TY - JOUR A1 - Manea, Marilena A1 - Leurs, Ulrike A1 - Orban, Erika A1 - Baranyai, Zsuzsa A1 - Öhlschläger, Peter A1 - Marquardt, Andreas A1 - Schulcz, Akos A1 - Tejeda, Miguel T1 - Enhanced Enzymatic Stability and Antitumor Activity of Daunorubicin-GnRH-III Bioconjugates Modified in Position 4 JF - Bioconjugate Chemistry Y1 - 2011 SN - 1520-4812 VL - 22 IS - 7 SP - 1320 EP - 1329 PB - ACS CY - Washington, DC ER - TY - JOUR A1 - Immel, Timo A. A1 - Groth, Ulrich A1 - Huhn, Thomas A1 - Öhlschläger, Peter T1 - Titanium salan complexes displays strong antitumor properties in vitro and in vivo in mice JF - PLoS ONE N2 - The anticancer activity of titanium complexes has been known since the groundbreaking studies of Köpf and Köpf-Maier on titanocen dichloride. Unfortunately, possibly due to their fast hydrolysis, derivatives of titanocen dichloride failed in clinical studies. Recently, the new family of titanium salan complexes containing tetradentate ONNO ligands with anti-cancer properties has been discovered. These salan complexes are much more stabile in aqueous media. In this study we describe the biological activity of two titanium salan complexes in a mouse model of cervical cancer. High efficiency of this promising complex family was demonstrated for the first time in vivo. From these data we conclude that titanium salan complexes display very strong antitumor properties exhibiting only minor side effects. Our results may influence the chemotherapy with metallo therapeutics in the future. Y1 - 2011 U6 - http://dx.doi.org/10.1371/journal.pone.0017869 VL - 6 IS - 3 PB - Plos CY - San Francisco, California, US ER - TY - JOUR A1 - Oosterhuis, Koen A1 - Öhlschläger, Peter A1 - Berg, Joost H. van den A1 - Toebes, Mireille A1 - Gomez, Raquel A1 - Schumacher, Ton N. A1 - Haanen, John B. T1 - Preclinical development of highly effective and safe DNA vaccines directed against HPV 16 E6 and E7 JF - International Journal of Cancer Y1 - 2011 SN - 1097-0215 VL - 129 IS - 2 SP - 397 EP - 406 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Öhlschläger, Peter A1 - Spies, Elmar A1 - Alvarez, Gerardo A1 - Quetting, Michael A1 - Groettrup, Marcus T1 - The combination of TLR-9 adjuvantation and electroporation-mediated delivery enhances in vivo antitumor responses after vaccination with HPV-16 E7 encoding DNA JF - International Journal of Cancer. 128 (2011), H. 2 Y1 - 2011 SN - 1097-0215 SP - 473 EP - 481 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Krott, Daniel A1 - Gerhards, Michael A1 - Skorupa, Sascha A1 - Sander, Volker T1 - NHiLA - Bridging the Gap Between .NET and UNICORE JF - UNICORE Summit 2011 : proceedings, 7-8 July 2011, Torun, Poland / Mathilde Romberg ... (Eds.) Y1 - 2011 SN - 9783893367504 N1 - UNICORE Summit ; (2011 ; 2011.07.07-08 ; Torun) ; Schriften des Forschungszentrums Jülich IAS Series 9 SP - 77 EP - 86 PB - Forschungszentrum Jülich CY - Jülich ER - TY - JOUR A1 - Gerhards, M. A1 - Skorupa, S. A1 - Sander, Volker A1 - Pfeiffer, P. A1 - Belloum, A. T1 - Towards a security framework for a WS-HumanTask processor JF - 7th International Conference on Network and Service Management (CNSM), 2011 Paris Y1 - 2011 SN - 978-3-901882-44-9 SP - 1 EP - 5 PB - IEEE CY - New York ER - TY - JOUR A1 - Bergmann, Sandra A1 - Demuth, Bastian A1 - Sander, Volker T1 - A Web Framework for Workflow Submission and Monitoring via UNICORE 6 based on Distributable Scientific Workflow Templates JF - UNICORE Summit 2011 : proceedings, 7-8 July 2011, Torun, Poland / Mathilde Romberg ... (Eds.) Y1 - 2011 SN - 9783893367504 N1 - UNICORE Summit ; (2011 ; 2011.07.07-08 ; Torun) ; Schriften des Forschungszentrums Jülich IAS Series 9 SP - 45 EP - 50 PB - Forschungszentrum Jülich CY - Jülich ER - TY - JOUR A1 - Funke, Harald A1 - Börner, Sebastian A1 - Falk, F. A1 - Hendrick, P. T1 - Control system modifications and their effects on the operation of a hydrogen-fueled Auxiliary Power Unit JF - XX international symposium on air breathing engines 2011 : ISABE 2011, Gothenburg, Sweden, 12-16 September, 2011. Vol. 2. Y1 - 2011 SN - 9781618391803 N1 - 20th International Symposium on Air Breathing Engines 2011 : (ISABE 2011) : Gothenburg, Sweden, 12-16 September, 2011. SP - 929 EP - 938 PB - American Institute of Aeronautics and Astronautics CY - Reston, VA ER - TY - JOUR A1 - Esch, Thomas A1 - Funke, Harald A1 - Roosen, Peter A1 - Jarolimek, Ulrich T1 - Biogenic Vehicle Fuels in General Aviation Aircrafts JF - MTZ worldwide. 72 (2011), H. 1 Y1 - 2011 N1 - recherchierbar für Angehörige der FH Aachen SP - 38 EP - 43 PB - Springer Automotive Media CY - Wiesbaden ER - TY - JOUR A1 - Funke, Harald A1 - Recker, E. A1 - Bosschaerts, W. A1 - Boonen, Q. A1 - Börner, Sebastian T1 - Parametrical study of the „Micromix“ hydrogen combustion principle JF - 10th International Symposium on Experimental and Computational Aerothermodynamics of Internal Flows, ISAIF10-049, Brussels, Belgium, 4-7 July 2011 Y1 - 2011 ER - TY - JOUR A1 - Funke, Harald A1 - Börner, Sebastian A1 - Krebs, W. A1 - Wolf, E. T1 - Experimental Characterization of Low NOx Micromix Prototype Combustors for Industrial Gas Turbine Applications JF - ASME Turbo Expo 2011 ; Vancouver, Canada, June 6-10, 2011 Y1 - 2011 N1 - GT2011-45305 ER - TY - JOUR A1 - Wagner, Torsten A1 - Miyamoto, Ko-ichiro A1 - Shigihara, Noriko A1 - Schöning, Michael Josef A1 - Yoshinobu, Tatsuo T1 - Microfluidic systems with free definable sensor spots by an integrated light-addressable potentiometric sensor JF - Procedia Engineering. 25 (2011) Y1 - 2011 SN - 1877-7058 N1 - EurosensorsXXV ; Proc. Eurosensors XXV, September 4-7, 2011, Athens, Greece SP - 791 EP - 794 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Bohrn, U. A1 - Stütz, E. A1 - Fuchs, K. A1 - Fleischer, M. A1 - Schöning, Michael Josef A1 - Wagner, P. T1 - Air Quality Monitoring using a Whole-Cell based Sensor System JF - Procedia Engineering. 25 (2011) Y1 - 2011 SN - 1877-7058 N1 - EurosensorsXXV ; Proc. Eurosensors XXV, September 4-7, 2011, Athens, Greece SP - 1421 EP - 1424 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Werner, Frederik A1 - Wagner, Torsten A1 - Miyamoto, Ko-ichiro A1 - Yoshinobu, Tatsuo A1 - Schöning, Michael Josef T1 - High speed and high resolution chemical imaging based on a new type of OLED-LAPS set-up JF - Procedia Engineering. 25 (2011) Y1 - 2011 SN - 1877-7058 N1 - EurosensorsXXV ; Proc. Eurosensors XXV, September 4-7, 2011, Athens, Greece SP - 346 EP - 349 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Huck, Christina A1 - Jolly, Christina A1 - Wagner, Patrick A1 - Poghossian, Arshak A1 - Schöning, Michael Josef T1 - One-chip integrated dual amperometric/field-effect sensor for the detection of dissolved hydrogen JF - Procedia Engineering. 25 (2011) Y1 - 2011 SN - 1877-7058 N1 - EurosensorsXXV ; Proc. Eurosensors XXV, September 4-7, 2011, Athens, Greece SP - 1161 EP - 1164 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Aggarwal, Prerna A1 - Singh, Virendra A1 - Singh, Arjun A1 - Scherer, Ulrich W. A1 - Singh, Tejvir A1 - Singla, Madan L. A1 - Srivastava, Alok T1 - Physico-chemical transformations in swift heavy ion modified poly(ethyleneterephthalate) JF - Radiation Physics and Chemistry Y1 - 2011 SN - 0969-806X N1 - In Press, Accepted Manuscript SP - 1 EP - 28 PB - Pergamon Press CY - Oxford ER - TY - JOUR A1 - Hamm, Laurits A1 - Hartung, Frank T1 - High Quality Visual Communication based on IMS JF - Mobilkommunikation : Technologien und Anwendungen ; Vorträge der 16. ITG-Fachtagung vom 18. bis 19. Mai 2011 in Osnabrück / Veranst.: Informationstechnische Gesellschaft im VDE (ITG) ... Tagungsleitung: Ralf Tönjes. Programmkomitee/Hrsg.: Peter Roer Y1 - 2011 SN - 978-3-8007-3352-1 N1 - ITG-Fachbericht ; 230 ; Fachtagung Mobilkommunikation <16, 2011, Osnabrück> SP - 80 EP - 85 PB - VDE-Verl. CY - Berlin ER - TY - JOUR A1 - Hartung, Frank A1 - Kesici, Sinan A1 - Catrein, Daniel T1 - DRM protected Dynamic Adaptive HTTP Streaming JF - Proceedings of the 2011 ACM Multimedia Systems Conference [Elektronische Ressource] : February 23 - 25, 2011, San Jose, CA, USA / sponsored by: ACM SIGMM Y1 - 2011 SN - 9781450305181 N1 - ACM Multimedia Systems Conference ; (2 : ; 2011.02.23-25 : ; San Jose, Calif.) SP - 277 EP - 282 PB - ACM CY - New York, NY ER - TY - JOUR A1 - Ferrein, Alexander A1 - Marais, Stephen A1 - Potgieter, Anet A1 - Steinbauer, Gerald T1 - RoboCup Junior: A vehicle for S&T education in Africa? Y1 - 2011 SN - 978-1-61284-992-8 N1 - AFRICON, 2011 SP - 1 EP - 6 PB - IEEE CY - New York ER - TY - JOUR A1 - Ferrein, Alexander A1 - Rens, Gavin A1 - Meyer, Thomas A1 - Lakemeyer, Gerhard T1 - A Logic for Specifying Partially Observable Stochastic Domains / Rens, Gavin ; Meyer, Thomas ; Ferrein, Alexander ; Lakemeyer, Gerhard JF - Proceedings of the Ninth International Workshop pn non-Monotonic Reasoning, Action and Change (NRAC`11) Y1 - 2011 N1 - Technical Report RMIT-TR-11-02 SP - 15 EP - 22 ER -