TY  - JOUR
A1  - Bialonski, Stephan
A1  - Schindler, K.
A1  - Elger, C. E.
A1  - Lehnertz, Klaus
T1  - Lateralized characteristics of the evolution of EEG correlation during focal onset seizures: a mechanism to prevent secondary generalization?
JF  - Epilepsia
N2  - Rationale: Previous studies [Topolnik et al., Cereb Cortex 2003; 13: 883; Schindler et al., Brain 2007; 130: 65] indicate that the termination of focal onset seizures may be causally related to an increase of global neuronal correlation during the second half of the seizures. This increase was observed to occur earlier in complex partial seizures than in secondarily generalized seizures. We here address the question whether such an increase of neuronal correlation prior to seizure end is indeed a global phenomenon, involving both hemispheres or whether there are side-specific differences. Methods: We analyzed 20 focal onset seizures (10 complex partial, 10 secondarily generalized seizures) recorded in 13 patients who underwent presurgical evaluation of focal epilepsies of different origin. EEG was recorded intracranially from bilaterally implanted subdural strip and intrahippocampal depth electrodes. Utilizing a moving window approach, we investigated the evolution of the maximum cross correlation for all channel combinations during seizures. For each moving window the mean value of the maximum cross correlation (MCC) between all electrode contacts was computed separately for each hemisphere. After normalization of seizure durations, MCC values of the ipsi- and contralateral hemisphere for all seizures were determined. Results: We observed that the MCC of the contralateral hemisphere in complex partial seizures increased during the first half of the seizure, whereas, for the same time interval, the MCC of the ipsilateral hemisphere even declined below the level of the pre-seizure period. In contrast, no significant differences between both hemispheres could be observed for secondarily generalized seizures where both hemispheres showed a simultaneous increase of MCC during the second half of the seizures. The level of MCC for the contralateral hemisphere was higher for complex partial seizures than for secondarily generalized seizures during the first half of the seizure. Conclusions: Our findings indicate that there are indeed lateralized differences in the evolution of global neuronal correlation during complex partial and secondarily generalized seizures. The observed contralateral increase of neuronal correlation during complex partial seizures might indicate an emerging self-organizing mechanism for preventing the spread of seizure activity.
Y1  - 2008
SN  - 0013-9580
VL  - 49
SP  - 11
EP  - 11
ER  - 
TY  - JOUR
A1  - Bialonski, Stephan
A1  - Allefeld, C.
A1  - Wellmer, J.
A1  - Elger, C.
A1  - Lehnertz, K.
T1  - An approach to identify synchronization clusters within the epileptic network
JF  - Klinische Neurophysiologie
Y1  - 2008
U6  - http://dx.doi.org/10.1055/s-2008-1072881
VL  - 39
IS  - 1
SP  - A79
ER  - 
TY  - JOUR
A1  - Schindler, Kaspar A.
A1  - Bialonski, Stephan
A1  - Horstmann, Marie-Therese
A1  - Elger, Christian E.
A1  - Lehnertz, Klaus
T1  - Evolving functional network properties and synchronizability during human epileptic seizures
JF  - Chaos: An Interdisciplinary Journal of Nonlinear Science
Y1  - 2008
U6  - http://dx.doi.org/10.1063/1.2966112
SN  - 1089-7682
VL  - 18
IS  - 3
SP  - 033119
ER  - 
TY  - JOUR
A1  - Albracht, Kirsten
A1  - Arampatzis, A.
A1  - Baltzopoulos, V.
T1  - Assessment of muscle volume and physiological cross-sectional area of the human triceps surae muscle in vivo
JF  - Journal of Biomechanics
Y1  - 2008
U6  - http://dx.doi.org/10.1016/j.jbiomech.2008.04.020
SN  - 0021-9290
VL  - 41
SP  - 2211
EP  - 2218
ER  - 
TY  - JOUR
A1  - Ciobanu, Octavian
A1  - Staat, Manfred
A1  - Rahimi, Alireza
T1  - The use of open source software in biomechanical finite element analysis
JF  - Buletinul Institutului Politehnic din Iaşi / Universitatea Tehnică Gh. Asachi, Iaşi Secţia 5, Construcţii de maşini = Machine construction = Bulletin of the Polytechnic Institute of Jassy = Izvestija Jasskogo Politechničeskogo Instituta
Y1  - 2008
SN  - 1011-2855
VL  - 54
IS  - 7/8
SP  - 213
EP  - 220
ER  - 
TY  - JOUR
A1  - Ziemons, Karl
A1  - Bruyndonckx, P.
A1  - Perez, J. M.
A1  - Pietrzyk, U.
A1  - Rato, P.
A1  - Tavernier, S.
T1  - Beyond ClearPET: Next Aims
JF  - 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro Symposium Proceedings ISBI 2008
N2  - The CRYSTAL CLEAR collaboration, in short CCC, is a consortium of 12 academic institutions, mainly from Europe, joining efforts in the area of developing instrumentation for nuclear medicine and medical imaging. In the framework of the CCC a high performance small animal PET system, called ClearPET, was developed by using new technologies in electronics and crystals in a phoswich arrangement combining two types of lutetium- based scintillator materials: LSO:Ce and LuYAP:Ce. Our next aim will be the development of hybrid image systems. Hybrid MR-PET imaging has many unique advantages for brain research. This has sparked a new research line within CCC for the development of novel MR-PET compatible technologies. MRI is not as sensitive as PET but PET has poorer spatial resolution than MRI. Two major advantages of PET are sensitivity and its ability to acquire metabolic information. To assess these innovations, the development of a 9.4T hybrid animal MR-PET scanner is proposed based on an existing 9.4T MR scanner that will be adapted to enable simultaneous acquisition of MR and PET data using cutting- edge technology for both MR and PET.
Y1  - 2008
SN  - 978-1-4244-2003-2
SP  - 1421
EP  - 1424
ER  - 
TY  - JOUR
A1  - Streun, M.
A1  - Beer, S.
A1  - Hombach, T.
A1  - Jahnke, S.
A1  - Khodaverdi, M.
A1  - Larue, H.
A1  - Minwuyelet, S.
A1  - Parl, C.
A1  - Roeb, G.
A1  - Schurr, U.
A1  - Ziemons, Karl
T1  - PlanTIS: A positron emission tomograph for imaging 11C transport in plants
JF  - 2007 IEEE Nuclear Science Symposium Conference Record, Vol. 6
N2  - Plant growth and transport processes are highly dynamic. They are characterized by plant-internal control processes and by strong interactions with the spatially and temporally varying environment. Analysis of structure- function relations of growth and transport in plants will strongly benefit from the development of non-invasive techniques. PlanTIS (Plant Tomographic Imaging System) is designed for non-destructive 3D-imaging of positron emitting radiotracers. It will permit functional analysis of the dynamics of carbon distribution in plants including bulky organs. It will be applicable for screening transport properties of plants to evaluate e.g. temperature adaptation of genetically modified plants. PlanTIS is a PET scanner dedicated to monitor the dynamics of the 11C distribution within a plant while or after assimilation of 11CO2. Front end electronics and data acquisition architecture of the scanner are based on the ClearPETTM system [1]. Four detector modules form one of two opposing detector blocks. Optionally, a hardware coincidence detection between the blocks can be applied. In general the scan duration is rather long (~ 1 hour) compared to the decay time of 11C (20 min). As a result the count rates can vary over a wide range and accurate dead time correction is necessary.
Y1  - 2008
SN  - 1082-3654
SP  - 4110
EP  - 4112
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Digel, Ilya
A1  - Linder, Peter
A1  - Porst, Dariusz
T1  - Mechanism of haemoglobin sensing body temperature
JF  - Tissue Engineering Part A. 14 (2008), H. 5
Y1  - 2008
SN  - 1937-3341
N1  - TERMIS EU 2008 Porto Meeting June 22–26, 2008 Porto Congress Center–Alfândega Portugal
SP  - 754
EP  - 754
ER  - 
TY  - JOUR
A1  - Stadler, Andreas M.
A1  - Zerlin, Kay
A1  - Digel, Ilya
A1  - Büldt, Georg
A1  - Zaccai, Guiseppe
A1  - Artmann, Gerhard
T1  - Dynamics and interactions of hemoglobin in red blood cells
JF  - Tissue Engineering Part A. 14 (2008), H. 5
Y1  - 2008
SN  - 1937-3341
N1  - TERMIS EU 2008 Porto Meeting June 22–26, 2008 Porto Congress Center–Alfândega Portugal
SP  - 724
EP  - 724
ER  - 
TY  - JOUR
A1  - Digel, Ilya
A1  - Kayser, Peter
A1  - Artmann, Gerhard
T1  - Molecular processes in biological thermosensation
JF  - Journal of Biophysics. 2008 (2008)
Y1  - 2008
SN  - 1687-8000
SP  - 1
EP  - 9
ER  - 
TY  - JOUR
A1  - Stadler, Andreas M.
A1  - Embs, Jan P.
A1  - Digel, Ilya
A1  - Artmann, Gerhard
A1  - Unruh, Tobias
A1  - Büldt, Georg
A1  - Zaccai, Guiseppe
T1  - Cytoplasmic water and hydration layer dynamics in human red blood cells
JF  - Journal of the American Chemical Society. 50 (2008), H. 130
Y1  - 2008
SN  - 1520-5126
SP  - 16852
EP  - 16853
ER  - 
TY  - JOUR
A1  - Digel, Ilya
T1  - Controlling microbial adhesion : a surface engineering approach
JF  - Bioengineering in Cell and Tissue Research / Artmann, Gerhard M. ; Chien, Shu (Eds.)
Y1  - 2008
SN  - 978-3-540-75408-4
SP  - 601
EP  - 625
PB  - Springer
CY  - Berlin [u.a.]
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Lanzl, Ines M.
A1  - Maier, Mathias
A1  - Feucht, Nikolaus
T1  - Intraocular pressure effects of pegaptanib (macugen) injections in patients with and without glaucoma / Lanzl, Ines M. ; Maier, Mathias ; Feucht, Nikolaus ; Lohmann, Chris P. ; Kotliar, Konstantin E.
JF  - American Journal of Ophthalmology . 145 (2008), H. 1
Y1  - 2008
SN  - 1879-1891
SP  - 185
EP  - 185
PB  - -
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Mogilevskiĭ, A. Ia.
A1  - Shilo, A. V.
A1  - Panchekha, A. P.
T1  - [Chaotic non-linear dynamics of alpha-band of the EEg and organization of the cortical activity of P300 wave] / Mogilevskiĭ, A. Ia. ; Kotliar, K. E. ; Shilo, A. V. ; Panchekha, A. P.
JF  - Zhurnal vyssheĭ nervnoĭ deiatelnosti imeni I P Pavlova. 58 (2008), H. 5
Y1  - 2008
SN  - 0044-4677
N1  - Original in Russisch ; English abstract
SP  - 562
EP  - 575
PB  - -
ER  - 
TY  - JOUR
A1  - Nurispahic, A.
A1  - Kotliar, Konstantin
A1  - Lanzl, I.
T1  - Messung der Akkommodation mittels optischer Biometrie
JF  - Der Ophthalmologe
Y1  - 2008
SN  - 1433-0423
VL  - 105
IS  - 4
SP  - 369
EP  - 375
PB  - -
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Maier, Mathias
A1  - Bauer, Svetlana
A1  - Feucht, Nikolaus
A1  - Lohmann, Chris
A1  - Lanzl, Ines
T1  - Intravitreal injection of triamcinolone acetonide and intraocular pressure: author's reply
JF  - Acta Ophthalmologica
Y1  - 2008
SN  - 1755-3768
VL  - 86
IS  - 6
SP  - 692
EP  - 693
PB  - -
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Nagel, Edgar
A1  - Vilser, Walthard
A1  - Lanzl, Ines M.
T1  - Functional in vivo assessment of retinal artery microirregularities in glaucoma / Kotliar, Konstantin E. ; Nagel, Edgar ; Vilser, Walthard ; Lanzl, Ines M.
JF  - Acta Ophthalmologica. 86 (2008), H. 4
Y1  - 2008
SN  - 1755-3768
SP  - 424
EP  - 433
PB  - -
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Mücke, Bruno
A1  - Vilser, Walthard
A1  - Schilling, Rudolf
T1  - Effect of aging on retinal artery blood column diameter measured along the vessel axis / Kotliar, Konstantin E. ; Mücke, Bruno ; Vilser, Walthard ; Schilling, Rudolf ; Lanzl, Ines M.
JF  - Investigative Ophthalmology & Visual Science, IOVS. 49 (2008), H. 5
Y1  - 2008
SN  - 0146-0404
SP  - 2094
EP  - 2102
PB  - -
ER  - 
TY  - JOUR
A1  - Behbahani, Mehdi
A1  - Waluga, C.
A1  - Arlt, S.
A1  - Behr, M.
A1  - Mottaghy, K.
T1  - Computational Analysis of Platelet Aggregation in a Taylor-Couette System
JF  - The International Journal of Artificial Organs. 31 (2008), H. 7
Y1  - 2008
SN  - 0391-3988
N1  - Posterpresentation ; European Society of Artificial Organs (ESAO), Geneva, Switzerland
SP  - 643
ER  - 
TY  - JOUR
A1  - Behbahani, Mehdi
A1  - Behr, Marek
A1  - Nicolai, Mike
A1  - Probst, Markus
T1  - Towards Shape Optimization for Ventricular Assist Devices Using Parallel Stabilized FEM
JF  - NIC Symposium 2008 : symposium, 20 - 21 February 2008, Forschungszentrum Jülich ; proceedings / organized by John von Neumann Institute for Computing. Ed. by Gernot Münster; Dietrich Wolf; Manfred Kremer (ed.)
Y1  - 2008
SN  - 978-3-9810843-5-1
N1  - NIC series ; 39
SP  - 325
EP  - 332
PB  - Forschungszentrum
CY  - Jülich
ER  -