 2-Hydroxy Ketones JF - Chemistry - a European journal Y1 - 2000 SN - 1521-3765 (E-Journal); 0947-6539 (Print) VL - Vol. 6 IS - Iss. 8 SP - 1483 EP - 1495 ER - TY - JOUR A1 - Iber, Michaela A1 - Schübeler, Dirk A1 - Seibler, Jost A1 - Höxter, Maria A1 - Bode, Jürgen T1 - Efficient FACS selection procedure for cells undergoing Flp-mediated site-specific conversions JF - Technical Tips Online Y1 - 1998 U6 - https://doi.org/10.1016/S1366-2120(08)70132-6 VL - 4 IS - 1 SP - 25 EP - 29 ER - TY - JOUR A1 - Hüning, Felix A1 - Wilke, I. A1 - Nakielski, G. A1 - Kotzler, J. T1 - Dynamic conductivity of YBCO thin films from low to very high frequencies / Wilke, I. ; Nakielski, G. ; Kotzler, J. ; Subke, K. O. ; Jaekel, C. ; Hüning, F. ; Roskos, H. G. ; Kurz, Heinrich JF - Applied superconductivity 1997 : proceedings of EUCAS 1997, the Third European Conference on Applied Superconductivity, held in the Netherlands, 30 June - 3 July 1997 / ed. by H. Rogalla Y1 - 1997 SN - 0-7503-0487-1 N1 - Institute of Physics conference series 158 SP - 121 EP - 124 PB - IOP CY - Bristol ER - TY - JOUR A1 - Hüning, Felix A1 - Sparta, K. A1 - Redhammer, G. J. A1 - Roussel, P. T1 - Structural Phase Transition in the 2D Spin Dimer Compound SrCu2(BO3)2 / Sparta, K. ; Redhammer, G. J. ; Roussel, P. ; Heger, G. ; Roth, G. ; Ionescu, A. Lemmens, P. ; Grove, M. ; Güntherrodt, G. ; Hüning, F. ; Lueken, H. ; Kageyama, H. ; Onizuka, K ; Ueda JF - The European Physical Journal B - Condensed Matter and Complex Systems. 19 (2001), H. 4 Y1 - 2001 SN - 1434-6036 SP - 507 EP - 516 PB - - ER - TY - JOUR A1 - Hüning, Felix A1 - Luken, Heiko A1 - Schilder, Herbert A1 - Eifert, Thomas T1 - Magnetochemistry: Compounds and Concepts / Lueken, Heiko ; Schilder, Herbert ; Eifert, Thomas ; Handrick, Klaus ; Hüning, Felix JF - Advances in Solid State Physics. 201 (2001) Y1 - 2001 SP - 515 EP - 532 PB - - ER - TY - JOUR A1 - Hüning, Felix A1 - Leineweber, A. A1 - Jacobs, H. A1 - Lueken, H. T1 - ε-Fe3N: magnetic structure, magnetization and temperature dependent disorder of nitrogen / Leineweber, A. ; Jacobs, H. ; Hüning, F. ; Lueken, H. ; Schilder, H. ; Kockelmann, W. JF - Journal of Alloys and Compounds. 288 (1999), H. 1-2 N2 - ε-Fe3N has been investigated by time-of-flight neutron diffraction (temperature range 4.2–618 K) and SQUID magnetometry (2–700 K, B≤5 T). A ferromagnetic spin structure is observed with magnetic moments oriented perpendicular to the c-axis of the hexagonal nuclear structure. The magnetic saturation moment of iron is 2.2 μB at 4.2 K from neutron diffraction and 2.0 μB from magnetic measurements and decreases in a Brillouin-like manner on heating to TC=575 K. Above 450 K an increasing but reversible disorder of the nitrogen partial structure is observed. Y1 - 1999 SN - 1873-4669 VL - 288 IS - 1-2 SP - 79 EP - 87 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Hüning, Felix A1 - Leineweber, A. A1 - Jacobs, H. A1 - Lueken, H. T1 - Nitrogen Ordering and ferromagnetic properties of -Fe3N1+x (0.10  x  0.39) and -Fe3(N0.80C0.20)1.38 / Leineweber, A. ; Jacobs, H. ; Hüning, F. ; Lueken, H. ; Kockelmann, W. JF - Journal of Alloys and Compounds. 316 (2001), H. 1-2 Y1 - 2001 SN - 1873-4669 SP - 21 EP - 38 PB - - ER - TY - JOUR A1 - Hüning, Felix A1 - Jaekel, C. A1 - Francois, I. A1 - Kyas, G. T1 - Microwave surface impedance measurements on high-Tc superconductors / Jaekel, C. ; Francois, I. ; Kyas, G. ; Hüning, F. ; Roskos, H. G. ; Borghs, G. ; Kurz, H. JF - Czechoslovak Journal of Physics. 46 (1996), H. Suppl. 2 Y1 - 1996 SN - 1572-9486 IS - 46 SP - 1117 EP - 1118 PB - Springer Science+Business Media CY - Dordrecht ER - TY - JOUR A1 - Hüning, Felix A1 - Hillgärtner, Michael A1 - Reke, Michael T1 - Rolling Labs – Teaching Vehicle Electronics from the Beginning JF - International Journal of Engineering Pedagogy (iJEP) Y1 - 2019 U6 - https://doi.org/10.3991/ijep.v9i1.9241 SN - 2192-4880 VL - 9 IS - 1 SP - 34 EP - 49 ER - TY - JOUR A1 - Hüning, Felix A1 - Heuermann, Holger A1 - Wache, Franz-Josef A1 - Jajo, Rami Audisho T1 - A new wireless sensor interface using dual-mode radio JF - Journal of Sensors and Sensor Systems : JSSS N2 - The integration of sensors is one of the major tasks in embedded, control and “internet of things” (IoT) applications. For the integration mainly digital interfaces are used, starting from rather simple pulse-width modulation (PWM) interface to more complex interfaces like CAN (Controller Area Network). Even though these interfaces are tethered by definition, a wireless realization is highly welcome in many applications to reduce cable and connector cost, increase the flexibility and realize new emerging applications like wireless control systems. Currently used wireless solutions like Bluetooth, WirelessHART or IO-Link Wireless use dedicated communication standards and corresponding higher protocol layers to realize the wireless communication. Due to the complexity of the communication and the protocol handling, additional latency and jitter are introduced to the data communication that can meet the requirements for many applications. Even though tunnelling of other bus data like CAN data is generally also possible the latency and jitter prevent the tunnelling from being transparent for the bus system. Therefore a new basic technology based on dual-mode radio is used to realize a wireless communication on the physical layer only, enabling a reliable and real-time data transfer. As this system operates on the physical layer it is independent of any higher layers of the OSI (open systems interconnection) model. Hence it can be used for several different communication systems to replace the tethered physical layer. A prototype is developed and tested for real-time wireless PWM, SENT (single-edge nibble transmission) and CAN data transfer with very low latency and jitter. Y1 - 2018 U6 - https://doi.org/10.5194/jsss-7-507-2018 VL - Volume 7 IS - 2 SP - 507 EP - 515 PB - Copernicus Publ. CY - Göttingen ER - TY - JOUR A1 - Hüning, Felix A1 - Heuermann, Holger A1 - Wache, Franz-Josef T1 - Wireless CAN without WLAN or Bluetooth JF - CAN Newsletter N2 - In two developed concepts, dual-mode radio enables CAN participants to be integrated wirelessly into a CAN network. Constructed from a few components, a protocol-free, real-time transmission and thus transparent integration into CAN is provided. Y1 - 2018 IS - December 2018 SP - 44 EP - 46 ER - TY - JOUR A1 - Hüning, Felix A1 - Heuermann, Holger A1 - Wache, Franz-Josef T1 - Wireless CAN JF - Etz: Elektrotechnik & Automation N2 - In modernen elektronischen und mechatronischen Systemen, z. B. im industriellen oder automobil Bereich, kommunizieren eingebettete Steuergeräte und Sensoren vielfach über Bussysteme wie CAN oder LIN. Die Kommunikation findet in der Regel drahtgebunden statt, so dass der Kabelbaum für die Kommunikation sehr groß werden kann. Daher ist es naheliegend, Leitungen und dazugehörige Stecker, z. B. für nicht-sicherheitskritische Komfortsysteme, einzusparen und diese durch gerichtete Funkstrecken für kurze Entfernungen zu ersetzen. Somit könnten Komponenten wie ECUs oder Sensoren kabel- und steckerlos in ein Bussystem integriert werden. Zudem ist eine einfache galvanische und mechanische Trennung zu erreichen. Funkübertragung wird bei diesen Bussystemen derzeit nicht eingesetzt, da insbesondere die Echtzeitfähigkeit und die Robustheit der vorhandenen Funksysteme nicht den Anforderungen der Anwendungen entspricht. Zudem sind bestehende Funksysteme wie WLAN oder Bluetooth im Vergleich zur konventionellen Verkabelung teuer und es besteht hierbei die Möglichkeit, dass sie ausspioniert werden können und so sensible Daten entwendet werden können. In dieser Arbeit wird eine alternative Realisierung zu den bestehenden Funksystemen vorgestellt, die aus wenigen Komponenten aufzubauen ist. Es ist eine protokolllose, echtzeitfähige Übertragung möglich und somit die transparente Integration in ein Bussystem wie CAN. Y1 - 2018 SN - 0170-1711 VL - 139 IS - 10 SP - 22 EP - 26 PB - VDE-Verlag CY - Wuppertal ER - TY - JOUR A1 - Hüning, Felix A1 - Eifert, T. A1 - Lueken, H. A1 - Schmidt, P. T1 - High-temperature series expansion of the magnetic susceptibility of extended magnetic systems in a complete computer implementation / Eifert, T. ; Hüning, F. ; Lueken, H. ; Schmidt, P. ; Thiele, G. JF - Chemical Physics Letters. 364 (2002), H. 1-2 Y1 - 2002 SN - 0009-2614 SP - 69 EP - 74 PB - - ER - TY - JOUR A1 - Hüning, Felix A1 - Eifert, T. A1 - Handrick, K. A1 - Neuhausen, U. T1 - Computational Magnetochemistry: Complementary Quantum Mechanical Tools / Eifert, T. ; Handrick, K. ; Hüning, F. ; Neuhausen, U. ; Schilder, H. ; Lueken, H. JF - Zeitschrift für Anorganische und Allgemeine Chemie (ZAAC) - Journal of Inorganic and General Chemistry . 632 (2006), H. 4 Y1 - 2006 SN - 1521-3749 SP - 521 EP - 529 PB - - ER - TY - JOUR A1 - Hüning, Felix A1 - Eifert, T. A1 - Handrick, K. A1 - Neuhausen, U. T1 - Computational Magnetochemistry: Complementary Quantum Mechanical Tools / Eifert, T. ; Handrick, K. ; Hüning, F. ; Neuhausen, U. ; Schilder, H. ; Lueken, H. JF - 20 Jahre Wilhelm-Klemm-Stiftung / Kuratorium der Wilhelm-Klemm-Stiftung (Hrsg.) Y1 - 2006 SN - 978-3-8322-5520-6 SP - 193ff PB - Shaker CY - Aachen ER - TY - JOUR A1 - Hüning, Felix A1 - De Matteis, Stefan T1 - Entwicklung eines taktilen HMI für sehbehinderte und blinde Nutzerinnen und Nutzer JF - Blind - sehbehindert Y1 - 2020 SN - 0176-7836 VL - 140 IS - 2 SP - 9 EP - 19 PB - Edition Bentheim CY - Würzburg ER - TY - JOUR A1 - Hüning, Felix A1 - Backes, Andreas T1 - Direct observation of large Barkhausen jump in thin Vicalloy wires JF - IEEE Magnetics Letters Y1 - 2020 SN - 1949-307X U6 - https://doi.org/10.1109/LMAG.2020.3046411 VL - 11 IS - Art. 2506504 SP - 1 EP - 4 PB - IEEE CY - New York, NY ER - TY - JOUR A1 - Hüning, Felix T1 - Hart im Nehmen : Low-Voltage-Powermosfets mit Super-Junction-1-Technologie optimieren JF - Elektronik-Journal. 44 (2009), H. 12 Y1 - 2009 SN - 0013-5674 SP - 36 EP - 38 PB - - ER - TY - JOUR A1 - Hüning, Felix T1 - Die Anforderungen steigen : Entwicklungstrends bei MOSFETs für den Automobilbereich JF - Elektronik-Industrie. 39 (2008), H. 5 Y1 - 2008 SN - 0174-5522 SP - 74 EP - 76 PB - - ER - TY - JOUR A1 - Hüning, Felix T1 - Robusti affidabili per le Sfide dell’automotive JF - Selezione di Elettronica (2008) Y1 - 2008 SP - 116 EP - 117 PB - - ER - TY - JOUR A1 - Hüning, Felix T1 - Mosfet ottimizzati per l’automotive JF - Selezione di Elettronica (2009) Y1 - 2009 SP - 115 EP - 117 PB - - ER - TY - JOUR A1 - Hüning, Felix T1 - Entwicklungstrends bei MOSFETs für den Automobilbereich JF - Elektronik-Industrie . 39 (2008), H. 5 Y1 - 2008 SN - 0174-5522 SP - 74 EP - 76 PB - - ER - TY - JOUR A1 - Hüning, Felix T1 - SMD packages for PowerMOSFETs in automotive applications – developments and trends JF - Automotive Designline Europe (2009) Y1 - 2009 PB - - ER - TY - JOUR A1 - Hüning, Felix T1 - Using Trench PowerMOSFETs in Linear Mode JF - Power Electronics Europe (2012) N2 - If we think about applications for modern Power MOSFETs using trench technology, running them in linear mode may not be top of the priority list. Yet there are multiple uses for Trench Power MOSFETs in linear mode. In fact, even turning the device on and off in switching applications is a form of linear operation. Also, these components can be run in linear mode to protect the device against voltage surges. This article will illustrate the factors that need to be considered for linear operation and show how Trench Power MOSFETs are suited to it. Y1 - 2012 SN - 1748-3530 SP - 27 EP - 29 PB - DFA Media CY - Tonbridge ER - TY - JOUR A1 - Hüning, Felix T1 - PowerMOSFETs in ANL2-Technologie : Ansteuerungen bis in den kW-Bereich mit wenig Verlustleistung und Platzbedarf JF - Elektronik-Industrie Y1 - 2011 SN - 0174-5522 VL - 42 IS - 10 SP - 36 EP - 39 PB - Hüthig CY - Heidelberg ER - TY - JOUR A1 - Hüning, Felix T1 - Nachrüstmöglichkeiten von Dieselfahrzeugen aus technischer Sicht JF - Zeitschrift für Verkehrsrecht : NZV Y1 - 2019 IS - 1 SP - 27 EP - 32 PB - C.H.Beck ER - TY - JOUR A1 - Hüllenkremer, B. A1 - Glück, O. A1 - Emons, H. A1 - Lüth, H. A1 - Schöning, Michael Josef T1 - Voltohmmetrie an polykristallinen Goldelektroden JF - Gesellschaft Mess- und Automatisierungstechnik: Sensoren und Meßsysteme 2000 : Tagung Ludwigsburg, 13. und 14. März 2000 / VDI/VDE-Gesellschaft Meß- und Automatisierungstechnik Y1 - 2000 SN - 3-18-091530-7 N1 - VDI-Berichte; 1530 SP - 45 EP - 54 PB - VDI-Verl. CY - Düsseldorf: ER - TY - JOUR A1 - Höttges, Jörg A1 - Wallis, Steve G. A1 - Guymer, Ian T1 - Das ATZ-Modell zur Vorhersage des Schadstofftransports in Flüssen JF - Wasserwirtschaft. 82 (1992), H. 10 Y1 - 1992 SN - 0043-0978 SP - 494 EP - 497 ER - TY - JOUR A1 - Höttges, Jörg A1 - Ritterbach, E. A1 - Els, H. T1 - Optical Improvement of LDV-Measurement in Pipe Flow / Ritterbach, E.; J. Höttges; H. Els JF - Laser anemometry : advances and applications; proceedings of the 2. International Conference, Strathclyde, Scotland, 21st to 23rd September 1987 / ed. by John Turner ... UK LDA Users Group Y1 - 1987 SN - 3540187561 PB - Springer CY - Berlin [u.a.] ER - TY - JOUR A1 - Höttges, Jörg A1 - Koch, H.-G. A1 - Bosbach, R. T1 - Automatische Konstruktion von Teileinzugsgebieten für die Kanalnetzberechnung JF - Korrespondenz Abwasser : KA ; Informationsbl. für d. Abwasserwesen ; Wasser, Abwasser, Abfall / Gesellschaft zur Förderung der Abwassertechnik. 42 (1995), H. 12 Y1 - 1995 SN - 0341-1478 ER - TY - JOUR A1 - Höttges, Jörg A1 - Feldhaus, R. A1 - Brockhaus, T. A1 - Rouvé, Gerhard T1 - Finite Element Simulation of Flow and Pollution Transport applied to a Part of the River Rhine / Feldhaus, R.; J. Höttges, T. Brockhaus; G. Rouvé JF - Hydraulic and environmental modelling : proceedings of the Second International Conference on Hydraulic and Environmental Modelling of Coastal, Estuarine, and River Waters / [IAHR-AIRH]. Ed. by R. A. Falconer Y1 - 1992 N1 - International Conference on Hydraulic and Environmental Modelling of Coastal, Estuarine, and River Waters ; (2, 1992, Bradford) PB - Ashgate CY - Aldershot, Hants, UK [u.a.] ER - TY - JOUR A1 - Höttges, Jörg A1 - Bosbach, Ralf T1 - Einsatz moderner Methoden in der Kanalnetzplanung JF - Abwassertechnik - Abfalltechnik und Recycling. awt. 47 (1996), H. 6 Y1 - 1996 SN - 0932-3708 SP - 45 EP - 47 ER - TY - JOUR A1 - Höttges, Jörg A1 - Arnold, Uwe A1 - Rouvé, Gerhard T1 - Profiles of Mixing Coefficient in Compound Open Channel JF - Flow modeling and turbulence measurements : [... a collection of lectures and papers presented at the Fourth International Symposium on Refined Flow Modelling and Turbulence Measurements held in Wuhan, People's Republic of China, on September 20-23, 1990] Y1 - 1992 SN - 1-56032-209-8 N1 - International Symposium on Refined Flow Modelling and Turbulence Measurements <4, 1990, Wuhan> PB - Hemisphere Publ. Corp. CY - Washington, DC [u.a.] ER - TY - JOUR A1 - Höttges, Jörg A1 - Arnold, Uwe A1 - Rouvé, Gerhard T1 - Grundlagenuntersuchungen zur Schadstoffausbreitung in Flüssen JF - Schadstofftransport in Grund- und Oberflächengewässern / Rouvé, Gerhard [Hrsg.] Y1 - 1991 N1 - Mitteilungen / Institut für Wasserbau und Wasserwirtschaft, Rheinisch-Westfälische Technische Hochschule Aachen ; 81; Wasserbau-Seminar <21, 1991, Aachen> CY - Aachen ER - TY - JOUR A1 - Höttges, Jörg A1 - Arnold, Uwe A1 - Rouvé, Gerhard T1 - Measurement of transverse mixing using digital image acquisition JF - Mixing and transport in the environment : a memorial volume for Catherine M. Allen (1954-1991) / ed. by Keith J. Beven Y1 - 1994 SN - 0471941425 PB - Wiley CY - Chichester [u.a.] ER - TY - JOUR A1 - Höttges, Jörg A1 - Arnold, Uwe A1 - Rouvé, Gerhard T1 - Flüsse und Bäche brauchen ein breiteres Bett. Naturnahe Umgestaltung der Fliessgewässer / Arnold, Uwe; Höttges, Jörg; Rouvé, Gerhard JF - Forschung. Mitteilungen der DFG (1988) Y1 - 1988 SN - 0172-1518 SP - 17 EP - 20 ER - TY - JOUR A1 - Höttges, Jörg A1 - Arnold, Uwe A1 - Rouvé, Gerhard T1 - Combined Digital Image and Finite Element Analysis of Mixing in Compound Open Channel Flow / Arnold, U.; J. Höttges; G. Rouvé JF - Refined flow modelling and turbulence measurements : proceedings of the Third International Symposium Tokyo, Japan 26 - 28 July, 1988 / ed. by Y. Iwasa. Scientific Organizing Committee of the Third International Symposium on Refined Flow Modelling and Tur Y1 - 1989 SN - 4-946443-03-7 N1 - International Symposium on Refined Flow Modelling and Turbulence Measurements <3, 1988, Tōkyō> SP - 569 EP - 576 PB - Universal Acad. Press CY - Tokyo ER - TY - JOUR A1 - Höttges, Jörg T1 - Turbulence and Mixing Mechanics in Compound Open Channel Flow / Arnold, Uwe; Höttges, Jörg; Rouvé, Gerhard JF - On cutoff ratios of curved channels : paper presented at the 23rd Congress of the IAHR, Ottawa, Canada, August 21 - 25, 1989 / G. J. Klaassen; B. H. J.van Zanten Y1 - 1990 N1 - Congress of the IAHR ; (23 : ; 1989.08.21-25 : ; Ottawa) PB - Delft Hydraulics CY - Delft ER - TY - JOUR A1 - Höttges, Jörg T1 - A Full Finite Element Solution for the Unsteady Advection-Diffusion Equation JF - Computational methods in water resources : [proceedings of the Ninth International Conference on Computational Methods in Water Resources held at the University of Colorado at Denver, U.S.A., in June 1992] / ed.: T. F. Russell Y1 - 1992 SN - 185312169X N1 - International Conference on Computational Methods in Water Resources ; (9, 1992, Denver, Colo.) PB - Computational Mechanics Publications [u.a.] CY - Southampton [u.a.] ER - TY - JOUR A1 - Höttges, Jörg T1 - Verschiedene Verfahren zur Ermittlung der angeschlossenen Flächen – Auswirkungen auf Qualität und Quantität JF - 6. Kölner Kanal-Kolloquium : 07. und 08. September 2005 im Maternushaus, Köln / hrsg. von J. Pinnekamp ... Y1 - 2005 SN - 3-932-590-98-8 N1 - Kölner Kanal Kolloquium <6, 2005, Köln> ; Aachener Schriften zur Stadtentwässerung ; 6 PB - Ges. zur Förderung der Siedlungswasserwirtschaft an der RWTH Aachen e.V. CY - Aachen ER - TY - JOUR A1 - Höttges, Jörg T1 - QKan - Management of drainage system data with QGIS JF - Free and Open Source Software for Geospatial (FOSS4G) Conference Proceedings Y1 - 2017 VL - 17 IS - Article 13 SP - 95 EP - 100 ER - TY - JOUR A1 - Hötter, Jan-Steffen A1 - Fateri, Miranda A1 - Gebhardt, Andreas T1 - Prozessoptimierung des SLM-Prozesses mit hoch-reflektiven und thermisch sehr gut leitenden Materialien durch systematische Parameterfindung und begleitende Simulationen am Beispiel von Silber JF - RTejournal - Forum für Rapid Technologie N2 - Additive Manufacturing durch Aufschmelzen von Metallpulvern hat sich auf breiter Front als Herstellverfahren, auch für Endprodukte, etabliert. Besonders für die Variante des Selective Laser Melting (SLM) sind Anwendungen in der Zahntechnik bereits weit verbreitet und der Einsatz in sensitiven Branchen wie der Luftfahrt ist in greifbare Nähe gerückt. Deshalb werden auch vermehrt Anstrengungen unternommen, um bisher nicht verarbeitete Materialien zu qualifizieren. Dies sind vorzugsweise Nicht-Eisen- und Edelmetalle, die sowohl eine sehr hohe Reflektivität als auch eine sehr gute Wärmeleitfähigkeit aufweisen – beides Eigenschaften, die die Beherrschung des Laser-Schmelzprozesses erschweren und nur kleine Prozessfenster zulassen. Die Arbeitsgruppe SLM des Lehr- und Forschungsgebietes Hochleistungsverfahren der Fertigungstechnik hat sich unter der Randbedingung einer kleinen und mit geringer Laserleistung ausgestatteten SLM Maschine der Aufgabe gewidmet und am Beispiel von Silber die Parameterfelder für Einzelspuren und wenig komplexe Geometrien systematisch untersucht. Die Arbeiten wurden von FEM Simulationen begleitet und durch metallographische Untersuchungen verifiziert. Die Ergebnisse bilden die Grundlage zur schnellen Parameterfindung bei komplexen Geometrien und bei Veränderungen der Zusammensetzung, wie sie bei zukünftigen Legierungen zu erwarten sind. Die Ergebnisse werden exemplarisch auf unterschiedliche Geometrien angewandt und entsprechende Bauteile gezeigt. N2 - Additive manufacturing by melting of metal powders is a method that has been established even for the manufacturing of final products. In particular, Selective Laser Melting (SLM) is currently applied for prosthetic dentistry. In the near future, this technology will access sensitive industries like aerospace engineering. This leads to the need to process new materials. Therefore, especially non-ferrous metals and noble metals must be determined and qualified. These materials have in common a very high reflectivity and an excellent thermal conductivity. In general, these two properties counteract the control of the melt pool and contribute to very narrow process windows. The “SLM” research team of the Aachen University of Applied Science, AcUAS (FH Aachen) systematically investigated process parameter fields for silver. The work focused on a small SLM desktop machine with comparably low laser power. The results are verified using FEA and metallographic inspections and will support future set-ups for complex geometries. Furthermore, the obtained parameter fields are applied to make different geometric objects and to manufactured parts, which are presented. KW - SLM KW - Selektives Laser Schmelzen KW - Silber Y1 - 2012 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0009-2-33639 SN - 1614-0923 VL - 9 IS - 1 SP - 1 EP - 14 PB - Fachhoschule Aachen CY - Aachen ER - TY - JOUR A1 - Hötter, Jan-Steffen A1 - Fateri, Miranda A1 - Gebhardt, Andreas T1 - Selective laser melting of metals: desktop machines open up new chances even for small companies JF - Advanced materials research N2 - Additive manufacturing (AM) of metal parts by using Selective Laser Melting (SLM) has become a powerful tool mostly in the area of automotive, aerospace engineering and others. Especially in the field of dentistry, jewelry and related branches that require individualized or even one-of-a-kind products, the direct digital manufacturing process opens up new ways of design and manufacturing. In these fields, mostly small and medium sized businesses (SME) are operating which do not have sufficient human and economic resources to invest in this technology. But to stay competitive, the application of AM can be regarded as a necessity. In this situation a new desktop machine (Realizer SLM 50) was introduced that cost about 1/3 of a shop floor SLM machine and promises small quality parts. To find out whether the machine really is an alternative for SMEs the University of Applied Science, Aachen, Germany, designed, build and optimized typical parts from the dentistry and the jewelry branches using CoCr and silver material, the latter being new with this application. The paper describes the SLM procedure and how to find and optimize the most important parameters. The test is accompanied by digital simulation in order to verify the build parameters and to plan future builds. The procedure is shown as well as the resulting parts made from CoCr and silver material. Y1 - 2012 U6 - https://doi.org/10.4028/www.scientific.net/AMR.622-623.461 SN - 1662-8985 (E-Journal); 1022-6680 (Print) VL - 622-623 SP - 461 EP - 465 PB - Trans Tech Publ. CY - Baech ER - TY - JOUR A1 - Hörenbaum, Christoph A1 - Laumann, Jörg A1 - Prokop, Ines T1 - Zur Anwendung des Eurocode 3 Teil 1-2 für die Heißbemessung und Anregungen für dessen Novellierung JF - Stahlbau N2 - Die Eurocodes werden bis zum Jahr 2020 im Europäischen Komitee für Normung (CEN), Technisches Komitee TC 250, überarbeitet. In Vorbereitung auf die Eurocode-Novellierung haben engagierte Ingenieure im Rahmen der Initiative PraxisRegeln Bau (PRB) die für die praktische Anwendung häufig genutzten Teile des Eurocode 3 untersucht. Mit dem Ziel, die Praxistauglichkeit des Eurocode 3 für die Heißbemessung zu verbessern, wurden die bestehende Norm EN 1993 Teil 1-2 insbesondere in Bezug auf die Anwenderfreundlichkeit analysiert und Vorschläge für die europäische Novellierung erarbeitet. Die Analysen zeigen, dass durch Umstrukturierungen und durch die Einführung von Tabellen die Verständlichkeit und Anwenderfreundlichkeit der Regeln für die Heißbemessung bedeutend erhöht werden können. KW - EN 1993-1-2 KW - Tragwerksbemessung KW - Brandfall KW - Forschung, pränormativ KW - structural design Y1 - 2016 U6 - https://doi.org/10.1002/stab.201610382 SN - 1437-1049 VL - 85 IS - 6 SP - 429 EP - 434 PB - Ernst & Sohn GmbH CY - Berlin ER - TY - JOUR A1 - Höhne, Tim A1 - Pulz, Christian ED - Isensee, Johannes T1 - Projekt Adaptive Logistik : Dienstleister für die Montage in der Auftragsfertigung JF - RFID-Innovationen in Produktion und Logistik - Eine Analyse zu Potenzialen des RFID-Einsatzes in Produktion und Logistik Y1 - 2009 SN - 1860-840X N1 - Durchgeführt im Rahmen des BMBF-Rahmenprogramms Forschung für die Produktion von Morgen / IPRI International Performance Research Institute ; Research paper / IPRI ; 20 SP - 11 EP - 19 ER - TY - JOUR A1 - Hunker, Jan L. A1 - Gossmann, Matthias A1 - Raman, Aravind Hariharan A1 - Linder, Peter T1 - Artificial neural networks in cardiac safety assessment: Classification of chemotherapeutic compound effects on hiPSC-derived cardiomyocyte contractility JF - Journal of Pharmacological and Toxicological Methods Y1 - 2021 U6 - https://doi.org/10.1016/j.vascn.2021.107044 SN - 1056-8719 VL - 111 IS - Article number 107044 PB - Elsevier CY - New York ER - TY - JOUR A1 - Hulsebosch, R. J. A1 - Günther, C. A1 - Horn, C. A1 - Holtmanns, S. A1 - Howker, K. A1 - Paterson, K. A1 - Claessens, J. A1 - Schuba, Marko ED - Mitchell, Chris J. T1 - Pioneering Advanced Mobile Privacy and Security JF - Security for mobility Y1 - 2004 SN - 9781849190886 U6 - https://doi.org/10.1049/PBTE051E_ch N1 - IEE telecommunications series ; 51 SP - 383 EP - 432 PB - Institution of Electrical Engineers CY - London ER - TY - JOUR A1 - Hugenroth, Kristin A1 - Neidlin, Michael A1 - Engelmann, Ulrich M. A1 - Kaufmann, Tim A. S. A1 - Steinseifer, Ulrich A1 - Heilmann, Torsten T1 - Tipless Transseptal Cannula Concept Combines Improved Hemodynamic Properties and Risk‐Reduced Placement: an In Silico Proof‐of‐Concept JF - Artificial Organs Y1 - 2021 U6 - https://doi.org/10.1111/aor.13964 SN - 1525-1594 IS - Accepted Article PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Hugenroth, Kristin A1 - Borchardt, Ralf A1 - Ritter, Philine A1 - Groß‑Hardt, Sascha A1 - Meyns, Bart A1 - Verbelen, Tom A1 - Steinseifer, Ulrich A1 - Kaufmann, Tim A. S. A1 - Engelmann, Ulrich M. T1 - Optimizing cerebral perfusion and hemodynamics during cardiopulmonary bypass through cannula design combining in silico, in vitro and in vivo input JF - Scientific Reports N2 - Cardiopulmonary bypass (CPB) is a standard technique for cardiac surgery, but comes with the risk of severe neurological complications (e.g. stroke) caused by embolisms and/or reduced cerebral perfusion. We report on an aortic cannula prototype design (optiCAN) with helical outflow and jet-splitting dispersion tip that could reduce the risk of embolic events and restores cerebral perfusion to 97.5% of physiological flow during CPB in vivo, whereas a commercial curved-tip cannula yields 74.6%. In further in vitro comparison, pressure loss and hemolysis parameters of optiCAN remain unaffected. Results are reproducibly confirmed in silico for an exemplary human aortic anatomy via computational fluid dynamics (CFD) simulations. Based on CFD simulations, we firstly show that optiCAN design improves aortic root washout, which reduces the risk of thromboembolism. Secondly, we identify regions of the aortic intima with increased risk of plaque release by correlating areas of enhanced plaque growth and high wall shear stresses (WSS). From this we propose another easy-to-manufacture cannula design (opti2CAN) that decreases areas burdened by high WSS, while preserving physiological cerebral flow and favorable hemodynamics. With this novel cannula design, we propose a cannulation option to reduce neurological complications and the prevalence of stroke in high-risk patients after CPB. Y1 - 2021 U6 - https://doi.org/10.1038/s41598-021-96397-2 SN - 2045-2322 VL - 11 IS - Art. No. 16800 SP - 1 EP - 12 PB - Springer CY - Berlin ER - TY - JOUR A1 - Huck, Christina A1 - Schiffels, Johannes A1 - Herrera, Cony N. A1 - Schelden, Maximilian A1 - Selmer, Thorsten A1 - Poghossian, Arshak A1 - Baumann, Marcus A1 - Wagner, Patrick A1 - Schöning, Michael Josef T1 - Metabolic responses of Escherichia coli upon glucose pulses captured by a capacitive field-effect sensor JF - Physica Status Solidi (A) N2 - Living cells are complex biological systems transforming metabolites taken up from the surrounding medium. Monitoring the responses of such cells to certain substrate concentrations is a challenging task and offers possibilities to gain insight into the vitality of a community influenced by the growth environment. Cell-based sensors represent a promising platform for monitoring the metabolic activity and thus, the “welfare” of relevant organisms. In the present study, metabolic responses of the model bacterium Escherichia coli in suspension, layered onto a capacitive field-effect structure, were examined to pulses of glucose in the concentration range between 0.05 and 2 mM. It was found that acidification of the surrounding medium takes place immediately after glucose addition and follows Michaelis–Menten kinetic behavior as a function of the glucose concentration. In future, the presented setup can, therefore, be used to study substrate specificities on the enzymatic level and may as well be used to perform investigations of more complex metabolic responses. Conclusions and perspectives highlighting this system are discussed. Y1 - 2013 U6 - https://doi.org/10.1002/pssa.201200900 SN - 0031-8965 VL - 210 IS - 5 SP - 926 EP - 931 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Huck, Christina A1 - Poghossian, Arshak A1 - Wagner, Patrick A1 - Schöning, Michael Josef T1 - Combined amperometric/field-effect sensor for the detection of dissolved hydrogen JF - Sensors and actuators B: Chemical N2 - Real-time and reliable monitoring of the biogas process is crucial for a stable and efficient operation of biogas production in order to avoid digester breakdowns. The concentration of dissolved hydrogen (H₂) represents one of the key parameters for biogas process control. In this work, a one-chip integrated combined amperometric/field-effect sensor for monitoring the dissolved H₂ concentration has been developed for biogas applications. The combination of two different transducer principles might allow a more accurate and reliable measurement of dissolved H₂ as an early warning indicator of digester failures. The feasibility of the approach has been demonstrated by simultaneous amperometric/field-effect measurements of dissolved H₂ concentrations in electrolyte solutions. Both, the amperometric and the field-effect transducer show a linear response behaviour in the H₂ concentration range from 0.1 to 3% (v/v) with a slope of 198.4 ± 13.7 nA/% (v/v) and 14.9 ± 0.5 mV/% (v/v), respectively. Y1 - 2012 U6 - https://doi.org/10.1016/j.snb.2012.10.050 SN - 0925-4005 N1 - Part of special issue "Selected Papers from the 14th International Meeting on Chemical Sensors" VL - 187 SP - 168 EP - 173 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Huck, Christina A1 - Poghossian, Arshak A1 - Kerroumi, Iman A1 - Schusser, Sebastian A1 - Bäcker, Matthias A1 - Zander, Willi A1 - Schubert, Jürgen A1 - Buniatyan, Vahe V. A1 - Martirosyan, Norayr W. A1 - Wagner, Patrick A1 - Schöning, Michael Josef T1 - Multiparameter sensor chip with Barium Strontium Titanate as multipurpose material JF - Electroanalysis N2 - It is well known that biochemical and biotechnological processes are strongly dependent and affected by a variety of physico-chemical parameters such as pH value, temperature, pressure and electrolyte conductivity. Therefore, these quantities have to be monitored or controlled in order to guarantee a stable process operation, optimization and high yield. In this work, a sensor chip for the multiparameter detection of three physico-chemical parameters such as electrolyte conductivity, pH and temperature is realized using barium strontium titanate (BST) as multipurpose material. The chip integrates a capacitively coupled four-electrode electrolyte-conductivity sensor, a capacitive field-effect pH sensor and a thin-film Pt-temperature sensor. Due to the multifunctional properties of BST, it is utilized as final outermost coating layer of the processed sensor chip and serves as passivation and protection layer as well as pH-sensitive transducer material at the same time. The results of testing of the individual sensors of the developed multiparameter sensor chip are presented. In addition, a quasi-simultaneous multiparameter characterization of the sensor chip in buffer solutions with different pH value and electrolyte conductivity is performed. To study the sensor behavior and the suitability of BST as multifunctional material under harsh environmental conditions, the sensor chip was exemplarily tested in a biogas digestate. Y1 - 2014 U6 - https://doi.org/10.1002/elan.201400076 SN - 1521-4109 (E-Journal); 1040-0397 (Print) VL - 26 IS - 5 SP - 980 EP - 987 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Huck, Christina A1 - Poghossian, Arshak A1 - Bäcker, Matthias A1 - Reisert, Steffen A1 - Schubert, J. A1 - Zander, W. A1 - Begoyan, V. K. A1 - Buniatyan, V. V. A1 - Schöning, Michael Josef T1 - Chemical sensors based on a high-k perovskite oxide of barium strontium titanate JF - Procedia Engineering N2 - High-k perovskite oxide of barium strontium titanate (BST) represents a very attractive multi-functional transducer material for the development of (bio-)chemical sensors for liquids. In this work, BST films have been applied as a sensitive transducer material for a label-free detection of adsorbed charged macromolecules (positively charged polyelectrolytes) and concentration of hydrogen peroxide vapor as well as protection insulator layer for a contactless electrolyte-conductivity sensor. The experimental results of characterization of individual sensors are presented. Special emphasis is devoted towards the development of a capacitively-coupled contactless electrolyte-conductivity sensor. KW - barium strontium titanate KW - high-k material KW - contactless conductivity sensor KW - multi-functional material KW - hydrogen peroxide Y1 - 2014 U6 - https://doi.org/10.1016/j.proeng.2014.11.258 SN - 1877-7058 N1 - EUROSENSORS 2014 ; European Conference on Solid-State Transducers <28, 2014> VL - 87 SP - 28 EP - 31 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Huck, Christina A1 - Poghossian, Arshak A1 - Bäcker, Matthias A1 - Reisert, Steffen A1 - Kramer, Friederike A1 - Begoyan, Vardges K. A1 - Buniatyan, Vahe V. A1 - Schöning, Michael Josef T1 - Multi-parameter sensing using high-k oxide of barium strontium titanate JF - Physica status solidi (a) N2 - High-k perovskite oxide of barium strontium titanate (BST) represents a very attractive multi-functional transducer material for the development of (bio-)chemical sensors. In this work, a Si-based sensor chip containing Pt interdigitated electrodes covered with a thin BST layer (485 nm) has been developed for multi-parameter chemical sensing. The chip has been applied for the contactless measurement of the electrolyte conductivity, the detection of adsorbed charged macromolecules (positively charged polyelectrolytes of polyethylenimine) and the concentration of hydrogen peroxide (H2O2) vapor. The experimental results of functional testing of individual sensors are presented. The mechanism of the BST sensitivity to charged polyelectrolytes and H2O2 vapor has been proposed and discussed. Y1 - 2015 U6 - https://doi.org/10.1002/pssa.201431911 SN - 1862-6319 VL - 212 IS - 6 SP - 1259 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Huck, Christina A1 - Poghossian, Arshak A1 - Bäcker, Matthias A1 - Chaudhuri, S. A1 - Zander, W. A1 - Schubert, J. A1 - Begoyan, V. K. A1 - Buniatyan, V. V. A1 - Wagner, P. A1 - Schöning, Michael Josef T1 - Capacitively coupled electrolyte-conductivity sensor based on high-k material of barium strontium titanate JF - Sensors and actuators. B: Chemical Y1 - 2014 U6 - https://doi.org/10.1016/j.snb.2014.02.103 SN - 1873-3077 (E-Journal); 0925-4005 (Print) IS - 198 SP - 102 EP - 109 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Huck, Christina A1 - Jolly, Christina A1 - Wagner, Patrick A1 - Poghossian, Arshak A1 - Schöning, Michael Josef T1 - One-chip integrated dual amperometric/field-effect sensor for the detection of dissolved hydrogen JF - Procedia Engineering. 25 (2011) Y1 - 2011 SN - 1877-7058 N1 - EurosensorsXXV ; Proc. Eurosensors XXV, September 4-7, 2011, Athens, Greece SP - 1161 EP - 1164 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Huber, M. A1 - Streblow, R. A1 - Müller, D. A1 - Lange, S. A1 - Joneleit, R. A1 - Sefker, T. A1 - Rau, Sebastian A1 - Wollert, Jörg T1 - Funksignalübertragung in Luftleitungen JF - HLH : Lüftung, Klima, Heizung, Sanitär, Gebäudetechnik Y1 - 2014 SN - 1436-5103 VL - Bd. 65 IS - H. 7/8 SP - 36 EP - 40 ER - TY - JOUR A1 - Hoyler, Friedrich A1 - White, D.H. A1 - Hoff, R. W. T1 - Nuclear structure of 241Pu from neutron-capture, (d,p)-, and (d,t)-reaction measurements / D. H. White ; R. W. Hoff ... F. Hoyler ... JF - Physical review / C. 57 (1998), H. 3 Y1 - 1998 SN - 0556-2813 SP - 1112 EP - 1133 ER - TY - JOUR A1 - Hoyler, Friedrich A1 - Shi, Z. R. A1 - Schreckenback, K. A1 - Aprahamian, A. T1 - Complete spectroscopy and the 162Dy nucleus / Z. R. Shi ; K. Schreckenbach ; A. Aprahamian ... F. Hoyler ... JF - AIP conference proceedings (1999) Y1 - 1999 SN - 0094-243X N1 - American Institute of Physics conference proceedings SP - 237 EP - 238 ER - TY - JOUR A1 - Hoyler, Friedrich A1 - Prokofjevs, P. A1 - Bondarenko, V. T1 - Study of nuclear structure of 164Dy in (n, gamma) and(n, n' gamma) reactions / P. Prokofjevs ; V. Bondarenko ; F. Hoyler ... Y1 - 1997 SN - 1122-1437 N1 - Conference proceedings - Italian Physical Society SP - 759 ER - TY - JOUR A1 - Hoyler, Friedrich A1 - Petkov, P. A1 - Andrejtscheff, W. T1 - Absolute E0, E1 and E2 transition rates in even-even nuclei obtained in thermal neutron capture / P. Petkov ; W. Andrejtscheff ... F. Hoyler ... JF - Journal of Physics G. 14 (1988), H. S Y1 - 1988 SN - 0305-4616 SP - S97 EP - S102 ER - TY - JOUR A1 - Hoyler, Friedrich A1 - Mohr, P. A1 - Staudt, G. T1 - Alpha-cluster states of 212po in a realistic potential model JF - Physical review / C. 50 (1994), H. 5 Y1 - 1994 SN - 0556-2813 SP - 2631 EP - 2634 ER - TY - JOUR A1 - Hoyler, Friedrich A1 - Kessler, E. G. A1 - Greene, G. L. T1 - High accuracy, absolute wavelength determination of capture gamma-ray energies for E≤5 MeV and the direct determination of binding energies in light nuclei / E.G. Kessler ; G. L. Greene ... F. Hoyler JF - Journal of Physics G. 14 (1988), H. S Y1 - 1988 SN - 0305-4616 SP - S167 EP - S174 ER - TY - JOUR A1 - Hoyler, Friedrich A1 - Hoff, R. W. A1 - Börner, H. G. T1 - Nuclear structure of 170Tm from neutron-capture and (d,p)-reaction measurements / R. W. Hoff ; H. G. Börner ... F. Hoyler ... JF - Physical review / C. 54 (1996), H. 1 Y1 - 1996 SN - 0556-2813 SP - 78 EP - 116 ER - TY - JOUR A1 - Hoyler, Friedrich A1 - Hamada, S. A. A1 - Hamilton, W. D. T1 - Gamma-gamma directional correlation measurements in 84Kr following thermal neutron capture by natural krypton / S. A. Hamada ; W. D. Hamilton ; F. Hoyler JF - Journal of physics / G. 13 (1987), H. 9 Y1 - 1987 SN - 0305-4616 SP - 1143 EP - 1163 ER - TY - JOUR A1 - Hoyler, Friedrich A1 - Drissi, S. A1 - Tercier, P. A. T1 - The 112Cd laboratory - An extension : EO strengths, multiphonon states and coupled vibrations / S. Drissi ; P. A. Tercier ... F. Hoyler ... JF - Nuclear physics / A. 614 (1997), H. 2 Y1 - 1997 SN - 0375-9474 SP - 137 EP - 182 ER - TY - JOUR A1 - Hoyler, Friedrich A1 - Corminboeuf, F. A1 - Jolie, J. T1 - Kp=4+ double-gvibration in 164Dy / F. Corminboeuf ; J. Jolie ... F. Hoyler ... JF - Physical review / C. 56 (1997), H. 3 Y1 - 1997 SN - 0556-2813 SP - R1201 ER - TY - JOUR A1 - Hoyler, Friedrich A1 - Colvin, G. G. A1 - Robinson, S. J. T1 - 100Ru studied by thermal neutron capture / G. G. Colvin ; S. J. Robinson ; F. Hoyler JF - Journal of Physics G. 14 (1988), H. 11 Y1 - 1988 SN - 0305-4616 SP - 1411 EP - 1421 ER - TY - JOUR A1 - Hoyler, Friedrich A1 - Colvin, G. G. A1 - Robinson, S. J. T1 - E0 transitions in 106Pd studied by neutron capture / G. G. Colvin ; F. Hoyler ; S. J. Robinson JF - Journal of physics / G. 13 (1987), H. 2 Y1 - 1987 SN - 0305-4616 SP - 191 EP - 204 ER - TY - JOUR A1 - Hoyler, Friedrich A1 - Collins, S. P. A1 - Eid, S. A. T1 - A search for mixed-symmetry states in the mass A approximately 50 region / S. P. Collins ; S. A. Eid ... F. Hoyler JF - Journal of Physics G. 15 (1989), H. 3 Y1 - 1989 SN - 0954-3899 SP - 321 EP - 332 ER - TY - JOUR A1 - Hoyler, Friedrich A1 - Cizewski, J. A. A1 - Colvin, G. G. T1 - Neutron capture on 193Ir and σ<σ SUB>max states in 195Ir / J. A. Cizewski ; G. G. Colvin ... F. Hoyler ... JF - Journal of Physics G. 14 (1988), H. S Y1 - 1988 SN - 0305-4616 SP - S103 EP - S108 ER - TY - JOUR A1 - Hoyler, Friedrich A1 - Cata-Danil, G. A1 - Guazzoni, P. T1 - (p,t) transition strengths for nuclei around Z = 50 and the IBA model / G. Cata-Danil ; P. Guazzoni ... F. Hoyler ... JF - Journal of physics / G. 22 (1996), H. 1 Y1 - 1996 SN - 0305-4616 SP - 107 EP - 114 ER - TY - JOUR A1 - Hoyler, Friedrich A1 - Börner, H. G. A1 - Robinson, S. T1 - Recent developments at the ILL (n,γ)-facility JF - Journal of Physics G. 14 (1988), H. S Y1 - 1988 SN - 0305-4616 SP - S161 EP - S165 ER - TY - JOUR A1 - Hoyler, Friedrich A1 - Bauske, I. A1 - Arias, J. M. T1 - First observation of scissors mode states in an odd-mass nucleus / I. Bauske ; J. M. Arias ... F. Hoyler ... JF - Physical review letters. 71 (1993), H. 7 Y1 - 1993 SN - 0031-9007 SP - 975 EP - 978 ER - TY - JOUR A1 - Hoyler, Friedrich A1 - Balodis, M. A1 - Prokofjevs, P. T1 - Level scheme of 194Ir / M. Balodis ; P. Prokofjevs ... F. Hoyler ... JF - Nuclear physics / A. 641 (1998), H. 2 Y1 - 1998 SN - 0375-9474 SP - 133 EP - 187 ER - TY - JOUR A1 - Hoyler, Friedrich A1 - Aprahamian, A. A1 - Wu, X. A1 - Lesher, S. R. T1 - Complete spectroscopy of the 162Dy nucleus / Aprahamian, A. ; Wu, X. ; Lesher, S. R. ; Warner, D. D. ; Gelletly, W. ; Börner, H. G. ; Hoyler, F. ; Schreckenbach, K. ; Carsten R. F. ; Shi, Z. R. ; Kusnezov, D. ; Ibrahim, M. ; Macchiavelli, A. O. ; Brinkman JF - Nuclear physics / A. 764 (2006) Y1 - 2006 SN - 0375-9474 SP - 42 EP - 78 ER - TY - JOUR A1 - Hoyler, Friedrich A1 - Andrejtscheff, W. A1 - Petkov, P. T1 - A mixed symmetry or quasineutron pair interpretation of the Kpi =03+ level in 172Yb / W. Andrejtscheff ; P. Petkov ... F. Hoyler JF - Journal of physics / G. 12 (1986), H. 6 Y1 - 1986 SN - 0305-4616 SP - L151 EP - L156 ER - TY - JOUR A1 - Hoyler, Friedrich T1 - Microscopic and semimicroscopic analysis of the reaction 27al- (p,#ga)24mg in the energy range between 20 and 45 mev JF - Physical review / C, nuclear physics. 31 (1985), H. 1 Y1 - 1985 SN - 0556-2813 SP - 17 ER - TY - JOUR A1 - Hough, Lindsay B. A1 - Nalwalk, Julia W. A1 - Ding, Xinxin A1 - Scheer, Nico T1 - Opioid Analgesia in P450 Gene Cluster Knockout Mice: A Search for Analgesia-Relevant Isoforms JF - Drug Metabolism and Disposition Y1 - 2015 U6 - https://doi.org/10.1124/dmd.115.065490 SN - 1521-009x VL - 43 IS - 9 SP - 1326 EP - 1330 ER - TY - JOUR A1 - Hoskens, R.C.P. A1 - Roer, T.G. van de A1 - Tolstikhin, V.I. A1 - Förster, Arnold T1 - Hot electron injection laser: vertically integrated transistor-laser structure for high-speed, low-chirp direct modulation JF - LEOS 2000 : 2000 IEEE annual meeting conference proceedings; 13th annual meeting; IEEE Lasers and Electro-Optics Society 2000 annual meeting; 13-16 November 2000, The Westin Rio Mar Beach, Rio Grande, Puerto Rico. Vol. 2 Y1 - 2000 SN - 0-7803-5947-X N1 - 2000 IEEE LEOS annual meeting SP - 444 EP - 445 PB - IEEE Service Center CY - Piscataway, NJ ER - TY - JOUR A1 - Hoskens, R. C. P. A1 - Tolstikhin, V.I. A1 - Förster, Arnold A1 - Roer, T.G. van de T1 - Vertically integrated transistor-laser structure, take 2 JF - WOCSDICE 2000, 24th Workshop on Compound Semiconductor Devices and Integrated Circuits held in Europe : May 29 - June 02, 2000, Aegean Sea, Greece. Y1 - 2000 SN - 0970311109 N1 - WOCSDICE ; (24, 2000) Workshop on Compound Semiconductor Devices and Integrated Circuits held in Europe ; (24 : ; 2000.05.29-06.02) PB - Univ. of Michigan CY - Ann Arbor, Mich. ER - TY - JOUR A1 - Horstmann, Marie-Therese A1 - Bialonski, Stephan A1 - Noenning, Nina A1 - Mai, Heinke A1 - Prusseit, Jens A1 - Wellmer, Jörg A1 - Hinrichs, Hermann A1 - Lehnertz, Klaus T1 - State dependent properties of epileptic brain networks: Comparative graph–theoretical analyses of simultaneously recorded EEG and MEG JF - Clinical Neurophysiology N2 - Objective To investigate whether functional brain networks of epilepsy patients treated with antiepileptic medication differ from networks of healthy controls even during the seizure-free interval. Methods We applied different rules to construct binary and weighted networks from EEG and MEG data recorded under a resting-state eyes-open and eyes-closed condition from 21 epilepsy patients and 23 healthy controls. The average shortest path length and the clustering coefficient served as global statistical network characteristics. Results Independent on the behavioral condition, epileptic brains exhibited a more regular functional network structure. Similarly, the eyes-closed condition was characterized by a more regular functional network structure in both groups. The amount of network reorganization due to behavioral state changes was similar in both groups. Consistent findings could be achieved for networks derived from EEG but hardly from MEG recordings, and network construction rules had a rather strong impact on our findings. Conclusions Despite the locality of the investigated processes epileptic brain networks differ in their global characteristics from non-epileptic brain networks. Further methodological developments are necessary to improve the characterization of disturbed and normal functional networks. Significance An increased regularity and a diminished modulation capability appear characteristic of epileptic brain networks. Y1 - 2010 U6 - https://doi.org/10.1016/j.clinph.2009.10.013 SN - 1388-2457 VL - 121 IS - 2 SP - 172 EP - 185 PB - Elsevier CY - Amsterdam ER -