TY - CHAP A1 - Janotte, N. A1 - Feckler, G. A1 - Kötter, Jens A1 - Decker, Stefan A1 - Herrmann, Ulf A1 - Schmitz, Mark A1 - Lüpfert, E. T1 - Dynamic performance evaluation of the HelioTrough® collector demonstration loop : towards a new benchmark in parabolic trough qualification T2 - SolarPACES International Conference 2013, Las Vegas, Nevada, USA, 17 - 20 September 2013 : [proceedings]. - Pt. 1. - (Energy procedia ; 49) Y1 - 2014 SN - 978-1-63266-904-9 U6 - http://dx.doi.org/10.1016/j.egypro.2014.03.012 SN - 1876-6102 N1 - Nebent.: Power and Chemical Energy Systems concentrating solar power SP - 109 EP - 117 PB - Curran CY - Red Hook, NY ER - TY - JOUR A1 - Jens, Otto A1 - Kaldenhoff, E. A1 - Kirschner-Hermanns, R. A1 - Mühl, Thomas A1 - Klinge, Uwe T1 - Elongation of textile pelvic floor implants under load is related to complete loss of effective porosity, thereby favoring incorporation in scar plates JF - Journal of biomedical materials research. Part A N2 - Use of textile structures for reinforcement of pelvic floor structures has to consider mechanical forces to the implant, which are quite different to the tension free conditions of the abdominal wall. Thus, biomechanical analysis of textile devices has to include the impact of strain on stretchability and effective porosity. Prolift® and Prolift + M®, developed for tension free conditions, were tested by measuring stretchability and effective porosity applying mechanical strain. For comparison, we used Dynamesh-PR4®, which was designed for pelvic floor repair to withstand mechanical strain. Prolift® at rest showed moderate porosity with little stretchability but complete loss of effective porosity at strain of 4.9 N/cm. Prolift + M® revealed an increased porosity at rest, but at strain showed high stretchability, with subsequent loss of effective porosity at strain of 2.5 N/cm. Dynamesh PR4® preserved its high porosity even under strain, but as consequence of limited stretchability. Though in tension free conditions Prolift® and Prolift + M® can be considered as large pore class I meshes, application of mechanical strain rapidly lead to collapse of pores. The loss of porosity at mechanical stress can be prevented by constructions with high structural stability. Assessment of porosity under strain was found helpful to define requirements for pelvic floor devices. Clinical studies have to prove whether devices with high porosity as well as high structural stability can improve the patients' outcome. Y1 - 2014 U6 - http://dx.doi.org/10.1002/jbm.a.34767 SN - 1552-4965 VL - 102 IS - 4 SP - 1079 EP - 1084 PB - Wiley CY - New York ER - TY - CHAP A1 - Jung, Alexander A1 - Staat, Manfred A1 - Müller, Wolfram ED - Onate, E. T1 - Optimization of the flight style in ski jumping T2 - 11th World Congress on Computational Mechanics (WCCM XI) ; 5th European Conference on Computational Mechanics (ECCM V) ; 6th European Conference on Computational Fluid Dynamics (ECFD VI) ; July 20 - 25, 2014, Barcelona Y1 - 2014 N1 - Das Paper wurde nach der Konferenz überarbeitet. SP - 799 EP - 810 ER - TY - CHAP A1 - Kern, Alexander A1 - Braun, Christian T1 - Risk management according to IEC 62305-2 edition 2: 2010–12 assessment of structures with a risk of explosion T2 - 2014 International Conference on Lightning Protection (ICLP), Shanghai, China N2 - Risk management for structures with a risk of explosion should be considered very carefully when performing a risk analysis according to IEC 62305-2. In contrast to the 2006 edition of the standard, the 2010 edition describes the topic “Structures with a risk of explosion” in more detail. Moreover, in Germany separate procedures and parameters are defined for the risk analysis of structures with a risk of explosion (Supplement 3 of the German DIN EN 62305-2 standard). This paper describes the contents and the relevant calculations of this Supplement 3, together with a numerical example. Y1 - 2014 SP - 1237 EP - 1242 ER - TY - JOUR A1 - Khaydukova, M. M. A1 - Zadorozhnaya, O. A. A1 - Kirsanov, D. O. A1 - Iken, Heiko A1 - Rolka, David A1 - Schöning, Michael Josef A1 - Babain, V. A. A1 - Vlasov, Yu. G. A1 - Legin, A. V. T1 - Multivariate processing of atomic-force microscopy images for detection of the response of plasticized polymeric membranes JF - Russian journal of applied chemistry N2 - The possibility of using the atomic-force microscopy as a method for detection of the analytical signal from plasticized polymeric sensor membranes was analyzed. The surfaces of cadmium-selective membranes based on two polymeric matrices were examined. The digital images were processed with multivariate image analysis techniques. A correlation was found between the surface profile of an ion-selective membrane and the concentration of the ion in solution. Y1 - 2014 U6 - http://dx.doi.org/10.1134/S1070427214030112 SN - 1608-3296 (E-Journal); 1070-4272 (Print) VL - 87 IS - 3 SP - 307 EP - 314 PB - Springer CY - Dordrecht ER - TY - CHAP A1 - Kirchner, Patrick A1 - Reisert, Steffen A1 - Schöning, Michael Josef T1 - Calorimetric gas sensors for hydrogen peroxide monitoring in aseptic food processes T2 - Gas sensing fundamentals. (Springer Series on Chemical Sensors and Biosensors ; 15) N2 - For the sterilisation of aseptic food packages it is taken advantage of the microbicidal properties of hydrogen peroxide (H2O2). Especially, when applied in vapour phase, it has shown high potential of microbial inactivation. In addition, it offers a high environmental compatibility compared to other chemical sterilisation agents, as it decomposes into oxygen and water, respectively. Due to a lack in sensory detection possibilities, a continuous monitoring of the H2O2 concentration was recently not available. Instead, the sterilisation efficacy is validated using microbiological tests. However, progresses in the development of calorimetric gas sensors during the last 7 years have made it possible to monitor the H2O2 concentration during operation. This chapter deals with the fundamentals of calorimetric gas sensing with special focus on the detection of gaseous hydrogen peroxide. A sensor principle based on a calorimetric differential set-up is described. Special emphasis is given to the sensor design with respect to the operational requirements under field conditions. The state-of-the-art regarding a sensor set-up for the on-line monitoring and secondly, a miniaturised sensor for in-line monitoring are summarised. Furthermore, alternative detection methods and a novel multi-sensor system for the characterisation of aseptic sterilisation processes are described. KW - Calorimetric gas sensor KW - Hydrogen peroxide KW - Multi-sensor system Y1 - 2014 SN - 978-3-642-54518-4 (Print) ; 978-3-642-54519-1 (Online) U6 - http://dx.doi.org/10.1007/5346_2013_51 SP - 279 EP - 309 PB - Springer CY - Heidelberg ER - TY - CHAP A1 - Kirsch, Ansgar A1 - Felber, W. A1 - Marcher, Thomas A1 - Fuchs, W. T1 - Geotechnical challenges during design and construction of a ski resort in Azerbaijan T2 - Geotechnics of roads and railways : proceedings of the 15th Danube - European Conference on Geotechnical Engineering : 9-11 September 2014, Vienna, Austria Y1 - 2014 SN - 978‐3‐902593‐01‐6 SP - 757 EP - 762 PB - ÖIAV - Österreichischer Ingenieur- und Architekten-Verein CY - Wien ER - TY - BOOK A1 - Klinkel, Sven A1 - Butenweg, Christoph A1 - Lin, Gao A1 - Holtschoppen, Britta T1 - Seismic design of industrial facilities : Proceedings of the International Conference on Seismic Design of Industrial Facilities (SeDIF) / Sven Klinkel, Christoph Butenweg, Gao Lin, Britta Holtschoppen Editors Y1 - 2014 SN - 978-3-658-02809-1 (Print) ; 978-365-80281-0-7 (E-Book) U6 - http://dx.doi.org/10.1007/978-3-658-02810-7 PB - Springer Vieweg CY - Wiesbaden ER - TY - JOUR A1 - Kluczka, Sven A1 - Eckstein, Julian A1 - Alexopoulos, Spiros A1 - Vaeßen, Christiane A1 - Roeb, Martin T1 - Process simulation for solar steam and dry reforming JF - Energy procedia : Proceedings of the SolarPACES 2013 International Conference N2 - In co-operation with the German Aerospace Center, the Solar-Institut Jülich has been analyzing the different technologies that are available for methanol production from CO2 using solar energy. The aim of the project is to extract CO2 from industrial exhaust gases or directly from the atmosphere to recycle it by use of solar energy. Part of the study was the modeling and simulating of a methane reformer for the production of synthesis gas, which can be operated by solar or hybrid heat sources. The reformer has been simplified in such a way that the model is accurate and enables fast calculations. The developed pseudo-homogeneous one- dimensional model can be regarded as a kind of counter-current heat exchanger and is able to incorporate a steam reforming reaction as well as a dry reforming reaction. Y1 - 2014 U6 - http://dx.doi.org/10.1016/j.egypro.2014.03.092 SN - 1876-6102 (E-Journal) VL - 49 SP - 850 EP - 859 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Knott, Thomas C. A1 - Sofronia, Raluca E. A1 - Gerressen, Marcus A1 - Law, Yuen A1 - Davidescu, Arjana A1 - Savii, George G. A1 - Gatzweiler, Karl-Heinz A1 - Staat, Manfred A1 - Kuhlen, Torsten W. T1 - Preliminary bone sawing model for a virtual reality-based training simulator of bilateral sagittal split osteotomy T2 - Biomedical simulation : 6th International Symposium, ISBMS 2014, Strasbourg, France, October 16-17, 2014 : proceedings (Lecture notes in computer science : vol. 8789) N2 - Successful bone sawing requires a high level of skill and experience, which could be gained by the use of Virtual Reality-based simulators. A key aspect of these medical simulators is realistic force feedback. The aim of this paper is to model the bone sawing process in order to develop a valid training simulator for the bilateral sagittal split osteotomy, the most often applied corrective surgery in case of a malposition of the mandible. Bone samples from a human cadaveric mandible were tested using a designed experimental system. Image processing and statistical analysis were used for the selection of four models for the bone sawing process. The results revealed a polynomial dependency between the material removal rate and the applied force. Differences between the three segments of the osteotomy line and between the cortical and cancellous bone were highlighted. KW - Bone sawing KW - virtual reality KW - training simulator Y1 - 2014 SN - 978-3-319-12057-7 (Online) SN - 978-3-319-12056-0 (Print) U6 - http://dx.doi.org/10.1007/978-3-319-12057-7_1 SP - 1 EP - 10 PB - Springer CY - Cham ER - TY - JOUR A1 - Kronhardt, Valentina A1 - Alexopoulos, Spiros A1 - Reißel, Martin A1 - Sattler, Johannes, Christoph A1 - Hoffschmidt, Bernhard A1 - Hänel, Matthias A1 - Doerbeck, Till T1 - High-temperature thermal storage system for solar tower power plants with open-volumetric air receiver simulation and energy balancing of a discretized model JF - Energy procedia N2 - This paper describes the modeling of a high-temperature storage system for an existing solar tower power plant with open volumetric receiver technology, which uses air as heat transfer medium (HTF). The storage system model has been developed in the simulation environment Matlab/Simulink®. The storage type under investigation is a packed bed thermal energy storage system which has the characteristics of a regenerator. Thermal energy can be stored and discharged as required via the HTF air. The air mass flow distribution is controlled by valves, and the mass flow by two blowers. The thermal storage operation strategy has a direct and significant impact on the energetic and economic efficiency of the solar tower power plants. Y1 - 2014 U6 - http://dx.doi.org/10.1016/j.egypro.2014.03.094 SN - 1876-6102 (E-Journal) ; 1876-6102 (Print) VL - 49 SP - 870 EP - 877 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Küppers, Tobias A1 - Steffen, Victoria A1 - Hellmuth, Hendrik A1 - O'Connell, Timothy A1 - Bongaerts, Johannes A1 - Maurer, Karl-Heinz A1 - Wiechert, Wolfgang T1 - Developing a new production host from a blueprint: Bacillus pumilus as an industrial enzyme producer JF - Microbial cell factories Y1 - 2014 U6 - http://dx.doi.org/10.1186/1475-2859-13-46 SN - 1475-2859 (E-Journal) VL - 13 SP - Article No. 46 PB - BioMed Central CY - London ER - TY - JOUR A1 - Laack, Walter van T1 - Nature is much smarter than expected: the Genetic Code is not degenerate JF - American journal of humanities and social sciences N2 - In any books about genetics it can still today be read that our genetic code is called “degenerate” because it is still believed that 43 = 64 triplets encode the 20 essential amino acids. Indeed we have to assume the inverse law, what means that 34 = 81 exact code positions are really effective for our genetic code and encode the amino acids, compiled to proteins. This very important discovery leads to two completely new results that are limits-overlooking: 1) 34 (=81) genetic code positions mean exactly the same number as there are stable and naturally existing chemical elements in our universe. This famous argument should now lead to some alternative, as well as new fundamental conclusions about our existence. 2) A genetic code positioning system shows that nature is much smarter than expected: mutations are made less dangerous than believed, because they won't be that easily able any more to cause severe damages in the protein-synthesis. This should also lead to some alternative views upon evolution of life. Y1 - 2014 SN - 2329-0781 (Print) ; 2329-079X (Online) VL - Vol. 2 IS - No. 1 SP - 10 EP - 12 ER - TY - JOUR A1 - Laack, Walter van T1 - Therefore Fermat is right JF - American journal of humanities and social sciences : AJHSS N2 - It was Fernat's idea to investigate how many numbers would fulfill the equation according to the Pythagorean Theorem if the exponent were increased to random, e.g. to a3 + b3 = c3. His question became therefore: are there two whole numbers the cubes of which add up to the volume of the cube of a third whole number? He posed this same question, of course, for all kinds of higher exponents, so that the equation could be generalized: is there an integral solution for the equation an + bn = cn, if the exponent n is higher than 2? Although in 1993, the English mathematician Andrew Wiles was able to produce an arithmetical proof for Fermat's famous theorem, I will show that there is a simple logical explanation which is also pragmatic and plausible and what is the result of a fundamental alternative idea how our world seems to be constructed. Y1 - 2014 SN - 2329-079X (E-Journal); 2329-0781 (Print) VL - 2 IS - 2 SP - 117 EP - 120 ER - TY - JOUR A1 - Lagemaat, Miriam W. A1 - Vos, Eline K. A1 - Maas, Marnix C. A1 - Bitz, Andreas A1 - Orzada, Stephan A1 - Uden, Mark J. van A1 - Kobus, Thiele A1 - Heerschap, Arend A1 - Scheenen, Tom W. J. T1 - Phosphorus magnetic resonance spectroscopic imaging at 7 T in patients with prostate cancer JF - Investigative Radiology N2 - Objectives The aim of this study was to identify characteristics of phosphorus (³¹P) spectra of the human prostate and to investigate changes of individual phospholipid metabolites in prostate cancer through in vivo ³¹P magnetic resonance spectroscopic imaging (MRSI) at 7 T. Materials and Methods In this institutional review board–approved study, 15 patients with biopsy-proven prostate cancer underwent T₂-weighted magnetic resonance imaging and 3-dimensional ³¹P MRSI at 7 T. Voxels were selected at the tumor location, in normal-appearing peripheral zone tissue, normal-appearing transition zone tissue, and in the base of the prostate close to the seminal vesicles. Phosphorus metabolite ratios were determined and compared between tissue types. Results Signals of phosphoethanolamine (PE) and phosphocholine (PC) were present and well resolved in most ³¹P spectra in the prostate. Glycerophosphocholine signals were observable in 43% of the voxels in malignant tissue, but in only 10% of the voxels in normal-appearing tissue away from the seminal vesicles. In many spectra, independent of tissue type, 2 peaks resonated in the chemical shift range of inorganic phosphate, possibly representing 2 separate pH compartments. The PC/PE ratio in the seminal vesicles was highly elevated compared with the prostate in 5 patients. A considerable overlap of ³¹P metabolite ratios was found between prostate cancer and normal-appearing prostate tissue, preventing direct discrimination of these tissues. The only 2 patients with high Gleason scores tumors (≥4+5) presented with high PC and glycerophosphocholine levels in their cancer lesions. Conclusions Phosphorus MRSI at 7 T shows distinct features of phospholipid metabolites in the prostate gland and its surrounding structures. In this exploratory study, no differences in ³¹P metabolite ratios were observed between prostate cancer and normal-appearing prostate tissue possibly because of the partial volume effects of small tumor foci in large MRSI voxels. Y1 - 2014 U6 - http://dx.doi.org/10.1097/RLI.0000000000000012 SN - 1536-0210 VL - 49 IS - 5 SP - 363 EP - 372 PB - Lippincott Williams & Wilkins CY - Philadelphia, Pa. ER - TY - JOUR A1 - Leandro, J. A1 - Bung, Daniel B. A1 - Carvalho, R. T1 - Measuring void fraction and velocity fields of a stepped spillway for skimming flow using non-intrusive methods JF - Experiments in fluids Y1 - 2014 U6 - http://dx.doi.org/10.1007/s00348-014-1732-6 SN - 0723-4864 (Print) ; 1432-1114 (Online) IS - 55 SP - Art. 1732 PB - Springer Nature CY - Heidelberg ER - TY - JOUR A1 - Lehnertz, Klaus A1 - Ansmann, Gerrit A1 - Bialonski, Stephan A1 - Dickten, Henning A1 - Geier, Christian A1 - Porz, Stephan T1 - Evolving networks in the human epileptic brain JF - Physica D: Nonlinear Phenomena N2 - Network theory provides novel concepts that promise an improved characterization of interacting dynamical systems. Within this framework, evolving networks can be considered as being composed of nodes, representing systems, and of time-varying edges, representing interactions between these systems. This approach is highly attractive to further our understanding of the physiological and pathophysiological dynamics in human brain networks. Indeed, there is growing evidence that the epileptic process can be regarded as a large-scale network phenomenon. We here review methodologies for inferring networks from empirical time series and for a characterization of these evolving networks. We summarize recent findings derived from studies that investigate human epileptic brain networks evolving on timescales ranging from few seconds to weeks. We point to possible pitfalls and open issues, and discuss future perspectives. Y1 - 2014 U6 - http://dx.doi.org/10.1016/j.physd.2013.06.009 SN - 0167-2789 VL - 267 SP - 7 EP - 15 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Leinhos, Marcel A1 - Schusser, Sebastian A1 - Bäcker, Matthias A1 - Poghossian, Arshak A1 - Schöning, Michael Josef T1 - Micromachined multi-parameter sensor chip for the control of polymer-degradation medium JF - Physica Status Solidi (A) : special issue on engineering and functional interfaces N2 - It is well known that the degradation environment can strongly influence the biodegradability and kinetics of biodegradation processes of polymers. Therefore, besides the monitoring of the degradation process, it is also necessary to control the medium in which the degradation takes place. In this work, a micromachined multi-parameter sensor chip for the control of the polymer-degradation medium has been developed. The chip combines a capacitive field-effect pH sensor, a four-electrode electrolyte-conductivity sensor and a thin-film Pt-temperature sensor. The results of characterization of individual sensors are presented. In addition, the multi-parameter sensor chip together with an impedimetric polymer-degradation sensor was simultaneously characterized in degradation solutions with different pH and electrolyte conductivity. The obtained results demonstrate the feasibility of the multi-parameter sensor chip for the control of the polymer-degradation medium. Y1 - 2014 U6 - http://dx.doi.org/10.1002/pssa.201330364 SN - 1521-396X (E-Journal); 1862-6319 (E-Journal); 0031-8965 (Print); 1862-6300 (Print) VL - 211 IS - 6 SP - 1346 EP - 1351 PB - Wiley-VCH CY - Weinheim ER - TY - CHAP A1 - Lenz, Laura L. A1 - Wolf, Martin ED - Kritz, Willy Christian T1 - Economic evaluation of serious games with the comparative assessment framework COSEGA T2 - The shift from teaching to learning : individual, collective and organizational learning through gaming simulation ; proceedings of the 45th conference of the International Simulation and Gaming Association, Dornbirn 2014 Y1 - 2014 SN - 978-3-7639-5422-3 SP - 374 EP - 386 PB - Bertelsmann CY - [Bielefeld] ER - TY - JOUR A1 - Luisier, Raphaëlle A1 - Lempiäinen, Harri A1 - Scherbichler, Nina A1 - Braeuning, Albert A1 - Geissler, Miriam A1 - Dubost, Valerie A1 - Müller, Arne A1 - Scheer, Nico A1 - Chibout, Salah-Dine A1 - Hara, Hisanori A1 - Picard, Frank A1 - Theil, Diethilde A1 - Couttet, Philippe A1 - Vitobello, Antonio A1 - Grenet, Olivier A1 - Grasl-Kraupp, Bettina A1 - Ellinger-Ziegelbauer, Heidrung A1 - Thomson, John P. A1 - Meehan, Richard R. A1 - Elcombe, Clifford R. A1 - Henderson, Colin J. A1 - Wolf, C. Roland A1 - Schwarz, Michael A1 - Moulin, Pierre A1 - Terranova, Remi A1 - Moggs, Jonathan G. T1 - Phenobarbital Induces Cell Cycle Transcriptional Responses in Mouse Liver Humanized for Constitutive Androstane and Pregnane X Receptors JF - Toxicological Sciences N2 - The constitutive androstane receptor (CAR) and the pregnane X receptor (PXR) are closely related nuclear receptors involved in drug metabolism and play important roles in the mechanism of phenobarbital (PB)-induced rodent nongenotoxic hepatocarcinogenesis. Here, we have used a humanized CAR/PXR mouse model to examine potential species differences in receptor-dependent mechanisms underlying liver tissue molecular responses to PB. Early and late transcriptomic responses to sustained PB exposure were investigated in liver tissue from double knock-out CAR and PXR (CARᴷᴼ-PXRᴷᴼ), double humanized CAR and PXR (CARʰ-PXRʰ), and wild-type C57BL/6 mice. Wild-type and CARʰ-PXRʰ mouse livers exhibited temporally and quantitatively similar transcriptional responses during 91 days of PB exposure including the sustained induction of the xenobiotic response gene Cyp2b10, the Wnt signaling inhibitor Wisp1, and noncoding RNA biomarkers from the Dlk1-Dio3 locus. Transient induction of DNA replication (Hells, Mcm6, and Esco2) and mitotic genes (Ccnb2, Cdc20, and Cdk1) and the proliferation-related nuclear antigen Mki67 were observed with peak expression occurring between 1 and 7 days PB exposure. All these transcriptional responses were absent in CARᴷᴼ-PXRᴷᴼ mouse livers and largely reversible in wild-type and CARʰ-PXRʰ mouse livers following 91 days of PB exposure and a subsequent 4-week recovery period. Furthermore, PB-mediated upregulation of the noncoding RNA Meg3, which has recently been associated with cellular pluripotency, exhibited a similar dose response and perivenous hepatocyte-specific localization in both wild-type and CARʰ-PXRʰ mice. Thus, mouse livers coexpressing human CAR and PXR support both the xenobiotic metabolizing and the proliferative transcriptional responses following exposure to PB. Y1 - 2014 U6 - http://dx.doi.org/https://doi.org/10.1093/toxsci/kfu038 SN - 1094-2025 VL - 139 IS - 2 SP - 501 EP - 511 PB - Oxford University Press CY - Oxford ER - TY - JOUR A1 - Lévesque, Mathieu A1 - Siegwolf, Rolf A1 - Eilmann, Britta A1 - Saurer, Matthias A1 - Rigling, Andreas T1 - Increased water-use efficiency does not lead to enhanced tree growth under xeric and mesic conditions JF - New Phytologist Y1 - 2014 U6 - http://dx.doi.org/10.1111/nph.12772 SN - 1469-8137 (Online) SN - 0028-646X (Print) VL - 203 IS - 1 SP - 94 EP - 109 PB - Wiley-Blackwell CY - Oxford ER - TY - JOUR A1 - Maas, Marnix C. A1 - Vos, Eline K. A1 - Lagemaat, Miriam W. A1 - Bitz, Andreas A1 - Orzada, Stephan A1 - Kobus, Thiele A1 - Kraff, Oliver A1 - Maderwald, Stefan A1 - Ladd, Mark E. A1 - Scheenen, Tom W. J. T1 - Feasibility of T₂-weighted turbo spin echo imaging of the human prostate at 7 tesla JF - Magnetic Resonance in Medicine N2 - Purpose To demonstrate that high quality T₂-weighted (T2w) turbo spin-echo (TSE) imaging of the complete prostate can be achieved routinely and within safety limits at 7 T, using an external transceive body array coil only. Methods Nine healthy volunteers and 12 prostate cancer patients were scanned on a 7 T whole-body system. Preparation consisted of B₀ and radiofrequency shimming and localized flip angle calibration. T₁ and T₂ relaxation times were measured and used to define the T2w-TSE protocol. T2w imaging was performed using a TSE sequence (pulse repetition time/echo time 3000–3640/71 ms) with prolonged excitation and refocusing pulses to reduce specific absorption rate. Results High quality T2w TSE imaging was performed in less than 2 min in all subjects. Tumors of patients with gold-standard tumor localization (MR-guided biopsy or prostatectomy) were well visualized on 7 T imaging (n = 3). The number of consecutive slices achievable within a 10-g averaged specific absorption rate limit of 10 W/kg was ≥28 in all subjects, sufficient for full prostate coverage with 3-mm slices in at least one direction. Conclusion High quality T2w TSE prostate imaging can be performed routinely and within specific absorption rate limits at 7 T with an external transceive body array. Y1 - 2014 U6 - http://dx.doi.org/10.1002/mrm.24818 SN - 1522-2594 VL - 71 IS - 5 SP - 1711 EP - 1719 PB - Wiley-VCH CY - Weinheim ER - TY - CHAP A1 - Macdonald, Malcolm A1 - McGrath, C. A1 - Appourchaux, T. A1 - Dachwald, Bernd A1 - Finsterle, W. A1 - Gizon, L. A1 - Liewer, P. C. A1 - McInnes, Colin R. A1 - Mengali, G. A1 - Seboldt, W. A1 - Sekii, T. A1 - Solanki, S. K. A1 - Velli, M. A1 - Wimmer-Schweingruber, R. F. A1 - Spietz, Peter A1 - Reinhard, Ruedeger ED - Macdonald, Malcolm T1 - Gossamer roadmap technology reference study for a solar polar mission T2 - Advances in solar sailing N2 - A technology reference study for a solar polar mission is presented. The study uses novel analytical methods to quantify the mission design space including the required sail performance to achieve a given solar polar observation angle within a given timeframe and thus to derive mass allocations for the remaining spacecraft sub-systems, that is excluding the solar sail sub-system. A parametric, bottom-up, system mass budget analysis is then used to establish the required sail technology to deliver a range of science payloads, and to establish where such payloads can be delivered to within a given timeframe. It is found that a solar polar mission requires a solar sail of side-length 100–125 m to deliver a ‘sufficient value’ minimum science payload, and that a 2.5 μm sail film substrate is typically required, however the design is much less sensitive to the boom specific mass. Y1 - 2014 SN - 978-3-642-34906-5 U6 - http://dx.doi.org/10.1007/978-3-642-34907-2_17 SP - 243 EP - 257 PB - Springer CY - Berlin, Heidelberg ER - TY - JOUR A1 - Mansurov, Z. A. A1 - Jandosov, J. M. A1 - Kerimkulova, A. R. A1 - Azat, S. A1 - Zhubanova, A. A. A1 - Digel, Ilya A1 - Savistkaya, I. S. A1 - Akimbekov, N. S. A1 - Kistaubaeva, A. S. T1 - Nanostructured carbon materials for biomedical use JF - Eurasian chemico-technological journal : quarterly journal of the International Higher Education Academy of Sciences N2 - One of the priority trends of carbon nanotechnology is creation of nanocomposite systems. Such carbon nanostructured composites were produced using - raw materials based on the products of agricultural waste, such as grape stones, apricot stones, rice husk. These products have a - wide spectrum of application and can be obtained in large quantities. The Institute of Combustion Problems has carried out the work on synthesis of the nanostructured carbon sorbents for multiple applications including the field of biomedicine. The article presents the data on the synthesis and physico-chemical properties of carbonaceous sorbents using physicochemical methods of investigation: separation and purification of biomolecules; isolation of phytohormone - fusicoccin; adsorbent INGO-1 in the form of an adsorption column for blood detoxification, oral (entero) sorbent - INGO-2; the study of efferent and probiotic properties and sorption activity in regard to the lipopolysaccharide (LPS), new biocomposites - based on carbonized rice husk (CRH) and cellular microorganisms; the use of CRH in wound treatment. A new material for blood detoxication (INGO-1) has been obtained. Adsorption of p-cresyl sulfate and indoxyl sulfate has shown that active carbon adsorbent can remove clinically significant level of p-cresyl sulfate and indoxyl sulfate from human plasma. Enterosorbent INGO-2 possesses high adsorption activity in relation to Gram-negative bacteria and their endotoxins. INGO-2 slows down the growth of conditionally pathogenic microorganisms, without having a negative effect on bifido and lactobacteria. The use of enterosorbent INGO-2 for sorption therapy may provide a solution to a complex problem - detoxication of the digestive tract and normalization of the intestinal micro ecology. The immobilized probiotic called "Riso-lact" was registered at the Ministry of Health of the Republic of Kazakhstan as a biologically active food additive. The developed technology is patented and provides production of the medicine in the form of freeze-dried biomass immobilized in vials. Y1 - 2014 U6 - http://dx.doi.org/10.18321/ectj224 SN - 1562-3920 VL - 15 (2013) IS - 3 SP - 209 EP - 217 PB - Institute of Combustion Problems CY - Almaty ER - TY - JOUR A1 - Martin-Gonzalez, Anabel A1 - Kotliar, Konstantin A1 - Rios-Martinez, Jorge A1 - Lanzl, Ines A1 - Navab, Nassir T1 - Mediated-reality magnification for macular degeneration rehabilitation JF - Journal of Modern Optics Y1 - 2014 U6 - http://dx.doi.org/10.1080/09500340.2014.936110 SN - 1362-3044 VL - 61 IS - 17 SP - 1400 EP - 1408 PB - Taylor & Francis CY - London ER - TY - CHAP A1 - McInnes, Colin R. A1 - Bothmer, Volker A1 - Dachwald, Bernd A1 - Geppert, Ulrich R. M. E. A1 - Heiligers, Jeannette A1 - Hilgers, Alan A1 - Johnson, Les A1 - Macdonald, Malcolm A1 - Reinhard, Ruedeger A1 - Seboldt, Wolfgang A1 - Spietz, Peter T1 - Gossamer roadmap technology reference study for a Sub-L1 Space Weather Mission T2 - Advances in solar sailing N2 - A technology reference study for a displaced Lagrange point space weather mission is presented. The mission builds on previous concepts, but adopts a strong micro-spacecraft philosophy to deliver a low mass platform and payload which can be accommodated on the DLR/ESA Gossamer-3 technology demonstration mission. A direct escape from Geostationary Transfer Orbit is assumed with the sail deployed after the escape burn. The use of a miniaturized, low mass platform and payload then allows the Gossamer-3 solar sail to potentially double the warning time of space weather events. The mission profile and mass budgets will be presented to achieve these ambitious goals. Y1 - 2014 SN - 978-3-642-34906-5 (Print) ; 978-3-642-34907-2 (E-Book) SP - 227 EP - 242 PB - Springer CY - Berlin [u.a.] ER - TY - JOUR A1 - Miyamoto, K. A1 - Seki, K. A1 - Wagner, Torsten A1 - Schöning, Michael Josef A1 - Yoshinobu, T. T1 - Enhancement of the spatial resolution of the chemical imaging sensor by a hybrid fiber-optic illumination JF - Procedia Engineering N2 - The chemical imaging sensor, which is based on the principle of the light-addressable potentiometric sensor (LAPS), is a powerful tool to visualize the spatial distribution of chemical species on the sensor surface. The spatial resolution of this sensor depends on the diffusion of photocarriers excited by a modulated light. In this study, a novel hybrid fiber-optic illumination was developed to enhance the spatial resolution. It consists of a modulated light probe to generate a photocurrent signal and a ring of constant light, which suppresses the lateral diffusion of minority carriers excited by the modulated light. It is demonstrated that the spatial resolution was improved from 92 μm to 68 μm. Y1 - 2014 U6 - http://dx.doi.org/10.1016/j.proeng.2014.11.563 SN - 1877-7058 N1 - EUROSENSORS 2014 ; European Conference on Solid-State Transducers <28, 2014> VL - 87 SP - 612 EP - 615 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Miyamoto, Ko-ichiro A1 - Itabashi, Akinori A1 - Wagner, Torsten A1 - Schöning, Michael Josef A1 - Yoshinobu, Tatsuo T1 - High-speed chemical imaging inside a microfluidic channel JF - Sensors and actuators. B: Chemical N2 - In this study, a high-speed chemical imaging system was developed for visualization of the interior of a microfluidic channel. A microfluidic channel was constructed on the sensor surface of the light-addressable potentiometric sensor (LAPS), on which the ion concentrations could be measured in parallel at up to 64 points illuminated by optical fibers. The temporal change of pH distribution inside the microfluidic channel was recorded at a maximum rate of 100 frames per second (fps). The high frame rate allowed visualization of moving interfaces and plugs in the channel even at a flow velocity of 111 mm/s, which suggests the feasibility of plug-based microfluidic devices for flow-injection analysis (FIA). Y1 - 2014 U6 - http://dx.doi.org/10.1016/j.snb.2013.12.090 SN - 1873-3077 (E-Journal); 0925-4005 (Print) VL - 194 SP - 521 EP - 527 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Moseley, Fiona A1 - Halamek, Jan A1 - Kramer, Friederike A1 - Poghossian, Arshak A1 - Schöning, Michael Josef A1 - Katz, Evgeny T1 - An enzyme-based reversible CNOT logic gate realized in a flow system JF - Analyst N2 - An enzyme system organized in a flow device was used to mimic a reversible Controlled NOT (CNOT) gate with two input and two output signals. Reversible conversion of NAD⁺ and NADH cofactors was used to perform a XOR logic operation, while biocatalytic hydrolysis of p-nitrophenyl phosphate resulted in an Identity operation working in parallel. The first biomolecular realization of a CNOT gate is promising for integration into complex biomolecular networks and future biosensor/biomedical applications. Y1 - 2014 U6 - http://dx.doi.org/10.1039/C4AN00133H SN - 1364-5528 (E-Journal) ; 0003-2654 (Print) VL - 139 IS - 8 SP - 1839 EP - 1842 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Murib, Mohammed Sharif A1 - Yeap, Weng-Siang A1 - Martens, Daan A1 - Bienstman, Peter A1 - Ceuninck, Ward de A1 - Grinsven, Bart van A1 - Schöning, Michael Josef A1 - Michiels, Luc A1 - Haenen, Ken A1 - Ameloot, Marcel A1 - Serpengüzel, Ali A1 - Wagner, Patrick T1 - Photonic detection and characterization of DNA using sapphire microspheres JF - Journal of biomedical optics N2 - A microcavity-based deoxyribonucleic acid (DNA) optical biosensor is demonstrated for the first time using synthetic sapphire for the optical cavity. Transmitted and elastic scattering intensity at 1510 nm are analyzed from a sapphire microsphere (radius 500  μm, refractive index 1.77) on an optical fiber half coupler. The 0.43 nm angular mode spacing of the resonances correlates well with the optical size of the sapphire sphere. Probe DNA consisting of a 36-mer fragment was covalently immobilized on a sapphire microsphere and hybridized with a 29-mer target DNA. Whispering gallery modes (WGMs) were monitored before the sapphire was functionalized with DNA and after it was functionalized with single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA). The shift in WGMs from the surface modification with DNA was measured and correlated well with the estimated thickness of the add-on DNA layer. It is shown that ssDNA is more uniformly oriented on the sapphire surface than dsDNA. In addition, it is shown that functionalization of the sapphire spherical surface with DNA does not affect the quality factor (Q≈104) of the sapphire microspheres. The use of sapphire is especially interesting because this material is chemically resilient, biocompatible, and widely used for medical implants. Y1 - 2014 U6 - http://dx.doi.org/10.1117/1.JBO.19.9.097006 SN - 1560-2281 (E-Journal); 1083-3668 (Print) VL - 19 IS - 9 SP - 097006 PB - SPIE CY - Bellingham ER - TY - JOUR A1 - Müller, Martin A1 - Hirschfeld, Julian A1 - Lambertz, Rita A1 - Schulze Lohoff, Andreas A1 - Lustfeld, Hans A1 - Pfeifer, Heinz A1 - Reißel, Martin T1 - Validation of a novel method for detecting and stabilizing malfunctioning areas in fuel cell stacks JF - Journal of power sources N2 - In this paper a setup for detecting malfunctioning areas of MEAs in fuel cell stacks is described. Malfunctioning areas generate electric cross currents inside bipolar plates. To exploit this we suggest bipolar plates consisting not of two but of three layers. The third one is a highly conducting layer and segmented such that the cross currents move along the segments to the surface of the stack where they can be measured by an inductive sensor. With this information a realistic model can be used to detect the malfunctioning area. Furthermore the third layer will prevent any current inhomogeneity of a malfunctioning cell to spread to neighbouring cells in the stack. In this work the results of measurements in a realistic cell setup will be compared with the results obtained in simulation studies with the same configuration. The basis for the comparison is the reliable characterisation of the electrical properties of the cell components and the implication of these results into the simulation model. The experimental studies will also show the limits in the maximum number of segments, which can be used for a reliable detection of cross currents. Y1 - 2014 U6 - http://dx.doi.org/10.1016/j.jpowsour.2014.08.045 SN - 1873-2755 (E-Journal); 0378-7753 (Print) VL - 272 SP - 225 EP - 232 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Nachtrodt, Frederik A1 - Tietsch, Wolfgang A1 - Mostacci, Domiziano A1 - Scherer, Ulrich W. T1 - Set-up and first operation of a plasma oven for treatment of low level radioactive wastes JF - Nuclear technology and radiation protection Y1 - 2014 U6 - http://dx.doi.org/10.2298/NTRP140SS47N SN - 1451-3994 VL - 29 IS - Suppl. SP - 47 EP - 51 PB - VINČA Institute of Nuclear Sciences CY - Belgrad ER - TY - CHAP A1 - Neugebauer, Georg A1 - Brutschy, Lucas A1 - Meyer, Ulrike A1 - Wetzel, Susanne ED - Garcia-Alfaro, Joaquin ED - Lioudakis, Georgios ED - Cuppens-Boulahia, Nora ED - Foley, Simon ED - Fitzgerald, William M. T1 - Privacy-preserving multi-party reconciliation secure in the malicious model T2 - DPM 2013, SETOP 2013: Data Privacy Management and Autonomous Spontaneous Security N2 - The problem of fair and privacy-preserving ordered set reconciliation arises in a variety of applications like auctions, e-voting, and appointment reconciliation. While several multi-party protocols have been proposed that solve this problem in the semi-honest model, there are no multi-party protocols that are secure in the malicious model so far. In this paper, we close this gap. Our newly proposed protocols are shown to be secure in the malicious model based on a variety of novel non-interactive zero-knowledge-proofs. We describe the implementation of our protocols and evaluate their performance in comparison to protocols solving the problem in the semi-honest case. KW - Privacy-enhancing technologies KW - Secure multi-party computation KW - Cryptographic protocols KW - Zero-knowledge proofs KW - Malicious model Y1 - 2014 SN - 978-3-642-54567-2 (Print) SN - 978-3-642-54568-9 (Online) U6 - http://dx.doi.org/10.1007/978-3-642-54568-9_12 N1 - 8th International Workshop, DPM 2013, and 6th International Workshop, SETOP 2013, Egham, UK, September 12-13, 2013. Part of the Lecture Notes in Computer Science book series (LNSC,volume 8247) SP - 178 EP - 193 PB - Springer CY - Berlin ER - TY - CHAP A1 - Neumann, Tobias A1 - Ferrein, Alexander A1 - Kallweit, Stephan A1 - Scholl, Ingrid T1 - Towards a mobile mapping robot for underground mines T2 - 7th Conference of Robotics and Mechatronics : RobMech 2014 : 27th and 28th Nov. 2014, Cape Town Y1 - 2014 SP - 1 EP - 6 ER - TY - CHAP A1 - Niedermeier, H. A1 - Clemens, J. A1 - Kowalski, Julia A1 - Macht, S. A1 - Heinen, D. A1 - Hoffmann, R. A1 - Linder, Peter T1 - Navigation system for a research ice probe for antarctic glaciers T2 - IEEE/ION Position, Location and Navigation Symposium (PLANS) ; 5-8 May 2014, Monterey, Calif. Y1 - 2014 SN - 978-1-4799-3319-8 SP - 959 EP - 975 PB - IEEE CY - Piscataway, NJ ER - TY - CHAP A1 - Niemüller, Tim A1 - Ewert, Daniel A1 - Reuter, Sebastian A1 - Ferrein, Alexander A1 - Jeschke, Sabina A1 - Lakemeyer, Gerhard T1 - RoboCup logistics league sponsored by festo: A competitive factory automation testbed T2 - RoboCup 2013: Robot World Cup XVII : Eindhoven; Netherlands; 1 July 2013 through 1 July 2013. (Lecture notes in computer science ; 8371) N2 - A new trend in automation is to deploy so-called cyber-physical systems (CPS) which combine computation with physical processes. The novel RoboCup Logistics League Sponsored by Festo (LLSF) aims at such CPS logistic scenarios in an automation setting. A team of robots has to produce products from a number of semi-finished products which they have to machine during the game. Different production plans are possible and the robots need to recycle scrap byproducts. This way, the LLSF is a very interesting league offering a number of challenging research questions for planning, coordination, or communication in an application-driven scenario. In this paper, we outline the objectives of the LLSF and present steps for developing the league further towards a benchmark for logistics scenarios for CPS. As a major milestone we present the new automated referee system which helps in governing the game play as well as keeping track of the scored points in a very complex factory scenario. Y1 - 2014 SN - 978-3-662-44467-2 (Print) 978-3-662-44468-9 (Online) SP - 336 EP - 347 PB - Springer CY - Berlin ER - TY - PAT A1 - Nötzold, K. A1 - Bragard, Michael A1 - Fink, K. A1 - Griessel, R. A1 - Wegener, R. T1 - Cascaded H-bridge converter with transformer based cell power balancing in each voltage level : [Patentschrift] Y1 - 2014 N1 - Titel des US-Patents: Bypassed cascaded cell converter : [patent of invention]. - Außerdem veröffentlicht als CN103997231 (A) PB - Europäisches Patentamt / United States Patent and Trademark Office [u.a.] CY - Den Haag / Alexandria, VA ER - TY - JOUR A1 - Oberländer, Jan A1 - Kirchner, Patrick A1 - Boyen, Hans-Gerd A1 - Schöning, Michael Josef T1 - Detection of hydrogen peroxide vapor by use of manganese(IV) oxide as catalyst for calorimetric gas sensors JF - Physica status solidi A: Applications and materials science N2 - In this work, the catalyst manganese(IV) oxide (MnO2), of calorimetric gas sensors (to monitor the sterilization agent vaporized hydrogen peroxide) has been investigated in more detail. Chemical analyses by means of X-ray-induced photoelectron spectroscopy have been performed to unravel the surface chemistry prior and after exposure to hydrogen peroxide vapor at elevated temperature, as applied in the sterilization processes of beverage cartons. The surface characterization reveals a change in oxidation states of the metal oxide catalyst after exposure to hydrogen peroxide. Additionally, a cleaning effect of the catalyst, which itself is attached to the sensor surface by means of a polymer interlayer, could be observed. Y1 - 2014 U6 - http://dx.doi.org/10.1002/pssa.201330359 SN - 1521-396X (E-Journal); 1862-6319 (E-Journal); 0031-8965 (Print); 1862-6300 (Print) VL - 211 IS - 6 SP - 1372 EP - 1376 PB - Wiley-VCH CY - Weinheim ER - TY - CHAP A1 - Oberländer, Jan A1 - Kirchner, Patrick A1 - Keusgen, M. A1 - Schöning, Michael Josef T1 - Flexible polyimide-based calorimetric gas sensors for monitoring hy-drogen peroxide in sterilisation processes of aseptic filling machines T2 - Sensoren und Messsysteme 2014 ; Beiträge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in Nürnberg. (ITG-Fachbericht ; 250) Y1 - 2014 SN - 978-3-8007-3622-5 SP - 1 EP - 4 PB - VDE-Verl. CY - Düsseldorf ER - TY - JOUR A1 - Pasteur, Aline A1 - Tippkötter, Nils A1 - Kampeis, Percy A1 - Ulber, Roland T1 - Optimization of high gradient magnetic separation filter units for the purification of fermentation products JF - IEEE TRANSACTIONS ON MAGNETICS N2 - High gradient magnetic separation (HGMS) has been established since the early 1970s. A more recent application of these systems is the use in bioprocesses. To integrate the HGMS in a fermentation process, it is necessary to optimize the separation matrix with regard to the magnetic separation characteristics and permeability of the non-magnetizable components of the fermentation broth. As part of the work presented here, a combined fluidic and magnetic force finite element model simulation was created using the software COMSOL Multiphysics and compared with separation experiments. Finally, as optimal lattice orientation of the separation matrix, a transversal rhombohedral arrangement was defined. The high suitability of the new filter matrix has been verified by separation experiments. Y1 - 2014 U6 - http://dx.doi.org/10.1109/TMAG.2014.2325535 SN - 0018-9464 N1 - Article Sequence Number: 5000607 INSPEC Accession Number: 14663042 VL - 50 IS - 10 SP - Artikel 5000607 PB - IEEE CY - New York, NY ER - TY - JOUR A1 - Pham, Phu Tinh A1 - Staat, Manfred T1 - FEM-based shakedown analysis of hardening structures JF - Asia Pacific journal on computational engineering N2 - This paper develops a new finite element method (FEM)-based upper bound algorithm for limit and shakedown analysis of hardening structures by a direct plasticity method. The hardening model is a simple two-surface model of plasticity with a fixed bounding surface. The initial yield surface can translate inside the bounding surface, and it is bounded by one of the two equivalent conditions: (1) it always stays inside the bounding surface or (2) its centre cannot move outside the back-stress surface. The algorithm gives an effective tool to analyze the problems with a very high number of degree of freedom. Our numerical results are very close to the analytical solutions and numerical solutions in literature. Y1 - 2014 U6 - http://dx.doi.org/10.1186/2196-1166-1-4 SN - 2196-1166 (E-Journal) IS - 1 SP - Article No. 4 PB - SpringerOpen CY - Berlin ER - TY - CHAP A1 - Pieper, Martin A1 - Schulz, Silvia T1 - Teaching Simulation Methods with COMSOL Multiphysics N2 - This paper describes two courses on simulation methods for graduate students: “Simulation Methods” and “Simulation and Optimization in Virtual Engineering” The courses were planned to teach young engineers how to work with simulation software as well as to understand the necessary mathematical background. As simulation software COMSOL is used. The main philosophy was to combine theory and praxis in a way that motivates the students. In addition “soft skills” should be improved. This was achieved by project work as final examination. As underlying didactical principle the ideas of Bloom’s revised taxonomy were followed. The paper basically focusses on educational aspects, e.g. how to structure the course, plan the exercises, organize the project work and include practical COMSOL examples. KW - COMSOL Multiphysics KW - Optimization module KW - LiveLink for MATLAB KW - Bloom Taxonomy KW - education Y1 - 2014 ER - TY - JOUR A1 - Poghossian, Arshak A1 - Schöning, Michael Josef T1 - Label-free sensing of biomolecules with field-effect devices for clinical applications JF - Electroanalysis N2 - Among the variety of transducer concepts proposed for label-free detection of biomolecules, the semiconductor field-effect device (FED) is one of the most attractive platforms. As medical techniques continue to progress towards diagnostic and therapies based on biomarkers, the ability of FEDs for a label-free, fast and real-time detection of multiple pathogenic and physiologically relevant molecules with high specificity and sensitivity offers very promising prospects for their application in point-of-care and personalized medicine for an early diagnosis and treatment of diseases. The presented paper reviews recent advances and current trends in research and development of different FEDs for label-free, direct electrical detection of charged biomolecules by their intrinsic molecular charge. The authors are mainly focusing on the detection of the DNA hybridization event, antibody-antigen affinity reaction as well as clinically relevant biomolecules such as cardiac and cancer biomarkers. Y1 - 2014 U6 - http://dx.doi.org/10.1002/elan.201400073 SN - 1521-4109 (E-Journal); 1040-0397 (Print) VL - 26 IS - 6 SP - 1197 EP - 1213 PB - Wiley-VCH CY - Weinheim ER - TY - CHAP A1 - Poghossian, Arshak A1 - Weiland, Maryam A1 - Schöning, Michael Josef ED - Lvova, Larisa ED - Kirsanov, Dmitry ED - di Natale, Corrado ED - Legin, Audrey T1 - Nanoplate field-effect capacitors: a new transducer structure for multiparameter (bio-)chemical sensing T2 - Multisensor system for chemical analysis : materials and sensors N2 - An array of electrically isolated nanoplate field-effect silicon-on-insulator (SOI) capacitors as a new transducer structure for multiparameter (bio-)chemical sensing is presented. The proposed approach allows addressable biasing and electrical readout of multiple nanoplate field-effect capacitive (bio-)chemical sensors on the same SOI chip, as well as differential-mode measurements. The realized sensor chip has been applied for pH and penicillin concentration measurements, electrical monitoring of polyelectrolyte multilayer formation, and the label-free electrical detection of consecutive deoxyribonucleic acid (DNA) hybridization and denaturation events. Y1 - 2014 SN - 978-981-4411-15-8 ; 978-981-4411-16-5 U6 - http://dx.doi.org/10.1201/b15491-11 SP - 333 EP - 373 PB - Jenny Stanford Publishing CY - Singapore ET - 1 ER - TY - JOUR A1 - Ratke, Lorenz A1 - Milow, Barbara A1 - Lisinski, Susanne A1 - Hoepfner, Sandra T1 - On an effect of fine ceramic particles on the structure of aerogels JF - Microgravity science and technology Y1 - 2014 U6 - http://dx.doi.org/10.1007/s12217-014-9380-2 SN - 0938-0108 ; 1875-0494 VL - 26 SP - 103 EP - 110 PB - Springer Nature CY - Heidelberg ER - TY - JOUR A1 - Rau, Christoph A1 - Alexopoulos, Spiros A1 - Breitbach, Gerd A1 - Hoffschmidt, Bernhard A1 - Latzke, Markus A1 - Sattler, Johannes, Christoph T1 - Transient simulation of a solar-hybrid tower power plant with open volumetric receiver at the location Barstow JF - Energy procedia : proceedings of the SolarPACES 2013 International Conference N2 - In this work the transient simulations of four hybrid solar tower power plant concepts with open-volumetric receiver technology for a location in Barstow-Daggett, USA, are presented. The open-volumetric receiver uses ambient air as heat transfer fluid and the hybridization is realized with a gas turbine. The Rankine cycle is heated by solar-heated air and/or by the gas turbine's flue gases. The plant can be operated in solar-only, hybrid parallel or combined cycle-only mode as well as in any intermediate load levels where the solar portion can vary between 0 to 100%. The simulated plant is based on the configuration of a solar-hybrid power tower project, which is in planning for a site in Northern Algeria. The meteorological data for Barstow-Daggett was taken from the software meteonorm. The solar power tower simulation tool has been developed in the simulation environment MATLAB/Simulink and is validated. Y1 - 2014 U6 - http://dx.doi.org/10.1016/j.egypro.2014.03.157 SN - 1876-6102 VL - 49 SP - 1481 EP - 1490 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Raue, Markus A1 - Wambach, M. A1 - Glöggler, S. A1 - Grefen, Dana A1 - Kaufmann, R. A1 - Abetz, C. A1 - Georgopanos, P. A1 - Handge, U. A. A1 - Mang, Thomas A1 - Blümich, B. A1 - Abetz, V. T1 - Investigation of historical hard rubber ornaments of Charles Goodyear JF - Macromolecular chemistry and physics Y1 - 2014 SN - 1022-1352 VL - Vol. 215 IS - No. 3 SP - 245 EP - 254 PB - Wiley-VCH CY - Weinheim ER - TY - THES A1 - Reyes Ochoa, Leonel T1 - Engineering aspects of a parabolic trough collector field with direct steam generation and an organic rankine cycle Y1 - 2014 N1 - Aachen, Fachhochsch., Masterarbeit, 2014 PB - Fachhochschule Aachen CY - Aachen ER - TY - JOUR A1 - Riedel, Marc A1 - Kartchemnik, Julia A1 - Schöning, Michael Josef A1 - Lisdat, Fred T1 - Impedimetric DNA detection – steps forward to sensorial application JF - Analytical chemistry N2 - This study describes a label-free impedimetric sensor based on short ssDNA recognition elements for the detection of hybridization events. We concentrate on the elucidation of the influence of target length and recognition sequence position on the sensorial performance. The impedimetric measurements are performed in the presence of the redox system ferri-/ferrocyanide and show an increase in charge transfer resistance upon hybridization of ssDNA to the sensor surface. Investigations on the impedimetric signal stability demonstrate a clear influence of the buffers used during the sensor preparation and the choice of the passivating mercaptoalcanol compound. A stable sensor system has been developed, enabling a reproducible detection of 25mer target DNA in the low nanomolar range. After hybridization, a sensor regeneration can be reached with deionized water by adjustment of effective convection conditions, ensuring a sensor reusability. By investigations of longer targets with overhangs exposed to the solution, we can demonstrate applicability of the impedimetric detection for longer ssDNA. However, a decreasing charge transfer resistance change (ΔRct) is found by extending the overhang. As a strategy to increase the impedance change for longer target strands, the position of the recognition sequence can be designed in a way that a small overhang is exposed to the electrode surface. This is found to result in an increase in the relative Rct change. These results suggest that DNA and consequently negative charge near the electrode possess a larger impact on the impedimetric signal than DNA further away. Y1 - 2014 U6 - http://dx.doi.org/10.1021/ac501800q SN - 1520-6882 (E-Journal); 0003-2700 (Print); 0096-4484 (Print) VL - 86 (2014) IS - 15 SP - 7867 EP - 7874 PB - ACS Publications CY - Columbus ER - TY - CHAP A1 - Ritz, Thomas A1 - Izquierdo Tello, César A1 - Damm, Sebastian T1 - Connecting a pedelec to the cloud as basis for gamification in multi modal mobility planning T2 - MobileCloud 2014 : 2nd IEEE International Conference on Mobile Cloud Computing, Services, and Engineering Oxford, United Kingdom 7-10 April 2014 Y1 - 2014 SN - 978-1-4799-2504-9 U6 - http://dx.doi.org/10.1109/MobileCloud.2014.25 SP - 101 EP - 108 PB - IEEE Service Center CY - Piscataway, NJ ER -