TY  - JOUR
A1  - Murgan, Ilina
A1  - Beyer, Sonja
A1  - Kotliar, Konstantin
A1  - Weber, Lutz
A1  - Bechtold-Dalla Pozza, Susanne
A1  - Dalla Pozza, Robert
A1  - Wegner, Aharon
A1  - Sitnikova, Diana
A1  - Stock, Konrad
A1  - Heemann, Uwe
A1  - Schmaderer, Christoph
A1  - Baumann, M.
T1  - Arterial and Retinal Vascular Changes in Hypertensive and Prehypertensive Adolescents
JF  - American Journal of Hypertension
Y1  - 2013
SN  - 1941-7225
VL  - 26
IS  - 3
SP  - 400
EP  - 408
PB  - Oxford University Press
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Hanssen, Henner
A1  - Eberhardt, Karla
A1  - Vilser, Walthard
A1  - Schmaderer, Christoph
A1  - Halle, Martin
A1  - Heemann, Uwe
A1  - Baumann, M.
T1  - Retinal pulse wave velocity in young male normotensive and mildly hypertensive subjects
JF  - Microcirculation
Y1  - 2013
SN  - 1549-8719
N1  - Accepted Article (Accepted, unedited articles published online and citable. The final edited and typeset version of record will appear in future.)
PB  - Wiley
CY  - Malden
ER  - 
TY  - THES
A1  - Kotliar, Konstantin
T1  - Razrabotka i analiz matematicheskih modelei nezavisimogo i svyazannogo funkcionirovaniya drenazhnoi i akkomodacionnoi regulyatornyh sistem chelovecheskogo glaza
T2  - Mathematische Modelle der interaktiven und unabhängigen Funktion von Drainage- und Akkommodations-Regelungssystemen des menschlichen Auges
Y1  - 1998
N1  - St.-Petersburg, Russland, Univ., Diss., 1998 
[Lehrstuhl für Theoretische Mechanik der
Staatlichen Polytechnischen Universität St.-Petersburg] 
Originaltitel: Razrabotka i analiz
matematicheskih modelei nezavisimogo i svyazannogo funkcionirovaniya
drenazhnoi i akkomodacionnoi regulyatornyh sistem chelovecheskogo
glaza. 328 S.
PB  - -
ER  - 
TY  - THES
A1  - Kotliar, Konstantin
T1  - Functional in-vivo assessment and biofluidmechanical analysis of age-related and pathological microstructural changes in retinal vessels [Elektronische Ressource]
Y1  - 2008
N1  - München, Techn. Univ., Diss., 2008
PB  - -
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Svetlova, O. V.
A1  - Stegaev, V. A.
A1  - Parkhomov, S. D.
T1  - Biomechanical substantiation of relatively low efficiency of recurrent laser trabeculoplasty / Svetlova, O. V. ; Stagaev, V. A. ; Parkhomov, S. D. ; Kotliar, K. E. ; Makarov, F. N. ;  Smolnikov, B. A. ; Koshitz, I. N.
JF  - Glaukoma (2004)
Y1  - 2004
N1  - Original in Russisch
SP  - 29
EP  - 39
PB  - -
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Svetlova, O. V.
A1  - Sourjikov, A. V.
A1  - Zaseeva, M. V.
T1  - Biomechanical peculiarities of aqueous humor production system and outflow regulation system / Svetlova, O. V. ; Sourjikov, A. V. ; Kotliar, K. E. ; Zaseeva, M. V. ; Shukhaev, S. V. ; Koshitz, I. N.
JF  - Glaukoma (2004)
Y1  - 2004
N1  - Original in Russisch
SP  - 66
EP  - 76
PB  - -
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Koshitz, I. N.
A1  - Svetlowa, O. V.
A1  - Makarov, F. N.
T1  - Biomechanical analysis of traditional and contemporary conceptions on pathogenesis of the primary open angle glaucoma / Koshitz, I. N. ; Svetlova, O. V. ; Kotliar, K. E. ; Makarov, F. N. ;  Smolnikov, B. A.
JF  - Glaukoma (2005)
Y1  - 2005
N1  - Original in Russisch
SP  - 41
EP  - 63
PB  - -
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Koshitz, I. N.
A1  - Svetlova, O. V.
A1  - Zaseeva, M. V.
T1  - Physiological principles of hypotensive therapy of open-angle glaucoma during presbyopic period. Part I Initial theoretical presuppositions, hypotheses and facts / Koshitz, I. N. ; Svetlova, O. V. ; Zaseeva, M. V. ; Shuhaev, S. V. ; Makarov, F. N. ; Kotli
JF  - Glaukoma (2006)
Y1  - 2006
N1  - Original in Russisch
SP  - 35
EP  - 53
PB  - -
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Koshitz, I. N.
A1  - Svetlowa, O. V.
A1  - Zaseeva, M. V.
T1  - Physiological principles of hypotensive therapy of open-angle glaucoma during presbyopic period. Part II Promising algorithms of practical sparing applications / Koshitz, I. N. ; Svetlova, O. V. ; Zaseeva, M. V. ; Shuhaev, S. V. ; Makarov, F. N. ; Kotliar
JF  - Glaukoma (2006)
Y1  - 2006
N1  - Original in Russisch
SP  - 51
EP  - 70
PB  - -
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Svetlova, O. V.
A1  - Zinoviewa, N. V.
A1  - Krylova, I. S.
T1  - Elaboration of the conception of the biomechanical model of the aqueous intraocular outflow / Svetlova, O. V. ; Zinoviewa, N. V. ; Krylova, I. S. ; Koshitz, I. N. ; Smolnikov, B. A. ; Fedorova, E. M. ; Kotliar, K. E.
JF  - Rossiiskii zhurnal biomekhaniki = Russian Journal of biomechanics. 5 (2001), H. 3
Y1  - 2001
SN  - 1812-5123
SP  - 23
EP  - 27
PB  - -
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Lanzl, Ines M.
A1  - Witta, Birka
A1  - Vilser, Walthard
T1  - Reaktion retinaler Gefäßdurchmesser auf 100 % O2-Atmung - funktionelle Messung mit dem Retinal Vessel Analyzer an 10 Probanden / Lanzl, Ines M. ; Witta, Birke ; Kotliar, Konstantin ; Vilser, Walthard
JF  - Klinische Monatsblätter für Augenheilkunde. 217 (2000), H. 4
Y1  - 2000
SN  - 1439-3999
N1  - = Retinal vessel reaction to 100 % O2 breathing - functional imaging by retinal vessel analyzer in 10 volunteers
SP  - 231
EP  - 235
PB  - -
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Lanzl, Ines M.
A1  - Maier, Mathias
A1  - Feucht, Nikolaus
T1  - Intraocular pressure effects of pegaptanib (macugen) injections in patients with and without glaucoma / Lanzl, Ines M. ; Maier, Mathias ; Feucht, Nikolaus ; Lohmann, Chris P. ; Kotliar, Konstantin E.
JF  - American Journal of Ophthalmology . 145 (2008), H. 1
Y1  - 2008
SN  - 1879-1891
SP  - 185
EP  - 185
PB  - -
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Vilser, Walthatd
A1  - Nagel, Edgar
A1  - Lanzl, Ines M.
T1  - Retinal vessel reaction in response to chromatic flickering light / Kotliar, Konstantin E. ; Vilser, Walthard ; Nagel, Edgar ; Lanzl, Ines M.
JF  - Graefe's Archive for Clinical and Experimental Ophthalmology. 242 (2004), H. 5
Y1  - 2004
SN  - 1435-702X
SP  - 377
EP  - 392
PB  - -
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Bauer, S. M.
A1  - Zamuraev, L. A.
T1  - Model of the transversely isotropic spherical layer for estimation of intraocular pressure changes after intravitreal injections / Bauer, S. M. ; Zamuraev, L. A. ; Kotliar, K. E.
JF  - Rossiiskii zhurnal biomekhaniki = Russian Journal of biomechanics. 10 (2006), H. 2
Y1  - 2006
SN  - 1812-5123
SP  - 41
EP  - 47
PB  - -
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Kozlova, Tatiana V.
A1  - Lanzl, Ines M.
T1  - Postoperative aqueous outflow in the human eye after glaucoma filtration surgery: biofluidmechanical considerations
JF  - Biomedizinische Technik = Biomedical Engineering
Y1  - 2009
SN  - 1862-278X
VL  - 54
IS  - 1
SP  - 14
EP  - 22
PB  - -
ER  - 
TY  - JOUR
A1  - Seidova, Seid-Fatima
A1  - Kotliar, Konstantin
A1  - Foerger, Frauke
A1  - Klopfer, Matthias
A1  - Lanzl, Ines
T1  - Functional retinal changes in Gaucher disease
JF  - Documenta Ophthalmologica
Y1  - 2009
SN  - 1573-2622
VL  - 118
IS  - 2
SP  - 151
EP  - 154
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Garhofer, Gerhard
A1  - Bek, Toke
A1  - Boehm, Andreas G.
A1  - Gherghel, Doina
A1  - Grundwald, Juan
A1  - Jeppesen, Peter
A1  - Kergoat, Hélène
A1  - Kotliar, Konstantin
A1  - Lanzl, Ines
A1  - Lovasik, John V.
A1  - Nagel, Edgar
A1  - Vilser, Walthard
A1  - Orgul, Selim
A1  - Schmetterer, Leopold
T1  - Use of the retinal vessel analyzer in ocular blood flow research
JF  - Acta Ophthalmol
N2  - The present article describes a standard instrument for the continuous online determination of retinal vessel diameters, the commercially available retinal vessel analyzer. This report is intended to provide informed guidelines for measuring ocular blood flow with this system. The report describes the principles underlying the method and the instruments currently available, and discusses clinical protocol and the specific parameters measured by the system. Unresolved questions and the possible limitations of the technique are also discussed.
Y1  - 2010
U6  - http://dx.doi.org/10.1111/j.1755-3768.2009.01587.x
SN  - 1755-3768
VL  - 88
IS  - 7
SP  - 717
EP  - 722
PB  - Wiley-Blackwell
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Baumann, Marcus
A1  - Schwarz, Sonja
A1  - Kotliar, Konstantin
A1  - Eynatten, Maximilian von
A1  - Trucksaess, Arno
A1  - Burckhardt, Klaus
A1  - Lutz, Jens
A1  - Heemann, Uwe
A1  - Lanzl, Ines
T1  - Non-diabetic chronic kidney disease influences retinal microvasculature
JF  - Kidney and Blood Pressure Research
Y1  - 2009
SN  - 1423-0143
VL  - 32
IS  - 6
SP  - 428
EP  - 433
PB  - -
ER  - 
TY  - JOUR
A1  - Burkhardt, Klaus
A1  - Schwarz, Sonja
A1  - Pan, Chengrui
A1  - Stelter, Felix
A1  - Kotliar, Konstantin
A1  - Eynatten, Maxilian von
A1  - Sollinger, Daniel
A1  - Lanzl, Ines
A1  - Heemann, Uwe
A1  - Baumann, Marcus
T1  - Myeloid-related protein 8/14 complex describes microcirculatory alterations in patients with type 2 diabetes and nephropathy
JF  - Cardiovascular Diabetology
Y1  - 2009
SN  - 1475-2840
VL  - 8
IS  - 10
SP  - 1
EP  - 8
PB  - -
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Baumann, Marcus
A1  - Vilser, Walthard
A1  - Lanzl, Ines M.
T1  - Pulse wave velocity in retinal arteries of healthy volunteers
JF  - British Journal of Ophthalmology (eBJO)
Y1  - 2011
SN  - 1468-2079
VL  - 95
IS  - 11
SP  - 675
EP  - 679
PB  - BMJ Publ. Group
CY  - London
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Lanzl, Ines M.
A1  - Schmidt-Trucksäss, A.
A1  - Sitnikova, Diana
A1  - Ali, Mohammad
A1  - Blume, Katharina
A1  - Halle, Martin
A1  - Hansser, Henner
T1  - Dynamic retinal vessel response to flicker in obesity: A methodological approach
JF  - Microvascular Research
Y1  - 2011
SN  - 0026-2862
VL  - 81
IS  - 1
SP  - 123
EP  - 128
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Dashevsky, Alexey V.
A1  - Lanzl, Ines M.
A1  - Kotliar, Konstantin
T1  - Non-penetrating intracanalicular partial trabeculectomy via the ostia of Schlemm's canal
JF  - Graefe's Archive for Clinical and Experimental Ophthalmology
Y1  - 2011
SN  - 0721-832x
VL  - 249
IS  - 4
SP  - 565
EP  - 573
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Maier, M. M.
A1  - Feucht, N.
A1  - Winkler von Mohrenfels, C.
A1  - Kotliar, Konstantin
A1  - Fabian, E.
A1  - Lohmann, C. P.
T1  - Nahtlose Cerclage mit Skleratunnelfixation. Sutureless Encircling Band - Clinical Experience
JF  - Klinische Monatsblätter für Augenheilkunde
Y1  - 2011
SN  - 0344-6360
VL  - 228
IS  - 5
SP  - 473
EP  - 476
PB  - Thieme
CY  - Stuttgart
ER  - 
TY  - JOUR
A1  - Mikielewicz, Marek
A1  - Kotliar, Konstantin
A1  - Barraquer, Rafael I.
A1  - Michael, Ralph
T1  - Air-pulse corneal applanation signal curve parameters for the characterisation of keratoconus
JF  - British Journal of Ophthalmology (eBJO)
Y1  - 2011
SN  - 1468-2079
VL  - 95
IS  - 6
SP  - 793
EP  - 798
PB  - BMJ Publ. Group
CY  - London
ER  - 
TY  - JOUR
A1  - Pressler, Axel
A1  - Esefeld, Katrin
A1  - Scherr, Johannes
A1  - Ali, Mohammad
A1  - Hanssen, Henner
A1  - Kotliar, Konstantin
A1  - Lanzl, Ines
A1  - Halle, Martin
A1  - Kaemmerer, Harald
A1  - Schmidt-Trucksäss, Arno
A1  - Hager, Alfred
T1  - Structural alterations of retinal arterioles in adults late after repair of aortic isthmic coarctation
JF  - The American Journal of Cardiology
N2  - Patients after coarctation repair still have an increased risk of cardiovascular or cerebrovascular events. This has been explained by the persisting hypertension and alterations in the peripheral vessels. However, involvement of the central vessels such as the retinal arteries is virtually unknown. A total of 34 patients after coarctation repair (22 men and 12 women; 23 to 58 years old, age range 0 to 32 years at surgical repair) and 34 nonhypertensive controls underwent structural and functional retinal vessel analysis. Using structural analysis, the vessel diameters were measured. Using functional analysis, the endothelium-dependent vessel dilation in response to flicker light stimulation was assessed. In the patients after coarctation repair, the retinal arteriolar diameter was significantly reduced compared to that of the controls (median 182 μm, first to third quartile 171 to 197; vs 197 μm, first to third quartile 193 to 206; p <0.001). These findings were independent of the peripheral blood pressure and age at intervention. No differences were found for venules. The functional analysis findings were not different between the patients and controls (maximum dilation 3.5%, first to third quartile 2.1% to 4.5% vs 3.6%, first to third quartile 2.2% to 4.3%; p = 0.81), indicating preserved autoregulative mechanisms. In conclusion, the retinal artery diameter is reduced in patients after coarctation repair, independent of their current blood pressure level and age at intervention. As a structural marker of chronic vessel damage associated with past, current, or future hypertension, retinal arteriolar narrowing has been linked to stroke incidence. These results indicate an involvement of cerebral microcirculation in aortic coarctation, despite timely repair, and might contribute to explain the increased rate of cerebrovascular events in such patients.
Y1  - 2010
U6  - http://dx.doi.org/10.1016/j.amjcard.2009.10.070
SN  - 0002-9149
VL  - 105
IS  - 5
SP  - 740
EP  - 744
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Svetlova, O. V.
A1  - Makarov, F. N.
A1  - Zaseeva, M. V.
T1  - Morfologicheskie i funktsional'nye osobennosti resnichnogo poiaska khrustalika kak kliuchevogo ispolnitel'nogo zvena v mekhanizme akkommodatsii glaza cheloveka = Morpho-functional characteristics of lens ciliary body as a key mechanism of accommodation in
JF  - Morfologiia (Saint Petersburg, Russia). 123 (2003), H. 3
Y1  - 2003
SN  - 1026-3543
N1  - Original in Russisch, English abstract
SP  - 7
EP  - 16
PB  - -
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Volkov, V. V.
A1  - Koshits, I. N.
A1  - Svetlova, O. V.
T1  - Biomekhanicheskie osobennosti vzaimodeĭstviia drenazhno i akkomodatsionnoĭ reguliatornykh sistem glaza v norme i pri kontuzionnom podvyvikhe khrustalika / Volkov, V. V. ; Kotliar, K. E. ; Koshits, I. n. ; Svetlova, O. V. ; Smol´nikov, B. A.
JF  - Vestnik oftalmologii. 113 (1997), H. 3
Y1  - 1997
SN  - 0042-465X
N1  - Titelübersetzung: Biomechanical characteristics of interactions between the drainage and accommodation regulatory systems of the eye in health and in contusion lens subluxation ; Original in Russisch, English abstract
SP  - 5
EP  - 7
PB  - -
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Mogilevskiĭ, A. Ia.
A1  - Shilo, A. V.
A1  - Panchekha, A. P.
T1  - [Chaotic non-linear dynamics of alpha-band of the EEg and organization of the cortical activity of P300 wave] / Mogilevskiĭ, A. Ia. ; Kotliar, K. E. ; Shilo, A. V. ; Panchekha, A. P.
JF  - Zhurnal vyssheĭ nervnoĭ deiatelnosti imeni I P Pavlova. 58 (2008), H. 5
Y1  - 2008
SN  - 0044-4677
N1  - Original in Russisch ; English abstract
SP  - 562
EP  - 575
PB  - -
ER  - 
TY  - JOUR
A1  - Menzel, C.
A1  - Kotliar, Konstantin
A1  - Lanzl, I.
T1  - Retrospektive Untersuchung jahreszeitlich bedingter Einflussfaktoren auf den Augeninnendruck therapierter Glaukompatienten
JF  - Der Ophthalmologe
Y1  - 2009
SN  - 1433-0423
VL  - 106
IS  - 11
SP  - 1006
EP  - 1011
PB  - -
ER  - 
TY  - JOUR
A1  - Wiescher, A.
A1  - Kotliar, Konstantin
A1  - Neuhann, T.
A1  - Lanzl, Ines M.
T1  - Rasch progrediente Visusminderung beider Augen bei einem jungen Patienten
JF  - Der Ophthalmologe
N2  - Ein 34-jähriger männlicher Patient stellte sich zur Abklärung einer seit dem 9. Lebensjahr bestehenden und im letzten Jahr rasch progredienten Visusminderung beider Augen bei uns vor. Er beschrieb eine subjektiv zunehmende, im Spiegel für ihn selbst sichtbare, weißliche Trübung in der Pupille beidseits und eine starke Blendempfindlichkeit. Nebenbefundlich gab er rezidivierende Konjunktivitiden und morgens verklebte Lider an. Eine Allergie auf Gräserpollen und eine Unverträglichkeit auf Alkohol sowie mehrere Lebensmittel seien ebenfalls bekannt.

Zusätzlich leidet der Patient an stark ausgeprägtem atopischem Ekzem. Dieses wurde nie systemisch, sondern nur bei Bedarf mit kortisonhaltiger Salbe therapiert.
Y1  - 2010
U6  - http://dx.doi.org/10.1007/s00347-007-1586-x
SN  - 1433-0423
VL  - 105
IS  - 4
SP  - 389
EP  - 392
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Maier, Mathias
A1  - Bauer, Svetlana
A1  - Feucht, Nikolaus
T1  - Effect of intravitreal injections and volume changes on intraocular pressure: clinical results and biomechanical model / Kotliar, Konstantin ; Maier, Mathias ; Bauer, Svetlana ; Feucht, Nikolaus ; Lohmann, Chris ; Lanzl, Ines
JF  - Acta Ophthalmologica Scandinavica. 85 (2007), H. 7
Y1  - 2007
SN  - 1755-3768
SP  - 777
EP  - 781
PB  - -
ER  - 
TY  - JOUR
A1  - Nurispahic, A.
A1  - Kotliar, Konstantin
A1  - Lanzl, I.
T1  - Messung der Akkommodation mittels optischer Biometrie
JF  - Der Ophthalmologe
Y1  - 2008
SN  - 1433-0423
VL  - 105
IS  - 4
SP  - 369
EP  - 375
PB  - -
ER  - 
TY  - JOUR
A1  - Lanzl, Ines M.
A1  - Seidova, Seid-Fatima
A1  - Erben, A.
A1  - Thürmel, K.
A1  - Kotliar, Konstantin
T1  - Diffuse stromale Hornhauttrübungen und Veränderungen der Hände
JF  - Der Ophthalmologe
N2  - Bilaterale stromale Hornhauttrübungen sind für den Augenarzt eine differenzialdiagnostische Herausforderung. Im folgenden Beitrag werden 2 Patieninnen (30 und 36 Jahre) mit unterschiedlich stark ausgeprägter stromaler diffuser Hornhauttrübung vorgestellt. Patientin 1 war kleinwüchsig (114 cm) und Patientin 2 normal groß (172 cm). Beide Patientinnen wiesen veränderte Gelenkstrukturen an Hand und Fußgelenken sowie diffuse stromale Hornhauttrübungen auf. Des Weiteren lagen eine Mitral- und Aorteninsuffizienz (Patientin 1) bzw. eine Aorteninsuffizienz (Patientin 2) vor. Die stromalen diffusen Hornhauttrübungen ließen im Zusammenhang mit den Gelenkveränderungen ein Scheie-Syndrom vermuten. Therapeutisch ist bei Patienten mit Visusminderung eine (lamelläre) Keratoplastik sinnvoll.
Y1  - 2010
U6  - http://dx.doi.org/10.1007/s00347-009-2066-2
SN  - 1433-0423
VL  - 107
IS  - 4
SP  - 363
EP  - 365
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Lanzl, Ines M.
A1  - Seidova, Seid-Fatima
A1  - Maier, Mathias
A1  - Schmidt-Trucksäss, Arno
A1  - Halle, Martin
A1  - Kotliar, Konstantin
T1  - Dynamic retinal vessel response to flicker in age-related macular degeneration patients before and after vascular endothelial growth factor inhibitor injection
JF  - Acta Ophthalmologica
Y1  - 2011
SN  - 1755-3768
VL  - 89
IS  - 5
SP  - 472
EP  - 479
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Maier, Mathias
A1  - Bauer, Svetlana
A1  - Feucht, Nikolaus
A1  - Lohmann, Chris
A1  - Lanzl, Ines
T1  - Intravitreal injection of triamcinolone acetonide and intraocular pressure: author's reply
JF  - Acta Ophthalmologica
Y1  - 2008
SN  - 1755-3768
VL  - 86
IS  - 6
SP  - 692
EP  - 693
PB  - -
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Nagel, Edgar
A1  - Vilser, Walthard
A1  - Lanzl, Ines M.
T1  - Functional in vivo assessment of retinal artery microirregularities in glaucoma / Kotliar, Konstantin E. ; Nagel, Edgar ; Vilser, Walthard ; Lanzl, Ines M.
JF  - Acta Ophthalmologica. 86 (2008), H. 4
Y1  - 2008
SN  - 1755-3768
SP  - 424
EP  - 433
PB  - -
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Lanzl, Ines M.
A1  - Hanssen, Henner
A1  - Eberhardt, Karla
A1  - Vilser, Walthard
A1  - Halle, Martin
A1  - Heemann, Uwe
A1  - Schmidt-Trucksäss, Arno
A1  - Baumann, Marcus
T1  - Does increased blood pressure rather than aging influence retinal pulse wave velocity?
JF  - Investigative Ophthalmology & Visual Science, IOVS
N2  - Purpose: It was demonstrated previously that retinal pulse wave velocity (rPWV) as a measure of retinal arterial stiffness is increased in aged anamnestically healthy volunteers compared with young healthy subjects. Using novel methodology of rPWV assessment this finding was confirmed and investigated whether it might relate to the increased blood pressure usually accompanying the aging process, rather than to the aging itself.

Methods: A total of 12 young 25.5-year-old (24.0–28.8) [median(1st quartile–3rd quartile)] and 12 senior 68.5-year-old (63.8–71.8) anamnestically healthy volunteers; and 12 senior 63.0-year-old (60.8–65.0) validated healthy volunteers and 12 young 33.0-year-old (29.5–35.0) hypertensive patients were examined. Time-dependent alterations of vessel diameter were assessed by the Dynamic Vessel Analyzer in a retinal artery of each subject. The data were filtered and processed using mathematical signal analysis and rPWVs were calculated.

Results: rPWV amounted to 1200 (990-1470) RU (relative units)/s in the hypertensive group and to 1040 (700-2230) RU/s in anamnestically healthy seniors. These differed significantly from rPWVs in young healthy group (410 [280–500] RU/s) and in validated healthy seniors (400 [320–510] RU/s). rPWV associated with age and mean arterial pressure (MAP) in the pooled cohort excluded validated healthy seniors. In a regression model these associations remain when alternately adjusted for MAP and age. When including validated healthy seniors in the pooled cohort only association with MAP remains.

Conclusions: Both aging (with not excluded cardiovascular risk factors) and mild hypertension are associated with elevated rPWV. rPWV increases to a similar extent both in young mildly hypertensive subjects and in aged anamnestically healthy persons. Healthy aging is not associated with increased rPWV.
Y1  - 2012
U6  - http://dx.doi.org/10.1167/iovs.11-8815
SN  - 0146-0404
VL  - 53
IS  - 4
SP  - 2119
EP  - 2126
PB  - ARVO
CY  - Rockville, Md.
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Vilser, W.
A1  - Schmidt-Trucksäss, A.
A1  - Halle, M.
A1  - Lanzl, I. M.
T1  - Zeitliche Schwingungen retinaler Gefäßdurchmesser bei Gesunden unterschiedlichen Alters : Kreuz- und Autokorrelation für dynamische Gefäßanalyse
JF  - Der Ophthalmologe
Y1  - 2009
SN  - 1433-0423
VL  - 106
IS  - 7
SP  - 609
EP  - 618
PB  - -
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Nagel, Edgar
A1  - Vilser, Walthard
A1  - Seidova, Seid-Fatima
A1  - Lanzl, Ines
T1  - Microstructural alterations of retinal arterial blood column along the vessel axis in systemic hypertension
JF  - Investigative Ophthalmology & Visual Science, IOVS
N2  - Purpose: Image analysis by the retinal vessel analyzer (RVA) observes retinal vessels in their dynamic state online noninvasively along a chosen vessel segment. It has been found that high-frequency diameter changes in the retinal artery blood column along the vessel increase significantly in anamnestically healthy volunteers with increasing age and in patients with glaucoma during vascular dilation. This study was undertaken to investigate whether longitudinal sections of the retinal artery blood column are altered in systemic hypertension.

Methods: Retinal arteries of 15 untreated patients with essential arterial hypertension (age, 50.9 ± 11.9 years) and of 15 age-matched anamnestically healthy volunteers were examined by RVA. After baseline assessment, a monochromatic luminance flicker (530–600 nm; 12.5 Hz; 20 s) was applied to evoke retinal vasodilation. Differences in amplitude and frequency of spatial artery blood column diameter change along segments (longitudinal arterial profiles) of 1 mm in length were measured and analyzed using Fourier transformation.

Results: In the control group, average reduced power spectra (ARPS) of longitudinal arterial profiles did not differ when arteries changed from constriction to dilation. In the systemic hypertension group, ARPS during constriction, baseline, and restoration were identical and differed from ARPS during dilation (P < 0.05). Longitudinal arterial profiles in both groups showed significant dissimilitude at baseline and restoration (P < 0.05).

Conclusions: The retinal artery blood column demonstrates microstructural alterations in systemic hypertension and is less irregular along the vessel axis during vessel dilation. These microstructural changes may be an indication of alterations in vessel wall rigidity, vascular endothelial function, and smooth muscle cells in this disease, leading to impaired perfusion and regulation.
Y1  - 2010
U6  - http://dx.doi.org/10.1167/iovs.09-3649
SN  - 0146-0404
VL  - 51
IS  - 4
SP  - 2165
EP  - 2172
PB  - ARVO
CY  - Rockville, Md.
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Lanzl, Ines M.
T1  - Can vascular function be assessed by the interpretation of retinal vascular diameter changes?
JF  - Investigative Ophthalmology & Visual Science, IOVS. 52 (2011), H. 1
Y1  - 2011
SN  - 0146-0404
SP  - 635
EP  - 636
PB  - ARVO
CY  - Rockville, Md.
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Mücke, Bruno
A1  - Vilser, Walthard
A1  - Schilling, Rudolf
T1  - Effect of aging on retinal artery blood column diameter measured along the vessel axis / Kotliar, Konstantin E. ; Mücke, Bruno ; Vilser, Walthard ; Schilling, Rudolf ; Lanzl, Ines M.
JF  - Investigative Ophthalmology & Visual Science, IOVS. 49 (2008), H. 5
Y1  - 2008
SN  - 0146-0404
SP  - 2094
EP  - 2102
PB  - -
ER  - 
TY  - JOUR
A1  - Hanssen, H.
A1  - Nickel, T.
A1  - Drexel, V.
A1  - Hertel, G.
A1  - Emslander, I.
A1  - Sisic, Z.
A1  - Lorang, D.
A1  - Schuster, T.
A1  - Kotliar, Konstantin
A1  - Pressler, A.
A1  - Schmidt-Trucksäss, A.
A1  - Weis, M.
A1  - Halle, M.
T1  - Exercise-induced alterations of retinal vessel diameters and cardiovascular risk reduction in obesity
JF  - Atherosclerosis
Y1  - 2011
SN  - 0021-9150
VL  - 216
IS  - 2
SP  - 433
EP  - 439
PB  - Elsevier
CY  - Amsterdam
ER  -