TY - JOUR A1 - Schwertner, Eberhard A1 - Berndt, Heinz A1 - Gielen, Hans-Günter A1 - Zahn, Helmut T1 - Peptide 96 : Synthese einiger [2-(p-Biphenylyl)isopropyloxycarbonyl]-Aminosäurederivate JF - Justus Liebigs Annalen der Chemie N2 - Die Darstellung der N-[2-(p-Biphenylyl)isopropyloxycarbonyl]-Derivate (Bpoc-Derivate) des Cysteins unter Verwendung der Thiolschutzgruppen Tetrahydropyranyl (Thp) für 1, Diphenylmethyl (Dpm) für 2, Trityl (Trt) für 3 und S-tert.-Butyl (SBut) für 4 sowie die Synthese von aktivierten Estern der Bpoc-Derivate des Glycins (5), Isoleucins (6) und Prolins (7) werden beschrieben. An einem Beispiel wird die Möglichkeit aufgezeigt, die Bpoc-Gruppe über das Bpoc-Azid nachträglich in den Peptidverband einzuführen. Y1 - 1975 U6 - https://doi.org/10.1002/jlac.197519750318 SN - 1099-0690 VL - 75 IS - 3 SP - 581 EP - 585 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Fabo, Sabine ED - Mohr, Klaus T1 - Pepräsentatives Dösen JF - Idiopendent Lyfestile (Boxhorn ; 27) Y1 - 2013 SN - 1864-2535 SP - 134 EP - 139 PB - FH CY - Aachen ER - TY - JOUR A1 - Abouzar, Maryam H. A1 - Poghossian, Arshak A1 - Razavi, Arash A1 - Besmehn, Astrid A1 - Bijnens, Nathalie A1 - Williams, Oliver A. A1 - Haenen, Ken A1 - Wagner, Patrick A1 - Schöning, Michael Josef T1 - Penicillin detection with nanocrystalline-diamond field-effect sensor JF - physica status solidi (a). 205 (2008), H. 9 Y1 - 2008 SN - 1862-6319 N1 - Special Issue: Hasselt Diamond Workshop 2008 - SBDD XIII SP - 2141 EP - 2145 ER - TY - JOUR A1 - Koch, Claudia A1 - Poghossian, Arshak A1 - Schöning, Michael Josef A1 - Wege, Christian T1 - Penicillin Detection by Tobacco Mosaic Virus-Assisted Colorimetric Biosensors JF - Nanotheranostics N2 - The presentation of enzymes on viral scaffolds has beneficial effects such as an increased enzyme loading and a prolonged reusability in comparison to conventional immobilization platforms. Here, we used modified tobacco mosaic virus (TMV) nanorods as enzyme carriers in penicillin G detection for the first time. Penicillinase enzymes were conjugated with streptavidin and coupled to TMV rods by use of a bifunctional biotin-linker. Penicillinase-decorated TMV particles were characterized extensively in halochromic dye-based biosensing. Acidometric analyte detection was performed with bromcresol purple as pH indicator and spectrophotometry. The TMV-assisted sensors exhibited increased enzyme loading and strongly improved reusability, and higher analysis rates compared to layouts without viral adapters. They extended the half-life of the sensors from 4 - 6 days to 5 weeks and thus allowed an at least 8-fold longer use of the sensors. Using a commercial budget-priced penicillinase preparation, a detection limit of 100 µM penicillin was obtained. Initial experiments also indicate that the system may be transferred to label-free detection layouts. Y1 - 2018 U6 - https://doi.org/10.7150/ntno.22114 SN - 2206-7418 VL - 2 IS - 2 SP - 184 EP - 196 PB - Ivyspring CY - Sydney ER - TY - JOUR A1 - Poghossian, Arshak A1 - Thust, M. A1 - Schroth, P. A1 - Steffen, A. A1 - Lüth, H. A1 - Schöning, Michael Josef T1 - Penicillin detection by means of silicon-based field-effect structures JF - Sensors and Materials. 13 (2001), H. 4 Y1 - 2001 SN - 0392-2510 SP - 207 EP - 223 ER - TY - JOUR A1 - Poghossian, Arshak A1 - Yoshinobu, T. A1 - Simonis, A. A1 - Ecken, H. A1 - Lüth, H. A1 - Schöning, Michael Josef T1 - Penicillin detection by means of field-effect based sensors: EnFET, capacitive EIS sensor or LAPS? JF - Proceedings : Copenhagen, Denmark, 27 - 30 August 2000 / [ed.: R. de Reus ...] Y1 - 2000 SN - 87-89935-50-0 N1 - Eurosensors ; (14, 2000, København) ; Eurosensors ; (14 : ; 2000.08.27-30 : ; Copenhagen) ; European Conference on Solid-State Transducers ; (14 : ; 2000.08.27-30 : ; Copenhagen) SP - 27 EP - 30 PB - MIC, Mikroelektronik Centret CY - Lyngby, Denmark ER - TY - JOUR A1 - Poghossian, Arshak A1 - Yoshinobu, Tatsuo A1 - Simonis, A. A1 - Ecken, H. A1 - Lüth, Hans A1 - Schöning, Michael Josef T1 - Penicillin detection by means of field-effect based sensors: EnFET, capacitive EIS sensor or LAPS? JF - Sensors and Actuators B. 78 (2001), H. 1-3 Y1 - 2001 SN - 0925-4005 SP - 237 EP - 242 ER - TY - JOUR A1 - Siqueira, José R. Jr. A1 - Abouzar, Maryam H. A1 - Poghossian, Arshak A1 - Zucolotto, Valtencir A1 - Oliveira, Osvaldo N. Jr. A1 - Schöning, Michael Josef T1 - Penicillin biosensor based on a capacitive field-effect structure functionalized with a dendrimer/carbon nanotube multilayer JF - Biosensors and Bioelectronics. 25 (2009), H. 2 Y1 - 2009 SN - 0956-5663 SP - 497 EP - 501 ER - TY - JOUR A1 - Mühl, Thomas A1 - Schwarz, Michael T1 - Pegel- und Dämpfungsmessung an Wellenlängenmultiplex-Systemen und -Komponenten JF - Nachrichtentechnische Zeitschrift. 46 (1993), H. 1 Y1 - 1993 SN - 0027-707X SP - 36 EP - 38 ER - TY - JOUR A1 - Förster, Arnold A1 - Schmidt, T. A1 - Tewordt, M. A1 - Haug, R. J. T1 - Peak-to-valley ratio of small resonant-tunneling diodes with various barrier-thickness asymmetries / T. Schmidt ; M. Tewordt ; R. J. Haug ... A. Förster ... JF - Applied physics letters. 68 (1996), H. 6 Y1 - 1996 SN - 0003-6951 N1 - ISSN der E-Ausg.: 1077-3118 SP - 838 EP - 840 ER - TY - JOUR A1 - Hagemann, Hans-Jürgen A1 - Geittner, P. T1 - PCVD hybrid technology for single mode fibres. Hagemann, H. J.; Geittner, P. JF - Proceedings : papers presented at: the 8th Annual European Fibre Optic Communications and Local Area Networks Exposition Y1 - 1990 N1 - EFOC LAN <8, 1990, München> SP - 67 EP - 72 ER - TY - JOUR A1 - Hagemann, Hans-Jürgen A1 - Geittner, P. A1 - Warnier, J. A1 - Wilson, H. T1 - PCVD at high deposition rates. Geittner, P.; Hagemann, H. J.; Warnier, J.; Wilson, H. JF - Journal of Lightwave Technology (J-LT) / Institute of Electrical and Electronics Engineers (IEEE). 4 (1986), H. 7 Y1 - 1986 SN - 0733-8724 SP - 818 EP - 822 ER - TY - JOUR A1 - Weber, Hans-Joachim A1 - Mo, Xiumei A1 - Ramakrishna, S. T1 - PCL-PGLA composite tubular scaffold preparation and biocompatibility investigation / X. Mo, H.-J. Weber, S. Ramakrishna JF - The International journal of artificial organs. 29 (2006), H. 8 Y1 - 2006 SP - 790 EP - 799 PB - - ER - TY - JOUR A1 - Starke, Günther T1 - PC-gestützte Programmierung einer Orbitalschweißanlage JF - Qualitätsorientierte Schweißtechnik als Wettbewerbsfaktor, DVS-Berichte. 196 (1999) Y1 - 1999 SN - 0418-9639 N1 - Report SP - 65 EP - 68 ER - TY - JOUR A1 - Valero, Daniel A1 - Schalko, Isabella A1 - Friedrich, Heide A1 - Abad, Jorge D. A1 - Bung, Daniel Bernhard A1 - Donchyts, Gennadii A1 - Felder, Stefan A1 - Ferreira, Rui M. L. A1 - Hohermuth, Benjamin A1 - Kramer, Matthias A1 - Li, Danxun A1 - Mendes, Luis A1 - Moreno-Rodenas, Antonio A1 - Nones, Michael A1 - Paron, Paolo A1 - Ruiz-Villanueva, Virginia A1 - Wang, Ruo-Qian A1 - Franca, Mario J. T1 - Pathways towards democratization of hydro-environment observations and data JF - Iahr White Paper Series Y1 - 2021 IS - 1 SP - 1 EP - 9 PB - International Association for Hydro-Environment Engineering and Research (IAHR) ER - TY - JOUR A1 - Spietz, Peter A1 - Spröwitz, Tom A1 - Seefeldt, Patric A1 - Grundmann, Jan Thimo A1 - Jahnke, Rico A1 - Mikschl, Tobias A1 - Mikulz, Eugen A1 - Montenegro, Sergio A1 - Reershemius, Siebo A1 - Renger, Thomas A1 - Ruffer, Michael A1 - Sasaki, Kaname A1 - Sznajder, Maciej A1 - Tóth, Norbert A1 - Ceriotti, Matteo A1 - Dachwald, Bernd A1 - Macdonald, Malcolm A1 - McInnes, Colin A1 - Seboldt, Wolfgang A1 - Quantius, Dominik A1 - Bauer, Waldemar A1 - Wiedemann, Carsten A1 - Grimm, Christian D. A1 - Hercik, David A1 - Ho, Tra-Mi A1 - Lange, Caroline A1 - Schmitz, Nicole T1 - Paths not taken – The Gossamer roadmap’s other options JF - Advances in Space Research KW - Solar sail KW - Small spacecraft KW - DLR-ESTEC GOSSAMER roadmap for solar sailing KW - GOSSAMER-1 Y1 - 2021 U6 - https://doi.org/10.1016/j.asr.2021.01.044 SN - 0273-1177 VL - 67 IS - 9 SP - 2912 EP - 2956 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Kohler, Annette A1 - Kirschner-Hermanns, Ruth A1 - Staat, Manfred A1 - Brehmer, Bernhard T1 - Pathogenese, funktionelle und anatomische Aspekte der weiblichen Belastungsinkontinenz T1 - Female stress incontinence: aspects of pathogenesis and functional anatomy JF - Aktuelle Urologie N2 - Der vorliegende Artikel fokussiert sich auf die weibliche Belastungsinkontinenz als Insuffizienz der Speicherfunktion der Blase, auch wenn im klinischen Alltag die Harninkontinenz der Frau häufig verschiedene Ursachen hat und insbesondere eine Belastungsinkontinenz im Alter und bei neurologischer Komorbidität nur selten isoliert vorkommt. Das kleine Becken der Frau ist sowohl als Funktions- als auch als strukturelle Einheit zu betrachten. Dabei unterliegen bei der Frau Blase, Harnröhre, Gebärmutter und Enddarm sowie die muskulären und ligamentösen Strukturen des kleinen Beckens durch Fertilitätsphase, mögliche Schwangerschaften, Geburten und Menopausen-Phase, über das „normale Altern“ hinaus, gravierenden Veränderungen. This article focuses on female stress incontinence in the form of pelvic floor dysfunction and urethral sphincter deficiency, although isolated stress incontinence accounts for less than half of all incontinence cases. Especially in women of old age and those with neurological comorbidities, the causes of incontinence are mostly multifactorial. Also it has to be considered that the female bladder, urethra, uterus and rectum as well as the muscular and ligamentous structures of the female pelvis minor are affected by phases of fertility, possible pregnancies, births and menopause in addition to the normal ageing process. Y1 - 2018 U6 - https://doi.org/10.1055/s-0043-120616 SN - 1438-8820 VL - 49 IS - 1 SP - 47 EP - 51 PB - Thieme CY - Stuttgart ER - TY - JOUR A1 - Mottaghy, Darius A1 - Schwamborn, G. A1 - Rath, V. T1 - Past climate changes and permafrost depth at the Lake El'gygytgyn site: implications from data and thermal modeling JF - Climate of the Past Y1 - 2013 U6 - https://doi.org/10.5194/cp-9-119-2013 SN - 1814-9332 VL - 9 IS - 1 SP - 119 EP - 133 PB - Copernicus CY - Katlenburg-Lindau ER - TY - JOUR A1 - Reger, V. A1 - Döring, Bernd A1 - Kuhnhenne, M. T1 - Passive und aktive Maßnahmen zur Flächenkühlung im Stahl(leicht)bau JF - Bauingenieur N2 - Mit steigenden Dämmstandards und höheren Komfortanforderungen der Nutzer gerät die Problematik der sommerlichen Überhitzung zunehmend in den Fokus. Um die Überhitzung möglichst gering zu halten, sind Maßnahmen und Lösungen zu entwickeln, die den potenziellen Kühlbedarf eines Gebäudes vermeiden sowie reduzieren. Im Rahmen des europäischen Forschungsprojektes BATIMASS wurden Techniken untersucht, die die sommerliche Raumtemperatur ohne zusätzliche Kühlung (passiv) oder aber mit energieeffizienter wasserbasierter Flächenkühlung (aktiv) reduzieren und die besonders für Gebäude in Stahl(leicht)bauweise geeignet sind. Dafür wurde die Methodik der thermisch äquivalenten Decke weiterentwickelt, um das thermische Verhalten von Profilblechdecken in Gebäuden für beide Lösungsansätze analysieren zu können. Darüber hinaus wurde der Einsatz von Phasenwechselmaterial (PCM) zur Steigerung der Speicherfähigkeit von leichten Decken mit besonders geringer thermischer Masse in Simulationen sowie im Labor untersucht und bewertet. Y1 - 2016 U6 - https://doi.org/10.37544/0005-6650-2016-07-08-63 SN - 0005-6650 N1 - gedruckt in der Bereichsbibliothek Bayernallee unter der Signatur 13 Z 049 VL - 91 IS - Jul/Aug SP - 309 EP - 316 PB - VDI Fachmedien CY - Düsseldorf ER - TY - JOUR A1 - Faßbender, F. A1 - Schmitt, G. A1 - Schöning, Michael Josef A1 - Lüth, H. A1 - Buß, G. A1 - Schultze, J. W. T1 - Passivation and corrosion of microsensor devices exemplified at microelectrode arrays JF - Proceedings : The Hague, The Netherlands, September 12 - 15, 1999 / [ed. by M. Bartek]. Vol 1. Y1 - 1999 SN - 90-76699-02-X N1 - Eurosensors ; (13, 1999, 's-Gravenhage) ; Eurosensors ; (13 : ; 1999.09.12-15 : ; The Hague) ; European Conference on Solid-State Transducers ; (13 : ; 1999.09.12-15 : ; The Hague) SP - 953 EP - 956 CY - The Hague, The Netherlands ER - TY - JOUR A1 - Schmitt, G. A1 - Schultze, J.-W. A1 - Faßbender, F. A1 - Buß, G. A1 - Lüth, H. A1 - Schöning, Michael Josef T1 - Passivation and corrosion of microelectrode arrays JF - Electrochimica Acta. 44 (1999), H. 21-22 Y1 - 1999 SN - 0013-4686 SP - 3865 EP - 3883 ER - TY - JOUR A1 - Schmitt, G. A1 - Faßbender, F. A1 - Lüth, H. A1 - Schöning, Michael Josef A1 - Schultze, J. W. A1 - Buß, G. T1 - Passivation and corrosion of microelectrode arrays JF - Materials and Corrosion. 51 (2000), H. 1 Y1 - 2000 SN - 0947-5117 SP - 20 EP - 25 ER - TY - JOUR A1 - Grap, Rolf Dietmar T1 - Partizipative Organisationsentwicklung : Praktische Modelle in Deutschland JF - Personal. 45 (1993), H. 8 Y1 - 1993 SP - 348 EP - 352 ER - TY - JOUR A1 - Helsper, Christoph T1 - Partikelmesstechnik JF - Reinraumtechnik , Hrsg.: Gail, Lothar Y1 - 2002 SN - 3-540-66885-3 SP - 57 EP - 82 PB - Springer CY - Berlin [u.a.] ER - TY - JOUR A1 - Kotter, Michael A1 - Li, D. X. A1 - Riekert, Lothar T1 - Partielle Oxidation von o-Xylol zu Phthalsäureanhydrid in einem strukturierten Festbettreaktor JF - Katalyse : katalytische Abgasreinigung, Zeolithe, homogene Katalyse, selektive Reaktionen, Herstellung und Charakterisierung, Ionenleiter, Elektrokatalyse, SLPC-Katalysatoren, Suspensionsphase ; Vorträge von der DECHEMA-Jahrestagung 1990, 31. Mai und 1. Juni 1990 / hrsg. von H. Kral. - (Deutsche Gesellschaft für Chemisches Apparatewesen, Chemische Technik und Biotechnologie: DECHEMA-Monographien ; 122) Y1 - 1991 SN - 3-527-10216-7 SP - 93 EP - 123 PB - VCH CY - Weinheim ER - TY - JOUR A1 - Kotter, Michael A1 - Xing Li, Dong T1 - Partielle Oxidation von o-Xylol zu Phthalsäreanhydrid an V/Ti-Schalenkatalysatoren : [Synopsis 1898] JF - Chemie - Ingenieur - Technik. 62 (1990), H. 11 Y1 - 1990 SN - 0009-286X N1 - ISSN der E-Ausg.: 1522-2640 ; Das vollständige Manuskript dieser Arbeit umfasst 33 Seiten. Es ist [lt. Verl.] als Fotokopie oder Mikrofiche MS 1898/90 erhältlich. SP - 950 EP - 951 ER - TY - JOUR A1 - Kallweit, Stephan A1 - Dues, M. A1 - Siekmann, H. T1 - Particle-Image-Velocimetry (PIV) in rotierenden Maschinen / Dues, M. ; Kallweit, S. ; Siekmann, H. JF - Lasermethoden in der Strömungsmesstechnik, 3. Fachtagung der Deutschen Gesellschaft für Laser-Anemometrie (GALA), Bremen, DE, 5.-7. Sep, 1994 Y1 - 1994 SN - 3-8265-0162-4 N1 - Lasermethoden in der Strömungsmesstechnik, Fachtagung, 3 SP - 19.1 EP - 19-5 PB - Shaker CY - Aachen ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Gono, Y. A1 - Lieder, R. M. A1 - Neskakis, A. T1 - Particle-hole symmetry observed in the angular distributions of γ-rays in ¹⁸⁹,¹⁹¹,¹⁹³ Au JF - Annual report 1977 / Institut für Kernphysik Kernforschungsanlage Jülich Y1 - 1978 N1 - Spezielle Berichte der Kernforschungsanlage Jülich ; 15 SP - 45 EP - 46 PB - Verlag des Forschungszentrums Jülich CY - Jülich ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Gono, Y. A1 - Lieder, R. M. A1 - Neskakis, A. T1 - Particle-hole symmetry observed in the angular distributions of γ-rays in ¹⁸⁹,¹⁹¹,¹⁹³ Au JF - Physics letters / B. 70 (1977), H. 2 Y1 - 1977 SN - 0031-9163 SP - 159 EP - 162 ER - TY - JOUR A1 - Helsper, Christoph A1 - Fißan, H. J. A1 - Muggli, J. A1 - Scheidweiler, A. T1 - Particle Number Distributions of Aerosols from Test Fires JF - Journal of Aerosol Science. 11 (1980), H. 5-6 Y1 - 1980 SN - 0021-8502 SP - 439 EP - 446 ER - TY - JOUR A1 - Havermann, Marc A1 - Haertig, J. A1 - Rey, C. A1 - George, A. T1 - Particle image velocimetry in mach 3.5 and 4.5 shock-tunnel flows / Haertig, J. ; Havermann, M. ; Rey, C. ; George, A. JF - AIAA journal. 40 (2002), H. 6 Y1 - 2002 SN - 0001-1452 N1 - Printausgabe in der Bereichsbibliothek Eupener Str. Signatur: 23 Z 701 SP - 1056 EP - 1060 PB - - ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Beuscher, H. A1 - Gono, Y. A1 - Lieder, R. M. T1 - Particle and collective properties of high spin states in heavy nuclei near z=82 JF - Frühjahrstagung ... des Fachausschusses Kernphysik und Hochenergiephysik der DPG (Sektion A: Kernphysik) / Deutsche Physikalische Gesellschaft (1977) Y1 - 1977 SP - 985 ER - TY - JOUR A1 - Kotter, Michael A1 - Li, D. X. A1 - Riekert, Lothar T1 - Partial oxidation of o-xylene to phthalic anhydride in a structured fixed bed containing a sequence of catalysts JF - New developments in selective oxidation : proceedings of an international symposium ; Rimini, Italy, Sept. 18 - 22, 1989 / eds.: G. Centi ... - (Studies in surface science and catalysis ; 55) Y1 - 1990 SN - 0-444-88694-X SP - 267 EP - 274 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Baier, Reinhold A1 - Hebel, Christoph T1 - Parkraumbewirtschaftung und Modal-Split - die relativierte Stellschraube JF - Strassenverkehrstechnik . 45 (2001), H. 4 Y1 - 2001 SN - 0039-2219 N1 - Printausgabe in der Bereichsbibliothek Bayernallee unter der Signatur 13 Z 208-2001 SP - 165 EP - 167 ER - TY - JOUR A1 - Fabo, Sabine T1 - Parasitäre Strategien : Einführung JF - Kunstforum International Y1 - 2007 SN - 0177-3674 VL - 2007 IS - 185 SP - 46 EP - 59 ER - TY - JOUR A1 - Fabo, Sabine T1 - Parasitäre Strategien : die Kunst der (un)freundlichen Übernahme JF - Kunstforum International Y1 - 2007 SN - 0177-3674 VL - 2007 IS - 185 SP - 138 EP - 163 ER - TY - JOUR A1 - Matcha, Heike ED - Martens, B. T1 - Parametrized Systems: Conceiving of Buildings as Assemblies of Varied Parts JF - Real Time - Proceedings of the 33rd eCAADe Conference - Volume 2, Vienna University of Technology, Vienna, Austria, 16-18 September 2015 Y1 - 2015 SP - 143 EP - 148 ER - TY - JOUR A1 - Funke, Harald A1 - Recker, E. A1 - Bosschaerts, W. A1 - Boonen, Q. A1 - Börner, Sebastian T1 - Parametrical study of the „Micromix“ hydrogen combustion principle JF - 10th International Symposium on Experimental and Computational Aerothermodynamics of Internal Flows, ISAIF10-049, Brussels, Belgium, 4-7 July 2011 Y1 - 2011 ER - TY - JOUR A1 - Dachwald, Bernd A1 - Mengali, Giovanni A1 - Quarta, Alessandrao A. A1 - Macdonald, Malcolm T1 - Parametric Model and Optimal Control of Solar Sails with Optical Degradation JF - Journal of guidance, control, and dynamics. 29 (2006), H. 5 Y1 - 2006 SN - 0162-3192 N1 - 2. ISSN: 0731-5090 SP - 1170 EP - 1178 ER - TY - JOUR A1 - Taddei, Francesca A1 - Butenweg, Christoph A1 - Klinkel, S. T1 - Parametric investigation of the soil-structure interaction effects on the dynamic behaviour of a shallow foundation supported wind turbine considering a layered soil JF - Wind energy : an international journal for progress and applications in wind power conversion technology Y1 - 2015 U6 - https://doi.org/10.1002/we.1703 SN - 1099-1824 (E-Journal); 1095-4244 (Print) VL - Volume 18 IS - Issue 3 SP - 399 EP - 417 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Sponagel, Stefan A1 - Baroud, G. A1 - Steffen, T. A1 - Wu, J. T1 - Parameter identification for cement infiltration of osteoporotic bone JF - Poromechanics II : Proceedings of the Second Biot Conference on Poromechanics Grenoble, France 26 - 28 August 2002 / ed. by J.-L. Auriault ... Y1 - 2002 SN - 90-5809-394-8 SP - 55 EP - 58 PB - Balkema CY - Lisse [u.a.] ER - TY - JOUR A1 - Fabo, Sabine T1 - Parallelprozess Literatur : Joseph Beuys’ Zeichnungen zum Ulysses JF - Kunstforum international Y1 - 1998 SN - 0177-3674 VL - 1998 IS - 140 SP - 84 EP - 95 ER - TY - JOUR A1 - Tippkötter, Nils A1 - Roikaew, Wipa A1 - Ulber, Roland A1 - Hoffmann, Alexander A1 - Denzler, Hans-Jörg A1 - Buchholz, Heinrich T1 - Paracoccus denitrificans for the effluent recycling during continuous denitrification of liquid food JF - Biotechnology Progress N2 - Nitrate is an undesirable component of several foods. A typical case of contamination with high nitrate contents is whey concentrate, containing nitrate in concentrations up to 25 l. The microbiological removal of nitrate by Paracoccus denitrificans under formation of harmless nitrogen in combination with a cell retention reactor is described here. Focus lies on the resource-conserving design of a microbal denitrification process. Two methods are compared. The application of polyvinyl alcohol-immobilized cells, which can be applied several times in whey feed, is compared with the implementation of a two step denitrification system. First, the whey concentrate's nitrate is removed by ion exchange and subsequently the eluent regenerated by microorganisms under their retention by crossflow filtration. Nitrite and nitrate concentrations were determined by reflectometric color measurement with a commercially available Reflectoquant® device. Correction factors for these media had to be determined. During the pilot development, bioreactors from 4 to 250 mg·L-1 and crossflow units with membrane areas from 0.02 to 0.80 m2 were examined. Based on the results of the pilot plants, a scaling for the exemplary process of denitrifying 1,000 tons per day is discussed. Y1 - 2010 U6 - https://doi.org/10.1002/btpr.384 SN - 8756-7938 VL - 26 IS - 3 SP - 756 EP - 762 PB - Wiley CY - Hoboken, NJ ER - TY - JOUR A1 - Nobis, Moritz A1 - Schmitt, Carlo A1 - Schemm, Ralf A1 - Schnettler, Armin T1 - Pan-European CVAR-constrained stochastic unit commitment in day-ahead and intraday electricity markets JF - Energies N2 - The fundamental modeling of energy systems through individual unit commitment decisions is crucial for energy system planning. However, current large-scale models are not capable of including uncertainties or even risk-averse behavior arising from forecasting errors of variable renewable energies. However, risks associated with uncertain forecasting errors have become increasingly relevant within the process of decarbonization. The intraday market serves to compensate for these forecasting errors. Thus, the uncertainty of forecasting errors results in uncertain intraday prices and quantities. Therefore, this paper proposes a two-stage risk-constrained stochastic optimization approach to fundamentally model unit commitment decisions facing an uncertain intraday market. By the nesting of Lagrangian relaxation and an extended Benders decomposition, this model can be applied to large-scale, e.g., pan-European, power systems. The approach is applied to scenarios for 2023—considering a full nuclear phase-out in Germany—and 2035—considering a full coal phase-out in Germany. First, the influence of the risk factors is evaluated. Furthermore, an evaluation of the market prices shows an increase in price levels as well as an increasing day-ahead-intraday spread in 2023 and in 2035. Finally, it is shown that intraday cross-border trading has a significant influence on trading volumes and prices and ensures a more efficient allocation of resources. Y1 - 2020 U6 - https://doi.org/10.3390/en13092339 SN - 1996-1073 N1 - Special Issue Uncertainties and Risk Management in Competitive Energy Markets VL - 13 IS - Art. 2339 SP - 1 EP - 35 PB - MDPI CY - Basel ER - TY - JOUR A1 - Stulpe, Werner T1 - Pairwise coexistence of effects versus coexistence JF - Journal of Physics: Conference Series Y1 - 2020 U6 - https://doi.org/10.1088/1742-6596/1638/1/012004 SN - 1742-6596 VL - 1638 IS - 012004 SP - 1 EP - 21 PB - IOP CY - Bristol ER - TY - JOUR A1 - Selmer, Thorsten A1 - Andrei, Paula I. T1 - p-Hydroxyphenylacetate decarboxylase from Clostridium difficile. A novel glycyl radical enzyme catalysing the formation of p-cresol JF - European Journal of Biochemistry. 268 (2001), H. 5 Y1 - 2001 SN - 0014-2956 SP - 1363 EP - 1372 ER - TY - JOUR A1 - Biselli, Manfred A1 - Born, C. A1 - Wandrey, C. T1 - Oxygen transfer from the gasphase to the immobilized cells in membrane aerated fluidized beds / Born, C. ; Biselli, M. ; Wandrey, C. JF - Animal cell technology : basic & applied aspects : proceedings of the Eighth Annual Meeting of the Japanese Association for Animal Cell Technology, Iizuka, Fukuoka, Japan, November 6-10, 1995 / edited by K. Funatsu, Y. Shirai, and T. Matsushita Y1 - 1995 SN - 0-7923-4486-3 N1 - Japanese Association for Animal Cell Technology. ; Meeting ; <8 ; 1995 : ; Iizuka-shi, Japan> SP - 83 EP - 87 PB - Kluwer Acad. Press CY - Boston ER - TY - JOUR A1 - Unden, G. A1 - Becker, S. A1 - Bongaerts, Johannes A1 - Schirawski, J. A1 - Six, S. T1 - Oxygen regulated gene expression in facultatively anaerobic bacteria JF - Antonie van Leeuwenhoek Y1 - 1994 SN - 0003-6072 (Print) ; 1572-9699 (online) VL - Vol. 66 IS - Iss. 1-3 SP - 3 EP - 22 ER - TY - JOUR A1 - Gun, Jenny A1 - Rizkov, Dan A1 - Lev, Ovadia A1 - Abouzar, Maryam H. A1 - Poghossian, Arshak A1 - Schöning, Michael Josef T1 - Oxygen plasma-treated gold nanoparticle-based field-effect devices as transducer structures for bio-chemical sensing JF - Microchimica Acta. 164 (2008), H. 3-4 Y1 - 2008 SN - 1436-5073 SP - 395 EP - 404 ER - TY - JOUR A1 - Selmer, Thorsten A1 - Buckel, Wolfgang T1 - Oxygen Exchange between Acetate and the Catalytic Glutamate Residue in Glutaconate CoA-transferase from Acidaminococcus fermentans. IMPLICATIONS FOR THE MECHANISM OF CoA-ESTER HYDROLYSIS JF - Journal of Biological Chemistry. 274 (1999), H. 30 Y1 - 1999 SN - 1083-351X SP - 20772 EP - 20778 ER - TY - JOUR A1 - Wittmann, Klaus T1 - Overview of Space Operations at DLR Y1 - 2000 N1 - SpaceOps2000 Conference, Toulouse, Frankreich,19-23 June 2000 ER - TY - JOUR A1 - von Häfen, Hajo A1 - Krautwald, Clemens A1 - Stolle, Jacob A1 - Bung, Daniel Bernhard A1 - Goseberg, Nils T1 - Overland flow of broken solitary waves over a two-dimensional coastal plane JF - Coastal Engineering N2 - Landslides, rock falls or related subaerial and subaqueous mass slides can generate devastating impulse waves in adjacent waterbodies. Such waves can occur in lakes and fjords, or due to glacier calving in bays or at steep ocean coastlines. Infrastructure and residential houses along coastlines of those waterbodies are often situated on low elevation terrain, and are potentially at risk from inundation. Impulse waves, running up a uniform slope and generating an overland flow over an initially dry adjacent horizontal plane, represent a frequently found scenario, which needs to be better understood for disaster planning and mitigation. This study presents a novel set of large-scale flume test focusing on solitary waves propagating over a 1:14.5 slope and breaking onto a horizontal section. Examining the characteristics of overland flow, this study gives, for the first time, insight into the fundamental process of overland flow of a broken solitary wave: its shape and celerity, as well as its momentum when wave breaking has taken place beforehand. KW - Landslide tsunamis KW - Hazard assessment KW - Large scale tests KW - Overland flow KW - Solitary waves Y1 - 2022 U6 - https://doi.org/10.1016/j.coastaleng.2022.104125 SN - 1872-7379 VL - 175 IS - August PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Boettcher, Martin A1 - Haselhuhn, Angelika A1 - Jakse, Gerhard A1 - Brehmer, Bernhard A1 - Kirschner-Hermanns, Ruth T1 - Overactive bladder syndrome: an underestimated long-term problem after treatment of patients with localized prostate cancer? JF - BJU international N2 - In this study we observed courses of micturition symptoms and differentiated degrees of symptoms for each point in time while also considering the impact of bothersomeness. Our data show that not only significantly more patients who have undergone BT suffer from OAB than those who have undergone RP, but also that those affected show significantly higher values for severity of OAB symptoms throughout the whole observation period of 36 months. Our data analysis further shows that variability of OAB symptoms as well as fluctuation of severity of OAB symptoms vary to a significantly higher degree after BT than after RP. Looking only at mean figures at a given point in time clearly underestimates the underlying problem. This fact is not reflected in the literature. KW - quality of life KW - prostate cancer KW - prostatectomy KW - incontinence KW - brachytherapy Y1 - 2012 U6 - https://doi.org/10.1111/j.1464-410X.2011.10623.x SN - 1365-2176 (E-Journal); 1464-410X (E-Journal); 0007-1331 (Print); 1464-4096 (Print) VL - 109 IS - 12 SP - 1824 EP - 1830 PB - Wiley-Blackwell CY - Oxford ER - TY - JOUR A1 - Janz, Norbert T1 - Outlier Robust Estimation of an Euler Equation Investment Model with German Firm Level Panel Data JF - Contributions to modern econometrics : from data analysis to economic policy ; [dedicated to Gerd Hansen on the occasion of his 65th Birthday] / ed. by Ingo Klein and Stefan Mittnik Y1 - 2002 SN - 1402073348 N1 - Dynamic modeling in econometrics in economics and finance ; 4 SP - 87 EP - 103 PB - Kluwer Academic Publ. CY - Dordrecht [u.a.] ER - TY - JOUR A1 - Laack, Walter van T1 - Our world is well ordered in measurement and number : or why natural constants are as they are JF - American Journal of Humanities and Social Sciences (AHSS) N2 - All the important natural constants can be logically explained with and derived from the first four ordinal numbers, 1, 2, 3 and 4, its addition to ten and finally the standard values for obviously maximal feasibility Ω and the optimum in our world, the Golden Section (GS), i.e. the number sequences 273 and 618. They both are the first three numbers of irrational results by an arithmetical transformation of simple geometrical relationships by creating multiplicity out of singularity. Both of them show that the infinite is inherent in finiteness and explain in a simple way the smallest deviations and fluctuations between the physical AS-IS state and the obvious spiritual ideal behind: Wherever we look in this world, and especially in important key-positions, we regularly find these sequences. All of the above mentioned numbers so seem to be key players in our world, what can be demonstrated by the derivation of natural constants. Y1 - 2013 U6 - https://doi.org/10.11634/232907811301390 SN - 2329-079X SN - 2329-0781 VL - 1 IS - 4 SP - 219 EP - 221 ER - TY - JOUR A1 - Rausch, Valentin A1 - Harbrecht, Andreas A1 - Kahmann, Stephanie Lucina A1 - Fenten, Thomas A1 - Jovanovic, Nebojsa A1 - Hackl, Michael A1 - Müller, Lars P. A1 - Staat, Manfred A1 - Wegmann, Kilian T1 - Osteosynthesis of Phalangeal Fractures: Biomechanical Comparison of Kirschner Wires, Plates, and Compression Screws JF - The Journal of Hand Surgery N2 - Purpose The aim of this study was to compare several osteosynthesis techniques (intramedullary headless compression screws, T-plates, and Kirschner wires) for distal epiphyseal fractures of proximal phalanges in a human cadaveric model. Methods A total of 90 proximal phalanges from 30 specimens (index, ring, and middle fingers) were used for this study. After stripping off all soft tissue, a transverse distal epiphyseal fracture was simulated at the proximal phalanx. The 30 specimens were randomly assigned to 1 fixation technique (30 per technique), either a 3.0-mm intramedullary headless compression screw, locking plate fixation with a 2.0-mm T-plate, or 2 oblique 1.0-mm Kirschner wires. Displacement analysis (bending, distraction, and torsion) was performed using optical tracking of an applied random speckle pattern after osteosynthesis. Biomechanical testing was performed with increasing cyclic loading and with cyclic load to failure using a biaxial torsion-tension testing machine. Results Cannulated intramedullary compression screws showed significantly less displacement at the fracture site in torsional testing. Furthermore, screws were significantly more stable in bending testing. Kirschner wires were significantly less stable than plating or screw fixation in any cyclic load to failure test setup. Conclusions Intramedullary compression screws are a highly stable alternative in the treatment of transverse distal epiphyseal phalangeal fractures. Kirschner wires seem to be inferior regarding displacement properties and primary stability. Clinical relevance Fracture fixation of phalangeal fractures using plate osteosynthesis may have the advantage of a very rigid reduction, but disadvantages such as stiffness owing to the more invasive surgical approach and soft tissue irritation should be taken into account. Headless compression screws represent a minimally invasive choice for fixation with good biomechanical properties. Y1 - 2020 U6 - https://doi.org/10.1016/j.jhsa.2020.04.010 SN - 0363-5023 VL - 45 IS - 10 SP - 987.e1 EP - 987.e8 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Janz, Norbert T1 - Ostdeutschland: Dienstleister sind Schwachstelle JF - EU-Magazin : unabhängige Zeitschrift für Wirtschaft, Recht und Politik in der Europäischen Union ; mit ZEW aktuell. 8 (2001), H. 10 Y1 - 2001 SN - 0946-4689 SP - 3 EP - 3 ER - TY - JOUR A1 - Fissabre, Anke A1 - Hertwig, Christine A1 - Schmidt, Klaus A1 - Sonnleitner, Andrea T1 - Ortrand : Das Lehnsmühlschloss : Ein Herrenhaus des 16. Jahrhunderts JF - Brandenburgische Denkmalpflege Y1 - 2002 SN - 0942-3397 IS - 2 SP - 29 EP - 42 ER - TY - JOUR A1 - Scholl, Ingrid A1 - Conradi, Helmut A1 - Wirtz, D. A1 - Spreckelsen, Cord T1 - OrthoDocs - Ein modellbasiertes Werkzeug zur Erstellung orthopädischer Lerndokumente. Conradi, Helmar; Wirtz, D.; Spreckelsen, Cord; Scholl, Ingrid; Kreutz, Reinhard; Forst, R.; Spitzer, Klaus JF - Medizinische Informatik, Biometrie und Epidemiologie, GMDS '96, 41. Jahrestagung der GMDS, Bonn, September 1996 Y1 - 1997 SN - 3820812954 SP - 169 EP - 173 PB - MVV, Medizin-Verl. CY - München ER - TY - JOUR A1 - Eilmann, Britta A1 - de Vries, Sven M. G. A1 - den Ouden, Jan A1 - Mohren, Godefridus M. J. A1 - Sauren, Pascal A1 - Sass-Klaassen, Ute G. W. T1 - Origin matters! Difference in drought tolerance and productivity of coastal Douglas-fir (Pseudotsuga menziesii (Mirb.)) provenances JF - Forest Ecology and Management Y1 - 2013 U6 - https://doi.org/doi:10.1016/j.foreco.2013.03.031 SN - 1872-7042 (Online) SN - 0378-1127 (Print) VL - 2013 IS - 302 SP - 133 EP - 143 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Scholl, Ingrid A1 - Kreutz, Reinhard A1 - Conradi, Helmut A1 - Spitzer, Klaus T1 - Orientierungs- und Benutzerunterstützung in Web-Dokumenten. Kreutz, Reinhard; Conradi, Helmut; Scholl, Ingrid; Spitzer, Klaus JF - Informatik '97 : Informatik als Innovationsmotor ; 27. Jahrestagung der Gesellschaft für Informatik Aachen, 24. - 26. September 1997 / Hrsg.: Matthias Jarke ... Y1 - 1997 SN - 3-540-63066-X SP - 516 EP - 517 PB - Springer CY - Berlin ER - TY - JOUR A1 - Thielemann, Frank A1 - Bock, Jürgen T1 - Organization and management of German-Russian joint ventures. Bock, Jürgen; Thielemann, Frank JF - International journal of technology management. 9 (1994), H. 8 Y1 - 1994 SN - 0267-5730 SP - 864 EP - 879 ER - TY - JOUR A1 - Köhler, Klemens A1 - Wolf, Martin R. T1 - Organisatorische Maßnahmen zu Erhöhung der IT Sicherheit – Empfehlungen aus der Perspektive der Konflikttheorie N2 - Die NATO definiert den Cyberspace als die "Umgebung, die durch physische und nicht-physische Bestandteile zum Speichern, Ändern, und Austauschen von Daten mit Hilfe von Computer-Netzwerken" [NATO CCDCOE]. Darüber hinaus ist es ein Medium menschlicher Interaktion. IT Angriffe sind feindselige, nichtkooperative Interaktionen, die mittels Konflikttheorie beschrieben werden können. Durch die Anwendung dieses Gedankengebäudes auf IT Sicherheit von Organisationen können eine Reihe von Verbesserungen in Unternehmen identifiziert werden. Y1 - 2020 IS - Preprint ER - TY - JOUR A1 - Sponagel, Stefan A1 - Unger, J. T1 - Organisation und Strukturierung technischer Messungen JF - Werkstattstechnik. 88 (1998), H. 5 Y1 - 1998 SN - 1436-5006 SP - 223 EP - 226 ER - TY - JOUR A1 - Penner, Crystal A1 - Usherovich, Samuel A1 - Niedermeier, Jana A1 - Bélanger-Champagne, Camille A1 - Trinczek, Michael A1 - Paulßen, Elisabeth A1 - Hoehr, Cornelia T1 - Organic Scintillator-Fibre Sensors for Proton Therapy Dosimetry: SCSF-3HF and EJ-260 JF - electronics N2 - In proton therapy, the dose from secondary neutrons to the patient can contribute to side effects and the creation of secondary cancer. A simple and fast detection system to distinguish between dose from protons and neutrons both in pretreatment verification as well as potentially in vivo monitoring is needed to minimize dose from secondary neutrons. Two 3 mm long, 1 mm diameter organic scintillators were tested for candidacy to be used in a proton–neutron discrimination detector. The SCSF-3HF (1500) scintillating fibre (Kuraray Co. Chiyoda-ku, Tokyo, Japan) and EJ-260 plastic scintillator (Eljen Technology, Sweetwater, TX, USA) were irradiated at the TRIUMF Neutron Facility and the Proton Therapy Research Centre. In the proton beam, we compared the raw Bragg peak and spread-out Bragg peak response to the industry standard Markus chamber detector. Both scintillator sensors exhibited quenching at high LET in the Bragg peak, presenting a peak-to-entrance ratio of 2.59 for the EJ-260 and 2.63 for the SCSF-3HF fibre, compared to 3.70 for the Markus chamber. The SCSF-3HF sensor demonstrated 1.3 times the sensitivity to protons and 3 times the sensitivity to neutrons as compared to the EJ-260 sensor. Combined with our equations relating neutron and proton contributions to dose during proton irradiations, and the application of Birks’ quenching correction, these fibres provide valid candidates for inexpensive and replicable proton-neutron discrimination detectors Y1 - 2022 U6 - https://doi.org/10.3390/electronics12010011 SN - 2079-9292 N1 - This article belongs to the Special Issue "Applications of Optical Fiber Sensors" VL - 12 IS - 1 PB - MDPI CY - Basel ER - TY - JOUR A1 - Sadykov, Rustam A1 - Digel, Ilya A1 - Temiz Artmann, Aysegül A1 - Porst, Dariusz A1 - Linder, Peter A1 - Kayser, Peter A1 - Artmann, Gerhard A1 - Savitskaya, Irina A1 - Zhubanova, Azhar T1 - Oral lead exposure induces dysbacteriosis in rats JF - Journal of Occupational Health. 51 (2009) (2009), H. 1 Y1 - 2009 SN - 1348-9585 SP - 64 EP - 73 ER - TY - JOUR A1 - Pita, Marcos A1 - Krämer, Melina A1 - Zouh, Jian A1 - Poghossian, Arshak A1 - Schöning, Michael Josef A1 - Fernandez, Victor M. A1 - Katz, Evgeny T1 - Optoelectronic Properties of Nanostructured Ensembles Controlled by Biomolecular Logic Systems JF - ACS Nano. 10 (2008), H. 2 Y1 - 2008 SN - 1936-086X SP - 2160 EP - 2166 ER - TY - JOUR A1 - Starke, Günther A1 - Drews, P. T1 - Optisch-elektronischer Nahtfuehrungssensor zur Schweissnahtverfolgung JF - Technisches Messen tm. 51 (1984), H. 7/8 Y1 - 1984 SN - 0171-8096 SP - 270 EP - 275 ER - TY - JOUR A1 - Ferrein, Alexander A1 - Böhnstedt, Lutz A1 - Lakemeyer, Gerhard T1 - Options in readylog reloaded -- generating decision-theoretic plan libraries in golog / Böhnstedt, Lutz ; Ferrein, Alexander ; Lakemeyer, Gerhard JF - KI 2007: advances in artificial intelligence : 30th Annual German Conference on AI, KI 2007, Osnabrück, Germany, September 10 - 13, 2007 ; proceedings Y1 - 2007 SN - 978-3-540-74564-8 N1 - Lecture Notes in Computer Science ; 4667 SP - 352 EP - 366 PB - Springer CY - Berlin ER - TY - JOUR A1 - Benkner, Thorsten T1 - Optimum Transmission Power in High Capacity Umbrella Cell Systems JF - Multiaccess, mobility and teletraffic : advances in wireless networks ; [proceedings of the Third Workshop on Multiaccess, Mobility and Teletraffic for Personal Communications held in December 1997 in Melbourne, Australia] / ed. by David Everitt ... Y1 - 1998 SN - 0-7923-8091-6 N1 - Workshop on Multiaccess, Mobility and Teletraffic for Personal Communications <3, 1997, Melbourne> SP - 221 EP - 232 PB - Kluwer CY - Boston, Mass. [u.a.] ER - TY - JOUR A1 - Engels, Elmar A1 - Doege, E. T1 - Optimizing the number of strokes for punching machines using a fuzzy controlled electrohydraulic damping system / Doege, E. ; Engels, E. JF - ICME 98, CIRP International Seminar on Intelligent Computation in Manufacturing Engineering, Proceedings, Capri, IT, Jul 1-3, 1998 Y1 - 1998 SP - 471 EP - 478 CY - Capri ER - TY - JOUR A1 - Dachwald, Bernd A1 - Carnelli, I. A1 - Vasile, M. T1 - Optimizing low-thrust gravity assist interplanetary trajectories using evolutionary neurocontrollers / I. Carnelli ; B. Dachwald ; M. Vasile JF - IEEE Congress on Evolutionary Computation, 2007 : CEC 2007 ; 25 - 28 September 2007, Singapore Y1 - 2007 SN - 978-1-424-41339-3 N1 - ISBN 10: 1-424-41339-7 ; IEEE Congress on Evolutionary Computation <2007, Singapore> ; Institute of Electrical and Electronics Engineers ; Nebent: CEC 2007 ; Parallel als Online-Ausg. erschienen SP - 965 EP - 972 PB - IEEE Service Center CY - Piscataway, NJ ER - TY - JOUR A1 - Hugenroth, Kristin A1 - Borchardt, Ralf A1 - Ritter, Philine A1 - Groß‑Hardt, Sascha A1 - Meyns, Bart A1 - Verbelen, Tom A1 - Steinseifer, Ulrich A1 - Kaufmann, Tim A. S. A1 - Engelmann, Ulrich M. T1 - Optimizing cerebral perfusion and hemodynamics during cardiopulmonary bypass through cannula design combining in silico, in vitro and in vivo input JF - Scientific Reports N2 - Cardiopulmonary bypass (CPB) is a standard technique for cardiac surgery, but comes with the risk of severe neurological complications (e.g. stroke) caused by embolisms and/or reduced cerebral perfusion. We report on an aortic cannula prototype design (optiCAN) with helical outflow and jet-splitting dispersion tip that could reduce the risk of embolic events and restores cerebral perfusion to 97.5% of physiological flow during CPB in vivo, whereas a commercial curved-tip cannula yields 74.6%. In further in vitro comparison, pressure loss and hemolysis parameters of optiCAN remain unaffected. Results are reproducibly confirmed in silico for an exemplary human aortic anatomy via computational fluid dynamics (CFD) simulations. Based on CFD simulations, we firstly show that optiCAN design improves aortic root washout, which reduces the risk of thromboembolism. Secondly, we identify regions of the aortic intima with increased risk of plaque release by correlating areas of enhanced plaque growth and high wall shear stresses (WSS). From this we propose another easy-to-manufacture cannula design (opti2CAN) that decreases areas burdened by high WSS, while preserving physiological cerebral flow and favorable hemodynamics. With this novel cannula design, we propose a cannulation option to reduce neurological complications and the prevalence of stroke in high-risk patients after CPB. Y1 - 2021 U6 - https://doi.org/10.1038/s41598-021-96397-2 SN - 2045-2322 VL - 11 IS - Art. No. 16800 SP - 1 EP - 12 PB - Springer CY - Berlin ER - TY - JOUR A1 - Esch, Thomas T1 - Optimized design of the lubrication system of modern combustion engines. Verbesserte Ausführung von Schmierungssystemen bei modernen Verbrennungsmotoren Y1 - 1991 SN - 0148-7191 U6 - https://doi.org/10.4271/912407 N1 - Konferenz-Einzelbericht : SAE technical papers / Society of Automotive Engineers, Paper-Nr. 912407 SP - 1 EP - 11 ER - TY - JOUR A1 - Bank, Bart L. van de A1 - Orzada, Stephan A1 - Smits, Frits A1 - Lagemaat, Miriam W. A1 - Rodgers, Christopher T. A1 - Bitz, Andreas A1 - Scheenen, Tom W. J. T1 - Optimized (31) P MRS in the human brain at 7 T with a dedicated RF coil setup JF - NMR in Biomedicine Y1 - 2015 U6 - https://doi.org/10.1002/nbm.3422 SN - 1099-1492 VL - 28 IS - 11 SP - 1570 EP - 1578 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Dachwald, Bernd T1 - Optimization of very-low-thrust trajectories using evolutionary neurocontrol JF - Acta Astronautica N2 - Searching optimal interplanetary trajectories for low-thrust spacecraft is usually a difficult and time-consuming task that involves much experience and expert knowledge in astrodynamics and optimal control theory. This is because the convergence behavior of traditional local optimizers, which are based on numerical optimal control methods, depends on an adequate initial guess, which is often hard to find, especially for very-low-thrust trajectories that necessitate many revolutions around the sun. The obtained solutions are typically close to the initial guess that is rarely close to the (unknown) global optimum. Within this paper, trajectory optimization problems are attacked from the perspective of artificial intelligence and machine learning. Inspired by natural archetypes, a smart global method for low-thrust trajectory optimization is proposed that fuses artificial neural networks and evolutionary algorithms into so-called evolutionary neurocontrollers. This novel method runs without an initial guess and does not require the attendance of an expert in astrodynamics and optimal control theory. This paper details how evolutionary neurocontrol works and how it could be implemented. The performance of the method is assessed for three different interplanetary missions with a thrust to mass ratio <0.15mN/kg (solar sail and nuclear electric). Y1 - 2005 SN - 1879-2030 VL - 57 IS - 2-8 SP - 175 EP - 185 PB - Elsevier CY - Amsterdam [u.a.] ER - TY - JOUR A1 - Dachwald, Bernd T1 - Optimization of very-low-thrust trajectories using evolutionary neurocontrol JF - Acta Astronautica. 57 (2005), H. 2-8 Y1 - 2005 SN - 0094-5765 SP - 175 EP - 185 ER - TY - JOUR A1 - Arreola, Julio A1 - Mätzkow, Malte A1 - Durán, Marlena Palomar A1 - Greeff, Anton A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Optimization of the immobilization of bacterial spores on glass substrates with organosilanes JF - Physica status solidi (A) : Applications and materials science N2 - Spores can be immobilized on biosensors to function as sensitive recognition elements. However, the immobilization can affect the sensitivity and reproducibility of the sensor signal. In this work, three different immobilization strategies with organosilanes were optimized and characterized to immobilize Bacillus atrophaeus spores on glass substrates. Five different silanization parameters were investigated: nature of the solvent, concentration of the silane, silanization time, curing process, and silanization temperature. The resulting silane layers were resistant to a buffer solution (e.g., Ringer solution) with a polysorbate (e.g., Tween®80) and sonication. KW - silanization KW - organosilanes KW - immobilization KW - endospores KW - biosensors KW - Bacillus atrophaeus Y1 - 2016 U6 - https://doi.org/10.1002/pssa.201532914 SN - 1862-6319 VL - 213 IS - 6 SP - 1463 EP - 1470 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Alexopoulos, Spiros A1 - Breitbach, Gerd A1 - Hoffschmidt, Bernhard A1 - Stobbe, P. T1 - Optimization of the geometry of porous SiC ceramic filtering modules using numerical methods JF - Developments in porous, biological and geopolymer ceramics : a collection of papers presented at the 31st International Conference on Advanced Ceramics and Composites, January 21 - 26, 2007, Daytona Beach, Florida ; [papers presented at the Symposium on Porous Ceramics: Novel Developments and Applications] / ed.: Manuel Brito ... Vol. ed.: Jonathan Salem ... The American Ceramics Society Y1 - 2008 SN - 9780470196403 N1 - Ceramic engineering and science proceedings ; 28,9 SP - 95 EP - 104 PB - Wiley CY - Hoboken, NJ ER - TY - JOUR A1 - Jung, Alexander A1 - Müller, Wolfram A1 - Staat, Manfred T1 - Optimization of the flight technique in ski jumping: the influence of wind Y1 - 2019 U6 - https://doi.org/10.1016/j.jbiomech.2019.03.023 IS - Early view PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Hoffstadt, Kevin A1 - Nikolausz, Marcell A1 - Krafft, Simone A1 - Bonatelli, Maria A1 - Kumar, Vivekanantha A1 - Harms, Hauke A1 - Kuperjans, Isabel T1 - Optimization of the ex situ biomethanation of hydrogen and carbon dioxide in a novel meandering plug flow reactor: start-up phase and flexible operation JF - Bioengineering KW - methanation KW - plug flow reactor KW - bubble column KW - biomethane KW - P2G Y1 - 2024 U6 - https://doi.org/10.3390/bioengineering11020165 SN - 2306-5354 VL - 11 IS - 2 PB - MDPI CY - Basel ER - TY - JOUR A1 - Degering, Christian A1 - Eggert, Thorsten A1 - Puls, Michael A1 - Bongaerts, Johannes A1 - Evers, Stefan A1 - Maurer, Karl-Heinz A1 - Jaeger, Karl-Erich T1 - Optimization of protease secretion in Bacillus subtilis and Bacillus licheniformis by screening of homologous and herologous signal peptides JF - Applied and environmental microbiology N2 - Bacillus subtilis and Bacillus licheniformis are widely used for the large-scale industrial production of proteins. These strains can efficiently secrete proteins into the culture medium using the general secretion (Sec) pathway. A characteristic feature of all secreted proteins is their N-terminal signal peptides, which are recognized by the secretion machinery. Here, we have studied the production of an industrially important secreted protease, namely, subtilisin BPN′ from Bacillus amyloliquefaciens. One hundred seventy-three signal peptides originating from B. subtilis and 220 signal peptides from the B. licheniformis type strain were fused to this secretion target and expressed in B. subtilis, and the resulting library was analyzed by high-throughput screening for extracellular proteolytic activity. We have identified a number of signal peptides originating from both organisms which produced significantly increased yield of the secreted protease. Interestingly, we observed that levels of extracellular protease were improved not only in B. subtilis, which was used as the screening host, but also in two different B. licheniformis strains. To date, it is impossible to predict which signal peptide will result in better secretion and thus an improved yield of a given extracellular target protein. Our data show that screening a library consisting of homologous and heterologous signal peptides fused to a target protein can identify more-effective signal peptides, resulting in improved protein export not only in the original screening host but also in different production strains. Y1 - 2010 U6 - https://doi.org/10.1128/AEM.01146-10 SN - 1098-5336 (E-Journal); 0003-6919 (Print); 0099-2240 (Print) VL - 76 IS - 19 SP - 6370 EP - 6378 PB - American Society for Microbiology CY - Washington, DC ER - TY - JOUR A1 - Faßbender, F. A1 - Schmitt, G. A1 - Schöning, Michael Josef A1 - Lüth, H. A1 - Buß, G. A1 - Schultze, J. W. T1 - Optimization of passivation layers for corrosion protection of silicon-based microelectrode arrays JF - Sensors and Actuators B. 68 (2000), H. 1-3 Y1 - 2000 SN - 0925-4005 SP - 128 EP - 133 ER - TY - JOUR A1 - Dachwald, Bernd A1 - Ohndorf, A. A1 - Gill, E. T1 - Optimization of low-thrust Earth-Moon transfers using evolutionary neurocontrol / Ohndorf, A. ; Dachwald, B. ; Gill, E. JF - IEEE Congress on Evolutionary Computation, 2009. CEC '09. Y1 - 2009 SN - 978-1-4244-2958-5 SP - 358 EP - 364 ER - TY - JOUR A1 - Reisgen, Uwe A1 - Schleser, Markus A1 - Mokrov, Oleg A1 - Ahmed, Essam T1 - Optimization of laser welding of DP/TRIP steel sheets using statistical approach JF - Optics and laser technology N2 - Generally, the quality of a weld joint is directly influenced by the welding input parameter settings. Selection of proper process parameters is important to obtain the desired weld bead profile and quality. In this research work, numerical and graphical optimization techniques of the CO2 laser beam welding of dual phase (DP600)/transformation induced plasticity (TRIP700) steel sheets were carried out using response surface methodology (RSM) based on Box–Behnken design. The procedure was established to improve the weld quality, increase the productivity and minimize the total operation cost by considering the welding parameters range of laser power (2–2.2 kW), welding speed (40–50 mm/s) and focus position (−1 to 0 mm). It was found that, RSM can be considered as a powerful tool in experimental welding optimization, even when the experimenter does not have a model for the process. Strong, efficient and low cost weld joints could be achieved using the optimum welding conditions. Y1 - 2012 U6 - https://doi.org/10.1016/j.optlastec.2011.06.028 SN - 1879-2545 (E-Journal); 0030-3992 (Print); 0308-4280 (Print) VL - 44 IS - 1 SP - 255 EP - 262 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Dachwald, Bernd T1 - Optimization of Interplanetary Solar Sailcraft Trajectories Using Evolutionary Neurocontrol JF - Journal of guidance, control, and dynamics. 27 (2004), H. 1 Y1 - 2004 SN - 0162-3192 N1 - 2. ISSN: 0162-3192. - 3. ISSN: 0731-5090 SP - 66 EP - 72 ER - TY - JOUR A1 - Dachwald, Bernd A1 - Seboldt, Wolfgang T1 - Optimization of Interplanetary Rendezvous Trajectories for Solar Sailcraft Using a Neurocontroller JF - A collection of technical papers / AIAA Astrodynamics Specialist Conference : Monterey, California, 5 - 8 August 2002. - Vol. 2 Y1 - 2002 SN - 1-56347-549-9 N1 - Astrodynamics Specialist Conference <2002, Monterey, Calif.> American Institute of Aeronautics and Astronautics ; AIAA paper number: AIAA-2002-4989 SP - 1263 EP - 1270 PB - American Institute of Aeronautics and Astronautics CY - Reston, Va. ER - TY - JOUR A1 - Ungermanns, C. A1 - Ahe, M. v. d. A1 - Carius, Reinhard A1 - Förster, Arnold T1 - Optimization of III/V binary growth with RHEED in MOMBE / C. Ungermanns ; M. v. d. Ahe ; R. Carius ; A. Förster ... JF - Fresenius' Journal of Analytical Chemistry. 358 (1997), H. 1-2 Y1 - 1997 SN - 0937-0633 N1 - ISSN der E-Ausg.: 1432-1130 SP - 101 EP - 104 ER - TY - JOUR A1 - Pasteur, Aline A1 - Tippkötter, Nils A1 - Kampeis, Percy A1 - Ulber, Roland T1 - Optimization of high gradient magnetic separation filter units for the purification of fermentation products JF - IEEE TRANSACTIONS ON MAGNETICS N2 - High gradient magnetic separation (HGMS) has been established since the early 1970s. A more recent application of these systems is the use in bioprocesses. To integrate the HGMS in a fermentation process, it is necessary to optimize the separation matrix with regard to the magnetic separation characteristics and permeability of the non-magnetizable components of the fermentation broth. As part of the work presented here, a combined fluidic and magnetic force finite element model simulation was created using the software COMSOL Multiphysics and compared with separation experiments. Finally, as optimal lattice orientation of the separation matrix, a transversal rhombohedral arrangement was defined. The high suitability of the new filter matrix has been verified by separation experiments. Y1 - 2014 U6 - https://doi.org/10.1109/TMAG.2014.2325535 SN - 0018-9464 N1 - Article Sequence Number: 5000607 INSPEC Accession Number: 14663042 VL - 50 IS - 10 SP - Artikel 5000607 PB - IEEE CY - New York, NY ER - TY - JOUR A1 - Dantism, Shahriar A1 - Röhlen, Desiree A1 - Wagner, Torsten A1 - Wagner, Patrick A1 - Schöning, Michael Josef T1 - Optimization of Cell-Based Multi-Chamber LAPS Measurements Utilizing FPGA-Controlled Laser-Diode Modules JF - physica status solidi a : applications and materials sciences N2 - A light-addressable potentiometric sensor (LAPS) is a field-effect-based potentiometric device, which detects concentration changes of an analyte solution on the sensor surface in a spatially resolved way. It uses a light source to generate electron–hole pairs inside the semiconductor, which are separated in the depletion region due to an applied bias voltage across the sensor structure and hence, a surface-potential-dependent photocurrent can be read out. However, depending on the beam angle of the light source, scattering effects can occur, which influence the recorded signal in LAPS-based differential measurements. To solve this problem, a novel illumination unit based on a field programmable gate array (FPGA) consisting of 16 small-sized tunable infrared laser-diode modules (LDMs) is developed. Due to the improved focus of the LDMs with a beam angle of only 2 mrad, undesirable scattering effects are minimized. Escherichia coli (E. coli) K12 bacteria are used as a test microorganism to study the extracellular acidification on the sensor surface. Furthermore, a salt bridge chamber is built up and integrated with the LAPS system enabling multi-chamber differential measurements with a single Ag/AgCl reference electrode. Y1 - 2018 U6 - https://doi.org/10.1002/pssa.201800058 SN - 1862-6319 VL - 215 IS - 15 SP - Article number 1800058 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Biselli, Manfred A1 - Rolef, G. A1 - Dunker, R. A1 - Wandrey, Christian T1 - Optimization of antibody production in a fluidized bed bioreactor / Rolef, G. ; Biselli, M. ; Dunker, R. ; Wandrey, C. JF - Animal cell technology : products of today, prospects for tomorrow ; ESACT, European Society for Animal Cell Technology, the 12th meeting / Ed. R. E. Spier Y1 - 1994 SN - 0750618450 N1 - Meeting / European Society for Animal Cell Technology ; 12 SP - 481 EP - 484 PB - Butterworth-Heinemann CY - Oxford ER - TY - JOUR A1 - Pilas, Johanna A1 - Mariano, K. A1 - Keusgen, M. A1 - Selmer, Thorsten A1 - Schöning, Michael Josef T1 - Optimization of an Enzyme-based Multi-parameter Biosensor for Monitoring Biogas Processes JF - Procedia Engineering Y1 - 2015 U6 - https://doi.org/10.1016/j.proeng.2015.08.702 SN - 1877-7058 N1 - Part of special issue "Eurosensors 2015" VL - 120 SP - 532 EP - 535 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Pilas, Johanna A1 - Yazici, Yasemen A1 - Selmer, Thorsten A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Optimization of an amperometric biosensor array for simultaneous measurement of ethanol, formate, d- and l-lactate JF - Electrochimica Acta N2 - The immobilization of NAD+-dependent dehydrogenases, in combination with a diaphorase, enables the facile development of multiparametric sensing devices. In this work, an amperometric biosensor array for simultaneous determination of ethanol, formate, d- and l-lactate is presented. Enzyme immobilization on platinum thin-film electrodes was realized by chemical cross-linking with glutaraldehyde. The optimization of the sensor performance was investigated with regard to enzyme loading, glutaraldehyde concentration, pH, cofactor concentration and temperature. Under optimal working conditions (potassium phosphate buffer with pH 7.5, 2.5 mmol L-1 NAD+, 2.0 mmol L-1 ferricyanide, 25 °C and 0.4% glutaraldehyde) the linear working range and sensitivity of the four sensor elements was improved. Simultaneous and cross-talk free measurements of four different metabolic parameters were performed successfully. The reliable analytical performance of the biosensor array was demonstrated by application in a clarified sample of inoculum sludge. Thereby, a promising approach for on-site monitoring of fermentation processes is provided. KW - Simultaneous determination KW - Enzymatic biosensor KW - Diaphorase KW - Dehydrogenase Y1 - 2017 U6 - https://doi.org/10.1016/j.electacta.2017.07.119 SN - 0013-4686 VL - 251 SP - 256 EP - 262 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Müller, Tim M. A1 - Leise, Philipp A1 - Lorenz, Imke-Sophie A1 - Altherr, Lena A1 - Pelz, Peter F. T1 - Optimization and validation of pumping system design and operation for water supply in high-rise buildings JF - Optimization and Engineering N2 - The application of mathematical optimization methods for water supply system design and operation provides the capacity to increase the energy efficiency and to lower the investment costs considerably. We present a system approach for the optimal design and operation of pumping systems in real-world high-rise buildings that is based on the usage of mixed-integer nonlinear and mixed-integer linear modeling approaches. In addition, we consider different booster station topologies, i.e. parallel and series-parallel central booster stations as well as decentral booster stations. To confirm the validity of the underlying optimization models with real-world system behavior, we additionally present validation results based on experiments conducted on a modularly constructed pumping test rig. Within the models we consider layout and control decisions for different load scenarios, leading to a Deterministic Equivalent of a two-stage stochastic optimization program. We use a piecewise linearization as well as a piecewise relaxation of the pumps’ characteristics to derive mixed-integer linear models. Besides the solution with off-the-shelf solvers, we present a problem specific exact solving algorithm to improve the computation time. Focusing on the efficient exploration of the solution space, we divide the problem into smaller subproblems, which partly can be cut off in the solution process. Furthermore, we discuss the performance and applicability of the solution approaches for real buildings and analyze the technical aspects of the solutions from an engineer’s point of view, keeping in mind the economically important trade-off between investment and operation costs. KW - Technical Operations Research KW - MINLP KW - MILP KW - Experimental validation KW - Pumping systems Y1 - 2020 U6 - https://doi.org/10.1007/s11081-020-09553-4 SN - 1573-2924 VL - 2021 IS - 22 SP - 643 EP - 686 PB - Springer ER - TY - JOUR A1 - Kern, Alexander A1 - Klöters, Georg A1 - Pferdemenges, Jörg T1 - Optimised protection against lightning for the signalling and safety systems of level crossings on non-electrified railway lines JF - RTR : European Rail Technology Review Y1 - 2010 SN - 0079-9548 VL - 50 IS - 2 ER - TY - JOUR A1 - Damm, Marc André A1 - Sauerborn, Markus A1 - Fend, Thomas A1 - Herrmann, Ulf T1 - Optimisation of a urea selective catalytic reduction system with a coated ceramic mixing element JF - Journal of ceramic science and technology Y1 - 2017 SN - 2190-9385 (Print) U6 - https://doi.org/10.4416/JCST2016-00056 SN - 2190-9385 (Online) VL - 8 IS - 1 SP - 19 EP - 24 PB - Göller CY - Baden-Baden ER - TY - JOUR A1 - Kirchner, Patrick A1 - Oberländer, Jan A1 - Friedrich, Peter A1 - Berger, Jörg A1 - Suso, Henri-Pierre A1 - Kupyna, Andriy A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Optimisation and fabrication of a calorimetric gas sensor built up on a polyimide substrate for H2O2 monitoring JF - Physica status solidi (a) : applications and material science. 208 (2011), H. 6 Y1 - 2011 SN - 1862-6319 SP - 1235 EP - 1240 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Schwarzer, Klemens A1 - Hafner, B. A1 - Krings, D. T1 - Optimierung von solarthermischen Kochersystemen JF - Energiewirtschaftliche Tagesfragen. 44 (1994), H. 9 Y1 - 1994 SN - 0720-6240 SP - 44 EP - 46 ER - TY - JOUR A1 - Dachwald, Bernd A1 - Ohndorf, A. A1 - Seboldt, Wolfgang T1 - Optimierung der Lageregelung von Raumfahrzeugen mit Niedrigschubantrieb mittels evolutionärer neuronaler Regler / A. Ohndorf ; B. Dachwald ; W. Seboldt JF - Deutscher Luft- und Raumfahrtkongress 2005 : Friedrichshafen, 26. bis 29. September 2005, Motto: Luft- und Raumfahrt - Grenzen überwinden, Horizonte erweitern / Deutsche Gesellschaft für Luft- und Raumfahrt - Lilienthal-Oberth e.V. (DGLR). [Red.: Peter Brandt (verantwortlich)]. Bd. 3. - (Jahrbuch ... der Deutschen Gesellschaft für Luft- und Raumfahrt Y1 - 2005 N1 - Deutscher Luft- und Raumfahrt-Kongress <2005, Friedrichshafen> ; Deutsche Gesellschaft für Luft- und Raumfahrt - Lilienthal-Oberth ; Dokumentnr: DGLR-2005-224 SP - 1971 EP - 1978 PB - DGLR CY - Bonn ER - TY - JOUR A1 - Weigand, Christoph T1 - Optimale Maschinenjustierung JF - Technische Hochschule / Bibliothek: Wissenschaftliche Zeitschrift. 37 (1991) Y1 - 1991 SN - 0043-6917 SP - 167 EP - 175 ER -