TY  - JOUR
A1  - Schael, S.
A1  - Atanasyan, A.
A1  - Berdugo, J.
A1  - Bretz, T.
A1  - Czupalla, Markus
A1  - Dachwald, Bernd
A1  - Doetinchem, P. von
A1  - Duranti, M.
A1  - Gast, H.
A1  - Karpinski, W.
A1  - Kirn, T.
A1  - Lübelsmeyer, K.
A1  - Maña, C.
A1  - Marrocchesi, P.S.
A1  - Mertsch, P.
A1  - Moskalenko, I.V.
A1  - Schervan, T.
A1  - Schluse, M.
A1  - Schröder, K.-U.
A1  - Schultz von Dratzig, A.
A1  - Senatore, C.
A1  - Spies, L.
A1  - Wakely, S.P.
A1  - Wlochal, M.
A1  - Uglietti, D.
A1  - Zimmermann, J.
T1  - AMS-100: The next generation magnetic spectrometer in space – An international science platform for physics and astrophysics at Lagrange point 2
JF  - Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
Y1  - 2019
U6  - http://dx.doi.org/10.1016/j.nima.2019.162561
SN  - 0168-9002
VL  - 944
IS  - 162561
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Vu, Duc-Khoi
T1  - An Algorithm for Shakedown Analysis for Materials with Temperature Dependent Yield Stress
JF  - Proceedings in Applied Mathematics and Mechanics (PAMM). 4 (2004), H. 1
Y1  - 2004
SN  - 1617-7061
SP  - 231
EP  - 233
ER  - 
TY  - JOUR
A1  - Vu, Duc-Khoi
A1  - Staat, Manfred
T1  - An algorithm for shakedown analysis of structure with temperature dependent yield stress
N2  - This work is an attempt to answer the question: How to use convex programming in shakedown analysis of structures made of materials with temperature-dependent properties. Based on recently established shakedown theorems and formulations, a dual relationship between upper and lower bounds of the shakedown limit load is found, an algorithmfor shakedown analysis is proposed. While the original problem is neither convex nor concave, the algorithm presented here has the advantage of employing convex programming tools.
KW  - Einspielen <Werkstoff>
KW  - Temperaturabhängigkeit
KW  - Fließgrenze
KW  - Shakedown
KW  - shakedown analysis
KW  - yield stress
Y1  - 2004
ER  - 
TY  - JOUR
A1  - Tran, Thanh Ngoc
A1  - Staat, Manfred
T1  - An Edge-Based Smoothed Finite Element Method for Primal-Dual Shakedown Analysis of Structures Under Uncertainties
JF  - Limit State of Materials and Structures : Direct Methods 2. Saxcé, Géry de (Hrsg.)
Y1  - 2013
SN  - 978-94-007-5424-9
SP  - 89
EP  - 102
PB  - Springer
CY  - Dordrecht
ER  - 
TY  - CHAP
A1  - Frotscher, Ralf
A1  - Staat, Manfred
T1  - An electromechanical model for cardiac tissue constructs
T2  - Conference proceedings of the YIC GACM 2015 : 3rd ECCOMAS Young Investigators Conference and 6th GACM Colloquium on Computational Mechanics , Aachen, 20.07.2015 - 23.07.2015  / ed.: Stefanie Elgeti ; Jaan-Willem Simon
Y1  - 2015
SP  - 1
EP  - 4
PB  - RWTH Aachen University
CY  - Aachen
ER  - 
TY  - JOUR
A1  - Colombo, Daniele
A1  - Drira, Slah
A1  - Frotscher, Ralf
A1  - Staat, Manfred
T1  - An element-based formulation for ES-FEM and FS-FEM models for implementation in standard solid mechanics finite element codes for 2D and 3D static analysis
JF  - International Journal for Numerical Methods in Engineering
N2  - Edge-based and face-based smoothed finite element methods (ES-FEM and FS-FEM, respectively) are modified versions of the finite element method allowing to achieve more accurate results and to reduce sensitivity to mesh distortion, at least for linear elements. These properties make the two methods very attractive. However, their implementation in a standard finite element code is nontrivial because it requires heavy and extensive modifications to the code architecture. In this article, we present an element-based formulation of ES-FEM and FS-FEM methods allowing to implement the two methods in a standard finite element code with no modifications to its architecture. Moreover, the element-based formulation permits to easily manage any type of element, especially in 3D models where, to the best of the authors' knowledge, only tetrahedral elements are used in FS-FEM applications found in the literature. Shape functions for non-simplex 3D elements are proposed in order to apply FS-FEM to any standard finite element.
KW  - distorted element
KW  - ES-FEM
KW  - FS-FEM
KW  - non-simplex S-FEM elements
KW  - S-FEM
Y1  - 2022
U6  - http://dx.doi.org/10.1002/nme.7126
SN  - 1097-0207
VL  - 124
IS  - 2
SP  - 402
EP  - 433
PB  - Wiley
CY  - Chichester
ER  - 
TY  - JOUR
A1  - Niedermeyer, Angela
A1  - Zhou, Bei
A1  - Dursun, Gözde
A1  - Temiz Artmann, Aysegül
A1  - Markert, Bernd
T1  - An examination of tissue engineered scaffolds in a bioreactor
JF  - Proceedings in Applied Mathematics and Mechanics PAMM
N2  - Replacement tissues, designed to fill in articular cartilage defects, should exhibit the same properties as the native material. The aim of this study is to foster the understanding of, firstly, the mechanical behavior of the material itself and, secondly, the influence of cultivation parameters on cell seeded implants as well as on cell migration into acellular implants. In this study, acellular cartilage replacement material is theoretically, numerically and experimentally investigated regarding its viscoelastic properties, where a phenomenological model for practical applications is developed. Furthermore, remodeling and cell migration are investigated.
Y1  - 2016
U6  - http://dx.doi.org/10.1002/pamm.201610038
SN  - 1617-7061
N1  - Joint Annual Meeting of DMV and GAMM 2016, 87th Annual Meeting of the International Association of Applied Mathematics and Mechanics (GAMM) and Deutsche Mathematiker-Vereinigung (DMV), Braunschweig, DE, Mar 7-11, 2016
VL  - 16
IS  - 1
SP  - 99
EP  - 100
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Tran, Linda
A1  - Mottaghy, K.
A1  - Arlt-Körfer, Sabine
A1  - Waluga, Christian
A1  - Behbahani, Mehdi
T1  - An experimental study of shear-dependent human platelet adhesion and underlying protein-binding mechanisms in a cylindrical Couette system
JF  - Biomedizinische Technik
Y1  - 2017
U6  - http://dx.doi.org/10.1515/bmt-2015-0034
SN  - 0013-5585
VL  - 62
IS  - 4
SP  - 383
EP  - 392
PB  - De Gruyter
CY  - Berlin
ER  - 
TY  - CHAP
A1  - Behbahani, Mehdi
T1  - An Experimental Study of Thrombocyte Reactions in Response to Biomaterial Surfaces and Varying Shear Stress
T2  - Proceedings of the International Conference on Biomedical Engineering and Systems Prague, Czech Republic, August 14-15, 2014
Y1  - 2014
SP  - Paper 125
ER  - 
TY  - JOUR
A1  - Staat, Manfred
T1  - An extension strain type Mohr–Coulomb criterion
JF  - Rock mechanics and rock engineering
N2  - Extension fractures are typical for the deformation under low or no confining pressure. They can be explained by a phenomenological extension strain failure criterion. In the past, a simple empirical criterion for fracture initiation in brittle rock has been developed. In this article, it is shown that the simple extension strain criterion makes unrealistic strength predictions in biaxial compression and tension. To overcome this major limitation, a new extension strain criterion is proposed by adding a weighted principal shear component to the simple criterion. The shear weight is chosen, such that the enriched extension strain criterion represents the same failure surface as the Mohr–Coulomb (MC) criterion. Thus, the MC criterion has been derived as an extension strain criterion predicting extension failure modes, which are unexpected in the classical understanding of the failure of cohesive-frictional materials. In progressive damage of rock, the most likely fracture direction is orthogonal to the maximum extension strain leading to dilatancy. The enriched extension strain criterion is proposed as a threshold surface for crack initiation CI and crack damage CD and as a failure surface at peak stress CP. Different from compressive loading, tensile loading requires only a limited number of critical cracks to cause failure. Therefore, for tensile stresses, the failure criteria must be modified somehow, possibly by a cut-off corresponding to the CI stress. Examples show that the enriched extension strain criterion predicts much lower volumes of damaged rock mass compared to the simple extension strain criterion.
Y1  - 2021
U6  - http://dx.doi.org/10.1007/s00603-021-02608-7
SN  - 1434-453X
N1  - Corresponding author: Manfred Staat
VL  - 54
IS  - 12
SP  - 6207
EP  - 6233
PB  - Springer Nature
CY  - Cham
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Kühn, R.
A1  - Hauger, W.
A1  - Sponagel, Stefan
T1  - An Interpretation of Wolff’s Law
JF  - Biomedizinische Technik. 49 (2004)
Y1  - 2004
SN  - 0932-4666
N1  - Ergänzungsband 2, Teil 2
SP  - 1020
EP  - 1021
ER  - 
TY  - CHAP
A1  - Loeb, Horst W.
A1  - Schartner, Karl-Heinz
A1  - Dachwald, Bernd
A1  - Ohndorf, Andreas
A1  - Seboldt, Wolfgang
T1  - An Interstellar – Heliopause mission using a combination of solar/radioisotope electric propulsion
T2  - Presented at the 32nd International Electric Propulsion Conference
N2  - There is common agreement within the scientific community that in order to understand our local galactic environment it will be necessary to send a spacecraft into the region beyond the solar wind termination shock. Considering distances of 200 AU for a new mission, one needs a spacecraft travelling at a speed of close to 10 AU/yr in order to keep the mission duration in the range of less than 25 yrs, a transfer time postulated by ESA.Two propulsion options for the mission have been proposed and discussed so far: the solar sail propulsion and the ballistic/radioisotope electric propulsion. As a further alternative, we here investigate a combination of solar-electric propulsion and radioisotope-electric propulsion. The solar-electric propulsion stage consists of six 22 cm diameter “RIT-22”ion thrusters working with a high specific impulse of 7377 s corresponding to a positive grid voltage of 5 kV. Solar power of 53 kW BOM is provided by a light-weight solar array. The REP-stage consists of four space-proven 10 cm diameter “RIT-10” ion thrusters that will be operating one after the other for 9 yrs in total. Four advanced radioisotope generators provide 648 W at BOM. The scientific instrument package is oriented at earlier studies. For its mass and electric power requirement 35 kg and 35 W are assessed, respectively. Optimized trajectory calculations, treated in a separate contribution, are based on our “InTrance” method.The program yields a burn out of the REP stage in a distance of 79.6 AU for a usage of 154 kg of Xe propellant. With a C3 = 45,1 (km/s)2 a heliocentric probe velocity of 10 AU/yr is reached at this distance, provided a close Jupiter gravity assist adds a velocity increment of 2.7 AU/yr. A transfer time of 23.8 yrs results for this scenario requiring about 450 kg Xe for the SEP stage, jettisoned at 3 AU. We interpret the SEP/REP propulsion as a competing alternative to solar sail and ballistic/REP propulsion. Omiting a Jupiter fly-by even allows more launch flexibility, leaving the mission duration in the range of the ESA specification.
Y1  - 2011
N1  - 32nd International Electric Propulsion Conference, 11-15 September. Wiesbaden, Germany
SP  - 1
EP  - 7
ER  - 
TY  - JOUR
A1  - Abel, Alexander
A1  - Kahmann, Stephanie Lucina
A1  - Mellon, Stephen
A1  - Staat, Manfred
A1  - Jung, Alexander
T1  - An open-source tool for the validation of finite element models using three-dimensional full-field measurements
JF  - Medical Engineering & Physics
N2  - Three-dimensional (3D) full-field measurements provide a comprehensive and accurate validation of finite element (FE) models. For the validation, the result of the model and measurements are compared based on two respective point-sets and this requires the point-sets to be registered in one coordinate system. Point-set registration is a non-convex optimization problem that has widely been solved by the ordinary iterative closest point algorithm. However, this approach necessitates a good initialization without which it easily returns a local optimum, i.e. an erroneous registration. The globally optimal iterative closest point (Go-ICP) algorithm has overcome this drawback and forms the basis for the presented open-source tool that can be used for the validation of FE models using 3D full-field measurements. The capability of the tool is demonstrated using an application example from the field of biomechanics. Methodological problems that arise in real-world data and the respective implemented solution approaches are discussed.
Y1  - 2020
U6  - http://dx.doi.org/10.1016/j.medengphy.2019.10.015
SN  - 1350-4533
VL  - 77
SP  - 125
EP  - 129
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Pham, Phu Tinh
A1  - Staat, Manfred
T1  - An Upper Bound Algorithm for Limit and Shakedown Analysis of Bounded Linearly Kinematic Hardening Structures
JF  - Limit State of Materials and Structures : Direct Methods 2. Saxcé, Géry de (Hrsg.)
Y1  - 2013
SN  - 978-94-007-5424-9
SP  - 71
EP  - 87
PB  - Springer
CY  - Dordrecht
ER  - 
TY  - JOUR
A1  - Levers, A.
A1  - Staat, Manfred
A1  - Laack, Walter van
T1  - Analyse der Langzeitwirkung der MBST® KernspinResonanzTherapie bei Gonarthrose
T1  - Analysis of the Long-term Effect of the MBST® Nuclear Magnetic Resonance Therapy on Gonarthrosis
N2  - Originalausgabe: Orthopädische Praxis Jg. 47. 2011 H. 11; S. 536-543. Mit freundlicher Genehmigung des Verlags Zusammenfassung: Auf der Basis von Patientenabfragen mittels Fragebogen zum Schmerzempfinden und zur Einschränkung bei Aktivitäten des alltäglichen Lebens wird die Langzeitwirkung der MBST® KernspinResonanz-Therapie bei Gonarthrose untersucht. An der Studie nahmen 39 Patienten teil, bei denen die Therapie bis zu vier Jahre zurückliegt. Neben einer Gesamtbetrachtung wird der Erfolg auch in Abhängigkeit von Alter, Geschlecht und sportlicher Aktivität analysiert. Insgesamt weist die Studie auf eine anhaltende Verbesserung des Gesundheitszustands mit zum Teil deutlicher Schmerzlinderung auch noch nach vier Jahren hin, jedoch mit einer leichten Schmerzzunahme gegen Ende des Untersuchungszeitraums von vier Jahren. Eine tendenziell positivere Wirkung bei Frauen, älteren Menschen oder auch sportlich nicht-aktiven Patienten lässt auf eine mögliche Beeinflussung des Erfolgs der Therapie durch (Über-)Belastung im Alltag schließen. Ein zusätzlich positiver Effekt der Therapie auf die Knochendichte ist ebenfalls denkbar, dies bleibt jedoch offen.
N2  - Original edition: Orthopädische Praxis Vol. 47. 2011 Issue 11; P. 536-543. On the friendly authority of the publisher. Abstract: Based upon a questionnaire for patient-queries regarding pain-sensation and activity-restrictions during everyday task, the long-term effect of MBST® nuclear magnetic resonance therapy is studied in osteoarthritis of the knee. 39 patients, whose therapy dates back up to four years, participated in the study. In addition to an overall view, the success of this therapy is also analyzed regarding age, gender and physical activities. Overall, the study pointed out a sustained improvement in the patients´ local health-status with a significant pain-relief even after four years, but also with a slight increase in pain towards the end of that four-year period. There tends to be more positive effect on women, on elderly of also on even non-sports-active patients which suggest a possible influence by daily (over)-stressing on the success of the therapy. An additional positive effect of the therapy on bone density is also conceivable, however, this remains open.
KW  - Kniegelenkarthrose
KW  - Gonarthrose
KW  - MBST
KW  - Arthosetherapie
KW  - gonarthrosis
KW  - MBST
KW  - arthrosis therapy
Y1  - 2011
ER  - 
TY  - CHAP
A1  - Borggrafe, Andreas
A1  - Ohndorf, Andreas
A1  - Dachwald, Bernd
A1  - Seboldt, Wolfgang
T1  - Analysis of interplanetary solar sail trajectories with attitude dynamics
T2  - Dynamics and Control of Space Systems 2012
N2  - We present a new approach to the problem of optimal control of solar sails for low-thrust trajectory optimization. The objective was to find the required control torque magnitudes in order to steer a solar sail in interplanetary space. A new steering strategy, controlling the solar sail with generic torques applied about the spacecraft body axes, is integrated into the existing low-thrust trajectory optimization software InTrance. This software combines artificial neural networks and evolutionary algorithms to find steering strategies close to the global optimum without an initial guess. Furthermore, we implement a three rotational degree-of-freedom rigid-body attitude dynamics model to represent the solar sail in space. Two interplanetary transfers to Mars and Neptune are chosen to represent typical future solar sail mission scenarios. The results found with the new steering strategy are compared to the existing reference trajectories without attitude dynamics. The resulting control torques required to accomplish the missions are investigated, as they pose the primary requirements to a real on-board attitude control system.
Y1  - 2012
SN  - 978-0-87703-587-9
SP  - 1553
EP  - 1569
PB  - Univelt Inc
CY  - San Diego
ER  - 
TY  - JOUR
A1  - Vu, Duc Khoi
A1  - Staat, Manfred
A1  - Tran, Ich Thinh
T1  - Analysis of pressure equipment by application of the primal-dual theory of shakedown
JF  - Communications in Numerical Methods in Engineering. 23 (2007), H. 3
Y1  - 2007
SN  - 1069-8299
SP  - 213
EP  - 225
ER  - 
TY  - JOUR
A1  - Levers, A.
A1  - Staat, Manfred
A1  - Laack, Walter van
T1  - Analysis of the long-term effect of the MBST® nuclear magnetic resonance therapy on gonarthrosis
JF  - Orthopedic Practice
Y1  - 2016
VL  - 47
IS  - 11
SP  - 521
EP  - 528
ER  - 
TY  - JOUR
A1  - Savitskaya, I.S.
A1  - Kistaubayeva, A.S.
A1  - Ignatova, L.V.
A1  - Digel, Ilya
T1  - Antimicrobial and wound healing properties of a bacterial cellulose based material containing B. subtilis cells
JF  - Heliyon
Y1  - 2019
U6  - http://dx.doi.org/10.1016/j.heliyon.2019.e02592
SN  - 2405-8440
VL  - 5
IS  - 10
SP  - Artikelnummer e02592
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - CHAP
A1  - Frotscher, Ralf
A1  - Raatschen, Hans-Jürgen
A1  - Staat, Manfred
ED  - Eberhardsteiner, J.
T1  - Application of an edge-based smoothed finite element method on geometrically non-linear plates of non-linear material
T2  - Proceedings European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012)
Y1  - 2012
N1  - 6th European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012) Vienna, Austria, September 10-14, 2012
ER  - 
TY  - CHAP
A1  - Gehler, M.
A1  - Ober-Blöbaum, S.
A1  - Dachwald, Bernd
T1  - Application of discrete mechanics and optimal control to spacecraft in non-keplerian motion around small solar system bodies
T2  - Procceedings of the 60th International Astronautical Congress
N2  - Prolonged operations close to small solar system bodies require a sophisticated control logic to minimize propellant mass and maximize operational efficiency. A control logic based on Discrete Mechanics and Optimal Control (DMOC) is proposed and applied to both conventionally propelled and solar sail spacecraft operating at an arbitrarily shaped asteroid in the class of Itokawa. As an example, stand-off inertial hovering is considered, recently identified as a challenging part of the Marco Polo mission. The approach is easily extended to stand-off orbits. We show that DMOC is applicable to spacecraft control at small objects, in particular with regard to the fact that the changes in gravity are exploited by the algorithm to optimally control the spacecraft position. Furthermore, we provide some remarks on promising developments.
KW  - Spacecraft
Y1  - 2009
SN  - 978-161567908-9
N1  - 60th International Astronautical Congress 2009, IAC 2009; Daejeon; South Korea; 12 October 2009 through 16 October 2009
SP  - 1360
EP  - 1371
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Murgan, Ilina
A1  - Beyer, Sonja
A1  - Kotliar, Konstantin
A1  - Weber, Lutz
A1  - Bechtold-Dalla Pozza, Susanne
A1  - Dalla Pozza, Robert
A1  - Wegner, Aharon
A1  - Sitnikova, Diana
A1  - Stock, Konrad
A1  - Heemann, Uwe
A1  - Schmaderer, Christoph
A1  - Baumann, M.
T1  - Arterial and Retinal Vascular Changes in Hypertensive and Prehypertensive Adolescents
JF  - American Journal of Hypertension
Y1  - 2013
SN  - 1941-7225
VL  - 26
IS  - 3
SP  - 400
EP  - 408
PB  - Oxford University Press
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Hunker, Jan L.
A1  - Gossmann, Matthias
A1  - Raman, Aravind Hariharan
A1  - Linder, Peter
T1  - Artificial neural networks in cardiac safety assessment: Classification of chemotherapeutic compound effects on hiPSC-derived cardiomyocyte contractility
JF  - Journal of Pharmacological and Toxicological Methods
Y1  - 2021
U6  - http://dx.doi.org/10.1016/j.vascn.2021.107044
SN  - 1056-8719
VL  - 111
IS  - Article number 107044
PB  - Elsevier
CY  - New York
ER  - 
TY  - JOUR
A1  - Ermolaev, AP
A1  - Erichev, VP
A1  - Antonov, AA
A1  - Grigoryan, GL
A1  - Kotliar, Konstantin
A1  - Levitsky, YV
A1  - Hderi, K
A1  - Mazurova, YV
T1  - Assessing retinal photosensitivity in patients with central vision impairment using a portable perimeter (a preliminary report)
JF  - Vestnik oftalmologii
Y1  - 2019
U6  - http://dx.doi.org/10.17116/oftalma201913503146
N1  - Abstract in Englisch
VL  - 135
IS  - 3
SP  - 46
EP  - 54
ER  - 
TY  - JOUR
A1  - Albracht, Kirsten
A1  - Arampatzis, A.
A1  - Baltzopoulos, V.
T1  - Assessment of muscle volume and physiological cross-sectional area of the human triceps surae muscle in vivo
JF  - Journal of Biomechanics
Y1  - 2008
U6  - http://dx.doi.org/10.1016/j.jbiomech.2008.04.020
SN  - 0021-9290
VL  - 41
SP  - 2211
EP  - 2218
ER  - 
TY  - JOUR
A1  - Behbahani, Mehdi
A1  - Spillner, Jan
A1  - Kopp, Rüdiger
A1  - Finocchiaro, Thomas
T1  - Assistierte Zirkulation : ein Überblick aus klinischer Sicht = Assisted circulation: an overview from a clinical perspective / Spillner, Jan ; Kopp, Rüdiger ; Finocchiaro, Thomas ; Behbahani, Mehdi ; Rossaint, Rolf ; Steinseifer, Ulrich ; Behr, Marek ; Au
JF  - Biomedizinische Technik / Biomedical Engineering. 54 (2009), H. 5
Y1  - 2009
SN  - 0013-5585
N1  - Printausgabe in der Bereichsbibliothek Jülich vorhanden : 63 Z 471
SP  - 255
EP  - 267
PB  - De Gruyter
CY  - Berlin
ER  - 
TY  - CHAP
A1  - Tepecik, Atakan
ED  - Digel, Ilya
ED  - Staat, Manfred
ED  - Trzewik, Jürgen
ED  - Sielemann, Stefanie
ED  - Erni, Daniel
ED  - Zylka, Waldemar
T1  - AstroBioLab: Review of technical and bioanalytical approaches
T2  - 4th YRA MedTech Symposium 2024 : February 1 / 2024 / FH Aachen
N2  - This study presents the concept of AstroBioLab, an autonomous astrobiological field laboratory tailored for the exploration of (sub)glacial habitats. AstroBioLab is an integral component of the TRIPLE (Technologies for Rapid Ice Penetration and subglacial Lake Exploration) DLR-funded project, aimed at advancing astrobiology research through the development and deployment of innovative technologies. AstroBioLab integrates diverse measurement techniques such as fluorescence microscopy, DNA sequencing and fluorescence spectrometry, while leveraging microfluidics for efficient sample delivery and preparation.
Y1  - 2024
SN  - 978-3-940402-65-3
U6  - http://dx.doi.org/10.17185/duepublico/81475
SP  - 33
EP  - 34
PB  - Universität Duisburg-Essen
CY  - Duisburg
ER  - 
TY  - CHAP
A1  - Pirovano, Laura
A1  - Seefeldt, Patric
A1  - Dachwald, Bernd
A1  - Noomen, Ron
T1  - Attitude and Orbital Dynamics Modeling for an Uncontrolled Solar-Sail Experiment in Low-Earth Orbit
T2  - 25th International Symposium on Spaceflight Dynamics, 2015, Munich, Germany
Y1  - 2015
ER  - 
TY  - CHAP
A1  - Pirovano, Laura
A1  - Seefeldt, Patric
A1  - Dachwald, Bernd
A1  - Noomen, Ron
T1  - Attitude and orbital modeling of an uncontrolled solar-sail experiment in low-Earth orbit
T2  - 25th International Symposium on Space Flight Dynamics ISSFD
N2  - Gossamer-1 is the first project of the three-step Gossamer roadmap, the purpose of which is to develop, prove and demonstrate that solar-sail technology is a safe and reliable propulsion technique for long-lasting and high-energy missions. This paper firstly presents the structural analysis performed on the sail to understand its elastic behavior. The results are then used in attitude and orbital simulations. The model considers the main forces and torques that a satellite experiences in low-Earth orbit coupled with the sail deformation. Doing the simulations for varying initial conditions in attitude and rotation rate, the results show initial states to avoid and maximum rotation rates reached for correct and faulty deployment of the sail. Lastly comparisons with the classic flat sail model are carried out to test the hypothesis that the elastic behavior does play a role in the attitude and orbital behavior of the sail
KW  - Solar sail
KW  - Gossamer structures
KW  - Attitude dynamics
KW  - Orbital dynamics
Y1  - 2015
N1  - 25th International Symposium on Space Flight Dynamics ISSFD
October 19 – 23, 2015, Munich, Germany
https://issfd.org/2015/
SP  - 1
EP  - 15
ER  - 
TY  - JOUR
A1  - Pogorelova, Natalia
A1  - Rogachev, Evgeniy
A1  - Digel, Ilya
A1  - Chernigova, Svetlana
A1  - Nardin, Dmitry
T1  - Bacterial Cellulose Nanocomposites: Morphology and Mechanical Properties
JF  - Materials
N2  - Bacterial cellulose (BC) is a promising material for biomedical applications due to its unique properties such as high mechanical strength and biocompatibility. This article describes the microbiological synthesis, modification, and characterization of the obtained BC-nanocomposites originating from symbiotic consortium Medusomyces gisevii. Two BC-modifications have been obtained: BC-Ag and BC-calcium phosphate (BC-Ca3(PO4)2). Structure and physicochemical properties of the BC and its modifications were investigated by scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), atomic force microscopy (AFM), and infrared Fourier spectroscopy as well as by measurements of mechanical and water holding/absorbing capacities. Topographic analysis of the surface revealed multicomponent thick fibrils (150–160 nm in diameter and about 15 µm in length) constituted by 50–60 nm nanofibrils weaved into a left-hand helix. Distinctive features of Ca-phosphate-modified BC samples were (a) the presence of 500–700 nm entanglements and (b) inclusions of Ca3(PO4)2 crystals. The samples impregnated with Ag nanoparticles exhibited numerous roundish inclusions, about 110 nm in diameter. The boundaries between the organic and inorganic phases were very distinct in both cases. The Ag-modified samples also showed a prominent waving pattern in the packing of nanofibrils. The obtained BC gel films possessed water-holding capacity of about 62.35 g/g. However, the dried (to a constant mass) BC-films later exhibited a low water absorption capacity (3.82 g/g). It was found that decellularized BC samples had 2.4 times larger Young’s modulus and 2.2 times greater tensile strength as compared to dehydrated native BC films. We presume that this was caused by molecular compaction of the BC structure.
Y1  - 2020
SN  - 1996-1944
U6  - http://dx.doi.org/10.3390/ma13122849
VL  - 13
IS  - 12
SP  - 1
EP  - 16
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Digel, Ilya
A1  - Akimbekov, Nuraly
A1  - Rogachev, Evgeniy
A1  - Pogorelova, Natalia
T1  - Bacterial cellulose produced by Medusomyces gisevii on glucose and sucrose: biosynthesis and structural properties
JF  - Cellulose
N2  - In this work, the effects of carbon sources and culture media on the production and structural properties of bacterial cellulose (BC) synthesized by Medusomyces gisevii have been studied. The culture medium was composed of different initial concentrations of glucose or sucrose dissolved in 0.4% extract of plain green tea. Parameters of the culture media (titratable acidity, substrate conversion degree etc.) were monitored daily for 20 days of cultivation. The BC pellicles produced on different carbon sources were characterized in terms of biomass yield, crystallinity and morphology by field emission scanning electron microscopy (FE-SEM), atomic force microscopy and X-ray diffraction. Our results showed that Medusomyces gisevii had higher BC yields in media with sugar concentrations close to 10 g L−1 after a 18–20 days incubation period. Glucose in general lead to a higher BC yield (173 g L−1) compared to sucrose (163.5 g L−1). The BC crystallinity degree and surface roughness were higher in the samples synthetized from sucrose. Obtained FE-SEM micrographs show that the BC pellicles synthesized in the sucrose media contained densely packed tangles of cellulose fibrils whereas the BC produced in the glucose media displayed rather linear geometry of the BC fibrils without noticeable aggregates.
KW  - Bacterial cellulose
KW  - Medusomyces gisevi
KW  - Carbon sources
KW  - Culture media
KW  - Cellulose nanostructure
Y1  - 2023
U6  - http://dx.doi.org/10.1007/s10570-023-05592-z
SN  - 1572-882X (Online)
SN  - 0969-0239 (Print)
N1  - Corresponding author: Ilya Digel
PB  - Springer Science + Business Media
CY  - Dordrecht
ER  - 
TY  - JOUR
A1  - Digel, Ilya
A1  - Temiz Artmann, Aysegül
A1  - Nishikawa, K.
A1  - Cook, M.
T1  - Bactericidal effects of plasma-generated cluster ions
JF  - Medical and Biological Engineering and Computing. 43 (2005), H. 6
Y1  - 2005
SN  - 1741-0444
SP  - 800
EP  - 807
ER  - 
TY  - CHAP
A1  - Staat, Manfred
A1  - Heitzer, M.
T1  - Basis reduction technique for limit and shakedown problems
T2  - Numerical Methods for Limit and Shakedown Analysis. Deterministic and Probabilistic Approach. NIC Series Vol. 15 / Ed. by Staat, M.; Heitzer, M.
Y1  - 2003
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0001-2018112115
SN  - 3-00-010001-6
SP  - 1
EP  - 55
PB  - John von Neumann Institute for Computing (NIC)
CY  - Jülich
ER  - 
TY  - CHAP
A1  - Lanzl, I.
A1  - Seidova, S.-F.
A1  - Dühring, C. von
A1  - Kotliar, Konstantin
ED  - Erb, Carl
T1  - Befunde der dynamischen Gefäßanalyse am Auge bei Gesunden und Glaukom-Patienten mit praxisrelevanter Bedeutung
T2  - Mikrozirkulation beim Glaukom
Y1  - 2009
N1  - Search on Glaucoma
SP  - 33
EP  - 39
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - PAT
A1  - Staat, Manfred
A1  - Horbach, Andreas
A1  - Gatzweiler, Karl-Heinz
T1  - Biaxiales Materialprüfsystem und Verfahren zu dessen Anwendung
N2  - System und Verfahren zur Durchführung von Messungen biaxialer und kreuzförmiger Zugversuche, wobei ein Weg oder eine Kraft auf eine Materialprobe über mindestens zwei Nadelarme mit Nadeln geleitet wird, die in einem Gehäuse gelagert sind, wobei die Arme und/oder Nadelarme für eine ungehinderte Querkontraktion bei gleichmäßiger Lasteinleitung um eine Achse drehbar gelagert und seitlich auslenkbar sind.
Y1  - 2019
N1  - Patent DE102017116067
ER  - 
TY  - JOUR
A1  - Mansurov, Z.
A1  - Digel, Ilya
A1  - Biisenbaev, M.
A1  - Savistkaya, I.
A1  - Kistaubaeva, A.
A1  - Akimbekov, N.
A1  - Zhubanova, A.
T1  - Bio-composite material on the basis of carbonized rice husk in biomedicine and environmental applications
JF  - Eurasian Chemico-Technological Journal
Y1  - 2012
U6  - http://dx.doi.org/10.18321/ectj105
SN  - 2522-4867
VL  - 14
IS  - 2
SP  - 115
EP  - 131
PB  - Institute of Combustion Problems
CY  - Almaty
ER  - 
TY  - JOUR
A1  - Uysal, Karya
A1  - Creutz, Till
A1  - Firat, Ipek Seda
A1  - Artmann, Gerhard
A1  - Teusch, Nicole
A1  - Temiz Artmann, Aysegül
T1  - Bio-functionalized ultra-thin, large-area and waterproof silicone membranes for biomechanical cellular loading and compliance experiments
JF  - Polymers
N2  - Biocompatibility, flexibility and durability make polydimethylsiloxane (PDMS) membranes top candidates in biomedical applications. CellDrum technology uses large area, <10 µm thin membranes as mechanical stress sensors of thin cell layers. For this to be successful, the properties (thickness, temperature, dust, wrinkles, etc.) must be precisely controlled. The following parameters of membrane fabrication by means of the Floating-on-Water (FoW) method were investigated: (1) PDMS volume, (2) ambient temperature, (3) membrane deflection and (4) membrane mechanical compliance. Significant differences were found between all PDMS volumes and thicknesses tested (p < 0.01). They also differed from the calculated values. At room temperatures between 22 and 26 °C, significant differences in average thickness values were found, as well as a continuous decrease in thicknesses within a 4 °C temperature elevation. No correlation was found between the membrane thickness groups (between 3–4 µm) in terms of deflection and compliance. We successfully present a fabrication method for thin bio-functionalized membranes in conjunction with a four-step quality management system. The results highlight the importance of tight regulation of production parameters through quality control. The use of membranes described here could also become the basis for material testing on thin, viscous layers such as polymers, dyes and adhesives, which goes far beyond biological applications.
Y1  - 2022
SN  - 2073-4360
VL  - 14
IS  - 11
SP  - 2213
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Akimbekov, N. S.
A1  - Digel, Ilya
A1  - Tastambek, K. T.
A1  - Zhubanova, A. A.
T1  - Biocompatibility of carbonized rice husk with a rat heart cells line H9c2
JF  - Experimental Biology
Y1  - 2013
SN  - 1563-0218
N1  - Original in russischer Sprache
VL  - 59
IS  - 3/1
SP  - 23
EP  - 25
ER  - 
TY  - CHAP
A1  - Mansurov, Zulkhair A.
A1  - Jandosov, Jakpar
A1  - Chenchik, D.
A1  - Azat, Seitkhan
A1  - Savitskaya, Irina S.
A1  - Kistaubaeva, Aida
A1  - Akimbekov, Nuraly
A1  - Digel, Ilya
A1  - Zhubanova, Azhar Achmet
T1  - Biocomposite Materials Based on Carbonized Rice Husk in Biomedicine and Environmental Applications
T2  - Carbon Nanomaterials in Biomedicine and the Environment
N2  - This chapter describes the prospects for biomedical and environmental engineering applications of heterogeneous materials based on nanostructured carbonized rice husk. Efforts in engineering enzymology are focused on the following directions: development and optimization of immobilization methods leading to novel biotechnological and biomedical applications; construction of biocomposite materials based on individual enzymes, multi-enzyme complexes and whole cells, targeted on realization of specific industrial processes. Molecular biological and biochemical studies on cell adhesion focus predominantly on identification, isolation and structural analysis of attachment-responsible biological molecules and their genetic determinants. The chapter provides a short overview of applications of the biocomposite materials based of nanostructured carbonized adsorbents. It emphasizes that further studies and better understanding of the interactions between CNS and microbial cells are necessary. The future use of living cells as biocatalysts, especially in the environmental field, needs more systematic investigations of the microbial adsorption phenomenon.
Y1  - 2020
SN  - 978-981-4800-27-3
U6  - http://dx.doi.org/10.1201/9780429428647-2
SP  - 3
EP  - 32
PB  - Jenny Stanford Publishing Pte. Ltd.
CY  - Singapore
ER  - 
TY  - BOOK
A1  - Artmann, Gerhard
T1  - Bioengineering in Cell and Tissue Research / Artmann, Gerhard M. ; Chien, Shu (Eds.)
Y1  - 2008
SN  - 978-3-540-75408-4
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Maggakis-Kelemen, C.
A1  - Bork, M.
A1  - Kayser, Peter
A1  - Biselli, Manfred
A1  - Artmann, Gerhard
T1  - Biological and mechanical quality of red blood cells cultured from human umbilical cord blood stem cells
JF  - Medical and biological engineering and computing. 41 (2003), H. 3
Y1  - 2003
SN  - 0140-0118
SP  - 350
EP  - 356
ER  - 
TY  - BOOK
A1  - Artmann, Gerhard
A1  - Temiz Artmann, Aysegül
A1  - Zhubanova, Azhar A.
A1  - Digel, Ilya
ED  - Artmann, Gerhard
ED  - Temiz Artmann, Aysegül
ED  - Zhubanova, Azhar A.
ED  - Digel, Ilya
T1  - Biological, physical and technical basics of cell engineering
Y1  - 2018
SN  - 978-981-10-7903-0
PB  - Springer
CY  - Singapore
ER  - 
TY  - THES
A1  - Föckler, Nicole
T1  - Biomarker zur Prognose von Frühgeburten : ein biomedizintechnischer Ansatz
Y1  - 2016
U6  - http://dx.doi.org/10.4126/FRL01-006401575
N1  - Dissertation, Köln, Universität zu Köln, 2016
PB  - Deutsche Zentralbibliothek für Medizin
CY  - Köln
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Koshitz, I. N.
A1  - Svetlowa, O. V.
A1  - Makarov, F. N.
T1  - Biomechanical analysis of traditional and contemporary conceptions on pathogenesis of the primary open angle glaucoma / Koshitz, I. N. ; Svetlova, O. V. ; Kotliar, K. E. ; Makarov, F. N. ;  Smolnikov, B. A.
JF  - Glaukoma (2005)
Y1  - 2005
N1  - Original in Russisch
SP  - 41
EP  - 63
PB  - -
ER  - 
TY  - JOUR
A1  - Horbach, Andreas
A1  - Staat, Manfred
A1  - Perez-Viana, Daniel
A1  - Simmen, Hans-Peter
A1  - Neuhaus, Valentin
A1  - Pape, Hans-Christoph
A1  - Prescher, Andreas
A1  - Ciritsis, Bernhard
T1  - Biomechanical in vitro examination of a standardized low-volume tubular femoroplasty
JF  - Clinical Biomechanics
N2  - Background
Osteoporosis is associated with the risk of fractures near the hip. Age and comorbidities increase the perioperative risk. Due to the ageing population, fracture of the proximal femur also proves to be a socio-economic problem. Preventive surgical measures have hardly been used so far.

Methods
10 pairs of human femora from fresh cadavers were divided into control and low-volume femoroplasty groups and subjected to a Hayes fall-loading fracture test. The results of the respective localization and classification of the fracture site, the Singh index determined by computed tomography (CT) examination and the parameters in terms of fracture force, work to fracture and stiffness were evaluated statistically and with the finite element method. In addition, a finite element parametric study with different position angles and variants of the tubular geometry of the femoroplasty was performed.

Findings
Compared to the control group, the work to fracture could be increased by 33.2%. The fracture force increased by 19.9%. The used technique and instrumentation proved to be standardized and reproducible with an average poly(methyl methacrylate) volume of 10.5 ml. The parametric study showed the best results for the selected angle and geometry.

Interpretation
The cadaver studies demonstrated the biomechanical efficacy of the low-volume tubular femoroplasty. The numerical calculations confirmed the optimal choice of positioning as well as the inner and outer diameter of the tube in this setting. The standardized minimally invasive technique with the instruments developed for it could be used in further comparative studies to confirm the measured biomechanical results.
Y1  - 2020
U6  - http://dx.doi.org/10.1016/j.clinbiomech.2020.105104
VL  - 80
IS  - Art. 105104
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Lanzl, I. M.
T1  - Biomechanical modeling of the aqueous humor outflow after non-penetrating glaucoma filtration surgery in the human eye
JF  - Acta of bioengineering and biomechanics
Y1  - 2002
SN  - 1509-409X
VL  - Vol. 4
IS  - Suppl. 1
SP  - 728
EP  - 729
ER  - 
TY  - CHAP
A1  - Kahmann, Stephanie Lucina
A1  - Uschok, Stephan
A1  - Wegmann, Kilian
A1  - Müller, Lars-P.
A1  - Staat, Manfred
T1  - Biomechanical multibody model with refined kinematics of the elbow
T2  - 6th European Conference on Computational Mechanics (ECCM 6), 7th European Conference on Computational Fluid Dynamics (ECFD 7), 11-15 June 2018, Glasgow, UK
N2  - The overall objective of this study is to develop a new external fixator, which closely maps the native kinematics of the elbow to decrease the joint force resulting in reduced rehabilitation time and pain. An experimental setup was designed to determine the native kinematics of the elbow during flexion of cadaveric arms. As a preliminary study, data from literature was used to modify a published biomechanical model for the calculation of the joint and muscle forces. They were compared to the original model and the effect of the kinematic refinement was evaluated. Furthermore, the obtained muscle forces were determined in order to apply them in the experimental setup. The joint forces in the modified model differed slightly from the forces in the original model. The muscle force curves changed particularly for small flexion angles but their magnitude for larger angles was consistent.
Y1  - 2018
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Svetlova, O. V.
A1  - Sourjikov, A. V.
A1  - Zaseeva, M. V.
T1  - Biomechanical peculiarities of aqueous humor production system and outflow regulation system / Svetlova, O. V. ; Sourjikov, A. V. ; Kotliar, K. E. ; Zaseeva, M. V. ; Shukhaev, S. V. ; Koshitz, I. N.
JF  - Glaukoma (2004)
Y1  - 2004
N1  - Original in Russisch
SP  - 66
EP  - 76
PB  - -
ER  - 
TY  - CHAP
A1  - Jabbari, Medisa
A1  - Bhattarai, Aroj
A1  - Anding, Ralf
A1  - Staat, Manfred
ED  - Erni, Daniel
ED  - Fischerauer, Alice
ED  - Himmel, Jörg
ED  - Seeger, Thomas
ED  - Thelen, Klaus
T1  - Biomechanical simulation of different prosthetic meshes for repairing uterine/vaginal vault prolapse
T2  - 2nd YRA MedTech Symposium 2017 : June 8th - 9th / 2017 / Hochschule Ruhr-West
Y1  - 2017
SN  - 978-3-9814801-9-1
U6  - http://dx.doi.org/10.17185/duepublico/43984
N1  - A young researchers track of the 7th IEEE Workshop & SENSORICA 2017
SP  - 118
EP  - 119
PB  - Universität Duisburg-Essen
CY  - Duisburg
ER  - 
TY  - CHAP
A1  - Bhattarai, Aroj
A1  - Frotscher, Ralf
A1  - Staat, Manfred
T1  - Biomechanical study of the female pelvic floor dysfunction using the finite element method
T2  - Conference proceedings of the YIC GACM 2015 : 3rd ECCOMAS Young Investigators Conference and 6th GACM Colloquium on Computational Mechanics , Aachen , Germany, 20.07.2015 - 23.07.2015  / ed.: Stefanie Elgeti ; Jaan-Willem Simon
Y1  - 2015
SP  - 1
EP  - 4
PB  - RWTH Aachen University
CY  - Aachen
ER  -