TY - CHAP A1 - Gömmel, Andreas A1 - Krämer, Sebastian A1 - Butenweg, Christoph A1 - Kob, Malte T1 - A combined FE and multiple-mass model for numerical simulation of phonatory maneuvers T2 - Proceedings / Forum Acusticum, Budapest, 29 Aug - 2 Sep, 2005 : [Acoustics: science and technology for knowledge based society and healthy environment] / ed. by: Fülöp Augusztinovicz ... Y1 - 2005 SN - 978-963-8241-68-9 SP - 2759 EP - 2764 PB - OPAKFI Tud. Egyesület CY - Budapest ER - TY - CHAP A1 - Kalker, Ines A1 - Neumann, M. A1 - Butenweg, Christoph A1 - Holler, Stefan T1 - Modelling of textile strengthened masonry T2 - Proceedings of the Tenth International Conference on Civil, Structural and Environmental Engineering Computing : [Rome, Italy, 30. August - 2. September 2005] / ed. by B. H. V. Topping Y1 - 2005 SN - 1-905088-00-0 U6 - https://doi.org/10.4203/ccp.81.184 SP - 447 EP - 448 PB - Civil-Comp Press CY - Stirling ER - TY - CHAP A1 - Altay, Okyay A1 - Taddei, Francesca A1 - Butenweg, Christoph A1 - Klinkel, Sven T1 - Vibration mitigation of wind turbine towers with tuned mass dampers T2 - Wind turbine control and monitoring. (Advances in industrial control) N2 - Because of its minor environmental impact, electricity generation using wind power is getting remarkable. The further growth of the wind industry depends on technological solutions to the challenges in production and construction of the turbines. Wind turbine tower vibrations, which limit power generation efficiency and cause fatigue problems with high maintenance costs, count as one of the main structural difficulties in the wind energy sector. To mitigate tower vibrations auxiliary measures are necessary. The effectiveness of tuned mass damper is verified by means of a numeric study on a 5 MW onshore reference wind turbine. Hereby, also seismic-induced vibrations and soil–structure interaction are considered. Acquired results show that tuned mass damper can effectively reduce resonant tower vibrations and improve the fatigue life of wind turbines. This chapter is also concerned with tuned liquid column damper and a semiactive application of it. Due to its geometric versatility and low prime costs, tuned liquid column dampers are a good alternative to other damping measures, in particular for slender structures like wind turbines. Y1 - 2014 SN - 978-3-319-08412-1 (Print) ; 978-3-319-08413-8 (E-Book) U6 - https://doi.org/10.1007/978-3-319-08413-8_12 SP - 337 EP - 373 PB - Springer CY - Cham ; Heidelberg ; New York ; Dordrecht ; London ER - TY - CHAP A1 - Grunendahl, A. A1 - de Rochefort, E. A1 - Butenweg, Christoph T1 - Numerical models for investigating the causes of low back pain due to whole-body vibrations T2 - 2nd International Conference on Computational Bioengineering : Lisbon, September 14-16 2005. Volume 2. Y1 - 2005 SN - 978-972-8469-37-3 SP - 905 EP - 914 PB - IST Press CY - Lisbon ER - TY - CHAP A1 - Renault, Philippe A1 - Butenweg, Christoph A1 - Mistler, Michael T1 - Seismic vulnerability assessment system for bridges T2 - Proceedings of the Tenth International Conference on Civil, Structural and Environmental Engineering Computing : [Rome, Italy, 30. August - 2. September 2005] / ed. by B. H. V. Topping Y1 - 2005 SN - 1-905088-00-0 SP - 1 EP - 14 PB - Civil-Comp Press CY - Stirling ER - TY - CHAP A1 - Mistler, Michael A1 - Butenweg, Christoph T1 - A seismic design procedure for masonry buildings T2 - Proceedings of the Tenth International Conference on Civil, Structural and Environmental Engineering Computing : [Rome, Italy, 30. August - 2. September 2005] / ed. by B. H. V. Topping Y1 - 2005 SN - 1-905088-00-0 U6 - https://doi.org/10.4203/ccp.81.193 SP - 465 EP - 467 PB - Civil-Comp Press CY - Stirling ER - TY - CHAP A1 - Karimi, Iman A1 - Butenweg, Christoph A1 - Toll, Britta T1 - Vulnerability assessment of industrial facilities T2 - Proceedings of the Tenth International Conference on Civil, Structural and Environmental Engineering Computing : [Rome, Italy, 30. August - 2. September 2005] / ed. by B. H. V. Topping Y1 - 2005 SN - 1-905088-00-0 U6 - https://doi.org/10.4203/ccp.81.34 SP - 34, 73 EP - 75 PB - Civil-Comp Press CY - Stirling ER - TY - CHAP A1 - Kalker, Ines A1 - Toll, B. A1 - Holler, Stefan A1 - Butenweg, Christoph A1 - Topping, B. H. V. A1 - Mota Soares, C. A. T1 - Capacity analysis of textile retrofitted unreinforced masonry T2 - Proceedings of the Seventh International Conference on Computational Structures Technology : [Lisbon, Portugal, 7 - 9 September 2004] / ed. by B. H. V. Topping ... Y1 - 2004 SN - 0-948749-95-4 U6 - https://doi.org/10.4203/ccp.79.194 SP - 431 EP - 432 PB - Civil-Comp Press CY - Stirling ER - TY - CHAP A1 - Kob, Malte A1 - Butenweg, Christoph T1 - A finite element model of the interaction between intra-and extralaryngeal muscles T2 - International Conference on Voice Physiology and Biomechanics, August 18-20, 2004, Marseille, France Y1 - 2004 SP - 1 EP - 2 ER - TY - CHAP A1 - Kremers, Alexander A1 - Pieper, Martin T1 - Simulation and Verification of Bionic Heat Exchangers with COMSOL Multiphysics® Software T2 - COMSOL Conference 2015 User Presentations ; COMSOL Conference 2015 Grenoble October 14 - 16, 2015 - World Trade Center, Grenoble, France Y1 - 2015 PB - COMSOL CY - Göttingen ; Berlin ER - TY - CHAP A1 - Dalguer, Luis A. A1 - Renault, Philippe A1 - Churilov, Sergey A1 - Butenweg, Christoph T1 - Evaluation of fragility curves for a three-storey-reinforced-concrete mock-up of SMART 2013 project T2 - Transactions, SMiRT-23 : 23rd Conference on Structural Mechanics in Reactor Technology : Manchester, United Kingdom - August 10-14, 2015 Y1 - 2016 SP - 1 EP - 9 ER - TY - CHAP A1 - Kuhlmann, Wolfram A1 - Butenweg, Christoph A1 - Lopez, Marijen A1 - Fernandez, Sebastian T1 - Seismic vulnerability assessment of the historic Aachen Cathedral T2 - Conference proceedings / 13th World Conference on Earthquake Engineering [Vancouver, British Columbia, Canada, August 1 - 6, 2004] / [hosted by CAEE/ACGP, Canadian Association for Earthquake Engineering] Y1 - 2004 SP - 1 EP - 14 PB - CAEE CY - Vancouver ER - TY - CHAP A1 - Meskouris, Konstantin A1 - Butenweg, Christoph A1 - Mistler, Michael A1 - Kuhlmann, Wolfram T1 - Seismic behaviour of historic masonry buildings T2 - 7th National Congress on Mechanics : Chania, Crete, June 24 - 26, 2004 ; proceedings / ed. A. Kounadis .... Y1 - 2004 SP - 47 EP - 49 PB - Hellenic Society for Theoretical and Applied Mechanics CY - Chania ER - TY - CHAP A1 - Konrad, M. A1 - Chudoba, Rostislav A1 - Butenweg, Christoph A1 - Bruckermann, O. T1 - Textile reinforced concrete. Part II: Multi-level modeling concept T2 - Digital proceedings / IKM 2003, proceedings 16th International Conference on the Applications of Computer Science and Mathematics in Architecture and Civil Engineering [Elektronische Ressource : 10. - 12. Juni 2003, Weimar] / Bauhaus-Universität Weimar. Ed.: K. Gürlebeck; L. Hempel; C. Könke Y1 - 2003 SP - 1 EP - 11 PB - IKM CY - Weimar ER - TY - CHAP A1 - Chudoba, Rostislav A1 - Butenweg, Christoph A1 - Pfeiffer, Frank T1 - Textile reinforced concrete. Part I: Process model for collaborative research and development T2 - Digital proceedings / IKM 2003, proceedings 16th International Conference on the Applications of Computer Science and Mathematics in Architecture and Civil Engineering [Elektronische Ressource : 10. - 12. Juni 2003, Weimar] / Bauhaus-Universität Weimar. Ed.: K. Gürlebeck; L. Hempel; C. Könke Y1 - 2003 SP - 1 EP - 8 PB - IKM CY - Weimar ER - TY - JOUR A1 - Dikta, Gerhard A1 - Reißel, Martin A1 - Harlaß, Carsten T1 - Semi-parametric survival function estimators deduced from an identifying Volterra type integral equation JF - Journal of multivariate analysis N2 - Based on an identifying Volterra type integral equation for randomly right censored observations from a lifetime distribution function F, we solve the corresponding estimating equation by an explicit and implicit Euler scheme. While the first approach results in some known estimators, the second one produces new semi-parametric and pre-smoothed Kaplan–Meier estimators which are real distribution functions rather than sub-distribution functions as the former ones are. This property of the new estimators is particular useful if one wants to estimate the expected lifetime restricted to the support of the observation time. Specifically, we focus on estimation under the semi-parametric random censorship model (SRCM), that is, a random censorship model where the conditional expectation of the censoring indicator given the observation belongs to a parametric family. We show that some estimated linear functionals which are based on the new semi-parametric estimator are strong consistent, asymptotically normal, and efficient under SRCM. In a small simulation study, the performance of the new estimator is illustrated under moderate sample sizes. Finally, we apply the new estimator to a well-known real dataset. KW - Volterra integral equation KW - Product-integration KW - Asymptotic efficiency KW - Semi-parametric random censorship model KW - Censored data KW - Survival analysis Y1 - 2016 U6 - https://doi.org/10.1016/j.jmva.2016.02.008 IS - 147 SP - 273 EP - 284 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Jung, Alexander A1 - Staat, Manfred A1 - Müller, Wolfram T1 - Effect of wind on flight style optimisation in ski jumping T2 - 15th International Symposium on Computer Simulation in Biomechanics ; July 9th-11th 2015, Edinburgh, UK Y1 - 2016 SP - 53 EP - 54 PB - The University of Edinburgh ; Loughborough University CY - Edinburgh ER - TY - JOUR A1 - Frotscher, Ralf A1 - Muanghong, Danita A1 - Dursun, Gözde A1 - Goßmann, Matthias A1 - Temiz Artmann, Aysegül A1 - Staat, Manfred T1 - Sample-specific adaption of an improved electro-mechanical model of in vitro cardiac tissue JF - Journal of Biomechanics N2 - We present an electromechanically coupled computational model for the investigation of a thin cardiac tissue construct consisting of human-induced pluripotent stem cell-derived atrial, ventricular and sinoatrial cardiomyocytes. The mechanical and electrophysiological parts of the finite element model, as well as their coupling are explained in detail. The model is implemented in the open source finite element code Code_Aster and is employed for the simulation of a thin circular membrane deflected by a monolayer of autonomously beating, circular, thin cardiac tissue. Two cardio-active drugs, S-Bay K8644 and veratridine, are applied in experiments and simulations and are investigated with respect to their chronotropic effects on the tissue. These results demonstrate the potential of coupled micro- and macroscopic electromechanical models of cardiac tissue to be adapted to experimental results at the cellular level. Further model improvements are discussed taking into account experimentally measurable quantities that can easily be extracted from the obtained experimental results. The goal is to estimate the potential to adapt the presented model to sample specific cell cultures. KW - hiPS cardiomyocytes KW - Homogenization KW - Hodgkin–Huxley models KW - Frequency adaption KW - Electromechanical modeling KW - Drug simulation KW - Computational biomechanics KW - Cardiac tissue Y1 - 2016 U6 - https://doi.org/10.1016/j.jbiomech.2016.01.039 SN - 0021-9290 (Print) SN - 1873-2380 (Online) VL - 49 IS - 12 SP - 2428 EP - 2435 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Goßmann, Matthias A1 - Frotscher, Ralf A1 - Linder, Peter A1 - Bayer, Robin A1 - Epple, U. A1 - Staat, Manfred A1 - Temiz Artmann, Aysegül A1 - Artmann, Gerhard T1 - Mechano-pharmacological characterization of cardiomyocytes derived from human induced pluripotent stem cells JF - Cellular physiology and biochemistry N2 - Background/Aims: Common systems for the quantification of cellular contraction rely on animal-based models, complex experimental setups or indirect approaches. The herein presented CellDrum technology for testing mechanical tension of cellular monolayers and thin tissue constructs has the potential to scale-up mechanical testing towards medium-throughput analyses. Using hiPS-Cardiac Myocytes (hiPS-CMs) it represents a new perspective of drug testing and brings us closer to personalized drug medication. Methods: In the present study, monolayers of self-beating hiPS-CMs were grown on ultra-thin circular silicone membranes and deflect under the weight of the culture medium. Rhythmic contractions of the hiPS-CMs induced variations of the membrane deflection. The recorded contraction-relaxation-cycles were analyzed with respect to their amplitudes, durations, time integrals and frequencies. Besides unstimulated force and tensile stress, we investigated the effects of agonists and antagonists acting on Ca²⁺ channels (S-Bay K8644/verapamil) and Na⁺ channels (veratridine/lidocaine). Results: The measured data and simulations for pharmacologically unstimulated contraction resembled findings in native human heart tissue, while the pharmacological dose-response curves were highly accurate and consistent with reference data. Conclusion: We conclude that the combination of the CellDrum with hiPS-CMs offers a fast, facile and precise system for pharmacological, toxicological studies and offers new preclinical basic research potential. KW - Inotropic compounds KW - Pharmacology KW - Ion channels KW - CellDrum KW - Heart tissue culture KW - Induced pluripotent stem cells KW - Cardiac myocytes Y1 - 2016 U6 - https://doi.org/10.1159/000443124 SN - 1421-9778 (Online) SN - 1015-8987 (Print) VL - 38 IS - 3 SP - 1182 EP - 1198 PB - Karger CY - Basel ER - TY - CHAP A1 - Funke, Harald A1 - Keinz, Jan A1 - Haj Ayed, A. A1 - Kazari, M. A1 - Kitajima, J. A1 - Horikawa, A. A1 - Okada, K. T1 - Development and Testing of a Low NOx Micromix Combustion Chamber for an Industrial Gas Turbine T2 - Proceedings of International Gas Turbine Congress 2015 Tokyo November 15-20, 2015, Tokyo, Japan Y1 - 2015 SN - 978-4-89111-008-6 N1 - IGTC15-0092 SP - 131 EP - 140 ER -