TY - CHAP A1 - Holtschoppen, Britta A1 - Cornelissen, Philipp A1 - Butenweg, Christoph A1 - Meskouris, Konstantin T1 - Vereinfachtes Berechnungsverfahren zur Berücksichtigung der Interaktionsschwingung bei flüssigkeitsgefüllten Tankbauwerken unter seismischer Belastung T2 - Berichte der Fachtagung Baustatik-Baupraxis 11 : am 21. und 22. Februar 2011 an der Universität Innsbruck / Hrsg. Gernot Beer ... Y1 - 2011 SN - 978-3-85125-115-9 SP - 155 EP - 162 PB - Inst. für Baustatik, Techn. Univ. Graz CY - Graz ER - TY - JOUR A1 - Norda, Hannah A1 - Butenweg, Christoph T1 - Möglichkeiten und Grenzen der Anwendbarkeit statisch nichtlinearer Verfahren nach DIN EN 1998-1 JF - Bauingenieur : die richtungsweisende Zeitschrift im Bauingenieurswesen ; offizielle Zeitschrift der VDI-Gesellschaft Bautechnik. Beilage: D-A-CH-Mitteilungsblatt Y1 - 2011 SN - 1436-4867 (E-Journal); 0005-6650 (Print) N1 - Printausgabe in der Bibliothek Bayernallee vorhanden: 13 Z 049-2011 VL - Band 86 SP - S13 EP - S21 PB - VDI Fachmedien CY - Düsseldorf ER - TY - JOUR A1 - Lind, Thorsten Patric T1 - Keine Beseitigung der Zahlungsunfähigkeit und ihrer Kenntnis durch Patronatserklärung : BGH, Urteil vom 19.05.2011 - IX ZR 9/10 : Anmerkung JF - Fachdienst Zivilrecht - LMK - Kommentierte BGH-Rechtsprechung, Lindenmaier-Möhring Y1 - 2011 SN - 1611-1095 IS - Ausg. 8 SP - 320922 PB - Beck CY - München ER - TY - JOUR A1 - Lind, Thorsten Patric T1 - Handelndenhaftung bei Vorrats- oder Mantel-GmbH nur für vor Offenlegung der wirtschaftlichen Neugründung ohne Zustimmung aller Gesellschafter vorgenommene Geschäfte : BGH, Urteil vom 12.07.2011 - II ZR 71/11 : Anmerkung JF - Fachdienst Zivilrecht - LMK - Kommentierte BGH-Rechtsprechung, Lindenmaier-Möhring Y1 - 2011 SN - 1611-1095 IS - 11 PB - Beck CY - München ER - TY - JOUR A1 - Hage, Ralf A1 - Lind, Thorsten Patric T1 - Zur Qualifizierung der von dem Aussonderungsberechtigten aufgewandten Ausbaukosten als Masseverbindlichkeiten JF - Zeitschrift für das gesamte Insolvenzrecht : ZInsO Y1 - 2011 SN - 1615-8032 IS - 50 SP - 2264 EP - 2268 PB - Carl Heymanns Verlag CY - Köln ER - TY - CHAP A1 - Lind, Thorsten Patric T1 - Wirkungen der Eröffnung des Insolvenzverfahrens : §§ 129, 132, 133, 144, 145 T2 - Bankenkommentar zum Insolvenzrecht Y1 - 2011 SN - 978-3-940976-55-0 SP - 1145 EP - 1585 PB - Finanz Colloquium CY - Heidelberg ER - TY - JOUR A1 - Mottaghy, Darius A1 - Pechnig, Renate A1 - Vogt, Christian T1 - The geothermal project Den Haag: 3D numerical models for temperature prediction and reservoir simulation JF - Geothermics N2 - The proposed Den Haag Zuidwest district heating system of the city of The Hague consists of a deep doublet in a Jurassic sandstone layer that is designed for a production temperature of 75 °C and a reinjection temperature of 40 °C at a flow rate of 150 m3 h−1. The prediction of reservoir temperature and production behavior is crucial for success of the proposed geothermal doublet. This work presents the results of a study of the important geothermal and geohydrological issues for the doublet design. In the first phase of the study, the influences of the three-dimensional (3D) structures of anticlines and synclines on the temperature field were examined. A comprehensive petrophysical investigation was performed to build a large scale 3D-model of the reservoir. Several bottomhole temperatures (BHTs), as well as petrophysical logs were used to calibrate the model using thermal conductivity measurements on 50 samples from boreholes in different lithological units in the study area. Profiles and cross sections extracted from the calculated temperature field were used to study the temperature in the surrounding areas of the planned doublet. In the second phase of the project, a detailed 3D numerical reservoir model was set up, with the aim of predicting the evolution of the producer and injector temperatures, and the extent of the cooled area around the injector. The temperature model from the first phase provided the boundary conditions for the reservoir model. Hydraulic parameters for the target horizons, such as porosity and permeability, were taken from data available from the nearby exploration wells. The simulation results are encouraging as no significant thermal breakthrough is predicted. For the originally planned location of the producer, the extracted water temperature is predicted to be around 79 °C, with an almost negligible cooling in the first 50 years of production. When the producer is located shallower parts of the reservoir, the yield water temperatures is lower, starting at ≈76 °C and decreasing to ≈74 °C after 50 years of operation. This comparatively larger decrease in temperature with time is caused by the structural feature of the reservoir, namely a higher dip causes the cooler water to easily move downward. In view of the poor reservoir data, the reservoir simulation model is constructed to allow iterative updates using data assimilation during planned drilling, testing, and production phases. Measurements during an 8 h pumping test carried out in late 2010 suggest that a flow rate of 150 m3 h−1 is achievable. Fluid temperatures of 76.5 °C were measured, which is very close to the predicted value. Y1 - 2011 U6 - http://dx.doi.org/10.1016/j.geothermics.2011.07.001 SN - 0375-6505 VL - 40 IS - 3 SP - 199 EP - 210 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Kirsch, Ansgar A1 - Mattle, Bruno T1 - Einflussfaktoren auf die Erddruckverteilung bei eingeschütteten Tunneln T2 - Baustatik Baupraxis : BB / Fachtagung Baustatik Baupraxis. Lehrstühle und Institute für Statik, TH Aachen, TU Berlin, U Bochum [u.a.] Y1 - 2011 SP - 1 EP - 8 ER - TY - JOUR A1 - Jordan, Sabine D. A1 - Krüger, Markus A1 - Willmes, Diana M. A1 - Redemann, Nora A1 - Wunderlich, F. Thomas A1 - Brönneke, Hella S. A1 - Merkwirth, Carsten A1 - Kashkar, Hamid A1 - Olkkonen, Vesa M. A1 - Böttger, Thomas A1 - Braun, Thomas A1 - Seibler, Jost A1 - Brüning, Jens C. T1 - Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism JF - Nature Cell Biology N2 - The contribution of altered post-transcriptional gene silencing to the development of insulin resistance and type 2 diabetes mellitus so far remains elusive. Here, we demonstrate that expression of microRNA (miR)-143 and 145 is upregulated in the liver of genetic and dietary mouse models of obesity. Induced transgenic overexpression of miR-143, but not miR-145, impairs insulin-stimulated AKT activation and glucose homeostasis. Conversely, mice deficient for the miR-143–145 cluster are protected from the development of obesity-associated insulin resistance. Quantitative-mass-spectrometry-based analysis of hepatic protein expression in miR-143-overexpressing mice revealed miR-143-dependent downregulation of oxysterol-binding-protein-related protein (ORP) 8. Reduced ORP8 expression in cultured liver cells impairs the ability of insulin to induce AKT activation, revealing an ORP8-dependent mechanism of AKT regulation. Our experiments provide direct evidence that dysregulated post-transcriptional gene silencing contributes to the development of obesity-induced insulin resistance, and characterize the miR-143–ORP8 pathway as a potential target for the treatment of obesity-associated diabetes. Y1 - 2011 U6 - http://dx.doi.org/10.1038/ncb2211 SN - 1465-7392 VL - 13 IS - 4 SP - 434 EP - 446 PB - Nature CY - New York ER - TY - JOUR A1 - Hasegawa, Maki A1 - Kapelyukh, Yury A1 - Tahara, Harunobu A1 - Seibler, Jost A1 - Rode, Anja A1 - Krueger, Sylvia A1 - Lee, Dongtao N. A1 - Wolf, C. Roland A1 - Scheer, Nico T1 - Quantitative prediction of human pregnane X receptor and cytochrome P450 3A4 mediated drug-drug interaction in a novel multiple humanized mouse line JF - Molecular Pharmacology Y1 - 2011 U6 - http://dx.doi.org/10.1124/mol.111.071845 SN - 1521-0111 VL - 80 IS - 33 SP - 518 EP - 528 PB - ASPET CY - Bethesda, Md. ER - TY - JOUR A1 - Raab, Monika A1 - Kappel, Sven A1 - Krämer, Andrea A1 - Sanhaji, Mourad A1 - Matthess, Yves A1 - Kurunci-Csacsko, Elisabeth A1 - Calzada-Wack, Julia A1 - Rathkolb, Birgit A1 - Rosman, Jan A1 - Adler, Thure A1 - Busch, Dirk H. A1 - Esposito, Irene A1 - Fuchs, Helmut A1 - Gailus-Durner, Valérie A1 - Klingenspor, Martin A1 - Wolf, Eckhard A1 - Sänger, Nicole A1 - Prinz, Florian A1 - Hrabe de Angelis, Martin A1 - Seibler, Jost A1 - Yuan, Juping A1 - Bergmann, Martin A1 - Knecht, Rainald A1 - Kreft, Bertolt A1 - Strebhardt, Klaus T1 - Toxicity modelling of Plk1-targeted therapies in genetically engineered mice and cultured primary mammalian cells JF - Nature Communications Y1 - 2011 U6 - http://dx.doi.org/10.1038/ncomms1395 SN - 2041-1723 VL - 2 IS - 395 SP - 1 EP - 11 PB - Nature CY - London ER - TY - JOUR A1 - Inagaki, Akiko A1 - Sleddens-Linkels, Esther A1 - Wassenaar, Evelyne A1 - Ooms, Marja A1 - Cappellen, Wiggert A. van A1 - Hoeijmakers, Jan H. J. A1 - Seibler, Jost A1 - Vogt, Thomas F. A1 - Shin, Myung K. A1 - Grootegoed, J. Anton A1 - Baarends, Willy M. T1 - Meiotic functions of RAD18 JF - Journal of Cell Science Y1 - 2011 U6 - http://dx.doi.org/10.1242/jcs.081968 SN - 1477-9137 VL - 124 IS - 16 SP - 2837 EP - 2850 PB - Company of Biologists Limited CY - Cambridge ER - TY - CHAP A1 - Fissabre, Anke A1 - Niethammer, Bernd ED - Graf, Franz T1 - Early Glazed Curtain Walls and their Preservation T2 - Il vetro nell’architettura del XX secolo : conservazione e restauro = Glass in the 20th Century Architecture : Preservation and Restoration Y1 - 2011 SN - 9788887624502 SP - 185 EP - 199 PB - Mendrisio Academy Press CY - Mendrisio ER - TY - JOUR A1 - Fissabre, Anke T1 - Dachterrassen der Renaissance – „Cosa più maravigliosa che gl’orti pensili di Babbilonia“ JF - Architectura : Zeitschrift für Geschichte der Baukunst Y1 - 2011 SN - 0044-863X VL - 41 IS - 1 SP - 27 EP - 46 PB - De Gruyter CY - Berlin ER - TY - CHAP A1 - Stieglitz, Kristian A1 - Wollert, Jörg T1 - Approach of using ultra-wideband-radio in industrial real-time ethernet networks T2 - The 4th International Multi-Conference on Engineering and Technological Innovation : IMETI : July 19th - July 22nd, 2011, Orlando, Florida, USA Y1 - 2011 SP - 1 EP - 6 ER - TY - CHAP A1 - Buda, Aurel A1 - Wollert, Jörg T1 - Leistungsbewertung von Ultra Wideband Funktechnologien nach ECMA 368 für den Einsatz in industriellen Kommunikationssystemen T2 - Kommunikation in der Automation : Magdeburg, 27. - 28.09.2011 ; 2. Jahreskolloquium Kommunikation in der Automation ; KOMMA 2011 / Ulrich Jumar ... (Hrsg.) Y1 - 2011 SN - 978-3-940961-58-7 PB - ifak, Institut für Automation und Kommunikation e.V. Magdeburg an der Otto-von-Guericke-Universität Magdeburg CY - Magdeburg ER - TY - JOUR A1 - Siers, Carsten A1 - Sögtrop, Christian A1 - Borrmann, Arne A1 - Hoepner, Gert T1 - Vernetzung von Kultur und Struktur JF - Sales-Business : der Navigator für Vertrieb, Verkauf und Strategie Y1 - 2011 U6 - http://dx.doi.org/10.1365/s35141-011-0093-5 SN - 1616-7902 VL - 20 IS - 5 SP - 32 EP - 34 PB - Springer Gabler CY - Wiesbaden ER - TY - JOUR A1 - Fuchs, Britta A1 - Ritz, Thomas T1 - Absatzkanäle kaum verknüpft JF - IT-Mittelstand : IT-Business im Mittelstand Y1 - 2011 VL - 2011 IS - 9 SP - 16 PB - Medienhaus-Verlag CY - Bergisch-Gladbach ER - TY - CHAP A1 - Höttges, Jörg ED - Pinnekamp, Johannes T1 - GIS-gestützte Niederschlagswasserbeseitigungskonzepte - Aufgaben und Inhalte T2 - 44. Essener Tagung für Wasser- und Abfallwirtschaft : "zukunftsfähige Wasserwirtschaft - kosteneffizient und energiebewusst"; 23. bis 25. März 2011 im Eurogress Aachen Y1 - 2011 SN - 978-3-938996-29-4 N1 - Gewässerschutz, Wasser, Abwasser ; 223 SP - 29/1 EP - 29/14 PB - Ges. zur Förderung der Siedlungswasserwirtschaft an der RWTH Aachen CY - Aachen ER - TY - CHAP A1 - Höttges, Jörg A1 - Rolfing, Richard A1 - Sieker, Heiko A1 - Siekmann, Marko A1 - Wermter, Paul ED - Pinnekamp, Johannes T1 - GIS-gestützte Erstellung von Niederschlagswasserbeseitigungskonzepten T2 - 12. Kölner Kanal- und Kläranlagen-Kolloquium : 13. und 14. Oktober 2011 im Maternushaus, Köln / ISA, Institut und Lehrstuhl für Siedlungswasserwirtschaft Y1 - 2011 SN - 978-3-938996-08-9 N1 - Aachener Schriften zur Stadtentwässerung ; 15 SP - 8/1 EP - 8/13 PB - Ges. zur Förderung der Siedlungswasserwirtschaft an der RWTH Aachen CY - Aachen ER -