TY  - CHAP
A1  - Osterhage, Hannes
A1  - Bialonski, Stephan
A1  - Staniek, Matthäus
A1  - Schindler, Kaspar
A1  - Wagner, Tobias
A1  - Elger, Christian E.
A1  - Lehnertz, Klaus
T1  - Bivariate and multivariate time series analysis techniques and their potential impact for seizure prediction
T2  - Seizure Prediction in Epilepsy: From Basic Mechanisms to Clinical Applications
Y1  - 2008
SN  - 978-3-527-62519-2
U6  - https://doi.org/10.1002/9783527625192.ch15
SP  - 189
EP  - 208
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - CHAP
A1  - Pfetsch, Marc E.
A1  - Abele, Eberhard
A1  - Altherr, Lena
A1  - Bölling, Christian
A1  - Brötz, Nicolas
A1  - Dietrich, Ingo
A1  - Gally, Tristan
A1  - Geßner, Felix
A1  - Groche, Peter
A1  - Hoppe, Florian
A1  - Kirchner, Eckhard
A1  - Kloberdanz, Hermann
A1  - Knoll, Maximilian
A1  - Kolvenbach, Philip
A1  - Kuttich-Meinlschmidt, Anja
A1  - Leise, Philipp
A1  - Lorenz, Ulf
A1  - Matei, Alexander
A1  - Molitor, Dirk A.
A1  - Niessen, Pia
A1  - Pelz, Peter F.
A1  - Rexer, Manuel
A1  - Schmitt, Andreas
A1  - Schmitt, Johann M.
A1  - Schulte, Fiona
A1  - Ulbrich, Stefan
A1  - Weigold, Matthias
T1  - Strategies for mastering uncertainty
T2  - Mastering uncertainty in mechanical engineering
N2  - This chapter describes three general strategies to master uncertainty in technical systems: robustness, flexibility and resilience. It builds on the previous chapters about methods to analyse and identify uncertainty and may rely on the availability of technologies for particular systems, such as active components. Robustness aims for the design of technical systems that are insensitive to anticipated uncertainties. Flexibility increases the ability of a system to work under different situations. Resilience extends this characteristic by requiring a given minimal functional performance, even after disturbances or failure of system components, and it may incorporate recovery. The three strategies are described and discussed in turn. Moreover, they are demonstrated on specific technical systems.
Y1  - 2021
SN  - 978-3-030-78353-2
U6  - https://doi.org/10.1007/978-3-030-78354-9_6
N1  - Part of the Springer Tracts in Mechanical Engineering book series (STME)
SP  - 365
EP  - 456
PB  - Springer
CY  - Cham
ER  - 
TY  - CHAP
A1  - Pieronek, Lukas
A1  - Kleefeld, Andreas
ED  - Constanda, Christian
ED  - Harris, Paul
T1  - The Method of Fundamental Solutions for Computing Interior Transmission Eigenvalues of Inhomogeneous Media
T2  - Integral Methods in Science and Engineering: Analytic Treatment and Numerical Approximations
N2  - The method of fundamental solutions is applied to the approximate computation of interior transmission eigenvalues for a special class of inhomogeneous media in two dimensions. We give a short approximation analysis accompanied with numerical results that clearly prove practical convenience of our alternative approach.
Y1  - 2019
SN  - 978-3-030-16077-7
U6  - https://doi.org/10.1007/978-3-030-16077-7_28
SP  - 353
EP  - 365
PB  - Birkhäuser
CY  - Cham
ER  - 
TY  - CHAP
A1  - Pietsch, Wolfram
T1  - A framework for strategic positioning of IT-products
T2  - Software business : from physical products to software services and solutions : 4th International Conference on Software Business, ICSOB 2013; Potsdam; Germany; 11 June 2013 through 14 June 2013. (Lecture notes in business information processing ; 150)
N2  - IT Products are viewed and managed differently depending on the perspectives and the stage within the life cycle. A model is presented that integrates different perspectives and stages serving as an aid for the analysis of business models and focused positioning of IT-products. Four generic business models are analysed with regard to the product management function in general and the positioning field for IT-products specifically: off-the-shelf (license), license plus service, project, and system service (incl. cloud computing).
KW  - Strategic Business Planning
KW  - IT Products
KW  - Business Models
KW  - Product Management
Y1  - 2013
U6  - https://doi.org/10.1007/978-3-642-39336-5_11
SP  - 102
EP  - 116
PB  - Springer
CY  - Berlin
ER  - 
TY  - CHAP
A1  - Poghossian, Arshak
A1  - Schusser, Sebastian
A1  - Bäcker, M.
A1  - Leinhos, Marcel
A1  - Schöning, Michael Josef
T1  - Real-time in-situ electrical monitoring of the degradation of biopolymers using semiconductor field-effect devices
T2  - Biodegradable biopolymers. Vol. 1
Y1  - 2015
SN  - 978-1-63483-632-6
SP  - 135
EP  - 153
PB  - Nova Science Publ.
CY  - Hauppauge
ER  - 
TY  - CHAP
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
T1  - Nanomaterial-Modified Capacitive Field-Effect Biosensors
T2  - Springer Series on Chemical Sensors and Biosensors (Methods and Applications)
N2  - The coupling of charged molecules, nanoparticles, and more generally, inorganic/organic nanohybrids with semiconductor field-effect devices based on an electrolyte–insulator–semiconductor (EIS) system represents a very promising strategy for the active tuning of electrochemical properties of these devices and, thus, opening new opportunities for label-free biosensing by the intrinsic charge of molecules. The simplest field-effect sensor is a capacitive EIS sensor, which represents a (bio-)chemically sensitive capacitor. In this chapter, selected examples of recent developments in the field of label-free biosensing using nanomaterial-modified capacitive EIS sensors are summarized. In the first part, we present applications of EIS sensors modified with negatively charged gold nanoparticles for the label-free electrostatic detection of positively charged small proteins and macromolecules, for monitoring the layer-by-layer formation of oppositely charged polyelectrolyte (PE) multilayers as well as for the development of an enzyme-based biomolecular logic gate. In the second part, examples of a label-free detection by means of EIS sensors modified with a positively charged weak PE layer are demonstrated. These include electrical detection of on-chip and in-solution hybridized DNA (deoxyribonucleic acid) as well as an EIS sensor with pH-responsive weak PE/enzyme multilayers for enhanced field-effect biosensing.
KW  - Biomolecular logic gate
KW  - DNA
KW  - Enzyme biosensor
KW  - Field-effect sensor
KW  - Gold nanoparticle
Y1  - 2017
U6  - https://doi.org/10.1007/5346_2017_2
SP  - 1
EP  - 25
PB  - Springer
CY  - Berlin, Heidelberg
ER  - 
TY  - CHAP
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
T1  - Silicon-based chemical and biological field-effect sensors
T2  - Encyclopedia of Sensors. Vol. 9 S - Sk
Y1  - 2006
SN  - 1-58883-065-9
SP  - 463
EP  - 534
PB  - ASP, American Scientific Publ.
CY  - Stevenson Ranch, Calif.
ER  - 
TY  - CHAP
A1  - Poghossian, Arshak
A1  - Weiland, Maryam
A1  - Schöning, Michael Josef
ED  - Lvova, Larisa
ED  - Kirsanov, Dmitry
ED  - di Natale, Corrado
ED  - Legin, Audrey
T1  - Nanoplate field-effect capacitors: a new transducer structure for multiparameter (bio-)chemical sensing
T2  - Multisensor system for chemical analysis : materials and sensors
N2  - An array of electrically isolated nanoplate field-effect silicon-on-insulator (SOI) capacitors as a new transducer structure for multiparameter (bio-)chemical sensing is presented. The proposed approach allows addressable biasing and electrical readout of multiple nanoplate field-effect capacitive (bio-)chemical sensors on the same SOI chip, as well as differential-mode measurements. The realized sensor chip has been applied for pH and penicillin concentration measurements, electrical monitoring of polyelectrolyte multilayer formation, and the label-free electrical detection of consecutive deoxyribonucleic acid (DNA) hybridization and denaturation events.
Y1  - 2014
SN  - 978-981-4411-15-8 ; 978-981-4411-16-5
U6  - https://doi.org/10.1201/b15491-11
SP  - 333
EP  - 373
PB  - Jenny Stanford Publishing
CY  - Singapore
ET  - 1
ER  - 
TY  - CHAP
A1  - Priede, Gareth
A1  - Ferrein, Alexander
T1  - Towards passive walking for the fully-actuated biped robot Nao
T2  - Emerging trends in computing, informatics, systems sciences, and engineering. (Lecture notes in electrical engineering : vol. 151)
N2  - Many biped robots deploy a form of gait that follows the zero moment point (ZMP) approach, that is, the robot is in a stable position at any point in time. This requires the robot to be fully actuated. While very stable, the draw-backs of this approach are a fairly slow gait and high energy consumption. An alternative approach is the so-called passive-dynamic walking, where the gait makes use of the inertia and dynamic stability of the robot. In this paper we describe our ongoing work of combining the principles of passive-dynamic walking on the fully-actuated biped robot Nao, which is also deployed for robotic soccer applications. We present a simple controller that allows the robot to stably rock sidewards, showing a closed limit-cycle. We discuss first results of superimposing a forward motion on the sidewards motion. Based on this we expect to endow the Nao with a fast, robust, and stable passive-dynamic walk on the fully-actuated Nao in the future.
Y1  - 2013
SN  - 978-1-4614-3557-0 ; 978-1-4614-3558-7
U6  - https://doi.org/10.1007/978-1-4614-3558-7_18
SP  - 225
EP  - 236
PB  - Springer
CY  - New York, NY
ER  - 
TY  - CHAP
A1  - Pulini, Paola
A1  - Gligorevic, Snjezana
T1  - WIMAX performance in the airport environment
T2  - Multi-carrier systems & solutions 2009. (Lecture notes in electrical engineering ; 41)
N2  - In this paper, the multicarrier physical layers of WiMAX are evaluated in the context of airport data links. The orthogonal frequency-division multiplexing (OFDM) and orthogonal frequency-division multiple-access (OFDMA) cases are applied to the forward link (FL) and reverse link (RL), respectively. The performance of the so called parking and taxi scenarios is presented for airport communications in C-band. Numerical results show that the proposed scheme brings good performance for both the FL and the RL. For the OFDMA case a structure changing called double-tile is also proposed to improve the system performance.
Y1  - 2009
SN  - 978-90-481-2529-6 (Print) ; 978-90-481-2530-2 (Online)
SP  - 301
EP  - 310
PB  - Springer
CY  - Berlin [u.a.]
ER  - 
TY  - CHAP
A1  - Rahier, Michael
A1  - Ritz, Thomas
A1  - Wallenborn, Ramona
T1  - Information and communication technology for integrated mobility concepts such as E-carsharing
T2  - E-Mobility in Europe : trends and good practice
N2  - During the past decade attitude towards sharing things has changed extremely. Not just personal data is shared (e.g. in social networks) but also mobility. Together with the increased ecological awareness of the recent years, new mobility concepts have evolved. E-carsharing has become a symbol for these changes of attitude. The management of a shared car fleet, the energy management of electric mobility and the management of various carsharing users with individual likes and dislikes are just some of the major challenges of e-carsharing. Weaving it into integrated mobility concepts, this raises complexity even further. These challenges can only be overcome by an appropriate amount of well-shaped information available at the right place and time. In order to gather, process and share the required information, fleet cars have to be equipped with modern information and communication technology (ICT) and become so-called fully connected cars. Ensuring the usability of these ICT systems is another challenge that is often neglected, even though it is usability that makes carsharing comfortable, attractive and supports users’ new attitudes. By means of an integrated and consistent concept for human-machine interaction (HMI), the usability of such systems can be raised tremendously.
KW  - Information and communication technology
KW  - Fully connected car
KW  - E-carsharing
KW  - Mobility management
KW  - Integrated mobility
Y1  - 2015
SN  - 978-3-319-13193-1
U6  - https://doi.org/10.1007/978-3-319-13194-8_17
SP  - 311
EP  - 326
PB  - Springer
CY  - Cham [u.a.]
ER  - 
TY  - CHAP
A1  - Rao, Deepak
A1  - Pathrose, Plato
A1  - Hüning, Felix
A1  - Sid, Jithin
T1  - An Approach for Validating Safety of Perception Software in Autonomous Driving Systems
T2  - Model-Based Safety and Assessment: 6th International Symposium, IMBSA 2019, Thessaloniki, Greece, October 16–18, 2019, Proceedings
N2  - The increasing complexity of Advanced Driver Assistance Systems (ADAS) presents a challenging task to validate safe and reliable performance of these systems under varied conditions. The test and validation of ADAS/AD with real test drives, although important, involves huge costs and time. Simulation tools provide an alternative with the added advantage of reproducibility but often use ideal sensors, which do not reflect real sensor output accurately. This paper presents a new validation methodology using fault injection, as recommended by the ISO 26262 standard, to test software and system robustness. In our work, we investigated and developed a tool capable of inserting faults at different software and system levels to verify its robustness. The scope of this paper is to cover the fault injection test for the Visteon’s DriveCore™ system, a centralized domain controller for Autonomous driving which is sensor agnostic and SoC agnostic. With this new approach, the validation of safety monitoring functionality and its behavior can be tested using real-world data instead of synthetic data from simulation tools resulting in having better confidence in system performance before proceeding with in-vehicle testing.
KW  - Advanced driver assistance systems (ADAS/AD)
KW  - ISO 26262
KW  - Safety-critical systems validation
KW  - Safety of the intended functionality (SOTIF)
Y1  - 2019
SN  - 978-3-030-32872-6
U6  - https://doi.org/10.1007/978-3-030-32872-6_20
SP  - 303
EP  - 316
PB  - Springer
CY  - Cham
ER  - 
TY  - CHAP
A1  - Rebel, Sören
A1  - Hüning, Felix
A1  - Scholl, Ingrid
A1  - Ferrein, Alexander
T1  - MQOne: Low-cost design for a rugged-terrain robot platform
T2  - Intelligent robotics and applications : 8th International Conference, ICIRA 2015, Portsmouth, UK, August 24-27, 2015, Proceedings, Part II (Lecture notes in computer science : vol. 9245)
N2  - Rugged terrain robot designs are important for field robotics missions. A number of commercial platforms are available, however, at an impressive price. In this paper, we describe the hardware and software component of a low-cost wheeled rugged-terrain robot. The robot is based on an electric children quad bike and is modified to be driven by wire. In terms of climbing properties, operation time and payload it can compete with some of the commercially available platforms, but at a far lower price.
Y1  - 2015
SN  - 978-3-319-22875-4 (print) ; 978-3-319-22876-1 (E-Book)
U6  - https://doi.org/10.1007/978-3-319-22876-1_19
SP  - 209
EP  - 221
PB  - Springer
CY  - Cham
ER  - 
TY  - CHAP
A1  - Reimer, Lars
A1  - Braun, Carsten
A1  - Ballmann, Josef
T1  - Computational study of the aeroelastic equilibrium configuration of a swept wind tunnel wing model in subsonic flow
T2  - High performance computing in science and engineering '06. Transactions of the High Performance Computing Center Stuttgart (HLRS) 2006 /  Wolfgang E. Nagel ... Eds.
N2  - In the Collaborative Research Center SFB 401 at RWTH Aachen University, the numerical aeroelastic method SOFIA for direct numerical aeroelastic simulation is being progressively developed. Numerical results obtained by applying SOFIA were compared with measured data of static and dynamic aeroelastic wind tunnel tests for an elastic swept wing in subsonic flow.
Y1  - 2007
SN  - 978-3-540-36165-7
SP  - 421
EP  - 434
PB  - Springer
CY  - Berlin [u.a.]
ER  - 
TY  - CHAP
A1  - Reimer, Lars
A1  - Braun, Carsten
A1  - Wellmer, Georg
A1  - Behr, Marek
A1  - Ballmann, Josef
T1  - Development of a modular method for computational aero-structural analysis of aircraft
T2  - Summary of flow modulation and fluid-structure interaction findings. Results of the Collaborative Research Center SFB 401 at the RWTH Aachen University, Aachen, Germany, 1997-2008 / ed.: Wolfgang Schröder. Notes on numerical fluid mechanics and multidisciplinary design. Vol. 109
Y1  - 2010
SN  - 978-3-642-04087-0
SP  - 205
EP  - 238
PB  - Springer
CY  - Berlin
ER  - 
TY  - CHAP
A1  - Reimer, Lars
A1  - Wellmer, Georg
A1  - Braun, Carsten
A1  - Ballmann, Josef
T1  - Computational methods for aero-structural analysis and optimisation of aircrafts based on reduced-order structural models
T2  - MEGADESIGN and MegaOpt - German initiatives for aerodynamic simulation and optimization in aircraft design. Results of the closing symposium of the MEGADESIGN and MegaOpt projects, Braunschweig, Germany, 23 - 24 May, 2007 / Norbert Kroll ... (Eds.) Notes on numerical fluid mechanics and multidisciplinary design. Vol. 107
N2  - In this part of the MEGADESIGN project, aeroelastic effects are introduced into the aerodynamic analysis of aircrafts by coupling DLR’s flow solvers TAU and FLOWer to a Timoshenko-beam solver. The emerging aeroelastic solvers and a method for the automatic identification of Timoshenko-beam models for wing-box structures were integrated into a simulation environment enabling the combined optimisation of aerodynamic wing shape and structure.
Y1  - 2009
SN  - 978-3-642-04092-4
SP  - 135
EP  - 150
PB  - Springer
CY  - Berlin
ER  - 
TY  - CHAP
A1  - Samuelsson, K.
A1  - Scheer, Nico
A1  - Wilson, I.
A1  - Wolf, C.R.
A1  - Henderson, C.J.
ED  - Chackalamannil, Samuel
T1  - Genetically Humanized Animal Models
T2  - Comprehensive Medicinal Chemistry III. 3rd Edition
N2  - Genetically humanized mice for proteins involved in drug metabolism and toxicity and mice engrafted with human hepatocytes are emerging as promising in vivo models for improved prediction of the pharmacokinetic, drug–drug interaction, and safety characteristics of compounds in humans. This is an overview on the genetically humanized and chimeric liver-humanized mouse models, which are illustrated with examples of their utility in drug metabolism and toxicity studies. The models are compared to give guidance for selection of the most appropriate model by highlighting advantages and disadvantages to be carefully considered when used for studies in drug discovery and development.
KW  - Chimeric liver-humanized mice
KW  - Drug distribution
KW  - Drug metabolism
KW  - Toxicology
KW  - Knockout mice
Y1  - 2017
SN  - 978-0-12-803201-5
U6  - https://doi.org/10.1016/B978-0-12-409547-2.12376-5
SP  - 130
EP  - 149
PB  - Elsevier
CY  - Saint Louis
ER  - 
TY  - CHAP
A1  - Savitskaya, Irina S.
A1  - Kistaubayeva, Aida S.
A1  - Akimbekov, Nuraly S.
A1  - Digel, Ilya
A1  - Shokatayeva, Dina
A1  - Zhubanova, Azhar Achmet
T1  - Prospective Use of Probiotics Immobilized on Sorbents with Nanostructured Surfaces
T2  - Carbon Nanomaterials in Biomedicine and the Environment
N2  - Activated carbons are known as excellent adsorbents. Their applications include the adsorptive removal of color, odor, taste, undesirable organic and inorganic pollutants from drinking and waste water; air purification in inhabited spaces; purification of many chemicals, pharmaceutical products and many others. This chapter elucidates the role of normal microflora in the maintenance of human health and presents materials on possible clinical displays of microecological infringements and ways of their correction. It presents new developments concerning new probiotics with immobilized Lactobacillus and Bacillus. The chapter considers the mechanisms of the intestine disbacteriosis correction by sorbed probiotics. It demonstrates the advantages and creation prospects of immobilized probiotics developed on the basis of carbonized rice husk. There are great prospects for the development of medical biotechnology due to use of carbon sorbents with a nanostructured surface. Microbial communities form a biocenosis of the biotope and together with the host organism create permanent or temporary ecosystems.
Y1  - 2020
SN  - 978-981-4800-27-3
U6  - https://doi.org/10.1201/9780429428647-12
SP  - 229
EP  - 267
PB  - Jenny Stanford Publishing
CY  - Singapore
ER  - 
TY  - CHAP
A1  - Scheer, Nico
A1  - Chu, Xiaoyan
A1  - Salphati, Laurent
A1  - Zamek-Gliszczynski, Maciej J.
ED  - Nicholls, Glynis
T1  - Knockout and humanized animal models to study membrane transporters in drug development
T2  - Drug Transporters: Volume 1: Role and Importance in ADME and Drug Development
Y1  - 2016
SN  - 978-1-78262-379-3
U6  - https://doi.org/10.1039/9781782623793-00298
SP  - 298
EP  - 332
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  - 
TY  - CHAP
A1  - Schmitz, Manfred
A1  - Dietze, Christian
A1  - Czarnecki, Christian
ED  - Urbach, Nils
ED  - Röglinger, Maximilian
T1  - Enabling digital transformation through robotic process automation at Deutsche Telekom
T2  - Enabling digital transformation through robotic process automation at Deutsche Telekom
N2  - Due to the high number of customer contacts, fault clearances, installations, and product provisioning per year, the automation level of operational processes has a significant impact on financial results, quality, and customer experience. Therefore, the telecommunications operator Deutsche Telekom (DT) has defined a digital strategy with the objectives of zero complexity and zero complaint, one touch, agility in service, and disruptive thinking. In this context, Robotic Process Automation (RPA) was identified as an enabling technology to formulate and realize DT’s digital strategy through automation of rule-based, routine, and predictable tasks in combination with structured and stable data.
Y1  - 2019
SN  - 978-3-319-95272-7
U6  - https://doi.org/10.1007/978-3-319-95273-4_2
SP  - 15
EP  - 33
PB  - Springer
CY  - Cham
ER  -