TY  - JOUR
A1  - Kern, Alexander
A1  - Kaiser, Ludwig
T1  - Auswirkungen des EMVG auf leittechnische Einrichtungen in großflächigen Industrieanlagen / von Ludwig Kaiser ; Alexander Kern
JF  - ETZ : Elektrotechnik + Automation. 116 (1995), H. 9
Y1  - 1995
SN  - 0170-1711
N1  - 2. ISSN: 0948-7387 ; In der Bibliothek unter 23 Z 133 (Eupener Str.) und 63 ZS 035 (Jülich) vorhanden.
SP  - 16
EP  - 18
ER  - 
TY  - JOUR
A1  - Kern, Alexander
A1  - Heidler, Fridolin
A1  - Zischank, Wolfgang J.
A1  - Frentzel, Ralf
T1  - Lightning current distribution and coupling to control cables in power plants or large industrial facilites
Y1  - 2002
N1  - International Conference on Grounding and Earthing <2002, Rio de Janeiro>
ER  - 
TY  - JOUR
A1  - Kern, Alexander
A1  - Heidler, Fridolin
A1  - Zahlmann, P.
A1  - Zischank, Wolfgang J.
T1  - Blitzschutz
JF  - ETZ : Elektrotechnik + Automation. 114 (1993), H. 2
Y1  - 1993
SN  - 0170-1711
N1  - 2. ISSN: 0948-7387
ER  - 
TY  - JOUR
A1  - Kern, Alexander
A1  - Heidler, F.
A1  - Zischank, W.
T1  - Induced overvoltages in cable ducts taking into account the current flow into earth / F. Heidler ; W. Zischank ... A. Kern ...
JF  - Conference proceedings : 14th - 18th September 1998, [Burlington Hotel, Birmingham, United Kingdom] / organised by: School of Engineering and Advanced Technology, Staffordshire University, United Kingdom
Y1  - 1998
N1  - International Conference on Lightning Protection <24, 1998, Birmingham> ; School of Engineering and Advanced Technology <Stafford> ; ICLP <4, 1998, Birmingham>
CY  - Birmingham
ER  - 
TY  - JOUR
A1  - Kern, Alexander
A1  - Hasse, P.
A1  - Wiesinger, J.
A1  - Zischank, Wolfgang J.
T1  - Aktuelles aus der Blitzforschung
JF  - ETZ : Elektrotechnik + Automation. 112 (1991), H. 1
Y1  - 1991
SN  - 0170-1711
N1  - 2. ISSN: 0948-7387
ER  - 
TY  - JOUR
A1  - Kern, Alexander
A1  - Frentzel, Ralf
A1  - Behrens, Jörg
T1  - Simulation of the transient voltages in the auxiliary power network of a large power plant in case of a direct lightning strike to the high-voltage overhead transmission line
Y1  - 2010
N1  - 30th International Conference on Lightning Protection, Cagliari (Italien), 2010
SP  - 749-1
EP  - 749-7
ER  - 
TY  - JOUR
A1  - Kern, Alexander
A1  - Drumm, F.
T1  - Survey of the lightning threat for aircraft based on natural lightning data and fixed in the German Standard DIN VG 95371 / Part 10
JF  - Proceedings of the 1994 International Aerospace and Ground Conference on Lightning and Static Electricity : May 14 - 27, 1994, Bundesakademie für Wehrverwaltung und Wehrtechnik Mannheim ; final report / [conference chairman Jan Luiken TerHaseborg]
Y1  - 1994
N1  - International Aerospace and Ground Conference on Lightning and Static Electricity <16, 1994, Mannheim>
PB  - Bundesakad. für Wehrverwaltung und Wehrtechnik
CY  - Mannheim
ER  - 
TY  - JOUR
A1  - Kern, Alexander
A1  - Dikta, Gerhard
A1  - Krichel, Frank
T1  - Zur Wahrscheinlichkeit für Schäden an elektrischen und elektronischen Einrichtungen durch indirekte Blitzeinschläge - Auswertung von Schadensstatistiken, analytischen und numerischen Berechnungen
JF  - 7. VDE-ABB-Blitzschutztagung : Vorträge der VDE-ABB-Fachtagung vom 15. bis 16. November 2007 in Neu-Ulm / Veranst.: Ausschuss für Blitzschutz und Blitzforschung (ABB) im VDE, Verband der Elektrotechnik, Elektronik, Informationstechnik e.V. Wiss. Tagungsltg.: K. Stimper
Y1  - 2007
SN  - 978-3-8007-3062-9
N1  - VDE-Fachbericht ; 64  ; Blitzschutztagung <7, 2007, Neu-Ulm>
SP  - 1
EP  - 9
PB  - VDE-Verl.
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Kern, Alexander
A1  - Dikta, Gerhard
T1  - Bewerten von Schäden durch Blitzeinwirkungen
JF  - Elektropraktiker. 62 (2008), H. 4
Y1  - 2008
SN  - 0013-5569
SP  - 338
EP  - 342
ER  - 
TY  - JOUR
A1  - Kern, Alexander
A1  - Braun, Christian
T1  - Neuerungen bei der Blitzschutznorm. Teil 2
JF  - etz Elektrotechnik und Automation
Y1  - 2013
SN  - 0170-1711
N1  - Printausg. in der Bibliothek der FH Aachen vorhanden: 23 Z 133 ; 63 ZS 035
VL  - Bd. 134
IS  - H. 8
SP  - 66
EP  - 69
PB  - VDE-Verlag
CY  - Wuppertal
ER  - 
TY  - JOUR
A1  - Kern, Alexander
A1  - Beierl, O.
A1  - Zischank, W.
T1  - DIN EN 62 305-3 - Berechnung des Trennungsabstands (Anmerkungen zur Anwendung der Berechnungsverfahren und vereinfachte Verfahren zur Abschätzung der Stromaufteilung) / Kern, A. ; Beierl, O. ; Zischank, W.
JF  - Elektropraktiker. 63 (2009), H. 3
Y1  - 2009
SN  - 0013-5569
SP  - 218
EP  - 222
PB  - HUSS-MEDIEN GmbH
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Kern, Alexander
T1  - Simulation and measurement of melting effects on metal sheets caused by direct lightning strikes
JF  - 1991 International Aerospace and Ground Conference on Lightning and Static Electricity : proceedings of a conference ... held at Cocoa Beach, Florida, April 16-19, 1991 / NASA
Y1  - 1991
N1  - International Aerospace and Ground Conference on Lightning and Static Electricity <1991, Cocoa Beach, Fla.> ; United States / National Aeronautics and Space Administration
CY  - Washington, DC
ER  - 
TY  - JOUR
A1  - Kern, Alexander
T1  - The heating of metal sheets caused by direct lightning strikes-model and measurement
JF  - 20th ICPL / International Conference on Lightning Protection, Congress-Center Casino Interlaken, Switzerland, September 24-28, 1990 = Internationale Blitzschutzkonferenz, Congress-Center Casino Interlaken, Schweiz, 24.-28. September 1990
Y1  - 1990
N1  - International Conference on Lightning Protection <20, 1990, Interlaken> ; Internationale Blitzschutzkonferenz <20, 1990, Interlaken>
PB  - Schweizerischer Elektrotechnischer Verein
CY  - [Zürich]
ER  - 
TY  - JOUR
A1  - Kern, Alexander
T1  - Beispiele für EMV-Maßnahmen in großflächigen Anlagen
JF  - EMV von Gebäuden, Anlagen und Geräten : praktische Umsetzung der technischen, wirtschaftlichen und gesetzlichen Anforderungen für die CE-Kennzeichnung / Anton Kohling (Hrsg.). Gerd Balzer...
Y1  - 1998
SN  - 3-8007-2261-5
PB  - VDE-Verl.
CY  - Berlin [u.a.]
ER  - 
TY  - JOUR
A1  - Kern, Alexander
T1  - Time dependent temperature distribution in metal sheets caused by direct lightning strikes
JF  - Proceedings / Sixth International Symposium on High Voltage Engineering : 28. August - 1. September, 1989, Westin Canal Place Hotel, New Orleans, Louisiana, USA
Y1  - 1989
N1  - International Symposium on High Voltage Engineering <6, 1989, New Orleans, La.>
PB  - Mississippi State University
CY  - Mississippi State, Miss.
ER  - 
TY  - JOUR
A1  - Kern, Alexander
T1  - Physik der Blitzentladung und Blitzstrom-Parameter bei natürlichen Blitzen
Y1  - 1993
N1  - Wehrtechnisches Symposium Elektromagnetische Verträglichkeit <5, 1993, Mannheim>
ER  - 
TY  - JOUR
A1  - Kern, Alexander
T1  - Blitz-Störschutz als Maßnahme der EMV am Beispiel einer ausgedehnten Industrieanlage
Y1  - 1995
N1  - Forum für Sachverständige, Fa. Dehn + Söhne <2, 1995, Nürnberg>
ER  - 
TY  - JOUR
A1  - Kern, Alexander
T1  - Blitz-Schutzzonen mit Schirmungen und Schnittstellen
JF  - Blitzschutz für Gebäude und elektrische Anlagen : Vorträge der VDE/ABB-Fachtagung am 29. Februar und 1. März 1996 in Kassel / Veranst.: Ausschuß Blitzschutz und Blitzforschung (ABB) im VDE-Verband Dt. Elektrotechniker e.V. Wiss. Tagungsleit.: F. Noack. - (Verband Deutscher Elektrotechniker: VDE-Fachbericht ; 49)
Y1  - 1996
SN  - 3-8007-2161-9
N1  - Blitzschutztagung <1, 1996, Kassel> ; Verband Deutscher Elektrotechniker / Ausschuss für Blitzschutz und Blitzforschung
PB  - VDE-Verl.
CY  - Berlin [u.a.]
ER  - 
TY  - JOUR
A1  - Kern, Alexander
T1  - Ertüchtigung des Blitzschutzsystems für ein Bürogebäude auf der Basis von VDE V 0185 Teil 100 (ENV 61024-1) und VDE 0185 Teil 103 (IEC 1312-1)
Y1  - 1998
N1  - Forum Verband Deutscher Blitzschutzfirmen e.V. <1998, Köln>
ER  - 
TY  - JOUR
A1  - Kern, Alexander
T1  - Aktueller Stand zu Risikoabschätzungen bei Blitzeinschlägen - Was ist neu in der IEC 61662 Edition 2?
Y1  - 2000
N1  - Forum Verband Deutscher Blitzschutzfirmen e.V. <2000, Köln>
ER  - 
TY  - JOUR
A1  - Kern, Alexander
T1  - Neue deutsche Blitzschutz-Normung. Reihe DIN EN 62305 / VDE 01 85-305-x:2006
JF  - Der Eisenbahningenieur. 58 (2007), H. 8
Y1  - 2007
SN  - 0013-2810
N1  - in der Bereichsbibliothek Bayernallee vorhanden
SP  - 18
EP  - 22
ER  - 
TY  - JOUR
A1  - Kern, Alexander
T1  - Die neuen Blitzschutznormen der Reihe DIN EN 62305 (VDE 0185-305-x)
JF  - ETZ : Elektrotechnik + Automation. 2006 (2006), H. 2
Y1  - 2006
SN  - 0170-1711
N1  - 2. ISSN: 0948-7387 ; In der Bibliothek unter 23 Z 133 (Eupener Str.) und 63 ZS 035 (Jülich) vorhanden.
SP  - 42
EP  - 45
ER  - 
TY  - JOUR
A1  - Kern, Alexander
T1  - Überarbeitung der Blitzschutznorm IEC 62305
JF  - Elektropraktiker. 63 (2009), H. 4
Y1  - 2009
SN  - 0013-5569
SP  - 391
EP  - 394
ER  - 
TY  - JOUR
A1  - Kern, Alexander
T1  - Blitz- und Überspannungsschutz von Kernkraftwerken - Nachweisführung der ausreichenden Sicherheit für leittechnische Einrichtungen auch bei Blitzeinschlägen mit extremen Parametern
JF  - Atw. International Journal for Nuclear Power
N2  - Für das Auftreten extremer Wetterereignisse werden für Kernkraftwerke Eintrittshäufigkeiten für nicht mehr beherrschbare Zustände von unter 10⁻⁴/a gefordert. Dies gilt auch für die Einwirkung von Blitzeinschlägen. Die bisherige Nachweisführung zu Blitz- und Überspannungsschutz eines KKW in Deutschland ist deterministisch. In diesem Bericht werden das Vorgehen für einen entsprechenden Nachweis für leittechnische Einrichtungen der Sicherheitstechnik von KKW, der zur geforderten Zielgröße der Eintrittshäufigkeit führt. Die Ergebnisse werden zusammenfassend bewertet.
Y1  - 2016
SN  - 1431-5254
VL  - 61
IS  - 8/9
SP  - 534
EP  - 543
PB  - Inforum
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Kempt, Hendrik
A1  - Freyer, Nils
A1  - Nagel, Saskia K.
T1  - Justice and the normative standards of explainability in healthcare
JF  - Philosophy & Technology
N2  - Providing healthcare services frequently involves cognitively demanding tasks, including diagnoses and analyses as well as complex decisions about treatments and therapy. From a global perspective, ethically significant inequalities exist between regions where the expert knowledge required for these tasks is scarce or abundant. One possible strategy to diminish such inequalities and increase healthcare opportunities in expert-scarce settings is to provide healthcare solutions involving digital technologies that do not necessarily require the presence of a human expert, e.g., in the form of artificial intelligent decision-support systems (AI-DSS). Such algorithmic decision-making, however, is mostly developed in resource- and expert-abundant settings to support healthcare experts in their work. As a practical consequence, the normative standards and requirements for such algorithmic decision-making in healthcare require the technology to be at least as explainable as the decisions made by the experts themselves. The goal of providing healthcare in settings where resources and expertise are scarce might come with a normative pull to lower the normative standards of using digital technologies in order to provide at least some healthcare in the first place. We scrutinize this tendency to lower standards in particular settings from a normative perspective, distinguish between different types of absolute and relative, local and global standards of explainability, and conclude by defending an ambitious and practicable standard of local relative explainability.
KW  - Clinical decision support systems
KW  - Justice
KW  - Medical AI
KW  - Explainability
KW  - Normative standards
Y1  - 2022
U6  - https://doi.org/10.1007/s13347-022-00598-0
VL  - 35
IS  - Article number: 100
SP  - 1
EP  - 19
PB  - Springer Nature
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Kellner, Katja
A1  - Lind, Thorsten Patric
T1  - Zur Verjährung des Anspruchs aus § 32b GmbHG
JF  - Zeitschrift für das gesamte Insolvenzrecht : ZInsO
Y1  - 2006
SN  - 1615-8032
IS  - H. 8
SP  - 413
EP  - 414
ER  - 
TY  - JOUR
A1  - Keller, Johannes
A1  - Rath, Volker
A1  - Bruckmann, Johanna
A1  - Mottaghy, Darius
A1  - Clauser, Christoph
A1  - Wolf, Andreas
A1  - Seidler, Ralf
A1  - Bücker, H. Martin
A1  - Klitzsch, Norbert
T1  - SHEMAT-Suite: An open-source code for simulating flow, heat and species transport in porous media
JF  - SoftwareX
N2  - SHEMAT-Suite is a finite-difference open-source code for simulating coupled flow, heat and species transport in porous media. The code, written in Fortran-95, originates from geoscientific research in the fields of geothermics and hydrogeology. It comprises: (1) a versatile handling of input and output, (2) a modular framework for subsurface parameter modeling, (3) a multi-level OpenMP parallelization, (4) parameter estimation and data assimilation by stochastic approaches (Monte Carlo, Ensemble Kalman filter) and by deterministic Bayesian approaches based on automatic differentiation for calculating exact (truncation error-free) derivatives of the forward code.
Y1  - 2020
U6  - https://doi.org/10.1016/j.softx.2020.100533
SN  - 2352-7110
VL  - 12
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Kearney, David W.
A1  - Kelly, Bruce
A1  - Herrmann, Ulf
A1  - Cable, R.
A1  - Pacheco, J.
A1  - Mahoney, R.
A1  - Price, Henry
A1  - Blake, D.
A1  - Nava, P.
A1  - Potrovitza, N.
T1  - Engineering Aspects of a Molten Salt Heat Transfer Fluid in a Trough Solar Field
JF  - Energy : the international journal
Y1  - 2002
U6  - https://doi.org/10.1016/S0360-5442(03)00191-9
SN  - 0360-5442
N1  - SolarPACES 2002, Zürich, Switzerland, 4–6 September 2002
VL  - 29
IS  - 5-6 (Special Issue SolarPaces)
SP  - 861
EP  - 870
ER  - 
TY  - JOUR
A1  - Kearney, D.
A1  - Herrmann, Ulf
A1  - Nava, P.
A1  - Kelly, B.
A1  - Mahoney, R.
A1  - Pacheco, J.
A1  - Cable, R.
A1  - Potrovitza, N.
A1  - Blake, D.
A1  - Price, H.
T1  - Assessment of a Molten Salt Heat Transfer Fluid in a Parabolic Trough Solar Field
JF  - Journal of Solar Energy Engineering
Y1  - 2003
U6  - https://doi.org/10.1115/1.1565087
SN  - 1528-8986
VL  - 125
IS  - 2
SP  - 170
EP  - 176
ER  - 
TY  - JOUR
A1  - Kaul, D. K.
A1  - Koshkaryev, A.
A1  - Artmann, Gerhard
A1  - Barshtein, G.
A1  - Yedgar, S.
T1  - Additive effect of red blood cell rigidity and adherence to endothelial cells in inducing vascular resistance
JF  - American Journal of Physiology : Heart and Circulation Physiology . 295 (2008), H. 4
Y1  - 2008
SN  - 1522-1539
VL  - 295
IS  - 4
SP  - H1788
EP  - H1793
ER  - 
TY  - JOUR
A1  - Katz, Evgeny
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
T1  - Enzyme-based logic gates and circuits - analytical applications and interfacing with electronics
JF  - Analytical and Bioanalytical Chemistry
N2  - The paper is an overview of enzyme-based logic gates and their short circuits, with specific examples of Boolean AND and OR gates, and concatenated logic gates composed of multi-step enzyme-biocatalyzed reactions. Noise formation in the biocatalytic reactions and its decrease by adding a “filter” system, converting convex to sigmoid response function, are discussed. Despite the fact that the enzyme-based logic gates are primarily considered as components of future biomolecular computing systems, their biosensing applications are promising for immediate practical use. Analytical use of the enzyme logic systems in biomedical and forensic applications is discussed and exemplified with the logic analysis of biomarkers of various injuries, e.g., liver injury, and with analysis of biomarkers characteristic of different ethnicity found in blood samples on a crime scene. Interfacing of enzyme logic systems with modified electrodes and semiconductor devices is discussed, giving particular attention to the interfaces functionalized with signal-responsive materials. Future perspectives in the design of the biomolecular logic systems and their applications are discussed in the conclusion.
Y1  - 2017
U6  - https://doi.org/10.1007/s00216-016-0079-7
SN  - 1618-2650
VL  - 409
SP  - 81
EP  - 94
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Kassab, T.
A1  - Han, Y.
A1  - Poghossian, Arshak
A1  - Ingebrandt, S.
A1  - Offenhäusser, A.
A1  - Schöning, Michael Josef
T1  - Detection of layerby-layer adsorbed polyelectrolytes by means of field-effect based capacitive EIS structures
JF  - Biomedizinische Technik. 49 (2004), H. 2
Y1  - 2004
SN  - 0932-4666
SP  - 1034
EP  - 1035
ER  - 
TY  - JOUR
A1  - Kasch, Susanne
A1  - Schmidt, Thomas
A1  - Jahn, Simon
A1  - Eichler, Fabian
A1  - Thurn, Laura
A1  - Bremen, Sebastian
T1  - Lösungsansätze und Verfahrenskonzepte zum Laserstrahlschmelzen von Glas
JF  - Schweissen und Schneiden
Y1  - 2021
SN  - 0036-7184
VL  - 73
IS  - Heft 1-2
SP  - 32
EP  - 39
PB  - DVS Verlag
CY  - Düsseldorf
ER  - 
TY  - JOUR
A1  - Karschuck, Tobias
A1  - Poghossian, Arshak
A1  - Ser, Joey
A1  - Tsokolakyan, Astghik
A1  - Achtsnicht, Stefan
A1  - Wagner, Patrick
A1  - Schöning, Michael Josef
T1  - Capacitive model of enzyme-modified field-effect biosensors: Impact of enzyme coverage
JF  - Sensors and Actuators B: Chemical
N2  - Electrolyte-insulator-semiconductor capacitors (EISCAP) belong to field-effect sensors having an attractive transducer architecture for constructing various biochemical sensors. In this study, a capacitive model of enzyme-modified EISCAPs has been developed and the impact of the surface coverage of immobilized enzymes on its capacitance-voltage and constant-capacitance characteristics was studied theoretically and experimentally. The used multicell arrangement enables a multiplexed electrochemical characterization of up to sixteen EISCAPs. Different enzyme coverages have been achieved by means of parallel electrical connection of bare and enzyme-covered single EISCAPs in diverse combinations. As predicted by the model, with increasing the enzyme coverage, both the shift of capacitance-voltage curves and the amplitude of the constant-capacitance signal increase, resulting in an enhancement of analyte sensitivity of the EISCAP biosensor. In addition, the capability of the multicell arrangement with multi-enzyme covered EISCAPs for sequentially detecting multianalytes (penicillin and urea) utilizing the enzymes penicillinase and urease has been experimentally demonstrated and discussed.
KW  - Field-effect biosensor
KW  - Capacitive model
KW  - Enzyme coverage
KW  - Multianalyte detection
KW  - Penicillin
Y1  - 2024
U6  - https://doi.org/10.1016/j.snb.2024.135530
SN  - 0925-4005 (Print)
SN  - 1873-3077 (Online)
N1  - Corresponding Author: Michael J. Schöning
VL  - 408
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Karschuck, Tobias
A1  - Kaulen, Corinna
A1  - Poghossian, Arshak
A1  - Wagner, Patrick H.
A1  - Schöning, Michael Josef
T1  - Gold nanoparticle-modified capacitive field-effect sensors: Studying the surface density of nanoparticles and coupling of charged polyelectrolyte macromolecules
JF  - Electrochemical Science Advances
N2  - The coupling of ligand-stabilized gold nanoparticles with field-effect devices offers new possibilities for label-free biosensing. In this work, we study the immobilization of aminooctanethiol-stabilized gold nanoparticles (AuAOTs) on the silicon dioxide surface of a capacitive field-effect sensor. The terminal amino group of the AuAOT is well suited for the functionalization with biomolecules. The attachment of the positively-charged AuAOTs on a capacitive field-effect sensor was detected by direct electrical readout using capacitance-voltage and constant capacitance measurements. With a higher particle density on the sensor surface, the measured signal change was correspondingly more pronounced. The results demonstrate the ability of capacitive field-effect sensors for the non-destructive quantitative validation of nanoparticle immobilization. In addition, the electrostatic binding of the polyanion polystyrene sulfonate to the AuAOT-modified sensor surface was studied as a model system for the label-free detection of charged macromolecules. Most likely, this approach can be transferred to the label-free detection of other charged molecules such as enzymes or antibodies.
KW  - polystyrene sulfonate
KW  - gold nanoparticles
KW  - field-effect sensor
KW  - detection of charged macromolecules
KW  - capacitive EIS sensor
Y1  - 2021
U6  - https://doi.org/10.1002/elsa.202100179
SN  - 0938-5193
VL  - 2
IS  - 5
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Karschuck, T. L.
A1  - Filipov, Y.
A1  - Bollella, P.
A1  - Schöning, Michael Josef
A1  - Katz, E.
T1  - Not-XOR (NXOR) logic gate based on an enzyme-catalyzed reaction
JF  - International Journal of Unconventional Computing
N2  - Enzyme-catalyzed reactions have been designed to mimic various Boolean logic gates in the general framework of unconventional biomolecular computing. While some of the logic gates, particularly OR, AND, are easy to realize with biocatalytic reactions and have been reported in numerous publications, some other, like NXOR, are very challenging and have not been realized yet with enzyme reactions. The paper reports on a novel approach to mimicking the NXOR logic gate using the bell-shaped enzyme activity dependent on pH values. Shifting pH from the optimum value to the acidic or basic values by using acid or base inputs (meaning 1,0 and 0,1 inputs) inhibits the enzyme reaction, while keeping the optimum pH (assuming 0,0 and 1,1 input combinations) preserves a high enzyme activity. The challenging part of the present approach is the selection of an enzyme with a well-demonstrated bell-shape activity dependence on the pH value. While many enzymes can satisfy this condition, we selected pyrroloquinoline quinone (PQQ)-dependent glucose dehydrogenase as this enzyme has the optimum pH center-located on the pH scale allowing the enzyme activity change by the acidic and basic pH shift from the optimum value corresponding to the highest activity. The present NXOR gate is added to the biomolecular “toolbox” as a new example of Boolean logic gates based on enzyme reactions.
Y1  - 2019
SN  - 1548-7199
VL  - 14
IS  - 3-4
SP  - 235
EP  - 242
PB  - Old City Publishing
CY  - Philadelphia
ER  - 
TY  - JOUR
A1  - Karnatak, Rajat
A1  - Kantz, Holger
A1  - Bialonski, Stephan
T1  - Early warning signal for interior crises in excitable systems
JF  - Physical Review E
Y1  - 2017
U6  - https://doi.org/10.1103/PhysRevE.96.042211
SN  - 2470-0053
VL  - 96
IS  - 4
SP  - 042211
ER  - 
TY  - JOUR
A1  - Karamanidis, Kiros
A1  - Albracht, Kirsten
A1  - Braunstein, Bjoern
A1  - Catala, Maria Moreno
A1  - Goldmann, Jan-Peter
A1  - Brüggemann, Gert-Peter
T1  - Lower leg musculoskeletal geometry and sprint performance
JF  - Gait and Posture
N2  - The purpose of this study was to investigate whether sprint performance is related to lower leg musculoskeletal geometry within a homogeneous group of highly trained 100-m sprinters. Using a cluster analysis, eighteen male sprinters were divided into two groups based on their personal best (fast: N = 11, 10.30 ± 0.07 s; slow: N = 7, 10.70 ± 0.08 s). Calf muscular fascicle arrangement and Achilles tendon moment arms (calculated by the gradient of tendon excursion versus ankle joint angle) were analyzed for each athlete using ultrasonography. Achilles tendon moment arm, foot and ankle skeletal geometry, fascicle arrangement as well as the ratio of fascicle length to Achilles tendon moment arm showed no significant (p > 0.05) correlation with sprint performance, nor were there any differences in the analyzed musculoskeletal parameters between the fast and slow sprinter group. Our findings provide evidence that differences in sprint ability in world-class athletes are not a result of differences in the geometrical design of the lower leg even when considering both skeletal and muscular components.
Y1  - 2011
U6  - https://doi.org/10.1016/j.gaitpost.2011.03.009
SN  - 0966-6362
VL  - 34
IS  - 1
SP  - 138
EP  - 141
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Kappmeyer, K.
A1  - Kotliar, Konstantin
A1  - Lanzl, I. M.
T1  - Spielen von Blasinstrumenten und Augeninnendruck
JF  - Zeitschrift für praktische Augenheilkunde & augenärztliche Fortbildung : ZPA
Y1  - 2009
SN  - 1436-0322
VL  - Bd. 30
SP  - 169
EP  - 171
ER  - 
TY  - JOUR
A1  - Kappler-Tanudyaya, Nathalie
A1  - Schmitt, Heike
A1  - Tippkötter, Nils
A1  - Meyer, Lina
A1  - Lenzen, Sigurd
A1  - Ulber, Roland
T1  - Combination of biotransformation and chromatography for the isolation and purification of mannoheptulose
JF  - Biotechnology Journal
N2  - Mannoheptulose is a seven-carbon sugar. It is an inhibitor of glucose-induced insulin secretion due to its ability to selectively inhibit the enzyme glucokinase. An improved procedure for mannoheptulose isolation from avocados is described in this study (based upon the original method by La Forge). The study focuses on the combination of biotransformation and downstream processing (preparative chromatography) as an efficient method to produce a pure extract of mannoheptulose. The experiments were divided into two major phases. In the first phase, several methods and parameters were compared to optimize the mannoheptulose extraction with respect to efficiency and purity. In the second phase, a mass balance of mannoheptulose over the whole extraction process was undertaken to estimate the yield and efficiency of the total extraction process. The combination of biotransformation and preparative chromatography allowed the production of a pure mannoheptulose extract. In a biological test, the sugar inhibited the glucokinase enzyme activity efficiently.
Y1  - 2007
U6  - https://doi.org/10.1002/biot.200700004
SN  - 1860-7314
VL  - 2
IS  - 6
SP  - 692
EP  - 699
ER  - 
TY  - JOUR
A1  - Kappler, Heinz
A1  - Form, Jürgen
T1  - Interaktive Computergraphik im Konstruktionsbuero. Einfuehrung und erste Erfahrungen mit CAD / Jürgen Form; Heinz Kappler
JF  - Heitkamp  Mitteilungen (1985)
Y1  - 1985
ER  - 
TY  - JOUR
A1  - Kapelyukh, Yury
A1  - Henderson, Colin James
A1  - Scheer, Nico
A1  - Rode, Anja
A1  - Wolf, Charles Roland
T1  - Defining the contribution of CYP1A1 and CYP1A2 to drug metabolism using humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 KO mice
JF  - Drug Metabolism and Disposition
Y1  - 2019
U6  - https://doi.org/10.1124/dmd.119.087718
IS  - Early view
ER  - 
TY  - JOUR
A1  - Kampker, Achim
A1  - Schleser, Markus
A1  - Triebs, Johannes
A1  - Berg, Alexander-Karl
A1  - Hansen, Jan Ole
A1  - Fiedler, Falko
T1  - Bauteilintegrierte Vorrichtungsfunktionen im Karosseriebau : Aktuelle Ergebnisse im Forschungsprojekt ProeK
JF  - ZWF Zeitschrift für wirtschaftlichen Fabrikbetrieb
N2  - Das Forschungsprojekt Produktionseffizienz in der Kleinserie (ProeK) erarbeitet kostengünstige und effiziente Lösungsansätze für Prozessketten im Zukunftsfeld der Elektromobilität. Das Teilprojekt Karosserie setzt diese Zielsetzung durch innovative und praxisorientierte Produkt- und Prozesskonzepte mit neuartigen bauteilintegrierten Vorrichtungsfunktionen (BiV) um. Im Teilprojekt Außenhaut sollen Toleranzen adaptiv durch Anpassungen der Prozessparameter sowie Bauteilmanipulation kompensiert werden.
Y1  - 2018
U6  - https://doi.org/10.3139/104.112012
SN  - 0947-0085
VL  - 113
IS  - 11
SP  - 767
EP  - 770
PB  - De Gruyter
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Kaminsky, Randolph
A1  - Weber, Hans-Joachim
A1  - Simons, Antoine
A1  - Kallweit, Stephan
A1  - Kramm, K.
A1  - Verdonck, Pascale
T1  - Comparison of the flow downstream two prototypes of a new monoleaflet artificial aortic heart valve by means of PIV visualization
JF  - Computer methods in biomechanics and biomedical engineering. 8 (2005), H. 4, Suppl. 1
Y1  - 2005
SN  - 1476-8259
SP  - 159
EP  - 160
ER  - 
TY  - JOUR
A1  - Kaminsky, Randolph
A1  - Simons, Antoine
A1  - Gatzweiler, Karl-Heinz
A1  - Weber, Hans-Joachim
T1  - Flow visualization by means of PIV of an artificial aortic heart valve fixed into a mock aorta
JF  - Acta Mechanica Slovaka 2-A. 9 (2005)
Y1  - 2005
SP  - 343
EP  - 348
ER  - 
TY  - JOUR
A1  - Kaminsky, Radoslav
A1  - Kallweit, Stephan
A1  - Weber, Hans-Joachim
A1  - Simons, Antoine
A1  - Kramm, K.
A1  - Jazwik, K.
A1  - Moll, J.
A1  - Verdonck, P.
T1  - 3D high speed piv assessment of a new aortic heart valve prototype
JF  - Journal of biomechanics. 39 (2006), H. Supplement 1
Y1  - 2006
SN  - 0021-9290
N1  - World Congress of Biomechanics <5, 2006, München>: Abstracts of the 5th World Congress of Biomechanics
SP  - S304
EP  - S305
PB  - -
ER  - 
TY  - JOUR
A1  - Kaminsky, Radoslav
A1  - Kallweit, Stephan
A1  - Weber, Hans-Joachim
A1  - Claessens, Tom
A1  - Jozwik, Krzystof
A1  - Verdonck, Pascal
T1  - Flow visualization through two types of aortic prosthetic heart valves using stereoscopic high-speed particle image velocimetry
JF  - Artificial organs. 31 (2007), H. 12
Y1  - 2007
SN  - 1525-1594
SP  - 869
EP  - 879
ER  - 
TY  - JOUR
A1  - Kaminsky, Radoslav
A1  - Dumont, K.
A1  - Weber, Hans-Joachim
A1  - Schroll, M.
A1  - Verdonck, P.
T1  - PIV validation of blood-heart valve leaflet interaction modelling
JF  - The International journal of artificial organs. 30 (2007), H. 7
Y1  - 2007
SP  - 640
EP  - 648
PB  - -
ER  - 
TY  - JOUR
A1  - Kaltschmitt, Martin
A1  - Thrän, Daniela
A1  - Fredebeul-Krein, Markus
A1  - Vogel, Erika
A1  - Kalitzky, Thomas
A1  - Ehrhart, Karl Martin
A1  - Hoppe, Christian
A1  - Seifert, Stefan
A1  - Sijm, Jos
A1  - Böhringer, Christoph
A1  - Hoffmann, Tim
A1  - Moslener, Ulf
A1  - Sturm, Bodo
A1  - Diekmann, Jochen
A1  - Schleich, Joachim
T1  - CO2-Emissionshandel
JF  - Zeitschrift für Energiewirtschaft
Y1  - 2006
SN  - 0343-5377 (Print) 1866-2765 (Online)
VL  - Vol. 30
IS  - Iss. 4
SP  - 271
EP  - 314
ER  - 
TY  - JOUR
A1  - Kallweit, Stephan
A1  - Willert, Chris
A1  - Dues, Michael
A1  - Müller, Ulrich
T1  - PIV for Volume Flow Metering / Kallweit, Stephan ; Willert, Chris ; Dues, Michael ; Müller, Ulrich ; Lederer, Thomas
Y1  - 2008
N1  - 14th International Symposium on Applications of Laser Techniques to Fluid Mechanics, 2008-07-07 - 2008-07-10, Lisbon (Portugal)
SP  - 6 S.
ER  -