TY - JOUR A1 - Ziemons, Karl A1 - Auffray, Etiennette A1 - Barbier, R. A1 - Brandenburg, G. T1 - The ClearPET TM LSO/LuYAP phoswich scanner: a high performance small animal PET system JF - 2003 IEEE Nuclear Science Symposium Conference Record, Vol. 3 N2 - A 2nd generation high performance small animal PET scanner, called ClearPET™, has been designed and a first prototype is built by working groups of the Crystal Clear Collaboration (CCC). In order to achieve high sensitivity and maintain good uniform spatial resolution over the field of view in high resolution PET systems, it is necessary to extract the depth of interaction (DOI) information and correct for spatial degradation. The design of the first ClearPET™ Demonstrator based on the use of the multi-anode photomultiplier tube (Hamamatsu R7600-M64) and a LSO/LuYAP phoswich matrix. The two crystal layers of 8*8 crystals (2*2*10 mm3) are stacked on each other and mounted without light guide as one to one on the PMT. A unit of four PMTs arranged in-line represents one of 20 sectors of the ring design. The opening diameter of the crystal ring is 137 mm, the axial detector length is 110 mm. The PMT pulses are digitized by free-running ADCs and digital data processing determines the gamma energy, the phoswich layer and even the pulse arrival time. Single gamma interactions are recorded and coincidences are found by software. The gantry allows rotation of the detector modules around the field of view. The measurements have been done using the first LSO/LuYAP detector cassettes. Y1 - 2004 SN - 1082-3654 SP - 1728 EP - 1732 ER - TY - JOUR A1 - Khodaverdi, M. A1 - Chaziioannou, A. F. A1 - Weber, S. A1 - Ziemons, Karl A1 - Halling, H. A1 - Pietrzyk, U. T1 - Investigation of different microCT scanner configurations by GEANT4 simulations JF - 2003 IEEE Nuclear Science Symposium Conference Record, Vol. 4 N2 - This study has been performed to design the combination of the new ClearPET TM (ClearPET is a trademark of the Crystal Clear Collaboration), a small animal Positron Emission Tomography (PET) system, with a microComputed Tomography (microCT) scanner. The properties of different microCT systems have been determined by simulations based on GEANT4. We demonstrate the influence of the detector material and the X-ray spectrum on the obtained contrast. Four different detector materials (selenium, cadmium zinc telluride, cesium iodide and gadolinium oxysulfide) and two X-ray spectra (a molybdenum and a tungsten source) have been considered. The spectra have also been modified by aluminum filters of varying thickness. The contrast between different tissue types (water, air, brain, bone and fat) has been simulated by using a suitable phantom. The results indicate the possibility to improve the image contrast in microCT by an optimized combination of the X-ray source and detector material. Y1 - 2004 SN - 1082-3654 SP - 2989 EP - 2993 ER - TY - JOUR A1 - Digel, Ilya A1 - Zhubanova, Azhar A. A1 - Nojima, H. A1 - Artmann, Gerhard T1 - The use of bactericidal effects of cluster ions generated by plasma in medical biotechnology JF - Biotechnologija : teorija i praktika (2004) Y1 - 2004 SN - 1028-9399 SP - 46 EP - 52 ER - TY - JOUR A1 - Digel, Ilya A1 - Temiz Artmann, Aysegül A1 - Nishikawa, K. A1 - Artmann, Gerhard T1 - Cluster air-ion effects on bacteria and moulds JF - Biomedizinische Technik. 49 (2004), H. Erg.-Bd. 2 Y1 - 2004 SN - 0932-4666 SP - 1040 EP - 1041 ER - TY - JOUR A1 - Digel, Ilya A1 - Demirci, Taylan A1 - Temiz Artmann, Aysegül A1 - Nishikawa, K. T1 - Free Radical Nature of the Bactericidal Effect of Plasma-Generated Cluster Ions (PCIs) JF - Biomedizinische Technik. 49 (2004), H. Erg.-Bd. 2 Y1 - 2004 SN - 0932-4666 SP - 982 EP - 983 ER - TY - JOUR A1 - Digel, Ilya A1 - Trzewik, Jürgen A1 - Demirci, Taylan A1 - Temiz Artmann, Aysegül T1 - Response of fibroblasts to cyclic mechanical stress : a proteome approach / Digel, I. ; Trzewik, J. ; Demirci, T. ; Temiz Artmann, A. ; Artmann, G. M. JF - Biomedizinische Technik. 49 (2004), H. Erg.-Bd. 2 Y1 - 2004 SN - 0932-4666 SP - 1042 EP - 1043 ER - TY - JOUR A1 - Trzewik, Jürgen A1 - Temiz Artmann, Aysegül A1 - Linder, Peter A1 - Demirci, T. A1 - Digel, Ilya A1 - Artmann, Gerhard T1 - Evaluation of lateral mechanical tension in thin-film tissue constructs JF - Annals of Biomedical Engineering. 32 (2004), H. 9 Y1 - 2004 SN - 1573-9686 SP - 1243 EP - 1251 ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Svetlova, O. V. A1 - Stegaev, V. A. A1 - Parkhomov, S. D. T1 - Biomechanical substantiation of relatively low efficiency of recurrent laser trabeculoplasty / Svetlova, O. V. ; Stagaev, V. A. ; Parkhomov, S. D. ; Kotliar, K. E. ; Makarov, F. N. ; Smolnikov, B. A. ; Koshitz, I. N. JF - Glaukoma (2004) Y1 - 2004 N1 - Original in Russisch SP - 29 EP - 39 PB - - ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Svetlova, O. V. A1 - Sourjikov, A. V. A1 - Zaseeva, M. V. T1 - Biomechanical peculiarities of aqueous humor production system and outflow regulation system / Svetlova, O. V. ; Sourjikov, A. V. ; Kotliar, K. E. ; Zaseeva, M. V. ; Shukhaev, S. V. ; Koshitz, I. N. JF - Glaukoma (2004) Y1 - 2004 N1 - Original in Russisch SP - 66 EP - 76 PB - - ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Vilser, Walthatd A1 - Nagel, Edgar A1 - Lanzl, Ines M. T1 - Retinal vessel reaction in response to chromatic flickering light / Kotliar, Konstantin E. ; Vilser, Walthard ; Nagel, Edgar ; Lanzl, Ines M. JF - Graefe's Archive for Clinical and Experimental Ophthalmology. 242 (2004), H. 5 Y1 - 2004 SN - 1435-702X SP - 377 EP - 392 PB - - ER - TY - JOUR A1 - Weber, Hans-Joachim A1 - Hekmat, K. A1 - Zimmermann, T. A1 - Kampe, S. T1 - Impact of tranexamic acid vs. aprotinin on blood loss and transfusion requirements after cardiopulmonary bypass: a prospective, randomised, double-blind trial / Hekmat, K. ; Zimmermann, T. ; Kampe, S. ; Kasper, S. M. ; Weber, H. J. ; Geissler, H. J. ; Meh JF - Current Medical Research and Opinion. 20 (2004), H. 1 Y1 - 2004 SN - 0300-7995 SP - 121 EP - 126 ER - TY - JOUR A1 - Weber, Hans-Joachim A1 - Bhuju, S. A1 - Chandra, S. A1 - Mo, X. T1 - Fabrication of biodegradable nanofibers for tubular scaffolds in regenerative medicine / Weber, H.-J. ; Bhuju, S. ; Chandra, S. ; Mo, X. JF - Biomedizinische Technik. 49 (2004), H. Erg.-Bd. 2, Teil 2 Y1 - 2004 SP - 1016 EP - 1017 ER - TY - JOUR A1 - Kraft, Bodo A1 - Nobisrath, Ulrich A1 - Salumaa, Priit A1 - Schultchen, Erhard T1 - Fujaba based Tool Development for eHome Systems / Nobisrath, Ulrich ; Salumaa, Priit ; Schultchen, Erhard ; Kraft, Bodo JF - Electronic Notes in Theoretical Computer Science. 127 (2004), H. 1 Y1 - 2004 SN - 1571-0661 N1 - Proceedings of the International Workshop on Graph-Based Tools (GraBaTs 2004) SP - 89 EP - 99 ER - TY - JOUR A1 - Grotendorst, Johannes A1 - Kless, A. A1 - Dickhaus, T. A1 - Meyer, W. T1 - Data Mining in der pharmazeutischen Forschung und Entwicklung / Kless, A. ; Dickhaus, T. ; Meyer, W. ; Grotendorst, J. JF - LITUS - Laboratory IT User Service. 1 (2004) Y1 - 2004 SP - 20 EP - 21 ER - TY - JOUR A1 - Grotendorst, Johannes A1 - Kless, A. A1 - Eitrich, T. T1 - Data Mining in F & E / Kless, A. ; Eitrich, T. ; Meyer, W. ; Grotendorst, J. JF - BioWorld: Magazin für Molekularbiologische und Biotechnologische Applikationen. 9 (2004), H. 2 Y1 - 2004 SN - 1424-8514 SP - 22 EP - 23 ER - TY - JOUR A1 - Grotendorst, Johannes A1 - Scott, Tony C. A1 - Aubert-Frécon, Monique A1 - Hadinger, Gisèle T1 - Asymptotically exact calculation of the exchange energies of one-active-electron diatomic ions with the surface integral method / Scott, Tony C. ; Aubert-Frécon, Monique ; Hadinger, Gisèle ; Andrae, Dirk ; Grotendorst, Johannes ; Morgan Ill, John D. JF - Journal of Physics B: Atomic, Molecular and Optival Physics. 37 (2004), H. 22 Y1 - 2004 SN - 0953-4075 SP - 4451 EP - 4469 ER - TY - JOUR A1 - Grotendorst, Johannes A1 - Scott, Tony C. A1 - Aubert-Frécon, Monique A1 - Andrae, D. A1 - Morgan III, J. D. A1 - Glasser, M. L. T1 - Exchange Energy for Two-Active-Electron Diatomic Systems within the Surface Integral Method / Scott,T. C .; Aubert-Frécon, M. ; Andrae, D. ; Grotendorst, J. ; Morgan III, J. D. ; Glasser, M. L. JF - Applicable Algebra in Engineering, Communication and Computing. 15 (2004), H. 2 Y1 - 2004 SN - 0938-1279 N1 - zugl. Technical Report FZJ-ZAM-IB-2004-02, April 2004, 24 pages SP - 101 EP - 128 ER - TY - BOOK A1 - Grotendorst, Johannes T1 - High performance computing in chemistry : report of the joint research project: High Performance Computing in Chemistry - HPC-Chem ; funded by the Federal Ministry for Education and Research (BMBF) ; period: 1 March 2001 - 29 February 2004 / ed. by Johannes Grotendorst Y1 - 2004 SN - 3-00-013618-5 N1 - NIC-Serie ; 25 ; John von Neumann Institute for Computing PB - NIC CY - Jülich ER - TY - JOUR A1 - Demirci, T. A1 - Trzewik, J. A1 - Linder, Peter A1 - Digel, Ilya A1 - Artmann, Gerhard A1 - Temiz Artmann, Aysegül T1 - Mechanical Stimulation of 3T3 Fibroblasts Activates Genes: ITGB5 and p53 Responses as Quantified on the mRNA Level JF - Biomedizinische Technik . 49 (2004), H. Erg.-Bd. 2 Y1 - 2004 SN - 0932-4666 SP - 1030 EP - 1031 ER - TY - JOUR A1 - Demirci, T. A1 - Trzewik, J. A1 - Linder, Peter A1 - Artmann, Gerhard A1 - Temiz Artmann, Aysegül T1 - Mechanical Stimulation of 3T3 Fibroblasts Activates Genes: Real Time PCR Products and Suppliers by Comparison JF - Biomedizinische Technik . 49 (2004), H. Erg.-Bd. 2 Y1 - 2004 SN - 0932-4666 SP - 1046 EP - 1047 ER -