TY  - JOUR
A1  - Muschallik, Lukas
A1  - Molinnus, Denise
A1  - Bongaerts, Johannes
A1  - Pohl, Martina
A1  - Wagner, Torsten
A1  - Schöning, Michael Josef
A1  - Siegert, Petra
A1  - Selmer, Thorsten
T1  - (R,R)-Butane-2,3-diol Dehydrogenase from Bacillus clausii DSM 8716T: Cloning and Expression of the bdhA-Gene, and Initial Characterization of Enzyme
JF  - Journal of Biotechnology
N2  - The gene encoding a putative (R,R)-butane-2,3-diol dehydrogenase (bdhA) from Bacillus clausii DSM 8716T was isolated, sequenced and expressed in Escherichia coli. The amino acid sequence of the encoded protein is only distantly related to previously studied enzymes (identity 33–43%) and exhibited some uncharted peculiarities. An N-terminally StrepII-tagged enzyme variant was purified and initially characterized. The isolated enzyme catalyzed the (R)-specific oxidation of (R,R)- and meso-butane-2,3-diol to (R)- and (S)-acetoin with specific activities of 12 U/mg and 23 U/mg, respectively. Likewise, racemic acetoin was reduced with a specific activity of up to 115 U/mg yielding a mixture of (R,R)- and meso-butane-2,3-diol, while the enzyme reduced butane-2,3-dione (Vmax 74 U/mg) solely to (R,R)-butane-2,3-diol via (R)-acetoin. For these reactions only activity with the co-substrates NADH/NAD+ was observed. The enzyme accepted a selection of vicinal diketones, α-hydroxy ketones and vicinal diols as alternative substrates. Although the physiological function of the enzyme in B. clausii remains elusive, the data presented herein clearly demonstrates that the encoded enzyme is a genuine (R,R)-butane-2,3-diol dehydrogenase with potential for applications in biocatalysis and sensor development.
Y1  - 2017
U6  - http://dx.doi.org/10.1016/j.jbiotec.2017.07.020
SN  - 0168-1656
VL  - 258
SP  - 41
EP  - 50
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Wilke, Thomas
T1  - [Rezension zu:] Deutsch, Kristina: Jean Marot. Un graveur d'architecture à l'époque de Louis XIV. (= Ars et Scientia; 12), Berlin; Boston 2015.
JF  - ArtHist.net
Y1  - 2017
ER  - 
TY  - JOUR
A1  - Miyamoto, Ko-ichiro
A1  - Hayashi, Kosuke
A1  - Sakamoto, Azuma
A1  - Werner, Frederik
A1  - Wagner, Torsten
A1  - Schöning, Michael Josef
A1  - Yoshinobu, Tatsuo
T1  - A high-Q resonance-mode measurement of EIS capacitive sensor by elimination of series resistance
JF  - Sensor and Actuators B: Chemical
N2  - An EIS capacitive sensor is a semiconductor-based potentiometric sensor, which is sensitive to the ion concentration or pH value of the solution in contact with the sensing surface. To detect a small change in the ion concentration or pH, a small capacitance change must be detected. Recently, a resonance-mode measurement was proposed, in which an inductor was connected to the EIS capacitive sensor and the resonant frequency was correlated with the pH value. In this study, the Q factor of the resonant circuit was enhanced by canceling the internal resistance of the reference electrode and the internal resistance of the inductor coil with the help of a bypass capacitor and a negative impedance converter, respectively. 1% variation of the signal in the developed system corresponded to a pH change of 3.93 mpH, which was about 1/12 of the conventional method, suggesting a better performance in detection of a small pH change.
KW  - Negative impedance convertor
KW  - Resonance-mode measurement
KW  - Chemical sensor
KW  - EIS capacitive sensor
Y1  - 2017
U6  - http://dx.doi.org/10.1016/j.snb.2017.03.002
SN  - 0925-4005
VL  - 248
SP  - 1006
EP  - 1010
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Mayer, Jan
A1  - Hentschke, Reinhard
A1  - Hager, Jonathan
A1  - Hojdis, Nils
A1  - Karimi-Varnaneh, Hossein Ali
T1  - A Nano-Mechanical Instability as Primary Contribution to Rolling Resistance
JF  - Scientific Reports
Y1  - 2017
SN  - 2045-2322
VL  - 7
IS  - Article number 11275
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Garibaldi, F.
A1  - Beging, Stefan
A1  - Canese, R.
A1  - Carpinelli, G.
A1  - Clinthorne, N.
A1  - Colilli, S.
A1  - Cosentino, L.
A1  - Finocchiaro, P.
A1  - Giuliani, F.
A1  - Gricia, M.
A1  - Lucentini, M.
A1  - Majewski, S.
A1  - Monno, E.
A1  - Musico, P.
A1  - Santavenere, F.
A1  - Tödter, J.
A1  - Wegener, Hans-Peter
A1  - Ziemons, Karl
T1  - A novel TOF-PET MRI detector for diagnosis and follow up of the prostate cancer
JF  - European Physical Journal Plus
Y1  - 2017
U6  - http://dx.doi.org/10.1140/epjp/i2017-11662-x
SN  - 2190-5444
VL  - 132
IS  - 9
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Weber, Tobias
A1  - Ruff-Stahl, Hans-Joachim K.
T1  - Advances in Composite Manufacturing of Helicopter Parts
JF  - International Journal of Aviation, Aeronautics, and Aerospace
Y1  - 2017
U6  - http://dx.doi.org/10.15394/ijaaa.2017.1153
SN  - 2374-6793
VL  - 4
IS  - 1
ER  - 
TY  - JOUR
A1  - Alexopoulos, Spiros
A1  - Hoffschmidt, Bernhard
T1  - Advances in solar tower technology
JF  - Wiley interdisciplinary reviews : Energy and Environment : WIREs
Y1  - 2017
U6  - http://dx.doi.org/10.1002/wene.217
SN  - 2041-840X
VL  - 6
IS  - 1
SP  - 1
EP  - 19
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Müller, Wolfram
A1  - Jung, Alexander
A1  - Ahammer, Helmut
T1  - Advantages and problems of nonlinear methods applied to analyze physiological time signals: human balance control as an example
JF  - Scientific Reports
Y1  - 2017
SN  - 2045-2322
U6  - http://dx.doi.org/10.1038/s41598-017-02665-5
VL  - 7
IS  - Article number 2464
SP  - 1
EP  - 11
PB  - Springer Nature
CY  - Cham
ER  - 
TY  - JOUR
A1  - Engelmann, Ulrich M.
A1  - Buhl, Eva Miriam
A1  - Baumann, Martin
A1  - Schmitz-Rode, Thomas
A1  - Slabu, Ioana
T1  - Agglomeration of magnetic nanoparticles and its effects on magnetic hyperthermia
JF  - Current Directions in Biomedical Engineering
Y1  - 2017
U6  - http://dx.doi.org/10.1515/cdbme-2017-0096
SN  - 2364-5504
VL  - 3
IS  - 2
SP  - 457
EP  - 460
PB  - De Gruyter
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Hauser, Christine
A1  - Ortner, Marion
A1  - Muggenthaler, Claudia
A1  - Diehl-Schmid, Janine
A1  - Angermann, Susanne
A1  - Hapfelmeier, Alexander
A1  - Schmaderer, Christoph
A1  - Grimmer, Timo
T1  - Altered neurovascular coupling as measured by optical imaging: a biomarker for Alzheimer’s disease
JF  - Scientific Reports
Y1  - 2017
U6  - http://dx.doi.org/10.1038/s41598-017-13349-5
SN  - 2045-2322
N1  - Article 12906
VL  - 7
IS  - 1
SP  - 1
EP  - 11
PB  - Springer Nature
CY  - Cham
ER  - 
TY  - JOUR
A1  - Lopes, Pedro
A1  - Leandro, Jorge
A1  - Carvalho, Rita F.
A1  - Bung, Daniel B.
T1  - Alternating skimming flow over a stepped spillway
JF  - Environmental Fluid Mechanics
Y1  - 2017
U6  - http://dx.doi.org/10.1007/s10652-016-9484-x
SN  - 1573-1510
VL  - 17
IS  - 2
SP  - 303
EP  - 322
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Rietsch, Stefan H. G.
A1  - Pfaffenrot, Viktor
A1  - Bitz, Andreas
A1  - Orzada, Stephan
A1  - Brunheim, Sascha
A1  - Lazik-Palm, Andrea
A1  - Theysohn, Jens M.
A1  - Ladd, Mark E.
A1  - Quick, Harald H.
A1  - Kraff, Oliver
T1  - An 8-channel transceiver 7-channel receive RF coil setup for high SNR ultrahigh-field MRI of the shoulder at 7T
JF  - Medical Physics
Y1  - 2017
U6  - http://dx.doi.org/10.1002/mp.12612
SN  - 0094-2405
IS  - Article in press
PB  - Wiley
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Honarvarfard, Elham
A1  - Gamella, Maria
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
A1  - Katz, Evgeny
T1  - An enzyme-based reversible Controlled NOT (CNOT) logic gate operating on a semiconductor transducer
JF  - Applied Materials Today
N2  - An enzyme-based biocatalytic system mimicking operation of a logically reversible Controlled NOT (CNOT) gate has been interfaced with semiconductor electronic transducers. Electrolyte–insulator–semiconductor (EIS) structures have been used to transduce chemical changes produced by the enzyme system to an electronically readable capacitive output signal using field-effect features of the EIS device. Two enzymes, urease and esterase, were immobilized on the insulating interface of EIS structure producing local pH changes performing XOR logic operation controlled by various combinations of the input signals represented by urea and ethyl butyrate. Another EIS transducer was functionalized with esterase only, thus performing Identity (ID) logic operation for the ethyl butyrate input. Both semiconductor devices assembled in parallel operated as a logically reversible CNOT gate. The present system, despite its simplicity, demonstrated for the first time logically reversible function of the enzyme system transduced electronically with the semiconductor devices. The biomolecular realization of a CNOT gate interfaced with semiconductors is promising for integration into complex biomolecular networks and future biosensor/biomedical applications.
KW  - Electrolyte–insulator–semiconductor
KW  - Capacitive field-effect
KW  - CNOT
KW  - XOR
KW  - Enzyme logic gate
Y1  - 2017
U6  - http://dx.doi.org/10.1016/j.apmt.2017.08.003
SN  - 2352-9407
VL  - 9
SP  - 266
EP  - 270
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Tran, Linda
A1  - Mottaghy, K.
A1  - Arlt-Körfer, Sabine
A1  - Waluga, Christian
A1  - Behbahani, Mehdi
T1  - An experimental study of shear-dependent human platelet adhesion and underlying protein-binding mechanisms in a cylindrical Couette system
JF  - Biomedizinische Technik
Y1  - 2017
U6  - http://dx.doi.org/10.1515/bmt-2015-0034
SN  - 0013-5585
VL  - 62
IS  - 4
SP  - 383
EP  - 392
PB  - De Gruyter
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Orzada, Stephan
A1  - Bitz, Andreas
A1  - Johst, Sören
A1  - Gratz, Marcel
A1  - Völker, Maximilian N.
A1  - Kraff, Oliver
A1  - Abuelhaija, Ashraf
A1  - Fiedler, Thomas M.
A1  - Solbach, Klaus
A1  - Quick, Harald H.
A1  - Ladd, Mark E.
T1  - Analysis of an integrated 8-Channel Tx/Rx body array for use as a body coil in 7-Tesla MRI
JF  - Frontiers in Physics
Y1  - 2017
U6  - http://dx.doi.org/10.3389/fphy.2017.00017
SN  - 2296-424X
N1  - Article number 17
VL  - 5
IS  - Jun
ER  - 
TY  - JOUR
A1  - Butenweg, Christoph
A1  - Rosin, Julia
A1  - Holler, Stefan
T1  - Analysis of cylindrical granular material silos under seismic excitation
JF  - Buildings
N2  - Silos generally work as storage structures between supply and demand for various goods, and their structural safety has long been of interest to the civil engineering profession. This is especially true for dynamically loaded silos, e.g., in case of seismic excitation. Particularly thin-walled cylindrical silos are highly vulnerable to seismic induced pressures, which can cause critical buckling phenomena of the silo shell. The analysis of silos can be carried out in two different ways. In the first, the seismic loading is modeled through statically equivalent loads acting on the shell. Alternatively, a time history analysis might be carried out, in which nonlinear phenomena due to the filling as well as the interaction between the shell and the granular material are taken into account. The paper presents a comparison of these approaches. The model used for the nonlinear time history analysis considers the granular material by means of the intergranular strain approach for hypoplasticity theory. The interaction effects between the granular material and the shell is represented by contact elements. Additionally, soil–structure interaction effects are taken into account.
KW  - granular silo
KW  - earthquake engineering
KW  - hypoplasticity
KW  - nonlinear transient analyses
Y1  - 2017
U6  - http://dx.doi.org/10.3390/buildings7030061
SN  - 2075-5309
VL  - 7
IS  - 3
SP  - 1
EP  - 12
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Pfaff, Raphael
T1  - Apps für den Güterwagen? Wie der Güterwagen 4.0 die effiziente Integration der Güterbahn in ERTMS ermöglicht
JF  - Ingenieurspiegel
Y1  - 2017
IS  - 2
SP  - 1
EP  - 2
ER  - 
TY  - JOUR
A1  - Olbertz, Klaus
T1  - Arbeitsrechtliche Aspekte beim Rechtsformwechsel
JF  - Gesellschafts- und Wirtschaftsrecht : GWR
Y1  - 2018
SN  - 1868-1816
SP  - 314
EP  - 317
PB  - Beck
CY  - München
ER  - 
TY  - JOUR
A1  - Valero, Daniel
A1  - Bung, Daniel B.
T1  - Artificial Neural Networks and pattern recognition for air-water flow velocity estimation using a single-tip optical fibre probe
JF  - Journal of Hydro-environment Research
Y1  - 2017
U6  - http://dx.doi.org/10.1016/j.jher.2017.08.004
SN  - 1570-6443
VL  - 19
IS  - 3
SP  - 150
EP  - 159
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Olbertz, Klaus
T1  - Aufhebungsverträge und Sperrzeit beim Bezug von Arbeitslosengeld - Neue Gestaltungsmöglichkeiten aufgrund geänderter Geschäftsanweisung der Bundesagentur für Arbeit
JF  - NWB - Steuer- und Wirtschaftsrecht
Y1  - 2018
SN  - 1860-9449
IS  - 21
SP  - 1588
EP  - 1593
ER  -