TY  - JOUR
A1  - Poghossian, Arshak
A1  - Berndsen, L.
A1  - Schultze, J. W.
A1  - Lüth, H.
A1  - Schöning, Michael Josef
T1  - „High order“ hybrid sensor module based on an identical transducer principle
JF  - Chemical and biological sensors and analytical methods : proceedings of the international symposium / Sensor, Physical Electrochemistry, and Organic and Biological Electrochemistry Divisions. Ed.: M. Butler
Y1  - 2001
SN  - 1-56677-351-2
N1  - International Symposium: Chemical and Biological Sensors and Analytical Methods ; (2 : 2001.)
SP  - 143
EP  - 152
PB  - Electrochemical Society
CY  - Pennington, NJ
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Berndsen, L.
A1  - Schöning, Michael Josef
T1  - Chemical sensor as a physical sensor: ISFET-based flowvelocity, flow-direction and diffusion-coefficient sensor
JF  - Book of abstracts / ed. by J. Saneistr.
Y1  - 2002
SN  - 80-01-02576-4
N1  - Eurosensors ; (16, 2002, Praha)
SP  - 649
EP  - 652
PB  - Czech Technical University, Faculty of Electrical Engineering, Department of Measurement
CY  - Prague
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Berndsen, Lars
A1  - Lüth, Hans
A1  - Schöning, Michael Josef
T1  - Novel concepts for flow-rate and flow-direction determination by means of pH-sensitive ISFETs
JF  - Proceedings of SPIE. 4560 (2001)
Y1  - 2001
SP  - 19
EP  - 27
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Berndsen, Lars
A1  - Schöning, Michael Josef
T1  - Chemical sensor as physical sensor: ISFET-based flowvelocity, flow-direction and diffusion-coefficient sensor
JF  - Sensors and Actuators B. 95 (2003), H. 1-3
Y1  - 2003
SN  - 0925-4005
SP  - 384
EP  - 390
ER  - 
TY  - CHAP
A1  - Poghossian, Arshak
A1  - Bronder, Thomas
A1  - Scheja, S.
A1  - Wu, Chunsheng
A1  - Metzger-Boddien, C.
A1  - Keusgen, M.
A1  - Schöning, Michael Josef
T1  - Label-free Electrostatic Detection of DNA Amplification by PCR Using Capacitive Field-effect Devices
T2  - Procedia Engineering
N2  - A capacitive field-effect EIS (electrolyte-insulator-semiconductor) sensor modified with a positively charged weak polyelectrolyte of poly(allylamine hydrochloride) (PAH)/single-stranded probe DNA (ssDNA) bilayer has been used for a label-free electrostatic detection of pathogen-specific DNA amplification via polymerase chain reaction (PCR). The sensor is able to distinguish between positive and negative PCR solutions, to detect the existence of target DNA amplicons in PCR samples and thus, can be used as tool for a quick verification of DNA amplification and the successful PCR process.
Y1  - 2016
U6  - http://dx.doi.org/10.1016/j.proeng.2016.11.512
SN  - 1877-7058
N1  - Proceedings of the 30th anniversary Eurosensors Conference – Eurosensors 2016, 4-7. Sepember 2016, Budapest, Hungary
VL  - Vol. 168
SP  - 514
EP  - 517
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - CHAP
A1  - Poghossian, Arshak
A1  - Bronder, Thomas
A1  - Wu, Chunsheng
A1  - Schöning, Michael Josef
T1  - Label-free sensing of biomolecules by their intrinsic molecular charge using field-effect devices
T2  - Semiconductor Micro- and Nanoelectonics : Proceedings of the tenth international conference, Yerevan, Armenia, September 11-13
Y1  - 2015
SN  - 978-5-8084-1991-9
SP  - 61
EP  - 63
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Bäcker, Matthias
A1  - Mayer, Dirk
A1  - Schöning, Michael Josef
T1  - Gating capacitive field-effect sensors by the charge of nanoparticle/molecule hybrids
JF  - Nanoscale
Y1  - 2015
U6  - http://dx.doi.org/10.1039/C4NR05987E
SN  - 2040-3372 (E-Journal); 2040-3364 (Print)
SP  - 1023
EP  - 1031
PB  - Royal Society of Chemistry (RSC)
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Cherstvy, A.
A1  - Ingebrandt, S.
A1  - Offenhäusser, A.
A1  - Schöning, Michael Josef
T1  - Possibilities and limitations of label-free detection of DNA hybridization with field-effect-based devices
JF  - Sensors and Actuators B. 111-112 (2005)
Y1  - 2005
SN  - 0925-4005
N1  - Eurosensors XVIII 2004 — The 18th European Conference on Solid-State Transducers
SP  - 470
EP  - 480
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Cherstvy, A.
A1  - Schöning, Michael Josef
T1  - Possibilities and limitations of label-free detection of DNA hybridization with field-effect based devices
JF  - Digest of technical papers : September 12 - 15, 2004, Rome, Italy, Pontificia Universitas Sancto Thoma Aquinate in Urbe / [conference chairperson: C. Di Natale].
Y1  - 2004
SN  - 88-7621-282-5
N1  - Eurosensors ; (18, 2004, Roma)
SP  - 173
EP  - 176
CY  - Roma
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Geissler, Hanno
A1  - Schöning, Michael Josef
T1  - Rapid methods and sensors for milk quality monitoring and spoilage detection
JF  - Biosensors and Bioelectronics
Y1  - 2019
U6  - http://dx.doi.org/10.1016/j.bios.2019.04.040
SN  - 0956-5663
VL  - 140
IS  - Article 111272
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Ingebrandt, S.
A1  - Abouzar, Maryam H.
A1  - Schöning, Michael Josef
T1  - Label-free detection of charged macromolecules by using a field-effect-based sensor platform: Experiments and possible mechanisms of signal generation
JF  - Applied Physics A: Materials Science & Processing. 87 (2007), H. 3
Y1  - 2007
SN  - 0947-8396
N1  - Special Issue “From Surface Science to Nanoscale Devices”
SP  - 517
EP  - 524
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Ingebrandt, S.
A1  - Offenhäusser, A.
A1  - Schöning, Michael Josef
T1  - Field-effect devices for detecting cellular signals
JF  - Seminars in Cell & Developmental Biology. 20 (2009), H. 1
Y1  - 2009
SN  - 1096-3634
SP  - 41
EP  - 48
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - CHAP
A1  - Poghossian, Arshak
A1  - Ingebrandt, S.
A1  - Platen, J.
A1  - Schöning, Michael Josef
T1  - Field-effect sensors with charged macromolecules – from micro towards nano aspects
T2  - Biochemical Sensing Utilisation of Micro-and                       Nanotechnologies, Warschau, Nov. 2005 : Lecture Notes of the                       ICB Seminar / ed.: M. Mascini, W. Torbicz
Y1  - 2006
SP  - 74
EP  - 81
PB  - Polish Academy Sciences Press
CY  - Warsaw
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Ingebrandt, S.
A1  - Yeung, C.-K.
A1  - Offenhäusser, A.
A1  - Schöning, Michael Josef
T1  - Microsensors based on ion-sensitive field-effect transistors for biomedical applications
JF  - Biomedizinische Technik. 49 (2004), H. 2
Y1  - 2004
SN  - 0932-4666
SP  - 1036
EP  - 1037
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Jablonski, Melanie
A1  - Koch, Claudia
A1  - Bronder, Thomas
A1  - Rolka, David
A1  - Wege, Christina
A1  - Schöning, Michael Josef
T1  - Field-effect biosensor using virus particles as scaffolds for enzyme immobilization
JF  - Biosensors and Bioelectronics
N2  - A field-effect biosensor employing tobacco mosaic virus (TMV) particles as scaffolds for enzyme immobilization is presented. Nanotubular TMV scaffolds allow a dense immobilization of precisely positioned enzymes with retained activity. To demonstrate feasibility of this new strategy, a penicillin sensor has been developed by coupling a penicillinase with virus particles as a model system. The developed field-effect penicillin biosensor consists of an Al-p-Si-SiO₂-Ta₂O₅-TMV structure and has been electrochemically characterized in buffer solutions containing different concentrations of penicillin G. In addition, the morphology of the biosensor surface with virus particles was characterized by scanning electron microscopy and atomic force microscopy methods. The sensors possessed a high penicillin sensitivity of ~ 92 mV/dec in a nearly-linear range from 0.1 mM to 10 mM, and a low detection limit of about 50 µM. The long-term stability of the penicillin biosensor was periodically tested over a time period of about one year without any significant loss of sensitivity. The biosensor has also been successfully applied for penicillin detection in bovine milk samples.
Y1  - 2018
U6  - http://dx.doi.org/10.1016/j.bios.2018.03.036
SN  - 0956-5663
VL  - 110
SP  - 168
EP  - 174
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Jablonski, Melanie
A1  - Molinnus, Denise
A1  - Wege, Christina
A1  - Schöning, Michael Josef
T1  - Field-Effect Sensors for Virus Detection: From Ebola to SARS-CoV-2 and Plant Viral Enhancers
JF  - Frontiers in Plant Science
N2  - Coronavirus disease 2019 (COVID-19) is a novel human infectious disease provoked by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Currently, no specific vaccines or drugs against COVID-19 are available. Therefore, early diagnosis and treatment are essential in order to slow the virus spread and to contain the disease outbreak. Hence, new diagnostic tests and devices for virus detection in clinical samples that are faster, more accurate and reliable, easier and cost-efficient than existing ones are needed. Due to the small sizes, fast response time, label-free operation without the need for expensive and time-consuming labeling steps, the possibility of real-time and multiplexed measurements, robustness and portability (point-of-care and on-site testing), biosensors based on semiconductor field-effect devices (FEDs) are one of the most attractive platforms for an electrical detection of charged biomolecules and bioparticles by their intrinsic charge. In this review, recent advances and key developments in the field of label-free detection of viruses (including plant viruses) with various types of FEDs are presented. In recent years, however, certain plant viruses have also attracted additional interest for biosensor layouts: Their repetitive protein subunits arranged at nanometric spacing can be employed for coupling functional molecules. If used as adapters on sensor chip surfaces, they allow an efficient immobilization of analyte-specific recognition and detector elements such as antibodies and enzymes at highest surface densities. The display on plant viral bionanoparticles may also lead to long-time stabilization of sensor molecules upon repeated uses and has the potential to increase sensor performance substantially, compared to conventional layouts. This has been demonstrated in different proof-of-concept biosensor devices. Therefore, richly available plant viral particles, non-pathogenic for animals or humans, might gain novel importance if applied in receptor layers of FEDs. These perspectives are explained and discussed with regard to future detection strategies for COVID-19 and related viral diseases.
Y1  - 2020
U6  - http://dx.doi.org/10.3389/fpls.2020.598103
VL  - 11
IS  - Article 598103
SP  - 1
EP  - 14
PB  - Frontiers
CY  - Lausanne
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Katz, Evgeny
A1  - Schöning, Michael Josef
T1  - Enzyme logic AND-Reset and OR-Reset gates based on a field-effect electronic transducer modified with multi-enzyme membrane
JF  - Chemical Communications
N2  - Capacitive field-effect sensors modified with a multi-enzyme membrane have been applied for an electronic transduction of biochemical signals processed by enzyme-based AND-Reset and OR-Reset logic gates. The local pH change at the sensor surface induced by the enzymatic reaction was used for the activation of the Reset function for the first time.
Y1  - 2015
U6  - http://dx.doi.org/10.1039/C5CC01362C
VL  - 51
SP  - 6564
EP  - 6567
PB  - Royal Society of Chemistry (RSC)
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Krämer, Melina
A1  - Abouzar, Maryam H.
A1  - Pita, Marcos
A1  - Katz, Evgeny
A1  - Schöning, Michael Josef
T1  - Interfacing of biocomputing systems with silicon chips: Enzyme logic gates based on field-effect devices
JF  - Procedia Chemistry. 1 (2009), H. 1
Y1  - 2009
SN  - 1876-6196
N1  - Proceedings of the Eurosensors XXIII conference ; Eurosensors 23
SP  - 682
EP  - 685
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Lüth, H.
A1  - Schultze, J. W.
A1  - Schöning, Michael Josef
T1  - (Bio-)chemical and physical microsensor array using an identical transducer principle
JF  - Scaling down in electrochemistry : electrochemical micro- and nanosystem technology ; proceedings of the 3rd International Symposium on Electrochemical Microsystem Technologies, Garmisch-Patenkirchen, Germany, 11 - 15 September 2000 / ed. by J. W. Schultz
Y1  - 2001
SN  - 0-08-044014-2
SP  - 243
EP  - 249
PB  - Elsevier [u.a.]
CY  - Amsterdam [u.a.]
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Mai, D.-T.
A1  - Mourzina, Y.
A1  - Schöning, Michael Josef
T1  - Impedance effect of an ion-sensitive membrane: characterisation of an EMIS sensor by impedance spectroscopy, capacitance-voltage and constant-capacitance method
JF  - Sensors and Actuators B. 103 (2004), H. 1-2
Y1  - 2004
SN  - 0925-4005
SP  - 423
EP  - 428
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Malzahn, K.
A1  - Abouzar, Maryam H.
A1  - Mehndiratta, P.
A1  - Katz, E.
A1  - Schöning, Michael Josef
T1  - Integration of biomolecular logic gates with field-effect transducers
JF  - Electrochimica Acta. 56 (2011), H. 26
Y1  - 2011
SN  - 0013-4686
SP  - 9661
EP  - 9665
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Platen, J.
A1  - Schöning, Michael Josef
T1  - Towards self-aligned nanostructures by means of layerexpansion technique
JF  - Electrochimica Acta. 51 (2005), H. 5
Y1  - 2005
SN  - 0013-4686
SP  - 838
EP  - 843
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Schultze, J. W.
A1  - Schöning, Michael Josef
T1  - Application of a (bio-)chemical sensor (ISFET) for the detection of physical parameters in liquids
JF  - Electrochimica Acta. 48 (2003), H. 20-22
Y1  - 2003
SP  - 3289
EP  - 3297
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Schultze, J. W.
A1  - Schöning, Michael Josef
T1  - Multi-parameter detection of (bio-)chemical and physical quantities using an identical transducer principle
JF  - Sensors and Actuators B. 91 (2003), H. 1-3
Y1  - 2003
SN  - 0925-4005
SP  - 83
EP  - 91
ER  - 
TY  - CHAP
A1  - Poghossian, Arshak
A1  - Schumacher, Kerstin
A1  - Kloock, Joachim P.
A1  - Rosenkranz, Christian
A1  - Schultze, Joachim W.
A1  - Müller-Veggian, Mattea
A1  - Schöning, Michael Josef
T1  - Functional testing and characterisation of ISFETs on wafer level by means of a micro-droplet cell
N2  - A wafer-level functionality testing and characterisation system for ISFETs (ionsensitive field-effect transistor) is realised by means of integration of a specifically designed capillary electrochemical micro-droplet cell into a commercial wafer prober-station. The developed system allows the identification and selection of “good” ISFETs at the earliest stage and to avoid expensive bonding, encapsulation and packaging processes for nonfunctioning ISFETs and thus, to decrease costs, which are wasted for bad dies. The developed system is also feasible for wafer-level characterisation of ISFETs in terms of sensitivity, hysteresis and response time. Additionally, the system might be also utilised for wafer-level testing of further electrochemical sensors.
KW  - Biosensor
KW  - Biosensorik
KW  - ISFET
KW  - Wafer
KW  - ISFET
KW  - wafer-level testing
KW  - capillary micro-droplet cell
Y1  - 2006
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:a96-opus-1259
ER  - 
TY  - CHAP
A1  - Poghossian, Arshak
A1  - Schusser, Sebastian
A1  - Bäcker, M.
A1  - Leinhos, Marcel
A1  - Schöning, Michael Josef
T1  - Real-time in-situ electrical monitoring of the degradation of biopolymers using semiconductor field-effect devices
T2  - Biodegradable biopolymers. Vol. 1
Y1  - 2015
SN  - 978-1-63483-632-6
SP  - 135
EP  - 153
PB  - Nova Science Publ.
CY  - Hauppauge
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
T1  - Detecting Both Physical and (Bio-)Chemical Parameters by Means of ISFET Devices
JF  - Electroanalysis. 16 (2004), H. 22
Y1  - 2004
SN  - 1040-0397
SP  - 1863
EP  - 1872
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
T1  - "High-order” hybrid FET module for (bio)chemical and physical sensing
JF  - Integrated analytical systems / ed. by Salvador Alegret
Y1  - 2003
SN  - 0-444-51037-0
SP  - 587
EP  - 623
PB  - Elsevier
CY  - Amsterdam [u.a.]
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
T1  - Chemical and biological field-effect sensors for liquids – a status report
JF  - Handbook of biosensors and biochips / ed. Robert S. Marks ... Bd. 1
Y1  - 2007
SN  - 978-0-470-01905-4
SP  - 395
EP  - 412
PB  - Wiley
CY  - Chichester
ER  - 
TY  - CHAP
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
T1  - Silicon-based chemical and biological field-effect sensors
T2  - Encyclopedia of Sensors. Vol. 9 S - Sk
Y1  - 2006
SN  - 1-58883-065-9
SP  - 463
EP  - 534
PB  - ASP, American Scientific Publ.
CY  - Stevenson Ranch, Calif.
ER  - 
TY  - CHAP
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
T1  - Nanomaterial-Modified Capacitive Field-Effect Biosensors
T2  - Springer Series on Chemical Sensors and Biosensors (Methods and Applications)
N2  - The coupling of charged molecules, nanoparticles, and more generally, inorganic/organic nanohybrids with semiconductor field-effect devices based on an electrolyte–insulator–semiconductor (EIS) system represents a very promising strategy for the active tuning of electrochemical properties of these devices and, thus, opening new opportunities for label-free biosensing by the intrinsic charge of molecules. The simplest field-effect sensor is a capacitive EIS sensor, which represents a (bio-)chemically sensitive capacitor. In this chapter, selected examples of recent developments in the field of label-free biosensing using nanomaterial-modified capacitive EIS sensors are summarized. In the first part, we present applications of EIS sensors modified with negatively charged gold nanoparticles for the label-free electrostatic detection of positively charged small proteins and macromolecules, for monitoring the layer-by-layer formation of oppositely charged polyelectrolyte (PE) multilayers as well as for the development of an enzyme-based biomolecular logic gate. In the second part, examples of a label-free detection by means of EIS sensors modified with a positively charged weak PE layer are demonstrated. These include electrical detection of on-chip and in-solution hybridized DNA (deoxyribonucleic acid) as well as an EIS sensor with pH-responsive weak PE/enzyme multilayers for enhanced field-effect biosensing.
KW  - Biomolecular logic gate
KW  - DNA
KW  - Enzyme biosensor
KW  - Field-effect sensor
KW  - Gold nanoparticle
Y1  - 2017
U6  - http://dx.doi.org/10.1007/5346_2017_2
SP  - 1
EP  - 25
PB  - Springer
CY  - Berlin, Heidelberg
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
T1  - Label-free sensing of biomolecules with field-effect devices for clinical applications
JF  - Electroanalysis
N2  - Among the variety of transducer concepts proposed for label-free detection of biomolecules, the semiconductor field-effect device (FED) is one of the most attractive platforms. As medical techniques continue to progress towards diagnostic and therapies based on biomarkers, the ability of FEDs for a label-free, fast and real-time detection of multiple pathogenic and physiologically relevant molecules with high specificity and sensitivity offers very promising prospects for their application in point-of-care and personalized medicine for an early diagnosis and treatment of diseases. The presented paper reviews recent advances and current trends in research and development of different FEDs for label-free, direct electrical detection of charged biomolecules by their intrinsic molecular charge. The authors are mainly focusing on the detection of the DNA hybridization event, antibody-antigen affinity reaction as well as clinically relevant biomolecules such as cardiac and cancer biomarkers.
Y1  - 2014
U6  - http://dx.doi.org/10.1002/elan.201400073
SN  - 1521-4109 (E-Journal); 1040-0397 (Print)
VL  - 26
IS  - 6
SP  - 1197
EP  - 1213
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
T1  - Capacitive field-effect eis chemical sensors and biosensors: A status report
JF  - Sensors
N2  - Electrolyte-insulator-semiconductor (EIS) field-effect sensors belong to a new generation of electronic chips for biochemical sensing, enabling a direct electronic readout. The review gives an overview on recent advances and current trends in the research and development of chemical sensors and biosensors based on the capacitive field-effect EIS structure—the simplest field-effect device, which represents a biochemically sensitive capacitor. Fundamental concepts, physicochemical phenomena underlying the transduction mechanism and application of capacitive EIS sensors for the detection of pH, ion concentrations, and enzymatic reactions, as well as the label-free detection of charged molecules (nucleic acids, proteins, and polyelectrolytes) and nanoparticles, are presented and discussed.
Y1  - 2020
U6  - http://dx.doi.org/10.3390/s20195639
SN  - 1424-8220
VL  - 20
IS  - 19
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
T1  - Recent progress in silicon-based biologically sensitive field-effect devices
JF  - Current Opinion in Electrochemistry
N2  - Biologically sensitive field-effect devices (BioFEDs) advantageously combine the electronic field-effect functionality with the (bio)chemical receptor’s recognition ability for (bio)chemical sensing. In this review, basic and widely applied device concepts of silicon-based BioFEDs (ion-sensitive field-effect transistor, silicon nanowire transistor, electrolyte-insulator-semiconductor capacitor, light-addressable potentiometric sensor) are presented and recent progress (from 2019 to early 2021) is discussed. One of the main advantages of BioFEDs is the label-free sensing principle enabling to detect a large variety of biomolecules and bioparticles by their intrinsic charge. The review encompasses applications of BioFEDs for the label-free electrical detection of clinically relevant protein biomarkers, deoxyribonucleic acid molecules and viruses, enzyme-substrate reactions as well as recording of the cell acidification rate (as an indicator of cellular metabolism) and the extracellular potential.
Y1  - 2021
U6  - http://dx.doi.org/10.1016/j.coelec.2021.100811
SN  - 2451-9103
IS  - Article number: 100811
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
A1  - Schroth, P.
A1  - Simonis, A.
A1  - Lüth, H.
T1  - An ISFET-based penicillin sensor with high sensitivity, low detection limit and long lifetime
JF  - Sensors and Actuators B. 76 (2001), H. 1-3
Y1  - 2001
SN  - 0925-4005
SP  - 519
EP  - 526
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Thust, M.
A1  - Schroth, P.
A1  - Steffen, A.
A1  - Lüth, H.
A1  - Schöning, Michael Josef
T1  - Penicillin detection by means of silicon-based field-effect structures
JF  - Sensors and Materials. 13 (2001), H. 4
Y1  - 2001
SN  - 0392-2510
SP  - 207
EP  - 223
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Thust, M.
A1  - Schöning, Michael Josef
A1  - Müller-Veggian, Mattea
A1  - Kordos, P.
A1  - Lüth, H.
T1  - Cross-sensitivity of a capacitive penicillin sensor combined with a diffusion barrier
JF  - Sensors and Actuators B. 68 (2000), H. 1-3
Y1  - 2000
SN  - 0925-4005
SP  - 260
EP  - 265
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Wagner, H.
A1  - Schöning, Michael Josef
T1  - Automatisiertes „wafer level“-Testsystem zur Charakterisierung von siliziumbasierten Chemo- und Biosensoren
JF  - Sensoren und Messsysteme 2010 [Elektronische Ressource] : Vorträge der 15. ITG/GMA-Fachtagung vom 18. bis 19. Mai 2010 in Nürnberg / Informationstechnische Gesellschaft im VDE (ITG); VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik (GMA)
Y1  - 2010
SN  - 978-3-8007-3260-9
N1  - Fachtagung Sensoren und Messsysteme 15, 2010, Nürnberg ; Gesellschaft Mess- und Automatisierungstechnik
SP  - 89
EP  - 92
PB  - VDE Verlag
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Wagner, Holger
A1  - Schöning, Michael Josef
T1  - Functional testing and characterisation of (bio-)chemical sensors on wafer level
JF  - Procedia Chemistry. 1 (2009), H. 1
Y1  - 2009
SN  - 1876-6196
N1  - Proceedings of the Eurosensors XXIII conference ; Eurosensors 23
SP  - 835
EP  - 838
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Wagner, Holger
A1  - Schöning, Michael Josef
T1  - Functional testing and characterisation of (bio-)chemical sensors on wafer level
JF  - Sensors and Actuators B: Chemical. 154 (2011), H. 2
Y1  - 2011
SN  - 1873-3077
N1  - EUROSENSORS XXIII
SP  - 169
EP  - 173
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Weil, M.
A1  - Cherstvy, A. G.
A1  - Schöning, Michael Josef
T1  - Electrical monitoring of polyelectrolyte multilayer formation by means of capacitive field-effect devices
JF  - Analytical and bioanalytical chemistry
N2  - The semiconductor field-effect platform represents a powerful tool for detecting the adsorption and binding of charged macromolecules with direct electrical readout. In this work, a capacitive electrolyte–insulator–semiconductor (EIS) field-effect sensor consisting of an Al-p-Si-SiO2 structure has been applied for real-time in situ electrical monitoring of the layer-by-layer formation of polyelectrolyte (PE) multilayers (PEM). The PEMs were deposited directly onto the SiO2 surface without any precursor layer or drying procedures. Anionic poly(sodium 4-styrene sulfonate) and cationic weak polyelectrolyte poly(allylamine hydrochloride) have been chosen as a model system. The effect of the ionic strength of the solution, polyelectrolyte concentration, number and polarity of the PE layers on the characteristics of the PEM-modified EIS sensors have been studied by means of capacitance–voltage and constant-capacitance methods. In addition, the thickness, surface morphology, roughness and wettabilityof the PE mono- and multilayers have been characterised by ellipsometry, atomic force microscopy and water contact-angle methods, respectively. To explain potential oscillations on the gate surface and signal behaviour of the capacitive field-effect EIS sensor modified with a PEM, a simplified electrostatic model that takes into account the reduced electrostatic screening of PE charges by mobile ions within the PEM has been proposed and discussed.
Y1  - 2013
U6  - http://dx.doi.org/10.1007/s00216-013-6951-9
SN  - 1432-1130 ; 1618-2642
VL  - 405
IS  - 20
SP  - 6425
EP  - 6436
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Weil, M. H.
A1  - Bäcker, Matthias
A1  - Mayer, D.
A1  - Schöning, Michael Josef
T1  - Field-effect Devices Functionalised with Gold-Nanoparticle/Macromolecule Hybrids: New Opportunities for a Label-Free Biosensing
JF  - Procedia Engineering
N2  - Field-effect capacitive electrolyte-insulator-semiconductor (EIS) sensors functionalised with citrate-capped gold nanoparticles (AuNP) have been used for the electrostatic detection of macromolecules by their intrinsic molecular charge. The EIS sensor detects the charge changes in the AuNP/macromolecule hybrids induced by the adsorption or binding events. A feasibility of the proposed detection scheme has been exemplary demonstrated by realising EIS sensors for the detection of poly-D-lysine molecules.
Y1  - 2012
U6  - http://dx.doi.org/10.1016/j.proeng.2012.09.136
SN  - 1877-7058
N1  - Part of special issue "26th European Conference on Solid-State Transducers, EUROSENSOR 2012"
IS  - 47
SP  - 273
EP  - 276
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - CHAP
A1  - Poghossian, Arshak
A1  - Weiland, Maryam
A1  - Schöning, Michael Josef
ED  - Lvova, Larisa
ED  - Kirsanov, Dmitry
ED  - di Natale, Corrado
ED  - Legin, Audrey
T1  - Nanoplate field-effect capacitors: a new transducer structure for multiparameter (bio-)chemical sensing
T2  - Multisensor system for chemical analysis : materials and sensors
N2  - An array of electrically isolated nanoplate field-effect silicon-on-insulator (SOI) capacitors as a new transducer structure for multiparameter (bio-)chemical sensing is presented. The proposed approach allows addressable biasing and electrical readout of multiple nanoplate field-effect capacitive (bio-)chemical sensors on the same SOI chip, as well as differential-mode measurements. The realized sensor chip has been applied for pH and penicillin concentration measurements, electrical monitoring of polyelectrolyte multilayer formation, and the label-free electrical detection of consecutive deoxyribonucleic acid (DNA) hybridization and denaturation events.
Y1  - 2014
SN  - 978-981-4411-15-8 ; 978-981-4411-16-5
U6  - http://dx.doi.org/10.1201/b15491-11
SP  - 333
EP  - 373
PB  - Jenny Stanford Publishing
CY  - Singapore
ET  - 1
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Werner, Frederik
A1  - Buniatyan, V. V.
A1  - Wagner, Torsten
A1  - Miamoto, K.
A1  - Yoshinobu, T.
A1  - Schöning, Michael Josef
T1  - Towards addressability of light-addressable potentiometric sensors: Shunting effect of non-illuminated region and cross-talk
JF  - Sensor and Actuators B: Chemical
N2  - The LAPS (light-addressable potentiometric sensor) platform is one of the most attractive approaches for chemical and biological sensing with many applications ranging from pH and ion/analyte concentration measurements up to cell metabolism detection and chemical imaging. However, although it is generally accepted that LAPS measurements are spatially resolved, the light-addressability feature of LAPS devices has not been discussed in detail so far. In this work, an extended electrical equivalent-circuit model of the LAPS has been presented, which takes into account possible cross-talk effects due to the capacitive coupling of the non-illuminated region. A shunting effect of the non-illuminated area on the measured photocurrent and addressability of LAPS devices has been studied. It has been shown, that the measured photocurrent will be determined not only by the local interfacial potential in the illuminated region but also by possible interfacial potential changes in the non-illuminated region, yielding cross-talk effects. These findings were supported by the experimental investigations of a penicillin-sensitive multi-spot LAPS and a metal-insulator-semiconductor LAPS as model systems.
Y1  - 2017
U6  - http://dx.doi.org/10.1016/j.snb.2017.01.047
SN  - 0925-4005
IS  - 244
SP  - 1071
EP  - 1079
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Yoshinobu, T.
A1  - Simonis, A.
A1  - Ecken, H.
A1  - Lüth, H.
A1  - Schöning, Michael Josef
T1  - Penicillin detection by means of field-effect based sensors: EnFET, capacitive EIS sensor or LAPS?
JF  - Proceedings : Copenhagen, Denmark, 27 - 30 August 2000 / [ed.: R. de Reus ...]
Y1  - 2000
SN  - 87-89935-50-0
N1  - Eurosensors ; (14, 2000, København) ; Eurosensors ; (14 : ; 2000.08.27-30 : ; Copenhagen) ; European Conference on Solid-State Transducers ; (14 : ; 2000.08.27-30 : ; Copenhagen)
SP  - 27
EP  - 30
PB  - MIC, Mikroelektronik Centret
CY  - Lyngby, Denmark
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Yoshinobu, Tatsuo
A1  - Schöning, Michael Josef
T1  - Flow-velocity microsensors based on semiconductor field-effect structures
JF  - Sensors. 3 (2003), H. 7
Y1  - 2003
SN  - 1424-8220
SP  - 202
EP  - 212
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Yoshinobu, Tatsuo
A1  - Simonis, A.
A1  - Ecken, H.
A1  - Lüth, Hans
A1  - Schöning, Michael Josef
T1  - Penicillin detection by means of field-effect based sensors: EnFET, capacitive EIS sensor or LAPS?
JF  - Sensors and Actuators B. 78 (2001), H. 1-3
Y1  - 2001
SN  - 0925-4005
SP  - 237
EP  - 242
ER  - 
TY  - JOUR
A1  - Reisert, Steffen
A1  - Geissler, H.
A1  - Florke, R.
A1  - Wagner, P.
A1  - Wagner, Torsten
A1  - Schöning, Michael Josef
T1  - Controlling aseptic sterilization processes by means of a multi-sensor system
Y1  - 2011
N1  - 2011 IEEE Workshop on Merging Fields of Computational Intelligence and Sensor Technology ; 11.-15. April 2011 Paris, France
SP  - 18
EP  - 22
PB  - IEEE
CY  - New York
ER  - 
TY  - CHAP
A1  - Reisert, Steffen
A1  - Geissler, H.
A1  - Flörke, R.
A1  - Weiler, C.
A1  - Wagner, P.
A1  - Schöning, Michael Josef
ED  - Abdelghani, Adnane
ED  - Schöning, Michael Josef
T1  - Characterisation of aseptic sterilisation processes using an electronic nose
T2  - Nanoscale Science and Technology (NS&T´12) : Proceedings Book Humboldt Kolleg ; Tunisia, 17-19 March, 2012
Y1  - 2012
SP  - 45
EP  - 45
ER  - 
TY  - JOUR
A1  - Reisert, Steffen
A1  - Geissler, H.
A1  - Weiler, C.
A1  - Wagner, P.
A1  - Schöning, Michael Josef
T1  - Multiple sensor-type system for monitoring the microbicidal effectiveness of aseptic sterilisation processes
JF  - Food control
N2  - The present work describes a novel multiple sensor-type system for the real-time analysis of aseptic sterilisation processes employing gaseous hydrogen peroxide (H2O2) as a sterilant. The inactivation kinetics of Bacillus atrophaeus by gaseous H2O2 have been investigated by means of a methodical calibration experiment, taking into account the process variables H2O2 concentration, humidity and gas temperature. It has been found that the microbicidal effectiveness at H2O2 concentrations above 2% v/v is largely determined by the concentration itself, while at lower H2O2 concentrations, the gas temperature and humidity play a leading role. Furthermore, the responses of different types of gas sensors towards the influencing factors of the sterilisation process have been analysed within the same experiment. Based on a correlation established between the inactivation kinetics and the sensor responses, a calorimetric H2O2 sensor and a metal-oxide semiconductor (MOX) sensor have been identified as possible candidates for monitoring the microbicidal effectiveness of aseptic sterilisation processes employing gaseous H2O2. Therefore, two linear models that describe the relationship between sensor response and microbicidal effectiveness have been proposed.
Y1  - 2015
U6  - http://dx.doi.org/10.1016/j.foodcont.2014.07.063
SN  - 1873-7129 (E-Journal); 0956-7135 (Print)
VL  - 47
SP  - 615
EP  - 622
ER  - 
TY  - JOUR
A1  - Reisert, Steffen
A1  - Geissler, Hanno
A1  - Flörke, Rudolf
A1  - Näther, Niko
A1  - Wagner, Patrick
A1  - Schöning, Michael Josef
T1  - Towards a multi-sensor system for the evaluation of aseptic processes employing hydrogen peroxide vapour (H2O2)
JF  - Physica status solidi (a) : applications and material science. 208 (2011), H. 6
Y1  - 2011
SN  - 1862-6319
SP  - 1351
EP  - 1356
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Reisert, Steffen
A1  - Geissler, Hanno
A1  - Flörke, Rudolf
A1  - Weiler, Christian
A1  - Wagner, Patrick
A1  - Schöning, Michael Josef
T1  - Characterisation of aseptic sterilisation processes using an electronic nose
JF  - International journal of nanotechnology
Y1  - 2013
SN  - 1475-7435 (Print) 7141-8151 (Online)
VL  - Vol. 10
IS  - No. 5-7
SP  - 470
EP  - 484
PB  - Inderscience Enterprises
CY  - Genève
ER  - 
TY  - JOUR
A1  - Reisert, Steffen
A1  - Henkel, H.
A1  - Schneider, A.
A1  - Schäfer, D.
A1  - Friedrich, P.
A1  - Berger, J.
A1  - Schöning, Michael Josef
T1  - Entwicklung eines Handheld-Sensorsystems für die „On-line“-Messung der H2O2-Konzentration in aseptischen Entkeimungsprozessen
JF  - 9. Dresdner Sensor-Symposium : Dresden, 07.-09. Dezember 2009 / Gerlach, Gerald ; Hauptmann, Peter [Hrsg.]
Y1  - 2009
SN  - 978-3-941298-44-6
N1  - Dresdner Sensor-Symposium ; (9, 2009, Dresden)
SP  - 285
EP  - 288
PB  - TUDpress
CY  - Dresden
ER  - 
TY  - JOUR
A1  - Reisert, Steffen
A1  - Henkel, Hartmut
A1  - Schneider, Andreas
A1  - Schäfer, Daniel
A1  - Friedrich, Peter
A1  - Berger, Jörg
A1  - Schöning, Michael Josef
T1  - Development of a handheld sensor system for the online measurement of hydrogen peroxide in aseptic filling systems
JF  - Physica Status Solidi (A). 207 (2010), H. 4
Y1  - 2010
SN  - 1862-6300
N1  - Special Issue: Engineering of Functional Interfaces EnFI 2009
SP  - 913
EP  - 918
ER  - 
TY  - JOUR
A1  - Reisert, Steffen
A1  - Schneider, Benno
A1  - Geissler, Hanno
A1  - Gompel, Matthias van
A1  - Wagner, Patrick
A1  - Schöning, Michael Josef
T1  - Multi-sensor chip for the investigation of different types of metal oxides for the detection of H2O2 in the ppm range
JF  - physica status solidi (a)
N2  - In this work, a multi-sensor chip for the investigation of the sensing properties of different types of metal oxides towards hydrogen peroxide in the ppm range is presented. The fabrication process and physical characterization of the multi-sensor chip are described. Pure SnO2 and WO3 as well as Pd- and Pt-doped SnO2 films are characterized in terms of their sensitivity to H2O2. The sensing films have been prepared by drop-coating of water-dispensed nano-powders. A physical characterization, including scanning electron microscopy and X-ray diffraction analysis of the deposited metal-oxide films, was done. From the measurements in hydrogen peroxide atmosphere, it could be shown, that all of the tested metal oxide films are suitable for the detection of H2O2 in the ppm range. The highest sensitivity and reproducibility was achieved using Pt-doped SnO2.

Calibration plot of a SnO2, WO3, Pt-, and Pd-doped SnO2 gas sensor for H2O2 concentrations in the ppm range.
Y1  - 2013
SN  - 1862-6319
VL  - 210
IS  - 5
SP  - 898
EP  - 904
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Riedel, Marc
A1  - Kartchemnik, Julia
A1  - Schöning, Michael Josef
A1  - Lisdat, Fred
T1  - Impedimetric DNA detection – steps forward to sensorial application
JF  - Analytical chemistry
N2  - This study describes a label-free impedimetric sensor based on short ssDNA recognition elements for the detection of hybridization events. We concentrate on the elucidation of the influence of target length and recognition sequence position on the sensorial performance. The impedimetric measurements are performed in the presence of the redox system ferri-/ferrocyanide and show an increase in charge transfer resistance upon hybridization of ssDNA to the sensor surface. Investigations on the impedimetric signal stability demonstrate a clear influence of the buffers used during the sensor preparation and the choice of the passivating mercaptoalcanol compound. A stable sensor system has been developed, enabling a reproducible detection of 25mer target DNA in the low nanomolar range. After hybridization, a sensor regeneration can be reached with deionized water by adjustment of effective convection conditions, ensuring a sensor reusability. By investigations of longer targets with overhangs exposed to the solution, we can demonstrate applicability of the impedimetric detection for longer ssDNA. However, a decreasing charge transfer resistance change (ΔRct) is found by extending the overhang. As a strategy to increase the impedance change for longer target strands, the position of the recognition sequence can be designed in a way that a small overhang is exposed to the electrode surface. This is found to result in an increase in the relative Rct change. These results suggest that DNA and consequently negative charge near the electrode possess a larger impact on the impedimetric signal than DNA further away.
Y1  - 2014
U6  - http://dx.doi.org/10.1021/ac501800q
SN  - 1520-6882 (E-Journal); 0003-2700 (Print); 0096-4484 (Print)
VL  - 86 (2014)
IS  - 15
SP  - 7867
EP  - 7874
PB  - ACS Publications
CY  - Columbus
ER  - 
TY  - JOUR
A1  - Riemer, A.
A1  - Schroth, P.
A1  - Schütz, S.
A1  - Hummel, Hans E.
A1  - Lüth, H.
A1  - Kohl, C.-D.
A1  - Schöning, Michael Josef
T1  - The future of fire detection: Biological sensors? – Die Zukunft der Brandgassensorik: Biologische Sensoren?
JF  - Gassensorik in der Brandmeldetechnik : [VdS-Fachtagung, am 15. und 16. November 2000 in Köln] = Gas sensors for fire detection / VdS Schadenverhütung
Y1  - 2000
N1  - Fachtagung Gassensorik in der Brandmeldetechnik ; (2000, Köln)
SP  - 1
EP  - 7
PB  - VdS Schadenverhütung
CY  - Köln
ER  - 
TY  - JOUR
A1  - Rodrigues, Raul T.
A1  - Morais, Paulo V.
A1  - Nordi, Cristina S. F.
A1  - Schöning, Michael Josef
A1  - Siqueira Jr., José R.
A1  - Caseli, Luciano
T1  - Carbon Nanotubes and Algal Polysaccharides To Enhance the Enzymatic Properties of Urease in Lipid Langmuir-Blodgett Films
JF  - Langmuir
N2  - Algal polysaccharides (extracellular polysaccharides) and carbon nanotubes (CNTs) were adsorbed on dioctadecyldimethylammonium bromide Langmuir monolayers to serve as a matrix for the incorporation of urease. The physicochemical properties of the supramolecular system as a monolayer at the air–water interface were investigated by surface pressure–area isotherms, surface potential–area isotherms, interfacial shear rheology, vibrational spectroscopy, and Brewster angle microscopy. The floating monolayers were transferred to hydrophilic solid supports, quartz, mica, or capacitive electrolyte–insulator–semiconductor (EIS) devices, through the Langmuir–Blodgett (LB) technique, forming mixed films, which were investigated by quartz crystal microbalance, fluorescence spectroscopy, and field emission gun scanning electron microscopy. The enzyme activity was studied with UV–vis spectroscopy, and the feasibility of the thin film as a urea sensor was essayed in an EIS sensor device. The presence of CNT in the enzyme–lipid LB film not only tuned the catalytic activity of urease but also helped to conserve its enzyme activity. Viability as a urease sensor was demonstrated with capacitance–voltage and constant capacitance measurements, exhibiting regular and distinctive output signals over all concentrations used in this work. These results are related to the synergism between the compounds on the active layer, leading to a surface morphology that allowed fast analyte diffusion owing to an adequate molecular accommodation, which also preserved the urease activity. This work demonstrates the feasibility of employing LB films composed of lipids, CNT, algal polysaccharides, and enzymes as EIS devices for biosensing applications.
Y1  - 2018
U6  - http://dx.doi.org/10.1021/acs.langmuir.7b04317
SN  - 1520-5827
VL  - 34
IS  - 9
SP  - 3082
EP  - 3093
PB  - ACS Publications
CY  - Washington, DC
ER  - 
TY  - JOUR
A1  - Rolka, David
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
T1  - Integration of a capacitive EIS sensor into a FIA system for pH and penicillin determination
JF  - Sensors. 4 (2004)
Y1  - 2004
SN  - 1424-8220
SP  - 84
EP  - 94
ER  - 
TY  - JOUR
A1  - Röhlen, Desiree
A1  - Pilas, Johanna
A1  - Dahmen, Markus
A1  - Keusgen, Michael
A1  - Selmer, Thorsten
A1  - Schöning, Michael Josef
T1  - Toward a Hybrid Biosensor System for Analysis of Organic and Volatile Fatty Acids in Fermentation Processes
JF  - Frontiers in Chemistry
N2  - Monitoring of organic acids (OA) and volatile fatty acids (VFA) is crucial for the control of anaerobic digestion. In case of unstable process conditions, an accumulation of these intermediates occurs. In the present work, two different enzyme-based biosensor arrays are combined and presented for facile electrochemical determination of several process-relevant analytes. Each biosensor utilizes a platinum sensor chip (14 × 14 mm²) with five individual working electrodes. The OA biosensor enables simultaneous measurement of ethanol, formate, d- and l-lactate, based on a bi-enzymatic detection principle. The second VFA biosensor provides an amperometric platform for quantification of acetate and propionate, mediated by oxidation of hydrogen peroxide. The cross-sensitivity of both biosensors toward potential interferents, typically present in fermentation samples, was investigated. The potential for practical application in complex media was successfully demonstrated in spiked sludge samples collected from three different biogas plants. Thereby, the results obtained by both of the biosensors were in good agreement to the applied reference measurements by photometry and gas chromatography, respectively. The proposed hybrid biosensor system was also used for long-term monitoring of a lab-scale biogas reactor (0.01 m³) for a period of 2 months. In combination with typically monitored parameters, such as gas quality, pH and FOS/TAC (volatile organic acids/total anorganic carbonate), the amperometric measurements of OA and VFA concentration could enhance the understanding of ongoing fermentation processes.
Y1  - 2018
U6  - http://dx.doi.org/10.3389/fchem.2018.00284
IS  - 6
PB  - Frontiers
CY  - Lausanne
ER  - 
TY  - JOUR
A1  - Röhlen, Desiree
A1  - Pilas, Johanna
A1  - Schöning, Michael Josef
A1  - Selmer, Thorsten
T1  - Development of an amperometric biosensor platform for the combined determination of l-Malic, Fumaric, and l-Aspartic acid
JF  - Applied Biochemistry and Biotechnology
N2  - Three amperometric biosensors have been developed for the detection of L-malic acid, fumaric acid, and L -aspartic acid, all based on the combination of a malate-specific dehydrogenase (MDH, EC 1.1.1.37) and diaphorase (DIA, EC 1.8.1.4). The stepwise expansion of the malate platform with the enzymes fumarate hydratase (FH, EC 4.2.1.2) and aspartate ammonia-lyase (ASPA, EC 4.3.1.1) resulted in multi-enzyme reaction cascades and, thus, augmentation of the substrate spectrum of the sensors. Electrochemical measurements were carried out in presence of the cofactor β-nicotinamide adenine dinucleotide (NAD+) and the redox mediator hexacyanoferrate (III) (HCFIII). The amperometric detection is mediated by oxidation of hexacyanoferrate (II) (HCFII) at an applied potential of + 0.3 V vs. Ag/AgCl. For each biosensor, optimum working conditions were defined by adjustment of cofactor concentrations, buffer pH, and immobilization procedure. Under these improved conditions, amperometric responses were linear up to 3.0 mM for L-malate and fumarate, respectively, with a corresponding sensitivity of 0.7 μA mM−1 (L-malate biosensor) and 0.4 μA mM−1 (fumarate biosensor). The L-aspartate detection system displayed a linear range of 1.0–10.0 mM with a sensitivity of 0.09 μA mM−1. The sensor characteristics suggest that the developed platform provides a promising method for the detection and differentiation of the three substrates.
Y1  - 2017
U6  - http://dx.doi.org/10.1007/s12010-017-2578-1
SN  - 1559-0291
VL  - 183
SP  - 566
EP  - 581
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Schmitt, G.
A1  - Faßbender, F.
A1  - Lüth, H.
A1  - Schöning, Michael Josef
A1  - Buss, G.
A1  - Kranzmann, A.
A1  - Gramberg, U.
T1  - Korrosionsschutzwirkung von Passivierungsschichten am Beispiel eines Mikroelektrodenarrays
JF  - Werkstoffe für die Energietechnik / Symposium 3
Y1  - 1999
SN  - 3-527-29940-8
N1  - Serie Werkstoffwoche '98 ; 3
SP  - 345
EP  - 350
PB  - Wiley-VCH
CY  - Weinheim [u.a.]
ER  - 
TY  - JOUR
A1  - Schmitt, G.
A1  - Faßbender, F.
A1  - Lüth, H.
A1  - Schöning, Michael Josef
A1  - Schultze, J. W.
A1  - Buß, G.
T1  - Passivation and corrosion of microelectrode arrays
JF  - Materials and Corrosion. 51 (2000), H. 1
Y1  - 2000
SN  - 0947-5117
SP  - 20
EP  - 25
ER  - 
TY  - JOUR
A1  - Schmitt, G.
A1  - Schultze, J.-W.
A1  - Faßbender, F.
A1  - Buß, G.
A1  - Lüth, H.
A1  - Schöning, Michael Josef
T1  - Passivation and corrosion of microelectrode arrays
JF  - Electrochimica Acta. 44 (1999), H. 21-22
Y1  - 1999
SN  - 0013-4686
SP  - 3865
EP  - 3883
ER  - 
TY  - JOUR
A1  - Schmitt, G.
A1  - Werner, C.
A1  - Schöning, Michael Josef
T1  - Microelectrochemical efficiency evaluation of inhibitors for CO2 corrosion of carbon steel under high shear stress gradients
JF  - Corrosion 2002. Conference Proceedings. NACExpo, 57th Annual Conference and Exhibition, Denver, US, Apr 7-11, 2002
Y1  - 2002
N1  - Paper 02280
SP  - 1
EP  - 11
PB  - NACE International
CY  - Houston, Texas
ER  - 
TY  - JOUR
A1  - Scholl, Fabio
A1  - Morais, Paulo
A1  - Gabriel, Rayla
A1  - Schöning, Michael Josef
A1  - Siqueira, Jose Roberto, Jr.
A1  - Caseli, Luciano
T1  - Carbon nanotubes arranged as smart interfaces in lipid Langmuir-Blodgett films enhancing the enzymatic properties of penicillinase for biosensing applications
JF  - Applied Materials & Interfaces
N2  - In this paper, carbon nanotubes (CNTs) were incorporated in penicillinase-phospholipid Langmuir and Langmuir–Blodgett (LB) films to enhance the enzyme catalytic properties. Adsorption of the penicillinase and CNTs at dimyristoylphosphatidic acid (DMPA) monolayers at the air–water interface was investigated by surface pressure–area isotherms, vibrational spectroscopy, and Brewster angle microscopy. The floating monolayers were transferred to solid supports through the LB technique, forming mixed DMPA-CNTs-PEN films, which were investigated by quartz crystal microbalance, vibrational spectroscopy, and atomic force microscopy. Enzyme activity was studied with UV–vis spectroscopy and the feasibility of the supramolecular device nanostructured as ultrathin films were essayed in a capacitive electrolyte–insulator–semiconductor (EIS) sensor device. The presence of CNTs in the enzyme–lipid LB film not only tuned the catalytic activity of penicillinase but also helped conserve its enzyme activity after weeks, showing increased values of activity. Viability as penicillin sensor was demonstrated with capacitance/voltage and constant capacitance measurements, exhibiting regular and distinctive output signals over all concentrations used in this work. These results may be related not only to the nanostructured system provided by the film, but also to the synergism between the compounds on the active layer, leading to a surface morphology that allowed a fast analyte diffusion because of an adequate molecular accommodation, which also preserved the penicillinase activity. This work therefore demonstrates the feasibility of employing LB films composed of lipids, CNTs, and enzymes as EIS devices for biosensing applications.
Y1  - 2017
U6  - http://dx.doi.org/10.1021/acsami.7b08095
SN  - 1944-8252
VL  - 9
IS  - 36
SP  - 31054
EP  - 31066
PB  - ACS
CY  - Washington
ER  - 
TY  - JOUR
A1  - Schroth, P.
A1  - Lüth, H.
A1  - Hummel, Hans E.
A1  - Schütz, S.
A1  - Schöning, Michael Josef
T1  - Characterising an insect antenna as a receptor for a biosensor by means of impedance spectroscopy
JF  - Scaling down in electrochemistry : electrochemical micro- and nanosystem technology ; proceedings of the 3rd International Symposium on Electrochemical Microsystem Technologies, Garmisch-Patenkirchen, Germany, 11 - 15 September 2000 / ed. by J. W. Schultz
Y1  - 2001
SN  - 0-08-044014-2
SP  - 293
EP  - 297
PB  - Elsevier [u.a.]
CY  - Amsterdam [u.a.]
ER  - 
TY  - JOUR
A1  - Schroth, P.
A1  - Schöning, Michael Josef
A1  - Kordos, P.
A1  - Lüth, H.
A1  - Schütz, S.
A1  - Weißbecker, B.
A1  - Hummel, Hans E.
T1  - Insectbased BioFETs with improved signal characteristics
JF  - Biosensors & Bioelectronics. 14 (1999), H. 3
Y1  - 1999
SN  - 0956-5663
SP  - 303
EP  - 308
ER  - 
TY  - JOUR
A1  - Schroth, P.
A1  - Schöning, Michael Josef
A1  - Lüth, H.
A1  - Weißbecker, B.
A1  - Hummel, Hans E.
A1  - Schütz, S.
T1  - Extending the capabilities of an antenna/chip biosensor by employing various insect species
JF  - Sensors and  Actuators B. 78 (2001), H. 1-3
Y1  - 2001
SN  - 0925-4005
SP  - 1
EP  - 5
ER  - 
TY  - JOUR
A1  - Schroth, P.
A1  - Schöning, Michael Josef
A1  - Lüth, H.
A1  - Weißbecker, B.
A1  - Hummel, Hans E.
A1  - Schütz, S.
T1  - Extending the capabilities of an antenna/chip biosensor by employing various insect species
JF  - Proceedings : Copenhagen, Denmark, 27 - 30 August 2000 / [ed.: R. de Reus ...]
Y1  - 2000
SN  - 87-89935-50-0
N1  - Eurosensors ; (14, 2000, København) ; Eurosensors ; (14 : ; 2000.08.27-30 : ; Copenhagen) ; European Conference on Solid-State Transducers ; (14 : ; 2000.08.27-30 : ; Copenhagen)
SP  - 27
EP  - 30
PB  - MIC, Mikroelektronik Centret
CY  - Lyngby, Denmark
ER  - 
TY  - JOUR
A1  - Schroth, P.
A1  - Schöning, Michael Josef
A1  - Schütz, S.
A1  - Epanya, P.
A1  - Steffen, A.
A1  - Weißbecker, B.
A1  - Hummel, Hans E.
A1  - Kordos, P.
A1  - Lüth, H.
T1  - Improving the bioelectronic interface of an antenna/chip biosensor – technological aspects
JF  - Proceedings : The Hague, The Netherlands, September 12 - 15, 1999 / [ed. by M. Bartek]. Vol 1.
Y1  - 1999
SN  - 90-76699-02-X
N1  - Eurosensors ; (13, 1999, 's-Gravenhage) ; Eurosensors ; (13 : ; 1999.09.12-15 : ; The Hague) ; European Conference on Solid-State Transducers ; (13 : ; 1999.09.12-15 : ; The Hague)
SP  - 569
EP  - 572
CY  - The Hague, The Netherlands
ER  - 
TY  - JOUR
A1  - Schroth, P.
A1  - Schöning, Michael Josef
A1  - Schütz, S.
A1  - Malkoc, Ü.
A1  - Steffen, A.
A1  - Marso, M.
A1  - Hummel, Hans E.
A1  - Kordos, P.
A1  - Lüth, H.
T1  - Coupling of insect antennae to field-effect transistors for biochemical sensing
JF  - Electrochimica Acta. 44 (1999), H. 21-22
Y1  - 1999
SN  - 0013-4686
SP  - 3821
EP  - 3826
ER  - 
TY  - JOUR
A1  - Schroth, P.
A1  - Schöning, Michael Josef
A1  - Schütz, S.
A1  - Steffen, A.
A1  - Weißbecker, B.
A1  - Hummel, Hans E.
A1  - Kordos, P.
A1  - Lüth, H.
T1  - Nachweis von organischen Duftstoffen durch Biosensoren auf der Basis von Insektenantennen
JF  - Gesellschaft Mess- und Automatisierungstechnik: Sensoren und Meßsysteme 2000 : Tagung Ludwigsburg, 13. und 14. März 2000 / VDI/VDE-Gesellschaft Meß- und Automatisierungstechnik
Y1  - 2000
SN  - 3-18-091530-7
N1  - VDI-Berichte; 1530
SP  - 107
EP  - 114
PB  - VDI-Verl.
CY  - Düsseldorf:
ER  - 
TY  - JOUR
A1  - Schroth, P.
A1  - Weißbecker, B.
A1  - Schütz, S.
A1  - Ecken, H.
A1  - Yoshinobu, T.
A1  - Lüth, H.
A1  - Schöning, Michael Josef
T1  - Bioelectronic signal processing - intact chemoreceptors coupled to field-effect devices
JF  - Lecture Notes of the ICB Seminars
Y1  - 2002
SP  - 28
EP  - 42
PB  - MCB
CY  - Warsaw
ER  - 
TY  - JOUR
A1  - Schroth, P.
A1  - Weißbecker, B.
A1  - Schütz, S.
A1  - Ecken, H.
A1  - Yoshinobu, T.
A1  - Lüth, H.
A1  - Schöning, Michael Josef
T1  - Bioelectronic signal processing - intact chemoreceptors coupled to field-effect devices
JF  - Biocybernetics and Biomedical Engineering. 21 (2001), H. 3
Y1  - 2001
SN  - 0208-5216
SP  - 27
EP  - 42
ER  - 
TY  - JOUR
A1  - Schubert, J.
A1  - Schöning, Michael Josef
A1  - Mourzina, Y. G.
A1  - Legin, A. V.
A1  - Vlasov, Y. G.
A1  - Zander, W.
A1  - Lüth, H.
T1  - Multicomponent thin films for electrochemical sensor applications prepared by pulsed laser deposition
JF  - Sensors and Actuators B. 76 (2001), H. 1-3
Y1  - 2001
SN  - 0925-4005
SP  - 327
EP  - 330
ER  - 
TY  - JOUR
A1  - Schubert, J.
A1  - Schöning, Michael Josef
A1  - Schmidt, C.
A1  - Siegert, M.
A1  - Mesters, S.
A1  - Zander, W.
A1  - Kordos, P.
A1  - Lüth, H.
A1  - Legin, A.
A1  - Mourzina, Y. G.
A1  - Seleznev, B.
A1  - Vlasov, Y. G.
T1  - Chalcogenide-based thin film sensors prepared by pulsed laser deposition technique
JF  - Applied Physics A. 69, (1999), H. Supplement 1
Y1  - 1999
SN  - 0947-8396
U6  - http://dx.doi.org/10.1007/s003390051534
SP  - 803
EP  - 805
ER  - 
TY  - JOUR
A1  - Schusser, Sebastian
A1  - Bäcker, Matthias
A1  - Krischer, M.
A1  - Wenzel, L.
A1  - Leinhos, Marcel
A1  - Poghossian, Arshak
A1  - Biselli, Manfred
A1  - Wagner, P.
A1  - Schöning, Michael Josef
T1  - Enzymatically catalyzed degradation of biodegradable polymers investigated by means of a semiconductor-based field-effect sensor
JF  - Procedia Engineering
N2  - A semiconductor field-effect device has been used for an enzymatically catalyzed degradation of biopolymers for the first time. This novel technique is capable to monitor the degradation process of multiple samples in situ and in real-time. As model system, the degradation of the biopolymer poly(D, L-lactic acid) has been monitored in the degradation medium containing the enzyme lipase from Rhizomucor miehei. The obtained results demonstrate the potential of capacitive field-effect sensors for degradation studies of biodegradable polymers.
KW  - Field-effect sensor
KW  - enzymatic (bio)degradation
KW  - poly(d, l-lactic acid)
KW  - in-situ monitoring
KW  - impedance spectroscopy
Y1  - 2014
U6  - http://dx.doi.org/10.1016/j.proeng.2014.11.689
SN  - 1877-7058
N1  - EUROSENSORS 2014 ; European Conference on Solid-State Transducers <28, 2014>
VL  - 87
SP  - 1314
EP  - 1317
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - CHAP
A1  - Schusser, Sebastian
A1  - Bäcker, Matthias
A1  - Leinhos, Marcel
A1  - Krischer, M.
A1  - Wenzel, L.
A1  - Poghossian, Arshak
A1  - Wagner, Patrick
A1  - Schöning, Michael Josef
T1  - Sensorkonzept zur in vitro Echtzeitmessung des Degradationsverhaltens von biodegradierbaren Biopolymeren
T2  - 11. Dresdner Sensor-Symposium : 9.-11.12.2013
Y1  - 2013
SN  - 978-3-9813484-5-3
SP  - 174
EP  - 177
ER  - 
TY  - JOUR
A1  - Schusser, Sebastian
A1  - Krischer, M.
A1  - Molin, D. G. M.
A1  - Akker, N. M. S. van den
A1  - Bäcker, Matthias
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
T1  - Sensor System for in-situ and Real-time Monitoring of Polymer (bio) degradation
JF  - Procedia Engineering
N2  - A sensor system for investigating (bio)degradationprocesses of polymers is presented. The system utilizes semiconductor field-effect sensors and is capable of monitoring the degradation process in-situ and in real-time. The degradation of the polymer poly(d,l-lactic acid) is exemplarily monitored in solutions with different pH value, pH-buffer solution containing the model enzyme lipase from Rhizomucormiehei and cell-culture medium containing supernatants from stimulated and non-stimulated THP-1-derived macrophages mimicking activation of the immune system.
Y1  - 2015
U6  - http://dx.doi.org/10.1016/j.proeng.2015.08.815
SN  - 1877-7058
N1  - Eurosensors 2015
VL  - 120
SP  - 948
EP  - 951
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Schusser, Sebastian
A1  - Krischer, Maximillian
A1  - Bäcker, Matthias
A1  - Poghossian, Arshak
A1  - Wagner, Patrick
A1  - Schöning, Michael Josef
T1  - Monitoring of the Enzymatically Catalyzed Degradation of Biodegradable Polymers by Means of Capacitive Field-Effect Sensors
JF  - Analytical Chemistry
N2  - Designing novel or optimizing existing biodegradable polymers for biomedical applications requires numerous tests on the effect of substances on the degradation process. In the present work, polymer-modified electrolyte–insulator–semiconductor (PMEIS) sensors have been applied for monitoring an enzymatically catalyzed degradation of polymers for the first time. The thin films of biodegradable polymer poly(d,l-lactic acid) and enzyme lipase were used as a model system. During degradation, the sensors were read-out by means of impedance spectroscopy. In order to interpret the data obtained from impedance measurements, an electrical equivalent circuit model was developed. In addition, morphological investigations of the polymer surface have been performed by means of in situ atomic force microscopy. The sensor signal change, which reflects the progress of degradation, indicates an accelerated degradation in the presence of the enzyme compared to hydrolysis in neutral pH buffer media. The degradation rate increases with increasing enzyme concentration. The obtained results demonstrate the potential of PMEIS sensors as a very promising tool for in situ and real-time monitoring of degradation of polymers.
Y1  - 2015
U6  - http://dx.doi.org/10.1021/acs.analchem.5b00617
SN  - 1520-6882
VL  - 87
IS  - 13
SP  - 6607
EP  - 6613
PB  - ACS Publications
CY  - Washington, DC
ER  - 
TY  - JOUR
A1  - Schusser, Sebastian
A1  - Leinhos, Marcel
A1  - Bäcker, Matthias
A1  - Poghossian, Arshak
A1  - Wagner, Patrick
A1  - Schöning, Michael Josef
T1  - Impedance spectroscopy: A tool for real-time in situ monitoring of the degradation of biopolymers
JF  - Physica Status Solidi (A)
N2  - Investigation of the degradation kinetics of biodegradable polymers is essential for the development of implantable biomedical devices with predicted biodegradability. In this work, an impedimetric sensor has been applied for real-time and in situ monitoring of degradation processes of biopolymers. The sensor consists of two platinum thin-film electrodes covered by a polymer film to be studied. The benchmark biomedical polymer poly(D,L-lactic acid) (PDLLA) was used as a model system. PDLLA films were deposited on the sensor structure from a polymer solution by using the spin-coating method. The degradation kinetics of PDLLA films have been studied in alkaline solutions of pH 9 and 12 by means of an impedance spectroscopy (IS) method. Any changes in a polymer capacitance/resistance induced by water uptake and/or polymer degradation will modulate the global impedance of the polymer-covered sensor that can be used as an indicator of the polymer degradation. The degradation rate can be evaluated from the time-dependent impedance spectra. As expected, a faster degradation has been observed for PDLLA films exposed to pH 12 solution.
Y1  - 2013
U6  - http://dx.doi.org/10.1002/pssa.201200941
SN  - 1521-396X ; 0031-8965
VL  - 210
IS  - 5
SP  - 905
EP  - 910
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - CHAP
A1  - Schusser, Sebastian
A1  - Leinhos, Marcel
A1  - Poghossian, Arshak
A1  - Wagner, Patrick
A1  - Schöning, Michael Josef
ED  - Abdelghani, Adnane
ED  - Schöning, Michael Josef
T1  - Biopolymer-degradation monitoring by chip-­based impedance spectroscopy technique
T2  - Nanoscale Science and Technology (NS&T´12) : Proceedings Book Humboldt Kolleg ; Tunisia, 17-19 March, 2012
Y1  - 2012
SP  - 47
EP  - 47
ER  - 
TY  - JOUR
A1  - Schusser, Sebastian
A1  - Menzel, S.
A1  - Bäcker, Matthias
A1  - Leinhos, Marcel
A1  - Poghossian, Arshak
A1  - Wagner, P.
A1  - Schöning, Michael Josef
T1  - Degradation of thin poly(lactic acid) films: characterization by capacitance-voltage, atomic force microscopy, scanning electron microscopy and contact-angle measurements
JF  - Electrochimica Acta
Y1  - 2013
SN  - 1873-3859 (E-Journal); 0013-4686 (Print)
VL  - Vol. 113
SP  - 779
EP  - 784
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Schusser, Sebastian
A1  - Poghossian, Arshak
A1  - Bäcker, Matthias
A1  - Krischer, M.
A1  - Leinhos, Marcel
A1  - Wagner, P.
A1  - Schöning, Michael Josef
T1  - An application of field-effect sensors for in-situ monitoring of degradation of biopolymers
JF  - Sensors and actuators B: Chemical
N2  - The characterization of the degradation kinetics of biodegradable polymers is mandatory with regard to their proper application. In the present work, polymer-modified electrolyte–insulator–semiconductor (PMEIS) field-effect sensors have been applied for in-situ monitoring of the pH-dependent degradation kinetics of the commercially available biopolymer poly(d,l-lactic acid) (PDLLA) in buffer solutions from pH 3 to pH 13. PDLLA films of 500 nm thickness were deposited on the surface of an Al–p-Si–SiO2–Ta2O5 structure from a polymer solution by means of spin-coating method. The PMEIS sensor is, in principle, capable to detect any changes in bulk, surface and interface properties of the polymer induced by degradation processes. A faster degradation has been observed for PDLLA films exposed to alkaline solutions (pH 9, pH 11 and pH 13).
Y1  - 2015
U6  - http://dx.doi.org/10.1016/j.snb.2014.10.058
SN  - 1873-3077 (E-Journal); 0925-4005 (Print)
VL  - 207, Part B
SP  - 954
EP  - 959
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Schusser, Sebastian
A1  - Poghossian, Arshak
A1  - Bäcker, Matthias
A1  - Leinhos, Marcel
A1  - Wagner, Patrick
A1  - Schöning, Michael Josef
T1  - Characterization of biodegradable polymers with capacitive field-effect sensors
JF  - Sensors and actuators B: Chemical
N2  - In vitro studies of the degradation kinetic of biopolymers are essential for the design and optimization of implantable biomedical devices. In the presented work, a field-effect capacitive sensor has been applied for the real-time and in situ monitoring of degradation processes of biopolymers for the first time. The polymer-covered field-effect sensor is, in principle, capable to detect any changes in bulk, surface and interface properties of the polymer induced by degradation processes. The feasibility of this approach has been experimentally proven by using the commercially available biomedical polymer poly(D,L-lactic acid) (PDLLA) as a model system. PDLLA films of different thicknesses were deposited on the Ta₂O₅-gate surface of the field-effect structure from a polymer solution by means of spin-coating method. The polymer-modified field-effect sensors have been characterized by means of capacitance–voltage and impedance-spectroscopy method. The degradation of the PDLLA was accelerated by changing the degradation medium from neutral (pH 7.2) to alkaline (pH 9) condition, resulting in drastic changes in the capacitance and impedance spectra of the polymer-modified field-effect sensor.
KW  - Impedance spectroscopy
KW  - C–V method
KW  - Real-time monitoring
KW  - Poly(d,l-lacticacid)
KW  - (Bio)degradation
KW  - Field-effect sensor
Y1  - 2012
U6  - http://dx.doi.org/10.1016/j.snb.2012.07.099
SN  - 0925-4005
N1  - Part of special issue "Selected Papers from the 14th International Meeting on Chemical Sensors"
VL  - 187
SP  - 2
EP  - 7
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
T1  - Silicon-based biochemical sensors
JF  - CNI - The Center of Nanoelectronic Systems for Information Technology
Y1  - 2003
SP  - 165
EP  - 170
PB  - Foschungszentrum Jülich
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
T1  - Novel approaches to design siliconbased field-effect sensors
JF  - Electrochemical Microsystem Technologies, New Trends in Electrochemistry Vol. 2
Y1  - 2002
SP  - 384
EP  - 408
PB  - Taylor & Francis
CY  - London New York
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
T1  - Feldeffektstrukturen mit AgI-Aufdampfschichten als chemische Sensoren
JF  - KfK-Bericht. 5195 (1993)
Y1  - 1993
SN  - 0303-4003
SP  - 1
EP  - 95
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
T1  - "Playing around“ with field-effect sensors on the basis of EIS structures, LAPS and ISFETs
JF  - Sensors. 5 (2005), H. 3
Y1  - 2005
SN  - 1424-8220
SP  - 126
EP  - 138
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
T1  - "Voltohmmetry" – a new transducer principle for electrochemical sensors
JF  - Ultrathin electrochemical chemo- and biosensors : technology and performance / Vladimir M. Mirsky
Y1  - 2004
SN  - 3-540-21285-X
SP  - 117
EP  - 140
PB  - Springer
CY  - Berlin [u.a.]
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
T1  - Microelectronics contacts (bio-)chemistry – Semiconductor-based sensors
JF  - Biologi Italiani. 8 (2001)
Y1  - 2001
SN  - 0392-2510
SP  - 5
EP  - 10
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
T1  - Silicon-based field-effect structures – From dielectrics to bioelectronics
JF  - Dielectrics in emerging technologies : proceedings of the international symposium ; [papers presented at the First International Symposium on Science and Technology of Dielectrics in Emerging Fields held from 27th April to 2nd May 2003 in Paris, France] / sponsoring divisions: Dielectric Science and Technology, Electronics. Ed.: D. Misra.
Y1  - 2003
SN  - 1-56677-346-6
N1  - International Symposium on Science and Technology of Dielectrics in Emerging Fields ; (1, 2003, Paris)
SP  - 31
EP  - 37
PB  - Electrochemical Society
CY  - Pennington, NJ
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
T1  - Silicon recognizes biochemical parameters: Microchips for analytical sensor applications
JF  - American Laboratory. 32 (2000), H. 16
Y1  - 2000
SN  - 0044-7749
SP  - 24
EP  - 31
ER  - 
TY  - CHAP
A1  - Schöning, Michael Josef
A1  - Abdelghani, Adnane
T1  - Advancements in Nanotechnology and Microelectronics (ANM '09) <2009, Tunisia>: Proceedings book ; Tunisia, November, 13 & 14, 2009 / Humboldt Kolleg. Ed. by Michael J. Schöning ; Adnane Abdelghani
N2  - The ANM’09 multi-disciplinary scientific program includes topics in the fields of "Nanotechnology and Microelectronics" ranging from "Bio/Micro/Nano Materials and Interfacing" aspects, "Chemical and Bio-Sensors", "Magnetic and Superconducting Devices", "MEMS and Microfluidics" over "Theoretical Aspects, Methods and Modelling" up to the important bridging "Academics meet Industry".
KW  - Nanopartikel
KW  - Biosensor
KW  - Supraleiter
KW  - MEMS
KW  - Biophoton
KW  - Nanotechnology ; Microelectronics ; Biosensors ; Superconductor ; MEMS
Y1  - 2009
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:a96-opus-3113
ER  - 
TY  - CHAP
A1  - Schöning, Michael Josef
A1  - Abdelghani, Adnane
T1  - Nanoscale Science and Technology (NS&T’12) : Proceedings Book Humboldt Kolleg <2012, Tunisia>  ; Tunisia, 17-19 March, 2012 / ed. by Michael J. Schöning ; Adnane Abdelghani
N2  - Proceedings of the 2nd Humboldt Kolleg, Hammamet, Tunisia Organizer: Alexander von Humboldt Stiftung, Germany. pdf 184 p. Welcome Address Dear Participants, Welcome to the 2nd Humboldt Kolleg in “Nanoscale Science and Technology” (NS&T’12) in Tunisia, sponsored by the "Alexander von Humboldt" foundation. The NS&T’12 multidisciplinary scientific program includes seven "hot" topics dealing with "Nanoscale Science and Technology" covering basic and application-oriented research as well as industrial (market) aspects: - Molecular Biophyics, Spectroscopy Techniques, Imaging Microscopy - Nanomaterials Synthesis for Medicine and Bio-chemical Sensors - Nanostructures, Semiconductors, Photonics and Nanodevices - New Technologies in Market Industry - Environment, Electro-chemistry, Bio-polymers and Fuel Cells - Nanomaterials, Photovoltaic, Modelling, Quantum Physics - Microelectronics, Sensors Networks and Embedded Systems We are deeply indebted to all members of the Scientific Committee and General Chairs for joint Sessions and to all speakers and chairmen, who have dedicated invaluable time and efforts for the realization of this event. On behalf of the Organizing Committee, we are cordially inviting you to join the conference and hope that your stay will be fruitful, rewarding and enjoyable. Prof. Dr. Michael J. Schöning, Prof. Dr. Adnane Abdelghani
KW  - Biosensor
KW  - Nanotechnologie
KW  - Nanomaterial
KW  - Nano Materials
KW  - Bio-Sensors
Y1  - 2012
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:a96-opus-3544
ER  - 
TY  - CHAP
A1  - Schöning, Michael Josef
A1  - Abouzar, Maryam H.
A1  - Han, Y.
A1  - Ingebrandt, S.
A1  - Offenhäusser, A.
A1  - Poghossian, Arshak
T1  - Markierungsfreie DNA-Detektion mit Silizium-Feldeffektsensoren – Messeffekte oder Artefakte?
T2  - Sensoren und Mess-Systeme 2006 : Vorträge der 13. ITG/GMA-Fachtagung vom 13. bis 14.3.2006 in Freiburg/Breisgau
Y1  - 2006
SN  - 3-8007-2939-3
SP  - 443
EP  - 446
PB  - VDE Verl.
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Abouzar, Maryam H.
A1  - Ingebrandt, Sven
A1  - Platen, Johannes
A1  - Offenhäusser, Andreas
A1  - Poghossian, Arshak
ED  - Comini, Elisabetta
T1  - Towards label-free detection of charged macromolecules using field-effect-based structures : Scaling down from capacitive EIS sensor over ISFET to nano-scale devices
JF  - Nanostructured materials and hybrid composites for gas sensors and biomedical applications : symposium held April 18-20, 2006, San Francisco , California, U.S.A.
Y1  - 2006
SN  - 9781558998711
IS  - paper 0915-R05-04
SP  - 89
EP  - 94
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Abouzar, Maryam H.
A1  - Poghossian, Arshak
T1  - pH and ion sensitivity of a field-effect EIS (electrolyte-insulator-semiconductor) sensor covered with polyelectrolyte multilayers
JF  - Journal of Solid State Electrochemistry. 13 (2009), H. 1
Y1  - 2009
SN  - 1433-0768
N1  - This manuscript is an invited paper to the special issue on “Solid-state potentiometric sensors” (Guest editor: Johan Bobacka).
SP  - 115
EP  - 122
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Abouzar, Maryam H.
A1  - Poghossian, Arshak
A1  - Han, Yinhua
A1  - Offenhäusser, Andreas
A1  - Ingebrandt, Sven
T1  - Markierungsfreie DNA-Detektion mit Silizium-Feldeffekt-Sensoren – Messeffekte oder Artefakte?
JF  - tm - Technisches Messen . 74 (2007), H. 9
Y1  - 2007
SN  - 0171-8096
SP  - 466
EP  - 476
ER  -