TY - JOUR A1 - Kallweit, Stephan A1 - Kaminsky, R. A1 - Rossi, M. A1 - Morbiducci, U. T1 - 2D PIV Study of the flow downstream : Two prototypes of a ney monoleaflet artificial aortic heart valve prosthesis / Kaminsky, R. ; Kramm, K. ; Weber, H. J. ; Simons, A. P. ; Kallweit, S. ; Verdonck, P. R. JF - The International Journal of Artificial Organs. 28 (2005), H. 9 Y1 - 2005 SN - 1724-6040 N1 - Abstracts: XXXII Annual ESAO Congress, 5-8 October 2005, Bologna - Italy SP - 921 ER - TY - JOUR A1 - Kallweit, Stephan A1 - Kaminsky, R. A1 - Rossi, M. A1 - Morbiducci, U. T1 - 3D PIV measurements of prosthetic heart valve dynamics / Kaminsky, R. ; Rossi, M. ; Morbiducci, U. ; Scalise, L. ; Castellini, P. ; Kallweit, S. ; Verdonck, P. ; Grigioni, M. JF - The International Journal of Artificial Organs. 28 (2005), H. 9 Y1 - 2005 SN - 1724-6040 N1 - Abstracts: XXXII Annual ESAO Congress, 5-8 October 2005, Bologna - Italy SP - 868 ER - TY - JOUR A1 - Kallweit, Stephan A1 - Kaminsky, R. A1 - Canneyt, C. van A1 - Eloot, S. T1 - High-Speed und Stereo-PIV in einem künstlichen Blutgefäß / Kallweit, S. ; Kaminsky, R. ; Canneyt, C. van ; Eloot, S. JF - Lasermethoden in der Strömungsmesstechnik: 15. Fachtagung 2007 Rostock / Hrsg.: Alfred Leder .... Y1 - 2007 SN - 978-3-86009-007-7 N1 - Deutsche Gesellschaft für Laser-Anemometrie ; Fachtagung Lasermethoden in der Strömungsmesstechnik <15, 2007, Rostock> SP - 48 ER - TY - JOUR A1 - Kallweit, Stephan A1 - Helbing, M. A1 - Orglmeister, R. A1 - Siekmann, H. E. T1 - Image Processing Techniques with Neural Networks for Flow Visualization in Rotating Machinery / Helbing, M. ; Orgimeiste, R. [Orglmeister, R.] ; Kallweit, S. ; Siekmann, H. E. ; Dues, M. ; Cronemeyer, J. JF - FLUCOME '94 : the 4th Triennial International Symposium on Fluid Control, Measurement and Visualization; August 29 - September 1, 1994, Toulouse, France, International Congress Centre, DIGORA-Labège / CERT/ONERA. General chairman Patrick Hebrard Y1 - 1994 SP - 87 EP - 94 CY - Toulouse ER - TY - JOUR A1 - Kallweit, Stephan A1 - Ebinger, G. A1 - Dues, M. A1 - Siekmann, H. T1 - Anwendung des Laserlichtschnitt-Verfahrens zur qualitativen Untersuchung der Durchströmung von Kreiselpumpen / Ebinger, G. ; Kallweit, S. ; Dues, M. ; Siekmann, H. JF - Lasermethoden in der Strömungsmesstechnik, 2. Fachtagung der Deutschen Gesellschaft für Laser-Anemometrie (GALA), PTB Braunschweig, DE, 14.-16. Sep, 1993 Y1 - 1993 SN - 3-86111-595-6 N1 - Lasermethoden in der Strömungsmesstechnik, Fachtagung, 2 SP - 37.1 EP - 37.4 PB - Shaker CY - Aachen ER - TY - JOUR A1 - Kallweit, Stephan A1 - Dues, Michael A1 - Radke, Michael T1 - Möglichkeiten und Grenzen laseroptischer Verfahren zur Untersuchung hydraulischer Strömungsmaschinen / Dues, Michael ; Kallweit, Stephan ; Radke, Michael JF - Forschung im Ingenieurwesen. 60 (1994), H. 11-12 Y1 - 1994 SN - 0015-7899 SP - 332 EP - 336 ER - TY - JOUR A1 - Kallweit, Stephan A1 - Dues, Michael A1 - Müller, Ulli A1 - Lederer, Thomas T1 - Einsatz der Particle Image Velocimetry zur Untersuchung von Rohrströmungen / Kallweit, Stephan ; Dues, Michael ; Müller, Ulli ; Lederer, Thomas ; Schroll, Michael ; Willert, Christian JF - Lasermethoden in der Strömungsmesstechnik: 15. Fachtagung 2007 Rostock / Hrsg.: Alfred Leder .... Y1 - 2007 SN - 978-3-86009-007-7 N1 - Deutsche Gesellschaft für Laser-Anemometrie ; Fachtagung Lasermethoden in der Strömungsmesstechnik <15, 2007, Rostock> SP - 35 ER - TY - JOUR A1 - Kallweit, Stephan A1 - Dues, M. W. A1 - Siekmann, H. E. T1 - Spectral Analysis of Pressure Fluctuations and Velocity Fields as Investigated on Propeller Pumps / Dues, M. W. ; Kallweit, S. D. ; Siekmann, H. E. JF - Preprints : Fifth International Symposium on Transport Phenomena and Dynamics of Rotating Machinery (ISROMAC-5) : May 8 - 11, 1994, Maui Marriott Hotel, Kaanapali, Maui, Hawaii, U.S.A / sponsored by Pacific Center of Thermal-Fluids Engineering. [W.-J. Yang, chairman] / Vol. B. Y1 - 1994 N1 - International Symposium on Transport Phenomena and Dynamics of Rotating Machinery 5, 1994, Kaanapali, Hawaii SP - 98 EP - 112 ER - TY - JOUR A1 - Kallweit, Stephan A1 - Dues, M. A1 - Siekmann, H. T1 - Particle-Image-Velocimetry (PIV) in rotierenden Maschinen / Dues, M. ; Kallweit, S. ; Siekmann, H. JF - Lasermethoden in der Strömungsmesstechnik, 3. Fachtagung der Deutschen Gesellschaft für Laser-Anemometrie (GALA), Bremen, DE, 5.-7. Sep, 1994 Y1 - 1994 SN - 3-8265-0162-4 N1 - Lasermethoden in der Strömungsmesstechnik, Fachtagung, 3 SP - 19.1 EP - 19-5 PB - Shaker CY - Aachen ER - TY - JOUR A1 - Kallweit, Stephan A1 - Abromeit, W. A1 - Dues, M. A1 - Siekmann, H. T1 - Anwendung der LDA zur Untersuchung der instationären Strömung im Nachleitrad einer axialen Kreiselpumpenstufe / Abromeit, W. ; Dues, M. ; Siekmann, H. ; Kallweit, S. JF - Lasermethoden in der Strömungsmesstechnik, 3. Fachtagung der Deutschen Gesellschaft für Laser-Anemometrie (GALA), Bremen, DE, 5.-7. Sep, 1994 Y1 - 1994 SN - 3-8265-0162-4 N1 - Lasermethoden in der Strömungsmesstechnik, Fachtagung, 3 SP - 27.1 EP - 27.6 PB - Shaker CY - Aachen ER - TY - JOUR A1 - Kalbe, Jochen A1 - Kuropka, Rolf A1 - Meyer-Stork, L. Sebastian A1 - Berndt, Heinz A1 - Sauter, Sybille L. A1 - Loss, Peter A1 - Hendo, Karsten A1 - Riesner, Detlev A1 - Höcker, Hartwig T1 - Isolation and characterization of high-molecular mass DNA from hair shafts JF - Biological chemistry Y1 - 1988 SN - 0177-3593 U6 - https://doi.org/10.1515/bchm3.1988.369.1.413 VL - 369 IS - 1 SP - 413 EP - 416 ER - TY - JOUR A1 - Kalbe, Jochen A1 - Höcker, Hartwig A1 - Berndt, Heinz T1 - Design of enzyme reactors as chromatographic columns for racemic resolution of amino acid esters JF - Chromatographia Y1 - 1989 SN - 0009-5893 U6 - https://doi.org/10.1007/BF02319646 VL - 28 IS - 3-4 SP - 193 EP - 196 ER - TY - JOUR A1 - Kahmann, Stephanie L. A1 - Rausch, Valentin A1 - Plümer, Jonathan A1 - Müller, Lars P. A1 - Pieper, Martin A1 - Wegmann, Kilian T1 - The automized fracture edge detection and generation of three-dimensional fracture probability heat maps JF - Medical Engineering & Physics N2 - With proven impact of statistical fracture analysis on fracture classifications, it is desirable to minimize the manual work and to maximize repeatability of this approach. We address this with an algorithm that reduces the manual effort to segmentation, fragment identification and reduction. The fracture edge detection and heat map generation are performed automatically. With the same input, the algorithm always delivers the same output. The tool transforms one intact template consecutively onto each fractured specimen by linear least square optimization, detects the fragment edges in the template and then superimposes them to generate a fracture probability heat map. We hypothesized that the algorithm runs faster than the manual evaluation and with low (< 5 mm) deviation. We tested the hypothesis in 10 fractured proximal humeri and found that it performs with good accuracy (2.5 mm ± 2.4 mm averaged Euclidean distance) and speed (23 times faster). When applied to a distal humerus, a tibia plateau, and a scaphoid fracture, the run times were low (1–2 min), and the detected edges correct by visual judgement. In the geometrically complex acetabulum, at a run time of 78 min some outliers were considered acceptable. An automatically generated fracture probability heat map based on 50 proximal humerus fractures matches the areas of high risk of fracture reported in medical literature. Such automation of the fracture analysis method is advantageous and could be extended to reduce the manual effort even further. KW - Fracture classification KW - Shoulder KW - Probability distribution mapping KW - Morphing KW - Imaging Y1 - 2022 SN - 1350-4533 VL - 2022 IS - 110 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Jörissen, Jörg A1 - Heger, Michael T1 - Zur Wirkung hochschuldidaktisch fundierter und in den Fachbereichen verankerter Lehrveranstaltungsevaluation JF - Qualität in der Wissenschaft (QiW) Y1 - 2014 SN - 1860-3041 VL - 8 IS - 2+3 SP - 70 EP - 80 PB - Universitätsverlag Webler CY - Bielefeld ER - TY - JOUR A1 - Jungbluth, Christian A1 - Borchert, Jörg T1 - Möglichkeiten der Strompreisbeeinflussung im oligopolistischen Markt JF - ZNER Zeitschrift für Neues Energierecht Y1 - 2008 IS - 4 SP - 314 EP - 323 ER - TY - JOUR A1 - Jung, Alexander A1 - Staat, Manfred A1 - Müller, Wolfram T1 - Corrigendum to “Flight style optimization in ski jumping on normal, large, and ski flying hills” [J. Biomech 47 (2014) 716–722] JF - Journals of Biomechanics Y1 - 2018 U6 - https://doi.org/10.1016/j.jbiomech.2018.02.001 SN - 0021-9290 N1 - refers to Journal of Biomechanics Vol 47, Issue 3, Pages 716-722: https://doi.org/10.1016/j.jbiomech.2013.11.021 SP - 313 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Jung, Alexander A1 - Staat, Manfred A1 - Müller, Wolfram T1 - Flight style optimization in ski jumping on normal, large, and ski flying hills JF - Journal of biomechanics Y1 - 2013 SN - 1873-2380 (E-Journal); 0021-9290 (Print) N1 - Corrigendum to “Flight style optimization in ski jumping on normal, large, and ski flying hills” [J. Biomech 47 (2014) 716-722] Journal of Biomechanics, 2018;71:313. VL - Vol. 47 IS - Iss. 3 SP - 716 EP - 722 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Jung, Alexander A1 - Staat, Manfred T1 - Erratum to "Modeling and simulation of human induced pluripotent stem cell-derived cardiac tissue" [GAMM-Mitteilungen, (2019), 42, 4, 10.1002/gamm.201900002] JF - GAMM-Mitteilungen Y1 - 2020 U6 - https://doi.org/10.1002/gamm.202000011 SN - 1522-2608 N1 - Refers to: Modeling and simulation of human induced pluripotent stem cell-derived cardiac tissue. Alexander Jung, Manfred Staat. Volume 42, Issue 4. GAMM-Mitteilungen, 2019. https://doi.org/10.1002/gamm.201900002 VL - 43 IS - 4 PB - Wiley-VCH GmbH CY - Weinheim ER - TY - JOUR A1 - Jung, Alexander A1 - Staat, Manfred T1 - Modeling and simulation of human induced pluripotent stem cell-derived cardiac tissue JF - GAMM - Mitteilungen der Gesellschaft für Angewandte Mathematik und Mechanik Y1 - 2019 U6 - https://doi.org/10.1002/gamm.201900002 SN - 1522-2608 VL - 42 IS - 4 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Jung, Alexander A1 - Müller, Wolfram A1 - Staat, Manfred T1 - Wind and fairness in ski jumping: A computer modelling analysis JF - Journal of Biomechanics N2 - Wind is closely associated with the discussion of fairness in ski jumping. To counter-act its influence on the jump length, the International Ski Federation (FIS) has introduced a wind compensation approach. We applied three differently accurate computer models of the flight phase with wind (M1, M2, and M3) to study the jump length effects of various wind scenarios. The previously used model M1 is accurate for wind blowing in direction of the flight path, but inaccuracies are to be expected for wind directions deviating from the tangent to the flight path. M2 considers the change of airflow direction, but it does not consider the associated change in the angle of attack of the skis which additionally modifies drag and lift area time functions. M3 predicts the length effect for all wind directions within the plane of the flight trajectory without any mathematical simplification. Prediction errors of M3 are determined only by the quality of the input data: wind velocity, drag and lift area functions, take-off velocity, and weight. For comparing the three models, drag and lift area functions of an optimized reference jump were used. Results obtained with M2, which is much easier to handle than M3, did not deviate noticeably when compared to predictions of the reference model M3. Therefore, we suggest to use M2 in future applications. A comparison of M2 predictions with the FIS wind compensation system showed substantial discrepancies, for instance: in the first flight phase, tailwind can increase jump length, and headwind can decrease it; this is opposite of what had been anticipated before and is not considered in the current wind compensation system in ski jumping. Y1 - 2018 U6 - https://doi.org/10.1016/j.jbiomech.2018.05.001 SN - 0021-9290 IS - 75 SP - 147 EP - 153 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Jung, Alexander A1 - Müller, Wolfram A1 - Staat, Manfred T1 - Optimization of the flight technique in ski jumping: the influence of wind Y1 - 2019 U6 - https://doi.org/10.1016/j.jbiomech.2019.03.023 IS - Early view PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Jossek, Ralf A1 - Bongaerts, Johannes A1 - Sprenger, Georg A. T1 - Characterization of a new feedback-resistant 3-deoxy-D-arabinoheptulosonate 7-phosphate synthase AroF of Escherichia coli JF - FEMS microbiology letters Y1 - 2001 SN - 1574-6968 VL - Vol. 202 IS - Iss. 1 SP - 145 EP - 148 ER - TY - JOUR A1 - Jordan, Sabine D. A1 - Krüger, Markus A1 - Willmes, Diana M. A1 - Redemann, Nora A1 - Wunderlich, F. Thomas A1 - Brönneke, Hella S. A1 - Merkwirth, Carsten A1 - Kashkar, Hamid A1 - Olkkonen, Vesa M. A1 - Böttger, Thomas A1 - Braun, Thomas A1 - Seibler, Jost A1 - Brüning, Jens C. T1 - Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism JF - Nature Cell Biology N2 - The contribution of altered post-transcriptional gene silencing to the development of insulin resistance and type 2 diabetes mellitus so far remains elusive. Here, we demonstrate that expression of microRNA (miR)-143 and 145 is upregulated in the liver of genetic and dietary mouse models of obesity. Induced transgenic overexpression of miR-143, but not miR-145, impairs insulin-stimulated AKT activation and glucose homeostasis. Conversely, mice deficient for the miR-143–145 cluster are protected from the development of obesity-associated insulin resistance. Quantitative-mass-spectrometry-based analysis of hepatic protein expression in miR-143-overexpressing mice revealed miR-143-dependent downregulation of oxysterol-binding-protein-related protein (ORP) 8. Reduced ORP8 expression in cultured liver cells impairs the ability of insulin to induce AKT activation, revealing an ORP8-dependent mechanism of AKT regulation. Our experiments provide direct evidence that dysregulated post-transcriptional gene silencing contributes to the development of obesity-induced insulin resistance, and characterize the miR-143–ORP8 pathway as a potential target for the treatment of obesity-associated diabetes. Y1 - 2011 U6 - https://doi.org/10.1038/ncb2211 SN - 1465-7392 VL - 13 IS - 4 SP - 434 EP - 446 PB - Nature CY - New York ER - TY - JOUR A1 - Jochim, Haldor E. A1 - Menzel, Christoph J. T1 - Die Trassenbündelung als Planungsmethode nachhaltiger Verkehrspolitik JF - Der Eisenbahningenieur : EI Y1 - 2018 SN - 0013-2810 VL - 69 IS - 11 SP - 26 EP - 31 PB - DVV Media Group CY - Hamburg ER - TY - JOUR A1 - Jochim, Haldor E. A1 - Menzel, Christoph T1 - Ist der Bachelor des Diplom-Ingenieurs Untergang? Chancen, Risiken und Perspektiven des neuen Studiensystems JF - EI - Eisenbahningenieur. 57 (2006), H. 7 Y1 - 2006 SN - 0013-2810 SP - 52 EP - 56 ER - TY - JOUR A1 - Jochim, Haldor E. T1 - Verkehrswirtschaftliche Ermittlung von Qualitätsmaßstäben im Eisenbahnbetrieb JF - Der Eisenbahningenieur : Elektronische Ressource : EI / Verband Deutscher Eisenbahn-Ingenieure e.V. (VDEI). 51 (2000), H. 7 Y1 - 2000 SN - 0013-2810 SP - 5 EP - 8 ER - TY - JOUR A1 - Jochim, Haldor E. T1 - Verspätungsbewertung im Schienenpersonenfernverkehr in Deutschland JF - Doprava a kvalita II : zborník = Verkehr und Qualität II / 4. Medzinárodné Vedecké Dopravné Kolokvium EIPOS, Žilina, 19. - 21.9.1996. Európsky Inštitút pre Postgraduálne Vzdelávanie TU Drážďany ... [Zost. František Schlosser] Y1 - 1996 N1 - Internationales Kolloquium Verkehrswissenschaften ; (4, 1996, Žilina) ; Europäisches Institut für Postgraduale Bildung an der TU Dresden PB - Vysoká Škola Dopravy a Spojov CY - Žilina ER - TY - JOUR A1 - Jochim, Haldor E. T1 - Verkehrswirtschaftliche Ermittlung von Qualitätsmaßstäben im Eisenbahnbetrieb JF - Eisenbahntechnische Rundschau : ETR ; Zeitschrift für die gesamte Eisenbahntechnik. 49 (2000), H. 6 Y1 - 2000 ER - TY - JOUR A1 - Jochim, Haldor E. T1 - Die Kapazität von Engpassstrecken der Eisenbahn bei der Trennung von Netz und Betrieb JF - Verkehrswissenschaftliche Tage der Hochschule für Verkehrswesen "Friedrich List" in Dresden / Technische Universität Dresden, Fakultät Verkehrswissenschaften Y1 - 2001 N1 - 18. Verkehrswissenschaftliche Tage Dresden, 17. September 2001 ER - TY - JOUR A1 - Jochim, Haldor E. T1 - Wieviel dürfen Verspätungsgarantien kosten? JF - Verkehrswissenschaftliche Tage der Hochschule für Verkehrswesen "Friedrich List" in Dresden / Technische Universität Dresden, Fakultät Verkehrswissenschaften Y1 - 2003 N1 - 19. Verkehrswissenschaftliche Tage Dresden, 22. September 2003 ER - TY - JOUR A1 - Jochim, Haldor E. T1 - Charging rail operators for delays – how not to do it JF - Networks for mobility : International Symposium, September 18 - 20, 2002, Stuttgart, Germany ; proceedings / University of Stuttgart, Centre of Transporation Research (FOVUS). W. Möhlenbrink ... (eds.) Y1 - 2002 SN - 3893010858 N1 - International Symposium ; (2002.09.18-20 : ; Stuttgart) PB - FOVUS CY - Stuttgart ER - TY - JOUR A1 - Jochim, Haldor E. T1 - A traffic resistance model of long-distance travel JF - Networks for mobility : 2nd international symposium, September 29 - October 1, 2004, Stuttgart, Germany ; proceedings ; abstracts and CD-ROM / [2nd International Symposium on Networks for Mobility]. FOVUS, Centre of Transportation Research, University of Y1 - 2004 SN - 3-89301-180-3 N1 - International Symposium on Networks for Mobility (2, 2004, Stuttgart) PB - FOVUS CY - Stuttgart ER - TY - JOUR A1 - Jochim, Haldor E. T1 - Warum Ingenieure nicht rechnen und Controller nicht schätzen können JF - EI - Eisenbahningenieur. 57 (2006), H. 1 Y1 - 2006 SN - 0013-2810 SP - 54 EP - 56 ER - TY - JOUR A1 - Jochim, Haldor E. T1 - Verspätungen auf Stammstrecken - wie man sie (nicht) in den Griff bekommt JF - Der Nahverkehr. 23 (2005), H. 6 Y1 - 2005 SN - 0722-8287 ER - TY - JOUR A1 - Jochim, Haldor E. T1 - Verspätungsentschädigungen der Bahnen. Verkehrswirtschaftliche Anmerkungen zum Regierungsgutachten "Verbraucherschutz und Kundenrechte im öffentlichen Personenverkehr". JF - Internationales Verkehrswesen. 59 (2007), H. 3 Y1 - 2007 SN - 0020-9511 N1 - ab 09/2007 frei zugänglich SP - 95 EP - 99 ER - TY - JOUR A1 - Jochim, Haldor E. T1 - Die Ostheidebahn - eine Alternative zur Y-Trasse JF - ETR - Eisenbahntechnische Rundschau Y1 - 2012 SN - 0013-2845 VL - 61 IS - 11 SP - 34 EP - 37 PB - DVV Media Group CY - Hamburg ER - TY - JOUR A1 - Jochim, Haldor E. T1 - Beurteilung der Ausbaunotwendigkeit von Eisenbahn-Streckenabschnitten - ein anspruchsloses Verfahren JF - Eisenbahn-Ingenieur-Kalender 2008 : EIK ; Jahrbuch für Schienenverkehr & Technik / Hrsg. Verband Deutscher Eisenbahn-Ingenieure e.V., VDEI Y1 - 2007 SN - 0934-5930 SP - 333 EP - 342 ER - TY - JOUR A1 - Jiminez German, Salvador A1 - Behbahani, Mehdi A1 - Miettinen, Susanna A1 - Grijpma, Dirk W. A1 - Haimi, Suvi P. T1 - Proliferation and differentiation of adipose stem cells towards smooth muscle cells on poly(trimethylene carbonate) membranes JF - Macromolecular symposia Y1 - 2013 SN - 0258-0322 VL - Vol. 334 IS - Iss. 1 SP - 133 EP - 142 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Jildeh, Zaid B. A1 - Wagner, Torsten A1 - Schöning, Michael Josef A1 - Pieper, Martin T1 - Simulating the electromagnetic‐thermal treatment of thin aluminium layers for adhesion improvement JF - Physica status solidi (a) N2 - A composite layer material used in packaging industry is made from joining layers of different materials using an adhesive. An important processing step in the production of aluminium-containing composites is the surface treatment and consequent coating of adhesive material on the aluminium surface. To increase adhesion strength between aluminium layer and the adhesive material, the foil is heat treated. For efficient heating, induction heating was considered as state-of-the-art treatment process. Due to the complexity of the heating process and the unpredictable nature of the heating source, the control of the process is not yet optimised. In this work, a finite element analysis of the process was established and various process parameters were studied. The process was simplified and modelled in 3D. The numerical model contains an air domain, an aluminium layer and a copper coil fitted with a magnetic field concentrating material. The effect of changing the speed of the aluminium foil (or rolling speed) was studied with the change of the coil current. Statistical analysis was used for generating a general control equation of coil current with changing rolling speed. Y1 - 2015 U6 - https://doi.org/10.1002/pssa.201431893 SN - 1862-6319 VL - Vol. 212 IS - 6 SP - 1234 EP - 1241 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Jildeh, Zaid B. A1 - Oberländer, Jan A1 - Kirchner, Patrick A1 - Wagner, Patrick H. A1 - Schöning, Michael Josef T1 - Thermocatalytic Behavior of Manganese (IV) Oxide as Nanoporous Material on the Dissociation of a Gas Mixture Containing Hydrogen Peroxide JF - Nanomaterials N2 - In this article, we present an overview on the thermocatalytic reaction of hydrogen peroxide (H₂O₂) gas on a manganese (IV) oxide (MnO₂) catalytic structure. The principle of operation and manufacturing techniques are introduced for a calorimetric H₂O₂ gas sensor based on porous MnO₂. Results from surface analyses by X-ray photoelectron spectroscopy (XPS) and scanning electron microscopy (SEM) of the catalytic material provide indication of the H₂O₂ dissociation reaction schemes. The correlation between theory and the experiments is documented in numerical models of the catalytic reaction. The aim of the numerical models is to provide further information on the reaction kinetics and performance enhancement of the porous MnO₂ catalyst. Y1 - 2018 U6 - https://doi.org/10.3390/nano8040262 SN - 2079-4991 VL - 8 IS - 4 PB - MDPI CY - Basel ER - TY - JOUR A1 - Jildeh, Zaid B. A1 - Oberländer, Jan A1 - Kirchner, Patrick A1 - Keusgen, Michael A1 - Wagner, Patrick H. A1 - Schöning, Michael Josef T1 - Experimental and Numerical Analyzes of a Sensor Based on Interdigitated Electrodes for Studying Microbiological Alterations JF - physica status solidi (a): applications and materials science N2 - In this work, a cell-based biosensor to evaluate the sterilization efficacy of hydrogen peroxide vapor sterilization processes is characterized. The transducer of the biosensor is based on interdigitated gold electrodes fabricated on an inert glass substrate. Impedance spectroscopy is applied to evaluate the sensor behavior and the alteration of test microorganisms due to the sterilization process. These alterations are related to changes in relative permittivity and electrical conductivity of the bacterial spores. Sensor measurements are conducted with and without bacterial spores (Bacillus atrophaeus), as well as after an industrial sterilization protocol. Equivalent two-dimensional numerical models based on finite element method of the periodic finger structures of the interdigitated gold electrodes are designed and validated using COMSOL® Multiphysics software by the application of known dielectric properties. The validated models are used to compute the electrical properties at different sensor states (blank, loaded with spores, and after sterilization). As a final result, we will derive and tabulate the frequency-dependent electrical parameters of the spore layer using a novel model that combines experimental data with numerical optimization techniques. Y1 - 2018 U6 - https://doi.org/10.1002/pssa.201700920 SN - 1862-6319 VL - 215 IS - 15 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Jildeh, Zaid B. A1 - Kirchner, Patrick A1 - Oberländer, Jan A1 - Vahidpour, Farnoosh A1 - Wagner, Patrick H. A1 - Schöning, Michael Josef T1 - Development of a package-sterilization process for aseptic filling machines: A numerical approach and validation for surface treatment with hydrogen peroxide JF - Sensor and Actuators A: Physical N2 - Within the present work a sterilization process by a heated gas mixture that contains hydrogen peroxide (H₂O₂) is validated by experiments and numerical modeling techniques. The operational parameters that affect the sterilization efficacy are described alongside the two modes of sterilization: gaseous and condensed H₂O₂. Measurements with a previously developed H₂O₂ gas sensor are carried out to validate the applied H₂O₂ gas concentration during sterilization. We performed microbiological tests at different H₂O₂ gas concentrations by applying an end-point method to carrier strips, which contain different inoculation loads of Geobacillus stearothermophilus spores. The analysis of the sterilization process of a pharmaceutical glass vial is performed by numerical modeling. The numerical model combines heat- and advection-diffusion mass transfer with vapor–pressure equations to predict the location of condensate formation and the concentration of H₂O₂ at the packaging surfaces by changing the gas temperature. For a sterilization process of 0.7 s, a H₂O₂ gas concentration above 4% v/v is required to reach a log-count reduction above six. The numerical results showed the location of H₂O₂ condensate formation, which decreases with increasing sterilant-gas temperature. The model can be transferred to different gas nozzle- and packaging geometries to assure the absence of H₂O₂ residues. Y1 - 2020 U6 - https://doi.org/10.1016/j.sna.2019.111691 SN - 0924-4247 VL - 303 IS - 111691 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Jildeh, Zaid B. A1 - Kirchner, Patrick A1 - Oberländer, Jan A1 - Kremers, Alexander A1 - Wagner, Torsten A1 - Wagner, Patrick H. A1 - Schöning, Michael Josef T1 - FEM-based modeling of a calorimetric gas sensor for hydrogen peroxide monitoring JF - physica status solidi a : applications and materials sciences N2 - A physically coupled finite element method (FEM) model is developed to study the response behavior of a calorimetric gas sensor. The modeled sensor serves as a monitoring device of the concentration of gaseous hydrogen peroxide (H2 O2) in a high temperature mixture stream in aseptic sterilization processes. The principle of operation of a calorimetric H2 O2 sensor is analyzed and the results of the numerical model have been validated by using previously published sensor experiments. The deviation in the results between the FEM model and experimental data are presented and discussed. Y1 - 2017 U6 - https://doi.org/10.1002/pssa.201600912 SN - 1862-6319 IS - Early View PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Jildeh, Zaid B. A1 - Kirchner, Patrick A1 - Baltes, Klaus A1 - Wagner, Patrick H. A1 - Schöning, Michael Josef T1 - Development of an in-line evaporation unit for the production of gas mixtures containing hydrogen peroxide – numerical modeling and experimental results JF - International Journal of Heat and Mass Transfer N2 - Hydrogen peroxide (H2O2) is a typical surface sterilization agent for packaging materials used in the pharmaceutical, food and beverage industries. We use the finite-elements method to analyze the conceptual design of an in-line thermal evaporation unit to produce a heated gas mixture of air and evaporated H2O2 solution. For the numerical model, the required phase-transition variables of pure H2O2 solution and of the aerosol mixture are acquired from vapor-liquid equilibrium (VLE) diagrams derived from vapor-pressure formulations. This work combines homogeneous single-phase turbulent flow with heat-transfer physics to describe the operation of the evaporation unit. We introduce the apparent heat-capacity concept to approximate the non-isothermal phase-transition process of the H2O2-containing aerosol. Empirical and analytical functions are defined to represent the temperature- and pressure-dependent material properties of the aqueous H2O2 solution, the aerosol and the gas mixture. To validate the numerical model, the simulation results are compared to experimental data on the heating power required to produce the gas mixture. This shows good agreement with the deviations below 10%. Experimental observations on the formation of deposits due to the evaporation of stabilized H2O2 solution fits the prediction made from simulation results. Y1 - 2019 U6 - https://doi.org/10.1016/j.ijheatmasstransfer.2019.118519 SN - 0017-9310 VL - 143 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Jeromin, Günter Erich A1 - Zoor, Annegreth T1 - A new irreversible enzyme-aided esterification method in organic solvents JF - Biotechnology letters. 30 (2008), H. 5 Y1 - 2008 SN - 1573-6776 SP - 925 EP - 928 ER - TY - JOUR A1 - Jeromin, Günter Erich A1 - Welsch, Volker T1 - Diketene a New Esterification Reagent in the Enzyme-Aided Synthesis of Chiral Alcohols and Chiral Acetoacetic Acid Esters JF - Tetrahedron Letters . 36 (1995), H. 37 Y1 - 1995 SN - 0040-4039 N1 - ISSN der E-Ausg.: 1359-8562 SP - 6663 EP - 6664 ER - TY - JOUR A1 - Jeromin, Günter Erich A1 - Weise, Sven T1 - Enzymatische Acetylierung von (±)-1-Phthalimido-2-propanol JF - Liebigs Annalen der Chemie (1990) Y1 - 1990 SN - 0947-3440 N1 - ISSN der E-Ausg.: 1099-0690 SP - 1045 EP - 1046 ER - TY - JOUR A1 - Jeromin, Günter Erich A1 - Scheidt, Annette T1 - Aliphatic optically active alcohols by enzyme-aided synthesis JF - Tetrahedron Letters . 32 (1991), H. 48 Y1 - 1991 SN - 0040-4039 N1 - ISSN der E-Ausg.: 1359-8562 SP - 7021 EP - 7024 ER - TY - JOUR A1 - Jeromin, Günter Erich A1 - Albertz, Michael T1 - Optically active α-acetoxycarboxylic acids and α-hydroxycarboxylic acids by enzyme-aided syntheses JF - Journal für Praktische Chemie / Chemiker-Zeitung. 334 (1992), H. 6 Y1 - 1992 SN - 1436-9966 N1 - ISSN der E-Ausg.: 1521-3897 ; In der Bibliothek (Jülich) vorhanden unter 63 ZS 024-1992 SP - 526 EP - 528 ER - TY - JOUR A1 - Jeromin, Günter Erich T1 - Superabsorbed alcohol dehydrogenase—a new catalyst for asymmetric reductions JF - Biotechnology Letters. 31 (2009), H. 11 Y1 - 2009 SN - 0141-5492 SP - 1717 EP - 1721 ER -