TY - CHAP A1 - Olderog, M. A1 - Mohr, P. A1 - Beging, Stefan A1 - Tsoumpas, C. A1 - Ziemons, Karl T1 - Simulation study on the role of tissue-scattered events in improving sensitivity for a compact time of flight compton positron emission tomograph T2 - 2020 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) N2 - In positron emission tomography improving time, energy and spatial detector resolutions and using Compton kinematics introduces the possibility to reconstruct a radioactivity distribution image from scatter coincidences, thereby enhancing image quality. The number of single scattered coincidences alone is in the same order of magnitude as true coincidences. In this work, a compact Compton camera module based on monolithic scintillation material is investigated as a detector ring module. The detector interactions are simulated with Monte Carlo package GATE. The scattering angle inside the tissue is derived from the energy of the scattered photon, which results in a set of possible scattering trajectories or broken line of response. The Compton kinematics collimation reduces the number of solutions. Additionally, the time of flight information helps localize the position of the annihilation. One of the questions of this investigation is related to how the energy, spatial and temporal resolutions help confine the possible annihilation volume. A comparison of currently technically feasible detector resolutions (under laboratory conditions) demonstrates the influence on this annihilation volume and shows that energy and coincidence time resolution have a significant impact. An enhancement of the latter from 400 ps to 100 ps leads to a smaller annihilation volume of around 50%, while a change of the energy resolution in the absorber layer from 12% to 4.5% results in a reduction of 60%. The inclusion of single tissue-scattered data has the potential to increase the sensitivity of a scanner by a factor of 2 to 3 times. The concept can be further optimized and extended for multiple scatter coincidences and subsequently validated by a reconstruction algorithm. Y1 - 2021 SN - 978-1-7281-7693-2 U6 - http://dx.doi.org/10.1109/NSS/MIC42677.2020.9507901 N1 - 2020 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 31 Oct.-7 Nov. 2020, Boston, MA, USA PB - IEEE ER - TY - JOUR A1 - Brockhaus, Moritz K. A1 - Behbahani, Mehdi A1 - Muris, Farina A1 - Jansen, Sebastian V. A1 - Schmitz- Rode, Thomas A1 - Steinseifer, Ulrich A1 - Clauser, Johanna C. T1 - In vitro thrombogenicity testing of pulsatile mechanical circulatory support systems: Design and proof-of-concept JF - Artificial Organs N2 - Thrombogenic complications are a main issue in mechanical circulatory support (MCS). There is no validated in vitro method available to quantitatively assess the thrombogenic performance of pulsatile MCS devices under realistic hemodynamic conditions. The aim of this study is to propose a method to evaluate the thrombogenic potential of new designs without the use of complex in-vivo trials. This study presents a novel in vitro method for reproducible thrombogenicity testing of pulsatile MCS systems using low molecular weight heparinized porcine blood. Blood parameters are continuously measured with full blood thromboelastometry (ROTEM; EXTEM, FIBTEM and a custom-made analysis HEPNATEM). Thrombus formation is optically observed after four hours of testing. The results of three experiments are presented each with two parallel loops. The area of thrombus formation inside the MCS device was reproducible. The implantation of a filter inside the loop catches embolizing thrombi without a measurable increase of platelet activation, allowing conclusions of the place of origin of thrombi inside the device. EXTEM and FIBTEM parameters such as clotting velocity (α) and maximum clot firmness (MCF) show a total decrease by around 6% with a characteristic kink after 180 minutes. HEPNATEM α and MCF rise within the first 180 minutes indicate a continuously increasing activation level of coagulation. After 180 minutes, the consumption of clotting factors prevails, resulting in a decrease of α and MCF. With the designed mock loop and the presented protocol we are able to identify thrombogenic hot spots inside a pulsatile pump and characterize their thrombogenic potential. Y1 - 2021 U6 - http://dx.doi.org/10.1111/aor.14046 SN - 1525-1594 VL - 45 IS - 12 SP - 1513 EP - 1521 PB - Wiley CY - Weinheim ER - TY - CHAP A1 - Merkens, Torsten A1 - Hebel, Christoph T1 - Sharing mobility concepts – flexible, sustainable, smart T2 - Proceedings of the 1st UNITED – Southeast Asia Automotive Interest Group (SAIG) KW - Sharing mobility KW - electro mobility KW - business models KW - mobility behaviour Y1 - 2021 SN - 978-3-902103-94-9 N1 - Proceedings of the 1st UNITED – Southeast Asia Automotive Interest Group (SAIG), International Conference, International Collaboration towards Sustainable and Green, Automotive Technology, 21-22 April 2021 Chulalongkorn University, Thailand SP - 43 EP - 44 ER - TY - JOUR A1 - Neumaier, Felix A1 - Weiss, Miriam A1 - Veldeman, Michael A1 - Kotliar, Konstantin A1 - Wiesmann, Martin A1 - Schulze-Steinen, Henna A1 - Höllig, Anke A1 - Clusmann, Hans A1 - Schubert, Gerrit Alexander A1 - Albanna, Walid T1 - Changes in endogenous daytime melatonin levels after aneurysmal subarachnoid hemorrhage – preliminary findings from an observational cohort study JF - Clinical Neurology and Neurosurgery N2 - Aneurysmal subarachnoid hemorrhage (aSAH) is associated with early and delayed brain injury due to several underlying and interrelated processes, which include inflammation, oxidative stress, endothelial, and neuronal apoptosis. Treatment with melatonin, a cytoprotective neurohormone with anti-inflammatory, anti-oxidant and anti-apoptotic effects, has been shown to attenuate early brain injury (EBI) and to prevent delayed cerebral vasospasm in experimental aSAH models. Less is known about the role of endogenous melatonin for aSAH outcome and how its production is altered by the pathophysiological cascades initiated during EBI. In the present observational study, we analyzed changes in melatonin levels during the first three weeks after aSAH. KW - constructive alignment KW - examination KW - long-term retention KW - multimodal KW - practical learning Y1 - 2021 U6 - http://dx.doi.org/10.1016/j.clineuro.2021.106870 SN - 0303-8467 VL - 208 IS - Article No.: 106870 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Hugenroth, Kristin A1 - Borchardt, Ralf A1 - Ritter, Philine A1 - Groß‑Hardt, Sascha A1 - Meyns, Bart A1 - Verbelen, Tom A1 - Steinseifer, Ulrich A1 - Kaufmann, Tim A. S. A1 - Engelmann, Ulrich M. T1 - Optimizing cerebral perfusion and hemodynamics during cardiopulmonary bypass through cannula design combining in silico, in vitro and in vivo input JF - Scientific Reports N2 - Cardiopulmonary bypass (CPB) is a standard technique for cardiac surgery, but comes with the risk of severe neurological complications (e.g. stroke) caused by embolisms and/or reduced cerebral perfusion. We report on an aortic cannula prototype design (optiCAN) with helical outflow and jet-splitting dispersion tip that could reduce the risk of embolic events and restores cerebral perfusion to 97.5% of physiological flow during CPB in vivo, whereas a commercial curved-tip cannula yields 74.6%. In further in vitro comparison, pressure loss and hemolysis parameters of optiCAN remain unaffected. Results are reproducibly confirmed in silico for an exemplary human aortic anatomy via computational fluid dynamics (CFD) simulations. Based on CFD simulations, we firstly show that optiCAN design improves aortic root washout, which reduces the risk of thromboembolism. Secondly, we identify regions of the aortic intima with increased risk of plaque release by correlating areas of enhanced plaque growth and high wall shear stresses (WSS). From this we propose another easy-to-manufacture cannula design (opti2CAN) that decreases areas burdened by high WSS, while preserving physiological cerebral flow and favorable hemodynamics. With this novel cannula design, we propose a cannulation option to reduce neurological complications and the prevalence of stroke in high-risk patients after CPB. Y1 - 2021 U6 - http://dx.doi.org/10.1038/s41598-021-96397-2 SN - 2045-2322 VL - 11 IS - Art. No. 16800 SP - 1 EP - 12 PB - Springer CY - Berlin ER - TY - JOUR A1 - Poghossian, Arshak A1 - Schöning, Michael Josef T1 - Recent progress in silicon-based biologically sensitive field-effect devices JF - Current Opinion in Electrochemistry N2 - Biologically sensitive field-effect devices (BioFEDs) advantageously combine the electronic field-effect functionality with the (bio)chemical receptor’s recognition ability for (bio)chemical sensing. In this review, basic and widely applied device concepts of silicon-based BioFEDs (ion-sensitive field-effect transistor, silicon nanowire transistor, electrolyte-insulator-semiconductor capacitor, light-addressable potentiometric sensor) are presented and recent progress (from 2019 to early 2021) is discussed. One of the main advantages of BioFEDs is the label-free sensing principle enabling to detect a large variety of biomolecules and bioparticles by their intrinsic charge. The review encompasses applications of BioFEDs for the label-free electrical detection of clinically relevant protein biomarkers, deoxyribonucleic acid molecules and viruses, enzyme-substrate reactions as well as recording of the cell acidification rate (as an indicator of cellular metabolism) and the extracellular potential. Y1 - 2021 U6 - http://dx.doi.org/10.1016/j.coelec.2021.100811 SN - 2451-9103 IS - Article number: 100811 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Tran, Duc Hung A1 - Ebeling, Felix T1 - Die risikoadäquate Bestimmung von Eigenkapitalkosten bei konzerninternen Routinefunktionen JF - Der Betrieb N2 - Eigenkapitalkosten sind eine wesentliche Determinante bei der Wertbestimmung von Unternehmen und Unternehmensteilen. Die Eigenkapitalkosten werden regelmäßig mittels des CAPM bestimmt. Für sog. konzerninterne Routinefunktionen mit geringem Risiko stellt diese Bestimmung mittels CAPM ein Problem dar, da börsennotierte Peergroups für eine zuverlässige Bestimmung des Beta-Faktors meist nicht identifizierbar sind. Damit ergeben sich bei Bewertungen von Routineunternehmen Unsicherheiten und Konfliktpotenzial in steuerlichen Betriebsprüfungen. Dieser Beitrag gibt einen Überblick der in der Praxis genutzten Ansätze und stellt eine theoretische Fundierung zur Bestimmung der Eigenkapitalkosten von konzerninternen Routinefunktionen vor. Dabei wird verdeutlicht, dass Eigenkapitalkosten von konzerninternen Routinefunktionen nicht denen des Gesamtkonzerns entsprechen und Praktikeransätze eine grundsätzliche Berechtigung besitzen. Y1 - 2021 SN - 0005-9935 VL - 74 IS - 29 SP - 1553 EP - 1560 ER - TY - THES A1 - Schultheis, Anna Laura T1 - EmanziPardon: Sind die Aussagen von Simone de Beauvoir aus ‚Das andere Geschlecht‘ heute noch relevant? N2 - Simone de Beauvoir veröffentlichte 1949 ihr Werk ‚Das andere Geschlecht‘, in welchem sie die subjektiven und objektiven Einschränkungen, Belastungen und die Abhängigkeiten vom Mann darlegt, denen Frauen schon seit tausenden Jahren ausgesetzt waren und sind. Aber wie ist das heute? Sind diese Aussagen überhaupt noch aktuell bzw. relevant? Innerhalb der Publikation werden Kernthesen aber auch Textausschnitte aus ihrem Werk aufgeführt sowie aktuelle Artikel, die sich mit der derzeitigen Lage befassen. Durch das gestalterische Konzept innerhalb der Publikation, haben die Lesenden die Möglichkeit, sich konkret mit genau den Themen zu befassen, die jeweils dem persönlichen Interesse entsprechen. Die Publikation dient als Erinnerung und als Nachschlagewerk, um immer wieder lesen können, welche Kämpfe hinsichtlich der Gleichstellung der Geschlechter bereits gekämpft wurden und welche noch gekämpft werden müssen. KW - Emanzipation KW - Geschlechterungerechtigkeit KW - Simone de Beauvoir KW - Feminismus KW - Frauenrolle Y1 - 2021 N1 - Für diese Arbeit steht kein Volltext zur Verfügung. PB - FH Aachen CY - Aachen ER - TY - THES A1 - Rittner, Jasper T1 - Wald im Wandel N2 - Die Arbeit „Wald im Wandel“ beschäftigt sich mit dem derzeitigen Zustand des Waldes in Deutschland und seiner kulturhistorischen Bedeutung. Im dazugehörigen Kurzfilm sieht man Aufnahmen der menschlichen Einflussnahme auf den Wald. Diese wurden mit „waldromantischen“ Motiven umgestaltet. Die Kraft „waldromantischer“ Bilder ist so überzeugend, dass hieraus Überlegungen zu einer klimapolitischen Kampagne entstanden sind. Diese sind auf einer Informations-Webpage mit dem Titel „Projekt: Wald im Wandel“ nachzulesen. Die Arbeit schlägt eine Brücke vom kulturhistorischen Symbol „deutscher Wald“ hin zur Gegenwart - und dem Wald in Deutschland als einem potenziellen klimapolitischen Symbol. KW - Wald KW - Borkenkäfer KW - Klimawandel KW - Waldsterben KW - Waldromantik Y1 - 2021 N1 - Für diese Arbeit steht kein Volltext zur Verfügung. PB - FH Aachen CY - Aachen ER - TY - THES A1 - Koc, Özge Fethiye T1 - OFEKO: Lehrmaterial für sehbehinderte Kinder N2 - In einer Mischklasse, bestehend aus sehenden und nicht-sehenden Kindern, welche nicht schriftlich oder spielerisch miteinander kommunizieren können, gehen einige soziale Aspekte und Lernübungen verloren. Partnerarbeiten und das gegenseitige Kontrollieren der Richtigkeit, beispielsweise bei der Anwendung von Satzzeichen, sind Möglichkeiten, welche die Kinder ohne ein gemeinsames Material nicht wahrnehmen können. Diese Arbeit ermöglicht ein gemeinsames Arbeiten aller Kinder durch dasselbe Material. Hierfür dienen dreidimensionale Objekte, welche im STL-Dateiformat zur Verfügung stehen. Es eignet sich für schriftliche und geografische Arbeiten. Des Weiteren ist ein Memory-Spiel enthalten, welches ebenso von sehenden und nicht-sehenden Kinder gespielt werden kann. Diese STLs können weltweit verschickt werden, sodass diese beliebig mit einem 3D-Drucker gedruckt werden können. KW - Empathie KW - Mischklasse KW - STL Dateiformat KW - Partnerarbeiten KW - Empathy Y1 - 2021 N1 - Für diese Arbeit steht kein Volltext zur Verfügung. PB - FH Aachen CY - Aachen ER - TY - THES A1 - Kober, Sophie T1 - DO or DIE: Leistungssport N2 - Es ist dieser eine Moment, der über Versagen oder Erfolg entscheidet. Dieser Augenblick, der so unfassbar wichtig ist und dennoch nicht mal eine Sekunde dauert. Als Leistungssportler bereitet man sich immer und immer wieder auf diesen einen Moment vor. Wie unterscheidet sich dieser Moment in verschiedenen Sportarten? Gibt es ihn überhaupt in jeder Sportart? Das Projekt „Do or Die“ fokussiert sich auf entscheidende und wichtige Situationen in unterschiedlichen Sportarten und zeigt dabei die Facetten und Vielseitigkeit des Leistungssports auf. In einem besonderen Konzept wird der Fokus auf genau diese Momente gelegt und greift den Aspekt des Scheiterns und Erfolgs auf. Es wird untersucht, wie sichtbar diese Augenblicke nach außen hin sind oder inwiefern entscheidende Momente auch nur im Kopf stattfinden und durch Emotionen zu erkennen sind. KW - Sport KW - Leistungssport KW - Emotionen KW - Scheitern KW - Erfolg Y1 - 2021 N1 - Für diese Arbeit steht kein Volltext zur Verfügung. PB - FH Aachen CY - Aachen ER - TY - THES A1 - Khalaimova, Karina T1 - Neuerfindung der Ligaturen N2 - Gegenstand des Projekts ist, Ligaturen als erweiterte Mittel der Informationsübertragung einzusetzen. Ligaturen als zusätzliches Instrument sollen die visuelle Komponente des Textes unterstützen, ihm die gewisse Frische einhauchen und ihn hiermit insgesamt sichtbarer, origineller und moderner machen. Der Einsatzbereich erstreckt sich hierbei in die verschiedensten Bereiche hin über Design und Werbung, als auch im Handel oder in sozialen Bereichen. Hierbei kann eine große Anzahl an Wörtern neue Formen annehmen und mithin an neuem Leben und Bedeutung gewinnen, was sicherlich die allgemeinen Sprachmittel bereichern wird. Auf einer historischen Basis und mit Hilfe der Dekonstruktion wurden neue Formen der Ligaturen geschaffen — seltsame, kontroverse, auffällige und einzigartige. KW - Typografie KW - Ligaturen KW - Schriftmuster KW - Lateinisch KW - Kyrillisch Y1 - 2021 N1 - Für diese Arbeit steht kein Volltext zur Verfügung. PB - FH Aachen CY - Aachen ER - TY - THES A1 - Funger, Marvin T1 - Historie kinetischer Typografie: zeitliche Abbildung der Entstehung und Veränderung kinetischer Typografie N2 - Die heutige, vielfältige kinetische Typografie hat eine lange Entwicklung durchgemacht. Die Darstellung dieser in einer zeitlichen Reihenfolge vermittelt ein Verständnis über Ursprung und Evolution. Die Publikation stellt die historische, analoge sowie die moderne, digitale Entwicklung dar. Dabei wird die Verbindung und der Einfluss der damaligen Gestaltung in der heutigen Umsetzung beleuchtet. Die Plakatreihe erklärt drei Anwendungsmöglichkeiten der kinetischen Typografie. Hierbei werden teils reale Objekte nachgestellt, um die Wiedererkennung dieser im Alltag zu fördern. Gemeinsam zeigen die Plakate und die Publikation ein breites Spektrum der kinetischen Typografie und fördern das Verständnis dieser digitalen Umsetzung von Schrift in bewegter Form. KW - Bewegung KW - Typografie KW - Kinetik KW - Digitalisierung KW - Abbildungen Y1 - 2021 PB - FH Aachen CY - Aachen ER - TY - JOUR A1 - Kasch, Susanne A1 - Schmidt, Thomas A1 - Jahn, Simon A1 - Eichler, Fabian A1 - Thurn, Laura A1 - Bremen, Sebastian T1 - Lösungsansätze und Verfahrenskonzepte zum Laserstrahlschmelzen von Glas JF - Schweissen und Schneiden Y1 - 2021 SN - 0036-7184 VL - 73 IS - Heft 1-2 SP - 32 EP - 39 PB - DVS Verlag CY - Düsseldorf ER - TY - THES A1 - Jung, Alexander T1 - Electromechanical modelling and simulation of hiPSC-derived cardiac cell cultures Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?https://nbn-resolving.org/urn:nbn:de:hbz:464-20210624-134942-7 SN - 978-3-9821811-1-0 N1 - Dissertation, Universität Duisburg-Essen, 2021 PB - Universität Duisburg-Essen ER - TY - CHAP A1 - Tran, Ngoc Trinh A1 - Staat, Manfred T1 - FEM shakedown analysis of Kirchhoff-Love plates under uncertainty of strength T2 - Proceedings of UNCECOMP 2021 N2 - A new formulation to calculate the shakedown limit load of Kirchhoff plates under stochastic conditions of strength is developed. Direct structural reliability design by chance con-strained programming is based on the prescribed failure probabilities, which is an effective approach of stochastic programming if it can be formulated as an equivalent deterministic optimization problem. We restrict uncertainty to strength, the loading is still deterministic. A new formulation is derived in case of random strength with lognormal distribution. Upper bound and lower bound shakedown load factors are calculated simultaneously by a dual algorithm. Y1 - 2021 SN - 978-618-85072-6-5 U6 - http://dx.doi.org/10.7712/120221.8041.19047 N1 - Proceedings of UNCECOMP 2021, 4th International Conference on Uncertainty Quantification in Computational Sciences and Engineering, streamed from Athens, Greece, 28–30 June 2021. SP - 323 EP - 338 ER - TY - CHAP A1 - Hüning, Felix A1 - Stüttgen, Marcel T1 - Work in Progress: Interdisciplinary projects in times of COVID-19 crisis – challenges, risks and chances T2 - 2021 IEEE Global Engineering Education Conference (EDUCON) Y1 - 2021 U6 - http://dx.doi.org/10.1109/EDUCON46332.2021.9454006 SP - 1175 EP - 1179 ER - TY - CHAP A1 - Hoegen, Anne von A1 - Doncker, Rik W. De A1 - Bragard, Michael A1 - Hoegen, Svenja von T1 - Problem-Based Learning in Automation Engineering: Performing a Remote Laboratory Session Serving Various Educational Attainments T2 - 2021 IEEE Global Engineering Education Conference (EDUCON) Y1 - 2021 U6 - http://dx.doi.org/10.1109/EDUCON46332.2021.9453925 SP - 1605 EP - 1614 ER - TY - THES A1 - Holtschlag, Uli T1 - tape foundry: Eine Distribubutionsplattform für studentische Schriften N2 - Die »tape foundry« ist eine interdisziplinäre Distributionsplattform für studentische Schriften, die Studierende auf dem großen Type-Design Markt neu platziert und einen Raum zur Entfaltung gibt. Besonders durch Instagram ist die heutige Type-Designszene größer denn je und viele Entwürfe gehen in der Maße unter. Um diesem Phänomen entgegenzuwirken wurde die »tape foundry« ins Leben gerufen. Sie versucht mit der Kombination aus Fotografie, Type Design und der Funktion als Kassettenlabel neue interdisziplinäre Wege zu gehen, um sich von der klassischen Ästhetik abzusetzen. Die Webseite stellt sich bewusst gegen gängige UX/UI Standards und setzt auf neue Nutzungsprinzipien kombiniert mit einer lauten kontrastreichen Bildwelt. KW - Schriftgestaltung KW - UX/UI Gestaltung KW - Independent type design KW - UX Design KW - UI Design Y1 - 2021 N1 - Für diese Arbeit steht kein Volltext zur Verfügung. PB - FH Aachen CY - Aachen ER - TY - THES A1 - Dreßen, Samira T1 - Teach and Learn-Platform: eine Applikation für Bildungseinrichtungen, Schüler und Studenten N2 - Die Applikation „Slot“ ist eine lehrbegleitende Kommunikations- und Kooperationsplattform, die eine zeitgemäße Lehre, Studienorganisation und Präsentation zulässt. Slot dient dabei nicht nur als Hilfestellung für Lehrende und Lernende, sondern ermöglicht auch die vollständige Durchführung von effizientem Unterricht. Den Lernenden soll maximale Kontrolle zur Erarbeitung ihres Wissens und Übersichtlichkeit in der Kommunikation geboten werden. Um für die unterschiedlichen Nutzergruppen ein benutzerfreundliches System zu schaffen, steht eine breitgefächerte Funktionsauswahl zur Verfügung: Videochat, Messenger, VR-Raum, Whiteboard, Aufgabenübersicht, Datenabgabe, Kalender, Profil und ToDo-List. Die Nutzungsmöglichkeiten können individuell auf die unterschiedlichen Nutzergruppen und deren entsprechenden Bedürfnissen angepasst werden. KW - Online Lehre KW - E-Learning KW - UI/UX Design KW - Digitale Kommunikation KW - Blended Learning Y1 - 2021 N1 - Für diese Arbeit steht kein Volltext zur Verfügung. PB - FH Aachen CY - Aachen ER - TY - JOUR A1 - Ball, Christopher Stephen A1 - Vögele, Stefan A1 - Grajewski, Matthias A1 - Kuckshinrichs, Wilhelm T1 - E-mobility from a multi-actor point of view: Uncertainties and their impacts JF - Technological Forecasting and Social Change Y1 - 2021 SN - 0040-1625 U6 - http://dx.doi.org/10.1016/j.techfore.2021.120925 VL - 170 IS - Art. 120925 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Engelmann, Ulrich M. A1 - Shalaby, Ahmed A1 - Shasha, Carolyn A1 - Krishnan, Kannan M. A1 - Krause, Hans-Joachim T1 - Comparative modeling of frequency mixing measurements of magnetic nanoparticles using micromagnetic simulations and Langevin theory JF - Nanomaterials N2 - Dual frequency magnetic excitation of magnetic nanoparticles (MNP) enables enhanced biosensing applications. This was studied from an experimental and theoretical perspective: nonlinear sum-frequency components of MNP exposed to dual-frequency magnetic excitation were measured as a function of static magnetic offset field. The Langevin model in thermodynamic equilibrium was fitted to the experimental data to derive parameters of the lognormal core size distribution. These parameters were subsequently used as inputs for micromagnetic Monte-Carlo (MC)-simulations. From the hysteresis loops obtained from MC-simulations, sum-frequency components were numerically demodulated and compared with both experiment and Langevin model predictions. From the latter, we derived that approximately 90% of the frequency mixing magnetic response signal is generated by the largest 10% of MNP. We therefore suggest that small particles do not contribute to the frequency mixing signal, which is supported by MC-simulation results. Both theoretical approaches describe the experimental signal shapes well, but with notable differences between experiment and micromagnetic simulations. These deviations could result from Brownian relaxations which are, albeit experimentally inhibited, included in MC-simulation, or (yet unconsidered) cluster-effects of MNP, or inaccurately derived input for MC-simulations, because the largest particles dominate the experimental signal but concurrently do not fulfill the precondition of thermodynamic equilibrium required by Langevin theory. KW - Magnetic nanoparticles KW - Frequency mixing magnetic detection KW - Langevin theory KW - Micromagnetic simulation KW - Nonequilibrium dynamics Y1 - 2021 SN - 2079-4991 U6 - http://dx.doi.org/10.3390/nano11051257 N1 - This article belongs to the Special Issue Applications and Properties of Magnetic Nanoparticles VL - 11 IS - 5 SP - 1 EP - 16 PB - MDPI CY - Basel ER - TY - CHAP A1 - Butenweg, Christoph A1 - Gellert, Christoph A1 - Meyer, Udo T1 - Erdbebenbemessung bei Mauerwerksbauten T2 - Mauerwerk Kalender 2021: Kunststoffverankerungen Digitalisierung im Mauerwerksbau N2 - Der vorliegende Beitrag stellt den seismischen Nachweis von Mauerwerksbauten in Deutschland auf Grundlage der DIN EN 1998‐1/NA vor, wobei auch die wesentlichen Änderungen zu der Norm DIN 4149 vergleichend erläutert werden. Vorgestellt werden die Definition der Erdbebeneinwirkung, das seismische Verhalten von Mauerwerksbauten und die Erläuterung der Rechenverfahren. Darauf aufbauend wird die Anwendung an drei Praxisbeispielen demonstriert. Y1 - 2021 SN - 9783433032930 SN - 9783433610732 U6 - http://dx.doi.org/10.1002/9783433610732.ch12 SP - 329 EP - 355 PB - Ernst & Sohn CY - Berlin ER - TY - JOUR A1 - Bernecker, Andreas A1 - Boyer, Pierre C. A1 - Gathmann, Christina T1 - The Role of Electoral Incentives for Policy Innovation: Evidence from the US Welfare Reform JF - American Economic Journal: Economic Policy Y1 - 2021 U6 - http://dx.doi.org/10.1257/pol.20190690 SN - 1945-774X VL - 13 IS - 2 SP - 26 EP - 57 PB - American Economic Association CY - Nashville, Tenn. ER - TY - JOUR A1 - Valero, Daniel A1 - Schalko, Isabella A1 - Friedrich, Heide A1 - Abad, Jorge D. A1 - Bung, Daniel B. A1 - Donchyts, Gennadii A1 - Felder, Stefan A1 - Ferreira, Rui M. L. A1 - Hohermuth, Benjamin A1 - Kramer, Matthias A1 - Li, Danxun A1 - Mendes, Luis A1 - Moreno-Rodenas, Antonio A1 - Nones, Michael A1 - Paron, Paolo A1 - Ruiz-Villanueva, Virginia A1 - Wang, Ruo-Qian A1 - Franca, Mario J. T1 - Pathways towards democratization of hydro-environment observations and data JF - Iahr White Paper Series Y1 - 2021 IS - 1 SP - 1 EP - 9 PB - International Association for Hydro-Environment Engineering and Research (IAHR) ER - TY - JOUR A1 - Neumaier, Felix A1 - Kotliar, Konstantin A1 - Haeren, Roel Hubert Louis A1 - Temel, Yasin A1 - Lüke, Jan Niklas A1 - Seyam, Osama A1 - Lindauer, Ute A1 - Clusmann, Hans A1 - Hescheler, Jürgen A1 - Schubert, Gerrit Alexander A1 - Schneider, Toni A1 - Albanna, Walid T1 - Retinal Vessel Responses to Flicker Stimulation Are Impaired in Ca v 2.3-Deficient Mice—An in- vivo Evaluation Using Retinal Vessel Analysis (RVA) JF - Frontiers in Neurology Y1 - 2021 U6 - http://dx.doi.org/10.3389/fneur.2021.659890 VL - 12 SP - 1 EP - 11 PB - Frontiers ER - TY - JOUR A1 - Hackl, Michael A1 - Nacov, Julia A1 - Kammerlohr, Sandra A1 - Staat, Manfred A1 - Buess, Eduard A1 - Leschinger, Tim A1 - Müller, Lars P. A1 - Wegmann, Kilian T1 - Intratendinous Strain Variations of the Supraspinatus Tendon Depending on Repair Technique: A Biomechanical Analysis Regarding the Cause of Medial Cuff Failure JF - The American Journal of Sports Medicine Y1 - 2021 U6 - http://dx.doi.org/10.1177/03635465211006138 SN - 1552-3365 SN - 0363-5465 VL - 49 IS - 7 SP - 1847 EP - 1853 PB - Sage CY - London ER - TY - JOUR A1 - Harzheim, Thomas A1 - Mühmel, Marc A1 - Heuermann, Holger T1 - A SFCW harmonic radar system for maritime search and rescue using passive and active tags JF - International Journal of Microwave and Wireless Technologies N2 - This paper introduces a new maritime search and rescue system based on S-band illumination harmonic radar (HR). Passive and active tags have been developed and tested while attached to life jackets and a small boat. In this demonstration test carried out on the Baltic Sea, the system was able to detect and range the active tags up to a distance of 5800 m using an illumination signal transmit-power of 100 W. Special attention is given to the development, performance, and conceptual differences between passive and active tags used in the system. Guidelines for achieving a high HR dynamic range, including a system components description, are given and a comparison with other HR systems is performed. System integration with a commercial maritime X-band navigation radar is shown to demonstrate a solution for rapid search and rescue response and quick localization. KW - Radar KW - microwave measurements KW - harmonic radar KW - harmonic radar tags KW - nonlinear VNA measurements Y1 - 2021 U6 - http://dx.doi.org/10.1017/S1759078721000520 VL - 13 IS - Special Issue 7 SP - 691 EP - 707 PB - Cambridge University Press CY - Cambridge ER - TY - JOUR A1 - Hugenroth, Kristin A1 - Neidlin, Michael A1 - Engelmann, Ulrich M. A1 - Kaufmann, Tim A. S. A1 - Steinseifer, Ulrich A1 - Heilmann, Torsten T1 - Tipless Transseptal Cannula Concept Combines Improved Hemodynamic Properties and Risk‐Reduced Placement: an In Silico Proof‐of‐Concept JF - Artificial Organs Y1 - 2021 U6 - http://dx.doi.org/10.1111/aor.13964 SN - 1525-1594 IS - Accepted Article PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Götten, Falk A1 - Havermann, Marc A1 - Braun, Carsten A1 - Marino, Matthew A1 - Bil, Cees T1 - Aerodynamic Investigations of UAV Sensor Turrets - A Combined Wind-tunnel and CFD Approach JF - SciTech 2021, AIAA SciTech Forum, online, WW, Jan 11-15, 2021 Y1 - 2021 U6 - http://dx.doi.org/10.2514/6.2021-1535 SP - 1 EP - 12 PB - AIAA CY - Reston, Va. ER - TY - CHAP A1 - Ferrein, Alexander A1 - Meeßen, Marcus A1 - Limpert, Nicolas A1 - Schiffer, Stefan ED - Lepuschitz, Wilfried T1 - Compiling ROS Schooling Curricula via Contentual Taxonomies T2 - Robotics in Education Y1 - 2021 SN - 978-3-030-67411-3 U6 - http://dx.doi.org/10.1007/978-3-030-67411-3_5 N1 - RiE: International Conference on Robotics in Education (RiE); Advances in Intelligent Systems and Computing book series (AISC, volume 1316) SP - 49 EP - 60 PB - Springer CY - Cham ER - TY - JOUR A1 - Becht, Alexander A1 - Schollmayer, Curd A1 - Monakhova, Yulia A1 - Holzgrabe, Ulrike T1 - Tracing the origin of paracetamol tablets by near-infrared, mid-infrared, and nuclear magnetic resonance spectroscopy using principal component analysis and linear discriminant analysis JF - Analytical and Bioanalytical Chemistry N2 - Most drugs are no longer produced in their own countries by the pharmaceutical companies, but by contract manufacturers or at manufacturing sites in countries that can produce more cheaply. This not only makes it difficult to trace them back but also leaves room for criminal organizations to fake them unnoticed. For these reasons, it is becoming increasingly difficult to determine the exact origin of drugs. The goal of this work was to investigate how exactly this is possible by using different spectroscopic methods like nuclear magnetic resonance and near- and mid-infrared spectroscopy in combination with multivariate data analysis. As an example, 56 out of 64 different paracetamol preparations, collected from 19 countries around the world, were chosen to investigate whether it is possible to determine the pharmaceutical company, manufacturing site, or country of origin. By means of suitable pre-processing of the spectra and the different information contained in each method, principal component analysis was able to evaluate manufacturing relationships between individual companies and to differentiate between production sites or formulations. Linear discriminant analysis showed different results depending on the spectral method and purpose. For all spectroscopic methods, it was found that the classification of the preparations to their manufacturer achieves better results than the classification to their pharmaceutical company. The best results were obtained with nuclear magnetic resonance and near-infrared data, with 94.6%/99.6% and 98.7/100% of the spectra of the preparations correctly assigned to their pharmaceutical company or manufacturer. KW - IR KW - Manufacturer KW - Linear discriminant analysis KW - Principal component analysis Y1 - 2021 U6 - http://dx.doi.org/10.1007/s00216-021-03249-z SN - 1618-2650 VL - 413 SP - 3107 EP - 3118 PB - Springer Nature ER - TY - JOUR A1 - Bohndick, Carla A1 - Bosse, Elke A1 - Jänsch, Vanessa K. A1 - Barnat, Miriam T1 - How different diversity factors affect the perception of first-year requirements in higher education JF - Frontline Learning Research N2 - In the light of growing university entry rates, higher education institutions not only serve larger numbers of students, but also seek to meet first-year students’ ever more diverse needs. Yet to inform universities how to support the transition to higher education, research only offers limited insights. Current studies tend to either focus on the individual factors that affect student success or they highlight students’ social background and their educational biography in order to examine the achievement of selected, non-traditional groups of students. Both lines of research appear to lack integration and often fail to take organisational diversity into account, such as different types of higher education institutions or degree programmes. For a more comprehensive understanding of student diversity, the present study includes individual, social and organisational factors. To gain insights into their role for the transition to higher education, we examine how the different factors affect the students’ perception of the formal and informal requirements of the first year as more or less difficult to cope with. As the perceived requirements result from both the characteristics of the students and the institutional context, they allow to investigate transition at the interface of the micro and the meso level of higher education. Latent profile analyses revealed that there are no profiles with complex patterns of perception of the first-year requirements, but the identified groups rather differ in the overall level of perceived challenges. Moreover, SEM indicates that the differences in the perception largely depend on the individual factors self-efficacy and volition. Y1 - 2021 U6 - http://dx.doi.org/10.14786/flr.v9i2.667 SN - 2295-3159 VL - 9 IS - 2 SP - 78 EP - 95 PB - EARLI ER - TY - JOUR A1 - Waldvogel, Janice A1 - Ritzmann, Ramona A1 - Freyler, Kathrin A1 - Helm, Michael A1 - Monti, Elena A1 - Albracht, Kirsten A1 - Stäudle, Benjamin A1 - Gollhofer, Albert A1 - Narici, Marco T1 - The Anticipation of Gravity in Human Ballistic Movement JF - Frontiers in Physiology N2 - Stretch-shortening type actions are characterized by lengthening of the pre-activated muscle-tendon unit (MTU) in the eccentric phase immediately followed by muscle shortening. Under 1 g, pre-activity before and muscle activity after ground contact, scale muscle stiffness, which is crucial for the recoil properties of the MTU in the subsequent push-off. This study aimed to examine the neuro-mechanical coupling of the stretch-shortening cycle in response to gravity levels ranging from 0.1 to 2 g. During parabolic flights, 17 subjects performed drop jumps while electromyography (EMG) of the lower limb muscles was combined with ultrasound images of the gastrocnemius medialis, 2D kinematics and kinetics to depict changes in energy management and performance. Neuro-mechanical coupling in 1 g was characterized by high magnitudes of pre-activity and eccentric muscle activity allowing an isometric muscle behavior during ground contact. EMG during pre-activity and the concentric phase systematically increased from 0.1 to 1 g. Below 1 g the EMG in the eccentric phase was diminished, leading to muscle lengthening and reduced MTU stretches. Kinetic energy at take-off and performance were decreased compared to 1 g. Above 1 g, reduced EMG in the eccentric phase was accompanied by large MTU and muscle stretch, increased joint flexion amplitudes, energy loss and reduced performance. The energy outcome function established by linear mixed model reveals that the central nervous system regulates the extensor muscles phase- and load-specifically. In conclusion, neuro-mechanical coupling appears to be optimized in 1 g. Below 1 g, the energy outcome is compromised by reduced muscle stiffness. Above 1 g, loading progressively induces muscle lengthening, thus facilitating energy dissipation. Y1 - 2021 U6 - http://dx.doi.org/10.3389/fphys.2021.614060 SN - 1664-042X PB - Frontiers CY - Lausanne ER - TY - JOUR A1 - Lowis, Carsten A1 - Ferguson, Simon A1 - Paulßen, Elisabeth A1 - Hoehr, Cornelia T1 - Improved Sc-44 production in a siphon-style liquid target on a medical cyclotron JF - Applied Radiation and Isotopes Y1 - 2021 U6 - http://dx.doi.org/10.1016/j.apradiso.2021.109675 SN - 0969-8043 VL - 172 IS - Art. 109675 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Wert, Stefan A1 - Iken, Heiko A1 - Schöning, Michael Josef A1 - Matysik, Frank-Michael T1 - Development of a temperature‐pulse enhanced electrochemical glucose biosensor and characterization of its stability via scanning electrochemical microscopy JF - Electroanalysis N2 - Glucose oxidase (GOx) is an enzyme frequently used in glucose biosensors. As increased temperatures can enhance the performance of electrochemical sensors, we investigated the impact of temperature pulses on GOx that was drop-coated on flattened Pt microwires. The wires were heated by an alternating current. The sensitivity towards glucose and the temperature stability of GOx was investigated by amperometry. An up to 22-fold increase of sensitivity was observed. Spatially resolved enzyme activity changes were investigated via scanning electrochemical microscopy. The application of short (<100 ms) heat pulses was associated with less thermal inactivation of the immobilized GOx than long-term heating. Y1 - 2021 U6 - http://dx.doi.org/10.1002/elan.202100089 SN - 1521-4109 IS - Early View PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Maurischat, Andreas T1 - Algebraic independence of the Carlitz period and its hyperderivatives KW - Drinfeld modules KW - t-modules KW - Transcendence KW - Hyperdifferentials Y1 - 2021 N1 - Zweitveröffentlichung. Verlagsveröffentlichung: https://doi.org/10.1016/j.jnt.2022.01.006 SP - 1 EP - 12 ER - TY - CHAP A1 - El Moussaoui, Noureddine A1 - Kassmi, Khalil A1 - Alexopoulos, Spiros A1 - Schwarzer, Klemens A1 - Chayeb, Hamid A1 - Bachiri, Najib T1 - Simulation studies on a new innovative design of a hybrid solar distiller MSDH alimented with a thermal and photovoltaic energy T2 - Materialstoday: Proceedings Y1 - 2021 U6 - http://dx.doi.org/10.1016/j.matpr.2021.03.115 SN - 2214-7853 ER - TY - JOUR A1 - Molinnus, Denise A1 - Drinic, Aleksander A1 - Iken, Heiko A1 - Kröger, Nadja A1 - Zinser, Max A1 - Smeets, Ralf A1 - Köpf, Marius A1 - Kopp, Alexander A1 - Schöning, Michael Josef T1 - Towards a flexible electrochemical biosensor fabricated from biocompatible Bombyx mori silk JF - Biosensors and Bioelectronics Y1 - 2021 U6 - http://dx.doi.org/10.1016/j.bios.2021.113204 SN - 0956-5663 VL - 183 IS - Art. 113204 PB - Elsevier CY - Amsterdam ER - TY - THES A1 - Bayer, Robin T1 - Development of a novel in-vitro vascular model for determination of physiological and pathophysiological mechanobiology Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:38-362212 N1 - Dissertation, Universität zu Köln, 2021 PB - Universität zu Köln CY - Köln ER - TY - BOOK A1 - Laack, Walter van T1 - Größer als das ganze Universum Y1 - 2021 SN - 978-3-936624-38-0 PB - van Laack GmbH CY - Aachen ER - TY - JOUR A1 - Yoshinobu, Tatsuo A1 - Schöning, Michael Josef T1 - Light-addressable potentiometric sensors (LAPS) for cell monitoring and biosensing JF - Current Opinion in Electrochemistry Y1 - 2021 U6 - http://dx.doi.org/10.1016/j.coelec.2021.100727 SN - 2451-9103 IS - In Press, Journal Pre-proof PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Hennes, Philipp A1 - Laumann, Jörg T1 - Ansatz der Drehbehinderung aus Koppelpfetten mit dünnwandigen kaltgeformten Z-Profilen JF - Stahlbau Y1 - 2021 U6 - http://dx.doi.org/10.1002/stab.202000104 SN - 1437-1049 VL - 90 IS - 3 SP - 158 EP - 168 PB - Ernst & Sohn CY - Berlin ER - TY - JOUR A1 - Bergs, Michel A1 - Monakhova, Yulia A1 - Diehl, Bernd W. A1 - Konow, Christopher A1 - Völkering, Georg A1 - Pude, Ralf A1 - Schulze, Margit T1 - Lignins isolated via catalyst-free organosolv pulping from Miscanthus x giganteus, M. sinensis, M. robustus and M. nagara: a comparative study JF - Molecules N2 - As a low-input crop, Miscanthus offers numerous advantages that, in addition to agricultural applications, permits its exploitation for energy, fuel, and material production. Depending on the Miscanthus genotype, season, and harvest time as well as plant component (leaf versus stem), correlations between structure and properties of the corresponding isolated lignins differ. Here, a comparative study is presented between lignins isolated from M. x giganteus, M. sinensis, M. robustus and M. nagara using a catalyst-free organosolv pulping process. The lignins from different plant constituents are also compared regarding their similarities and differences regarding monolignol ratio and important linkages. Results showed that the plant genotype has the weakest influence on monolignol content and interunit linkages. In contrast, structural differences are more significant among lignins of different harvest time and/or season. Analyses were performed using fast and simple methods such as nuclear magnetic resonance (NMR) spectroscopy. Data was assigned to four different linkages (A: β-O-4 linkage, B: phenylcoumaran, C: resinol, D: β-unsaturated ester). In conclusion, A content is particularly high in leaf-derived lignins at just under 70% and significantly lower in stem and mixture lignins at around 60% and almost 65%. The second most common linkage pattern is D in all isolated lignins, the proportion of which is also strongly dependent on the crop portion. Both stem and mixture lignins, have a relatively high share of approximately 20% or more (maximum is M. sinensis Sin2 with over 30%). In the leaf-derived lignins, the proportions are significantly lower on average. Stem samples should be chosen if the highest possible lignin content is desired, specifically from the M. x giganteus genotype, which revealed lignin contents up to 27%. Due to the better frost resistance and higher stem stability, M. nagara offers some advantages compared to M. x giganteus. Miscanthus crops are shown to be very attractive lignocellulose feedstock (LCF) for second generation biorefineries and lignin generation in Europe. Y1 - 2021 U6 - http://dx.doi.org/10.3390/molecules26040842 SN - 1420-3049 N1 - Special Issue Lignin – A Natural Resource with Huge Potential https://www.mdpi.com/journal/molecules/special_issues/lignin_natural VL - 26 IS - 4 PB - MDPI CY - Basel ER - TY - JOUR A1 - Fissabre, Anke T1 - Ein pazifistisches Kriegerdenkmal der Moderne. Das Totenkreuz von Rudolf Schwarz JF - In situ: Zeitschrift für Architekturgeschichte Y1 - 2021 SN - 1866-959X N1 - gedruckt in der Bereichsbibliothek Bayernallee unter der Signatur 13 Z 959 vorhanden IS - 1 SP - 127 EP - 138 PB - Wernersche Verlagsgesellschaft CY - Worms ER - TY - CHAP A1 - Schulte, Maximilian A1 - Eggert, Mathias T1 - Predicting hourly bitcoin prices based on long short-term memory neural networks T2 - Proceedings of the International Conference on Wirtschaftsinformatik (WI) 2021 N2 - Bitcoin is a cryptocurrency and is considered a high-risk asset class whose price changes are difficult to predict. Current research focusses on daily price movements with a limited number of predictors. The paper at hand aims at identifying measurable indicators for Bitcoin price movement s and the development of a suitable forecasting model for hourly changes. The paper provides three research contributions. First, a set of significant indicators for predicting the Bitcoin price is identified. Second, the results of a trained Long Short-term Memory (LSTM) neural network that predicts price changes on an hourly basis is presented and compared with other algorithms. Third, the results foster discussions of the applicability of neural nets for stock price predictions. In total, 47 input features for a period of over 10 months could be retrieved to train a neural net that predicts the Bitcoin price movements with an error rate of 3.52 %. Y1 - 2021 N1 - 16th International Conference on Wirtschaftsinformatik, March 2021, Essen, Germany ER - TY - CHAP A1 - Funke, Harald A1 - Beckmann, Nils A1 - Keinz, Jan A1 - Horikawa, Atsushi T1 - 30 years of dry low NOx micromix combustor research for hydrogen-rich fuels: an overview of past and present activities T2 - Proceedings of the ASME Turbo Expo 2020: Turbomachinery Technical Conference and Exposition, September 21–25, 2020, Virtual, Online. Vol.: 4B: Combustion, Fuels, and Emissions KW - Micromix KW - Hydrogen KW - Fuel-flexibility KW - NOx KW - Emissions Y1 - 2021 SN - 978-0-7918-8413-3 U6 - http://dx.doi.org/10.1115/GT2020-16328 N1 - Paper No. GT2020-16328, V04BT04A069 PB - American Society of Mechanical Engineers (ASME) ER - TY - CHAP A1 - Heuermann, Holger A1 - Harzheim, Thomas A1 - Mühmel, Marc T1 - A maritime harmonic radar search and rescue system using passive and active tags T2 - 2020 17th European Radar Conference (EuRAD) KW - Harmonic Radar KW - Rescue System KW - Frequency Doubler KW - Transponder KW - Tag Y1 - 2021 SN - 978-2-87487-061-3 U6 - http://dx.doi.org/10.1109/EuRAD48048.2021.00030 N1 - Proceedings of the 17th European Radar Conference, 13th - 15th January 2021, Utrecht, Netherlands SP - 73 EP - 76 PB - IEEE ER - TY - JOUR A1 - Givanoudi, Stella A1 - Cornelis, Peter A1 - Rasschaert, Geertrui A1 - Wackers, Gideon A1 - Iken, Heiko A1 - Rolka, David A1 - Yongabi, Derick A1 - Robbens, Johan A1 - Schöning, Michael Josef A1 - Heyndrickx, Marc A1 - Wagner, Patrick T1 - Selective Campylobacter detection and quantification in poultry: A sensor tool for detecting the cause of a common zoonosis at its source JF - Sensors and Actuators B: Chemical Y1 - 2021 U6 - http://dx.doi.org/10.1016/j.snb.2021.129484 SN - 0925-4005 IS - In Press, Journal Pre-proof SP - Article 129484 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Jablonski, Melanie A1 - Poghossian, Arshak A1 - Severin, Robin A1 - Keusgen, Michael A1 - Wege, Christian A1 - Schöning, Michael Josef T1 - Capacitive Field-Effect Biosensor Studying Adsorption of Tobacco Mosaic Virus Particles JF - Micromachines N2 - Plant virus-like particles, and in particular, tobacco mosaic virus (TMV) particles, are increasingly being used in nano- and biotechnology as well as for biochemical sensing purposes as nanoscaffolds for the high-density immobilization of receptor molecules. The sensitive parameters of TMV-assisted biosensors depend, among others, on the density of adsorbed TMV particles on the sensor surface, which is affected by both the adsorption conditions and surface properties of the sensor. In this work, Ta₂O₅-gate field-effect capacitive sensors have been applied for the label-free electrical detection of TMV adsorption. The impact of the TMV concentration on both the sensor signal and the density of TMV particles adsorbed onto the Ta₂O₅-gate surface has been studied systematically by means of field-effect and scanning electron microscopy methods. In addition, the surface density of TMV particles loaded under different incubation times has been investigated. Finally, the field-effect sensor also demonstrates the label-free detection of penicillinase immobilization as model bioreceptor on TMV particles. KW - capacitive field-effect sensor KW - plant virus detection KW - tobacco mosaic virus (TMV) KW - TMV adsorption KW - Ta₂O₅ gate Y1 - 2021 U6 - http://dx.doi.org/10.3390/mi12010057 VL - 12 IS - 1 PB - MDPI CY - Basel ER - TY - JOUR A1 - Erpicum, Sebastien A1 - Crookston, Brian M. A1 - Bombardelli, Fabian A1 - Bung, Daniel B. A1 - Felder, Stefan A1 - Mulligan, Sean A1 - Oertel, Mario A1 - Palermo, Michele T1 - Hydraulic structures engineering: An evolving science in a changing world JF - Wires Water Y1 - 2021 U6 - http://dx.doi.org/10.1002/wat2.1505 SN - 2049-1948 VL - 8 IS - 2 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Fagan, Andrew J. A1 - Bitz, Andreas A1 - Björkman-Burtscher, Isabella M. A1 - Collins, Christopher M. A1 - Kimbrell, Vera A1 - Raaijmakers, Alexander J. E. T1 - 7T MR Safety JF - Journal of Magnetic Resonance Imaging (JMRI) Y1 - 2021 U6 - http://dx.doi.org/10.1002/jmri.27319 SN - 1522-2586 VL - 53 IS - 2 SP - 333 EP - 346 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Serror, Martin A1 - Hack, Sacha A1 - Henze, Martin A1 - Schuba, Marko A1 - Wehrle, Klaus T1 - Challenges and Opportunities in Securing the Industrial Internet of Things JF - IEEE Transactions on Industrial Informatics Y1 - 2021 U6 - http://dx.doi.org/10.1109/TII.2020.3023507 SN - 1941-0050 VL - 17 IS - 5 SP - 2985 EP - 2996 PB - IEEE CY - New York ER - TY - JOUR A1 - Meyer, Max-Arno A1 - Granrath, Christian A1 - Feyerl, Günter A1 - Richenhagen, Johannes A1 - Kaths, Jakob A1 - Andert, Jakob T1 - Closed-loop platoon simulation with cooperative intelligent transportation systems based on vehicle-to-X communication JF - Simulation Modelling Practice and Theory Y1 - 2021 U6 - http://dx.doi.org/10.1016/j.simpat.2020.102173 SN - 1569-190X VL - 106 IS - Art. 102173 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Seefeldt, Patric A1 - Dachwald, Bernd T1 - Temperature increase on folded solar sail membranes JF - Advances in Space Research Y1 - 2021 U6 - http://dx.doi.org/10.1016/j.asr.2020.09.026 SN - 0273-1177 VL - 67 IS - 9 SP - 2688 EP - 2695 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Tran, Ngoc Trinh A1 - Staat, Manfred T1 - Direct plastic structural design under random strength and random load by chance constrained programming JF - European Journal of Mechanics - A/Solids Y1 - 2021 U6 - http://dx.doi.org/10.1016/j.euromechsol.2020.104106 SN - 0997-7538 VL - 85 IS - Article 104106 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Akimbekov, Nuraly A1 - Digel, Ilya A1 - Abdieva, Gulzhamal A1 - Ualieva, Perizat A1 - Tastambek, Kuanysh T1 - Lignite biosolubilization and bioconversion by Bacillus sp.: the collation of analytical data JF - Biofuels N2 - The vast metabolic potential of microbes in brown coal (lignite) processing and utilization can greatly contribute to innovative approaches to sustainable production of high-value products from coal. In this study, the multi-faceted and complex coal biosolubilization process by Bacillus sp. RKB 7 isolate from the Kazakhstan coal-mining soil is reported, and the derived products are characterized. Lignite solubilization tests performed for surface and suspension cultures testify to the formation of numerous soluble lignite-derived substances. Almost 24% of crude lignite (5% w/v) was solubilized within 14 days under slightly alkaline conditions (pH 8.2). FTIR analysis revealed various functional groups in the obtained biosolubilization products. Analyses of the lignite-derived humic products by UV-Vis and fluorescence spectrometry as well as elemental analysis yielded compatible results indicating the emerging products had a lower molecular weight and degree of aromaticity. Furthermore, XRD and SEM analyses were used to evaluate the biosolubilization processes from mineralogical and microscopic points of view. The findings not only contribute to a deeper understanding of microbe–mineral interactions in coal environments, but also contribute to knowledge of coal biosolubilization and bioconversion with regard to sustainable production of humic substances. The detailed and comprehensive analyses demonstrate the huge biotechnological potential of Bacillus sp. for agricultural productivity and environmental health. KW - humic acid KW - Bacillus sp KW - lignite KW - Biosolubilization Y1 - 2021 SN - 1759-7277 VL - 12 IS - 3 SP - 247 EP - 258 PB - Taylor & Francis CY - London ER - TY - JOUR A1 - Köhler, Klemens A1 - Röpke, René A1 - Wolf, Martin T1 - Through a mirror darkly – On the obscurity of teaching goals in game-based learning in IT security JF - ISAGA 2019: Simulation Gaming Through Times and Disciplines N2 - Teachers and instructors use very specific language communicating teaching goals. The most widely used frameworks of common reference are the Bloom’s Taxonomy and the Revised Bloom’s Taxonomy. The latter provides distinction of 209 different teaching goals which are connected to methods. In Competence Developing Games (CDGs - serious games to convey knowledge) and in IT security education, a two- or three level typology exists, reducing possible learning outcomes to awareness, training, and education. This study explores whether this much simpler framework succeeds in achieving the same range of learning outcomes. Method wise a keyword analysis was conducted. The results were threefold: 1. The words used to describe teaching goals in CDGs on IT security education do not reflect the whole range of learning outcomes. 2. The word choice is nevertheless different from common language, indicating an intentional use of language. 3. IT security CDGs use different sets of terms to describe learning outcomes, depending on whether they are awareness, training, or education games. The interpretation of the findings is that the reduction to just three types of CDGs reduces the capacity to communicate and think about learning outcomes and consequently reduces the outcomes that are intentionally achieved. KW - IT security education KW - Competence Developing Games KW - Game-based learning KW - Keyword analysis KW - Bloom’s Taxonomy Y1 - 2021 U6 - http://dx.doi.org/10.1007/978-3-030-72132-9_6 N1 - ISAGA 2019 - International Simulation and Gaming Association Conference. 26-30 August 2019. Warsaw, Poland. Part of the Lecture Notes in Computer Science book series (LNCS, volume 11988) SP - 61 EP - 73 PB - Springer CY - Cham ER -