TY  - JOUR
A1  - Kahmann, Stephanie L.
A1  - Rausch, Valentin
A1  - Plümer, Jonathan
A1  - Müller, Lars P.
A1  - Pieper, Martin
A1  - Wegmann, Kilian
T1  - The automized fracture edge detection and generation of three-dimensional fracture probability heat maps
JF  - Medical Engineering & Physics
N2  - With proven impact of statistical fracture analysis on fracture classifications, it is desirable to minimize the manual work and to maximize repeatability of this approach. We address this with an algorithm that reduces the manual effort to segmentation, fragment identification and reduction. The fracture edge detection and heat map generation are performed automatically. With the same input, the algorithm always delivers the same output. The tool transforms one intact template consecutively onto each fractured specimen by linear least square optimization, detects the fragment edges in the template and then superimposes them to generate a fracture probability heat map.

We hypothesized that the algorithm runs faster than the manual evaluation and with low (< 5 mm) deviation. We tested the hypothesis in 10 fractured proximal humeri and found that it performs with good accuracy (2.5 mm ± 2.4 mm averaged Euclidean distance) and speed (23 times faster). When applied to a distal humerus, a tibia plateau, and a scaphoid fracture, the run times were low (1–2 min), and the detected edges correct by visual judgement. In the geometrically complex acetabulum, at a run time of 78 min some outliers were considered acceptable. An automatically generated fracture probability heat map based on 50 proximal humerus fractures matches the areas of high risk of fracture reported in medical literature.

Such automation of the fracture analysis method is advantageous and could be extended to reduce the manual effort even further.
KW  - Fracture classification
KW  - Shoulder
KW  - Probability distribution mapping
KW  - Morphing
KW  - Imaging
Y1  - 2022
SN  - 1350-4533
VL  - 2022
IS  - 110
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Moret, J.L.T.M.
A1  - Alkemade, J.
A1  - Upcraft, T.M.
A1  - Paulßen, Elisabeth
A1  - Wolterbeek, H.T.
A1  - Ommen, J.R. van
A1  - Denkova, A.G.
T1  - The application of atomic layer deposition in the production of sorbents for ⁹⁹Mo/⁹⁹ᵐTc generator
JF  - Applied Radiation and Isotopes
N2  - New production routes for ⁹⁹Mo are steadily gaining importance. However, the obtained specific activity is much lower than currently produced by the fission of U-235. To be able to supply hospitals with ⁹⁹Mo/⁹⁹ᵐTc generators with the desired activity, the adsorption capacity of the column material should be increased. In this paper we have investigated whether the gas phase coating technique Atomic Layer Deposition (ALD), which can deposit ultra-thin layers on high surface area materials, can be used to attain materials with high adsorption capacity for ⁹⁹Mo. For this purpose, ALD was applied on a silica-core sorbent material to coat it with a thin layer of alumina. This sorbent material shows to have a maximum adsorption capacity of 120 mg/g and has a ⁹⁹ᵐTc elution efficiency of 55 ± 2% based on 3 executive elutions.
Y1  - 2020
U6  - http://dx.doi.org/10.1016/j.apradiso.2020.109266
SN  - 0969-8043
VL  - 164
IS  - 109266
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Frohberg, Martin G.
A1  - Anik, Sabri
T1  - The application of a quadi-chemical lattice model to binary metallic solvents containing oxygen in higher concentrations
JF  - Zeitschrift für Metallkunde
Y1  - 1983
SN  - 0044-3093
VL  - 74
IS  - 10
SP  - 665
EP  - 666
ER  - 
TY  - JOUR
A1  - Waldvogel, Janice
A1  - Ritzmann, Ramona
A1  - Freyler, Kathrin
A1  - Helm, Michael
A1  - Monti, Elena
A1  - Albracht, Kirsten
A1  - Stäudle, Benjamin
A1  - Gollhofer, Albert
A1  - Narici, Marco
T1  - The Anticipation of Gravity in Human Ballistic Movement
JF  - Frontiers in Physiology
N2  - Stretch-shortening type actions are characterized by lengthening of the pre-activated muscle-tendon unit (MTU) in the eccentric phase immediately followed by muscle shortening. Under 1 g, pre-activity before and muscle activity after ground contact, scale muscle stiffness, which is crucial for the recoil properties of the MTU in the subsequent push-off. This study aimed to examine the neuro-mechanical coupling of the stretch-shortening cycle in response to gravity levels ranging from 0.1 to 2 g. During parabolic flights, 17 subjects performed drop jumps while electromyography (EMG) of the lower limb muscles was combined with ultrasound images of the gastrocnemius medialis, 2D kinematics and kinetics to depict changes in energy management and performance. Neuro-mechanical coupling in 1 g was characterized by high magnitudes of pre-activity and eccentric muscle activity allowing an isometric muscle behavior during ground contact. EMG during pre-activity and the concentric phase systematically increased from 0.1 to 1 g. Below 1 g the EMG in the eccentric phase was diminished, leading to muscle lengthening and reduced MTU stretches. Kinetic energy at take-off and performance were decreased compared to 1 g. Above 1 g, reduced EMG in the eccentric phase was accompanied by large MTU and muscle stretch, increased joint flexion amplitudes, energy loss and reduced performance. The energy outcome function established by linear mixed model reveals that the central nervous system regulates the extensor muscles phase- and load-specifically. In conclusion, neuro-mechanical coupling appears to be optimized in 1 g. Below 1 g, the energy outcome is compromised by reduced muscle stiffness. Above 1 g, loading progressively induces muscle lengthening, thus facilitating energy dissipation.
Y1  - 2021
U6  - http://dx.doi.org/10.3389/fphys.2021.614060
SN  - 1664-042X
PB  - Frontiers
CY  - Lausanne
ER  - 
TY  - JOUR
A1  - Förster, Arnold
A1  - Spitzer, A.
A1  - Lüth, H.
T1  - The adsorption of fluor-carbon complexes on GaAs(110) studied by electron energy loss spectroscopy
JF  - Surface Science. 172 (1986), H. 1
Y1  - 1986
SN  - 0039-6028
N1  - ISSN der E-Ausg.: 0039-6028
SP  - 174
EP  - 182
ER  - 
TY  - JOUR
A1  - Knobe, M.
A1  - Giesen, M.
A1  - Plate, S.
A1  - Gradl-Dietsch, G.
A1  - Buecking, B.
A1  - Eschbach, D.
A1  - Laack, Walter van
A1  - Pape, H.-C.
T1  - The Aachen mobility and balance index to measure physiological falls risk: a comparison with the Tinetti POMA scale
JF  - European Journal Of Trauma And Emergency Surgery
N2  - Purpose
The most commonly used mobility assessments for screening risk of falls among older adults are rating scales such as the Tinetti performance oriented mobility assessment (POMA). However, its correlation with falls is not always predictable and disadvantages of the scale include difficulty to assess many of the items on a 3-point scale and poor specificity. The purpose of this study was to describe the ability of the new Aachen Mobility and Balance Index (AMBI) to discriminate between subjects with a fall history and subjects without such events in comparison to the Tinetti POMA Scale.

Methods
For this prospective cohort study, 24 participants in the study group and 10 in the control group were selected from a population of patients in our hospital who had met the stringent inclusion criteria. Both groups completed the Tinetti POMA Scale (gait and balance component) and the AMBI (tandem stance, tandem walk, ten-meter-walk-test, sit-to-stand with five repetitions, 360° turns, timed-up-and-go-test and measurement of the dominant hand grip strength). A history of falls and hospitalization in the past year were evaluated retrospectively. The relationships among the mobility tests were examined with Bland–Altmananalysis. Receiver-operated characteristics curves, sensitivity and specificity were calculated.

Results
The study showed a strong negative correlation between the AMBI (17 points max., highest fall risk) and Tinetti POMA Scale (28 points max., lowest fall risk; r = −0.78, p < 0.001) with an excellent discrimination between community-dwelling older people and a younger control group. However, there were no differences in any of the mobility and balance measurements between participants with and without a fall history with equal characteristics in test comparison (AMBI vs. Tinetti POMA Scale: AUC 0.570 vs. 0.598; p = 0.762). The Tinetti POMA Scale (cut-off <20 points) showed a sensitivity of 0.45 and a specificity of 0.69, the AMBI a sensitivity of 0.64 and a specificity of 0.46 (cut-off >5 points).

Conclusion
The AMBI comprises mobility and balance tasks with increasing difficulty as well as a measurement of the dominant hand-grip strength. Its ability to identify fallers was comparable to the Tinetti POMA Scale. However, both measurement sets showed shortcomings in discrimination between fallers and non-fallers based on a self-reported retrospective falls-status.
KW  - Tinetti test
KW  - Mobility
KW  - Mobility tests
KW  - Ground-level falls
KW  - Elderly
KW  - Fall prevention
KW  - Co-managed care
KW  - Balance
Y1  - 2016
U6  - http://dx.doi.org/10.1007/s00068-016-0693-2
SN  - 1863-9941
VL  - 42
IS  - 5
SP  - 537
EP  - 545
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Hoyler, Friedrich
A1  - Drissi, S.
A1  - Tercier, P. A.
T1  - The 112Cd laboratory - An extension :  EO strengths, multiphonon states and coupled vibrations / S. Drissi ; P. A. Tercier ... F. Hoyler ...
JF  - Nuclear physics <Amsterdam> / A. 614 (1997), H. 2
Y1  - 1997
SN  - 0375-9474
SP  - 137
EP  - 182
ER  - 
TY  - JOUR
A1  - Scholl, Ingrid
A1  - Pelikan, Erich
A1  - Repges, Rudolf
A1  - Tolxdorff, Thomas
T1  - Texture-based feature extraction using the Wavelet transform on x rays.
JF  - Medical Imaging 1996: Image Processing
Y1  - 1996
N1  - Proceedings of SPIE 2710
SP  - 668
EP  - 678
ER  - 
TY  - JOUR
A1  - Mühl, Thomas
A1  - Obolenski, B.
T1  - Textilien und elektromagnetische Strahlung
JF  - Melliand-Textilberichte. 85 (2004), H. 3
Y1  - 2004
SN  - 0341-0781
SP  - 190
EP  - 192
ER  - 
TY  - JOUR
A1  - Gerhardt, Hans Joachim
T1  - Teures Bauen durch starre Genehmigungspraxis
JF  - Der Bausachverständige : Zeitschrift für Bauschäden, Grundstückswert und gutachterliche Tätigkeit. 1 (2005), H. 5
Y1  - 2005
SN  - 1614-6123
SP  - 44
EP  - 45
ER  - 
TY  - JOUR
A1  - Jeromin, Günter Erich
T1  - Tetrabenzo[a,c,h,j]phenoxazine-18-yl a new stable neutral radical
JF  - Tetrahedron Letters  . 42 (2001), H. 10
Y1  - 2001
SN  - 0040-4039
N1  - ISSN der E-Ausg.: 1359-8562
SP  - 1863
EP  - 1865
ER  - 
TY  - JOUR
A1  - Schwarzer, Klemens
A1  - Faber, C.
A1  - Stracke, T.
T1  - Teststelle fuer Warmwasser-Kollektoren und -Systeme
JF  - Energiewirtschaftliche Tagesfragen. 44 (1994), H. 9
Y1  - 1994
SN  - 0720-6240
N1  - Zusammenarbeit mit dem tunesischen Forschungsinstitut INRST
SP  - 41
EP  - 43
ER  - 
TY  - JOUR
A1  - Schwarzer, Klemens
A1  - Stracke, Thomas
T1  - Teststand für solarthermische Kollektoren
JF  - Energie für die Zukunft : 28. Juni bis 1. Juli 1994 ; [Tagungsbericht 1] / 9. Internationales Sonnenforum '94. [Hrsg. Deutsche Gesellschaft für Sonnenenergie e.V. - DGS. Red. A. Hohmann ; H. H. Hohmann].  - (Internationales Sonnenforum ; 9,1)
Y1  - 1994
N1  - Internationales Sonnenforum <9, 1994, Stuttgart> ; Deutsche Gesellschaft für Sonnenenergie
SP  - 319
EP  - 326
PB  - DGS-Sonnenenergie
CY  - München
ER  - 
TY  - JOUR
A1  - Schwarzer, Klemens
A1  - Bieger, W.
T1  - Tests von solaren Brauchwassersystemen / W. Bieger ; K. Schwarzer
JF  - Erneuerbare Energiequellen : Aktivitäten deutscher Hochschulen / zsgest. von F. A. Peuser ...
Y1  - 1987
SP  - 6
EP  - 7
PB  - Zentralstelle für Solartechnik
CY  - Hilden
ER  - 
TY  - JOUR
A1  - Samm, Doris
A1  - Bosetti, P.-C.
T1  - Testmessungen an einem grossflaechigen (Durchmesser 35 cm) Photomultiplier Test measurements of a large-area (diameter 35 cm) photomultiplier / Bosetti, P.-C.; ... Samm, D. [u.a.]
JF  - Verhandlungen der Deutschen Physikalischen Gesellschaft. 25 (1990), H. 1
Y1  - 1990
N1  - Fruehjahrstagung des Fachausschusses Teilchenphysik der Deutschen Physikalischen Gesellschaft e.V. (DPG), Hamburg (Germany), 21-24 Mar 1990
SP  - 33
EP  - 33
ER  - 
TY  - JOUR
A1  - Robinson, A. E.
A1  - Rönna, Uwe
A1  - Funke, Harald
T1  - Testing of a 10 kW diffusive micro-mix combustor for hydrogen-fuelled micro-scale gas turbines
JF  - International Workshop on Micro and Nanotechnology for Power Generation and Energy Conversion Applications <7, 2007, Freiburg, Breisgau>  ; PowerMEMS ; 7
Y1  - 2007
SP  - 225
EP  - 228
ER  - 
TY  - JOUR
A1  - Gaigall, Daniel
T1  - Testing marginal homogeneity of a continuous bivariate distribution with possibly incomplete paired data
JF  - Metrika
N2  - We discuss the testing problem of homogeneity of the marginal distributions of a continuous bivariate distribution based on a paired sample with possibly missing components (missing completely at random). Applying the well-known two-sample Crámer–von-Mises distance to the remaining data, we determine the limiting null distribution of our test statistic in this situation. It is seen that a new resampling approach is appropriate for the approximation of the unknown null distribution. We prove that the resulting test asymptotically reaches the significance level and is consistent. Properties of the test under local alternatives are pointed out as well. Simulations investigate the quality of the approximation and the power of the new approach in the finite sample case. As an illustration we apply the test to real data sets.
KW  - Marginal homogeneity test
KW  - Crámer–von-Mises distance
KW  - Paired sample
KW  - Incomplete data
KW  - Resampling test
Y1  - 2019
U6  - http://dx.doi.org/10.1007/s00184-019-00742-5
SN  - 1435-926X
VL  - 2020
IS  - 83
SP  - 437
EP  - 465
PB  - Springer
ER  - 
TY  - JOUR
A1  - Ditzhaus, Marc
A1  - Gaigall, Daniel
T1  - Testing marginal homogeneity in Hilbert spaces with applications to stock market returns
JF  - Test
N2  - This paper considers a paired data framework and discusses the question of marginal homogeneity of bivariate high-dimensional or functional data. The related testing problem can be endowed into a more general setting for paired random variables taking values in a general Hilbert space. To address this problem, a Cramér–von-Mises type test statistic is applied and a bootstrap procedure is suggested to obtain critical values and finally a consistent test. The desired properties of a bootstrap test can be derived that are asymptotic exactness under the null hypothesis and consistency under alternatives. Simulations show the quality of the test in the finite sample case. A possible application is the comparison of two possibly dependent stock market returns based on functional data. The approach is demonstrated based on historical data for different stock market indices.
Y1  - 2022
U6  - http://dx.doi.org/10.1007/s11749-022-00802-5
SN  - 1863-8260
VL  - 2022
IS  - 31
SP  - 749
EP  - 770
PB  - Springer
ER  - 
TY  - JOUR
A1  - Bécret, P.
A1  - Grossen, J.
A1  - Trilla, J.
A1  - Robinson, A.
A1  - Bosschaerts, W.
A1  - Funke, Harald
A1  - Hendrick, P.
T1  - Testing and numerical study of a 10 kW hydrogen micro combustor
JF  - International Workshop on Micro and Nanotechnology for Power Generation and Energy Conversion Applications <7, 2007, Freiburg, Breisgau>  ; PowerMEMS ; 7
Y1  - 2007
SP  - 367
EP  - 370
ER  - 
TY  - JOUR
A1  - Heinke, Lars N.
A1  - Knicker, Axel J.
A1  - Albracht, Kirsten
T1  - Test-retest reliability of the internal shoulder rotator muscles' stretch reflex in healthy men
JF  - Journal of Electromyography and Kinesiology
N2  - Until now the reproducibility of the short latency stretch reflex of the internal rotator muscles of the glenohumeral joint has not been identified. Twenty-three healthy male participants performed three sets of external shoulder rotation stretches with various pre-activation levels on two different dates of measurement to assess test-retest reliability. All stretches were applied with a dynamometer acceleration of 104°/s2 and a velocity of 150°/s. Electromyographical response was measured via surface EMG. Reflex latencies showed a pre-activation effect (ƞ2 = 0,355). ICC ranged from 0,735 to 0,909 indicating an overall “good” relative reliability. SRD 95% lay between ±7,0 to ±12,3 ms.. The reflex gain showed overall poor test-retest reproducibility. The chosen methodological approach presented a suitable test protocol for shoulder muscles stretch reflex latency evaluation. A proof-of-concept study to validate the presented methodical approach in shoulder involvement including subjects with clinically relevant conditions is recommended.
KW  - stretch reflex
KW  - shoulder
KW  - test-retest reliability
KW  - intraclass correlation coefficient
KW  - standard error of measurement
Y1  - 2021
U6  - http://dx.doi.org/10.1016/j.jelekin.2021.102611
SN  - 1050-6411
VL  - 62
IS  - Article 102611
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Hillen, Walter
T1  - Test of QED in e+e&#8722; annihilation at energies between 12 and 31.6 GeV. TASSO Collaboration
JF  - Physics Letters B. 94 (1980), H. 2
Y1  - 1980
SN  - 0370-2693
SP  - 259
EP  - 265
ER  - 
TY  - JOUR
A1  - Gaigall, Daniel
T1  - Test for Changes in the Modeled Solvency Capital Requirement of an Internal Risk Model
JF  - ASTIN Bulletin
N2  - In the context of the Solvency II directive, the operation of an internal risk model is a possible way for risk assessment and for the determination of the solvency capital requirement of an insurance company in the European Union. A Monte Carlo procedure is customary to generate a model output. To be compliant with the directive, validation of the internal risk model is conducted on the basis of the model output. For this purpose, we suggest a new test for checking whether there is a significant change in the modeled solvency capital requirement. Asymptotic properties of the test statistic are investigated and a bootstrap approximation is justified. A simulation study investigates the performance of the test in the finite sample case and confirms the theoretical results. The internal risk model and the application of the test is illustrated in a simplified example. The method has more general usage for inference of a broad class of law-invariant and coherent risk measures on the basis of a paired sample.
KW  - Bootstrap
KW  - Empirical process
KW  - Functional Delta Method
KW  - Hadamard differentiability
KW  - Paired sample
Y1  - 2021
U6  - http://dx.doi.org/10.1017/asb.2021.20
SN  - 1783-1350
VL  - 51
IS  - 3
SP  - 813
EP  - 837
PB  - Cambridge Univ. Press
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Geimer, Konstantin
A1  - Sauerborn, Markus
A1  - Hoffschmidt, Bernhard
A1  - Schmitz, Mark
A1  - Göttsche, Joachim
T1  - Test Facility for Absorber Specimens of Solar Tower Power Plants
JF  - Advances in Science and Technology. 74 (2010)
Y1  - 2010
N1  - 5th Forum on New Materials : CIMTEC 2010, Montecatini Terme, Italy 13-18 June 2010. Part C
SP  - 266
EP  - 271
ER  - 
TY  - JOUR
A1  - Müller-Veggian, Mattea
A1  - Cesari, V.
A1  - Conte, V.
A1  - De Nardo, L.
T1  - TEPCs working at nanometre level
JF  - Annual report / Istituto Nazionale di Fisica Nucleare, LNL, Laboratori Nazionali di Legnaro. 1999 (2000)
Y1  - 2000
N1  - LNL-INFN(REP)-160/2000
SP  - 117
ER  - 
TY  - JOUR
A1  - Laack, Walter van
T1  - Tennisarm - Ursachen und Behandlung
JF  - Apotheker-Journal . 9 (1987), H. 2
Y1  - 1987
SN  - 0720-1028
SP  - 42
ER  - 
TY  - JOUR
A1  - Frings, Michael
T1  - Tendenzwende in der Rechtsprechung zur Anwendung des HWiG auf Angehörige
JF  - Verbraucher und Recht : VuR (1997)
Y1  - 1997
SN  - 0930-8369
SP  - 201
EP  - 205
ER  - 
TY  - JOUR
A1  - Mohnke, Andreas
A1  - Schuckel, G.
T1  - Tempern von Oberflächenwellenwandlern in Schichtstruktur
JF  - Technische Hochschule Ilmenau / Bibliothek: Wissenschaftliche Zeitschrift. 32 (1986), H. 3
Y1  - 1986
SN  - 0043-6917
SP  - 151
EP  - 160
ER  - 
TY  - JOUR
A1  - Nomdedeu, Mar Monsonis
A1  - Willen, Christine
A1  - Schieffer, Andre
A1  - Arndt, Hartmut
T1  - Temperature-dependent ranges of coexistence in a model of a two-prey-one-predator microbial food web
JF  - Marine Biology
N2  - The objective of our study was to analyze the effects of temperature on the population dynamics of a three-species food web consisting of two prey bacteria (Pedobacter sp. and Acinetobacter johnsonii) and a protozoan predator (Tetrahymena pyriformis) as model organisms. We assessed the effects of temperature on the growth rates of all three species with the objective of developing a model with four differential equations based on the experimental data. The following hypotheses were tested at a theoretical level: Firstly, temperature changes can affect the dynamic behavior of a system by temperature-dependent parameters and interactions and secondly, food web response to temperature cannot be derived from the single species temperature response. The main outcome of the study is that temperature changes affect the parameter range where coexistence is possible within all three species. This has significant consequences on our ideas regarding the evaluation of effects of global warming.
Y1  - 2012
U6  - http://dx.doi.org/10.1007/s00227-012-1966-x
SN  - 1432-1793
VL  - 159
IS  - 11
SP  - 2423
EP  - 2430
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Kelemen, Christina
A1  - Porst, Dariusz
A1  - Büldt, G. [u.a.]
T1  - Temperature transitions of protein properties in human red blood cells. Artmann, Gerhard Michael, Kelemen, Christina; Porst, D.; Büldt, G.; Chien, S.
JF  - Biophysical Journal. 75 (1998), H. 6
Y1  - 1998
SN  - 1542-0086
N1  - http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=1299989&blobtype=pdf
SP  - 3179
EP  - 3183
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Kelemen, C.
A1  - Chien, S.
T1  - Temperature transition of human hemoglobin at body temperature: effects of calcium. Kelemen, C.; Chien, S.; Artmann, Gerhard Michael
JF  - Biophysical journal. 80 (2001), H. 6
Y1  - 2001
SN  - 1542-0086
SP  - 2622
EP  - 2630
ER  - 
TY  - JOUR
A1  - Bohn, D.
A1  - Funke, Harald
A1  - Gier, J.
T1  - Temperature jet development in a cross-over channel
JF  - Third European Conference on Turbomachinery - fluid dynamics and thermodynamics : : 2 - 5 March 1999, Royal National Hotel, London, UK / organized by the Energy Transfer and Thermofluid Mechanics Group of the Institution of Mechanical Engineers (IMechE); with support and sponsorship from European Commission / Vol. B.
Y1  - 1999
N1  - C557/158/99 ; IMechE conference transactions 1999-1B
SP  - 671
EP  - 680
PB  - Professional Engineering Publ.
CY  - Bury St. Edmunds
ER  - 
TY  - JOUR
A1  - Seefeldt, Patric
A1  - Dachwald, Bernd
T1  - Temperature increase on folded solar sail membranes
JF  - Advances in Space Research
Y1  - 2021
U6  - http://dx.doi.org/10.1016/j.asr.2020.09.026
SN  - 0273-1177
VL  - 67
IS  - 9
SP  - 2688
EP  - 2695
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Mottaghy, Darius
A1  - Vosteen, Hans-Dieter
A1  - Schellschmidt, Rüdiger
T1  - Temperature dependence of the relationship of thermal diffusivity versus thermal conductivity for crystalline rocks
JF  - International Journal of Earth Sciences
Y1  - 2008
U6  - http://dx.doi.org/10.1007/s00531-007-0238-3
SN  - 1437-3262
VL  - 97
IS  - 2
SP  - 435
EP  - 442
ER  - 
TY  - JOUR
A1  - Kämper, Klaus-Peter
A1  - Schmitt, W.
A1  - Güntherodt, G.
T1  - Temperature dependence of the exchange splitting of Ni along the &#61511;-L line
JF  - Journal de physique. 49 (1988), H. 12. Supplement, Colloque C8
Y1  - 1988
N1  - Proceedings of the International conference on Magnetism. Part 1. ICM 88, Paris, France, Juli 25-29, 1988
SP  - 39
EP  - 40
ER  - 
TY  - JOUR
A1  - Kämper, Klaus-Peter
A1  - Schmitt, W.
A1  - Güntherodt, G.
T1  - Temperature and wave-vector dependence of the spin-split band structure of Ni(111) along the &#915;-L line
JF  - Physical Review B. 42 (1990), H. 16
Y1  - 1990
SN  - 1095-3795
SP  - 10696
EP  - 10705
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Stache, O.
A1  - Königsfeld, J.
T1  - Temperaturabhängigkeit der Pseudopodienbildung und Rückbildung von Granulozyten / Stache, O. ; Königsfeld, J. ; Artmann, G. M.
JF  - Biomedizinische Technik = Biomedical Engineering. 45 (2000), H. s1
Y1  - 2000
SN  - 1862-278X
SP  - 450
EP  - 451
ER  - 
TY  - JOUR
A1  - Breitbach, Gerd
A1  - Klomfass, J.
A1  - Hannen, W.
T1  - Temperatur- und Dehnungsmessung an komplex beanspruchten metallischen Bauteilen im Temperaturbereich um 900 C / J. Klomfass ; W. Hannen ; G. Breitbach
JF  - Vorträge der Tagung Werkstoffprüfung 1992 : 3. und 4. Dezember 1992 in Bad Nauheim / DVM, Deutscher Verband für Materialforschung und -prüfung e.V. Veranstaltet von: Deutsche Gesellschaft für Materialkunde ...
Y1  - 1992
N1  - Tagung Werkstoffprüfung <1992, Bad Nauheim> ; Deutsche Gesellschaft für Materialkunde
SP  - 93
EP  - 100
PB  - DVM
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Wittmann, Klaus
A1  - Fortezza, R.
T1  - Telescience opportunities in the precursor flights
JF  - Space Technology - Industrial and Commercial Applications. 13 (1992), H. 2
Y1  - 1992
SN  - 0892-9270
SP  - 221
EP  - 226
ER  - 
TY  - JOUR
A1  - Breitschuh, S.
A1  - Graber, S.
A1  - Hagemann, Hans-Jürgen
A1  - Hemdt, A. vom
A1  - Schmitz, Günter
T1  - Telematiklabore mit LabVIEW in der Ingenieurausbildung
JF  - Virtuelle Instrumente in der Praxis : Messtechnik, Automatisierung ; Begleitband zum Kongress VIP 2003 / Rahman Jamal ; Hans Jaschinski (Hrsg.).
Y1  - 2003
SN  - 3-7785-2908-0
N1  - VIP <2003, München>
SP  - 458
EP  - 464
PB  - Hüthig
CY  - Heidelberg [u.a.]
ER  - 
TY  - JOUR
A1  - Siepmann, Thomas
A1  - Schuh, G.
A1  - Keil, M.
T1  - TELEflow – Eine Methode zum Reengineering von Prozessen in Wertschöpfungsnetzwerken / Schuh, G.; Siepmann, Th.; Keil, M.
JF  - Industrie-Management : Zeitschrift für industrielle Geschäftsprozesse (1997)
Y1  - 1997
SP  - 21
EP  - 24
ER  - 
TY  - JOUR
A1  - Fredebeul-Krein, Markus
T1  - Telecommunications and WTO discipline : an assessment of the WTO agreement on telecommunication services
JF  - Telecommunications policy. 21 (1997), H. 6
Y1  - 1997
SN  - 0308-5961
SP  - 477
EP  - 491
ER  - 
TY  - JOUR
A1  - Delaittre, Guillaume
T1  - Telechelic Poly(2-Oxazoline)s
JF  - European Polymer Journal
Y1  - 2019
U6  - http://dx.doi.org/10.1016/j.eurpolymj.2019.109281
SN  - 0014-3057
IS  - In Press, Journal Pre-proof, 109281
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Olbertz, Klaus
T1  - Teilzeitarbeit - Die verschiedenen Formen sowie deren Voraussetzungen und Rechtsfolgen
JF  - NWB - Steuer- und Wirtschaftsrecht
Y1  - 2018
SN  - 1860-9449
IS  - 43
SP  - 3182
EP  - 3195
PB  - NWB Verlag
CY  - Herne
ER  - 
TY  - JOUR
A1  - Ermelenko, Y.
A1  - Yoshinobu, T.
A1  - Mourzina, Y.
A1  - Furuichi, K.
A1  - Iwasaki, H.
A1  - Vlasov, Y.
A1  - Schöning, Michael Josef
T1  - Technology of photocurable polymeric membranes for integrated LAPS
JF  - Proceedings of the 5th East Asian Conference on Chemical Sensors; the 33rd Chemical Sensor Symposium : December 4 - 7, 2001, Huis Ten Bosch, Sasebo-shi, Nagasaki, Japan / Japan Association of Chemical Sensors; the Electrochemical Society of Japan
Y1  - 2001
N1  - Chemical sensors; 17.2001 Suppl. B; East Asian Conference on Chemical Sensors ; (5, 2001; Nagasaki)
SP  - 66
EP  - 68
PB  - Japan Association of Chemical Sensors
CY  - Kasuga, Fukuoka-ken
ER  - 
TY  - JOUR
A1  - Mourzina, Y.
A1  - Yoshinobu, T.
A1  - Ermelenko, Y.
A1  - Furuichi, K.
A1  - Vlasov, Y.
A1  - Schöning, Michael Josef
A1  - Iwasaki, H.
T1  - Technology of photocurable membranes for ion sensors based on laser scanned semiconductor transducer (LSST)
JF  - Book of abstracts / ed. by J. Saneistr.
Y1  - 2002
SN  - 80-01-02576-4
N1  - Eurosensors ; (16, 2002, Praha)
SP  - 254
EP  - 257
PB  - Czech Technical University, Faculty of Electrical Engineering, Department of Measurement
CY  - Prague
ER  - 
TY  - JOUR
A1  - Thomas, Axel
T1  - Technologiezentren in der Aachener Region – Retrospektiven und Perspektiven
JF  - VM Verwaltung und Management
Y1  - 2018
U6  - http://dx.doi.org/10.5771/0947-9856-2018-3-147
SN  - 0947-9856
VL  - 24
IS  - 3
SP  - 147
EP  - 156
PB  - Nomos
CY  - Baden-Baden
ER  - 
TY  - JOUR
A1  - Puppe, Michael
A1  - Giuliano, Stefano
A1  - Frantz, Cathy
A1  - Uhlig, Ralf
A1  - Schumacher, Ralph
A1  - Ibraheem, Wagdi
A1  - Schmalz, Stefan
A1  - Waldmann, Barbara
A1  - Guder, Christoph
A1  - Peter, Dennis
A1  - Schwager, Christian
A1  - Teixeira Boura, Cristiano José
A1  - Alexopoulos, Spiros
A1  - Spiegel, Michael
A1  - Wortmann, Jürgen
A1  - Hinrichs, Matthias
A1  - Engelhard, Manfred
A1  - Aust, Michael
T1  - Techno-economic optimization of molten salt solar tower plants
JF  - AIP Conference Proceedings art.no. 040033
N2  - In this paper the results of a techno-economic analysis of improved and optimized molten salt solar tower plants (MSSTP plants) are presented. The potential improvements that were analyzed include different receiver designs, different designs of the HTF-system and plant control, increased molten salt temperatures (up to 640°C) and multi-tower systems. Detailed technological and economic models of the solar field, solar receiver and high temperature fluid system (HTF-system) were developed and used to find potential improvements compared to a reference plant based on Solar Two technology and up-to-date cost estimations. The annual yield model calculates the annual outputs and the LCOE of all variants. An improved external tubular receiver and improved HTF-system achieves a significant decrease of LCOE compared to the reference. This is caused by lower receiver cost as well as improvements of the HTF-system and plant operation strategy, significantly reducing the plant own consumption. A novel star receiver shows potential for further cost decrease. The cavity receiver concepts result in higher LCOE due to their high investment cost, despite achieving higher efficiencies. Increased molten salt temperatures seem possible with an adapted, closed loop HTF-system and achieve comparable results to the original improved system (with 565°C) under the given boundary conditions. In this analysis all multi tower systems show lower economic viability compared to single tower systems, caused by high additional cost for piping connections and higher cost of the receivers.
REFERENCES
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IS  - Issue 1
PB  - AIP Publishing
CY  - Melville, NY
ER  - 
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A1  - Helsper, Christoph
A1  - Fißan, H. J.
T1  - Techniken zur Kalibrierung von Staubmeßgeräten / Fißan, H. J.; Helsper, C.
JF  - Schwebstoffe und Stäube : analyt. u. techn. Aspekte ; Kolloquium Nürnberg 1981
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Y1  - 1987
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Y1  - 1991
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SP  - 450
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T1  - Technically Optimal Inspection Policy with Arithmetical Adaption
JF  - IMA Journal of Management Mathematics. 14 (2003), H. 4
Y1  - 2003
SN  - 1471-678X
N1  - weitere ISSN 1471-6798 (E)
SP  - 357
EP  - 371
ER  - 
TY  - JOUR
A1  - Chudoba, Rostislav
A1  - Butenweg, Christoph
A1  - Peiffer, F.
T1  - Technical information system for collaborative material research
JF  - Advances in engineering software
Y1  - 2004
U6  - http://dx.doi.org/10.1016/j.advengsoft.2004.03.021
SN  - 1873-5339 (E-Journal); 0965-9978 (Print)
VL  - Volume 35
IS  - Issue 10-11
SP  - 747
EP  - 756
ER  - 
TY  - JOUR
A1  - Wittmann, Klaus
A1  - Ulamec, S.
A1  - Feuerbacher, B.
A1  - Rosenbauer, H.
T1  - Technical Challenge, Scientific Thrill: A Long Term Lander on an Active Comet
JF  - Lunar and Planetary Science. 26 (1995)
Y1  - 1995
SN  - 0270-9511
N1  - Proceedings of the 26th Lunar and Planetary Science Conference / org. by Lunar and Planetary Institute, Houston Texas
SP  - 1431
EP  - 1432
ER  - 
TY  - JOUR
A1  - Heger, Michael
T1  - Teamtraining für ein Software-Engineering-Praktikum
JF  - Hochschule und lebendiges Lernen : Beispiele für themenzentrierte Interaktion / hrsg. von Gerhard Portele und Michael Heger ...
Y1  - 1995
SN  - 3-89271-595-5
N1  - Blickpunkt Hochschuldidaktik ; 99
SP  - 189
EP  - 203
PB  - Dt. Studien-Verl.
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Grap, Rolf Dietmar
T1  - Team-Check : Optimierung von Gruppenarbeit
JF  - Der Industrie-Meister: Fachzeitschrift für Führung, Technik, Weiterbildung. 28 (1999), H. 11
Y1  - 1999
SN  - 0537-5770 ; 0940-843
SP  - 13
EP  - 16
ER  - 
TY  - JOUR
A1  - Ferrein, Alexander
A1  - Niemüller, Tim
A1  - Steinbauer, Gerald
T1  - Team Zadeat 2010 : application for participation
Y1  - 2010
ER  - 
TY  - JOUR
A1  - Ferrein, Alexander
A1  - Steinbauer, Gerald
A1  - McPhillips, Graeme
A1  - Niemüller, Tim
A1  - Potgieter, Anet
T1  - Team Zadeat 2009 : team report
Y1  - 2009
VL  - 6
SP  - 1
ER  - 
TY  - JOUR
A1  - Maurischat, Andreas
A1  - Perkins, Rudolph
T1  - Taylor coefficients of Anderson generating functions and Drinfeld torsion extensions
N2  - We generalize our work on Carlitz prime power torsion extension to torsion extensions of Drinfeld modules of arbitrary rank. As in the Carlitz case, we give a description of these extensions in terms of evaluations of Anderson generating functions and their hyperderivatives at roots of unity. We also give a direct proof that the image of the Galois representation attached to the p-adic Tate module lies in the p-adic points of the motivic Galois group. This is a generalization of the corresponding result of Chang and Papanikolas for the t-adic case.
Y1  - 2020
U6  - http://dx.doi.org/10.1142/S1793042122500099
IS  - Vol. 18, No. 01
SP  - 113
EP  - 130
PB  - World Scientific
CY  - Singapur
ER  - 
TY  - JOUR
A1  - Hebel, Christoph
T1  - Taxiverkehr in Deutschland
JF  - Stadt Region Land (2008)
Y1  - 2008
SN  - 0344-9645
SP  - 21
EP  - ff
ER  - 
TY  - JOUR
A1  - Heiden, W.
A1  - Turek, M.
A1  - Schöning, Michael Josef
T1  - TasteIT : Analyzing chemical sensor data using fuzzy logic
Y1  - 2011
SN  - 978-1-4244-9910-6
N1  - 2011 IEEE Workshop on Merging Fields of Computational Intelligence and Sensor Technology ; 11.-15. April 2011 Paris, France
SP  - 1
EP  - 6
PB  - IEEE
CY  - New York
ER  - 
TY  - JOUR
A1  - Wolf, Martin
A1  - Foltz, Christian
A1  - Killich, Stephan
A1  - Schmidt, Ludger
T1  - Task and Information Modeling for Cooperative Work / Foltz, Christian ; Killich, Stephan ; Wolf, Martin ; Schmidt, Ludger ; Luczak, Holger
JF  - Systems, social and internationalization design aspects of human-computer interaction / ed. by Michael J. Smith, Gavriel Salvendy  Vol. 2
Y1  - 2001
SN  - 0-8058-3608-X
N1  - International Conference on Human Computer Interaction 9, 2001, New Orleans, La.
SP  - 172
EP  - 176
PB  - -
ER  - 
TY  - JOUR
A1  - Röth, A.A.
A1  - Slabu, I.
A1  - Engelmann, Ulrich M.
A1  - Baumann, M.
A1  - Schmitz-Rode, T.
A1  - Neumann, U. P.
T1  - Targeting von gastroenterologischen Tumoren mittels magnetischer Nanopartikel zur hyperthermischen Therapie
JF  - Zeitschrift für Gastroenterologie
Y1  - 2017
U6  - http://dx.doi.org/10.1055/s-0037-1605124
VL  - 55
IS  - 8
SP  - KV-384
PB  - Thieme
CY  - Stuttgart
ER  - 
TY  - JOUR
A1  - Gossla, Ulrich
T1  - Talbrücke Seßlestal - Stahlverbundbrücke mit einteiligem Querschnitt
JF  - Technik in Bayern (2002)
Y1  - 2002
SP  - 32
EP  - 33
ER  - 
TY  - JOUR
A1  - Prume, Klaus
A1  - Raeder, H.
A1  - Tyholdt, F.
A1  - Booij, W. E.
T1  - Taking piezoelectric microsystems from the laboratory to production  / Raeder, H. ; Tyholdt, F. ; Booij, W. ; Calame, F. ; Ostbo, N. P. ; Bredesen, R. ; Prume, K. ; Rijnders, G. ; Muralt, P.
JF  - Journal of Electroceramics. 19 (2007), H. 4
Y1  - 2007
SN  - 1385-3449
SP  - 357
EP  - 362
ER  - 
TY  - JOUR
A1  - Alt, Helmut
T1  - Tabellenfreie Berechnung der Einkommensteuer mit Hilfe des programmierbaren Taschenrechners
JF  - Elektrizitätswirtschaft
Y1  - 1978
SN  - 0013-5496
VL  - 77
SP  - 486
EP  - 489
PB  - VWEW-Energieverlag
CY  - Frankfurt/Main
ER  - 
TY  - JOUR
A1  - Öhlschläger, Peter
A1  - Michel, Nico
A1  - Osen, Wolfram
A1  - Freyschmidt, Eva-Jasmin
T1  - T cell response to human papillomavirus 16 E7 in mice: comparison of Cr release assay, intracellular IFN-gamma production, ELISPOT and tetramer staining / Michel, Nico ; Öhlschläger, Peter ; Osen, Wolfram ; Freyschmidt, Eva-Jasmin ; Gutöhrlein, Heidrun ;
JF  - Intervirology. 45 (2002)
Y1  - 2002
SN  - 1423-0100
SP  - 290
EP  - 299
ER  - 
TY  - JOUR
A1  - Müller-Veggian, Mattea
A1  - Beuscher, H.
A1  - Gono, Y.
T1  - Systematics of 10⁺ isomers in the N=78 nuclei
JF  - Annual report 1977 / Institut für Kernphysik Kernforschungsanlage Jülich
Y1  - 1978
N1  - Spezielle Berichte der Kernforschungsanlage Jülich ; 15
SP  - 33
EP  - 34
PB  - Verlag des Forschungszentrums Jülich
CY  - Jülich
ER  - 
TY  - JOUR
A1  - Havermann, Marc
T1  - Systematic Shock Tube Experiments on Vortex Ring Generation and Propagation / Havermann, M. ; Kainuma, M. ; Takayama, K.
JF  - Shock waves : proceedings of the 25th International Symposium on Shock Waves-ISSW25, July 17 - 22, 2005, Bangalore, India / ed.: G. Jagadeesh
Y1  - 2006
SN  - 978-81-7371571-6
N1  - International Symposium on Shock Waves ; 25 (Bangalore) : 2005.07.17-22
ISSW ; 25 (Bangalore) : 2005.07.17-22
PB  - Universities Pr.
CY  - Hyderabad
ER  - 
TY  - JOUR
A1  - Fischer, Felix
A1  - Selver, M. Alper
A1  - Gezer, Sinem
A1  - Dicle, Oguz
A1  - Hillen, Walter
T1  - Systematic Parameterization, Storage, and Representation of Volumetric DICOM Data
JF  - Journal of Medical and Biological Engineering
Y1  - 2015
U6  - http://dx.doi.org/10.1007/s40846-015-0097-5
SN  - 2199-4757
VL  - 35
IS  - 6
SP  - 709
EP  - 723
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Müller-Veggian, Mattea
A1  - Beuscher, H.
A1  - Gono, Y.
A1  - Lieder, R. M.
T1  - Systematic features of isomeric states in Ce, Sm, Nd nuclei
JF  - Frühjahrstagung ... des Fachausschusses Kernphysik und Hochenergiephysik der DPG (Sektion A: Kernphysik) / Deutsche Physikalische Gesellschaft (1977)
Y1  - 1977
SP  - 892
ER  - 
TY  - JOUR
A1  - Fissabre, Anke
A1  - Niethammer, Bernhard
T1  - System mit Hülle - Die innovativen Bauten der Steiff-Spielwarenfabrik in Giengen an der Brenz
JF  - In situ : Zeitschrift für Architekturgeschichte
Y1  - 2015
SN  - 1866-959X
N1  - gedruckt in der Bibliothek Bayernallee unter der Signatur 13 Z 959-2015
VL  - 7
IS  - 2
SP  - 247
EP  - 262
PB  - Wernersche Verlagsgesellschaft
CY  - Worms
ER  - 
TY  - JOUR
A1  - Elsen, Ingo
A1  - Kraiss, Karl-Friedrich
T1  - System concept and realization of a scalable neurocomputing architecture
JF  - Systems Analysis Modelling Simulation
N2  - This paper describes the realization of a novel neurocomputer which is based on the concepts of a coprocessor. In contrast to existing neurocomputers the main interest was the realization of a scalable, flexible system, which is capable of computing neural networks of arbitrary topology and scale, with full independence of special hardware from the software's point of view. On the other hand, computational power should be added, whenever needed and flexibly adapted to the requirements of the application. Hardware independence is achieved by a run time system which is capable of using all available computing power, including multiple host CPUs and an arbitrary number of neural coprocessors autonomously. The realization of arbitrary neural topologies is provided through the implementation of the elementary operations which can be found in most neural topologies.
Y1  - 1999
SN  - 0232-9298
SN  - 1029-4902
VL  - 35
IS  - 4
SP  - 399
EP  - 419
PB  - Gordon and Breach Science Publishers
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Turlybekuly, Amanzhol
A1  - Pogrebnjak, Alexander
A1  - Sukhodub, L. F.
A1  - Sukhodub, Liudmyla B.
A1  - Kistaubayeva, A. S.
A1  - Savitskaya, Irina
A1  - Shokatayeva, D. H.
A1  - Bondar, Oleksandr V.
A1  - Shaimardanov, Z. K.
A1  - Plotnikov, Sergey V.
A1  - Shaimardanova, B. H.
A1  - Digel, Ilya
T1  - Synthesis, characterization, in vitro biocompatibility and antibacterial properties study of nanocomposite materials based on hydroxyapatite-biphasic ZnO micro- and nanoparticles embedded in Alginate matrix
JF  - Materials Science and Engineering C
Y1  - 2019
U6  - http://dx.doi.org/10.1016/j.msec.2019.109965
VL  - 104
IS  - Article number 109965
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Paulßen, Elisabeth
A1  - Alberto, Roger
A1  - Abram, Ulrich
T1  - Synthesis, Characterization, and Structures of R3EOTcO3 Complexes (E = C, Si, Ge, Sn, Pb) and Related Compounds
JF  - Inorganic Chemistry
N2  - AgTcO4 reacts with R3ECl compounds (E = C, Si, Ge, Sn, Pb; R = Me, iPr, tBu, Ph), tBu2SnCl2, or PhMgCl under formation of novel trioxotechnetium(VII) derivatives. The carbon and silicon derivatives readily undergo decomposition, which was proven by 99Tc NMR spectroscopy and the isolation of decomposition products such as [TcOCl3(THF)(OH2)]. Compounds [Ph3GeOTcO3], [(THF)Ph3SnOTcO3], [(O3TcO)SntBu2(OH)]2, and [(THF)4Mg(OTcO3)2] are more stable and were isolated in crystalline form and characterized by X-ray diffraction.
Y1  - 2010
U6  - http://dx.doi.org/10.1021/ic1001094
SN  - 1520-510X
VL  - 49
IS  - 7
SP  - 3525
EP  - 3530
PB  - American Chemical Society
CY  - Washington
ER  - 
TY  - JOUR
A1  - Muschallik, Lukas
A1  - Kipp, Carina Ronja
A1  - Recker, Inga
A1  - Bongaerts, Johannes
A1  - Pohl, Martina
A1  - Gelissen, Melanie
A1  - Schöning, Michael Josef
A1  - Selmer, Thorsten
A1  - Siegert, Petra
T1  - Synthesis of α-hydroxy ketones and vicinal diols with the Bacillus licheniformis DSM 13T butane-2, 3-diol dehydrogenase
JF  - Journal of Biotechnology
N2  - The enantioselective synthesis of α-hydroxy ketones and vicinal diols is an intriguing field because of the broad applicability of these molecules. Although, butandiol dehydrogenases are known to play a key role in the production of 2,3-butandiol, their potential as biocatalysts is still not well studied. Here, we investigate the biocatalytic properties of the meso-butanediol dehydrogenase from Bacillus licheniformis DSM 13T (BlBDH). The encoding gene was cloned with an N-terminal StrepII-tag and recombinantly overexpressed in E. coli. BlBDH is highly active towards several non-physiological diketones and α-hydroxyketones with varying aliphatic chain lengths or even containing phenyl moieties. By adjusting the reaction parameters in biotransformations the formation of either the α-hydroxyketone intermediate or the diol can be controlled.
Y1  - 2020
SN  - 2590-1559
U6  - http://dx.doi.org/10.1016/j.jbiotec.2020.09.016
VL  - 202
IS  - Vol. 324
SP  - 61
EP  - 70
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Muschallik, Lukas
A1  - Molinnus, Denise
A1  - Jablonski, Melanie
A1  - Kipp, Carina Ronja
A1  - Bongaerts, Johannes
A1  - Pohl, Martina
A1  - Wagner, Torsten
A1  - Schöning, Michael Josef
A1  - Selmer, Thorsten
A1  - Siegert, Petra
T1  - Synthesis of α-hydroxy ketones and vicinal (R, R)-diols by Bacillus clausii DSM 8716ᵀ butanediol dehydrogenase
JF  - RSC Advances
N2  - α-hydroxy ketones (HK) and 1,2-diols are important building blocks for fine chemical synthesis. Here, we describe the R-selective 2,3-butanediol dehydrogenase from B. clausii DSM 8716ᵀ (BcBDH) that belongs to the metal-dependent medium chain dehydrogenases/reductases family (MDR) and catalyzes the selective asymmetric reduction of prochiral 1,2-diketones to the corresponding HK and, in some cases, the reduction of the same to the corresponding 1,2-diols. Aliphatic diketones, like 2,3-pentanedione, 2,3-hexanedione, 5-methyl-2,3-hexanedione, 3,4-hexanedione and 2,3-heptanedione are well transformed. In addition, surprisingly alkyl phenyl dicarbonyls, like 2-hydroxy-1-phenylpropan-1-one and phenylglyoxal are accepted, whereas their derivatives with two phenyl groups are not substrates. Supplementation of Mn²⁺ (1 mM) increases BcBDH's activity in biotransformations. Furthermore, the biocatalytic reduction of 5-methyl-2,3-hexanedione to mainly 5-methyl-3-hydroxy-2-hexanone with only small amounts of 5-methyl-2-hydroxy-3-hexanone within an enzyme membrane reactor is demonstrated.
Y1  - 2020
U6  - http://dx.doi.org/10.1039/D0RA02066D
SN  - 2046-2069
VL  - 10
SP  - 12206
EP  - 12216
PB  - Royal Society of Chemistry (RSC)
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Heinze, Daniel
A1  - Mang, Thomas
A1  - Peter, Karin
A1  - Möller, Martin
A1  - Weichold, Oliver
T1  - Synthesis of low molecular weight poly(vinyl acetate) and its application as plasticizer
JF  - Journal of applied polymer science
N2  - Poly(vinyl acetate), PVAc, with a degree of polymerization Xn = 10 was prepared by chain-transfer radical polymerization using carbon tetrachloride and used as oligomeric plasticizer for commercial PVAc. However, the chlorinated chain ends cause a low thermal stability requiring mild Cl/H substitution. The product exhibits high thermal stability and excellent melt-compounding properties. Blends of oligomeric and commercial PVAc show single glass transition temperatures which decrease with higher oligomer content and exhibit small negative deviations from Fox' linear additivity rule. This indicates plasticization and miscibility being mainly due to entropic effects. Injection-moulded thick specimens show ductile behaviour at oligomer contents >10 wt %, while sheets with a thickness of 0.2–0.5 mm appear flexible already at 7.5 wt %. The oxygen permeability coefficients are an order of magnitude lower than those of low-density polyethylene. Due to the sum of their properties, the plasticized sheets present a promising alternative in the preparation of barrier materials.
Y1  - 2014
U6  - http://dx.doi.org/10.1002/app.40226
SN  - 1097-4628 (E-Journal); 0021-8995 (Print)
VL  - 131
IS  - 9
SP  - Article No. 40226
PB  - Wiley
CY  - New York
ER  - 
TY  - JOUR
A1  - Nokihara, Kiyoshi
A1  - Berndt, Heinz
T1  - Synthesis of hapten–polypeptide conjugates as antigen models for the N-terminal region of the α-2-chain of rabbit skin collagen
JF  - Journal of the Royal Society of Chemistry: Perkin Transactions 1
N2  - Synthesis of derivatives of the peptide sequence L-pyroglutamyl-L-phenylalanyl-L-aspartyl-glycyl-L-lysyl-glycyl-glycyl-glycine as the antigenic determinant representing the N-terminal non-helical region of the α-2-chain of rabbit skin collagen, and conjugation to two different polypeptide carriers, are described.
Y1  - 1978
U6  - http://dx.doi.org/10.1039/P19780000260
SN  - 1364-5463
SN  - 0300-922X
SN  - 1470-4358
VL  - 1978
IS  - 3
SP  - 260
EP  - 263
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Immel, Timo
A1  - Grützke, Martin
A1  - Späte, Anne-Katrin
A1  - Groth, Ulrich
A1  - Öhlschläger, Peter
A1  - Huhn, Thomas
T1  - Synthesis and X-ray structure analysis of a heptacoordinate titanium(IV)-bis-chelate with enhanced in vivo antitumor efficacy
JF  - Chemical Communications
N2  - Chelate stabilization of a titanium(IV)–salan alkoxide by ligand exchange with 2,6-pyridinedicarboxylic acid (dipic) resulted in heptacoordinate complex 3 which is not redox-active, stable on silica gel and has increased aqueous stability. 3 is highly toxic in HeLa S3 and Hep G2 and has enhanced antitumor efficacy in a mouse cervical-cancer model.
Y1  - 2012
U6  - http://dx.doi.org/10.1039/C2CC31624B
SN  - 1364-548X
VL  - 48
IS  - 46
SP  - 5790
EP  - 5792
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Pellegrini, Paul A.
A1  - Howell, Nicholas R.
A1  - Shepherd, Rachael K.
A1  - Lengkeek, Nigel A.
A1  - Paulßen, Elisabeth
A1  - Katsifis, Andrew G.
A1  - Greguric, Ivan
T1  - Synthesis and Radiolabelling of DOTA-Linked Glutamine Analogues with 67,68Ga as Markers for Increased Glutamine Metabolism in Tumour Cells
JF  - Molecules
Y1  - 2013
U6  - http://dx.doi.org/10.3390/molecules18067160
SN  - 1420-3049
VL  - 18
IS  - 6
SP  - 7160
EP  - 7178
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Meyer-Stork, L. Sebastian
A1  - Höcker, Hartwig
A1  - Berndt, Heinz
T1  - Syntheses and reactions of urethanes of cellobiose and cellulose-containing uretdione groups
JF  - Journal of applied polymer science
Y1  - 1992
SN  - 1097-4628
VL  - 44
IS  - 6
SP  - 1043
EP  - 1049
ER  - 
TY  - JOUR
A1  - Wolf, Wilhelm
A1  - Berndt, Heinz
A1  - Brandenburg, Dietrich
T1  - Synthese von Fragmenten einer [LysA13] Rinder-Insulin-A-Kette unter Verwendung des S-tert-Butylmercaptorestes als Thiolschutz
JF  - Hoppe-Seyler's Zeitschrift für physiologische Chemie
Y1  - 1979
U6  - http://dx.doi.org/10.1515/bchm2.1979.360.2.1549
SN  - 1437-4315
SN  - 0018-4888
VL  - 360
IS  - 2
SP  - 1549
EP  - 1558
ER  - 
TY  - JOUR
A1  - Berndt, Heinz
T1  - Synthese der Sequenz 71—86 des Humanproinsulins, III : Synthese über die Fragmente 71—78 und 79—86
JF  - Hoppe-Seyler's Zeitschrift für physiologische Chemie
Y1  - 1979
U6  - http://dx.doi.org/10.1515/bchm2.1979.360.1.765
SN  - 1437-4315
SN  - 0018-4888
VL  - 360
IS  - 1
SP  - 765
EP  - 772
ER  - 
TY  - JOUR
A1  - Berndt, Heinz
T1  - Synthese der Sequenz 71—86 des Humanproinsulins, I : Synthese der Sequenz 71—86 als monomeres cyclisches Biscystinpeptidderivat und als Tetra-S-tritylderivat
JF  - Hoppe-Seyler's Zeitschrift für physiologische Chemie
Y1  - 1979
U6  - http://dx.doi.org/10.1515/bchm2.1979.360.1.747
SN  - 1437-4315
SN  - 0018-4888
VL  - 360
IS  - 1
SP  - 747
EP  - 760
ER  - 
TY  - JOUR
A1  - Gielen, Hans-Günther
A1  - Wolf, Günter
A1  - Berndt, Heinz
A1  - Zahn, Helmut
T1  - Synthese der Fragmente A1–8, A9–15 und A16–21 der Schafinsulin-A-Kette unter Verwendung des S-tert-Butylmercaptorestes als Thiolschutzgruppe
JF  - Hoppe-Seyler's Zeitschrift für physiologische Chemie
Y1  - 1979
U6  - http://dx.doi.org/10.1515/bchm2.1979.360.2.1535
SN  - 1437-4315
SN  - 0018-4888
VL  - 360
IS  - 2
SP  - 1535
EP  - 1548
ER  - 
TY  - JOUR
A1  - Wolf, Günter
A1  - Berndt, Heinz
A1  - Brandenburg, Dietrich
T1  - Synthese der [LysA13] Rinderinsulin-A-Kette in der Form [Lys(Tfa)A13]A(SO3H)4 und NαA1-Msc-[LysA13]A(SO3H)4 unter Verwendung des S-tert-Butylmercapto-Restes als Thiolschutzgruppe
JF  - Hoppe-Seyler's Zeitschrift für physiologische Chemie
Y1  - 1979
U6  - http://dx.doi.org/10.1515/bchm2.1979.360.2.1569
SN  - 1437-4315
SN  - 0018-4888
VL  - 360
IS  - 2
SP  - 1569
EP  - 1578
ER  - 
TY  - JOUR
A1  - Turck, Christoph W.
A1  - Berndt, Heinz
T1  - Synthese definierter Peptid-Derivate durch Aminolyse von 3-(Nα-Acyl-peptidyloxy)-2-hydroxy-N-alkylbenzamiden bei erhöhten Temperaturen, I : Synthese des Modellpeptid-Derivates Z-Ala-Phe-Gly-N(Et)2
JF  - Hoppe-Seyler´s Zeitschrift für physiologische Chemie
Y1  - 1981
U6  - http://dx.doi.org/10.1515/bchm2.1981.362.1.821
SN  - 1437-4315
SN  - 0018-4888
VL  - 362
IS  - 1
SP  - 821
EP  - 828
ER  - 
TY  - JOUR
A1  - Esch, Thomas
A1  - Salber, Wolfgang
A1  - Wolters, Peter
A1  - Geiger, José
A1  - Dilthey, Jochen
T1  - Synergies of variable valve actuation and direct injection
JF  - Direct injection SI engine technology 2002 : [SAE 2002 world congress, Detroit, Michigan, USA, March 4 - 7, 2002].
Y1  - 2002
SN  - 0-7680-0961-8
N1  - Konferenz-Einzelbericht
SP  - 45
EP  - 53
PB  - Society of Automotive Engineers
CY  - Warrendale, Pa
ER  - 
TY  - JOUR
A1  - Lehnertz, Klaus
A1  - Bialonski, Stephan
A1  - Horstmann, Marie-Therese
A1  - Krug, Dieter
A1  - Rothkegel, Alexander
A1  - Staniek, Matthäus
A1  - Wagner, Tobias
T1  - Synchronization phenomena in human epileptic brain networks
JF  - Journal of neuroscience methods
Y1  - 2009
U6  - http://dx.doi.org/10.1016/j.jneumeth.2009.05.015
SN  - 0165-0270
VL  - 183
IS  - 1
SP  - 42
EP  - 48
ER  - 
TY  - JOUR
A1  - Kodomskoi, Leonid
A1  - Kotliar, Konstantin
A1  - Schröder, Andreas
A1  - Weiss, Michael
A1  - Hille, Konrad
T1  - Suture-Probe Canaloplasty as an Alternative to Canaloplasty using the iTrack™ Microcatheter
JF  - Journal of Glaucoma
Y1  - 2019
U6  - http://dx.doi.org/10.1097/IJG.0000000000001321
SN  - 1057-0829
IS  - Epub ahead of print
PB  - Lippincott Williams & Wilkins
CY  - Philadelphia
ER  - 
TY  - JOUR
A1  - Hackl, M.
A1  - Andermahr, J.
A1  - Staat, Manfred
A1  - Bremer, I.
A1  - Borggrefe, J.
A1  - Prescher, A.
A1  - Müller, L. P.
A1  - Wegmann, K.
T1  - Suture button reconstruction of the central band of the interosseous membrane in Essex-Lopresti lesions: a comparative biomechanical investigation
JF  - The Journal of Hand Surgery (European Volume)
Y1  - 2017
U6  - http://dx.doi.org/10.1177/1753193416665943
SN  - 2043-6289 (Online)
SN  - 1753-1934 (Print)
VL  - 42
IS  - 4
SP  - 370
EP  - 376
PB  - Sage
CY  - London
ER  - 
TY  - JOUR
A1  - Bernecker, Andreas
A1  - Klier, Julia
A1  - Stern, Sebastian
A1  - Thiel, Lea
T1  - Sustaining high performance beyond public-sector pilot projects.
Y1  - 2018
IS  - September 2018
ER  - 
TY  - JOUR
A1  - Leise, Philipp
A1  - Eßer, Arved
A1  - Eichenlaub, Tobias
A1  - Schleiffer, Jean-Eric
A1  - Altherr, Lena
A1  - Rinderknecht, Stephan
A1  - Pelz, Peter F.
T1  - Sustainable system design of electric powertrains - comparison of optimization methods
JF  - Engineering Optimization
N2  - The transition within transportation towards battery electric vehicles can lead to a more sustainable future. To account for the development goal ‘climate action’ stated by the United Nations, it is mandatory, within the conceptual design phase, to derive energy-efficient system designs. One barrier is the uncertainty of the driving behaviour within the usage phase. This uncertainty is often addressed by using a stochastic synthesis process to derive representative driving cycles and by using cycle-based optimization. To deal with this uncertainty, a new approach based on a stochastic optimization program is presented. This leads to an optimization model that is solved with an exact solver. It is compared to a system design approach based on driving cycles and a genetic algorithm solver. Both approaches are applied to find efficient electric powertrains with fixed-speed and multi-speed transmissions. Hence, the similarities, differences and respective advantages of each optimization procedure are discussed.
KW  - Powertrain
KW  - stochastic optimization
KW  - global optimization
KW  - genetic algorithm
Y1  - 2021
U6  - http://dx.doi.org/10.1080/0305215X.2021.1928660
SN  - 0305-215X
PB  - Taylor & Francis
CY  - London
ER  - 
TY  - JOUR
A1  - Hafidi, Youssef
A1  - El Hatka, Hicham
A1  - Schmitz, Dominik
A1  - Krauss, Manuel
A1  - Pettrak, Jürgen
A1  - Biel, Markus
A1  - Ittobane, Najim
T1  - Sustainable soil additives for water and micronutrient supply: swelling and chelating properties of polyaspartic acid hydrogels utilizing newly developed crosslinkers
JF  - Gels
N2  - Drought and water shortage are serious problems in many arid and semi-arid regions. This problem is getting worse and even continues in temperate climatic regions due to climate change. To address this problem, the use of biodegradable hydrogels is increasingly important for the application as water-retaining additives in soil. Furthermore, efficient (micro-)nutrient supply can be provided by the use of tailored hydrogels. Biodegradable polyaspartic acid (PASP) hydrogels with different available (1,6-hexamethylene diamine (HMD) and L-lysine (LYS)) and newly developed crosslinkers based on diesters of glycine (GLY) and (di-)ethylene glycol (DEG and EG, respectively) were synthesized and characterized using Fourier transform infrared (FTIR) spectroscopy and scanning electron microscopy (SEM) and regarding their swelling properties (kinetic, absorbency under load (AUL)) as well as biodegradability of PASP hydrogel. Copper (II) and zinc (II), respectively, were loaded as micronutrients in two different approaches: in situ with crosslinking and subsequent loading of prepared hydrogels. The results showed successful syntheses of di-glycine-ester-based crosslinkers. Hydrogels with good water-absorbing properties were formed. Moreover, the developed crosslinking agents in combination with the specific reaction conditions resulted in higher water absorbency with increased crosslinker content used in synthesis (10% vs. 20%). The prepared hydrogels are candidates for water-storing soil additives due to the biodegradability of PASP, which is shown in an exemple. The incorporation of Cu(II) and Zn(II) ions can provide these micronutrients for plant growth.
KW  - micronutrients
KW  - swelling properties
KW  - biodegradable polymers
KW  - hydrogels
KW  - superabsorbent polymers
KW  - glycine
KW  - polyaspartic acid
Y1  - 2024
U6  - http://dx.doi.org/10.3390/gels10030170
SN  - 2310-2861
VL  - 10
IS  - 3
SP  - Artikel 170
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Digel, Ilya
A1  - Wehlitz, V.
A1  - Kayser, Peter
A1  - Figiel-Lange, A.
A1  - Bassam, R.
A1  - Rundstedt, F. von
T1  - Suspension depletion approach for exemption of infected Solanum jasminoides cells from pospiviroids
JF  - Plant Pathology
N2  - Despite numerous studies, viroid elimination from infected plants remains a very challenging task. This study introduces for the first time a novel ‘suspension depletion’ approach for exemption of Solanum jasminoides plants from viroids. The proposed method implies initial establishment of suspension cultures of the infected plant cells. The suspended cells were then physically treated (mild thermotherapy, 33 °C), which presumably delayed the replication of the viroid. The viroid concentration in the treated biomass was monitored weekly using pospiviroid-specific PCR. After 10–12 weeks of continuous treatment, a sufficient decrease in viroid concentration was observed such that the infection became undetectable by PCR. The treated single cells then gave rise to microcolonies on a solid culture medium and the obtained viroid-negative clones were further promoted to regenerate into viroid-free plants. Three years of accumulated experimental data suggests feasibility, broad applicability, and good efficacy of the proposed approach.
Y1  - 2018
U6  - http://dx.doi.org/10.1111/ppa.12750
SN  - 1365-3059
VL  - 67
IS  - 2
SP  - 358
EP  - 365
PB  - Wiley
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Herrmann, Ulf
A1  - Kearney, David W.
T1  - Survey of Thermal Energy Storage for Parabolic Trough Power Plants
JF  - Journal of Solar Energy Engineering
Y1  - 2002
U6  - http://dx.doi.org/10.1115/1.1467601
SN  - 1528-8986 (Online)
SN  - 0199-6231 (Print)
VL  - 124
IS  - 2
SP  - 145
EP  - 152
ER  - 
TY  - JOUR
A1  - Kern, Alexander
A1  - Drumm, F.
T1  - Survey of the lightning threat for aircraft based on natural lightning data and fixed in the German Standard DIN VG 95371 / Part 10
JF  - Proceedings of the 1994 International Aerospace and Ground Conference on Lightning and Static Electricity : May 14 - 27, 1994, Bundesakademie für Wehrverwaltung und Wehrtechnik Mannheim ; final report / [conference chairman Jan Luiken TerHaseborg]
Y1  - 1994
N1  - International Aerospace and Ground Conference on Lightning and Static Electricity <16, 1994, Mannheim>
PB  - Bundesakad. für Wehrverwaltung und Wehrtechnik
CY  - Mannheim
ER  - 
TY  - JOUR
A1  - Bhattarai, Aroj
A1  - Jabbari, Medisa
A1  - Anding, Ralf
A1  - Staat, Manfred
T1  - Surgical treatment of vaginal vault prolapse using different prosthetic mesh implants: a finite element analysis
JF  - tm - Technisches Messen
N2  - Particularly multiparous elderly women may suffer from vaginal vault prolapse after hysterectomy due to weak support from lax apical ligaments. A decreased amount of estrogen and progesterone in older age is assumed to remodel the collagen thereby reducing tissue stiffness. Sacrocolpopexy is either performed as open or laparoscopic surgery using prosthetic mesh implants to substitute lax ligaments. Y-shaped mesh models (DynaMesh, Gynemesh, and Ultrapro) are implanted in a 3D female pelvic floor finite element model in the extraperitoneal space from the vaginal cuff to the first sacral (S1) bone below promontory. Numerical simulations are conducted during Valsalva maneuver with weakened tissues modeled by reduced tissue stiffness. Tissues are modeled as incompressible, isotropic hyperelastic materials whereas the meshes are modeled either as orthotropic linear elastic or as isotropic hyperlastic materials. The positions of the vaginal cuff and the bladder base are calculated from the pubococcygeal line for female pelvic floor at rest, for prolapse and after repair using the three meshes. Due to mesh mechanics and mesh pore deformation along the loaded direction, the DynaMesh with regular rectangular mesh pores is found to provide better mechanical support to the organs than the Gynemesh and the Ultrapro with irregular hexagonal mesh pores.

Insbesondere ältere, mehrgebährende Frauen leiden häufiger an einem Scheidenvorfall nach einer Hysterektomie aufgrund der schwachen Unterstützung durch laxe apikale Bänder. Es wird angenommen, dass eine verringerte Menge an Östrogen und Progesteron im höheren Alter das Kollagen umformt, wodurch die Gewebesteifigkeit reduziert wird. Die Sakrokolpopexie ist eine offene oder laparoskopische Operation, die mit prothetischen Netzimplantaten durchgeführt wird, um laxe Bänder zu ersetzen. Y-förmige Netzmodelle (DynaMesh, Gynemesh und Ultrapro) werden in einem 3D-Modell des weiblichen Beckenbodens im extraperitonealen Raum vom Vaginalstumpf bis zum Promontorium implantiert. Numerische Simulationen werden während des Valsalva-Manövers mit geschwächtem Gewebe durchgeführt, das durch eine reduzierte Gewebesteifigkeit modelliert wird. Die Gewebe werden als inkompressible, isotrop hyperelastische Materialien modelliert, während die Netze entweder als orthotrope linear elastische oder als isotrope hyperlastische Materialien modelliert werden. Die Positionen des Vaginalstumpfs, der Blase und der Harnröhrenachse werden anhand der Pubococcygeallinie aus der Ruhelage, für den Prolaps und nach der Reparatur unter Verwendung der drei Netze berechnet. Aufgrund der Netzmechanik und der Netzporenverformung bietet das DynaMesh mit regelmäßigen rechteckigen Netzporen eine bessere mechanische Unterstützung und eine Neupositionierung des Scheidengewölbes, der Blase und der Urethraachse als Gynemesh und Ultrapro mit unregelmäßigen hexagonalen Netzporen.
Y1  - 2018
U6  - http://dx.doi.org/10.1515/teme-2017-0115
SN  - 2196-7113
VL  - 85
IS  - 5
SP  - 331
EP  - 342
PB  - De Gruyter
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Balakirski, Galina
A1  - Kotliar, Konstantin
A1  - Pauly, Karolin J.
A1  - Krings, Laura K.
A1  - Rübben, Albert
A1  - Baron, Jens M.
A1  - Schmitt, Laurenz
T1  - Surgical Site Infections After Dermatologic Surgery in Immunocompromised Patients: A Single-Center Experience
JF  - Dermatologic Surgery
N2  - BACKGROUND 
Immunosuppression is often considered as an indication for antibiotic prophylaxis to prevent surgical site infections (SSI) while performing skin surgery. However, the data on the risk of developing SSI after dermatologic surgery in immunosuppressed patients are limited.

PATIENTS AND METHODS 
All patients of the Department of Dermatology and Allergology at the University Hospital of RWTH Aachen in Aachen, Germany, who underwent hospitalization for a dermatologic surgery between June 2016 and January 2017 (6 months), were followed up after surgery until completion of the wound healing process. The follow-up addressed the occurrence of SSI and the need for systemic antibiotics after the operative procedure. Immunocompromised patients were compared with immunocompetent patients. The investigation was conducted as a retrospective analysis of patient records.

RESULTS 
The authors performed 284 dermatologic surgeries in 177 patients. Nineteen percent (54/284) of the skin surgery was performed on immunocompromised patients. The most common indications for surgical treatment were nonmelanoma skin cancer and malignant melanomas. Surgical site infections occurred in 6.7% (19/284) of the cases. In 95% (18/19), systemic antibiotic treatment was needed. Twenty-one percent of all SSI (4/19) were seen in immunosuppressed patients.

CONCLUSION 
According to the authors' data, immunosuppression does not represent a significant risk factor for SSI after dermatologic surgery. However, larger prospective studies are needed to make specific recommendations on the use of antibiotic prophylaxis while performing skin surgery in these patients.

The available data on complications after dermatologic surgery have improved over the past years. Particularly, additional risk factors have been identified for surgical site infections (SSI). Purulent surgical sites, older age, involvement of head, neck, and acral regions, and also the involvement of less experienced surgeons have been reported to increase the risk of the SSI after dermatologic surgeries.1 In general, the incidence of SSI after skin surgery is considered to be low.1,2 However, antibiotics in dermatologic surgeries, especially in the perioperative setting, seem to be overused,3,4 particularly regarding developing antibiotic resistances and side effects.

Immunosuppression has been recommended to be taken into consideration as an additional indication for antibiotic prophylaxis to prevent SSI after skin surgery in special cases.5,6 However, these recommendations do not specify the exact dermatologic surgeries, and were not specifically developed for dermatologic surgery patients and treatments, but adopted from other surgical fields.6 According to the survey conducted on American College of Mohs Surgery members in 2012, 13% to 29% of the surgeons administered antibiotic prophylaxis to immunocompromised patients to prevent SSI while performing dermatologic surgery on noninfected skin,3 although this was not recommended by Journal of the American Academy of Dermatology Advisory Statement. Indeed, the data on the risk of developing SSI after dermatologic surgery in immunosuppressed patients are limited. However, it is possible that due to the insufficient evidence on the risk of SSI occurrence in this patient group, dermatologic surgeons tend to overuse perioperative antibiotic prophylaxis.

To make specific recommendations on the use of antibiotic prophylaxis in immunosuppressed patients in the field of skin surgery, more information about the incidence of SSI after dermatologic surgery in these patients is needed. The aim of this study was to fill this data gap by investigating whether there is an increased risk of SSI after skin surgery in immunocompromised patients compared with immunocompetent patients.
Y1  - 2018
U6  - http://dx.doi.org/10.1097/DSS.0000000000001615
IS  - 44 (12)
SP  - 1525
EP  - 1536
PB  - Wolters Kluwer
ER  - 
TY  - JOUR
A1  - Hamou, Hussam Aldin
A1  - Kotliar, Konstantin
A1  - Tan, Sonny Kian
A1  - Weiß, Christel
A1  - Blume, Christian
A1  - Clusmann, Hans
A1  - Schubert, Gerrit Alexander
A1  - Albanna, Walid
T1  - Surgical nuances and placement of subgaleal drains for supratentorial procedures—a prospective analysis of efficacy and outcome in 150 craniotomies
JF  - Acta Neurochirurgica
N2  - Background
For supratentorial craniotomy, surgical access, and closure technique, including placement of subgaleal drains, may vary considerably. The influence of surgical nuances on postoperative complications such as cerebrospinal fluid leakage or impaired wound healing overall remains largely unclear. With this study, we are reporting our experiences and the impact of our clinical routines on outcome in a prospectively collected data set.

Method
We prospectively observed 150 consecutive patients undergoing supratentorial craniotomy and recorded technical variables (type/length of incision, size of craniotomy, technique of dural and skin closure, type of dressing, and placement of subgaleal drains). Outcome variables (subgaleal hematoma/CSF collection, periorbital edema, impairment of wound healing, infection, and need for operative revision) were recorded at time of discharge and at late follow-up.

Results
Early subgaleal fluid collection was observed in 36.7% (2.8% at the late follow-up), and impaired wound healing was recorded in 3.3% of all cases, with an overall need for operative revision of 6.7%. Neither usage of dural sealants, lack of watertight dural closure, and presence of subgaleal drains, nor type of skin closure or dressing influenced outcome. Curved incisions, larger craniotomy, and tumor size, however, were associated with an increase in early CSF or hematoma collection (p < 0.0001, p = 0.001, p < 0.01 resp.), and larger craniotomy size was associated with longer persistence of subgaleal fluid collections (p < 0.05).

Conclusions
Based on our setting, individual surgical nuances such as the type of dural closure and the use of subgaleal drains resulted in a comparable complication rate and outcome. Subgaleal fluid collections were frequently observed after supratentorial procedures, irrespective of the closing technique employed, and resolve spontaneously in the majority of cases without significant sequelae. Our results are limited due to the observational nature in our single-center study and need to be validated by supportive prospective randomized design.
Y1  - 2020
U6  - http://dx.doi.org/10.1007/s00701-019-04196-6
SN  - 0942-0940
VL  - 2020
IS  - 162
SP  - 729
EP  - 736
PB  - Springer Nature
CY  - Cham
ER  -