TY  - CHAP
A1  - Pijanowska, Dorota G.
A1  - Remiszewska, Elzbieta
A1  - Pederzolli, Cecilia
A1  - Lunelli, Lorenzo
A1  - Vendano, Michele
A1  - Canteri, Roberto
A1  - Dudzinski, Konrad
A1  - Kruk, Jerzy
A1  - Torbicz, Wladyslaw
T1  - Surface modification for microreactor fabrication
N2  - In this paper, methods of surface modification of different supports, i.e. glass and polymeric beads for enzyme immobilisation are described. The developed method of enzyme immobilisation is based on Schiff’s base formation between the amino groups on the enzyme surface and the aldehyde groups on the chemically modified surface of the supports. The surface of silicon modified by APTS and GOPS with immobilised enzyme was characterised by atomic force microscopy (AFM), time-of-flight secondary ion mass spectroscopy (ToF-SIMS) and infrared spectroscopy (FTIR). The supports with immobilised enzyme (urease) were also tested in combination with microreactors fabricated in silicon and Perspex, operating in a flow-through system. For microreactors filled with urease immobilised on glass beads (Sigma) and on polymeric beads (PAN), a very high and stable signal (pH change) was obtained. The developed method of urease immobilisation can be stated to be very effective.
KW  - Biosensor
KW  - Microreactors
KW  - surface modification
KW  - enzyme immobilisation
KW  - lab-on-a-chip
Y1  - 2006
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:a96-opus-1480
ER  - 
TY  - CHAP
A1  - Koplin, Tobias J.
A1  - Siemons, Maike
A1  - Océn-Valéntin, César
A1  - Sanders, Daniel
A1  - Simon, Ulrich
T1  - Workflow for high throughput screening of gas sensing materials
N2  - The workflow of a high throughput screening setup for the rapid identification of new and improved sensor materials is presented. The polyol method was applied to prepare nanoparticular metal oxides as base materials, which were functionalised by surface doping. Using multi-electrode substrates and high throughput impedance spectroscopy (HT-IS) a wide range of materials could be screened in a short time. Applying HT-IS in search of new selective gas sensing materials a NO2-tolerant NO sensing material with reduced sensitivities towards other test gases was identified based on iridium doped zinc oxide. Analogous behaviour was observed for iridium doped indium oxide.
KW  - Biosensor
KW  - High throughput experimentation
KW  - gas sensor
KW  - metal oxide
KW  - doping
KW  - impedance spectroscopy
KW  - nitrogen oxides
Y1  - 2006
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:a96-opus-1407
ER  -