TY - JOUR
A1 - Grüters, Hugo
A1 - Savvidis, E.
A1 - Löer, F.
A1 - Wiesener, C. H.
T1 - Analyse der Beanspruchung des proximalen Femur bei verschiedenen Arten der Belastung mit Hilfe der Finite-Element-Methode / Savvidis, E. ; Löer, F. ; Grüters, Hugo ; Wiesener, C. H.
JF - Zeitschrift für Orthopädie und ihre Grenzgebiete. 129 (1991), H. 3
Y1 - 1991
SN - 1615-9586
SP - 268
EP - 277
ER -
TY - JOUR
A1 - Grüters, Hugo
A1 - Senger, W.
T1 - Simulation des biomechanisch durch Energiedehnung stimulierten Knochenumbaus
JF - Biomedizinische Technik. 57 (1992), H. Ergänzungsband 1
Y1 - 1992
SN - 0013-5585
SP - 39
EP - 41
ER -
TY - JOUR
A1 - Gun, Jenny
A1 - Gutkin, Vitaly
A1 - Lev, Ovadia
A1 - Boyen, Hans-Gerd
A1 - Saitner, Marc
A1 - Wagner, Patrick
A1 - Olieslaeger, Marc D´
A1 - Abouzar, Maryam H.
A1 - Poghossian, Arshak
A1 - Schöning, Michael Josef
T1 - Tracing gold nanoparticle charge by electrolyte-insulator-semiconductor devices
JF - Journal of Physical Chemistry C. 115 (2011), H. 11
Y1 - 2011
SN - 1932-7455
SP - 4439
EP - 4445
PB - American Cemical Society
CY - Washington, DC
ER -
TY - JOUR
A1 - Gun, Jenny
A1 - Rizkov, Dan
A1 - Lev, Ovadia
A1 - Abouzar, Maryam H.
A1 - Poghossian, Arshak
A1 - Schöning, Michael Josef
T1 - Oxygen plasma-treated gold nanoparticle-based field-effect devices as transducer structures for bio-chemical sensing
JF - Microchimica Acta. 164 (2008), H. 3-4
Y1 - 2008
SN - 1436-5073
SP - 395
EP - 404
ER -
TY - JOUR
A1 - Gun, Jenny
A1 - Schöning, Michael Josef
A1 - Abouzar, Maryam H.
A1 - Poghossian, Arshak
A1 - Katz, Evgeny
T1 - Field-Effect Nanoparticle-Based Glucose Sensor on a Chip: Amplification Effect of Coimmobilized Redox Species
JF - Electroanalysis. 20 (2008), H. 16
Y1 - 2008
SN - 1521-4109
SP - 1748
EP - 1753
ER -
TY - JOUR
A1 - Guo, Yuanyuan
A1 - Miyamoto, Ko-ichiro
A1 - Wagner, Torsten
A1 - Schöning, Michael Josef
A1 - Yoshinobu, Tatsuo
T1 - Device simulation of the light-addressable potentiometric sensor for the investigation of the spatial resolution
JF - Sensors and actuators B: Chemical
N2 - As a semiconductor-based electrochemical sensor, the light-addressable potentiometric sensor (LAPS) can realize two dimensional visualization of (bio-)chemical reactions at the sensor surface addressed by localized illumination. Thanks to this imaging capability, various applications in biochemical and biomedical fields are expected, for which the spatial resolution is critically significant. In this study, therefore, the spatial resolution of the LAPS was investigated in detail based on the device simulation. By calculating the spatiotemporal change of the distributions of electrons and holes inside the semiconductor layer in response to a modulated illumination, the photocurrent response as well as the spatial resolution was obtained as a function of various parameters such as the thickness of the Si substrate, the doping concentration, the wavelength and the intensity of illumination.
The simulation results verified that both thinning the semiconductor substrate and increasing the doping concentration could improve the spatial resolution, which were in good agreement with known experimental results and theoretical analysis. More importantly, new findings of interests were also obtained. As for the dependence on the wavelength of illumination, it was found that the known dependence was not always the case. When the Si substrate was thick, a longer wavelength resulted in a higher spatial resolution which was known by experiments. When the Si substrate was thin, however, a longer wavelength of light resulted in a lower spatial resolution. This finding was explained as an effect of raised concentration of carriers, which reduced the thickness of the space charge region.
The device simulation was found to be helpful to understand the relationship between the spatial resolution and device parameters, to understand the physics behind it, and to optimize the device structure and measurement conditions for realizing higher performance of chemical imaging systems.
Y1 - 2014
U6 - https://doi.org/10.1016/j.snb.2014.08.016
SN - 1873-3077 (E-Journal); 0925-4005 (Print)
VL - 204
SP - 659
EP - 665
PB - Elsevier
CY - Amsterdam
ER -
TY - JOUR
A1 - Guo, Yuanyuan
A1 - Seki, Kosuke
A1 - Miyamoto, Ko-ichiro
A1 - Wagner, Torsten
A1 - Schöning, Michael Josef
A1 - Yoshinobu, Tatsuo
T1 - Novel photoexcitation method for light-addressable potentiometric sensor with higher spatial resolution
JF - Applied physics express : APEX
N2 - A novel photoexcitation method for the light-addressable potentiometric sensor (LAPS) is proposed to achieve a higher spatial resolution of chemical images. The proposed method employs a combined light source that consists of a modulated light probe, which generates the alternating photocurrent signal, and a ring of constant illumination surrounding it. The constant illumination generates a sheath of carriers with increased concentration which suppresses the spread of photocarriers by enhanced recombination. A device simulation was carried out to verify the effect of constant illumination on the spatial resolution, which demonstrated that a higher spatial resolution can be obtained.
Y1 - 2014
U6 - https://doi.org/10.7567/APEX.7.067301
SN - 1882-0786 (E-Journa); 1882-0778 (Print)
VL - 7
IS - 6
SP - 067301-4
PB - IOP
CY - Bristol
ER -
TY - JOUR
A1 - Guo, Yuanyuan
A1 - Seki, Kosuke
A1 - Miyamoto, Ko-ichiro
A1 - Wagner, Torsten
A1 - Schöning, Michael Josef
A1 - Yoshinobu, Tatsuo
T1 - Device simulation of the light-addressable potentiometric sensor with a novel photoexcitation method for a higher spatial resolution
JF - Procedia Engineering
N2 - A novel photoexcitation method for the light-addressable potentiometric sensor (LAPS) realized a higher spatial resolution of chemical imaging. In this method, a modulated light probe, which generates the alternating photocurrent signal, is surrounded by a ring of constant light, which suppresses the lateral diffusion of photocarriers by enhancing recombination. A device simulation verified that a higher spatial resolution could be obtained by adjusting the gap between the modulated and constant light. It was also found that a higher intensity and a longer wavelength of constant light was more effective. However, there exists a tradeoff between the spatial resolution and the amplitude of the photocurrent, and thus, the signal-to-noise ratio. A tilted incidence of constant light was applied, which could achieve even higher resolution with a smaller loss of photocurrent.
KW - Light-addressable Potentiometric Sensor
KW - novel photoexcitation method
KW - tilted constant illumination
KW - spatial resolution
Y1 - 2014
U6 - https://doi.org/10.1016/j.proeng.2014.11.369
SN - 1877-7058
N1 - EUROSENSORS 2014 ; European Conference on Solid-State Transducers <28, 2014>
VL - 87
SP - 456
EP - 459
PB - Elsevier
CY - Amsterdam
ER -
TY - JOUR
A1 - Gutheil, Inge
A1 - Berg, Tommy
A1 - Grotendorst, Johannes
T1 - Performance Analysis of Parallel Eigensolvers of two Libraries on BlueGene/P
JF - Journal of Mathematics and Systems Science
N2 - Many applications in computational science and engineering require the computation of eigenvalues and vectors of dense symmetric or Hermitian matrices. For example, in DFT (density functional theory) calculations on modern supercomputers 10% to 30% of the eigenvalues and eigenvectors of huge dense matrices have to be calculated. Therefore, performance and parallel scaling of the used eigensolvers is of upmost interest. In this article different routines of the linear algebra packages ScaLAPACK and Elemental for parallel solution of the symmetric eigenvalue problem are compared concerning their performance on the BlueGene/P supercomputer. Parameters for performance optimization are adjusted for the different data distribution methods used in the two libraries. It is found that for all test cases the new library Elemental which uses a two-dimensional element by element distribution of the matrices to the processors shows better performance than the old ScaLAPACK library which uses a block-cyclic distribution.
KW - performance analysis
KW - Elemental
KW - ScaLAPACK
KW - eigensolvers
KW - Numerical linear algebra
Y1 - 2012
U6 - https://doi.org/10.17265/2159-5291/2012.04.003
SN - 2159-5291
VL - 2
IS - 4
SP - 231
EP - 236
PB - David Publishing
CY - Libertyville
ER -
TY - JOUR
A1 - Göddeke, Dominik
A1 - Strzodka, Robert
A1 - Mohd-Yusof, Jamaludin
A1 - McCormick, Patrick
A1 - Buijssen, Sven H.M.
A1 - Grajewski, Matthias
A1 - Turek, Stefan
T1 - Exploring weak scalability for FEM calculations on a GPU-enhanced cluster
JF - Parallel Computing
Y1 - 2007
U6 - https://doi.org/10.1016/j.parco.2007.09.002
SN - 0167-8191
VL - 33
IS - 10-11
SP - 685
EP - 699
ER -
TY - JOUR
A1 - Hacker, Tobias
A1 - Kraft, Bodo
A1 - Zöll, Axel
T1 - Projektzuschnitt für die inkrementelle Systementwicklung im Konzernverbund
Y1 - 2011
SN - 978-3-8322-9990-3
N1 - Zusammenspiel von Vorgehensmodellen und Organisationsformen, Workshop der Fachgruppe WI-VM der Gesellschaft für Informatik, 18
SP - 78
EP - 83
ER -
TY - JOUR
A1 - Hackl, M.
A1 - Andermahr, J.
A1 - Staat, Manfred
A1 - Bremer, I.
A1 - Borggrefe, J.
A1 - Prescher, A.
A1 - Müller, L. P.
A1 - Wegmann, K.
T1 - Suture button reconstruction of the central band of the interosseous membrane in Essex-Lopresti lesions: a comparative biomechanical investigation
JF - The Journal of Hand Surgery (European Volume)
Y1 - 2017
U6 - https://doi.org/10.1177/1753193416665943
SN - 2043-6289 (Online)
SN - 1753-1934 (Print)
VL - 42
IS - 4
SP - 370
EP - 376
PB - Sage
CY - London
ER -
TY - JOUR
A1 - Hackl, Michael
A1 - Kahmann, Stephanie Lucina
A1 - Wegmann, Kilian
A1 - Ries, Christian
A1 - Staat, Manfred
A1 - Müller, Lars-Peter
T1 - Shortening osteotomy of the proximal radius — a treatment option for isolated osteoarthritis of the lateral column of the elbow joint?
JF - Knee surgery, sports traumatology, arthroscopy
N2 - Treatment of posttraumatic osteoarthritis of the radial column of the elbow joint remains a challenging yet common issue.
While partial joint replacement leads to high revision rates, radial head excision has shown to severely increase joint instability. Shortening osteotomy of the radius could be an option to decrease the contact pressure of the radiohumeral joint and thereby pain levels without causing valgus instability. Hence, the aim of this biomechanical study was to evaluate the effects of radial shortening on axial load distribution and valgus stability of the elbow joint.
Y1 - 2016
U6 - https://doi.org/10.1007/s00167-016-4080-7
SN - 0942-2056
VL - Volume 24
IS - Supplement 1
SP - 128
EP - 129
PB - Springer
CY - Berlin
ER -
TY - JOUR
A1 - Hackl, Michael
A1 - Leschinger, T.
A1 - Staat, Manfred
A1 - Müller, Lars-Peter
A1 - Wegmann, Kilian
T1 - Reconstruction of the interosseous membrane in the Essex Lopresti lesion — a biomechanical evaluation
JF - Knee surgery, sports traumatology, arthroscopy
N2 - Surgical reconstruction of the interosseous membrane (IOM) could restore longitudinal forearm stability to avoid persisting disability due to capituloradial and ulnocarpal impingement in Essex Lopresti lesions. This biomechanical study aimed to assess longitudinal forearm stability of intact specimens, after sectioning of the IOM and after reconstruction with a TightRope construct using either a single or double bundle technique.
Y1 - 2016
U6 - https://doi.org/10.1007/s00167-016-4080-7
SN - 0942-2056
VL - Volume 24
IS - Supplement 1
SP - 130
EP - 131
PB - Springer
CY - Berlin
ER -
TY - JOUR
A1 - Hackl, Michael
A1 - Müller, Lars-Peter
A1 - Staat, Manfred
A1 - Kahmann, Stephanie Lucina
A1 - Wegmann, Kilian
T1 - Proximal phalangeal neck fractures of the hand — a biomechanical comparison of three fixation techniques
JF - Knee surgery, sports traumatology, arthroscopy
N2 - Plate osteosynthesis of displaced proximal phalangeal neck fractures of the hand allows early mobilization due to a stable internal fixation. Nevertheless, joint stiffness—because of soft tissue irritation—represents a common complication leading to high complication rates. Del Pinal et al. recently reported promising clinical results for a new, minimally invasive fixation technique with a cannulated headless intramedullary compression screw. Hence, the aim of this study was to compare plate fixation of proximal phalangeal neck fractures to less two less invasive techniques: Crossed k-wire fixation and intramedullary screw fixation. We hypothesized that these fixation techniques provide inferior stability when compared to plate osteosynthesis.
Y1 - 2016
U6 - https://doi.org/10.1007/s00167-016-4080-7
SN - 0942-2056
VL - Volume 24
IS - Supplement 1
SP - 148
EP - 149
PB - Springer
CY - Berlin
ER -
TY - JOUR
A1 - Hackl, Michael
A1 - Nacov, Julia
A1 - Kammerlohr, Sandra
A1 - Staat, Manfred
A1 - Buess, Eduard
A1 - Leschinger, Tim
A1 - Müller, Lars P.
A1 - Wegmann, Kilian
T1 - Intratendinous Strain Variations of the Supraspinatus Tendon Depending on Repair Technique: A Biomechanical Analysis Regarding the Cause of Medial Cuff Failure
JF - The American Journal of Sports Medicine
Y1 - 2021
U6 - https://doi.org/10.1177/03635465211006138
SN - 1552-3365
SN - 0363-5465
VL - 49
IS - 7
SP - 1847
EP - 1853
PB - Sage
CY - London
ER -
TY - JOUR
A1 - Hackl, Michael
A1 - Wegmann, Kilian
A1 - Kahmann, Stephanie Lucina
A1 - Heinze, Nicolai
A1 - Staat, Manfred
A1 - Neiss, Wolfram F.
A1 - Scaal, Martin
A1 - Müller, Lars P.
T1 - Radial shortening osteotomy reduces radiocapitellar contact pressures while preserving valgus stability of the elbow
JF - Knee Surgery, Sports Traumatology, Arthroscopy
Y1 - 2017
U6 - https://doi.org/10.1007/s00167-017-4468-z
SN - 1433-7347
VL - 25
IS - 7
SP - 2280
EP - 2288
PB - Springer
CY - Berlin
ER -
TY - JOUR
A1 - Hafner, David
A1 - Demetz, Oliver
A1 - Weickert, Joachim
A1 - Reißel, Martin
T1 - Mathematical Foundations and Generalisations of the Census Transform for Robust Optic Flow Computation
JF - Journal of Mathematical Imaging and Vision
Y1 - 2014
U6 - https://doi.org/10.1007/s10851-014-0529-9
SN - 1573-7683 (Online)
N1 - Springer Online First (ohne Seitenang. und Heftzuteilung)
PB - Springer
CY - New York
ER -
TY - JOUR
A1 - Hamad, E. M.
A1 - Bilatto, S. E. R.
A1 - Adly, N. Y.
A1 - Correa, D. S.
A1 - Wolfrum, B.
A1 - Schöning, Michael Josef
A1 - Offenhäusser, A.
A1 - Yakushenko, A.
T1 - Inkjet printing of UV-curable adhesive and dielectric inks for microfluidic devices
JF - Lab on a Chip
N2 - Bonding of polymer-based microfluidics to polymer substrates still poses a challenge for Lab-On-a-Chip applications. Especially, when sensing elements are incorporated, patterned deposition of adhesives with curing at ambient conditions is required. Here, we demonstrate a fabrication method for fully printed microfluidic systems with sensing elements using inkjet and stereolithographic 3D-printing.
Y1 - 2016
U6 - https://doi.org/10.1039/C5LC01195G
SN - 1473-0189
VL - 16
IS - 1
SP - 70
EP - 74
PB - Royal Society of Chemistry
CY - Cambridge
ER -
TY - JOUR
A1 - Hamou, Hussam Aldin
A1 - Kotliar, Konstantin
A1 - Tan, Sonny Kian
A1 - Weiß, Christel
A1 - Blume, Christian
A1 - Clusmann, Hans
A1 - Schubert, Gerrit Alexander
A1 - Albanna, Walid
T1 - Surgical nuances and placement of subgaleal drains for supratentorial procedures—a prospective analysis of efficacy and outcome in 150 craniotomies
JF - Acta Neurochirurgica
N2 - Background
For supratentorial craniotomy, surgical access, and closure technique, including placement of subgaleal drains, may vary considerably. The influence of surgical nuances on postoperative complications such as cerebrospinal fluid leakage or impaired wound healing overall remains largely unclear. With this study, we are reporting our experiences and the impact of our clinical routines on outcome in a prospectively collected data set.
Method
We prospectively observed 150 consecutive patients undergoing supratentorial craniotomy and recorded technical variables (type/length of incision, size of craniotomy, technique of dural and skin closure, type of dressing, and placement of subgaleal drains). Outcome variables (subgaleal hematoma/CSF collection, periorbital edema, impairment of wound healing, infection, and need for operative revision) were recorded at time of discharge and at late follow-up.
Results
Early subgaleal fluid collection was observed in 36.7% (2.8% at the late follow-up), and impaired wound healing was recorded in 3.3% of all cases, with an overall need for operative revision of 6.7%. Neither usage of dural sealants, lack of watertight dural closure, and presence of subgaleal drains, nor type of skin closure or dressing influenced outcome. Curved incisions, larger craniotomy, and tumor size, however, were associated with an increase in early CSF or hematoma collection (p < 0.0001, p = 0.001, p < 0.01 resp.), and larger craniotomy size was associated with longer persistence of subgaleal fluid collections (p < 0.05).
Conclusions
Based on our setting, individual surgical nuances such as the type of dural closure and the use of subgaleal drains resulted in a comparable complication rate and outcome. Subgaleal fluid collections were frequently observed after supratentorial procedures, irrespective of the closing technique employed, and resolve spontaneously in the majority of cases without significant sequelae. Our results are limited due to the observational nature in our single-center study and need to be validated by supportive prospective randomized design.
Y1 - 2020
U6 - https://doi.org/10.1007/s00701-019-04196-6
SN - 0942-0940
VL - 2020
IS - 162
SP - 729
EP - 736
PB - Springer Nature
CY - Cham
ER -
TY - JOUR
A1 - Hanssen, H.
A1 - Nickel, T.
A1 - Drexel, V.
A1 - Hertel, G.
A1 - Emslander, I.
A1 - Sisic, Z.
A1 - Lorang, D.
A1 - Schuster, T.
A1 - Kotliar, Konstantin
A1 - Pressler, A.
A1 - Schmidt-Trucksäss, A.
A1 - Weis, M.
A1 - Halle, M.
T1 - Exercise-induced alterations of retinal vessel diameters and cardiovascular risk reduction in obesity
JF - Atherosclerosis
Y1 - 2011
SN - 0021-9150
VL - 216
IS - 2
SP - 433
EP - 439
PB - Elsevier
CY - Amsterdam
ER -
TY - JOUR
A1 - Harris, Isaac
A1 - Kleefeld, Andreas
T1 - Analysis and computation of the transmission eigenvalues with a conductive boundary condition
JF - Applicable Analysis
N2 - We provide a new analytical and computational study of the transmission eigenvalues with a conductive boundary condition. These eigenvalues are derived from the scalar inverse scattering problem for an inhomogeneous material with a conductive boundary condition. The goal is to study how these eigenvalues depend on the material parameters in order to estimate the refractive index. The analytical questions we study are: deriving Faber–Krahn type lower bounds, the discreteness and limiting behavior of the transmission eigenvalues as the conductivity tends to infinity for a sign changing contrast. We also provide a numerical study of a new boundary integral equation for computing the eigenvalues. Lastly, using the limiting behavior we will numerically estimate the refractive index from the eigenvalues provided the conductivity is sufficiently large but unknown.
KW - Boundary integral equations
KW - Inverse spectral problem
KW - Conductive boundary condition
KW - Transmission eigenvalues
Y1 - 2020
U6 - https://doi.org/10.1080/00036811.2020.1789598
SN - 1563-504X
VL - 101
IS - 6
SP - 1880
EP - 1895
PB - Taylor & Francis
CY - London
ER -
TY - JOUR
A1 - Harris, Isaac
A1 - Kleefeld, Andreas
T1 - The inverse scattering problem for a conductive boundary condition and transmission eigenvalues
JF - Applicable Analysis
N2 - In this paper, we consider the inverse scattering problem associated with an inhomogeneous media with a conductive boundary. In particular, we are interested in two problems that arise from this inverse problem: the inverse conductivity problem and the corresponding interior transmission eigenvalue problem. The inverse conductivity problem is to recover the conductive boundary parameter from the measured scattering data. We prove that the measured scatted data uniquely determine the conductivity parameter as well as describe a direct algorithm to recover the conductivity. The interior transmission eigenvalue problem is an eigenvalue problem associated with the inverse scattering of such materials. We investigate the convergence of the eigenvalues as the conductivity parameter tends to zero as well as prove existence and discreteness for the case of an absorbing media. Lastly, several numerical and analytical results support the theory and we show that the inside–outside duality method can be used to reconstruct the interior conductive eigenvalues.
KW - Transmission eigenvalues
KW - Conductive boundary condition
KW - Inverse scattering
Y1 - 2018
U6 - https://doi.org/10.1080/00036811.2018.1504028
SN - 1563-504X
VL - 99
IS - 3
SP - 508
EP - 529
PB - Taylor & Francis
CY - London
ER -
TY - JOUR
A1 - Hasan, Istabrak
A1 - Keil, Ludger
A1 - Staat, Manfred
A1 - Wahl, Gerhard
A1 - Bourauel, Christoph
T1 - Determination of the frictional coefficient of the implant-antler interface : experimental approach
JF - Biomedical Engineering / Biomedizinische Technik
N2 - The similar bone structure of reindeer antler to human bone permits studying the osseointegration of dental implants in the jawbone. As the friction is one of the major factors that have a significant influence on the initial stability of immediately loaded dental implants, it is essential to define the frictional coefficient of the implant-antler interface. In this study, the kinetic frictional forces at the implant-antler interface were measured experimentally using an optomechanical setup and a stepping motor controller under different axial loads and sliding velocities. The corresponding mean values of the static and kinetic frictional coefficients were within the range of 0.5–0.7 and 0.3–0.5, respectively. An increase in the frictional forces with increasing applied axial loads was registered. The measurements showed an evidence of a decrease in the magnitude of the frictional coefficient with increasing sliding velocity. The results of this study provide a considerable assessment to clarify the suitable frictional coefficient to be used in the finite element contact analysis of antler specimens.
Y1 - 2012
SN - 1862-278X
VL - 57
IS - 5
SP - 359
EP - 363
PB - De Gruyter
CY - Berlin
ER -
TY - JOUR
A1 - Hauser, C.
A1 - Kotliar, Konstantin
A1 - Tholen, S.
A1 - Hasenau, A.
A1 - Suttmann, Y.
A1 - Renders, L.
A1 - Heemann, U.
A1 - Baumann, M.
A1 - Schmaderer, C.
T1 - Dynamische retinale Gefäßreaktion bei Hämodialysepatienten
JF - Nieren- und Hochdruckkrankheiten
Y1 - 2015
U6 - https://doi.org/10.5414/NHX01743a
SN - 0300-5224
VL - 44
IS - 11
SP - 480
EP - 480
PB - Dustri-Verlag
CY - Oberhaching
ER -
TY - JOUR
A1 - Heel, Mareike van
A1 - Dikta, Gerhard
A1 - Braekers, Roel
T1 - Bootstrap based goodness‑of‑fit tests for binary multivariate regression models
JF - Journal of the Korean Statistical Society
N2 - We consider a binary multivariate regression model where the conditional expectation of a binary variable given a higher-dimensional input variable belongs to a parametric family. Based on this, we introduce a model-based bootstrap (MBB) for higher-dimensional input variables. This test can be used to check whether a sequence of independent and identically distributed observations belongs to such a parametric family. The approach is based on the empirical residual process introduced by Stute (Ann Statist 25:613–641, 1997). In contrast to Stute and Zhu’s approach (2002) Stute & Zhu (Scandinavian J Statist 29:535–545, 2002), a transformation is not required. Thus, any problems associated with non-parametric regression estimation are avoided. As a result, the MBB method is much easier for users to implement. To illustrate the power of the MBB based tests, a small simulation study is performed. Compared to the approach of Stute & Zhu (Scandinavian J Statist 29:535–545, 2002), the simulations indicate a slightly improved power of the MBB based method. Finally, both methods are applied to a real data set.
Y1 - 2021
U6 - https://doi.org/10.1007/s42952-021-00142-4
SN - 2005-2863 (Online)
SN - 1226-3192 (Print)
N1 - Corresponding author: Mareike van Heel
VL - 51
PB - Springer Nature
CY - Singapur
ER -
TY - JOUR
A1 - Heiden, W.
A1 - Turek, M.
A1 - Schöning, Michael Josef
T1 - TasteIT : Analyzing chemical sensor data using fuzzy logic
Y1 - 2011
SN - 978-1-4244-9910-6
N1 - 2011 IEEE Workshop on Merging Fields of Computational Intelligence and Sensor Technology ; 11.-15. April 2011 Paris, France
SP - 1
EP - 6
PB - IEEE
CY - New York
ER -
TY - JOUR
A1 - Heiden, W.
A1 - Turek, M.
A1 - Schöning, Michael Josef
T1 - Analysis of chemical sensor data
JF - Proceedings of the 4th Russian-German Workshop "Innovation Information Technologies: Theory and practice" : Ufa, Russia, April 8-13, 2011 / eds. Yupsova, Nafisa ...
Y1 - 2011
SN - 978-5-4221-0159-7
SP - 76
EP - 81
PB - State Aviation Technical Univ.
CY - Ufa
ER -
TY - JOUR
A1 - Heiduschka, P.
A1 - Romann, I.
A1 - Ecken, H.
A1 - Schöning, Michael Josef
A1 - Schuhmann, W.
A1 - Thanos, S.
T1 - Defined adhesion and growth of neurones on artificial structured substrates
JF - Scaling down in electrochemistry : electrochemical micro- and nanosystem technology ; proceedings of the 3rd International Symposium on Electrochemical Microsystem Technologies, Garmisch-Patenkirchen, Germany, 11 - 15 September 2000 / ed. by J. W. Schultz
Y1 - 2001
SN - 0-08-044014-2
SP - 299
EP - 307
PB - Elsevier [u.a.]
CY - Amsterdam [u.a.]
ER -
TY - JOUR
A1 - Heieis, Jule
A1 - Böcker, Jonas
A1 - D'Angelo, Olfa
A1 - Mittag, Uwe
A1 - Albracht, Kirsten
A1 - Schönau, Eckhard
A1 - Meyer, Andreas
A1 - Voigtmann, Thomas
A1 - Rittweger, Jörn
T1 - Curvature of gastrocnemius muscle fascicles as function of muscle–tendon complex length and contraction in humans
JF - Physiological Reports
N2 - It has been shown that muscle fascicle curvature increases with increasing contraction level and decreasing muscle–tendon complex length. The analyses were done with limited examination windows concerning contraction level, muscle–tendon complex length, and/or intramuscular position of ultrasound imaging. With this study we aimed to investigate the correlation between fascicle arching and contraction, muscle–tendon complex length and their associated architectural parameters in gastrocnemius muscles to develop hypotheses concerning the fundamental mechanism of fascicle curving. Twelve participants were tested in five different positions (90°/105°*, 90°/90°*, 135°/90°*, 170°/90°*, and 170°/75°*; *knee/ankle angle). They performed isometric contractions at four different contraction levels (5%, 25%, 50%, and 75% of maximum voluntary contraction) in each position. Panoramic ultrasound images of gastrocnemius muscles were collected at rest and during constant contraction. Aponeuroses and fascicles were tracked in all ultrasound images and the parameters fascicle curvature, muscle–tendon complex strain, contraction level, pennation angle, fascicle length, fascicle strain, intramuscular position, sex and age group were analyzed by linear mixed effect models. Mean fascicle curvature of the medial gastrocnemius increased with contraction level (+5 m−1 from 0% to 100%; p = 0.006). Muscle–tendon complex length had no significant impact on mean fascicle curvature. Mean pennation angle (2.2 m−1 per 10°; p < 0.001), inverse mean fascicle length (20 m−1 per cm−1; p = 0.003), and mean fascicle strain (−0.07 m−1 per +10%; p = 0.004) correlated with mean fascicle curvature. Evidence has also been found for intermuscular, intramuscular, and sex-specific intramuscular differences of fascicle curving. Pennation angle and the inverse fascicle length show the highest predictive capacities for fascicle curving. Due to the strong correlations between pennation angle and fascicle curvature and the intramuscular pattern of curving we suggest for future studies to examine correlations between fascicle curvature and intramuscular fluid pressure.
KW - biomechanics
KW - connective tissue
KW - physiology
KW - ultrasound
Y1 - 2023
U6 - https://doi.org/10.14814/phy2.15739
SN - 2051-817X
VL - 11
IS - 11
SP - e15739, Seite 1-11
PB - Wiley
ER -
TY - JOUR
A1 - Heinke, Lars N.
A1 - Knicker, Axel J.
A1 - Albracht, Kirsten
T1 - Evaluation of passively induced shoulder stretch reflex using an isokinetic dynamometer in male overhead athletes
JF - Isokinetics and Exercise Science
N2 - BACKGROUND: Muscle stretch reflexes are widely considered to beneficially influence joint stability and power generation in the lower limbs. While in the upper limbs and especially in the muscles surrounding the shoulder joint such evidence is lacking. OBJECTIVE: To quantify the electromyographical response in the muscles crossing the shoulder of specifically trained overhead athletes to an anterior perturbation force. METHODS: Twenty healthy male participants performed six sets of different external shoulder rotation stretches on an isokinetic dynamometer over a range of amplitudes and muscle pre-activation moment levels. All stretches were applied with a dynamometer acceleration of 10,000∘/s2 and a velocity of 150∘/s. Electromyographical response was measured via sEMG. RESULTS: Consistent reflexes were not observed in all experimental conditions. The reflex latencies revealed a significant muscle main effect (F (2,228) = 99.31, p< 0.001; η2= 0.466; f= 0.934) and a pre-activation main effect (F (1,228) = 142.21, p< 0.001; η2= 0.384; f= 1.418). The stretch reflex amplitude yielded a significant pre-activation main effect (F (1,222) = 470.373, p< 0.001; η2= 0.679; f= 1.454). CONCLUSION: Short latency muscle reflexes showed a tendency to an anterior to posterior muscle recruitment whereby the main internal rotator muscles of the shoulder revealed the most consistent results.
Y1 - 2018
U6 - https://doi.org/10.3233/IES-184111
SN - 1878-5913
VL - 26
IS - 4
SP - 265
EP - 274
PB - IOS Press
CY - Amsterdam
ER -
TY - JOUR
A1 - Heinke, Lars N.
A1 - Knicker, Axel J.
A1 - Albracht, Kirsten
T1 - Increased shoulder muscle stretch reflex elicitability in supine subject posture
JF - Isokinetics and Exercise Science
N2 - BACKGROUND: Muscle stretch reflexes are widely used to examine neural muscle function. The knowledge of reflex response in muscles crossing the shoulder is limited. OBJECTIVE: To quantify reflex modulation according to various subject postures and different procedures of muscle pre-activation steering. METHODS: Thirteen healthy male participants performed two sets of external shoulder rotation stretches in various positions and with different procedures of muscle pre-activation steering on an isokinetic dynamometer over a range of two different pre-activation levels. All stretches were applied with a dynamometer acceleration of 104∘/s2 and a velocity of 150∘/s. Electromyographical response was measured via sEMG. RESULTS: Consistent reflexive response was observed in all tested muscles in all experimental conditions. The reflex elicitation rate revealed a significant muscle main effect (F (5,288) = 2.358, ρ= 0.040; η2= 0.039; f= 0.637) and a significant test condition main effect (F (1,288) = 5.884, ρ= 0.016; η2= 0.020; f= 0.143). Reflex latency revealed a significant muscle pre-activation level main effect (F (1,274) = 5.008, ρ= 0.026; η2= 0.018; f= 0.469). CONCLUSION: Muscular reflexive response was more consistent in the primary internal rotators of the shoulder. Supine posture in combination with visual feedback of muscle pre-activation level enhanced the reflex elicitation rate.
Y1 - 2020
U6 - https://doi.org/10.3233/IES-192219
SN - 1878-5913
VL - 28
IS - 2
SP - 139
EP - 146
PB - IOS Press
CY - Amsterdam
ER -
TY - JOUR
A1 - Heinke, Lars N.
A1 - Knicker, Axel J.
A1 - Albracht, Kirsten
T1 - Test-retest reliability of the internal shoulder rotator muscles' stretch reflex in healthy men
JF - Journal of Electromyography and Kinesiology
N2 - Until now the reproducibility of the short latency stretch reflex of the internal rotator muscles of the glenohumeral joint has not been identified. Twenty-three healthy male participants performed three sets of external shoulder rotation stretches with various pre-activation levels on two different dates of measurement to assess test-retest reliability. All stretches were applied with a dynamometer acceleration of 104°/s2 and a velocity of 150°/s. Electromyographical response was measured via surface EMG. Reflex latencies showed a pre-activation effect (ƞ2 = 0,355). ICC ranged from 0,735 to 0,909 indicating an overall “good” relative reliability. SRD 95% lay between ±7,0 to ±12,3 ms.. The reflex gain showed overall poor test-retest reproducibility. The chosen methodological approach presented a suitable test protocol for shoulder muscles stretch reflex latency evaluation. A proof-of-concept study to validate the presented methodical approach in shoulder involvement including subjects with clinically relevant conditions is recommended.
KW - stretch reflex
KW - shoulder
KW - test-retest reliability
KW - intraclass correlation coefficient
KW - standard error of measurement
Y1 - 2021
U6 - https://doi.org/10.1016/j.jelekin.2021.102611
SN - 1050-6411
VL - 62
IS - Article 102611
PB - Elsevier
CY - Amsterdam
ER -
TY - JOUR
A1 - Heinrich, U.
A1 - Blum, A.
A1 - Bussmann, N.
A1 - Engels, R.
A1 - Kemmerling, G.
A1 - Weber, S.
A1 - Ziemons, Karl
T1 - Statistical studies on the light output and energy resolution of small LSO single crystals with different surface treatments combined with various reflector materials
JF - Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
N2 - The optimization of light output and energy resolution of scintillators is of special interest for the development of high resolution and high sensitivity PET. The aim of this work is to obtain statistically reliable results concerning optimal surface treatment of scintillation crystals and the selection of reflector material. For this purpose, raw, mechanically polished and etched LSO crystals (size 2×2×10 mm3) were combined with various reflector materials (Teflon tape, Teflon matrix, BaSO4) and exposed to a 22Na source. In order to ensure the statistical reliability of the results, groups of 10 LSO crystals each were measured for all combinations of surface treatment and reflector material. Using no reflector material the light output increased up to 551±35% by mechanical polishing the surface compared to 100±5% for raw crystals. Etching the surface increased the light output to 441±29%. The untreated crystals had an energy resolution of 24.6±4.0%. By mechanical polishing the surface it was possible to achieve an energy resolution of 13.2±0.8%, by etching of 14.8±0.7%. In combination with BaSO4 as reflector material the maximum increase of light output has been established to 932±57% for mechanically polished and 895±61% for etched crystals. The combination with BaSO4 also caused the best improvement of the energy resolution up to 11.6±0.2% for mechanically polished and 12.2±0.3% for etched crystals. Relating to the light output there was no significant statistical difference between the two surface treatments in combination with BaSO4. In contrast to this, the statistical results of the energy resolution have shown the combination of mechanical polishing and BaSO4 as the optimum.
Y1 - 2002
SN - 0168-9002
N1 - Proceedings of the 6th International Conference on Inorganic Scin tillators and their Use in Scientific and Industrial Applications
VL - 486
IS - 1-2
SP - 60
EP - 66
ER -
TY - JOUR
A1 - Heinrichs, U.
A1 - Pietrzyk, Uwe
A1 - Ziemons, Karl
T1 - Design optimization of the PMT-ClearPET prototypes based on simulation studies with GEANT3
JF - IEEE Transactions on Nuclear Science
N2 - Within the Crystal Clear Collaboration (CCC), four centers are developing second generation high performance small animal positron emission tomography (PET) scanners for different kinds of animals and medical applications. The first prototypes are photomultiplier tube (PMT)-based systems including depth of interaction (DOI) detection by using a phoswich layer of lutetium oxyorthosilicate (LSO) and lutetium yttrium aluminum perovskite (LuYAP). The aim of these simulation studies is to optimize sensitivity and spatial resolution of given designs, which vary in fields of view (FOVs) caused by different detector configurations (ring/octagon) and sizes. For this purpose the simulation tool GEANT3 (CERN, Geneva, Switzerland) was used.
Y1 - 2003
SN - 0018-9499
VL - 50
IS - 5
SP - 1428
EP - 1432
ER -
TY - JOUR
A1 - Heinzel, Alexander
A1 - Schäfer, Ralf
A1 - Müller, Hans-Wilhelm
A1 - Schieffer, Andre
A1 - Ingenhag, Ariane
A1 - Eickhoff, Simon B.
A1 - Northoff, Georg
A1 - Franz, Matthias
A1 - Hautzel, Hubertus
T1 - Increased Activation of the Supragenual Anterior Cingulate Cortex during Visual Emotional Processing in Male Subjects with High Degrees of Alexithymia: An Event-Related fMRI Study
JF - Psychotherapy and Psychosomatics
N2 - Background: One of the most prominent neurobiological models of alexithymia assumes an altered function of the anterior cingulate cortex (ACC) as the crucial neural correlate of alexithymia. So far functional imaging studies have yielded inconclusive results. Therefore, we tested this hypothesis in healthy alexithymics and nonalexithymics in an event-related fMRI study.
Methods: Thirty high- and 30 low-alexithymic right-handed male subjects (selected by the 20-item Toronto Alexithymia Scale, TAS-20) were investigated with event-related fMRI using a picture viewing paradigm. The stimuli consisted of happy, fearful and neutral facial expressions (Ekman-Friesen) as well as positive, negative and neutral pictures from the International Affective Picture System.
Results: Contrasting the high-alexithymic with the low-alexithymic group we observed increased activation of the supragenual ACC for different emotional valences as well as for different emotional stimuli. Moreover, there was a positive correlation of the ACC with the individual TAS-20 scores but no correlations with the individual Beck Depression Inventory scores. Additionally, there was no difference in activity of the amygdala.
Conclusions: We demonstrated that the supragenual ACC is constantly activated more strongly in alexithymic subjects and that this activation is related to the symptoms of alexithymia and not to associated symptoms such as depression. Therefore, our findings support the hypothesis of an altered function of the ACC in alexithymia.
Y1 - 2010
U6 - https://doi.org/10.1159/000320121
SN - 0033-3190
VL - 79
IS - 6
SP - 363
EP - 370
PB - Karger
CY - Basel
ER -
TY - JOUR
A1 - Heinzel, Alexander
A1 - Schäfer, Ralf
A1 - Müller, Hans-Wilhelm
A1 - Schieffer, Andre
A1 - Ingenhag, Ariane
A1 - Northoff, Georg
A1 - Franz, Matthias
A1 - Hautzel, Hubertus
T1 - Differential modulation of valence and arousal in high-alexithymic and low-alexithymic individuals
JF - Neuroreport
N2 - High-alexithymic individuals are characterized by an impaired ability to identify and communicate emotions whereas low-alexithymic individuals have a wide-ranging ability to deal with emotions. This study examined the hypothesis that valence and arousal modifications of emotional stimuli differentially modulate cortical regions in high-alexithymic and low-alexithymic individuals. To this end, 28 high-alexithymic and 25 low-alexithymic individuals were investigated with event-related fMRI using visual emotional stimuli. We found differential neural activations in the dorsal anterior cingulate, the insula and the amygdala. We suggest that these differences may account for the impaired ability of high-alexithymic individuals to appropriately handle emotional stimuli.
Y1 - 2010
U6 - https://doi.org/10.1097/WNR.0b013e32833f38e0
SN - 1473-558X
VL - 21
IS - 15
SP - 998
EP - 1002
PB - Lippincott Williams & Wilkins
CY - London
ER -
TY - JOUR
A1 - Hekmat, Khosro
A1 - Kanani, Reza
A1 - Lauterbach, Gerhard
A1 - Südkamp, Michael
A1 - Ahmadpoor, Tooraj
A1 - Weber, Hans-Joachim
A1 - Mehlhorn, Uwe
T1 - Moderne Herzschrittmachersysteme wenig störanfällig durch Mobilfunktelefone
JF - Deutsches Ärzteblatt. 100 (2003), H. 38
Y1 - 2003
SP - A2438
EP - A2445
ER -
TY - JOUR
A1 - Hekmat, Khosro
A1 - Salemink, B.
A1 - Lauterbach, Gerhard
A1 - Schwinger, R. H. G.
A1 - Südkamp, M.
A1 - Weber, Hans-Joachim
A1 - Mehlhorn, U.
T1 - Interference by cellular phones with permanent implanted pacemakers: an update
JF - Europace. 6 (2004), H. 4
Y1 - 2004
SP - 363
EP - 369
ER -
TY - JOUR
A1 - Hennemann, Jörg
A1 - Kohl, Claus-Dieter
A1 - Reisert, Steffen
A1 - Kirchner, Patrick
A1 - Schöning, Michael Josef
T1 - Copper oxide nanofibres for detection of hydrogen peroxide vapour at high concentrations
JF - physica status solidi (a)
N2 - We present a sensor concept based on copper(II)oxide (CuO) nanofibres for the detection of hydrogen peroxide (H2O2) vapour in the percent per volume (% v/v) range. The fibres were produced by using the electrospinning technique. To avoid water condensation in the pores, the fibres were initially modified by an exposure to H2S to get an enclosed surface. By a thermal treatment at 350 °C the fibres were oxidised back to CuO. Thereby, the visible pores disappear which was verified by SEM analysis. The fibres show a decrease of resistance with increasing H2O2 concentration which is due to the fact that hydrogen peroxide is an oxidising gas and CuO a p-type semiconductor. The sensor shows a change of resistance within the minute range to the exposure until the maximum concentration of 6.9% v/v H2O2. At operating temperatures below 450 °C the corresponding sensor response to a concentration of 4.1% v/v increases. The sensor shows a good reproducibility of the signal at different measurements. CuO seems to be a suitable candidate for the detection of H2O2 vapour at high concentrations.
Resistance behaviour of the sensor under exposure to H2O2 vapours between 2.3 and 6.9% v/v at an operating temperature of 450 °C.
Y1 - 2013
U6 - https://doi.org/10.1002/pssa.201200775
SN - 1862-6319
VL - 210
IS - 5
SP - 859
EP - 863
PB - Wiley
CY - Weinheim
ER -
TY - JOUR
A1 - Herber, R.
A1 - Ernst, S.
A1 - Buß, G.
A1 - Schöning, Michael Josef
A1 - Baltruschat, H.
T1 - Detection of hydrocarbons in air and water by adsorption on Pt electrodes using continuous impedance measurements
JF - Proceedings of the Symposium on New Directions in Electroanalytical Chemistry II : [held at the 195th Meeting of the Electrochemical Society in Seattle, Washington on May 3 and 4, 1999] / Physical Electrochemistry, Sensor, and Organic and Biological Electrochemistry Divisions. Ed.: J. Leddy, P. Vanysek, M.D. Porter
Y1 - 1999
SN - 1-56677-227-3
N1 - Symposium on New Directions in Electroanalytical Chemistry ; (2, 1999, Seattle, Wash.)
SP - 168
EP - 177
PB - Electrochemical Society
CY - Pennington, NJ
ER -
TY - JOUR
A1 - Herssens, Nolan
A1 - Cowburn, James
A1 - Albracht, Kirsten
A1 - Braunstein, Bjoern
A1 - Cazzola, Dario
A1 - Colyer, Steffi
A1 - Minetti, Alberto E.
A1 - Pavei, Gaspare
A1 - Rittweger, Jörn
A1 - Weber, Tobias
A1 - Green, David A.
ED - Cattaneo, Luigi
T1 - Movement in low gravity environments (MoLo) programme – the MoLo-L.O.O.P. study protocol
JF - PLOS ONE / Public Library of Science
N2 - Exposure to prolonged periods in microgravity is associated with deconditioning of the musculoskeletal system due to chronic changes in mechanical stimulation. Given astronauts will operate on the Lunar surface for extended periods of time, it is critical to quantify both external (e.g., ground reaction forces) and internal (e.g., joint reaction forces) loads of relevant movements performed during Lunar missions. Such knowledge is key to predict musculoskeletal deconditioning and determine appropriate exercise countermeasures associated with extended exposure to hypogravity.
Y1 - 2022
U6 - https://doi.org/10.1371/journal.pone.0278051
SN - 1932-6203
VL - 17
IS - 11
PB - Plos
CY - San Francisco
ER -
TY - JOUR
A1 - Herzog, Hans
A1 - Pietrzyk, Uwe
A1 - Shah, N. Jon
A1 - Ziemons, Karl
T1 - The current state, challenges and perspectives of MR-PET
JF - Neuroimage
N2 - Following the success of PET/CT during the last decade and the recent increasing proliferation of SPECT/CT, another hybrid imaging instrument has been gaining more and more interest: MR-PET. First combined, simultaneous PET and MR studies carried out in small animals demonstrated the feasibility of the new approach. Concurrently, some prototypes of an MR-PET scanner for simultaneous human brain studies have been built, their performance is being tested and preliminary applications have already been shown. Through this pioneering work, it has become clear that advances in the detector design are necessary for further optimization.
Recently, the different issues related to the present state and future prospects of MR-PET were presented and discussed during an international 2-day workshop at the Forschungszentrum Jülich, Germany, held after, and in conjunction with, the 2008 IEEE Nuclear Science Symposium and Medical Imaging Conference in Dresden, Germany on October 27–28, 2008. The topics ranged from small animal MR-PET imaging to human MR-BrainPET imaging, new detector developments, challenges/opportunities for ultra-high field MR-PET imaging and considerations of possible future research and clinical applications. This report presents a critical summary of the contributions made to the workshop.
Y1 - 2010
U6 - https://doi.org/10.1016/j.neuroimage.2009.10.036
SN - 1053-8119
VL - 49
IS - 3
SP - 2072
EP - 2082
PB - Elsevier
CY - Amsterdam
ER -
TY - JOUR
A1 - Hillen, Walter
T1 - Properties of hadron final states in e+e− annihilation at 13 GeV and 17 GeV center of mass energies. TASSO Collaboration
JF - Physics Letters B. 83 (1979), H. 2
Y1 - 1979
SN - 0370-2693
SP - 261
EP - 266
ER -
TY - JOUR
A1 - Hillen, Walter
T1 - Bildrestauration in der digitalen Radiographie mit Hilfe parallel arbeitender Signalprozessoren
JF - Parallele Datenverarbeitung : Entwurfsmethoden, Bildverarbeitung, Simulation ; Workshop der Arbeitsgemeinschaft "Parallelverarbeitung an Fachhochschulen in NRW" am 19.6.1998 in Bochum / Jörg Krone ... (Hrsg.)
Y1 - 1998
SN - 3-18-355310-4
N1 - Fortschritt-Berichte VDI : Reihe 10, Informatik, Kommunikationstechnik ; 553
SP - 78
EP - 87
PB - VDI-Verl.
CY - Düsseldorf
ER -
TY - JOUR
A1 - Hillen, Walter
T1 - A measurement of σtot(e+e− → hadrons) for cm energies between 12.0 and 36.7 GeV. TASSO Collaboration
JF - Physics Letters B. 113 (1982), H. 6
Y1 - 1982
SP - 499
EP - 508
ER -
TY - JOUR
A1 - Hillen, Walter
T1 - Scale braking in inclusive charged particle production by e--e+ annihilation. TASSO Collaboration
JF - Physics Letters B. 114 (1982), H. 1
Y1 - 1982
SN - 0370-2693
SP - 65
EP - 70
ER -
TY - JOUR
A1 - Hillen, Walter
T1 - Charged pion production in e--e+ annihilation at 14, 22 and 34 GeV c.m. energies. TASSO Collaboration
JF - Physics Letters B. 113 (1982), H. 1
Y1 - 1982
SN - 0370-2693
SP - 98
EP - 104
ER -
TY - JOUR
A1 - Hillen, Walter
T1 - Charged pion, kaon, proton and antiproton production in high energy e+e− annihilations. TASSO Collaboration
JF - Physics Letters B. 94 (1980), H. 3
Y1 - 1980
SN - 0370-2693
SP - 444
EP - 449
ER -
TY - JOUR
A1 - Hillen, Walter
T1 - Comparison of e+e− annihilation with QCD and determination of the strong coupling constant . TASSO Collaboration
JF - Physics Letters B. 94 (1980), H. 3
Y1 - 1980
SN - 0370-2693
SP - 437
EP - 443
ER -
TY - JOUR
A1 - Hillen, Walter
T1 - K0 production in e+e− annihilations at 30 GeV center of mass energy. TASSO Collaboration
JF - Physics Letters B. 94 (1980), H. 1
Y1 - 1980
SN - 0370-2693
SP - 91
EP - 95
ER -
TY - JOUR
A1 - Hillen, Walter
T1 - Test of QED in e+e− annihilation at energies between 12 and 31.6 GeV. TASSO Collaboration
JF - Physics Letters B. 94 (1980), H. 2
Y1 - 1980
SN - 0370-2693
SP - 259
EP - 265
ER -
TY - JOUR
A1 - Hillen, Walter
T1 - Rapid growth of charged particle multiplicity in high energy e+e− annihilations. TASSO Collaboration
JF - Physics Letters B. 89 (1980), H. 3-4
Y1 - 1980
SN - 0370-2693
SP - 418
EP - 422
ER -
TY - JOUR
A1 - Hillen, Walter
T1 - Production and properties of the τ-lepton in e+e− annihilation at C.M. energies from 12 to 31.6 GeV. TASSO Collaboration
JF - Physics Letters B. 92 (1980), H. 1-2
Y1 - 1980
SN - 0370-2693
SP - 199
EP - 205
ER -
TY - JOUR
A1 - Hillen, Walter
T1 - Evidence for planar events in e+e− annihilation at high energies. TASSO Collaboration
JF - Physics Letters B. 86 (1979), H. 2
Y1 - 1979
SN - 0370-2693
SP - 243
EP - 249
ER -
TY - JOUR
A1 - Hillen, Walter
T1 - Energy scan for narrow states in e+e− annihilation at C.M. energies between 29.90 and 31.46 GeV. TASSO Collaboration
JF - Physics Letters B. 88 (1979), H. 1-2
Y1 - 1979
SN - 0370-2693
SP - 199
EP - 202
ER -
TY - JOUR
A1 - Hillen, Walter
T1 - Charge asymmetry and weak interaction effects in e+e−→μ+μ− and e+e−→τ+τ− . TASSO Collaboration
JF - Physics Letters B. 110 (1982), H. 2
Y1 - 1982
SN - 0370-2693
SP - 173
EP - 180
ER -
TY - JOUR
A1 - Hillen, Walter
T1 - π0 production by e+e− annihilation at 14 and 34 GeV c.m. energy . TASSO Collaboration
JF - Physics Letters B. 108 (1982), H. 1
Y1 - 1982
SN - 0370-2693
SP - 71
EP - 76
ER -
TY - JOUR
A1 - Hillen, Walter
T1 - Exclusive proton-antiproton production in two photon collisions . TASSO Collaboration
JF - Physics Letters B. 108 (1982), H. 1
Y1 - 1982
SN - 0370-2693
SP - 67
EP - 70
ER -
TY - JOUR
A1 - Hillen, Walter
T1 - High pT hadron production in photon-photon collisions . TASSO Collaboration
JF - Physics Letters B. 107 (1982), H. 4
Y1 - 1982
SN - 0370-2693
SP - 290
EP - 296
ER -
TY - JOUR
A1 - Hillen, Walter
T1 - Λ, Image production in e+e- annihilation at 33 GeV centre of mass energy. TASSO Collaboration
JF - Physics Letters B. 105 (1981), H. 4
Y1 - 1981
SN - 0370-2693
SP - 75
EP - 80
ER -
TY - JOUR
A1 - Hillen, Walter
T1 - Evidence for charged primary partons in e+e− → 2 jets. TASSO Collaboration
JF - Physics Letters B. 100 (1981), H. 4
Y1 - 1981
SN - 0370-2693
SP - 357
EP - 363
ER -
TY - JOUR
A1 - Hillen, Walter
T1 - Search for new sequential leptons in e+e- annihilation at petra energies. TASSO Collaboration
JF - Physics Letters B. 99 (1981), H. 2
Y1 - 1981
SN - 0370-2693
SP - 163
EP - 168
ER -
TY - JOUR
A1 - Hillen, Walter
T1 - Evidence for a spin-1 gluon in three-jet events. TASSO Collaboration
JF - Physics Letters B. 97 (1980), H. 3-4
Y1 - 1980
SN - 0370-2693
SP - 453
EP - 458
ER -
TY - JOUR
A1 - Hillen, Walter
T1 - RHO-RHO production by two photon scattering. TASSO Collaboration
JF - Physics Letters B. 97 (1980), H. 3-4
Y1 - 1980
SN - 0370-2693
SP - 448
EP - 452
ER -
TY - JOUR
A1 - Hillen, Walter
A1 - Alper Selver, M.
A1 - Fischer, Felix
A1 - Kuntalp, Mehmet
T1 - A software tool for interactive generation, representation, and systematical storage of transfer functions for 3D medical images / Alper Selver, M. ; Fischer, Felix ; Kuntalp, Mehmet ; Hillen, Walter
JF - Computer Methods and Programs in Biomedicine. 86 (2007), H. 3
Y1 - 2007
SN - 0169-2607
SP - 270
EP - 280
PB - -
ER -
TY - JOUR
A1 - Hillen, Walter
A1 - Barry, J. C.
A1 - Pongs, U. M.
T1 - Algorithm for Purkinje Image I and IV and Limbus Centre Location. Barry, J. C.; Pongs, U. M.; Hillen, W.
JF - Computers in Biology and Medicine. 27 (1997), H. 6
Y1 - 1997
SN - 0010-4825
SP - 515
EP - 531
ER -
TY - JOUR
A1 - Hillen, Walter
A1 - Eckenbach, W.
A1 - Quadflieg, Peter
A1 - Zaengel, Thomas T.
T1 - Signal-to-noise performance of a CsI fluorescent screen
JF - Medical Imaging V: Image physics
Y1 - 1991
SN - 0-8194-0538-8
N1 - Proceedings of SPIE ; 1443
SP - 120
EP - 131
ER -
TY - JOUR
A1 - Hillen, Walter
A1 - Fischer, Felix
T1 - Farbanalyse von gebackenen oder frittierten Nahrungsmitteln und Vorhersage des Acrylamid-Wertes
JF - 10. Workshop Farbbildverarbeitung : Elektronische Ressource : 7.-8. Oktober 2004, Koblenz = 10th Workshop Color Image Processing / Detlev Droege ... Hrsg.
Y1 - 2004
SN - 389959245X
N1 - Workshop Farbbildverarbeitung <10, 2004, Koblenz>
SP - 133
EP - 148
PB - Der Andere Verl.
CY - Tönning [u.a.]
ER -
TY - JOUR
A1 - Hillen, Walter
A1 - Fischer, Felix
A1 - Paulus, Dietrich
T1 - 3D Presentation States: Parametrisierung und Speicherung der 3D-Darstellung von segmentierten medizinischen Volumendaten / Fischer, Felix ; Hillen, Walter ; Paulus, Dietrich
JF - Biomedizinische Technik. 52 (2007), H. Ergänzungsband
Y1 - 2007
SN - 0939-4990
N1 - BMT 2007, 41. Jahrestagung der DGBMT - Deutschen Gesellschaft für Biomedizinische Technik im VDE, Aachen, DE, 26.-29. Sep, 2007
SP - 1
EP - 2
ER -
TY - JOUR
A1 - Hillen, Walter
A1 - Jansen, N.
A1 - Unglauben, F.
A1 - Indefrey, R.
T1 - Multimediale Darstellung und Verarbeitung medizinischer Bilddaten in Rechnernetzen.
JF - Bildverarbeitung für die Medizin 1998 : Algorithmen - Systeme - Anwendungen ; proceedings des Workshops am 26. und 27. März 1998 in Aachen / Thomas Lehmann ... (Hrsg.)
Y1 - 1998
SN - 3540638857
N1 - Workshop Bildverarbeitung für die Medizin ; <1998, Aachen> Inhaltsverzeichnis
SP - 373
EP - 377
PB - Springer
CY - Berlin [u.a.]
ER -
TY - JOUR
A1 - Hillen, Walter
A1 - Lehmann, T.
A1 - Horn, H.
A1 - Schmitt, W.
T1 - IDEFIX - Identifizierung dentaler Fixturen mit morphologischen Filtern. Lehmann, T.; Horn, H.; Schmitt, W., Hillen, W.; Spitzer, K.
JF - Bildverarbeitung für die Medizin : Algorithmen - Systeme - Anwendungen ; proceedings des Aachener Workshops am 8. und 9. November 1996 / Institut für Medizinische Informatik und Biometrie der RWTH Aachen. Hrsg. von Thomas Lehmann ...
Y1 - 1996
SN - 3-86073-519-5
SP - 327
EP - 332
PB - Verl. der Augustinus-Buchh.
CY - Aachen
ER -
TY - JOUR
A1 - Hillen, Walter
A1 - Lehmann, T.
A1 - Horn, H.
A1 - Schmitt, W.
T1 - Identification of Dental Fixtures in Intraoral X-rays. Lehmann, T.; Hillen, W.; Horn, H.; Schmitt, W.
JF - Medical imaging 1996 : image processing ; 12 - 15 February 1996, Newport Beach, California / Murray H. Loew ... chairs/ed.
Y1 - 1996
SN - 0-8194-2085-9
N1 - Proceedings of SPIE; 2710
SP - 584
EP - 584
PB - SPIE - The International Society for Optical Engineering
CY - Bellingham, Wash.
ER -
TY - JOUR
A1 - Hillen, Walter
A1 - Lehmann, T.
A1 - Horn, H.
A1 - Schmitt, W.
T1 - IDEFIX - Identification of Dental Fixtures. Lehmann, T.; Hillen, W.; Horn, H.; Schmitt, W.
JF - 5th European Congress on Dental and Maxillo-Facial Radiology : 30th Annual meeting of Working Group for Dental Radiology in the German Scientific Society for Dentistry, November 8-11, 1995, Cologne : abstracts
Y1 - 1995
N1 - European Congress on Dental and Maxillo-Facial Radiology <5, 1995, Köln>
ER -
TY - JOUR
A1 - Hillen, Walter
A1 - Rupp, S.
A1 - Schiebel, U.
A1 - Zaengel, Thomas T.
T1 - Imaging performance of a selenium-based detector for high-resolution radiography
JF - Medical Imaging III: Image Formation
Y1 - 1989
SN - 0-8194-0125-0
N1 - Proceedings of SPIE ; 1090
SP - 296
ER -
TY - JOUR
A1 - Hillen, Walter
A1 - Schiebel, U.
A1 - Zaengel, T.
T1 - A selenium-based detector for digital slot-radiography
JF - Medical Imaging II
Y1 - 1988
N1 - Proceedings of SPIE ; 914
SP - 253
ER -
TY - JOUR
A1 - Hillen, Walter
A1 - Schiebel, U.
A1 - Zaengel, T.
T1 - Image quality in selenium-based digital radiography. Schiebel, U.; Hillen, W.; Zaengel, T.
JF - Medical Imaging
Y1 - 1986
N1 - Proceedings of SPIE ; 626
SP - 176
ER -
TY - JOUR
A1 - Hillen, Walter
A1 - Schiebel, U.
A1 - Zaengel, T.
T1 - Imaging performance of a digital storage phosphor system
JF - Medical Physics. 14 (1987), H. 5
Y1 - 1987
SN - 0094-2405
SP - 744
EP - 751
ER -
TY - JOUR
A1 - Hillen, Walter
A1 - Schmitt, W.
A1 - Bockemühl, J.
T1 - Signal-to-Noise Performance of a digital dental X-ray Detector
JF - Computer assisted radiology : proceedings of the International Symposium on Computer and Communication Systems for Image Guided Diagnosis and Therapy / CAR '95 Berlin, June 21 - 24, 1995. Ed. by H. U. Lemke
Y1 - 1995
SN - 3-540-59177-X
N1 - CAR <6, 1995, Berlin>
PB - Springer
CY - Berlin [u.a.]
ER -
TY - JOUR
A1 - Hillen, Walter
A1 - Unglauben, F.
A1 - Indefrey, F.
T1 - Java Image Viewer zur Darstellung und Verarbeitung medizinischer Bilddaten in Rechnernetzen
JF - Intelligente, innovative Produktentwicklung für die industrielle Praxis. Stenzel, Horst [Hrsg.]
Y1 - 2001
N1 - Forschungsverbund Multimedia an Fachhochschulen in Nordrhein-Westfalen
SP - 23
EP - 28
PB - Forschungverbund Multimedia an Fachhochschulen
CY - Köln
ER -
TY - JOUR
A1 - Hillen, Walter
A1 - Unglauben, F.
A1 - Kondring, T.
T1 - Java DICOM Viewer für die Teleradiologie. Unglauben, F.; Hillen, W.; Kondring, T.
JF - Bildverarbeitung für die Medizin 2001 : Algorithmen, Systeme, Anwendungen ; proceedings des Workshops [Bildverarbeitung für die Medizin] vom 4. - 6. März 2001 in Lübeck / Heinz Handels ... [Hrsg.]
Y1 - 2001
SN - 3-540-41690-0
N1 - Inhaltsverzeichnis; Workshop Bildverarbeitung für die Medizin <2001, Lübeck>
SP - 404
EP - 408
PB - Springer
CY - Berlin [u.a.]
ER -
TY - JOUR
A1 - Hillen, Walter
A1 - Unglauben, F.
A1 - Murdfield, M.
T1 - Study of Database Connections for a Java Medical Image Viewer. Unglauben, F.; Hillen, W.; Murdfield, M.
JF - Intelligente, innovative Produktentwicklung für die industrielle Praxis. Blümel, Bernd; Stenzel, Horst [Hrsg.]
Y1 - 2001
N1 - Forschungsverbund Multimedia an Fachhochschulen in Nordrhein-Westfalen
SP - 29
EP - 33
PB - Forschungverbund Multimedia an Fachhochschulen
CY - Köln
ER -
TY - JOUR
A1 - Hillen, Walter
A1 - Unglauben, F.
A1 - Murdfield, M.
T1 - Evaluation of two- and three-tier database connections for a java-based medical image viewer. Unglauben, F.; Hillen, W.; Murdfield, M.
JF - Bildverarbeitung für die Medizin 2000 : Algorithmen - Systeme - Anwendungen ; proceedings des Workshops [Bildverarbeitung für die Medizin] vom 12. - 14. März 2000 in München / Alexander Horsch ... [Hrsg.]
Y1 - 2000
SN - 3-540-67123-4
N1 - Inhaltsverzeichnis; Workshop Bildverarbeitung für die Medizin <2000, München>
SP - 203
EP - 207
PB - Springer
CY - Berlin [u.a.]
ER -
TY - JOUR
A1 - Hillen, Walter
A1 - Unglauben, F.
A1 - Wirtz, G.
T1 - Architectures and Modeling of Distributed Image Information Systems. Unglauben, F.; Hillen, W.; Wirtz, G.
JF - Proceedings : July 14 - 18, 2002, Orlando, Florida, USA ; [jointly with the 8th International Conference on Information Systems Analysis and Synthesis (ISAS 2002)] / organized by IIIS, International Institute of Informatics and Systemics. Ed. by Nagib Callaos
Y1 - 2002
SN - 9800781501
N1 - World Multiconference on Systemics, Cybernetics and Informatics ; (6, 2002, Orlando, Fla.) ; International Conference on Information Systems, Analysis and Synthesis ; (8, 2002, Orlando, Fla.) ; International Institute of Informatics and Systemics ; World Multiconference on Systemics, Cybernetics and Informatics ; (6 : ; 2002.07.14-18 : ; Orlando, Fla.) ; SCI 2002 ; (6 : ; 2002.07.14-18 : ; Orlando, Fla.) ; International Conference on Information Systems Analysis and Synthesis ; (8 : ; 2002.07.14-18 : ; Orlando, Fla.) ; ISAS 2002 ; (8 : ; 2002.07.14-18 : ; Orlando, Fla.)
PB - IIIS
CY - Orlando, Fla.
ER -
TY - JOUR
A1 - Hillen, Walter
A1 - Winterschlade, T.
A1 - Krone, J.
T1 - Erkennung lokaler Bildfehler in Röntgenbildverstärkern durch parallel arbeitende Bildrechner
JF - Parallele Datenverarbeitung : Entwurfsmethoden, Bildverarbeitung, Simulation ; Workshop der Arbeitsgemeinschaft "Parallelverarbeitung an Fachhochschulen in NRW" am 19.6.1998 in Bochum / Jörg Krone ... (Hrsg.)
Y1 - 1998
SN - 3-18-355310-4
N1 - Fortschritt-Berichte VDI : Reihe 10, Informatik, Kommunikationstechnik ; 553
SP - 88
EP - 94
PB - VDI-Verl.
CY - Düsseldorf
ER -
TY - JOUR
A1 - Hirschfeld, Julian A.
A1 - Lustfeld, Hans
A1 - Reißel, Martin
A1 - Steffen, Bernhard
T1 - A novel scheme for precise diagnostics and effective stabilization of currents in a fuel cell stack
JF - International Journal of Energy Research
N2 - A novel scheme for detecting inhomogeneous internal currents in a fuel cell stack is presented. In this paper the scheme is investigated for the case that the flow field plates consist of graphite. Then plates of high conductivity, e.g. aluminium between the flow field plates together with small slits in these plates have three effects: (a) Whenever a local inhomogeneity of the electric current occurs at a particular cell in the stack, this will induce a surface current close to that cell perpendicular to the averaged current. This current can be detected. (b) The plates of high conductivity completely prevent the inhomogeneities from spreading to neighbouring cells. (c) Even at the particular cell the inhomogeneity is suppressed as far as possible. Thus this scheme leads to much better diagnostic possibilities and at the same time reduces electric instabilities to an extent, where they probably become harmless. This scheme will first be explained for a simple model to clarify the idea. However, very precise three dimensional computations using realistic parameters are presented, corroborating the results of the simple model.
Y1 - 2010
U6 - https://doi.org/10.1002/er.1662
SN - 0363-907X
VL - 34
IS - 3
SP - 293
EP - 301
PB - Wiley
CY - London
ER -
TY - JOUR
A1 - Hirschfeld, Julian A.
A1 - Lustfeld, Hans
A1 - Reißel, Martin
A1 - Steffen, Bernhard
T1 - Tomographic diagnostics of current distributions in a fuel cell stack
JF - International Journal of Energy Research
N2 - A novel tomographic scheme for analysing the state of any single membrane electrode assembly (MEA) in a stack is suggested. Plates of very high conductivity placed between every fuel cell and slitted in an appropriate manner cause surface currents at well-defined locations of the stack. We show that knowing these surface currents, information about anomalies of the currents in a MEA can be obtained using the methods of tomography. The results are mathematically not unique. However, when assuming plausible defect structures, one can exclude improbable deficiencies by applying a special form of simulated annealing. We present numerical calculations of typical examples demonstrating that the essential defects of the MEA in any single cell of the stack can be detected and their extent can be determined.
Y1 - 2010
U6 - https://doi.org/10.1002/er.1634
SN - 0363-907X
VL - 34
IS - 3
SP - 284
EP - 292
PB - Wiley
CY - London
ER -
TY - JOUR
A1 - Honarvarfard, Elham
A1 - Gamella, Maria
A1 - Channaveerappa, Devika
A1 - Darie, Costel C.
A1 - Poghossian, Arshak
A1 - Schöning, Michael Josef
A1 - Katz, Evgeny
T1 - Electrochemically Stimulated Insulin Release from a Modified Graphene–functionalized Carbon Fiber Electrode
JF - Electroanalysis
N2 - A graphene-functionalized carbon fiber electrode was modified with adsorbed polyethylenimine to introduce amino functionalities and then with trigonelline and 4-carboxyphenylboronic acid covalently bound to the amino groups. The trigonelline species containing quarterized pyridine groups produced positive charge on the electrode surface regardless of the pH value, while the phenylboronic acid species were neutral below pH 8 and negatively charged above pH 9 (note that their pKa=8.4). The total charge on the monolayer-modified electrode was positive at the neutral pH and negative at pH > 9. Note that 4-carboxyphenylboronic acid was attached to the electrode surface in molar excess to trigonelline, thus allowing the negative charge to dominate on the electrode surface at basic pH. Negatively charged fluorescent dye-labeled insulin (insulin-FITC) was loaded on the modified electrode surface at pH 7.0 due to its electrostatic attraction to the positively charged interface. The local pH in close vicinity to the electrode surface was increased to ca. 9–10 due to consumption of H+ ions upon electrochemical reduction of oxygen proceeding at the potential of −1.0 V (vs. Ag/AgCl) applied on the modified electrode. The process resulted in recharging of the electrode surface to the negative value due to the formation of the negative charge on the phenylboronic acid groups, thus resulting in the electrostatic repulsion of insulin-FITC and stimulating its release from the electrode surface. The insulin release was characterized by fluorescence spectroscopy (using the FITC-labeled insulin), by electrochemical measurements on an iridium oxide, IrOx, electrode and by mass spectrometry. The graphene-functionalized carbon fiber electrode demonstrated significant advantages in the signal-stimulated insulin release comparing with the carbon fiber electrode without the graphene species.
Y1 - 2017
U6 - https://doi.org/10.1002/elan.201700095
SN - 1521-4109
VL - 29
IS - 6
SP - 1543
EP - 1553
PB - Wiley-VCH
CY - Weinheim
ER -
TY - JOUR
A1 - Honarvarfard, Elham
A1 - Gamella, Maria
A1 - Poghossian, Arshak
A1 - Schöning, Michael Josef
A1 - Katz, Evgeny
T1 - An enzyme-based reversible Controlled NOT (CNOT) logic gate operating on a semiconductor transducer
JF - Applied Materials Today
N2 - An enzyme-based biocatalytic system mimicking operation of a logically reversible Controlled NOT (CNOT) gate has been interfaced with semiconductor electronic transducers. Electrolyte–insulator–semiconductor (EIS) structures have been used to transduce chemical changes produced by the enzyme system to an electronically readable capacitive output signal using field-effect features of the EIS device. Two enzymes, urease and esterase, were immobilized on the insulating interface of EIS structure producing local pH changes performing XOR logic operation controlled by various combinations of the input signals represented by urea and ethyl butyrate. Another EIS transducer was functionalized with esterase only, thus performing Identity (ID) logic operation for the ethyl butyrate input. Both semiconductor devices assembled in parallel operated as a logically reversible CNOT gate. The present system, despite its simplicity, demonstrated for the first time logically reversible function of the enzyme system transduced electronically with the semiconductor devices. The biomolecular realization of a CNOT gate interfaced with semiconductors is promising for integration into complex biomolecular networks and future biosensor/biomedical applications.
KW - Electrolyte–insulator–semiconductor
KW - Capacitive field-effect
KW - CNOT
KW - XOR
KW - Enzyme logic gate
Y1 - 2017
U6 - https://doi.org/10.1016/j.apmt.2017.08.003
SN - 2352-9407
VL - 9
SP - 266
EP - 270
PB - Elsevier
CY - Amsterdam
ER -
TY - JOUR
A1 - Horbach, Andreas
A1 - Duong, Minh Tuan
A1 - Staat, Manfred
T1 - Modelling of compressible and orthotropic surgical mesh implants based on optical deformation measurement
JF - Journal of the mechanical behavior of biomedical materials
Y1 - 2017
U6 - https://doi.org/10.1016/j.jmbbm.2017.06.012
SN - 1751-6161
VL - 74
SP - 400
EP - 410
PB - Elsevier
CY - Amsterdam
ER -
TY - JOUR
A1 - Horbach, Andreas
A1 - Staat, Manfred
T1 - Optical strain measurement for the modeling of surgical meshes and their porosity
JF - Current Directions in Biomedical Engineering
N2 - The porosity of surgical meshes makes them flexible for large elastic deformation and establishes the healing conditions of good tissue in growth. The biomechanic modeling of orthotropic and compressible materials requires new materials models and simulstaneoaus fit of deformation in the load direction as well as trannsversely to to load. This nonlinear modeling can be achieved by an optical deformation measurement. At the same time the full field deformation measurement allows the dermination of the change of porosity with deformation. Also the socalled effective porosity, which has been defined to asses the tisssue interatcion with the mesh implants, can be determined from the global deformation of the surgical meshes.
Y1 - 2018
U6 - https://doi.org/10.1515/cdbme-2018-0045
SN - 2364-5504
VL - Band 4
IS - 1
SP - 181
EP - 184
PB - De Gruyter
CY - Berlin
ER -
TY - JOUR
A1 - Horbach, Andreas
A1 - Staat, Manfred
A1 - Perez-Viana, Daniel
A1 - Simmen, Hans-Peter
A1 - Neuhaus, Valentin
A1 - Pape, Hans-Christoph
A1 - Prescher, Andreas
A1 - Ciritsis, Bernhard
T1 - Biomechanical in vitro examination of a standardized low-volume tubular femoroplasty
JF - Clinical Biomechanics
N2 - Background
Osteoporosis is associated with the risk of fractures near the hip. Age and comorbidities increase the perioperative risk. Due to the ageing population, fracture of the proximal femur also proves to be a socio-economic problem. Preventive surgical measures have hardly been used so far.
Methods
10 pairs of human femora from fresh cadavers were divided into control and low-volume femoroplasty groups and subjected to a Hayes fall-loading fracture test. The results of the respective localization and classification of the fracture site, the Singh index determined by computed tomography (CT) examination and the parameters in terms of fracture force, work to fracture and stiffness were evaluated statistically and with the finite element method. In addition, a finite element parametric study with different position angles and variants of the tubular geometry of the femoroplasty was performed.
Findings
Compared to the control group, the work to fracture could be increased by 33.2%. The fracture force increased by 19.9%. The used technique and instrumentation proved to be standardized and reproducible with an average poly(methyl methacrylate) volume of 10.5 ml. The parametric study showed the best results for the selected angle and geometry.
Interpretation
The cadaver studies demonstrated the biomechanical efficacy of the low-volume tubular femoroplasty. The numerical calculations confirmed the optimal choice of positioning as well as the inner and outer diameter of the tube in this setting. The standardized minimally invasive technique with the instruments developed for it could be used in further comparative studies to confirm the measured biomechanical results.
Y1 - 2020
U6 - https://doi.org/10.1016/j.clinbiomech.2020.105104
VL - 80
IS - Art. 105104
PB - Elsevier
CY - Amsterdam
ER -
TY - JOUR
A1 - Horstmann, Marie-Therese
A1 - Bialonski, Stephan
A1 - Noenning, Nina
A1 - Mai, Heinke
A1 - Prusseit, Jens
A1 - Wellmer, Jörg
A1 - Hinrichs, Hermann
A1 - Lehnertz, Klaus
T1 - State dependent properties of epileptic brain networks: Comparative graph–theoretical analyses of simultaneously recorded EEG and MEG
JF - Clinical Neurophysiology
N2 - Objective
To investigate whether functional brain networks of epilepsy patients treated with antiepileptic medication differ from networks of healthy controls even during the seizure-free interval.
Methods
We applied different rules to construct binary and weighted networks from EEG and MEG data recorded under a resting-state eyes-open and eyes-closed condition from 21 epilepsy patients and 23 healthy controls. The average shortest path length and the clustering coefficient served as global statistical network characteristics.
Results
Independent on the behavioral condition, epileptic brains exhibited a more regular functional network structure. Similarly, the eyes-closed condition was characterized by a more regular functional network structure in both groups. The amount of network reorganization due to behavioral state changes was similar in both groups. Consistent findings could be achieved for networks derived from EEG but hardly from MEG recordings, and network construction rules had a rather strong impact on our findings.
Conclusions
Despite the locality of the investigated processes epileptic brain networks differ in their global characteristics from non-epileptic brain networks. Further methodological developments are necessary to improve the characterization of disturbed and normal functional networks.
Significance
An increased regularity and a diminished modulation capability appear characteristic of epileptic brain networks.
Y1 - 2010
U6 - https://doi.org/10.1016/j.clinph.2009.10.013
SN - 1388-2457
VL - 121
IS - 2
SP - 172
EP - 185
PB - Elsevier
CY - Amsterdam
ER -
TY - JOUR
A1 - Huck, Christina
A1 - Jolly, Christina
A1 - Wagner, Patrick
A1 - Poghossian, Arshak
A1 - Schöning, Michael Josef
T1 - One-chip integrated dual amperometric/field-effect sensor for the detection of dissolved hydrogen
JF - Procedia Engineering. 25 (2011)
Y1 - 2011
SN - 1877-7058
N1 - EurosensorsXXV ; Proc. Eurosensors XXV, September 4-7, 2011, Athens, Greece
SP - 1161
EP - 1164
PB - Elsevier
CY - Amsterdam
ER -
TY - JOUR
A1 - Huck, Christina
A1 - Poghossian, Arshak
A1 - Bäcker, Matthias
A1 - Chaudhuri, S.
A1 - Zander, W.
A1 - Schubert, J.
A1 - Begoyan, V. K.
A1 - Buniatyan, V. V.
A1 - Wagner, P.
A1 - Schöning, Michael Josef
T1 - Capacitively coupled electrolyte-conductivity sensor based on high-k material of barium strontium titanate
JF - Sensors and actuators. B: Chemical
Y1 - 2014
U6 - https://doi.org/10.1016/j.snb.2014.02.103
SN - 1873-3077 (E-Journal); 0925-4005 (Print)
IS - 198
SP - 102
EP - 109
PB - Elsevier
CY - Amsterdam
ER -
TY - JOUR
A1 - Huck, Christina
A1 - Poghossian, Arshak
A1 - Bäcker, Matthias
A1 - Reisert, Steffen
A1 - Kramer, Friederike
A1 - Begoyan, Vardges K.
A1 - Buniatyan, Vahe V.
A1 - Schöning, Michael Josef
T1 - Multi-parameter sensing using high-k oxide of barium strontium titanate
JF - Physica status solidi (a)
N2 - High-k perovskite oxide of barium strontium titanate (BST) represents a very attractive multi-functional transducer material for the development of (bio-)chemical sensors. In this work, a Si-based sensor chip containing Pt interdigitated electrodes covered with a thin BST layer (485 nm) has been developed for multi-parameter chemical sensing. The chip has been applied for the contactless measurement of the electrolyte conductivity, the detection of adsorbed charged macromolecules (positively charged polyelectrolytes of polyethylenimine) and the concentration of hydrogen peroxide (H2O2) vapor. The experimental results of functional testing of individual sensors are presented. The mechanism of the BST sensitivity to charged polyelectrolytes and H2O2 vapor has been proposed and discussed.
Y1 - 2015
U6 - https://doi.org/10.1002/pssa.201431911
SN - 1862-6319
VL - 212
IS - 6
SP - 1259
PB - Wiley
CY - Weinheim
ER -
TY - JOUR
A1 - Huck, Christina
A1 - Poghossian, Arshak
A1 - Bäcker, Matthias
A1 - Reisert, Steffen
A1 - Schubert, J.
A1 - Zander, W.
A1 - Begoyan, V. K.
A1 - Buniatyan, V. V.
A1 - Schöning, Michael Josef
T1 - Chemical sensors based on a high-k perovskite oxide of barium strontium titanate
JF - Procedia Engineering
N2 - High-k perovskite oxide of barium strontium titanate (BST) represents a very attractive multi-functional transducer material for the development of (bio-)chemical sensors for liquids. In this work, BST films have been applied as a sensitive transducer material for a label-free detection of adsorbed charged macromolecules (positively charged polyelectrolytes) and concentration of hydrogen peroxide vapor as well as protection insulator layer for a contactless electrolyte-conductivity sensor. The experimental results of characterization of individual sensors are presented. Special emphasis is devoted towards the development of a capacitively-coupled contactless electrolyte-conductivity sensor.
KW - barium strontium titanate
KW - high-k material
KW - contactless conductivity sensor
KW - multi-functional material
KW - hydrogen peroxide
Y1 - 2014
U6 - https://doi.org/10.1016/j.proeng.2014.11.258
SN - 1877-7058
N1 - EUROSENSORS 2014 ; European Conference on Solid-State Transducers <28, 2014>
VL - 87
SP - 28
EP - 31
PB - Elsevier
CY - Amsterdam
ER -
TY - JOUR
A1 - Huck, Christina
A1 - Poghossian, Arshak
A1 - Kerroumi, Iman
A1 - Schusser, Sebastian
A1 - Bäcker, Matthias
A1 - Zander, Willi
A1 - Schubert, Jürgen
A1 - Buniatyan, Vahe V.
A1 - Martirosyan, Norayr W.
A1 - Wagner, Patrick
A1 - Schöning, Michael Josef
T1 - Multiparameter sensor chip with Barium Strontium Titanate as multipurpose material
JF - Electroanalysis
N2 - It is well known that biochemical and biotechnological processes are strongly dependent and affected by a variety of physico-chemical parameters such as pH value, temperature, pressure and electrolyte conductivity. Therefore, these quantities have to be monitored or controlled in order to guarantee a stable process operation, optimization and high yield. In this work, a sensor chip for the multiparameter detection of three physico-chemical parameters such as electrolyte conductivity, pH and temperature is realized using barium strontium titanate (BST) as multipurpose material. The chip integrates a capacitively coupled four-electrode electrolyte-conductivity sensor, a capacitive field-effect pH sensor and a thin-film Pt-temperature sensor. Due to the multifunctional properties of BST, it is utilized as final outermost coating layer of the processed sensor chip and serves as passivation and protection layer as well as pH-sensitive transducer material at the same time. The results of testing of the individual sensors of the developed multiparameter sensor chip are presented. In addition, a quasi-simultaneous multiparameter characterization of the sensor chip in buffer solutions with different pH value and electrolyte conductivity is performed. To study the sensor behavior and the suitability of BST as multifunctional material under harsh environmental conditions, the sensor chip was exemplarily tested in a biogas digestate.
Y1 - 2014
U6 - https://doi.org/10.1002/elan.201400076
SN - 1521-4109 (E-Journal); 1040-0397 (Print)
VL - 26
IS - 5
SP - 980
EP - 987
PB - Wiley-VCH
CY - Weinheim
ER -
TY - JOUR
A1 - Huck, Christina
A1 - Poghossian, Arshak
A1 - Wagner, Patrick
A1 - Schöning, Michael Josef
T1 - Combined amperometric/field-effect sensor for the detection of dissolved hydrogen
JF - Sensors and actuators B: Chemical
N2 - Real-time and reliable monitoring of the biogas process is crucial for a stable and efficient operation of biogas production in order to avoid digester breakdowns. The concentration of dissolved hydrogen (H₂) represents one of the key parameters for biogas process control. In this work, a one-chip integrated combined amperometric/field-effect sensor for monitoring the dissolved H₂ concentration has been developed for biogas applications. The combination of two different transducer principles might allow a more accurate and reliable measurement of dissolved H₂ as an early warning indicator of digester failures. The feasibility of the approach has been demonstrated by simultaneous amperometric/field-effect measurements of dissolved H₂ concentrations in electrolyte solutions. Both, the amperometric and the field-effect transducer show a linear response behaviour in the H₂ concentration range from 0.1 to 3% (v/v) with a slope of 198.4 ± 13.7 nA/% (v/v) and 14.9 ± 0.5 mV/% (v/v), respectively.
Y1 - 2012
U6 - https://doi.org/10.1016/j.snb.2012.10.050
SN - 0925-4005
N1 - Part of special issue "Selected Papers from the 14th International Meeting on Chemical Sensors"
VL - 187
SP - 168
EP - 173
PB - Elsevier
CY - Amsterdam
ER -
TY - JOUR
A1 - Huck, Christina
A1 - Schiffels, Johannes
A1 - Herrera, Cony N.
A1 - Schelden, Maximilian
A1 - Selmer, Thorsten
A1 - Poghossian, Arshak
A1 - Baumann, Marcus
A1 - Wagner, Patrick
A1 - Schöning, Michael Josef
T1 - Metabolic responses of Escherichia coli upon glucose pulses captured by a capacitive field-effect sensor
JF - Physica Status Solidi (A)
N2 - Living cells are complex biological systems transforming metabolites taken up from the surrounding medium. Monitoring the responses of such cells to certain substrate concentrations is a challenging task and offers possibilities to gain insight into the vitality of a community influenced by the growth environment. Cell-based sensors represent a promising platform for monitoring the metabolic activity and thus, the “welfare” of relevant organisms. In the present study, metabolic responses of the model bacterium Escherichia coli in suspension, layered onto a capacitive field-effect structure, were examined to pulses of glucose in the concentration range between 0.05 and 2 mM. It was found that acidification of the surrounding medium takes place immediately after glucose addition and follows Michaelis–Menten kinetic behavior as a function of the glucose concentration. In future, the presented setup can, therefore, be used to study substrate specificities on the enzymatic level and may as well be used to perform investigations of more complex metabolic responses. Conclusions and perspectives highlighting this system are discussed.
Y1 - 2013
U6 - https://doi.org/10.1002/pssa.201200900
SN - 0031-8965
VL - 210
IS - 5
SP - 926
EP - 931
PB - Wiley-VCH
CY - Weinheim
ER -