TY  - JOUR
A1  - Pookhalil, Ali
A1  - Amoabediny, Ghassem
A1  - Tabesh, Hadi
A1  - Behbahani, Mehdi
A1  - Mottaghy, Khosrow
T1  - A new approach for semiempirical modeling of mechanical blood trauma
JF  - The international journal of artificial organs
N2  - Purpose
Two semi-empirical models were recently published, both making use of existing literature data, but each taking into account different physical phenomena that trigger hemolysis. In the first model, hemoglobin (Hb) release is described as a permeation procedure across the membrane, assuming a shear stress-dependent process (sublethal model). The second model only accounts for hemoglobin release that is caused by cell membrane breakdown, which occurs when red blood cells (RBC) undergo mechanically induced shearing for a period longer than the threshold time (nonuniform threshold model). In this paper, we introduce a model that considers the hemolysis generated by both these possible phenomena.
Methods
Since hemolysis can possibly be caused by permeation of hemoglobin through the RBC functional membrane as well as by release of hemoglobin from RBC membrane breakdown, our proposed model combines both these models. An experimental setup consisting of a Couette device was utilized for validation of our proposed model.
Results
A comparison is presented between the damage index (DI) predicted by the proposed model vs. the sublethal model vs. the nonthreshold model and experimental datasets. This comparison covers a wide range of shear stress for both human and porcine blood. An appropriate agreement between the measured DI and the DI predicted by the present model was obtained.
Conclusions
The semiempirical hemolysis model introduced in this paper aims for significantly enhanced conformity with experimental data. Two phenomenological outcomes become possible with the proposed approach: an estimation of the average time after which cell membrane breakdown occurs under the applied conditions, and a prediction of the ratio between the phenomena involved in hemolysis.
Y1  - 2016
U6  - https://doi.org/10.5301/ijao.5000474
SN  - 1724-6040
VL  - 39
IS  - 4
SP  - 171
EP  - 177
PB  - Sage
CY  - London
ER  - 
TY  - JOUR
A1  - Müller-Veggian, Mattea
A1  - Haenni, D. R.
A1  - Beuscher, H.
A1  - Bochev, B.
T1  - A new 5.0 ns isomer in ¹⁴⁴ Eu
JF  - Nuclear physics / A. 365 (1981), H. 2
Y1  - 1981
SN  - 0375-9474
SP  - 229
EP  - 236
ER  - 
TY  - JOUR
A1  - Leschinger, Tim
A1  - Birgel, Stefan
A1  - Hackl, Michael
A1  - Staat, Manfred
A1  - Müller, Lars Peter
A1  - Wegmann, Kilian
T1  - A musculoskeletal shoulder simulation of moment arms and joint reaction forces after medialization of the supraspinatus footprint in rotator cuff repair
JF  - Computer Methods in Biomechanics and Biomedical Engineering
Y1  - 2019
U6  - https://doi.org/10.1080/10255842.2019.1572749
IS  - Early view
PB  - Taylor & Francis
CY  - London
ER  - 
TY  - CHAP
A1  - Ermelenko, Y.
A1  - Yoshinobu, T.
A1  - Mourzina, Y.
A1  - Schöning, Michael Josef
A1  - Vlasov, Y.
A1  - Iwasaki, H.
T1  - A multisensor based on laser scanned silicon transducer (LSST): development and properties
T2  - Eurosensors XVII : the 17th European Conference on Solid-State Transducers ; University of Minho, Guimarães, Portugal, September 21 - 24, 2003
Y1  - 2003
SP  - 72
EP  - 73
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Shi, Young de
A1  - Agosti, R.
A1  - Longhini, E.
T1  - A modified casson equation to characterize blood rheology for hypertension. Shi, Young de; Artmann, Gerhard Michael; Agosti, R.; Longhini, E.
JF  - Clinical Hemorheology Microcirculation. 19 (1998), H. 2
Y1  - 1998
SN  - 1386-0291
SP  - 115
EP  - 127
ER  - 
TY  - JOUR
A1  - Näther, Niko
A1  - Auger, V.
A1  - Poghossian, Arshak
A1  - Koudelka-Hep, M.
A1  - Schöning, Michael Josef
T1  - A miniaturized flow-through cell in SU-8 technique for EIS sensors
JF  - Biomedizinische Technik. 49 (2004), H. 2
Y1  - 2004
SN  - 0932-4666
SP  - 994
EP  - 995
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
T1  - A microscopic photometric method for measuring erythrocyte deformability. Artmann, Gerhard Michael
JF  - Clinical Hemorheology. 6 (1986)
Y1  - 1986
SN  - 0271-5198
SP  - 617
EP  - 627
ER  - 
TY  - JOUR
A1  - Moreno i Codinachs, L.
A1  - Birkenstock, C.
A1  - Garma, T.
A1  - Zierold, R.
A1  - Bachmann, J.
A1  - Nielsch, K.
A1  - Schöning, Michael Josef
A1  - Fontcuberta i Morral, A.
T1  - A micron-sized nanoporous multifunction sensing device
JF  - physica status solidi (a) . 206 (2009), H. 3
Y1  - 2009
SN  - 1862-6319
N1  - Special Issue: Engineering of Functional Interfaces (EnFI 08)
SP  - 435
EP  - 441
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Ziemons, Karl
T1  - A measurement of the spin asymmetry of the structure function g1 in deep inelastic muon-proton scattering
JF  - Physics Letters B
N2  - The spin asymmetry in deep inelastic scattering of longitudinally polarised muons by longitudinally polarised protons has been measured over a large x range (0.01<x<0.7). The spin-dependent structure function g1(x) for the proton has been determined and its integral over x found to be 0.114±0.012±0.026, in disagreement with the Ellis-Jaffe sum rule. Assuming the validity of the Bjorken sum rule, this result implies a significant negative value for the integral of g1 for the neutron. These values for the integrals of g1 lead to the conclusion that the total quark spin constitutes a rather small fraction of the spin of the nucleon.
Y1  - 1988
SN  - 0370-2693
N1  - European Muon Collaboration
VL  - 206
IS  - 2
SP  - 364
EP  - 370
ER  - 
TY  - JOUR
A1  - Ziemons, Karl
T1  - A measurement of the ratio of the nucleon structure function in copper and deuterium
JF  - Zeitschrift für Physik C Particles and Fields
N2  - Results are presented on the ratios of the nucleon structure function in copper to deuterium from two separate experiments. The data confirm that the nucleon structure function,F 2, is different for bound nucleons than for the quasi-free ones in the deuteron. The redistribution in the fraction of the nucleon's momentum carried by quarks is investigated and it is found that the data are compatible with no integral loss of quark momenta due to nuclear effects.
Y1  - 1993
SN  - 1431-5858
N1  - European Muon Collaboration
VL  - 57
IS  - 2
SP  - 211
EP  - 218
ER  - 
TY  - JOUR
A1  - Hillen, Walter
T1  - A measurement of &#963;tot(e+e&#8722; &#8594; hadrons) for cm energies between 12.0 and 36.7 GeV. TASSO Collaboration
JF  - Physics Letters B. 113 (1982), H. 6
Y1  - 1982
SP  - 499
EP  - 508
ER  - 
TY  - JOUR
A1  - Grotendorst, Johannes
T1  - A Maple package for transforming series, sequences and functions
JF  - Computer Physics Communications. 67 (1991), H. 2
Y1  - 1991
SN  - 0010-4655
SP  - 325
EP  - 342
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Thust, M.
A1  - Vetter, J.
A1  - Kordos, P. (u.a.)
T1  - A long-term stable penicillin-sensitive potentiometric biosensor with enzyme immobilized by heterobifunctional crosslinking
Y1  - 1996
SN  - 0378-4304
SP  - 115
EP  - 121
ER  - 
TY  - JOUR
A1  - Simonis, A.
A1  - Ruge, C.
A1  - Müller-Veggian, Mattea
A1  - Lüth, H.
A1  - Schöning, Michael Josef
T1  - A long-term stable macroporoustype EIS structure for electrochemical sensor applications
JF  - Sensors and Actuators B. 91 (2003), H. 1-3
Y1  - 2003
SN  - 0925-4005
SP  - 21
EP  - 25
ER  - 
TY  - JOUR
A1  - Wagner, Torsten
A1  - Molina, R.
A1  - Biselli, Manfred
A1  - Canzoneri, Michele
A1  - Schnitzler, Thomas
A1  - Yoshinobu, Tatsuo
A1  - Schöning, Michael Josef
T1  - A light-addressable potentiometric sensor system for fast, simultaneous and spatial detection of the metabolic activity of biological cells
JF  - Transducers '07 Eurosensors XXI : digest of technical papers ; the14th International Conference on Solid-State Sensors, Actuators and Microsystems, June 10-14, 2007, Lyon, France / Gilles Delapierre (Ed.)
Y1  - 2007
SN  - 1-4244-0841-5
N1  - Eurosensors 21, 2007, Lyon ; International Conference on Solid-State Sensors, Actuators and Microsystems 14, 2007, Lyon
SP  - 1107
EP  - 1110
PB  - IEEE
CY  - Piscataway
ER  - 
TY  - JOUR
A1  - Dantism, Shahriar
A1  - Röhlen, Desiree
A1  - Wagner, Torsten
A1  - Wagner, P.
A1  - Schöning, Michael Josef
T1  - A LAPS-based differential sensor for parallelized metabolism monitoring of various bacteria
JF  - Sensors
N2  - Monitoring the cellular metabolism of bacteria in (bio)fermentation processes is crucial to control and steer them, and to prevent undesired disturbances linked to metabolically inactive microorganisms. In this context, cell-based biosensors can play an important role to improve the quality and increase the yield of such processes. This work describes the simultaneous analysis of the metabolic behavior of three different types of bacteria by means of a differential light-addressable potentiometric sensor (LAPS) set-up. The study includes Lactobacillus brevis, Corynebacterium glutamicum, and Escherichia coli, which are often applied in fermentation processes in bioreactors. Differential measurements were carried out to compensate undesirable influences such as sensor signal drift, and pH value variation during the measurements. Furthermore, calibration curves of the cellular metabolism were established as a function of the glucose concentration or cell number variation with all three model microorganisms. In this context, simultaneous (bio)sensing with the multi-organism LAPS-based set-up can open new possibilities for a cost-effective, rapid detection of the extracellular acidification of bacteria on a single sensor chip. It can be applied to evaluate the metabolic response of bacteria populations in a (bio)fermentation process, for instance, in the biogas fermentation process.
Y1  - 2019
U6  - https://doi.org/10.3390/s19214692
SN  - 1424-8220
VL  - 19
IS  - 21
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Nguyen, N.-H.
A1  - Raatschen, Hans-Jürgen
A1  - Staat, Manfred
T1  - A hyperelastic model of biological tissue materials in tubular organs
Y1  - 2010
N1  - ECCM 2010, IV European Conference on Computational Mechanics, Paris, France, May 16-21, 2010.
SP  - 1
EP  - 12
ER  - 
TY  - JOUR
A1  - Gerhards, M.
A1  - Belloum, A.
A1  - Berretz, F.
A1  - Sander, Volker
A1  - Skorupa, S.
T1  - A history-tracing XML-based provenance framework for workflows
Y1  - 2010
SN  - 978-1-4244-8989-3
N1  - Workflows in Support of Large-Scale Science (WORKS), 2010 5th Workshop on
SP  - 1
EP  - 10
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Tsarouchas, D.
A1  - Schaub, A.
A1  - Beckers, L. (u.a.)
T1  - A highly long-term stable silicon-based pH sensor using pulsed laser deposition technique
JF  - Sensors and Actuators B. 35 (1996), H. 1-3
Y1  - 1996
SN  - 0925-4005
SP  - 228
EP  - 233
ER  - 
TY  - JOUR
A1  - Gossmann, Matthias
A1  - Thomas, Ulrich
A1  - Horváth, András
A1  - Dragicevic, Elena
A1  - Stoelzle-Feix, Sonja
A1  - Jung, Alexander
A1  - Raman, Aravind Hariharan
A1  - Staat, Manfred
A1  - Linder, Peter
T1  - A higher-throughput approach to investigate cardiac contractility in vitro under physiological mechanical conditions
JF  - Journal of Pharmacological and Toxicological Methods
Y1  - 2020
U6  - https://doi.org/10.1016/j.vascn.2020.106843
VL  - 105
IS  - Article 106843
PB  - Elsevier
CY  - New York, NY
ER  - 
TY  - JOUR
A1  - Miyamoto, Ko-ichiro
A1  - Hayashi, Kosuke
A1  - Sakamoto, Azuma
A1  - Werner, Frederik
A1  - Wagner, Torsten
A1  - Schöning, Michael Josef
A1  - Yoshinobu, Tatsuo
T1  - A high-Q resonance-mode measurement of EIS capacitive sensor by elimination of series resistance
JF  - Sensor and Actuators B: Chemical
N2  - An EIS capacitive sensor is a semiconductor-based potentiometric sensor, which is sensitive to the ion concentration or pH value of the solution in contact with the sensing surface. To detect a small change in the ion concentration or pH, a small capacitance change must be detected. Recently, a resonance-mode measurement was proposed, in which an inductor was connected to the EIS capacitive sensor and the resonant frequency was correlated with the pH value. In this study, the Q factor of the resonant circuit was enhanced by canceling the internal resistance of the reference electrode and the internal resistance of the inductor coil with the help of a bypass capacitor and a negative impedance converter, respectively. 1% variation of the signal in the developed system corresponded to a pH change of 3.93 mpH, which was about 1/12 of the conventional method, suggesting a better performance in detection of a small pH change.
KW  - Negative impedance convertor
KW  - Resonance-mode measurement
KW  - Chemical sensor
KW  - EIS capacitive sensor
Y1  - 2017
U6  - https://doi.org/10.1016/j.snb.2017.03.002
SN  - 0925-4005
VL  - 248
SP  - 1006
EP  - 1010
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Wagner, Torsten
A1  - Werner, Frederik
A1  - Miyamoto, K.
A1  - Schöning, Michael Josef
A1  - Yoshinobu, T.
T1  - A high-density multi-point LAPS set-up using a VCSEL array and FPGA control
JF  - Procedia Chemistry. 1 (2009), H. 1
Y1  - 2009
SN  - 1876-6196
N1  - Proceedings of the Eurosensors XXIII conference ; Eurosensors 23
SP  - 1483
EP  - 1486
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Wagner, Torsten
A1  - Werner, Frederik
A1  - Miyamoto, Ko-Ichiro
A1  - Schöning, Michael Josef
A1  - Yoshinobu, Tatsuo
T1  - A high-density multi-point LAPS set-up using a VCSEL array and FPGA control
JF  - Sensors and Actuators B: Chemical. 154 (2011), H. 2
Y1  - 2011
SN  - 1873-3077
N1  - EUROSENSORS XXIII
SP  - 124
EP  - 128
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Wagner, Torsten
A1  - Schöning, Michael Josef
A1  - Otto, R.
A1  - Yoshinobu, T.
T1  - A handheld 16 channel pen-type LAPS as a platform for (bio-)electrochemical sensing
JF  - Biomedizinische Technik. 49 (2004), H. 2
Y1  - 2004
SN  - 0932-4666
SP  - 996
EP  - 997
ER  - 
TY  - JOUR
A1  - Baringhaus, Ludwig
A1  - Gaigall, Daniel
T1  - A goodness-of-fit test for the compound Poisson exponential model
JF  - Journal of Multivariate Analysis
N2  - On the basis of bivariate data, assumed to be observations of independent copies of a random vector (S,N), we consider testing the hypothesis that the distribution of (S,N) belongs to the parametric class of distributions that arise with the compound Poisson exponential model. Typically, this model is used in stochastic hydrology, with N as the number of raindays, and S as total rainfall amount during a certain time period, or in actuarial science, with N as the number of losses, and S as total loss expenditure during a certain time period. The compound Poisson exponential model is characterized in the way that a specific transform associated with the distribution of (S,N) satisfies a certain differential equation. Mimicking the function part of this equation by substituting the empirical counterparts of the transform we obtain an expression the weighted integral of the square of which is used as test statistic. We deal with two variants of the latter, one of which being invariant under scale transformations of the S-part by fixed positive constants. Critical values are obtained by using a parametric bootstrap procedure. The asymptotic behavior of the tests is discussed. A simulation study demonstrates the performance of the tests in the finite sample case. The procedure is applied to rainfall data and to an actuarial dataset. A multivariate extension is also discussed.
KW  - Bootstrapping
KW  - Collective risk model
Y1  - 2022
U6  - https://doi.org/10.1016/j.jmva.2022.105154
SN  - 0047-259X
SN  - 1095-7243
VL  - 195
IS  - Article 105154
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Topçu, Murat
A1  - Madabhushi, Gopal S.P.
A1  - Staat, Manfred
T1  - A generalized shear-lag theory for elastic stress transfer between matrix and fibres having a variable radius
JF  - International Journal of Solids and Structures
N2  - A generalized shear-lag theory for fibres with variable radius is developed to analyse elastic fibre/matrix stress transfer. The theory accounts for the reinforcement of biological composites, such as soft tissue and bone tissue, as well as for the reinforcement of technical composite materials, such as fibre-reinforced polymers (FRP). The original shear-lag theory proposed by Cox in 1952 is generalized for fibres with variable radius and with symmetric and asymmetric ends. Analytical solutions are derived for the distribution of axial and interfacial shear stress in cylindrical and elliptical fibres, as well as conical and paraboloidal fibres with asymmetric ends. Additionally, the distribution of axial and interfacial shear stress for conical and paraboloidal fibres with symmetric ends are numerically predicted. The results are compared with solutions from axisymmetric finite element models. A parameter study is performed, to investigate the suitability of alternative fibre geometries for use in FRP.
KW  - Natural fibres
KW  - Polymer-matrix composites
KW  - Biocomposites
KW  - Stress concentrations
KW  - Finite element analysis
Y1  - 2022
U6  - https://doi.org/10.1016/j.ijsolstr.2022.111464
SN  - 0020-7683
VL  - 239–240
IS  - Art. No. 111464
PB  - Elsevier
CY  - New York, NY
ER  - 
TY  - JOUR
A1  - Stulpe, Werner
A1  - Hellwig, K.-E.
T1  - A Formulation of Quantum Stochastic Processes and Some of its Properties. Hellwig, K.-E.; Stulpe, W.
JF  - Foundations of Physics. 13 (1983), H. 7
Y1  - 1983
SN  - 1572-9516
SP  - 673
EP  - 699
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Kloock, Joachim P.
A1  - Mourzina, Y.
A1  - Schubert, J.
T1  - A first step towards a microfabricated thin-film sensor array on the basis of chalcogenide glass materials
JF  - Sensors. 2 (2002), H. 9
Y1  - 2002
SN  - 1424-8220
SP  - 356
EP  - 365
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Krause, R.
A1  - Block, K.
A1  - Musahmeh, M.
A1  - Mulchandani, A.
A1  - Wang, J.
T1  - A dual amperometric/potentiometric FIA-based biosensor for the distinctive detection of organophosphorus pesticides
JF  - Sensors and Actuators B. 95 (2003), H. 1-3
Y1  - 2003
SN  - 0925-4005
SP  - 291
EP  - 296
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Krause, R.
A1  - Block, K.
A1  - Musameh, M.
A1  - Mulchandani, A.
A1  - Wang, J.
T1  - A dual amperometric / potentiometric FIA-based biosensor for the distinctive detection of organophosphorus pesticides
JF  - Book of abstracts / ed. by J. Saneistr.
Y1  - 2002
SN  - 80-01-02576-4
N1  - Eurosensors ; (16, 2002, Praha)
SP  - 76
EP  - 79
PB  - Czech Technical University, Faculty of Electrical Engineering, Department of Measurement
CY  - Prague
ER  - 
TY  - JOUR
A1  - Sander, Volker
A1  - Foster, Ian
A1  - Roy, Alain
A1  - Winkler, Linda
T1  - A differentiated services implementation for high-performance TCP flows
JF  - Computer Networks. 34 (2000), H. 6
Y1  - 2000
SN  - 1389-1286
SP  - 915
EP  - 929
ER  - 
TY  - JOUR
A1  - Bohrn, Ulrich
A1  - Mucha, Andreas
A1  - Werner, Frederik
A1  - Trattner, Barbara
A1  - Bäcker, Matthias
A1  - Krumbe, Christoph
A1  - Schienle, Meinrad
A1  - Stütz, Evamaria
A1  - Schmitt-Landsiedel, Doris
A1  - Fleischer, Maximilian
A1  - Wagner, Patrick
A1  - Schöning, Michael Josef
T1  - A critical comparison of cell-based sensor systems for the detection of Cr (VI) in aquatic environment
JF  - Sensors and actuators. B: Chemical
Y1  - 2013
SN  - 1873-3077 (E-Journal); 0925-4005 (Print)
VL  - Vol. 182
SP  - 58
EP  - 65
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Ditzhaus, Marc
A1  - Gaigall, Daniel
T1  - A consistent goodness-of-fit test for huge dimensional and functional data
JF  - Journal of Nonparametric Statistics
N2  - A nonparametric goodness-of-fit test for random variables with values in a separable Hilbert space is investigated. To verify the null hypothesis that the data come from a specific distribution, an integral type test based on a Cramér-von-Mises statistic is suggested. The convergence in distribution of the test statistic under the null hypothesis is proved and the test's consistency is concluded. Moreover, properties under local alternatives are discussed. Applications are given for data of huge but finite dimension and for functional data in infinite dimensional spaces. A general approach enables the treatment of incomplete data. In simulation studies the test competes with alternative proposals.
KW  - Cramér-von-Mises statistic
KW  - separable Hilbert space
KW  - huge dimensional data
KW  - functional data
Y1  - 2018
U6  - https://doi.org/10.1080/10485252.2018.1486402
SN  - 1029-0311
VL  - 30
IS  - 4
SP  - 834
EP  - 859
PB  - Taylor & Francis
CY  - Abingdon
ER  - 
TY  - JOUR
A1  - Digel, Ilya
A1  - Dachwald, Bernd
A1  - Artmann, Gerhard
A1  - Linder, Peter
A1  - Funke, O.
T1  - A concept of a probe for particle analysis and life detection in icy environments
Y1  - 2009
N1  - International workshop “Europa lander: science goals and experiments”, Space Research Institute (IKI), Moscow, Russia
9-13 February 2009
SP  - 1
EP  - 24
ER  - 
TY  - JOUR
A1  - Bhattarai, Aroj
A1  - Staat, Manfred
T1  - A computational study of organ relocation after laparoscopic pectopexy to repair posthysterectomy vaginal vault prolapse
JF  - Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization
Y1  - 2019
U6  - https://doi.org/10.1080/21681163.2019.1670095
SN  - 2168-1171
PB  - Taylor & Francis
CY  - London
ER  - 
TY  - JOUR
A1  - Streun, M.
A1  - Larue, H.
A1  - Parl, C.
A1  - Ziemons, Karl
T1  - A compact PET detector readout using charge-to-time conversion
JF  - 2009 IEEE Nuclear Science Symposium Conference Record (NSS/MIC)
N2  - The readout of gamma detectors is considerably simplified when the event intensity is encoded as a pulse width (Pulse Width Modulation, PWM). Time-to-Digital-Converters (TDC) replace the conventional ADCs and multiple TDCs can be realized easily in one PLD chip (Programmable Logic Device). The output of a PWM stage is only one digital signal per channel which is well suited for transport so that further processing can be performed apart from the detector. This is particularly interesting for large systems with high channel density (e.g. high resolution scanners). In this work we present a circuit with a linear transfer function that requires a minimum of components by performing the PWM already in the preamp stage. This allows a very compact and also cost-efficient implementation of the front-end electronics.
Y1  - 2009
SN  - 1082-3654
SP  - 1868
EP  - 1870
PB  - IEEE
CY  - New York
ER  - 
TY  - JOUR
A1  - Stulpe, Werner
A1  - Hellwig, K.-E.
T1  - A Classical Reformulation of Finite-Dimensional Quantum Mechanics. Hellwig, K.-E.; Stulpe, W.
JF  - Quantum measurement, irreversibility and the physics of information / Symposium on the Foundations of Modern Physics 1993, Cologne, Germany 1 - 5 June 1993. Ed. Paul Busch
Y1  - 1993
SN  - 981021507X
N1  - Symposium on the Foundations of Modern Physics ; <1993, Köln>
SP  - 209
EP  - 214
PB  - World Scientific
CY  - Singapore [u.a.]
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Arzdorf, M.
A1  - Mulchandani, P.
A1  - Chen, W.
A1  - Mulchandani, A.
T1  - A capacitive field-effect sensor for the direct determination of organophosphorus pesticides
JF  - Sensors and Actuators B. 91 (2003), H. 1-3
Y1  - 2003
SN  - 0925-4005
SP  - 92
EP  - 97
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Crott, M.
A1  - Ronkel, F.
A1  - Thust, M.
A1  - Schultze, J. W.
A1  - Kordos, P.
A1  - Lüth, H.
T1  - A capacitive chemical sensor based on porous silicon
JF  - Proceedings of the 26th European Solid State Device Research Conference : Congress Centre, Bologna, Italy, 9 - 11 September 1996 / ESSDERC '96. Ed. by G. Baccarani
Y1  - 1996
SN  - 2-86332-196-X
N1  - ESSDERC ; (26, 1996, Bologna) ; European Solid State Device Research Conference (ESSDERC)
SP  - 907
EP  - 910
PB  - Ed. Frontières
CY  - Gif-sur-Yvette
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Schütz, S.
A1  - Schroth, P.
A1  - Weißbecker, B.
A1  - Steffen, A.
A1  - Kordos, P.
A1  - Hummel, Hans E.
T1  - A BioFET on the basis of intact insect antennae
JF  - Sensors and Actuators B. 47 (1998), H. 1-3
Y1  - 1998
SN  - 0925-4005
SP  - 235
EP  - 238
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Schütz, S.
A1  - Riemer, A.
A1  - Weißbecker, B.
A1  - Steffen, A.
A1  - Kordos, P.
A1  - Lüth, H.
A1  - Hummel, Hans E.
T1  - A BioFET on the basis of intact insect antennae
JF  - Proceedings of the 11th European Conference on Solid-State Transducers / Eurosensors XI, September 21 - 24, 1997, Warsaw, Poland. [Organised by] Warsaw University of Technology. Vol 2.
Y1  - 1997
SN  - 83-908335-0-6
N1  - Eurosensors ; (11, 1997, Warszawa) ; Eurosensors - European Conference on Solid-State Transducers ; (11 : ; 1997.09.21-24 : ; Warsaw)
SP  - 1461
EP  - 1464
PB  - Sensor Lab Sp.
CY  - Warsaw
ER  - 
TY  - BOOK
A1  - Laack, Walter van
T1  - A better history of our world / Vol. 3. Death
Y1  - 2003
SN  - 978-3-936624-01-4
N1  - [Eine bessere Geschichte unserer Welt <engl.>]
PB  - van Laack
CY  - Aachen
ER  - 
TY  - BOOK
A1  - Laack, Walter van
T1  - A better history of our world / Vol. 2. Life
Y1  - 2002
SN  - 978-3-8311-2597-5
N1  - [Eine bessere Geschichte unserer Welt <engl.>]
PB  - van Laack
CY  - Aachen
ER  - 
TY  - BOOK
A1  - Laack, Walter van
T1  - A better history of our world / Vol. 1. The universe
Y1  - 2001
SN  - 978-3-8311-1490-0
N1  - [Eine bessere Geschichte unserer Welt <engl.>]
PB  - van Laack
CY  - Aachen
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Simonis, Anette
A1  - Ruge, Christian
A1  - Ecken, Holger
A1  - Müller-Veggian, Mattea
A1  - Lüth, Hans
T1  - A (bio-)chemical Field-effect Sensor with Macroporous Si as Substrate Material and a SiO₂ / LPCVD-Si₃N₄ Double Layer as pH Transducer
JF  - Sensors. 2 (2002), H. 1
N2  - Macroporous silicon has been etched from n-type Si, using a vertical etching cell where no rear side contact on the silicon wafer is necessary. The resulting macropores have been characterised by means of Scanning Electron Microscopy (SEM). After etching, SiO₂ was thermally grown on the top of the porous silicon as an insulating layer and Si₃N₄ was deposited by means of Low Pressure Chemical Vapour Deposition (LPCVD) as transducer material to fabricate a capacitive pH sensor. In order to prepare porous biosensors, the enzyme penicillinase has been additionally immobilised inside the porous structure. Electrochemical measurements of the pH sensor and the biosensor with an Electrolyte/Insulator/Semiconductor (EIS) structure have been performed in the Capacitance/Voltage (C/V) and Constant capacitance (ConCap) mode.
Y1  - 2002
SN  - 1424-8220
U6  - https://doi.org/10.3390/s20100011
SP  - 11
EP  - 22
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Mogilevskiĭ, A. Ia.
A1  - Shilo, A. V.
A1  - Panchekha, A. P.
T1  - [Chaotic non-linear dynamics of alpha-band of the EEg and organization of the cortical activity of P300 wave] / Mogilevskiĭ, A. Ia. ; Kotliar, K. E. ; Shilo, A. V. ; Panchekha, A. P.
JF  - Zhurnal vyssheĭ nervnoĭ deiatelnosti imeni I P Pavlova. 58 (2008), H. 5
Y1  - 2008
SN  - 0044-4677
N1  - Original in Russisch ; English abstract
SP  - 562
EP  - 575
PB  - -
ER  - 
TY  - JOUR
A1  - Müller-Veggian, Mattea
A1  - Garbe, S.
A1  - Nour, Y.
A1  - Wolf, K.
T1  - 468 Scatter dose determination at the eye lens during a mask based whole brain radiotherapy (WBRT)
JF  - Radiotherapy and Oncology
Y1  - 2005
U6  - https://doi.org/10.1016/S0167-8140(05)81444-6
SN  - 0167-8140
VL  - 76
IS  - Suppl. 2
SP  - S202
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Jansen, Sebastian
A1  - Behbahani, Mehdi
A1  - Laumen, Marco
A1  - Kaufmann, Tim
A1  - Hormes, Marcus
A1  - Schmitz-Rode, Thomas
A1  - Behr, Marek
A1  - Steinseifer, Ulrich
T1  - 3D Stereo-PIV Validation for CFD-Simulation of Steady Flow through the Human Aorta using Rapid-Prototyping techniques
Y1  - 2010
N1  - abstract ; IV International Symposium on Modelling of Physiological Flows, Sardinia, Italy, June 02-05, 2010 ; MPF2010
ER  - 
TY  - JOUR
A1  - Achtsnicht, Stefan
A1  - Tödter, Julia
A1  - Niehues, Julia
A1  - Telöken, Matthias
A1  - Offenhäusser, Andreas
A1  - Krause, Hans-Joachim
A1  - Schröper, Florian
T1  - 3D printed modular immunofiltration columns for frequency mixing-based multiplex magnetic immunodetection
JF  - Sensors
N2  - For performing point-of-care molecular diagnostics, magnetic immunoassays constitute a promising alternative to established enzyme-linked immunosorbent assays (ELISA) because they are fast, robust and sensitive. Simultaneous detection of multiple biomolecular targets from one body fluid sample is desired. The aim of this work is to show that multiplex magnetic immunodetection based on magnetic frequency mixing by means of modular immunofiltration columns prepared for different targets is feasible. By calculations of the magnetic response signal, the required spacing between the modules was determined. Immunofiltration columns were manufactured by 3D printing and antibody immobilization was performed in a batch approach. It was shown experimentally that two different target molecules in a sample solution could be individually detected in a single assaying step with magnetic measurements of the corresponding immobilization filters. The arrangement order of the filters and of a negative control did not influence the results. Thus, a simple and reliable approach to multi-target magnetic immunodetection was demonstrated.
Y1  - 2019
U6  - https://doi.org/10.3390/s19010148
SN  - 1424-8220
VL  - 19
IS  - 1
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Hillen, Walter
A1  - Fischer, Felix
A1  - Paulus, Dietrich
T1  - 3D Presentation States: Parametrisierung und Speicherung der 3D-Darstellung von segmentierten medizinischen Volumendaten / Fischer, Felix ; Hillen, Walter ; Paulus, Dietrich
JF  - Biomedizinische Technik. 52 (2007), H. Ergänzungsband
Y1  - 2007
SN  - 0939-4990
N1  - BMT 2007, 41. Jahrestagung der DGBMT - Deutschen Gesellschaft für Biomedizinische Technik im VDE, Aachen, DE, 26.-29. Sep, 2007
SP  - 1
EP  - 2
ER  - 
TY  - JOUR
A1  - Kaminsky, Radoslav
A1  - Kallweit, Stephan
A1  - Weber, Hans-Joachim
A1  - Simons, Antoine
A1  - Kramm, K.
A1  - Jazwik, K.
A1  - Moll, J.
A1  - Verdonck, P.
T1  - 3D high speed piv assessment of a new aortic heart valve prototype
JF  - Journal of biomechanics. 39 (2006), H. Supplement 1
Y1  - 2006
SN  - 0021-9290
N1  - World Congress of Biomechanics <5, 2006, München>: Abstracts of the 5th World Congress of Biomechanics
SP  - S304
EP  - S305
PB  - -
ER  - 
TY  - JOUR
A1  - Langen, Karl J.
A1  - Ziemons, Karl
A1  - Kiwit, Jürgen C. W.
A1  - Herzog, Hans
A1  - Kuwert, Torsten
A1  - Bock, Wolfgang
A1  - Stöcklin, Gerhard
A1  - Feinendegen, Ludwig E.
A1  - Müller-Gärtner, Hans-W.
T1  - 3-[123I]iodo-α-methyltyrosine and [methyl-11C]-L-methionine uptake in cerebral gliomas: a compara-tive study using SPECT and PET
JF  - Journal of Nuclear Medicine
Y1  - 1997
SN  - 0161-5505
VL  - 38
IS  - 4
SP  - 517
EP  - 522
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
T1  - 2nd International Conference on Medical Biorheology (ICMB). Shanghai, China, September 13-15, 1995. Shi, Young de, Artmann, Gerhard Michael, Meiselman, Herbert J.
JF  - Biorheology. 33 (1996), H. 6
Y1  - 1996
SN  - 0006-355x
SP  - 505
EP  - 507
ER  - 
TY  - JOUR
A1  - Müller-Veggian, Mattea
A1  - Beuscher, H.
A1  - Lieder, R. M.
T1  - 10+ isomers observed in even-even 78-neutron nuclei
JF  - Zeitschrift für Physik / A, Hadrons and nuclei. 290 (1979), H. 1
Y1  - 1979
SN  - 0340-2193
N1  - 2. ISSN: 0930-1151 ; 3. ISSN: 0939-7922
SP  - 43
EP  - 46
ER  - 
TY  - JOUR
A1  - Muschallik, Lukas
A1  - Molinnus, Denise
A1  - Bongaerts, Johannes
A1  - Pohl, Martina
A1  - Wagner, Torsten
A1  - Schöning, Michael Josef
A1  - Siegert, Petra
A1  - Selmer, Thorsten
T1  - (R,R)-Butane-2,3-diol Dehydrogenase from Bacillus clausii DSM 8716T: Cloning and Expression of the bdhA-Gene, and Initial Characterization of Enzyme
JF  - Journal of Biotechnology
N2  - The gene encoding a putative (R,R)-butane-2,3-diol dehydrogenase (bdhA) from Bacillus clausii DSM 8716T was isolated, sequenced and expressed in Escherichia coli. The amino acid sequence of the encoded protein is only distantly related to previously studied enzymes (identity 33–43%) and exhibited some uncharted peculiarities. An N-terminally StrepII-tagged enzyme variant was purified and initially characterized. The isolated enzyme catalyzed the (R)-specific oxidation of (R,R)- and meso-butane-2,3-diol to (R)- and (S)-acetoin with specific activities of 12 U/mg and 23 U/mg, respectively. Likewise, racemic acetoin was reduced with a specific activity of up to 115 U/mg yielding a mixture of (R,R)- and meso-butane-2,3-diol, while the enzyme reduced butane-2,3-dione (Vmax 74 U/mg) solely to (R,R)-butane-2,3-diol via (R)-acetoin. For these reactions only activity with the co-substrates NADH/NAD+ was observed. The enzyme accepted a selection of vicinal diketones, α-hydroxy ketones and vicinal diols as alternative substrates. Although the physiological function of the enzyme in B. clausii remains elusive, the data presented herein clearly demonstrates that the encoded enzyme is a genuine (R,R)-butane-2,3-diol dehydrogenase with potential for applications in biocatalysis and sensor development.
Y1  - 2017
U6  - https://doi.org/10.1016/j.jbiotec.2017.07.020
SN  - 0168-1656
VL  - 258
SP  - 41
EP  - 50
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - CHAP
A1  - Poghossian, Arshak
A1  - Abouzar, Maryam H.
A1  - Schöning, Michael Josef
ED  - Abdelghani, Adnane
ED  - Schöning, Michael Josef
T1  - (Bio-­)chemical sensor array based on nanoplate SOI capacitors
T2  - Nanoscale Science and Technology (NS&T´12) : Proceedings Book Humboldt Kolleg ; Tunisia, 17-19 March, 2012
Y1  - 2012
SP  - 31
EP  - 31
ER  - 
TY  - CHAP
A1  - Yoshinobu, Tatsuo
A1  - Krause, Steffi
A1  - Miyamoto, Ko-ichiro
A1  - Werner, Frederik
A1  - Poghossian, Arshak
A1  - Wagner, Torsten
A1  - Schöning, Michael Josef
T1  - (Bio-)chemical Sensing and Imaging by LAPS and SPIM
T2  - Label-free biosensing: advanced materials, devices and applications
N2  - The light-addressable potentiometric sensor (LAPS) and scanning photo-induced impedance microscopy (SPIM) are two closely related methods to visualise the distributions of chemical species and impedance, respectively, at the interface between the sensing surface and the sample solution. They both have the same field-effect structure based on a semiconductor, which allows spatially resolved and label-free measurement of chemical species and impedance in the form of a photocurrent signal generated by a scanning light beam. In this article, the principles and various operation modes of LAPS and SPIM, functionalisation of the sensing surface for measuring various species, LAPS-based chemical imaging and high-resolution sensors based on silicon-on-sapphire substrates are described and discussed, focusing on their technical details and prospective applications.
KW  - Chemical imaging
KW  - Field-effect device
KW  - Light-addressable potentiometric sensor
KW  - Potentiometry
Y1  - 2018
SN  - 978-3-319-75219-8
SP  - 103
EP  - 132
PB  - Springer
CY  - Cham
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Lüth, H.
A1  - Schultze, J. W.
A1  - Schöning, Michael Josef
T1  - (Bio-)chemical and physical microsensor array using an identical transducer principle
JF  - Scaling down in electrochemistry : electrochemical micro- and nanosystem technology ; proceedings of the 3rd International Symposium on Electrochemical Microsystem Technologies, Garmisch-Patenkirchen, Germany, 11 - 15 September 2000 / ed. by J. W. Schultz
Y1  - 2001
SN  - 0-08-044014-2
SP  - 243
EP  - 249
PB  - Elsevier [u.a.]
CY  - Amsterdam [u.a.]
ER  - 
TY  - JOUR
A1  - Buniatyan, V. V.
A1  - Matirosyan, N. W.
A1  - Abouzar, Maryam H.
A1  - Schöning, Michael Josef
A1  - Poghossian, Arshak
A1  - Schubert, J.
A1  - Khachatryan, V. R.
A1  - Soukiassyan, G. R.
T1  - (Ba,Sr)TiO3 based electrolyte-insulator-semiconductor pHsensors: comparitive study
JF  - Semiconductor micro- and nanoelectronics : Proceedings of the Seventh International Conference , Tsakhcadzor, Armenia July 3-5 2009
Y1  - 2009
SP  - 71
EP  - 74
ER  - 
TY  - JOUR
A1  - Hillen, Walter
T1  - &#960;0 production by e+e&#8722; annihilation at 14 and 34 GeV c.m. energy . TASSO Collaboration
JF  - Physics Letters B. 108 (1982), H. 1
Y1  - 1982
SN  - 0370-2693
SP  - 71
EP  - 76
ER  - 
TY  - JOUR
A1  - Hillen, Walter
T1  - &#923;, Image  production in e+e- annihilation at 33 GeV centre of mass energy. TASSO Collaboration
JF  - Physics Letters B. 105 (1981), H. 4
Y1  - 1981
SN  - 0370-2693
SP  - 75
EP  - 80
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
T1  - "Voltohmmetry" – a new transducer principle for electrochemical sensors
JF  - Ultrathin electrochemical chemo- and biosensors : technology and performance / Vladimir M. Mirsky
Y1  - 2004
SN  - 3-540-21285-X
SP  - 117
EP  - 140
PB  - Springer
CY  - Berlin [u.a.]
ER  - 
TY  - JOUR
A1  - Müller-Veggian, Mattea
A1  - Kreiner, A. J.
A1  - Fenzl, M.
A1  - Kutschera, W.
T1  - "Semientkoppelte" Rotationsstrukturen in ¹⁹⁴,¹⁹⁶ Tl
JF  - Frühjahrstagung ... des Fachausschusses Kernphysik und Hochenergiephysik der DPG (Sektion A: Kernphysik) / Deutsche Physikalische Gesellschaft (1978)
Y1  - 1978
SP  - 773
PB  - Physik-Verlag
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
T1  - "Playing around“ with field-effect sensors on the basis of EIS structures, LAPS and ISFETs
JF  - Sensors. 5 (2005), H. 3
Y1  - 2005
SN  - 1424-8220
SP  - 126
EP  - 138
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
T1  - "High-order” hybrid FET module for (bio)chemical and physical sensing
JF  - Integrated analytical systems / ed. by Salvador Alegret
Y1  - 2003
SN  - 0-444-51037-0
SP  - 587
EP  - 623
PB  - Elsevier
CY  - Amsterdam [u.a.]
ER  -