TY - JOUR A1 - Abouzar, Maryam H. A1 - Pedraza, A. M. A1 - Schöning, Michael Josef A1 - Poghossian, Arshak T1 - Label-free DNA hybridization and denaturation detection by means of field-effect nanoplate SOI capacitors functionalized with gold nanoparticles JF - Procedia Engineering N2 - A new approach for a label-free electrical detection of DNA hybridization and denaturation using an array of individually addressable field-effect nanoplate SOI (silicon-on-insulator) capacitors functionalized with gold nanoparticles is presented. By using a constant-capacitance measuring setup in a differential mode, signal changes of ∼110 mV and ∼70 mV have been registered after the DNA hybridization and denaturation events, respectively. Y1 - 2010 U6 - https://doi.org/10.1016/j.proeng.2010.09.259 SN - 1877-7058 N1 - Eurosensor XXIV Conference, 5-8 September 2010, Linz, Austria VL - 5 SP - 918 EP - 921 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Abouzar, Maryam H. A1 - Poghossian, Arshak A1 - Siqueira, José R. Jr. A1 - Oliveira, Osvaldo N. Jr. A1 - Moritz, Werner A1 - Schöning, Michael Josef T1 - Capacitive electrolyte-insulator-semiconductor structures functionalised with a polyelectrolyte/enzyme multilayer: New strategy for enhanced field-effect biosensing JF - Physica Status Solidi (A). 207 (2010), H. 4 Y1 - 2010 SN - 1862-6300 N1 - Special Issue: Engineering of Functional Interfaces EnFI 2009 SP - 884 EP - 890 ER - TY - JOUR A1 - Aggeloussis, Nickos A1 - Giannakou, Erasmia A1 - Albracht, Kirsten A1 - Arampatzis, Adamantios T1 - Reproducibility of fascicle length and pennation angle of gastrocnemius medialis in human gait in vivo JF - Gait and Posture N2 - The purpose of the current study was to examine the reproducibility of fascicle length and pennation angle of gastrocnemius medialis while human walking. To the best of our knowledge, this is the first study of the reproducibility of fascicle length and pennation angle of gastrocnemius medialis in vivo during human gait. Twelve males performed 10 gait trials on a treadmill, in 2 separate days. B-mode ultrasonography, with the ultrasound probe firmly adjusted in the transverse and frontal planes using a special cast, was used to measure the fascicle length and the pennation angle of the gastrocnemius medialis (GM). A Vicon 624 system with three cameras operating at 120 Hz was also used to record the ankle and knee joint angles. The results showed that measurements of fascicle length and pennation angle showed high reproducibility during the gait cycle, both within the same day and between different days. Moreover, the root mean square differences between the repeated waveforms of both variables were very small, compared with their ranges (fascicle length: RMS = ∼3 mm, range: 38–63 mm; pennation angle: RMS = ∼1.5°, range: 22–32°). However, their reproducibility was lower compared to the joint angles. It was found that representative data have to be derived by a wide number of gait trials (fascicle length ∼six trials, pennation angle more than 10 trials), to assure the reliability of the fascicle length and pennation angle in human gait. Y1 - 2010 U6 - https://doi.org/10.1016/j.gaitpost.2009.08.249 SN - 0966-6362 VL - 31 IS - 1 SP - 73 EP - 77 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Akimbekov, Nuraly S. A1 - Zhubanova, A. A. A1 - Mansurov, Z. A. A1 - Digel, Ilya A1 - Artmann, Gerhard A1 - Temiz Artmann, Aysegül T1 - Use of Carbonized Rise Shell for the local treatment of wounds JF - Eurasian ChemTech Journal N2 - On the model of musculocutaneous wound in rats, the effect of applicative sorption by carbonized rise shell (CRS) on the healing of festering wound was studied. It has been shown, that cytological changes end with rapid scar formation. The use of CRS at the period of severe purulent wound contributes to its favorable course, prevents the development of complications of the animals from sepsis. Y1 - 2010 U6 - https://doi.org/10.18321/ectj35 SN - 2522-4867 VL - 12 IS - 2 SP - 133 EP - 138 PB - Institute of Combustion Problems CY - Almaty ER - TY - JOUR A1 - Arampatzis, Adamantios A1 - Peper, Andreas A1 - Bierbaum, Stefanie A1 - Albracht, Kirsten T1 - Plasticity of human Achilles tendon mechanical and morphological properties in response to cyclic strain JF - Journal of Biomechanics N2 - The purpose of the current study in combination with our previous published data (Arampatzis et al., 2007) was to examine the effects of a controlled modulation of strain magnitude and strain frequency applied to the Achilles tendon on the plasticity of tendon mechanical and morphological properties. Eleven male adults (23.9±2.2 yr) participated in the study. The participants exercised one leg at low magnitude tendon strain (2.97±0.47%), and the other leg at high tendon strain magnitude (4.72±1.08%) of similar frequency (0.5 Hz, 1 s loading, 1 s relaxation) and exercise volume (integral of the plantar flexion moment over time) for 14 weeks, 4 days per week, 5 sets per session. The exercise volume was similar to the intervention of our earlier study (0.17 Hz frequency; 3 s loading, 3 s relaxation) allowing a direct comparison of the results. Before and after the intervention ankle joint moment has been measured by a dynamometer, tendon–aponeurosis elongation by ultrasound and cross-sectional area of the Achilles tendon by magnet resonance images (MRI). We found a decrease in strain at a given tendon force, an increase in tendon–aponeurosis stiffness and tendon elastic modulus of the Achilles tendon only in the leg exercised at high strain magnitude. The cross-sectional area (CSA) of the Achilles tendon did not show any statistically significant (P>0.05) differences to the pre-exercise values in both legs. The results indicate a superior improvement in tendon properties (stiffness, elastic modulus and CSA) at the low frequency (0.17 Hz) compared to the high strain frequency (0.5 Hz) protocol. These findings provide evidence that the strain magnitude applied to the Achilles tendon should exceed the value, which occurs during habitual activities to trigger adaptational effects and that higher tendon strain duration per contraction leads to superior tendon adaptational responses. Y1 - 2010 U6 - https://doi.org/10.1016/j.jbiomech.2010.08.014 SN - 0021-9290 VL - 43 IS - 16 SP - 3073 EP - 3079 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Beer, S. A1 - Streun, M. A1 - Hombach, T. A1 - Buehler, J. A1 - Jahnke, S. A1 - Khodaverdi, M. A1 - Larue, H. A1 - Minwuyelet, S. A1 - Parl, C. A1 - Roeb, G. A1 - Schurr, U. A1 - Ziemons, Karl T1 - Design and initial performance of PlanTIS: a high-resolution positron emission tomograph for plants JF - Physics in Medicine and Biology N2 - Positron emitters such as 11C, 13N and 18F and their labelled compounds are widely used in clinical diagnosis and animal studies, but can also be used to study metabolic and physiological functions in plants dynamically and in vivo. A very particular tracer molecule is 11CO2 since it can be applied to a leaf as a gas. We have developed a Plant Tomographic Imaging System (PlanTIS), a high-resolution PET scanner for plant studies. Detectors, front-end electronics and data acquisition architecture of the scanner are based on the ClearPET™ system. The detectors consist of LSO and LuYAP crystals in phoswich configuration which are coupled to position-sensitive photomultiplier tubes. Signals are continuously sampled by free running ADCs, and data are stored in a list mode format. The detectors are arranged in a horizontal plane to allow the plants to be measured in the natural upright position. Two groups of four detector modules stand face-to-face and rotate around the field-of-view. This special system geometry requires dedicated image reconstruction and normalization procedures. We present the initial performance of the detector system and first phantom and plant measurements. Y1 - 2010 U6 - https://doi.org/10.1088/0031-9155/55/3/006 SN - 1361-6560 VL - 55 IS - 3 SP - 635 EP - 646 PB - IOP CY - Bristol ER - TY - JOUR A1 - Beging, Stefan A1 - Mlynek, Daniela A1 - Hataihimakul, Sudkanung A1 - Poghossian, Arshak A1 - Baldsiefen, Gerhard A1 - Busch, Heinz A1 - Laube, Norbert A1 - Kleinen, Lisa A1 - Schöning, Michael Josef T1 - Field-effect calcium sensor for the determination of the risk of urinary stone formation JF - Sensors and Actuators B: Chemical. 144 (2010), H. 2 Y1 - 2010 N1 - 22nd International Conference on Eurosensors - Dresden, Germany, 7-10 September 2008 ; Eurosensors ; (22, 2008, Dresden) SP - 374 EP - 379 ER - TY - JOUR A1 - Behbahani, Mehdi A1 - Mai, A. A1 - Bergmann, B. A1 - Waluga, C. A1 - Behr, M. A1 - Tran, L. A1 - Vonderstein, K. A1 - Mottaghy, K. T1 - Modeling and Numerical Simulation of Blood Damage Y1 - 2010 N1 - Posterpresentation ; Umbrella Symposium "Modelling and Simulation in Medicine, Engineering and Sciences", Forschungszentrum Jülich, January 18-20, 2010 ER - TY - JOUR A1 - Behbahani, Mehdi A1 - Mai, A. A1 - Waluga, C. A1 - Bergmann, B. A1 - Tran, L. A1 - Vonderstein, K. A1 - Behr, M. A1 - Mottaghy, K. T1 - Numerical Modeling of Flow-Related Thrombus Formation under Physiological and Non-Physiological Flow Conditions JF - Acta Physiologica Y1 - 2010 SN - 1748-1716 N1 - Joint Congress of the Scandinavian and German Physiological Societies, Copenhagen, Denmark, March 27-30, 2010 VL - 198 IS - Supplement 677 SP - 185 ER - TY - JOUR A1 - Behbahani, Mehdi A1 - Nam, J. A1 - Waluga, C. A1 - Behr, M. A1 - Pasquali, M. A1 - Mottaghy, K. T1 - Modeling and Numerical Analysis of Platelet Activation, Adhesion and Aggregation in Artificial Organs Y1 - 2010 U6 - https://doi.org/10.1097/01.mat.0000369377.65122.a3 N1 - Posterpresentation American Society of Artificial Organs (ASAIO), Baltimore, USA, May 27-29, 2010 VL - 56 IS - 2 SP - 85 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - JOUR A1 - Behbahani, Mehdi A1 - Probst, M. A1 - Mai, A. A1 - Behr, M. A1 - Tran, L. A1 - Vonderstein, K. A1 - Mottaghy, K. T1 - Numerical Prediction of Blood Damage in Biomedical Devices Y1 - 2010 N1 - Posterpresentation ; Biomedica Congress, Aachen, March 17-18, 2010 ER - TY - JOUR A1 - Behbahani, Mehdi A1 - Probst, M. A1 - Mai, A. A1 - Tran, L. A1 - Vonderstein, K. A1 - Keschenau, P. A1 - Linde, T. A1 - Steinseifer, U. A1 - Behr, M. A1 - Mottaghy, K. T1 - The influence of high shear on thrombosis and hemolysis in artificial organs JF - The International Journal of Artificial Organs Y1 - 2010 SN - 0391-3988 VL - 33 IS - 7 SP - 426 EP - 426 PB - Sage CY - Thousand Oaks ER - TY - JOUR A1 - Berretz, Frank A1 - Skorupa, Sascha A1 - Sander, Volker A1 - Belloum, Adam T1 - Towards an actor-driven workflow management system for grids JF - Proceedings of 2010 International Symposium on Collaborative Technologies and Systems N2 - Currently, most workflow management systems in Grid environments provide push-oriented job distribution strategies, where jobs are explicitly delegated to resources. In those scenarios the dedicated resources execute submitted jobs according to the request of a workflow engine or Grid wide scheduler. This approach has various limitations, particularly if human interactions should be integrated in workflow execution. To support human interactions with the benefit of enabling inter organizational computation and community approaches, this poster paper proposes the idea of a pull-based task distribution strategy. Here, heterogeneous resources, including human interaction, should actively select tasks for execution from a central repository. This leads to special demands regarding security issues like access control. In the established push-based job execution the resources are responsible for granting access to workflows and job initiators. In general this is done by access control lists, where users are explicitly mapped to local accounts according to their policies. In the pull-based approach the resources actively apply for job executions by sending requests to a central task repository. This means that every resource has to be able to authenticate against the repository to be authorized for task execution. In other words the authorization is relocated from the resources to the repository. The poster paper introduces current work regarding to the mentioned security aspects in the pull-based approach within the scope of the project “HiX4AGWS”. KW - scheduling KW - engines KW - resource management KW - grid computing KW - access control KW - distribution strategy KW - authorization KW - security KW - humans KW - workflow management software Y1 - 2010 SN - 978-1-4244-6619-1 U6 - https://doi.org/10.1109/CTS.2010.5478458 N1 - 2010 International Symposium on Collaborative Technologies and Systems, 17-21 May 2010, Chicago, IL, USA SP - 611 EP - 616 PB - IEEE CY - Piscataway, NJ ER - TY - JOUR A1 - Bialonski, Stephan A1 - Horstmann, Marie-Therese A1 - Lehnertz, Klaus T1 - From brain to earth and climate systems: Small-world interaction networks or not? JF - Chaos: An Interdisciplinary Journal of Nonlinear Science N2 - We consider recent reports on small-world topologies of interaction networks derived from the dynamics of spatially extended systems that are investigated in diverse scientific fields such as neurosciences, geophysics, or meteorology. With numerical simulations that mimic typical experimental situations, we have identified an important constraint when characterizing such networks: indications of a small-world topology can be expected solely due to the spatial sampling of the system along with the commonly used time series analysis based approaches to network characterization. Y1 - 2010 U6 - https://doi.org/10.1063/1.3360561 SN - 1089-7682 VL - 20 IS - 1 PB - AIP Publishing CY - Melville, NY ER - TY - JOUR A1 - Bohrn, Ulrich A1 - Stütz, Evamaria A1 - Fleischer, Maximilian A1 - Schöning, Michael Josef T1 - Real-time detection of CO by eukaryotic cells JF - Procedia Engineering N2 - In this contribution, we focus on the detection of toxic gases with living eukaryotic cells. A cell-based gas sensor system, able to measure the effects of direct exposure of gases to cells in real-time, was set up. Impedance data as well as oxygen consumption of Chinese hamster lung fibroblast cells (V79) were analysed upon exposure to carbon monoxide (CO). The CO (diluted in wet synthetic air) affects the cell respiration as indicated by an attenuated respiration signal after the CO exposure as well as an instant increase of the capacitive part of the impedance signal during the gas exposure. Y1 - 2010 SN - 1877-7058 N1 - Eurosensor XXIV Conference, 5-8 September 2010, Linz, Austria VL - 5 SP - 17 EP - 20 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Buniatyan, Vahe V. A1 - Abouzar, Maryam H. A1 - Martirosyan, Norayr W. A1 - Schubert, Jürgen A1 - Gevorgian, Spartak A1 - Schöning, Michael Josef A1 - Poghossian, Arshak T1 - pH-sensitive properties of barium strontium titanate (BST) thin films prepared by pulsed laser deposition technique JF - Physica Status Solidi (A). 207 (2010), H. 4 Y1 - 2010 SN - 1862-6300 N1 - Special Issue: Engineering of Functional Interfaces EnFI 2009 SP - 824 EP - 830 ER - TY - JOUR A1 - Bäcker, Matthias A1 - Poghossian, Arshak A1 - Abouzar, Maryam H. A1 - Wenmackers, Sylvia A1 - Janssens, Stoffel D. A1 - Haenen, Ken A1 - Wagner, Patrick A1 - Schöning, Michael Josef T1 - Capacitive field-effect (bio-)chemical sensors based on nanocrystalline diamond films JF - Diamond Electronics and Bioelectronics — Fundamentals to Applications III, edited by P. Bergonzo, [u.a.] Y1 - 2010 N1 - MRS Proceedings Volume 1203 paper 1203-J17-31 ; Mater. Res. Soc. Sympos. Proc. Vol 1203 (2010) ; Materials Research Society SP - 1 EP - 6 ER - TY - JOUR A1 - Bäcker, Matthias A1 - Poghossian, Arshak A1 - Schöning, Michael Josef A1 - Schnitzler, Thomas A1 - Biselli, Manfred A1 - Zang, Werner A1 - Wagner, Patrick T1 - Entwicklung eines modularen festkörperbasierten Sensorsystems für die Überwachung von Zellkulturfermentationen JF - Tagungsband: Sensoren und Messsysteme 2010 N2 - In diesem Beitrag werden Ergebnisse der Entwicklung eines modularen festkörperbasierten Sensorsystems für die Überwachung von Zellkulturfermentationen präsentiert. Zur Messung der Elektrolytleitfähigkeit wurde das Layout von Interdigitalelektroden angepasst, um in vergleichsweise gut leitenden Elektrolyten zu messen. Durch Quervernetzung von Glucose-Oxidase mit Glutaraldehyd und Immobilisierung auf einer Platinelektrode wurde ein amperometrischer Glucosesensor mit einem linearen Messbereich von bis zu 2 mM und einer Sensitivität von 168 nA/mM realisiert. Y1 - 2010 SN - 978-3-8007-3260-9 N1 - Sensoren und Messsysteme 2010 - 15. ITG/GMA-Fachtagung, 18.05.2010 - 19.05.2010 in Nürnberg SP - 688 EP - 698 PB - VDE Verlag CY - Berlin ER - TY - JOUR A1 - Garhofer, Gerhard A1 - Bek, Toke A1 - Boehm, Andreas G. A1 - Gherghel, Doina A1 - Grundwald, Juan A1 - Jeppesen, Peter A1 - Kergoat, Hélène A1 - Kotliar, Konstantin A1 - Lanzl, Ines A1 - Lovasik, John V. A1 - Nagel, Edgar A1 - Vilser, Walthard A1 - Orgul, Selim A1 - Schmetterer, Leopold T1 - Use of the retinal vessel analyzer in ocular blood flow research JF - Acta Ophthalmol N2 - The present article describes a standard instrument for the continuous online determination of retinal vessel diameters, the commercially available retinal vessel analyzer. This report is intended to provide informed guidelines for measuring ocular blood flow with this system. The report describes the principles underlying the method and the instruments currently available, and discusses clinical protocol and the specific parameters measured by the system. Unresolved questions and the possible limitations of the technique are also discussed. Y1 - 2010 U6 - https://doi.org/10.1111/j.1755-3768.2009.01587.x SN - 1755-3768 VL - 88 IS - 7 SP - 717 EP - 722 PB - Wiley-Blackwell CY - Oxford ER - TY - JOUR A1 - Gerhards, Michael A1 - Belloum, Adam A1 - Berretz, Frank A1 - Sander, Volker A1 - Skorupa, Sascha T1 - A history-tracing XML-based provenance framework for workflows JF - The 5th Workshop on Workflows in Support of Large-Scale Science N2 - The importance of validating and reproducing the outcome of computational processes is fundamental to many application domains. Assuring the provenance of workflows will likely become even more important with respect to the incorporation of human tasks to standard workflows by emerging standards such as WS-HumanTask. This paper addresses this trend by an actor-based workflow approach that actively support provenance. It proposes a framework to track and store provenance information automatically that applies for various workflow management systems. In particular, the introduced provenance framework supports the documentation of workflows in a legally binding way. The authors therefore use the concept of layered XML documents, i.e. history-tracing XML. Furthermore, the proposed provenance framework enables the executors (actors) of a particular workflow task to attest their operations and the associated results by integrating digital XML signatures. KW - workflow KW - provenance KW - framework KW - containers KW - humans KW - synchronization KW - libraries KW - history KW - concrete KW - XML Y1 - 2010 SN - 978-1-4244-8989-3 U6 - https://doi.org/10.1109/WORKS.2010.5671873 N1 - The 5th Workshop on Workflows in Support of Large-Scale Science, 14 Nov. 2010, New Orleans, USA PB - IEEE CY - New York ER - TY - JOUR A1 - Grajewski, Matthias A1 - Köster, Michael A1 - Turek, Stefam T1 - Numerical analysis and implementational aspects of a new multilevel grid deformation method JF - Applied Numerical Mathematics N2 - Recently, we introduced and mathematically analysed a new method for grid deformation (Grajewski et al., 2009) [15] we call basic deformation method (BDM) here. It generalises the method proposed by Liao et al. (Bochev et al., 1996; Cai et al., 2004; Liao and Anderson, 1992) [4], [6], [20]. In this article, we employ the BDM as core of a new multilevel deformation method (MDM) which leads to vast improvements regarding robustness, accuracy and speed. We achieve this by splitting up the deformation process in a sequence of easier subproblems and by exploiting grid hierarchy. Being of optimal asymptotic complexity, we experience speed-ups up to a factor of 15 in our test cases compared to the BDM. This gives our MDM the potential for tackling large grids and time-dependent problems, where possibly the grid must be dynamically deformed once per time step according to the user's needs. Moreover, we elaborate on implementational aspects, in particular efficient grid searching, which is a key ingredient of the BDM. Y1 - 2010 U6 - https://doi.org/10.1016/j.apnum.2010.03.017 SN - 0168-9274 VL - 60 IS - 8 SP - 767 EP - 781 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Grottke, O. A1 - Braunschweig, T. A1 - Philippen, B. A1 - Gatzweiler, Karl-Heinz A1 - Gronloh, N. A1 - Staat, Manfred A1 - Rossaint, R. A1 - Tolba, R. T1 - A New Model for Blunt Liver Injuries in the Swine JF - European Surgical Research. 44 (2010), H. 2 Y1 - 2010 SN - 1421-9921 SP - 65 EP - 73 ER - TY - JOUR A1 - Heinzel, Alexander A1 - Schäfer, Ralf A1 - Müller, Hans-Wilhelm A1 - Schieffer, Andre A1 - Ingenhag, Ariane A1 - Eickhoff, Simon B. A1 - Northoff, Georg A1 - Franz, Matthias A1 - Hautzel, Hubertus T1 - Increased Activation of the Supragenual Anterior Cingulate Cortex during Visual Emotional Processing in Male Subjects with High Degrees of Alexithymia: An Event-Related fMRI Study JF - Psychotherapy and Psychosomatics N2 - Background: One of the most prominent neurobiological models of alexithymia assumes an altered function of the anterior cingulate cortex (ACC) as the crucial neural correlate of alexithymia. So far functional imaging studies have yielded inconclusive results. Therefore, we tested this hypothesis in healthy alexithymics and nonalexithymics in an event-related fMRI study. Methods: Thirty high- and 30 low-alexithymic right-handed male subjects (selected by the 20-item Toronto Alexithymia Scale, TAS-20) were investigated with event-related fMRI using a picture viewing paradigm. The stimuli consisted of happy, fearful and neutral facial expressions (Ekman-Friesen) as well as positive, negative and neutral pictures from the International Affective Picture System. Results: Contrasting the high-alexithymic with the low-alexithymic group we observed increased activation of the supragenual ACC for different emotional valences as well as for different emotional stimuli. Moreover, there was a positive correlation of the ACC with the individual TAS-20 scores but no correlations with the individual Beck Depression Inventory scores. Additionally, there was no difference in activity of the amygdala. Conclusions: We demonstrated that the supragenual ACC is constantly activated more strongly in alexithymic subjects and that this activation is related to the symptoms of alexithymia and not to associated symptoms such as depression. Therefore, our findings support the hypothesis of an altered function of the ACC in alexithymia. Y1 - 2010 U6 - https://doi.org/10.1159/000320121 SN - 0033-3190 VL - 79 IS - 6 SP - 363 EP - 370 PB - Karger CY - Basel ER - TY - JOUR A1 - Heinzel, Alexander A1 - Schäfer, Ralf A1 - Müller, Hans-Wilhelm A1 - Schieffer, Andre A1 - Ingenhag, Ariane A1 - Northoff, Georg A1 - Franz, Matthias A1 - Hautzel, Hubertus T1 - Differential modulation of valence and arousal in high-alexithymic and low-alexithymic individuals JF - Neuroreport N2 - High-alexithymic individuals are characterized by an impaired ability to identify and communicate emotions whereas low-alexithymic individuals have a wide-ranging ability to deal with emotions. This study examined the hypothesis that valence and arousal modifications of emotional stimuli differentially modulate cortical regions in high-alexithymic and low-alexithymic individuals. To this end, 28 high-alexithymic and 25 low-alexithymic individuals were investigated with event-related fMRI using visual emotional stimuli. We found differential neural activations in the dorsal anterior cingulate, the insula and the amygdala. We suggest that these differences may account for the impaired ability of high-alexithymic individuals to appropriately handle emotional stimuli. Y1 - 2010 U6 - https://doi.org/10.1097/WNR.0b013e32833f38e0 SN - 1473-558X VL - 21 IS - 15 SP - 998 EP - 1002 PB - Lippincott Williams & Wilkins CY - London ER - TY - JOUR A1 - Herzog, Hans A1 - Pietrzyk, Uwe A1 - Shah, N. Jon A1 - Ziemons, Karl T1 - The current state, challenges and perspectives of MR-PET JF - Neuroimage N2 - Following the success of PET/CT during the last decade and the recent increasing proliferation of SPECT/CT, another hybrid imaging instrument has been gaining more and more interest: MR-PET. First combined, simultaneous PET and MR studies carried out in small animals demonstrated the feasibility of the new approach. Concurrently, some prototypes of an MR-PET scanner for simultaneous human brain studies have been built, their performance is being tested and preliminary applications have already been shown. Through this pioneering work, it has become clear that advances in the detector design are necessary for further optimization. Recently, the different issues related to the present state and future prospects of MR-PET were presented and discussed during an international 2-day workshop at the Forschungszentrum Jülich, Germany, held after, and in conjunction with, the 2008 IEEE Nuclear Science Symposium and Medical Imaging Conference in Dresden, Germany on October 27–28, 2008. The topics ranged from small animal MR-PET imaging to human MR-BrainPET imaging, new detector developments, challenges/opportunities for ultra-high field MR-PET imaging and considerations of possible future research and clinical applications. This report presents a critical summary of the contributions made to the workshop. Y1 - 2010 U6 - https://doi.org/10.1016/j.neuroimage.2009.10.036 SN - 1053-8119 VL - 49 IS - 3 SP - 2072 EP - 2082 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Hirschfeld, Julian A. A1 - Lustfeld, Hans A1 - Reißel, Martin A1 - Steffen, Bernhard T1 - A novel scheme for precise diagnostics and effective stabilization of currents in a fuel cell stack JF - International Journal of Energy Research N2 - A novel scheme for detecting inhomogeneous internal currents in a fuel cell stack is presented. In this paper the scheme is investigated for the case that the flow field plates consist of graphite. Then plates of high conductivity, e.g. aluminium between the flow field plates together with small slits in these plates have three effects: (a) Whenever a local inhomogeneity of the electric current occurs at a particular cell in the stack, this will induce a surface current close to that cell perpendicular to the averaged current. This current can be detected. (b) The plates of high conductivity completely prevent the inhomogeneities from spreading to neighbouring cells. (c) Even at the particular cell the inhomogeneity is suppressed as far as possible. Thus this scheme leads to much better diagnostic possibilities and at the same time reduces electric instabilities to an extent, where they probably become harmless. This scheme will first be explained for a simple model to clarify the idea. However, very precise three dimensional computations using realistic parameters are presented, corroborating the results of the simple model. Y1 - 2010 U6 - https://doi.org/10.1002/er.1662 SN - 0363-907X VL - 34 IS - 3 SP - 293 EP - 301 PB - Wiley CY - London ER - TY - JOUR A1 - Hirschfeld, Julian A. A1 - Lustfeld, Hans A1 - Reißel, Martin A1 - Steffen, Bernhard T1 - Tomographic diagnostics of current distributions in a fuel cell stack JF - International Journal of Energy Research N2 - A novel tomographic scheme for analysing the state of any single membrane electrode assembly (MEA) in a stack is suggested. Plates of very high conductivity placed between every fuel cell and slitted in an appropriate manner cause surface currents at well-defined locations of the stack. We show that knowing these surface currents, information about anomalies of the currents in a MEA can be obtained using the methods of tomography. The results are mathematically not unique. However, when assuming plausible defect structures, one can exclude improbable deficiencies by applying a special form of simulated annealing. We present numerical calculations of typical examples demonstrating that the essential defects of the MEA in any single cell of the stack can be detected and their extent can be determined. Y1 - 2010 U6 - https://doi.org/10.1002/er.1634 SN - 0363-907X VL - 34 IS - 3 SP - 284 EP - 292 PB - Wiley CY - London ER - TY - JOUR A1 - Horstmann, Marie-Therese A1 - Bialonski, Stephan A1 - Noenning, Nina A1 - Mai, Heinke A1 - Prusseit, Jens A1 - Wellmer, Jörg A1 - Hinrichs, Hermann A1 - Lehnertz, Klaus T1 - State dependent properties of epileptic brain networks: Comparative graph–theoretical analyses of simultaneously recorded EEG and MEG JF - Clinical Neurophysiology N2 - Objective To investigate whether functional brain networks of epilepsy patients treated with antiepileptic medication differ from networks of healthy controls even during the seizure-free interval. Methods We applied different rules to construct binary and weighted networks from EEG and MEG data recorded under a resting-state eyes-open and eyes-closed condition from 21 epilepsy patients and 23 healthy controls. The average shortest path length and the clustering coefficient served as global statistical network characteristics. Results Independent on the behavioral condition, epileptic brains exhibited a more regular functional network structure. Similarly, the eyes-closed condition was characterized by a more regular functional network structure in both groups. The amount of network reorganization due to behavioral state changes was similar in both groups. Consistent findings could be achieved for networks derived from EEG but hardly from MEG recordings, and network construction rules had a rather strong impact on our findings. Conclusions Despite the locality of the investigated processes epileptic brain networks differ in their global characteristics from non-epileptic brain networks. Further methodological developments are necessary to improve the characterization of disturbed and normal functional networks. Significance An increased regularity and a diminished modulation capability appear characteristic of epileptic brain networks. Y1 - 2010 U6 - https://doi.org/10.1016/j.clinph.2009.10.013 SN - 1388-2457 VL - 121 IS - 2 SP - 172 EP - 185 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Jansen, S. V. A1 - Behbahani, Mehdi A1 - Laumen, M. A1 - Kaufmann, T. A1 - Hormes, M. A1 - Behr, M. A1 - Schmitz-Rode, T. A1 - Steinseifer, U. T1 - Investigation of Steady Flow Through a Realistic Model of the Thoracic Human Aorta Using 3D Stereo PIV and CFD-Simulation JF - ASAIO Journal Y1 - 2010 U6 - https://doi.org/10.1097/01.mat.0000369377.65122.a3 N1 - American Society of Artificial Organs (ASAIO), Baltimore, USA, May 27-29, 2010 VL - 56 IS - 2 SP - 98 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - JOUR A1 - Jansen, Sebastian A1 - Behbahani, Mehdi A1 - Laumen, Marco A1 - Kaufmann, Tim A1 - Hormes, Marcus A1 - Schmitz-Rode, Thomas A1 - Behr, Marek A1 - Steinseifer, Ulrich T1 - 3D Stereo-PIV Validation for CFD-Simulation of Steady Flow through the Human Aorta using Rapid-Prototyping techniques Y1 - 2010 N1 - abstract ; IV International Symposium on Modelling of Physiological Flows, Sardinia, Italy, June 02-05, 2010 ; MPF2010 ER - TY - JOUR A1 - Kirchner, Patrick A1 - Oberländer, Jan A1 - Friedrich, Peter A1 - Rysstad, Gunnar A1 - Berger, Jörg A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Realization of a calorimetric gas sensor on polyimide foil for applications in aseptic food industry JF - Procedia Engineering N2 - A calorimetric gas sensor is presented for the monitoring of gas-phase H2O2 at elevated temperature during sterilization processes in aseptic food industry. The sensor consists of two temperature-sensitive thin-film resistances built up on a polyimide foil with a thickness of 25 μm, which are passivated with a layer of SU-8 photo resist and catalytically activated with manganese(IV) oxide. Instead of an active heating structure, the calorimetric sensor utilizes the elevated temperature of an evaporated H2O2 aerosol. In an experimental set-up, the sensor has shown a sensitivity of 4.78 °C/(%v/v) in a H2O2 concentration range of 0 to 10% v/v at an evaporation temperature of 240 ∘C. Furthermore, the sensor possesses the same, unchanged sensor signal even at varied evaporation temperatures of the gas stream. The sensor characterization demonstrates the suitability of the calorimetric gas sensor for monitoring the efficiency of sterilization processes. Y1 - 2010 U6 - https://doi.org/10.1016/j.proeng.2010.09.098 SN - 1877-7058 N1 - Eurosensor XXIV Conference, 5-8 September 2010, Linz, Austria VL - 5 SP - 264 EP - 267 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Kirchner, Patrick A1 - Spelthahn, Heiko A1 - Schöning, Michael Josef A1 - Henkel, Hartmut A1 - Schneider, Andreas A1 - Friedrich, Peter A1 - Kolstad, Jens A1 - Berger, Jörg T1 - Realisierung eines Polyimid-basierten kalorimetrischen Gassensors zur Inline-Überwachung der H2O2-Konzentration in aseptischen Abfüllsystemen JF - Tagungsband: Sensoren und Messsysteme 2010 N2 - In aseptischen Abfüllsystemen wird Wasserstoffperoxid in der Gasphase aufgrund der stark oxidativen Wirkung zur Packstoffentkeimung eingesetzt. Dabei wird die Effizienz der Entkeimung im Wesentlichen von der vorliegenden H2O2-Konzentration im Packstoff bestimmt. Zur Inline-Überwachung der H2O2-Konzentration wurde ein kalorimetrischer Gassensor auf Basis einer flexiblen Polyimidfolie aus temperatursensitiven Dünnschicht-Widerständen und Mangan(IV)-oxid als katalytische Transducerschicht realisiert. Der Sensor weist ein lineares Ansprechverhalten mit einer Sensitivität von 7,15 °C/Vol.-% in einem H2O2-Konzentrationsbereich von 0 bis 8 Vol.-% auf. Weiterhin wurde zur Auslesung des Sensorsignals eine RFID-Elektronik, bestehend aus einem Sensor-Tag und einer Sende-/Empfangseinheit ausgelegt, sowie eine Abfolge des Messzyklus aufgestellt. Im weiteren Verlauf soll der kalorimetrische Gassensor mit der RFID-Elektronik gekoppelt und in eine Testverpackung zur Inline-Überwachung der H2O2-Konzentration in aseptischen Abfüllsystemen implementiert werden. Y1 - 2010 SN - 978-3-8007-3260-9 N1 - Sensoren und Messsysteme 2010 - 15. ITG/GMA-Fachtagung, 18.05.2010 - 19.05.2010 in Nürnberg SP - 607 EP - 612 PB - VDE Verlag CY - Berlin ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Nagel, Edgar A1 - Vilser, Walthard A1 - Seidova, Seid-Fatima A1 - Lanzl, Ines T1 - Microstructural alterations of retinal arterial blood column along the vessel axis in systemic hypertension JF - Investigative Ophthalmology & Visual Science, IOVS N2 - Purpose: Image analysis by the retinal vessel analyzer (RVA) observes retinal vessels in their dynamic state online noninvasively along a chosen vessel segment. It has been found that high-frequency diameter changes in the retinal artery blood column along the vessel increase significantly in anamnestically healthy volunteers with increasing age and in patients with glaucoma during vascular dilation. This study was undertaken to investigate whether longitudinal sections of the retinal artery blood column are altered in systemic hypertension. Methods: Retinal arteries of 15 untreated patients with essential arterial hypertension (age, 50.9 ± 11.9 years) and of 15 age-matched anamnestically healthy volunteers were examined by RVA. After baseline assessment, a monochromatic luminance flicker (530–600 nm; 12.5 Hz; 20 s) was applied to evoke retinal vasodilation. Differences in amplitude and frequency of spatial artery blood column diameter change along segments (longitudinal arterial profiles) of 1 mm in length were measured and analyzed using Fourier transformation. Results: In the control group, average reduced power spectra (ARPS) of longitudinal arterial profiles did not differ when arteries changed from constriction to dilation. In the systemic hypertension group, ARPS during constriction, baseline, and restoration were identical and differed from ARPS during dilation (P < 0.05). Longitudinal arterial profiles in both groups showed significant dissimilitude at baseline and restoration (P < 0.05). Conclusions: The retinal artery blood column demonstrates microstructural alterations in systemic hypertension and is less irregular along the vessel axis during vessel dilation. These microstructural changes may be an indication of alterations in vessel wall rigidity, vascular endothelial function, and smooth muscle cells in this disease, leading to impaired perfusion and regulation. Y1 - 2010 U6 - https://doi.org/10.1167/iovs.09-3649 SN - 0146-0404 VL - 51 IS - 4 SP - 2165 EP - 2172 PB - ARVO CY - Rockville, Md. ER - TY - JOUR A1 - Kozhalakova, A. A. A1 - Zhubanova, Azhar A. A1 - Mansurov, Z. A. A1 - Digel, Ilya A1 - Tazhibayeva, S. M. A1 - Artmann, Gerhard A1 - Temiz Artmann, Aysegül T1 - Adsorption of bacterial lipopolysaccharides on carbonized rice shell JF - Science of Central Asia Y1 - 2010 SP - 50 EP - 54 ER - TY - JOUR A1 - Kurz, R. A1 - Linder, Peter A1 - Trzewik, Jürgen A1 - Rüffer, M. A1 - Artmann, Gerhard A1 - Digel, Ilya A1 - Rothermel, A. A1 - Robitzki, A. A1 - Temiz Artmann, Aysegül T1 - Contractile tension and beating rates of self-exciting monolayers and 3D-tissue constructs of neonatal rat cardiomyocytes JF - Medical and Biological Engineering and Computing N2 - The CellDrum technology (The term 'CellDrum technology' includes a couple of slightly different technological setups for measuring lateral mechanical tension in various types of cell monolayers or 3D-tissue constructs) was designed to quantify the contraction rate and mechanical tension of self-exciting cardiac myocytes. Cells were grown either within flexible, circular collagen gels or as monolayer on top of respective 1-mum thin silicone membranes. Membrane and cells were bulged outwards by air pressure. This biaxial strain distribution is rather similar the beating, blood-filled heart. The setup allowed presetting the mechanical residual stress level externally by adjusting the centre deflection, thus, mimicking hypertension in vitro. Tension was measured as oscillating differential pressure change between chamber and environment. A 0.5-mm thick collagen-cardiac myocyte tissue construct induced after 2 days of culturing (initial cell density 2 x 10(4) cells/ml), a mechanical tension of 1.62 +/- 0.17 microN/mm(2). Mechanical load is an important growth regulator in the developing heart, and the orientation and alignment of cardiomyocytes is stress sensitive. Therefore, it was necessary to develop the CellDrum technology with its biaxial stress-strain distribution and defined mechanical boundary conditions. Cells were exposed to strain in two directions, radially and circumferentially, which is similar to biaxial loading in real heart tissues. Thus, from a biomechanical point of view, the system is preferable to previous setups based on uniaxial stretching. Y1 - 2010 U6 - https://doi.org/10.1007/s11517-009-0552-y SN - 1741-0444 VL - 48 IS - 1 SP - 59 EP - 65 PB - Springer Nature CY - Cham ER - TY - JOUR A1 - Lanzl, Ines M. A1 - Seidova, Seid-Fatima A1 - Erben, A. A1 - Thürmel, K. A1 - Kotliar, Konstantin T1 - Diffuse stromale Hornhauttrübungen und Veränderungen der Hände JF - Der Ophthalmologe N2 - Bilaterale stromale Hornhauttrübungen sind für den Augenarzt eine differenzialdiagnostische Herausforderung. Im folgenden Beitrag werden 2 Patieninnen (30 und 36 Jahre) mit unterschiedlich stark ausgeprägter stromaler diffuser Hornhauttrübung vorgestellt. Patientin 1 war kleinwüchsig (114 cm) und Patientin 2 normal groß (172 cm). Beide Patientinnen wiesen veränderte Gelenkstrukturen an Hand und Fußgelenken sowie diffuse stromale Hornhauttrübungen auf. Des Weiteren lagen eine Mitral- und Aorteninsuffizienz (Patientin 1) bzw. eine Aorteninsuffizienz (Patientin 2) vor. Die stromalen diffusen Hornhauttrübungen ließen im Zusammenhang mit den Gelenkveränderungen ein Scheie-Syndrom vermuten. Therapeutisch ist bei Patienten mit Visusminderung eine (lamelläre) Keratoplastik sinnvoll. Y1 - 2010 U6 - https://doi.org/10.1007/s00347-009-2066-2 SN - 1433-0423 VL - 107 IS - 4 SP - 363 EP - 365 PB - Springer CY - Berlin ER - TY - JOUR A1 - Leimena, W. A1 - Artmann, Gerhard A1 - Dachwald, Bernd A1 - Temiz Artmann, Aysegül A1 - Gossmann, Matthias A1 - Digel, Ilya T1 - Feasibility of an in-situ microbial decontamination of an ice-melting probe JF - Eurasian Chemico-Technological Journal N2 - Autonomous robotic systems for penetrating thick ice shells with simultaneous collecting of scientific data are very promising devices in both terrestrial (glacier, climate research) and extra-terrestrial applications. Technical challenges in development of such systems are numerous and include 3D-navigation, an appropriate energy source, motion control, etc. Not less important is the problem of forward contamination of the pristine glacial environments with microorganisms and biomolecules from the surface of the probe. This study was devoted to establishing a laboratory model for microbial contamination of a newly constructed ice-melting probe called IceMole and to analyse the viability and amount of the contaminating microorganisms as a function of distance. The used bacterial strains were Bacillus subtilis (ATCC 6051) and Escherichia coli (ATCC 11775). The main objective was development of an efficient and reliable in-situ decontamination method of the melting probe. Therefore, several chemical substances were tested in respect of their efficacy to eliminate bacteria on the surface of the melting probe at low temperature (0 - 5 °C) and at continuous dilution by melted water. Our study has shown that at least 99.9% decontamination of the IceMole can be successfully achieved by the injection of 30% (v/v) hydrogen peroxide and 3% (v/v) sodium hypochlorite into the drilling site. We were able to reproduce this result in both time-dependent and depth-dependent experiments. The sufficient amount of 30% (v/v) H₂O₂ or 3% (v/v) NaClO has been found to be approximately 18 L per cm² of the probe’s surface. Y1 - 2010 SN - 1562-3920 U6 - https://doi.org/10.18321/ectj37 VL - 12 IS - 2 SP - 145 EP - 150 PB - Institute of Combustion Problems CY - Almaty ER - TY - JOUR A1 - Miyamoto, Ko-ichiro A1 - Kaneko, Kazumi A1 - Matsuo, Akira A1 - Wagner, Torsten A1 - Kanoh, Shin`ichiro A1 - Schöning, Michael Josef A1 - Yoshinobu, Tatsuo T1 - Miniaturized chemical imaging sensor system using an OLED display panel JF - Procedia Engineering N2 - The chemical imaging sensor is a semiconductor-based chemical sensor that can visualize the two-dimensional distribution of specific ions or molecules in the solution. In this study, we developed a miniaturized chemical imaging sensor system with an OLED display panel as a light source that scans the sensor plate. In the proposed configuration, the display panel is placed directly below the sensor plate and illuminates the back surface. The measured area defined by illumination can be arbitrarily customized to fit the size and the shape of the sample to be measured. The waveform of the generated photocurrent, the currentvoltage characteristics and the pH sensitivity were investigated and pH imaging with this miniaturized system was demonstrated. Y1 - 2010 U6 - https://doi.org/10.1016/j.proeng.2010.09.160 SN - 1877-7058 N1 - Eurosensor XXIV Conference, 5-8 September 2010, Linz, Austria VL - 5 SP - 516 EP - 519 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Miyamoto, Ko-ichiro A1 - Sugawara, Yuri A1 - Kanoh, Shin´ichiro A1 - Yoshinobu, Tatsuo A1 - Wagner, Torsten A1 - Schöning, Michael Josef T1 - Image correction method for the chemical imaging sensor JF - Sensors and Actuators B: Chemical. 144 (2010), H. 2 Y1 - 2010 N1 - 22nd International Conference on Eurosensors - Dresden, Germany, 7-10 September 2008 ; Eurosensors ; (22, 2008, Dresden) SP - 344 EP - 348 ER - TY - JOUR A1 - Nam, J. A1 - Arora, D. A1 - Behbahani, Mehdi A1 - Probst, M. A1 - Benkowski, R. A1 - Behr, M. A1 - Pasquali, M. T1 - New computational method in hemolysis analysis for artificial heart pump Y1 - 2010 N1 - Posterpresentation ; American Society of Artificial Organs (ASAIO), Baltimore, USA, May 27-29, 2010 ER - TY - JOUR A1 - Nguyen, N.-H. A1 - Raatschen, Hans-Jürgen A1 - Staat, Manfred T1 - A hyperelastic model of biological tissue materials in tubular organs Y1 - 2010 N1 - ECCM 2010, IV European Conference on Computational Mechanics, Paris, France, May 16-21, 2010. SP - 1 EP - 12 ER - TY - JOUR A1 - Pham, Phu Tinh A1 - Vu, Khoi Duc A1 - Tran, Thanh Ngoc A1 - Staat, Manfred T1 - A primal-dual algorithm for shakedown analysis of elastic-plastic bounded linearly kinematic hardening bodies Y1 - 2010 N1 - ECCM 2010, IV European Conference on Computational Mechanics, Paris, France, May 16-21, 2010. SP - 1 EP - 7 ER - TY - JOUR A1 - Poghossian, Arshak A1 - Wagner, Holger A1 - Schöning, Michael Josef T1 - Automatisiertes „wafer level“-Testsystem zur Charakterisierung von siliziumbasierten Chemo- und Biosensoren JF - Tagungsband: Sensoren und Messsysteme 2010 N2 - Es wurde ein automatisiertes, computerunterstütztes Testsystem für die Funktionsprüfung und Charakterisierung von (bio-)chemischen Sensoren auf Waferebene entwickelt und in einen konventionellen Spitzenmessplatz integriert. Das System ermöglicht die Charakterisierung und Identifizierung „funktionstauglicher“ Sensoren bereits auf Waferebene zwischen den einzelnen Herstellungsschritten, wodurch weitere, bisher übliche Verarbeitungsschritte wie das Fixieren, Bonden und Verkapseln für die defekten oder nicht funktionstauglichen Sensorstrukturen entfällt. Außerdem bietet eine speziell entworfene miniaturisierte Durchflussmesszelle die Möglichkeit, bereits auf Waferlevel die Sensitivität, Drift, Hysterese und Ansprechzeit der (bio-)chemischen Sensoren zu charakterisieren. Das System wurde exemplarisch mit kapazitiven, pH-sensitiven EIS- (Elektrolyt-Isolator-Silizium) Strukturen und ISFET- (ionensensitiver Feldeffekttransistor) Strukturen mit verschiedenen Geometrien und Gate-Layouts getestet. Y1 - 2010 SN - 978-3-8007-3260-9 N1 - Sensoren und Messsysteme 2010 - 15. ITG/GMA-Fachtagung, 18.05.2010 - 19.05.2010 in Nürnberg SP - 89 EP - 92 PB - VDE Verlag CY - Berlin ER - TY - JOUR A1 - Pressler, Axel A1 - Esefeld, Katrin A1 - Scherr, Johannes A1 - Ali, Mohammad A1 - Hanssen, Henner A1 - Kotliar, Konstantin A1 - Lanzl, Ines A1 - Halle, Martin A1 - Kaemmerer, Harald A1 - Schmidt-Trucksäss, Arno A1 - Hager, Alfred T1 - Structural alterations of retinal arterioles in adults late after repair of aortic isthmic coarctation JF - The American Journal of Cardiology N2 - Patients after coarctation repair still have an increased risk of cardiovascular or cerebrovascular events. This has been explained by the persisting hypertension and alterations in the peripheral vessels. However, involvement of the central vessels such as the retinal arteries is virtually unknown. A total of 34 patients after coarctation repair (22 men and 12 women; 23 to 58 years old, age range 0 to 32 years at surgical repair) and 34 nonhypertensive controls underwent structural and functional retinal vessel analysis. Using structural analysis, the vessel diameters were measured. Using functional analysis, the endothelium-dependent vessel dilation in response to flicker light stimulation was assessed. In the patients after coarctation repair, the retinal arteriolar diameter was significantly reduced compared to that of the controls (median 182 μm, first to third quartile 171 to 197; vs 197 μm, first to third quartile 193 to 206; p <0.001). These findings were independent of the peripheral blood pressure and age at intervention. No differences were found for venules. The functional analysis findings were not different between the patients and controls (maximum dilation 3.5%, first to third quartile 2.1% to 4.5% vs 3.6%, first to third quartile 2.2% to 4.3%; p = 0.81), indicating preserved autoregulative mechanisms. In conclusion, the retinal artery diameter is reduced in patients after coarctation repair, independent of their current blood pressure level and age at intervention. As a structural marker of chronic vessel damage associated with past, current, or future hypertension, retinal arteriolar narrowing has been linked to stroke incidence. These results indicate an involvement of cerebral microcirculation in aortic coarctation, despite timely repair, and might contribute to explain the increased rate of cerebrovascular events in such patients. Y1 - 2010 U6 - https://doi.org/10.1016/j.amjcard.2009.10.070 SN - 0002-9149 VL - 105 IS - 5 SP - 740 EP - 744 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Probst, M. A1 - Behbahani, Mehdi A1 - Borrmann, E. A1 - Elgeti, S. A1 - Nicolai, M. A1 - Behr, M. T1 - Hemodynamic Modeling for Numerical Analysis and Design of Medical Devices Y1 - 2010 N1 - Posterpresentation ; NIC Symposium 2010 ; 24 - 25 February 2010 Jülich, Germany ER - TY - JOUR A1 - Reisert, Steffen A1 - Henkel, Hartmut A1 - Schneider, Andreas A1 - Schäfer, Daniel A1 - Friedrich, Peter A1 - Berger, Jörg A1 - Schöning, Michael Josef T1 - Development of a handheld sensor system for the online measurement of hydrogen peroxide in aseptic filling systems JF - Physica Status Solidi (A). 207 (2010), H. 4 Y1 - 2010 SN - 1862-6300 N1 - Special Issue: Engineering of Functional Interfaces EnFI 2009 SP - 913 EP - 918 ER - TY - JOUR A1 - Riepl, Herbert Matthias A1 - Pettrak, Jürgen A1 - Faulstich, Martin A1 - Herrmann, Wolfgang Anton T1 - Self metathesis of fatty alcohols and amines to provide monomers for polyester and polyamide products JF - Macromolecular Symposia N2 - Self metathesis of oleochemicals offers a variety of bifunctional compounds, that can be used as monomer for polymer production. Many precursors are in huge scales available, like oleic acid ester (biodiesel), oleyl alcohol (tensides), oleyl amines (tensides, lubricants). We show several ways to produce and separate and purify C18-α,ω-bifunctional compounds, using Grubbs 2nd Generation catalysts, starting from technical grade educts. KW - fatty acid KW - metathesis KW - polyamide KW - polyester KW - renewable resources Y1 - 2010 U6 - https://doi.org/10.1002/masy.200900041 SN - 1521-3900 (eISSN) SN - 0258-0322 SN - 1022-1360 N1 - Special Issue: "Olefin Metathesis" VL - 293 IS - 1 SP - 39 EP - 42 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Kirchner, Patrick A1 - Ng, Yue Ann A1 - Spelthahn, Heiko A1 - Schneider, Andreas A1 - Henkel, Hartmut A1 - Friedrich, Peter A1 - Kolstad, Jens A1 - Berger, Jörg A1 - Keusgen, Michael T1 - Gas sensor investigation based on a catalytically activated thin-film thermopile for H2O2 detection JF - Physica Status Solidi (A). 207 (2010), H. 4 Y1 - 2010 SN - 1862-6300 N1 - Special Issue: Engineering of Functional Interfaces EnFI 2009 SP - 787 EP - 792 ER - TY - JOUR A1 - Siqueira, Jose R. A1 - Maki, Rafael M. A1 - Paulovich, Fernando V. A1 - Werner, Frederik A1 - Poghossian, Arshak A1 - Oliveira, Maria C. F. de A1 - Zucolotto, Valtencir A1 - Oliveira, Osvaldo N. Jr. A1 - Schöning, Michael Josef T1 - Use of Information Visualization Methods Eliminating Cross Talk in Multiple Sensing Units Investigated for a Light-Addressable Potentiometric Sensor JF - Analytical Chemistry (2010) Y1 - 2010 SN - 0003-2700 SP - 61 EP - 65 ER - TY - JOUR A1 - Siqueira, José R. Jr. A1 - Bäcker, Matthias A1 - Poghossian, Arshak A1 - Zucolotto, Valtencir A1 - Oliveira, Osvaldo N. Jr. A1 - Schöning, Michael Josef T1 - Associating biosensing properties with the morphological structure of multilayers containing carbon nanotubes on field-effect devices JF - Physica status solidi (a). 207 (2010), H. 4 Y1 - 2010 SN - 1862-6300 N1 - Special Issue: Engineering of Functional Interfaces EnFI 2009 SP - 781 EP - 786 ER -