TY - JOUR A1 - Wolf, Martin R. A1 - Armbruster, S. A1 - Schlick, Christopher A1 - Simon, S. T1 - Marktübersicht Telekooperationssysteme - Das IAW stellt im Internet umfangreiche Informationen über Telekooperationssysteme zur Verfügung / Wolf, M. ; Armbruster, S. ; Schlick, C. ; Simon, S. JF - FIR + IAW Mitteilungen. 29 (1997), H. 1 Y1 - 1997 SP - 11 EP - 12 PB - - ER - TY - JOUR A1 - Wolf, Martin R. A1 - Armbruster, S. A1 - Schlick, Christopher A1 - Simon, S. T1 - Marktübersicht Telekooperationssysteme / Wolf, M.; Armbruster, S.; Schlick, C.; Simon, S. JF - Elsa Insight (1997) Y1 - 1997 SP - 8 EP - 9 PB - - ER - TY - JOUR A1 - Wolf, Martin R. A1 - Simon, S. A1 - Schlick, Christopher T1 - Computergestützte Kooperation - Eine Seifenblase? / Wolf, M.; Simon, S.; Schlick, C. JF - Rechnergestützte Kooperation in Verwaltungen und großen Unternehmen : Tagungsband zum Workshop der GI-Gachgruppe / Peter Mambrey ... ( Hrsg.) Y1 - 1997 SP - 220 EP - 234 PB - Univ., Fachbereich Mathematik u. Informatik CY - Essen ER - TY - JOUR A1 - Wolf, Martin R. A1 - Schlick, Christopher A1 - Springer, J. ED - Miyamoto, Hiroyuki T1 - The use of implicit communication mechanisms in desktop-teleconferencing-systems JF - Proceedings of WWDU '97 Tokyo, Fifth International Scientific Conference on Work with Display Units : November 3 - 5, 1997, Tokyo Y1 - 1997 N1 - International Scientific Conference on Work with Display Units ; International Scientific Conference on Work with Display Units ; (5 ; 1997.11.03-05 ; Tokyo) SP - 193 EP - 194 PB - - CY - Tokyo ER - TY - JOUR A1 - Wolf, Martin R. A1 - Simon, S. A1 - Schlick, Christopher T1 - Qualitative and Quantitative Analysis of Cooperation / Wolf, M. ; Simon, S. ; Schlick, C. JF - Proceedings : May 26 - 29, 1998, Cannes (France) = Actes : 26 - 29 mai 1998 / INRIA, Institut National de Recherche en Informatique et en Automatique, Unité de recherche ... F. Darses ..., eds Y1 - 1998 N1 - COOP ; Institut National de Recherche en Informatique et en Automatique ; Centre ; (Sophia Antipolis) ; International Conference on the Design of Cooperative Systems ; (3 ; 1998.05.26-29 ; Cannes) ; Conference Internationale sur la Conception de Systèmes Coopératifs ; (3 ; 1998.05.26-29 ; Cannes) ; COOP ; (3 ; 1998.05.26-29 ; Cannes) SP - 1 EP - 5 PB - - CY - Cannes ER - TY - JOUR A1 - Wolf, Martin R. A1 - Luczak, Holger T1 - Computer Supported Communication and Cooperation – Making Information Aware / Luczak, H. ; Wolf, M. JF - Human-computer interaction : proceedings of HCI International '99 (the 8th International Conference on Human-Computer Interaction), Munich, Germany, August 22 - 26, 1999 Y1 - 1999 N1 - HCI - International Conference on Human-Computer Interaction ; 8 (Munich, Germany) : 1999.08.22-26 ; in 2 Bänden SP - 298 EP - 302 PB - Erlbaum CY - Mahwah, NJ ER - TY - JOUR A1 - Wolf, Martin R. A1 - Foltz, Christian A1 - Schlick, Christopher A1 - Luczak, Holger T1 - Groupware support for chemical process design / Wolf, M.; Foltz, C.; Schlick, C.; Luczak, H. JF - Human-computer interaction : proceedings of HCI International '99 (the 8th International Conference on Human-Computer Interaction), Munich, Germany, August 22 - 26, 1999 Y1 - 1999 N1 - HCI - International Conference on Human-Computer Interaction ; 8 (Munich, Germany) : 1999.08.22-26 ; in 2 Bänden SP - 343 EP - 347 PB - Erlbaum CY - Mahwah, NJ ER - TY - JOUR A1 - Wolf, Martin R. A1 - Luczak, Holger A1 - Springer, J. A1 - Simon, S. ED - Miyamoto, Hiroyuki T1 - The role of metaphors in computer supported cooperative work JF - Proceedings of WWDU '97 Tokyo, Fifth International Scientific Conference on Work with Display Units : November 3 - 5, 1997, Tokyo / Y1 - 1997 N1 - International Scientific Conference on Work with Display Units ; International Scientific Conference on Work with Display Units ; (5 ; 1997.11.03-05 ; Tokyo) SP - 191 EP - 192 PB - - CY - Tokyo ER - TY - JOUR A1 - Wolf, Martin R. T1 - Groupware related task design JF - ACM SIGGROUP Bulletin. 21 (2000), H. 2 Y1 - 2000 SP - 5 EP - 8 PB - - ER - TY - JOUR A1 - Wolf, Martin R. A1 - Foltz, Christian A1 - Luczak, Holger A1 - Eggersmann, M. T1 - Entwurf eines Referenzszenarios zur Analyse und Gestaltung von Entwicklungsprozessen in der verfahrenstechnischen Industrie / Foltz, C.; Wolf, M.; Luczak, H.; Eggersmann, M.; Schneider, R.; Marquardt, W. JF - Komplexe Arbeitssysteme - Herausforderung für Analyse und Gestaltung : Bericht zum 46. Arbeitswissenschaftlichen Kongress der Gesellschaft für Arbeitswissenschaft vom 15. - 18. März 2000 ; [Technische Universität Berlin] Y1 - 2000 SN - 3-9806222-5-8 N1 - Arbeitswissenschaftlicher Kongress <46, 2000, Berlin> SP - 545 EP - 548 PB - GfA-Press CY - Dortmund ER - TY - JOUR A1 - Wolf, Martin R. A1 - Foltz, Christian A1 - Schlick, Christopher A1 - Luczak, Holger T1 - Entwicklung und Evaluation eines groupware-basierten Unterstützungssystems für verfahrenstechnische Entwickler / Wolf, M.; Foltz, C.; Schlick, C.; Luczak, H. JF - Komplexe Arbeitssysteme - Herausforderung für Analyse und Gestaltung : Bericht zum 46. Arbeitswissenschaftlichen Kongress der Gesellschaft für Arbeitswissenschaft vom 15. - 18. März 2000 ; [Technische Universität Berlin] Y1 - 2000 SN - 3-9806222-5-8 N1 - Arbeitswissenschaftlicher Kongress <46, 2000, Berlin> SP - 95 EP - 98 PB - GfA-Press CY - Dortmund ER - TY - JOUR A1 - Wolf, Martin R. A1 - Foltz, Christian A1 - Schlick, Christopher A1 - Luczak, Holger T1 - Development and evaluation of a groupware system to support chemical design processes / Wolf, Martin ; Foltz, Christian ; Schlick, Christopher ; Luczak, Holger JF - International Journal of Human-Computer Interaction . 14 (2002), H. 2 Y1 - 2002 SN - 1044-7318 SP - 181 EP - 198 PB - - ER - TY - JOUR A1 - Wolf, Martin R. A1 - Foltz, Christian A1 - Killich, Stephan A1 - Schmidt, Ludger T1 - Task and Information Modeling for Cooperative Work / Foltz, Christian ; Killich, Stephan ; Wolf, Martin ; Schmidt, Ludger ; Luczak, Holger JF - Systems, social and internationalization design aspects of human-computer interaction / ed. by Michael J. Smith, Gavriel Salvendy Vol. 2 Y1 - 2001 SN - 0-8058-3608-X N1 - International Conference on Human Computer Interaction 9, 2001, New Orleans, La. SP - 172 EP - 176 PB - - ER - TY - JOUR A1 - Kern, Alexander A1 - Schelthoff, Christof A1 - Mathieu, Moritz T1 - Detaillierte Berechnung der Einfangwirksamkeiten von Fangeinrichtungen JF - Elektro-Praktiker N2 - Im Beitrag wird zunächst das Verfahren eines dynamischen elektro-geometrischen Modells vorgestellt. Dieses arbeitet im Gegensatz zum klassischen Blitzkugel-Verfahren nicht mit konstanten Radien; vielmehr wird der Radius der Blitzkugel variiert. Dabei werden ausschließlich vorhandene und in internationalen Normen anerkannte Ergebnisse, blitzphysikalische Grundlagen und Untersuchungen verwendet, und auf deren Grundlage ein numerisches Verfahren erarbeitet. Mit dem dynamischen elektro-geometrischen Modell werden dann einige Beispiele des Schutzes mit Fangstangen, die gemäß dem klassischen Blitzkugel-Verfahren nach DIN EN 62305-3 für die Schutzklassen I – II – III – IV geplant sind, untersucht. Es wird gezeigt, dass die Einfangwirksamkeiten wesentlich höher sind als in der Normenreihe DIN EN 62305 selbst angegeben. Grund dafür ist die Tatsache, dass das Blitzkugel-Verfahren sehr konservativ aufgebaut ist und dem Planer von Blitzschutzsystemen nur die möglichen Stellen für einen Einschlag aufzeigt, ohne eine Bewertung der Einschlagshäufigkeit zu liefern. Andererseits bedeutet dies jedoch, dass man mit dem klassischen Blitzkugel-Verfahren stets auf der „sicheren Seite“ liegt. Y1 - 2012 SN - 0013-5569 VL - 66 IS - 4 PB - Huss Medien CY - Berlin ER - TY - JOUR A1 - Kallweit, Stephan A1 - Korculanin, O. A1 - Fröhlig, F. A1 - Gabi, M. A1 - Mattern, P. T1 - Photogrammetrische Rekonstruktion von Partikelpositionen mittels Rückprojektion für 3D-PIV JF - Lasermethoden in der Strömungsmesstechnik : 19. Fachtagung, 6. - 8. September 2011, Ilmenau ; [Tagungsband enthält ... Beiträge, die anlässlich der 19. Fachtagaung "Lasermethoden in der Strömungsmesstechnik" ... vorgetragen und diskutiert wurden] / veranst. von der Deutschen Gesellschaft für Laser-Anemometrie GALA e.V. Hrsg. A. Thess... Y1 - 2011 SN - 978-3-9805613-7-2 N1 - Fachtagung Lasermethoden in der Strömungsmesstechnik <19, 2011, Ilmenau> ; Deutsche Gesellschaft für Laser-Anemometrie SP - 28/1 EP - 28/6 PB - Dt. Ges. für Laser-AnemometrieGALA e. V. CY - Karlsruhe ER - TY - JOUR A1 - Haselgruber, Nikolaus A1 - Mautner, Karin A1 - Thiele, Jan T1 - Usage Space Analysis for Reliability Testing JF - Quality and Reliability Engineering International N2 - During the development process of a complex technical product, one widely used and important technique is accelerated testing where the applied stress on a component is chosen to exceed the reference stress, i.e. the stress encountered in field operation, in order to reduce the time to failure. For that, the reference stress has to be known. Since a complex technical product may fail regarding numerous failure modes, stress in general is highly dimensional rather than scalar. In addition, customers use their products individually, i.e. field operation should be described by a distribution rather than by one scalar stress value. In this paper, a way to span the customer usage space is shown. It allows the identification of worst case reference stress profiles in significantly reduced dimensions with minimal loss of information. The application example shows that even for a complex product like a combustion engine, stress information can be compressed significantly. With low measurement effort it turned out that only three reference stress cycles were sufficient to cover a broad range of customer stress variety. Y1 - 2010 U6 - https://doi.org/10.1002/qre.1155 SN - 1099-1638 N1 - Special Issue: Business and Industrial Statistics: Developments and Industrial Practices in Quality and Reliability VL - 26 IS - 8 SP - 877 EP - 885 PB - Wiley CY - New York ER - TY - JOUR A1 - Havermann, Marc A1 - Haertig, J. A1 - Rey, C. A1 - George, F. T1 - PIV measurements in Mach 3.5 and 4.5 shock tunnel flow / Haertig, J. ; Havermann, M. ; Rey, C. ; George, F. Y1 - 2001 N1 - AIAA-2001-699 Aerospace Sciences Meeting and Exhibit, 39th, Reno, NV, Jan. 8-11, 2001 PB - - ER - TY - JOUR A1 - Havermann, Marc T1 - Systematic Shock Tube Experiments on Vortex Ring Generation and Propagation / Havermann, M. ; Kainuma, M. ; Takayama, K. JF - Shock waves : proceedings of the 25th International Symposium on Shock Waves-ISSW25, July 17 - 22, 2005, Bangalore, India / ed.: G. Jagadeesh Y1 - 2006 SN - 978-81-7371571-6 N1 - International Symposium on Shock Waves ; 25 (Bangalore) : 2005.07.17-22 ISSW ; 25 (Bangalore) : 2005.07.17-22 PB - Universities Pr. CY - Hyderabad ER - TY - JOUR A1 - Lustfeld, H. A1 - Pithan, C. A1 - Reißel, Martin T1 - Metallic electrolyte composites in the framework of the brick-layer model JF - Journal of the European Ceramic Society N2 - It is well known that the already large dielectric constants of some electrolytes like BaTiO₃ can be enhanced further by adding metallic (e.g. Ni, Cu or Ag) nanoparticles. The enhancement can be quite large, a factor of more than 1000 is possible. The consequences for the properties will be discussed in the present paper applying a brick-layer model (BLM) for calculating dc-resistivities of thin layers and a modified one (PBLM) that includes percolation for calculating dielectric properties of these materials. The PBLM results in an at least qualitative description and understanding of the physical phenomena: This model gives an explanation for the steep increase of the dielectric constant below the percolation threshold and why this increase is connected to a dramatic decrease of the breakdown voltage as well as the ability of storing electrical energy. We conclude that metallic electrolyte composites like BaTiO₃ are not appropriate for energy storage. Y1 - 2012 U6 - https://doi.org/10.1016/j.jeurceramsoc.2011.10.017 SN - 0955-2219 VL - 32 IS - 4 SP - 859 EP - 864 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Havermann, Marc A1 - Kainuma, M. A1 - Takayama, K. T1 - Influence of Physical and Geometrical Parameters on Vortex Rings Generated by a Shock Tube / Havermann, M. ; Kainuma, M. ; Takayama, K. JF - Non-lethal options enhancing security and stability : 3rd European Symposium on Non-Lethal Weapons, May 10 - 12, 2005, Ettlingen, Germany / ICT, Fraunhofer-Institut Chemische Technologie; European Working Group Non-Lethal Weapons Y1 - 2005 N1 - European Symposium on Non-Lethal Weapons ; (3 ; 2005.5.10-12 ; Ettlingen); V 24 PB - ICT CY - Pfinztal ER - TY - JOUR A1 - Havermann, Marc A1 - Moeglin, J.-P. T1 - ISL's Research on Systems with Controlled Effects for Non-Lethal Applications / Moeglin, J.-P. ; Havermann, M. et al. JF - Non-lethal options enhancing security and stability : 3rd European Symposium on Non-Lethal Weapons, May 10 - 12, 2005, Ettlingen, Germany / ICT, Fraunhofer-Institut Chemische Technologie; European Working Group Non-Lethal Weapons Y1 - 2005 N1 - European Symposium on Non-Lethal Weapons ; (3 ; 2005.5.10-12 ; Ettlingen); P 35 PB - ICT CY - Pfinztal ER - TY - JOUR A1 - Havermann, Marc A1 - Ende, H. A1 - Seiler, F. A1 - Schwenzer, M. T1 - Shock tunnel measurement of the interaction amplification factor for a hot gas side jet in a supersonic cross flow / Havermann, M. ; Ende, H. ; Seiler, F. ; Schwenzer, M. JF - Shock Waves : Proceedings of the 24th International Symposium on Shock Waves Beijing, China July 11-16, 2004 / edited by Z. Jiang Y1 - 2005 SN - 978-3-540-22497-6 SP - 113 EP - 118 PB - Springer CY - Berlin ER - TY - JOUR A1 - Havermann, Marc A1 - Beylich, A. E. T1 - Performance and Limitations of the Laser-Induced Fluorescence Measurement Technique and the Established Experimental Methods for the Study of Supersonic Mixing / Havermann, M. ; Beylich, A. E. JF - International Journal of heat and technology. 15 (1997), H. 2 Y1 - 1997 SP - 3 EP - 10 PB - - ER - TY - JOUR A1 - Havermann, Marc T1 - Effects of the shock tube open-end shape on vortex loops released from it / Kainuma, M. ; Havermann, M. ; Sun, M. ; Takayama, K. JF - Shock Waves : Proceedings of the 24th International Symposium on Shock Waves Beijing, China July 11-16, 2004 / edited by Z. Jiang Y1 - 2005 SN - 978-3-540-22497-6 SP - 505 EP - 510 PB - Springer CY - Berlin ER - TY - JOUR A1 - Havermann, Marc A1 - Seiler, F. A1 - Boller, F. A1 - Mangold, P. T1 - Operation of the ISL transonic shock tube in a high subsonic flow regime / Seiler, F. ; Havermann, M. ; Boller, F. ; Mangold, P. ; Takayama K. JF - Shock Waves : Proceedings of the 24th International Symposium on Shock Waves Beijing, China July 11-16, 2004 / edited by Z. Jiang Y1 - 2005 SN - 978-3-540-22497-6 SP - 307 EP - 312 PB - Springer CY - Berlin ER - TY - JOUR A1 - Pichler, A. A1 - George, A. A1 - Seiler, F. A1 - Srulijes, J. A1 - Havermann, Marc T1 - Doppler Picture Velocimetry (DPV) applied to hypersonics JF - Shock Waves [Elektronische Ressource] : 26th International Symposium on Shock Waves, Volume 1 / edited by Klaus Hannemann, Friedrich Seiler Y1 - 2009 SN - 978-3-540-85168-4 N1 - International Symposium on Shock Waves ; (26 ; 2007.07.15-20 ; Göttingen) ; ISSW ; (26 ; 2007.07.15-20 ; Göttingen) SP - 503 EP - 508 PB - Springer CY - Berlin ER - TY - JOUR A1 - Havermann, Marc A1 - Seiler, F. A1 - George, A. A1 - Leopold, F. T1 - Planar Velocity Visualization in High-Speed Wedge Flow using Doppler Picture Velocimetry (DPV) compared with Particle Image Velocimetry (PIV) / Seiler, F. ; Havermann, M. ; George, A. ; Leopold, F. ; Srulijes, J. JF - Journal of Visualization. 6 (2003), H. 3 Y1 - 2003 SN - 1343-8875 SP - 253 EP - 262 PB - - ER - TY - JOUR A1 - Havermann, Marc A1 - Haertig, J. A1 - Rey, C. A1 - George, A. T1 - PIV Measurements in Shock Tunnels and Shock Tubes / Havermann, M. ; Haertig, J. ; Rey, C. ; George, A. JF - Particle Image Velocimetry : New Developments and Recent Applications Y1 - 2008 SN - 978-3-540-73528-1 N1 - Topics in applied physics. Vol 112. SP - 429 EP - 442 PB - Springer CY - Berlin ER - TY - JOUR A1 - Fornaciari, Andrea A1 - Guidetti, Marco A1 - Havermann, Marc A1 - Lettini, Antonio T1 - Maccine mobili più efficienti JF - Fluidotecnica N2 - Secondo le attuali normative tutte le macchine mobili, entro il 2012, dovranno essere soggette a un incremento di efficienza energetica. Un’evoluzione del sistema idraulico potrà contribuire in maniera significativa al miglioramento richiesto. Elettronica e idraulica sempre più protagoniste. Y1 - 2010 IS - 345 SP - 11 EP - 14 PB - Quine Business Publisher CY - Milano ER - TY - JOUR A1 - Havermann, Marc A1 - Seiler, F. A1 - Georges, A. A1 - Srulijes, J. T1 - Progress in Doppler picture velocimetry (DPV) / Seiler, F. ; George, A. ; Srulijes, J. ; Havermann, M. JF - Experiments in Fluids. 44 (2008), H. 3 Y1 - 2008 SN - 1432-1114 SP - 389 EP - 395 PB - - ER - TY - JOUR A1 - Havermann, Marc A1 - Haertig, J. A1 - Rey, C. A1 - George, A. T1 - Particle image velocimetry in mach 3.5 and 4.5 shock-tunnel flows / Haertig, J. ; Havermann, M. ; Rey, C. ; George, A. JF - AIAA journal. 40 (2002), H. 6 Y1 - 2002 SN - 0001-1452 N1 - Printausgabe in der Bereichsbibliothek Eupener Str. Signatur: 23 Z 701 SP - 1056 EP - 1060 PB - - ER - TY - JOUR A1 - Havermann, Marc A1 - Seiler, F. A1 - Georges, A. A1 - Leopold, F. T1 - Das Dopplerbildverfahren (DPV) des ISL zur Messung der Strömungsgeschwindigkeit in einer Ebene / Seiler, F. ; Georges, A. ; Leopold, F. ; Srulijes, J. ; Havermann, M. JF - Lasermethoden in der Strömungsmesstechnik, 10. Fachtagung, Deutsche Gesellschaft für Laser-Anemometrie GALA, Rostock, DE, 10.-12. Sep, 2002 Y1 - 2002 SN - 3-86009-233-2 SP - 11.1 EP - 11.6 PB - Univ. CY - Rostock ER - TY - JOUR A1 - Lettini, Antonio A1 - Havermann, Marc A1 - Guidetti, Marco A1 - Fornaciari, Andrea T1 - Improved functionalities and energy saving potential on mobile machines combining electronics with flow sharing valve and variable displacement pump JF - IFK 7, 7th International Fluid Power Conference, Efficiency through Fluid Power, 7. Internationales Fluidtechnisches Kolloquium, Workshop Proceedings, Vol. 3, Aachen, DE, 22.-24. Mar, 2010 Y1 - 2010 SN - 978-3-940565-92-1 N1 - IFK, 7, Internationales Fluidtechnisches Kolloquium, 7., Aachen, DE, 2010-03-22 - 2010-03-24 SP - 103 EP - 114 PB - - ER - TY - JOUR A1 - Havermann, Marc A1 - Seiler, F. T1 - Boundary Layer Influence on Supersonic Jet/Cross-Flow Interaction in Hypersonic Flow / Havermann, M. ; Seiler, F. JF - Notes on Numerical Fluid Mechanics and Multidisciplinary Design. 92 (2006) Y1 - 2006 SN - 1612-2909 N1 - New results in numerical and experimental fluid mechanics ; V ; ISBN 978-3-540-33287-9 SP - 281 EP - 288 PB - - ER - TY - JOUR A1 - Kern, Alexander A1 - Scheibe, Klaus T1 - Die neuen internationalen Blitzschutz-Standards der Reihe IEC 62305:2010 : Überblick und Stand der Umsetzung in die nationale Normenreihe DIN EN 62305 JF - 9. VDE/ABB-Blitzschutztagung : Vorträge der 9. VDE/ABB-Fachtagung vom 27. bis 28. Oktober 2011 in Neu-Ulm / Veranst.: Ausschuss für Blitzschutz und Blitzforschung (ABB) im VDE Verband der Elektrotechnik Elektronik Informationstechnik e.V. Wiss. Tagungsleitung: K. Stimper Y1 - 2011 SN - 978-3-8007-3380-4 N1 - VDE/ABB-Blitzschutztagung ; (9 ; 2011.10.27-28 ; Neu-Ulm) SP - 7 EP - 12 PB - VDE-Verl. CY - Berlin ER - TY - JOUR A1 - Bäcker, Matthias A1 - Raue, Markus A1 - Schusser, Sebastian A1 - Jeitner, C. A1 - Breuer, L. A1 - Wagner, P. A1 - Poghossian, Arshak A1 - Förster, Arnold A1 - Mang, Thomas A1 - Schöning, Michael Josef T1 - Microfluidic chip with integrated microvalves based on temperature- and pH-responsive hydrogel thin films JF - Physica Status Solidi (a) N2 - Two types of microvalves based on temperature-responsive poly(N-isopropylacrylamide) (PNIPAAm) and pH-responsive poly(sodium acrylate) (PSA) hydrogel films have been developed and tested. The PNIPAAm and PSA hydrogel films were prepared by means of in situ photopolymerization directly inside the fluidic channel of a microfluidic chip fabricated by combining Si and SU-8 technologies. The swelling/shrinking properties and height changes of the PNIPAAm and PSA films inside the fluidic channel were studied at temperatures of deionized water from 14 to 36 °C and different pH values (pH 3–12) of Titrisol buffer, respectively. Additionally, in separate experiments, the lower critical solution temperature (LCST) of the PNIPAAm hydrogel was investigated by means of a differential scanning calorimetry (DSC) and a surface plasmon resonance (SPR) method. Mass-flow measurements have shown the feasibility of the prepared hydrogel films to work as an on-chip integrated temperature- or pH-responsive microvalve capable to switch the flow channel on/off. Y1 - 2012 U6 - https://doi.org/10.1002/pssa.201100763 SN - 1862-6319 VL - 209 IS - 5 SP - 839 EP - 845 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Funke, Harald A1 - Robinson, A. E. T1 - Development of a new test rig for a micro scale hydrogen combustion chamber JF - Proceedings of the 2nd European Conference for Aero-Space Sciences : July 1 - 6, 2007, Brussels, Belgium Y1 - 2007 N1 - European Conference for Aerospace Sciences <2, 2007, Brüssel> ; EUCASS <2, 2007, Brüssel> ; Paper No. 22 SP - 1 EP - 8 PB - - ER - TY - JOUR A1 - Backes, Klaus A1 - Adam, Mario A1 - Gottschald, Beng Jonas A1 - Faber, Christian A1 - Henneböhl, Friedrich-Gregor A1 - Lanz, Marco A1 - Anthrakidis, Anette T1 - KWKK-Anlagen im Feldtest. Optimaler Betrieb durch Verbesserungen bei Regelung und Hydraulik JF - Die Kälte- und Klimatechnik Y1 - 2012 SN - 0343-2246 IS - 2 PB - Gentner CY - Stuttgart ER - TY - JOUR A1 - Schuba, Marko A1 - Höfken, H. A1 - Schaefer, T. T1 - Smartphone Forensik JF - Hakin9 : Practical Protection (2012) Y1 - 2012 SN - 1733-7186 SP - 10 EP - 20 PB - - ER - TY - JOUR A1 - Chwallek, Constanze A1 - Engelen, Andreas A1 - Oswald, Monika A1 - Brettel, Malte T1 - Die Wir­kung des Füh­rungs­ver­hal­tens des Top-Ma­nage­ments auf die un­ter­neh­me­ri­sche Ori­en­tie­rung – ein 5-Län­der-Ver­gleich JF - Zfbf : Schmalenbachs Zeitschrift für betriebswirtschaftliche Forschung Y1 - 2012 SN - 0341-2687 IS - 2 SP - 138 EP - 165 PB - Springer Fachmedien CY - Wiesbaden ER - TY - JOUR A1 - Abouzar, Maryam H. A1 - Poghossian, Arshak A1 - Cherstvy, Andrey G. A1 - Pedraza, Angela M. A1 - Ingebrandt, Sven A1 - Schöning, Michael Josef T1 - Label-free electrical detection of DNA by means of field-effect nanoplate capacitors: Experiments and modeling JF - Physica Status Solidi (a) N2 - Label-free electrical detection of consecutive deoxyribonucleic acid (DNA) hybridization/denaturation by means of an array of individually addressable field-effect-based nanoplate silicon-on-insulator (SOI) capacitors modified with gold nanoparticles (Au-NP) is investigated. The proposed device detects charge changes on Au-NP/DNA hybrids induced by the hybridization or denaturation event. DNA hybridization was performed in a high ionic-strength solution to provide a high hybridization efficiency. On the other hand, to reduce the screening of the DNA charge by counter ions and to achieve a high sensitivity, the sensor signal induced by the hybridization and denaturation events was measured in a low ionic-strength solution. High sensor signals of about 120, 90, and 80 mV were registered after the DNA hybridization, denaturation, and re-hybridization events, respectively. Fluorescence microscopy has been applied as reference method to verify the DNA immobilization, hybridization, and denaturation processes. An electrostatic charge-plane model for potential changes at the gate surface of a nanoplate field-effect sensor induced by the DNA hybridization has been developed taking into account both the Debye length and the distance of the DNA charge from the gate surface. Y1 - 2012 U6 - https://doi.org/10.1002/pssa.201100710 SN - 1862-6319 VL - 209 SP - 925 EP - 934 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Bäcker, Matthias A1 - Rakowski, D. A1 - Poghossian, Arshak A1 - Biselli, Manfred A1 - Wagner, Patrick A1 - Schöning, Michael Josef T1 - Chip-based amperometric enzyme sensor system for monitoring of bioprocesses by flow-injection analysis JF - Journal of Biotechnology N2 - A microfluidic chip integrating amperometric enzyme sensors for the detection of glucose, glutamate and glutamine in cell-culture fermentation processes has been developed. The enzymes glucose oxidase, glutamate oxidase and glutaminase were immobilized by means of cross-linking with glutaraldehyde on platinum thin-film electrodes integrated within a microfluidic channel. The biosensor chip was coupled to a flow-injection analysis system for electrochemical characterization of the sensors. The sensors have been characterized in terms of sensitivity, linear working range and detection limit. The sensitivity evaluated from the respective peak areas was 1.47, 3.68 and 0.28 μAs/mM for the glucose, glutamate and glutamine sensor, respectively. The calibration curves were linear up to a concentration of 20 mM glucose and glutamine and up to 10 mM for glutamate. The lower detection limit amounted to be 0.05 mM for the glucose and glutamate sensor, respectively, and 0.1 mM for the glutamine sensor. Experiments in cell-culture medium have demonstrated a good correlation between the glutamate, glutamine and glucose concentrations measured with the chip-based biosensors in a differential-mode and the commercially available instrumentation. The obtained results demonstrate the feasibility of the realized microfluidic biosensor chip for monitoring of bioprocesses. Y1 - 2013 U6 - https://doi.org/10.1016/j.jbiotec.2012.03.014 SN - 0168-1656 VL - 163 IS - 4 SP - 371 EP - 376 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Timme, Michael A1 - Günnewig, Sebastian T1 - Betriebskostenabrechnung - Die Pflicht des Vermieters zur Beachtung des Wirtschaftlichkeitsgebots JF - Der Miet-Rechts-Berater : MietRB ; Miete, Immobilien, Wohnungseigentum N2 - Mit seiner aktuellen Entscheidung (BGH v. 6.11.2011 – VIII ZR 340/10, MDR 2011, 1095 = MietRB MDR 2011, 337) hat der BGH die Darlegungs- und Beweislast für einen Verstoß gegen das Gebot der Wirtschaftlichkeit bei der Abrechnung von Betriebskosten konkretisiert. Der Beitrag erläutert anhand der Hintergründe des Gebotes der Wirtschaftlichkeit die Konsequenzen für die Praxis. Y1 - 2012 SN - 1612-040X IS - 3 SP - 83 EP - 88 PB - Verlag Dr. Otto Schmidt CY - Köln ER - TY - JOUR A1 - Schneider, Bettina A1 - Schneider, Wilhelm T1 - Externes Rechnungswesen nach BilMoG: Grundelemente und Aufbau JF - Das Wirtschaftsstudium : wisu ; Zeitschrift für Ausbildung, Examen, Berufseinstieg und Fortbildung Y1 - 2012 SN - 0340-3084 VL - 41 IS - 3 SP - 332 EP - 337 PB - Lange CY - Düsseldorf ER - TY - JOUR A1 - Grinsven, Bart van A1 - Bon, Natalie vanden A1 - Strauven, Hannelore A1 - Grieten, Lars A1 - Murib, Mohammed A1 - Jiménez Monroy, Kathia L. A1 - Janssens, Stoffel D. A1 - Haenen, Ken A1 - Schöning, Michael Josef A1 - Vermeeren, Veronique A1 - Ameloot, Marcel A1 - Michiels, Luc A1 - Thoelen, Ronald A1 - Ceuninck, Ward de A1 - Wagner, Patrick T1 - Heat-Transfer Resistance at Solid-Liquid Interfaces: A Tool for The Detection of Single Nucleotide Polymorphisms in DNA. JF - ACS Nano N2 - In this article, we report on the heat-transfer resistance at interfaces as a novel, denaturation-based method to detect single-nucleotide polymorphisms in DNA. We observed that a molecular brush of double-stranded DNA grafted onto synthetic diamond surfaces does not notably affect the heat-transfer resistance at the solid-to-liquid interface. In contrast to this, molecular brushes of single-stranded DNA cause, surprisingly, a substantially higher heat-transfer resistance and behave like a thermally insulating layer. This effect can be utilized to identify ds-DNA melting temperatures via the switching from low- to high heat-transfer resistance. The melting temperatures identified with this method for different DNA duplexes (29 base pairs without and with built-in mutations) correlate nicely with data calculated by modeling. The method is fast, label-free (without the need for fluorescent or radioactive markers), allows for repetitive measurements, and can also be extended toward array formats. Reference measurements by confocal fluorescence microscopy and impedance spectroscopy confirm that the switching of heat-transfer resistance upon denaturation is indeed related to the thermal on-chip denaturation of DNA. Y1 - 2012 U6 - https://doi.org/10.1021/nn300147e SN - 1936-086X VL - 6 IS - 3 SP - 2712 EP - 2721 PB - ACS Publications CY - Washington, DC ER - TY - JOUR A1 - Arida, Hassan A. A1 - Al-haddad, Ameera A1 - Schöning, Michael Josef T1 - New Solid-State Organic Membrane Based Lead-Selective Micro-Electrode JF - International Journal of Electrochemical Science. 6 (2011), H. 9 Y1 - 2011 SN - 1452-3981 SP - 3858 EP - 3867 ER - TY - JOUR A1 - Spiess, Elmar A1 - Wilfried, Reichardt A1 - Alvarez, Gerardo A1 - Gottrup, Marcus A1 - Öhlschläger, Peter T1 - An Artificial PAP Gene Breaks Self-tolerance and Promotes Tumor Regression in the TRAMP Model for Prostate Carcinoma JF - Molecular Therapy Y1 - 2011 SN - 1525-0016 VL - 20 IS - 3 SP - 555 EP - 564 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Heuermann, Holger A1 - Hillebrand, Jürgen A1 - Sadeghfam, Arash T1 - Novel Concept of a Digital SigmaDelta-PLL-Phase-Shift-Modulator / Hillebrand, Jürgen ; Sadeghfam, Arash ; Heuermann, Holger Y1 - 2008 SN - 978-3-8007-3086-5 N1 - Microwave Conference (GeMIC), 2008 German SP - 123 EP - 126 ER - TY - JOUR A1 - Immel, Timo A. A1 - Groth, Ulrich A1 - Huhn, Thomas A1 - Öhlschläger, Peter T1 - Titanium salan complexes displays strong antitumor properties in vitro and in vivo in mice JF - PLoS ONE N2 - The anticancer activity of titanium complexes has been known since the groundbreaking studies of Köpf and Köpf-Maier on titanocen dichloride. Unfortunately, possibly due to their fast hydrolysis, derivatives of titanocen dichloride failed in clinical studies. Recently, the new family of titanium salan complexes containing tetradentate ONNO ligands with anti-cancer properties has been discovered. These salan complexes are much more stabile in aqueous media. In this study we describe the biological activity of two titanium salan complexes in a mouse model of cervical cancer. High efficiency of this promising complex family was demonstrated for the first time in vivo. From these data we conclude that titanium salan complexes display very strong antitumor properties exhibiting only minor side effects. Our results may influence the chemotherapy with metallo therapeutics in the future. Y1 - 2011 U6 - https://doi.org/10.1371/journal.pone.0017869 VL - 6 IS - 3 PB - Plos CY - San Francisco, California, US ER - TY - JOUR A1 - Leurs, Ulrike A1 - Mezo, Gabor A1 - Öhlschläger, Peter A1 - Orban, Erika A1 - Marquard, Andrea A1 - Manea, Marilena T1 - Design, synthesis, in vitro stability and cytostatic effect of multifunctional anticancer drug-bioconjugates containing GnRH-III as a targeting moiety JF - Peptide Science N2 - Bioconjugates containing the GnRH-III hormone decapeptide as a targeting moiety are able to deliver chemotherapeutic agents specifically to cancer cells expressing GnRH receptors, thereby increasing their local efficacy while limiting the peripheral toxicity. However, the number of GnRH receptors on cancer cells is limited and they desensitize under continuous hormone treatment. A possible approach to increase the receptor mediated tumor targeting and consequently the cytostatic effect of the bioconjugates would be the attachment of more than one chemotherapeutic agent to one GnRH-III molecule. Here we report on the design, synthesis and biochemical characterization of multifunctional bioconjugates containing GnRH-III as a targeting moiety and daunorubicin as a chemotherapeutic agent. Two different drug design approaches were pursued. The first one was based on the bifunctional [4Lys]-GnRH-III (Glp-His-Trp-Lys-His-Asp-Trp-Lys-Pro-Gly-NH2) containing two lysine residues in positions 4 and 8, whose ϵ-amino groups were used for the coupling of daunorubicin. In the second drug design, the native GnRH-III (Glp-His-Trp-Ser-His-Asp-Trp-Lys-Pro-Gly-NH2) was used as a scaffold; an additional lysine residue was coupled to the ϵ-amino group of 8Lys in order to generate two free amino groups available for conjugation of daunorubicin. The in vitro stability/degradation of all synthesized compounds was investigated in human serum, as well as in the presence of rat liver lysosomal homogenate. Their cellular uptake was determined on human breast cancer cells and the cytostatic effect was evaluated on human breast, colon and prostate cancer cell lines. Compared with a monofunctional compound, both drug design approaches resulted in multifunctional bioconjugates with increased cytostatic effect. Y1 - 2012 U6 - https://doi.org/10.1002/bip.21640 SN - 1097-0282 VL - 98 IS - 1 SP - 1 EP - 10 PB - Wiley CY - New York, NY ER -