TY  - JOUR
A1  - Iber, Michaela
A1  - Schübeler, Dirk
A1  - Seibler, Jost
A1  - Höxter, Maria
A1  - Bode, Jürgen
T1  - Efficient FACS selection procedure for cells undergoing Flp-mediated site-specific conversions
JF  - Technical Tips Online
Y1  - 1998
U6  - http://dx.doi.org/10.1016/S1366-2120(08)70132-6
VL  - 4
IS  - 1
SP  - 25
EP  - 29
ER  - 
TY  - JOUR
A1  - Bode, J.
A1  - Bartsch, J.
A1  - Boulikas, T.
A1  - Iber, M.
A1  - Mielke, C.
A1  - Schübeler, D.
A1  - Seibler, Jost
A1  - Benham, C.
T1  - Transcription-promoting genomic sites in mammalia: their elucidation and architectural principles
JF  - Gene therapy & molecular biology
Y1  - 1998
SN  - 1529-9120
VL  - 1
IS  - 1
SP  - 1
EP  - 29
ER  - 
TY  - JOUR
A1  - Seibler, Jost
A1  - Schübeler, Dirk
A1  - Fiering, Steven
A1  - Groudine, Mark
A1  - Bode, Jürgen
T1  - DNA cassette exchange in ES cells mediated by Flp recombinase: an efficient strategy for repeated modification of tagged loci by marker-free constructs
JF  - Biochemistry
Y1  - 1998
U6  - http://dx.doi.org/10.1021/bi980288t
SN  - 1520-4995
VL  - 37
IS  - 18
SP  - 6229
EP  - 6234
ER  - 
TY  - JOUR
A1  - Pohl, Martina
A1  - Siegert, Petra
A1  - Mesch, K.
A1  - Bruhn, H.
A1  - Grötzinger, Joachim
T1  - Active site mutants of pyruvate decarboxylase from Zymomonas mobilis : a site-directed mutagenesis study of L112, I472, I476, E473 and N482
JF  - European journal of biochemistry
Y1  - 1998
SN  - 1432-1033 (E-Journal); 1742-4658 (E-Journal); 0014-2956 (Print); 1742-464X (Print)
VL  - Vol. 257
IS  - Iss. 3
SP  - 538
EP  - 546
ER  - 
TY  - JOUR
A1  - Iding, Hans
A1  - Siegert, Petra
A1  - Mesch, K.
A1  - Pohl, Martina
T1  - Application of α-keto acid decarboxylases in biotransformations
JF  - Biochimica et biophysica acta (BBA) - Protein structure and molecular enzymology
Y1  - 1998
SN  - 1879-2588 (E-Journal); 0167-4838 (Print)
VL  - Vol. 1385
IS  - Iss. 2
SP  - 307
EP  - 322
ER  - 
TY  - JOUR
A1  - Zientz, Evelyn
A1  - Bongaerts, Johannes
A1  - Unden, Gottfried
T1  - Fumarate regulation of gene expression in Escherichia coli by the DcuSR (dcuSR genes) two-component regulatory system
JF  - Journal of bacteriology
Y1  - 1998
SN  - 1098-5530 (E-Journal); 0021-9193 (Print)
VL  - Vol. 180
IS  - No. 20
SP  - 5421
EP  - 5425
ER  - 
TY  - JOUR
A1  - Meliß, Michael
A1  - Neskakis, A.
A1  - Plettner-Marliani, J.
A1  - Lange, C.
A1  - Hövelmann, A.
A1  - Schumacher, J.
T1  - Waste water recycling supplied by renewable energies : basic conditions and possible treatment technologies
JF  - Renewable energy. Vol. 14 (1998), iss. 1-4. 6th Arab International Solar Energy Conference: Bringing Solar Energy into the Daylight, Muscat, Sultanate of Oman, 29.03.-01.04.1998
Y1  - 1998
SN  - 1879-0682 (E-Book); 0960-1481 (Print)
SP  - 325
EP  - 331
ER  - 
TY  - JOUR
A1  - Weckesser, Martin
A1  - Grießmeier, Martin
A1  - Schmidt, Daniela
A1  - Sonnenberg, Frank
A1  - Ziemons, Karl
A1  - Kemna, Lars
A1  - Holschbach, Marcus
A1  - Langen, Karl-J.
A1  - Müller-Gärtner, Hans-W.
T1  - Iodine-123 α-methyl tyrosine single-photon emission tomography of cerebral gliomas: standardised evaluation of tumour uptake and extent
JF  - European Journal of Nuclear Medicine
N2  - Single-photon emission tomography (SPET) with the amino acid analogue l-3-[123I]iodo-α-methyl tyrosine (IMT) is helpful in the diagnosis and monitoring of cerebral gliomas. Radiolabelled amino acids seem to reflect tumour infiltration more specifically than conventional methods like magnetic resonance imaging and computed tomography. Automatic tumour delineation based on maximal tumour uptake may cause an overestimation of mean tumour uptake and an underestimation of tumour extension in tumours with circumscribed peaks. The aim of this study was to develop a program for tumour delineation and calculation of mean tumour uptake which takes into account the mean background activity and is thus optimised to the problem of tumour definition in IMT SPET. Using the frequency distribution of pixel intensities of the tomograms a program was developed which automatically detects a reference brain region and draws an isocontour region around the tumour taking into account mean brain radioactivity. Tumour area and tumour/brain ratios were calculated. A three-compartment phantom was simulated to test the program. The program was applied to IMT SPET studies of 20 patients with cerebral gliomas and was compared to the results of manual analysis by three different investigators. Activity ratios and chamber extension of the phantom were correctly calculated by the automatic analysis. A method based on image maxima alone failed to determine chamber extension correctly. Manual region of interest analysis in patient studies resulted in a mean inter-observer standard deviation of 8.7%±6.1% (range 2.7%–25.0%). The mean value of the results of the manual analysis showed a significant correlation to the results of the automatic analysis (r = 0.91, P<0.0001 for the uptake ratio; r = 0.87, P<0.0001 for the tumour area). We conclude that the algorithm proposed simplifies the calculation of uptake ratios and may be used for observer-independent evaluation of IMT SPET studies. Three-dimensional tumour recognition and transfer to co-registered morphological images based on this program may be useful for the planning of surgical and radiation treatment.
Y1  - 1998
SN  - 1619-7089
VL  - 25
IS  - 2
SP  - 150
EP  - 156
ER  - 
TY  - JOUR
A1  - Kleines, H.
A1  - Ziemons, Karl
A1  - Zwoll, K.
T1  - Experiences with ATM in a multivendor pilot system at Forschungszentrum Jülich
JF  - IEEE Transactions on Nuclear Science
N2  - The ATM technology for high speed serial transmission provides a new quality of communication by introducing novel features in a LAN environment, especially support of real time communication, of both LAN and WAN communication and of multimedia streams. In order to evaluate ATM for future DAQ systems and remote control systems as well as for a high speed picture archiving and communications system for medical images, Forschungszentrum Julich has build up a pilot system for the evaluation of ATM and standard low cost multimedia systems. It is a heterogeneous multivendor system containing a variety of switches and desktop solutions, employing different protocol options of ATM. The tests conducted in the pilot system revealed major difficulties regarding stability, interoperability and performance. The paper presents motivations, layout and results of the pilot system. Discussion of results concentrates on performance issues relevant for realistic applications, e.g., connection to a RAID system via NFS over ATM
Y1  - 1998
SN  - 0018-9499
VL  - 45
IS  - 4
SP  - 1867
EP  - 1871
ER  - 
TY  - JOUR
A1  - Havermann, Marc
A1  - Beylich, A. E.
T1  - Combined Measurement of Velocity, Temperature and Pressure in Compressible Gas Flows Using Laser-Induced Iodine Fluorescence / Havermann, M. ; Beylich, A. E.
Y1  - 1998
N1  - 9th International Symposium on Applications of Laser Techniques to Fluid Mechanics, Lisbon (Portugal), 1998
PB  - -
ER  - 
TY  - JOUR
A1  - Wolf, Martin
A1  - Simon, S.
A1  - Schlick, Christopher
T1  - Qualitative and Quantitative Analysis of Cooperation / Wolf, M. ; Simon, S. ; Schlick, C.
JF  - Proceedings : May 26 - 29, 1998, Cannes (France) = Actes : 26 - 29 mai 1998 / INRIA, Institut National de Recherche en Informatique et en Automatique, Unité de recherche ... F. Darses ..., eds
Y1  - 1998
N1  - COOP ; Institut National de Recherche en Informatique et en Automatique ; Centre ; (Sophia Antipolis) ; International Conference on the Design of Cooperative Systems ; (3 ; 1998.05.26-29 ; Cannes) ; Conference Internationale sur la Conception de Systèmes Coopératifs ; (3 ; 1998.05.26-29 ; Cannes) ; COOP ; (3 ; 1998.05.26-29 ; Cannes)
SP  - 1
EP  - 5
PB  - -
CY  - Cannes
ER  - 
TY  - JOUR
A1  - Kallweit, Stephan
A1  - Uchiyama, R.
A1  - Siekmann, H.
T1  - Fault Diagnostic Method for Pump Running Conditions Based on Process Modeling and Neural Network / Uchiyama, R. ; Kallweit, S. ; Siekmann, H.
JF  - International Journal of Rotating Machinery. 4 (1998), H. 1
Y1  - 1998
SN  - 1542-3034
SP  - 49
EP  - 59
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Kelemen, C.
A1  - Porst, Dariusz
A1  - Büldt, G.
T1  - Cellular engineering: Crash tests an menschlichen Erythrozyten geben Aufschluß über versteckte Materialeigenschaften zellulärer Proteine / Artmann, G. M. ; Kelemen, Ch. ; Porst, D. ; Büldt, G. ; Chien, Shu
JF  - Biomedizinische Technik / Biomedical Engineering. 43 (1998), H. s1
Y1  - 1998
SN  - 1862-278
SP  - 446
EP  - 447
ER  - 
TY  - JOUR
A1  - Enning, Manfred
A1  - Jenayeh, I.
A1  - Müller, C.
A1  - Kositza, N.
T1  - A New Approach for Automating Shunting Processes in Marshalling Yards / Jenayeh, I.;  Müller, C. ; Kositza, N. ; Enning, M. ; Rake, H.
JF  - Computational Engineering in Systems Applications : 2nd IMACS International Multiconference CESA'98; [abstracts; Nabeul-Hammamet, Tunisia, April 1 - 4, 1998] / ed. by Pierre Borne
Y1  - 1998
SP  - 338
EP  - 343
PB  - UCIS
CY  - Villeneuve d'Ascq
ER  - 
TY  - JOUR
A1  - Enning, Manfred
A1  - Jenayeh, I.
A1  - Müller, C.
A1  - Kositza, N.
T1  - Mechatronics in automating shunting processes in marshalling yards / Jenayeh, I. ; Müller, C.; Kositza, N. ; Enning, M. ; Rake, H.
JF  - Mechatronics  '98 : proceedings of the 6th UK Mechatronics Forum International Conference, Skövde, Sweden, 9-11 September 1998
Y1  - 1998
SN  - 0-08-043339-1
N1  - UK Mechatronics Forum International Conference (6 : 1998  : Skövde)
PB  - Pergamon
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Schuba, Marko
A1  - Reichl, Peter
A1  - Kesdogan, Dogan
A1  - Junghärtchen, Klaus
T1  - Simulative Performance Evaluation of the Temporary Pseudonym Method for Protecting Location Information in GSM Networks / Reichl, P. ; Kesdogan, D. ; Junghärtchen, K. ; Schuba, M.
JF  - Computer Performance Evaluation - Modelling Techniques and Tools / Puigjaner, Ramon (eds.)
Y1  - 1998
SN  - 3-540-64949-2
N1  - Lecture notes in computer  science ; 1469
SP  - 105
EP  - 116
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Schuba, Marko
T1  - SRMT-a scalable and reliable multicast transport protocol
JF  - IEEE International Conference on Communications, 1998. ICC 98. Vol. 1
Y1  - 1998
SN  - 0-7803-4788-9
SP  - 612
EP  - 616
ER  - 
TY  - JOUR
A1  - Schuba, Marko
A1  - Schneider, Gaby
A1  - Haverkort, Boudewijn R.
T1  - QNA-MC: A Performance Evaluation Tool for Communication Networks with Multicast Data Streams / Schneider, G. ; Schuba, M. ; Haverkort, B. R.
JF  - Computer Performance Evaluation - Modelling Techniques and Tools / Puigjaner, Ramon (eds.)
Y1  - 1998
SN  - 3-540-64949-2
N1  - Lecture notes in computer  science ; 1469
SP  - 105
EP  - 116
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Schuba, Marko
A1  - Reichl, Peter
T1  - On large-scale reliable multicast protocols / Schuba, M. ; Reichl, P.
JF  - 6th IEE Conference on Telecommunications
Y1  - 1998
SN  - 0-85296-700-4
N1  - Conf. Publ. No. 451
SP  - 133
EP  - 137
ER  - 
TY  - JOUR
A1  - Schuba, Marko
A1  - Reichl, Peter
T1  - An Analysis of Retransmission Strategies for Reliable Multicast Protocols / Schuba, M. ; Reichl, P.
JF  - Performance of information and communication systems : IFIP TC 6,WG 6.3 Seventh International Conference on Performance of Information and Communication Systems (PICS '98), 25 - 28 May, Lund, Sweden / ed. by Ulf Körner ...
Y1  - 1998
SN  - 0-412-83730-7
SP  - 1
EP  - 12
PB  - Chapman  Hall
CY  - London
ER  -