TY - JOUR A1 - Guo, Yuanyuan A1 - Seki, Kosuke A1 - Miyamoto, Ko-ichiro A1 - Wagner, Torsten A1 - Schöning, Michael Josef A1 - Yoshinobu, Tatsuo T1 - Device simulation of the light-addressable potentiometric sensor with a novel photoexcitation method for a higher spatial resolution JF - Procedia Engineering N2 - A novel photoexcitation method for the light-addressable potentiometric sensor (LAPS) realized a higher spatial resolution of chemical imaging. In this method, a modulated light probe, which generates the alternating photocurrent signal, is surrounded by a ring of constant light, which suppresses the lateral diffusion of photocarriers by enhancing recombination. A device simulation verified that a higher spatial resolution could be obtained by adjusting the gap between the modulated and constant light. It was also found that a higher intensity and a longer wavelength of constant light was more effective. However, there exists a tradeoff between the spatial resolution and the amplitude of the photocurrent, and thus, the signal-to-noise ratio. A tilted incidence of constant light was applied, which could achieve even higher resolution with a smaller loss of photocurrent. KW - Light-addressable Potentiometric Sensor KW - novel photoexcitation method KW - tilted constant illumination KW - spatial resolution Y1 - 2014 U6 - https://doi.org/10.1016/j.proeng.2014.11.369 SN - 1877-7058 N1 - EUROSENSORS 2014 ; European Conference on Solid-State Transducers <28, 2014> VL - 87 SP - 456 EP - 459 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Miyamoto, K. A1 - Seki, K. A1 - Wagner, Torsten A1 - Schöning, Michael Josef A1 - Yoshinobu, T. T1 - Enhancement of the spatial resolution of the chemical imaging sensor by a hybrid fiber-optic illumination JF - Procedia Engineering N2 - The chemical imaging sensor, which is based on the principle of the light-addressable potentiometric sensor (LAPS), is a powerful tool to visualize the spatial distribution of chemical species on the sensor surface. The spatial resolution of this sensor depends on the diffusion of photocarriers excited by a modulated light. In this study, a novel hybrid fiber-optic illumination was developed to enhance the spatial resolution. It consists of a modulated light probe to generate a photocurrent signal and a ring of constant light, which suppresses the lateral diffusion of minority carriers excited by the modulated light. It is demonstrated that the spatial resolution was improved from 92 μm to 68 μm. Y1 - 2014 U6 - https://doi.org/10.1016/j.proeng.2014.11.563 SN - 1877-7058 N1 - EUROSENSORS 2014 ; European Conference on Solid-State Transducers <28, 2014> VL - 87 SP - 612 EP - 615 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Werner, Frederik A1 - Yoshinobu, T. A1 - Miyamoto, K. A1 - Schöning, Michael Josef A1 - Wagner, Torsten T1 - Semiconductor-based sensors for imaging of chemical processes T2 - Sensoren und Messsysteme 2014 ; Beiträge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in Nürnberg. (ITG-Fachbericht ; 250) Y1 - 2014 SN - 978-3-8007-3622-5 SP - 1 EP - 5 PB - VDE-Verl. CY - Düsseldorf ER - TY - CHAP A1 - Oberländer, Jan A1 - Kirchner, Patrick A1 - Keusgen, M. A1 - Schöning, Michael Josef T1 - Flexible polyimide-based calorimetric gas sensors for monitoring hy-drogen peroxide in sterilisation processes of aseptic filling machines T2 - Sensoren und Messsysteme 2014 ; Beiträge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in Nürnberg. (ITG-Fachbericht ; 250) Y1 - 2014 SN - 978-3-8007-3622-5 SP - 1 EP - 4 PB - VDE-Verl. CY - Düsseldorf ER - TY - CHAP A1 - Voronkova, Eva B. A1 - Bauer, Svetlana M. A1 - Kotliar, Konstantin T1 - Computer simulation of the cornea-scleral shell as applied to pressure-volume relationship in the human eye T2 - 2014 International Conference on Computer Technologies in Physical and Engineering Applications : ICCTPEA 2014 : proceedings : June 30 2014-July 4 2014, St. Petersburg Y1 - 2014 SN - 978-1-4799-5315-8 SP - 204 EP - 205 ER - TY - THES A1 - Reyes Ochoa, Leonel T1 - Engineering aspects of a parabolic trough collector field with direct steam generation and an organic rankine cycle Y1 - 2014 N1 - Aachen, Fachhochsch., Masterarbeit, 2014 PB - Fachhochschule Aachen CY - Aachen ER - TY - JOUR A1 - Almajhdi, Fahad N. A1 - Senger, Tilo A1 - Amer, Haitham M. A1 - Gissmann, Lutz A1 - Öhlschläger, Peter T1 - Design of a highly effective therapeutic HPV16 E6/E7-specific DNA vaccine: optimization by different ways of sequence rearrangements (Shuffling) JF - PLOS one N2 - Persistent infection with the high-risk Human Papillomavirus type 16 (HPV 16) is the causative event for the development of cervical cancer and other malignant tumors of the anogenital tract and of the head and neck. Despite many attempts to develop therapeutic vaccines no candidate has entered late clinical trials. An interesting approach is a DNA based vaccine encompassing the nucleotide sequence of the E6 and E7 viral oncoproteins. Because both proteins are consistently expressed in HPV infected cells they represent excellent targets for immune therapy. Here we report the development of 8 DNA vaccine candidates consisting of differently rearranged HPV-16 E6 and E7 sequences within one molecule providing all naturally occurring epitopes but supposedly lacking transforming activity. The HPV sequences were fused to the J-domain and the SV40 enhancer in order to increase immune responses. We demonstrate that one out of the 8 vaccine candidates induces very strong cellular E6- and E7- specific cellular immune responses in mice and, as shown in regression experiments, efficiently controls growth of HPV 16 positive syngeneic tumors. This data demonstrates the potential of this vaccine candidate to control persistent HPV 16 infection that may lead to malignant disease. It also suggests that different sequence rearrangements influence the immunogenecity by an as yet unknown mechanism. Y1 - 2014 U6 - https://doi.org/10.1371/journal.pone.0113461 SN - 1932-6203 VL - 11 IS - 9 PB - PLOS CY - San Francisco ER - TY - BOOK A1 - Kern, Alexander A1 - Wettingfeld, Jürgen T1 - Blitzschutzsysteme 1 : allgemeine Grundsätze, Risikomanagement, Schutz von baulichen Anlagen und Personen ; Erläuterungen zu den Normen DIN EN 62305-1 (VDE 0185-305-1):2011-10, DIN EN 62305-2 (VDE 0185-305-2):2013-02, DIN EN 62305-3 (VDE 0185-305-3):2011-10. (VDE-Schriftenreihe Normen verständlich ; 44) Y1 - 2014 SN - 978-3-8007-3511-2 PB - VDE-Verl. CY - Berlin [u.a.] ER - TY - BOOK A1 - Tietze, Jürgen T1 - Übungsbuch zur angewandten Wirtschaftsmathematik : Aufgaben, Testklausuren und ausführliche Lösungen. - 9., überarb. u. erw. Aufl. Y1 - 2014 SN - 978-3-658-06874-5 ; 978-3-658-06873-8 PB - Vieweg + Teubner CY - Wiesbaden ET - 9., überarb. u. erw. Aufl. ER - TY - JOUR A1 - Wollert, Jörg T1 - Funkstandards für Sensornetzwerke JF - Elektronik : Fachmedium für industrielle Anwender und Entwickler Y1 - 2014 SN - 0013-5658 VL - Bd. 63 IS - H. 12 SP - 36 EP - 41 PB - WEKA-Fachmedien CY - Haar ER - TY - JOUR A1 - Wollert, Jörg T1 - Echtzeit-Ethernet : Protokoll-Reigen JF - Elektronik : Fachmedium für industrielle Anwender und Entwickler Y1 - 2014 SN - 0013-5658 VL - Bd. 63 IS - H. 26 SP - 24 EP - 31 PB - WEKA-Fachmedien CY - Haar ER - TY - JOUR A1 - Wollert, Jörg T1 - Der Embedded Wireless-Report JF - Elektronik : Fachmedium für industrielle Anwender und Entwickler ; Sonderh. Wireless : Fachmedium für Entwicklungen funkbasierter Systeme Y1 - 2014 SN - 0013-5658 SP - 18 EP - 25 PB - WEKA-Fachmedien CY - Haar ER - TY - JOUR A1 - Wollert, Jörg T1 - Echtzeit-Ethernet mit Standardtechnik JF - Elektronik : Fachmedium für industrielle Anwender und Entwickler ; Sonderh. Embedded : Fachmagazin für die Entwicklung von Embedded-Systemen Y1 - 2014 SN - 0013-5658 VL - Bd. 63 IS - H. 12 SP - 28 EP - 32 PB - WEKA-Fachmedien CY - Haar ER - TY - CHAP A1 - Huber, Max A1 - Rau, Sebastian A1 - Streblow, Rita A1 - Wollert, Jörg A1 - Müller, Dirk T1 - Lüftungskanäle als Funkstrecke T2 - Jahreskolloquium Kommunikation in der Automation (KommA 2014) : Lemgo, 18.11.2014 / Jürgen Jasperneite ... (Hrsg.) Y1 - 2014 SN - 978-3-9814062-4-5 SP - 1 EP - 8 ER - TY - JOUR A1 - Wollert, Jörg T1 - Feldbustechnologie JF - Factory : der Durchblick in der Technik Y1 - 2014 SP - Publ. online PB - WEKA-Industriemedien CY - Wien ER - TY - JOUR A1 - Demny, Andreas A1 - Hebel, Christoph T1 - Rechnergestützte Ermittlung der Verbindungsfunktionsstufen und der verbindungsbezogenen Angebotsqualität nach den Richtlinien für integrierte Netzgestaltung nach RIN 2008 JF - Straßenverkehrstechnik : Organ der Forschungsgesellschaft für Straßen- und Verkehrswesen, der Bundesvereinigung der Straßenbau- und Verkehrsingenieure und der Österreichischen Forschungsgesellschaft Straße und Verkehr ; Zeitschrift für Verkehrsplanung, Verkehrsmanagement, Verkehrssicherheit, Verkehrstechnik Y1 - 2014 SN - 0039-2219 VL - Jg. 58 IS - H. 12 SP - 811 EP - 820 PB - Kirschbaum Verlag CY - Bonn ER - TY - CHAP A1 - Hebel, Christoph T1 - Mehrwert T2 - Unser Dorf hat Zukunft Y1 - 2014 SP - 6 EP - 7 PB - StädteRegion Aachen CY - Aachen ER - TY - CHAP A1 - Fateri, Miranda A1 - Gebhardt, Andreas T1 - Jewelry fabrication via selective laser melting of glass T2 - ASME 2014 12th Biennial Conference on Engineering Systems Design and Analysis Volume 1: Applied Mechanics; Automotive Systems; Biomedical Biotechnology Engineering; Computational Mechanics; Design; Digital Manufacturing; Education; Marine and Aerospace Applications N2 - Selective Laser Melting (SLM) is one of the Additive Manufacturing (AM) technologies applicable for producing complex geometries which are typically expensive or difficult to fabricate using conventional methods. This process has been extensively investigated experimentally for various metals and the fabrication process parameters have been established for different applications; however, fabricating 3D glass objects using SLM technology has remained a challenge so far although it could have many applications. This paper presents a summery on various experimental evaluations of a material database incorporating the build parameters of glass powder using the SLM process for jewelry applications. Y1 - 2014 SN - 978-0-7918-4583-7 U6 - https://doi.org/10.1115/ESDA2014-20380 SP - V001T06A005 ER - TY - CHAP A1 - Benner, Joachim T1 - Berechnungsmethoden der Wälzlagerreibung und Einflussgrößen T2 - SMK 2014 : Schweizer Maschinenelemente Kolloquim 25. und 26. November 2014 Y1 - 2014 SN - 978-3-944331-81-2 SP - 151 EP - 170 PB - TUDpress Verl. der Wissenschaften CY - Dresden ER - TY - JOUR A1 - Thomas, Axel T1 - Generation Y JF - P.T. : Magazin für Wirtschaft und Gesellschaft Y1 - 2014 SN - 1860-501X VL - 10 IS - 3 SP - 6 EP - 9 PB - OPS Netzwerk CY - Leipzig ER -