TY  - JOUR
A1  - Müller-Veggian, Mattea
A1  - Conte, V.
A1  - Colautti, P.
A1  - De Nardo, L.
T1  - Microdosimetric spectra down to 70 nm
JF  - Annual report / Istituto Nazionale di Fisica Nucleare, LNL, Laboratori Nazionali di Legnaro. 1997 (1998)
Y1  - 1998
N1  - Nebent.: Annual Report LNL-INFN
SP  - 67
EP  - 68
ER  - 
TY  - JOUR
A1  - Temiz Artmann, Aysegül
A1  - Ates, H.
A1  - Üretmen, Ö.
A1  - Andac, K.
T1  - Erythrocyte deformability in high-tension and normal tension glaucoma. Ates, H.; Üretmen, Ö.; Temiz, A.; Andac, K.
JF  - International Ophthalmology. 22 (1998), H. 1
Y1  - 1998
SN  - 0165-5701
SP  - 7
EP  - 12
ER  - 
TY  - JOUR
A1  - Temiz Artmann, Aysegül
A1  - Baskurt, O. K.
A1  - Meiselman, H. J.
T1  - Effect of superoxide anions on red blood cell rheologic properties. Baskurt, O. K.; Temiz, A.; Meiselman, H. J.
JF  - Free Radical Biology and Medicine. 24 (1998), H. 1
Y1  - 1998
SN  - 0891-5849
SP  - 102
EP  - 110
ER  - 
TY  - JOUR
A1  - Weckesser, Martin
A1  - Grießmeier, Martin
A1  - Schmidt, Daniela
A1  - Sonnenberg, Frank
A1  - Ziemons, Karl
A1  - Kemna, Lars
A1  - Holschbach, Marcus
A1  - Langen, Karl-J.
A1  - Müller-Gärtner, Hans-W.
T1  - Iodine-123 α-methyl tyrosine single-photon emission tomography of cerebral gliomas: standardised evaluation of tumour uptake and extent
JF  - European Journal of Nuclear Medicine
N2  - Single-photon emission tomography (SPET) with the amino acid analogue l-3-[123I]iodo-α-methyl tyrosine (IMT) is helpful in the diagnosis and monitoring of cerebral gliomas. Radiolabelled amino acids seem to reflect tumour infiltration more specifically than conventional methods like magnetic resonance imaging and computed tomography. Automatic tumour delineation based on maximal tumour uptake may cause an overestimation of mean tumour uptake and an underestimation of tumour extension in tumours with circumscribed peaks. The aim of this study was to develop a program for tumour delineation and calculation of mean tumour uptake which takes into account the mean background activity and is thus optimised to the problem of tumour definition in IMT SPET. Using the frequency distribution of pixel intensities of the tomograms a program was developed which automatically detects a reference brain region and draws an isocontour region around the tumour taking into account mean brain radioactivity. Tumour area and tumour/brain ratios were calculated. A three-compartment phantom was simulated to test the program. The program was applied to IMT SPET studies of 20 patients with cerebral gliomas and was compared to the results of manual analysis by three different investigators. Activity ratios and chamber extension of the phantom were correctly calculated by the automatic analysis. A method based on image maxima alone failed to determine chamber extension correctly. Manual region of interest analysis in patient studies resulted in a mean inter-observer standard deviation of 8.7%±6.1% (range 2.7%–25.0%). The mean value of the results of the manual analysis showed a significant correlation to the results of the automatic analysis (r = 0.91, P<0.0001 for the uptake ratio; r = 0.87, P<0.0001 for the tumour area). We conclude that the algorithm proposed simplifies the calculation of uptake ratios and may be used for observer-independent evaluation of IMT SPET studies. Three-dimensional tumour recognition and transfer to co-registered morphological images based on this program may be useful for the planning of surgical and radiation treatment.
Y1  - 1998
SN  - 1619-7089
VL  - 25
IS  - 2
SP  - 150
EP  - 156
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Kelemen, C.
A1  - Porst, Dariusz
A1  - Büldt, G.
T1  - Cellular engineering: Crash tests an menschlichen Erythrozyten geben Aufschluß über versteckte Materialeigenschaften zellulärer Proteine / Artmann, G. M. ; Kelemen, Ch. ; Porst, D. ; Büldt, G. ; Chien, Shu
JF  - Biomedizinische Technik / Biomedical Engineering. 43 (1998), H. s1
Y1  - 1998
SN  - 1862-278
SP  - 446
EP  - 447
ER  - 
TY  - JOUR
A1  - Dikta, Gerhard
T1  - On Semiparametric Random Censorship Models
JF  - Journal of Statistical Planning and Inference. 66 (1998), H. 2
Y1  - 1998
SN  - 0378-3758
SP  - 253
EP  - 279
ER  - 
TY  - JOUR
A1  - Stulpe, Werner
A1  - Bugajski, S.
A1  - Hellwig, K.-E.
T1  - On Fuzzy Random Variables and Statistical Maps. Bugajski, S.; Hellwig, K.-E.; Stulpe, W.
JF  - Reports on Mathematical Physics. 41 (1998), H. 1
Y1  - 1998
SN  - 0034-4877
SP  - 1
EP  - 11
ER  - 
TY  - JOUR
A1  - Stulpe, Werner
T1  - On the Representation of Quantum Mechanics on a Classical Sample Space
JF  - International Journal of Theoretical Physics. 37 (1998), H. 1
Y1  - 1998
SN  - 1572-9575
SP  - 349
EP  - 356
ER  - 
TY  - JOUR
A1  - Stulpe, Werner
A1  - Ruch, Ernst
T1  - Proof of the Mixing Theorem for Statistical Systems in Classical Physics. Ruch, Ernst; Stulpe, Werner
JF  - Acta Applicandae Mathematicae. 53 (1998), H. 3
Y1  - 1998
SN  - 1572-9036
SP  - 329
EP  - 352
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Sung, K.-L. Paul
A1  - Horn, Thomas
A1  - Whittemore, Darren [u.a.]
T1  - Micropipette aspiration of human erythrocytes induces echinocytes via membrane phospholipid translocation. Artmann, Gerhard Michael; Sung, K.-L. Paul; Horn, Thomas; Whittemore, Darren; Norwich, Gerald; Chien, Shu
JF  - Biophysical journal. 72 (1997), H. 3
Y1  - 1997
SN  - 1542-0086
SP  - 1434
EP  - 1441
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Ronkel, F.
A1  - Crott, M.
A1  - Thust, M. (u.a.)
T1  - Miniaturization of potentiometric sensors using porous silicon microtechnology
JF  - Electrochimica Acta. 42 (1997), H. 22
Y1  - 1997
SN  - 0013-4686
SP  - 3185
EP  - 3193
ER  - 
TY  - JOUR
A1  - Schäfer, Horst
A1  - Worschech, L.
A1  - Ossau, W.
A1  - Fischer, C.
T1  - Characterization of structural defects in MBE grown ZnSe
JF  - Materials Science and Engineering B. 43 (1997), H. 1-3
Y1  - 1997
SN  - 0921-5107
N1  - Beitrag zum EMRS - Spring Meeting, 4.-7.06.1996 Strasbourg
SP  - 29
EP  - 32
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Schütz, S.
A1  - Riemer, A.
A1  - Weißbecker, B.
A1  - Steffen, A.
A1  - Kordos, P.
A1  - Lüth, H.
A1  - Hummel, Hans E.
T1  - A BioFET on the basis of intact insect antennae
JF  - Proceedings of the 11th European Conference on Solid-State Transducers / Eurosensors XI, September 21 - 24, 1997, Warsaw, Poland. [Organised by] Warsaw University of Technology. Vol 2.
Y1  - 1997
SN  - 83-908335-0-6
N1  - Eurosensors ; (11, 1997, Warszawa) ; Eurosensors - European Conference on Solid-State Transducers ; (11 : ; 1997.09.21-24 : ; Warsaw)
SP  - 1461
EP  - 1464
PB  - Sensor Lab Sp.
CY  - Warsaw
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Weidenbrück, B.
A1  - Thust, M.
A1  - Kordos, P.
A1  - Lüth, H.
T1  - A silicon-based sensor array with capacitive EIS structures
JF  - Proceedings of the 11th European Conference on Solid-State Transducers / Eurosensors XI, September 21 - 24, 1997, Warsaw, Poland. [Organised by] Warsaw University of Technology. Vol 2.
Y1  - 1997
SN  - 83-908335-0-6
N1  - Eurosensors ; (11, 1997, Warszawa) ; Eurosensors - European Conference on Solid-State Transducers ; (11 : ; 1997.09.21-24 : ; Warsaw)
SP  - 871
EP  - 874
PB  - Sensor Lab Sp.
CY  - Warsaw
ER  - 
TY  - JOUR
A1  - Glück, O.
A1  - Schöning, Michael Josef
A1  - Lüth, H.
A1  - Emons, H.
A1  - Hanewinkel, C.
A1  - Schumacher, D.
A1  - Otto, A.
T1  - Trace metal determination with gold microelectrodes fabricated by silicon technology
JF  - Proceedings of the 11th European Conference on Solid-State Transducers / Eurosensors XI, September 21 - 24, 1997, Warsaw, Poland. [Organised by] Warsaw University of Technology. Vol 2.
Y1  - 1997
SN  - 83-908335-0-6
N1  - Eurosensors ; (11, 1997, Warszawa) ; Eurosensors - European Conference on Solid-State Transducers ; (11 : ; 1997.09.21-24 : ; Warsaw)
SP  - 615
EP  - 618
PB  - Sensor Lab Sp.
CY  - Warsaw
ER  - 
TY  - JOUR
A1  - Ackermann, Hans-Josef
T1  - Morphing- und Level-of-Detail-Techniken zur Reduzierung des Darstellungsaufwands bei Echtzeit-Sichtsimulationen
JF  - Digital controls for high resolution display : JESSI Europrojekt No. 3203000, AE-36 ; Abschlußbericht ; Laufzeit u. Berichtszeitraum: 01.01.1995 bis 31.12.1996.
Y1  - 1997
CY  - Erlangen
ER  - 
TY  - JOUR
A1  - Müller-Veggian, Mattea
A1  - Colautti, P.
A1  - Schröder, M.
A1  - Tornielli, G.
T1  - Electric field Gradient Effects in TEPS
JF  - Annual report / Istituto Nazionale di Fisica Nucleare, LNL, Laboratori Nazionali di Legnaro. 1996 (1997)
Y1  - 1997
N1  - Nebent.: Annual Report LNL-INFN
SP  - 253
EP  - 254
ER  - 
TY  - JOUR
A1  - Temiz Artmann, Aysegül
A1  - Baskurt, O. K.
A1  - Meiselman, H. J.
T1  - Red blood cell aggregation in experimental sepsis . Baskurt, O. K.; Temiz, A.; Meiselman, H. J.
JF  - Journal of Laboratory and Clinical Medicine. 130 (1997), H. 2
Y1  - 1997
SN  - 0022-2143
SP  - 183
EP  - 190
ER  - 
TY  - JOUR
A1  - Langen, Karl J.
A1  - Ziemons, Karl
A1  - Kiwit, Jürgen C. W.
A1  - Herzog, Hans
A1  - Kuwert, Torsten
A1  - Bock, Wolfgang
A1  - Stöcklin, Gerhard
A1  - Feinendegen, Ludwig E.
A1  - Müller-Gärtner, Hans-W.
T1  - 3-[123I]iodo-α-methyltyrosine and [methyl-11C]-L-methionine uptake in cerebral gliomas: a compara-tive study using SPECT and PET
JF  - Journal of Nuclear Medicine
Y1  - 1997
SN  - 0161-5505
VL  - 38
IS  - 4
SP  - 517
EP  - 522
ER  - 
TY  - JOUR
A1  - Weckesser, Matthias
A1  - Hufnagel, Andreas
A1  - Ziemons, Karl
A1  - Grießmeier, Martin
A1  - Sonnenberg, Frank
A1  - Hackländer, Thomas
A1  - Langen, Karl-J.
A1  - Holschbach, Markus
A1  - Elger, Christian E.
A1  - Müller-Gärtner, Hans-W.
T1  - Effect of partial volume correction on muscarinic cholinergic receptor imaging with single-photon emission tomography in patients with temporal lobe epilepsy
JF  - European Journal of Nuclear Medicine
N2  - Animal experiments and preliminary results in humans have indicated alterations of hippocampal muscarinic acetylcholine receptors (mAChR) in temporal lobe epilepsy. Patients with temporal lobe epilepsy often present with a reduction in hippocampal volume. The aim of this study was to investigate the influence of hippocampal atrophy on the quantification of mAChR with single photon emission tomography (SPET) in patients with temporal lobe epilepsy. Cerebral uptake of the muscarinic cholinergic antagonist [123I]4-iododexetimide (IDex) was investigated by SPET in patients suffering from temporal lobe epilepsy of unilateral (n=6) or predominantly unilateral (n=1) onset. Regions of interest were drawn on co-registered magnetic resonance images. Hippocampal volume was determined in these regions and was used to correct the SPET results for partial volume effects. A ratio of hippocampal IDex binding on the affected side to that on the unaffected side was used to detect changes in muscarinic cholinergic receptor density. Before partial volume correction a decrease in hippocampal IDex binding on the focus side was found in each patient. After partial volume no convincing differences remained. Our results indicate that the reduction in hippocampal IDex binding in patients with epilepsy is due to a decrease in hippocampal volume rather than to a decrease in receptor concentration.
Y1  - 1997
SN  - 1619-7089
VL  - 24
IS  - 9
SP  - 1156
EP  - 1161
ER  -