TY  - JOUR
A1  - Wilson, Ian D.
A1  - Wilson, Claire E.
A1  - Scheer, Nico
A1  - Dickie, A.P.
A1  - Schreiter, K.
A1  - Wilson, E. M.
A1  - Riley, R. J.
A1  - Wehr, R.
A1  - Bial, J.
T1  - The Pharmacokinetics and Metabolism of Lumiracoxib in Chimeric Humanized and Murinized FRG Mice
JF  - Biochemical pharmacology
Y1  - 2017
U6  - http://dx.doi.org/10.1016/j.bcp.2017.03.015
SN  - 1873-2968
VL  - Volume 135
SP  - 139
EP  - 150
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Wilson, C. E.
A1  - Dickie, A. P.
A1  - Schreiter, K.
A1  - Wehr, R.
A1  - Wilson, E. M.
A1  - Bial, J.
A1  - Scheer, Nico
A1  - Wilson, I. D.
A1  - Riley, R. J.
T1  - The pharmacokinetics and metabolism of diclofenac in chimeric humanized and murinized FRG mice
JF  - Archives of Toxicology
N2  - The pharmacokinetics of diclofenac were investigated following single oral doses of 10 mg/kg to chimeric liver humanized and murinized FRG and C57BL/6 mice. In addition, the metabolism and excretion were investigated in chimeric liver humanized and murinized FRG mice. Diclofenac reached maximum blood concentrations of 2.43 ± 0.9 µg/mL (n = 3) at 0.25 h post-dose with an AUCinf of 3.67 µg h/mL and an effective half-life of 0.86 h (n = 2). In the murinized animals, maximum blood concentrations were determined as 3.86 ± 2.31 µg/mL at 0.25 h post-dose with an AUCinf of 4.94 ± 2.93 µg h/mL and a half-life of 0.52 ± 0.03 h (n = 3). In C57BL/6J mice, mean peak blood concentrations of 2.31 ± 0.53 µg/mL were seen 0.25 h post-dose with a mean AUCinf of 2.10 ± 0.49 µg h/mL and a half-life of 0.51 ± 0.49 h (n = 3). Analysis of blood indicated only trace quantities of drug-related material in chimeric humanized and murinized FRG mice. Metabolic profiling of urine, bile and faecal extracts revealed a complex pattern of metabolites for both humanized and murinized animals with, in addition to unchanged parent drug, a variety of hydroxylated and conjugated metabolites detected. The profiles in humanized mice were different to those of both murinized and wild-type animals, e.g., a higher proportion of the dose was detected in the form of acyl glucuronide metabolites and much reduced amounts as taurine conjugates. Comparison of the metabolic profiles obtained from the present study with previously published data from C57BL/6J mice and humans revealed a greater, though not complete, match between chimeric humanized mice and humans, such that the liver humanized FRG model may represent a model for assessing the biotransformation of such compounds in humans.
Y1  - 2018
U6  - http://dx.doi.org/10.1007/s00204-018-2212-1
SN  - 1432-0738
VL  - 92
IS  - 6
SP  - 1953
EP  - 1967
PB  - Springer
ER  - 
TY  - JOUR
A1  - Hagemann, Hans-Jürgen
A1  - Lade, H.
A1  - Warnier, J.
A1  - Wiechert, D. U.
T1  - The performance of Depressed-Cladding Single-Mode Fibres with Different b/a Ratios. Hagemann, H.-J.; Lade, H.; Warnier, J.; Wiechert, D. U.
JF  - Journal of Lightwave Technology (J-LT) / Institute of Electrical and Electronics Engineers (IEEE). 9 (1991), H. 6
Y1  - 1991
SN  - 0733-8724
SP  - 689
EP  - 694
ER  - 
TY  - JOUR
A1  - Kotter, Michael
A1  - Riekert, Lothar
A1  - Weyland, Friedrich
T1  - The performance of base metal oxides on ceramic carriers as catalysts for air pollution control
JF  - International chemical engineering. 25 (1985), H. 3
Y1  - 1985
SN  - 0020-6318
SP  - 418
EP  - 427
ER  - 
TY  - JOUR
A1  - Müller-Veggian, Mattea
A1  - Beuscher, H.
A1  - Gono, Y.
A1  - Lieder, R. M.
T1  - The orange-ß-spectrometer at the external beam of the cyclotron
JF  - Annual report 1976 / Institut für Kernphysik Kernforschungsanlage Jülich / Ed. board: A. Fäßler ...
Y1  - 1977
SP  - 124
PB  - Kernforschungsanlage
CY  - Jülich
ER  - 
TY  - JOUR
A1  - Müller-Veggian, Mattea
A1  - Turek, M.
A1  - Colautti, P.
T1  - The new Twin mini TEPC: an advanced tool for Boron Neutron Capture Therapy
JF  - Annual report / Istituto Nazionale di Fisica Nucleare, LNL, Laboratori Nazionali di Legnaro. 2004 (2005)
Y1  - 2005
SN  - 88-7337-008-X
N1  - LNL-INFN(REP)-204/2005
SP  - 244
EP  - 245
ER  - 
TY  - JOUR
A1  - Scherer, Ulrich W.
A1  - Heßberger, F. P.
A1  - Gäggeler, H. W.
A1  - Armbruster, P.
T1  - The New Nuclide 225U / F.P. Heßberger, H. Gäggeler, P. Armbruster, W. Brüchle, H. Folger, S. Hofmann, D. Jost, J.V. Kratz, M.E. Leino, G. Münzenberg, V. Ninov, M. Schädel, U.W. Scherer, K. Sümmerer, A. Türler, D. Ackerman
JF  - Zeitschrift für Physik A Hadrons and Nuclei. 333 (1989), H. 1
Y1  - 1989
SN  - 0939-7922
SP  - 111
EP  - 112
ER  - 
TY  - JOUR
A1  - Müller-Veggian, Mattea
A1  - Moro, D.
A1  - Ferreti, A.
A1  - Colautti, P.
T1  - The new articulated twin mini TEPC
JF  - Annual Report  2006 / Istituto Nazionale di Fisica Nucleare <Frascati> / Laboratori Nazionali <Legnaro>
Y1  - 2006
SP  - 273
CY  - Legnaro
ER  - 
TY  - JOUR
A1  - Taylor, J. G.
A1  - Schmitz, N.
A1  - Ziemons, Karl
A1  - Grosse-Ruyken, M.-L.
A1  - Gruber, O.
A1  - Müller-Gärtner, H.-W.
A1  - Shah, N. J.
T1  - The network of brain areas involved in the motion aftereffect
JF  - Neuroimage
N2  - A network of brain areas is expected to be involved in supporting the motion aftereffect. The most active components of this network were determined by means of an fMRI study of nine subjects exposed to a visual stimulus of moving bars producing the effect. Across the subjects, common areas were identified during various stages of the effect, as well as networks of areas specific to a single stage. In addition to the well-known motion-sensitive area MT the prefrontal brain areas BA44 and 47 and the cingulate gyrus, as well as posterior sites such as BA37 and BA40, were important components during the period of the motion aftereffect experience. They appear to be involved in control circuitry for selecting which of a number of processing styles is appropriate. The experimental fMRI results of the activation levels and their time courses for the various areas are explored. Correlation analysis shows that there are effectively two separate and weakly coupled networks involved in the total process. Implications of the results for awareness of the effect itself are briefly considered in the final discussion.
Y1  - 2000
SN  - 1053-8119
VL  - 11
IS  - 4
SP  - 257
EP  - 270
ER  - 
TY  - JOUR
A1  - Hautzel, H.
A1  - Taylor, J. G.
A1  - Krause, B. J.
A1  - Schmitz, N.
A1  - Tellmann, L.
A1  - Ziemons, Karl
A1  - Shah, N. J.
A1  - Herzog, H.
A1  - Müller-Gärtner, H.-W.
T1  - The motion aftereffect: more than area V5/MT? Evidence from 15O-butanol PET studies
JF  - Brain Research
N2  - The motion aftereffect is a perceptual phenomenon which has been extensively investigated both psychologically and physiologically. Neuroimaging techniques have recently demonstrated that area V5/MT is activated during the perception of this illusion. The aim of this study was to test the hypothesis if a more broadly distributed network of brain regions subserves the motion aftereffect. To identify the neuronal structures involved in the perception of the motion aftereffect, regional cerebral blood flow (rCBF) measurements with positron emission tomography were performed in six normal volunteers. Data were analysed using SPM96. The motion-sensitive visual areas including area V5/MT were activated in both hemispheres. Additionally, the lateral parietal cortex bilaterally, the right dorsolateral prefrontal cortex, the anterior cingulate cortex and the left cerebellum showed significant increases in rCBF values during the experience of the waterfall illusion. In a further reference condition with identical attentional demand but no perception of a motion aftereffect elevated rCBF were found in these regions as well. In conclusion, our findings support the notion that the perceptual illusion of motion arises exclusively in the motion-sensitive visual area V5/MT. In addition, a more widespread network of brain regions including the prefrontal and parietal cortex is activated during the waterfall illusion which represents a non-motion aftereffect-specific subset of brain areas but is involved in more basic attentional processing and cognition.
Y1  - 2001
SN  - 0006-8993
VL  - 892
IS  - 2
SP  - 281
EP  - 292
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Schmid-Schönbein, H.
T1  - The microscope-photometrical-monolayer-technique- a new principle for analyzing the distribution of rheological responses in pathological and experimentally modified red cell populations. Artmann, Gerhard Michael; Schmid-Schönbein, H.
JF  - Microcirculation, an update : proceedings of the Fourth World Congress for Microcirculation, Tokyo, Japan, July 26-30, 1987
Y1  - 1987
SN  - 0444809511
N1  - World Congress for Microcirculation (4, 1987, Tokyo;); International congress series ; 755
SP  - 475
EP  - 477
PB  - Excerpta Medica
CY  - Amsterdam [u.a.]
ER  - 
TY  - JOUR
A1  - Wittmann, Klaus
A1  - Schmidt, H. P.
A1  - Padeken, D.
A1  - Hildmann, B.
T1  - The Microgravity User Support Centre (MUSC)
JF  - ESA SP. 277 (1988)
Y1  - 1988
SN  - 0379-6566
N1  - Proceedings of the International Symposium on Europe in Space--the Manned Space System : 25-29 April 1988, Strasbourg, France  David, Valerie ; Longdon, Norman [ed]
SP  - 525
ER  - 
TY  - JOUR
A1  - Wittmann, Klaus
T1  - The microgravity User Support Centre
JF  - Space Technology - Industrial and Commercial Applications. 13 (1993), H. 2
Y1  - 1993
SN  - 0892-9270
SP  - 121
EP  - 124
ER  - 
TY  - JOUR
A1  - Janz, Norbert
A1  - Ebling, Günther
A1  - Gottschalk, Sandra
A1  - Niggemann, Hiltrud
T1  - The Mannheim Innovation Panels (MIP and MIP-S) of the Centre for European Economic Research (ZEW) / Janz, N., G. Ebling, S. Gottschalk und H. Niggemann
JF  - Schmollers Jahrbuch : Zeitschrift für Wirtschafts- und Sozialwissenschaften ; journal of applied social science studies. 121 (2001)
Y1  - 2001
SN  - 0342-1783
SP  - 123
EP  - 129
ER  - 
TY  - JOUR
A1  - Kern, Alexander
A1  - Lang, U.
A1  - Wiesinger, J.
A1  - Zischank, Wolfgang J.
T1  - The longitudinal voltage of cable tubes with a screening mesh caused by partial lightning currents
JF  - Proceedings / Sixth International Symposium on High Voltage Engineering : 28. August - 1. September, 1989, Westin Canal Place Hotel, New Orleans, Louisiana, USA
Y1  - 1989
N1  - International Symposium on High Voltage Engineering <6, 1989, New Orleans, La.>
PB  - Mississippi State University
CY  - Mississippi State, Miss.
ER  - 
TY  - JOUR
A1  - Yoshinobu, T.
A1  - Iwasaki, H.
A1  - Ui, Y.
A1  - Furuichi, K.
A1  - Ermelenko, Y.
A1  - Mourzina, Y.
A1  - Wagner, Torsten
A1  - Näther, Niko
A1  - Schöning, Michael Josef
T1  - The light-addressable potentiometric sensor for multi-ion sensing and imaging
JF  - Methods. 37 (2005), H. 1
Y1  - 2005
SN  - 1046-2023
SP  - 99
EP  - 102
ER  - 
TY  - JOUR
A1  - Baumann, Marcus
A1  - Rousseau, V.
A1  - Vaulot, D.
A1  - Casotti, R.
T1  - The life cycle of Phaeocystis (Prymnesiophycae): evidence and hypotheses / Rousseau, V. ; Vaulot, D. ; Casotti, R. ; Cariou, V. ; Lenz, J. ; Gunkel, J. ; Baumann, M.
JF  - Journal of Marine Systems. 5 (1994), H. 1
Y1  - 1994
SN  - 0924-7963
SP  - 23
EP  - 39
ER  - 
TY  - JOUR
A1  - Kleefeld, A.
A1  - Reißel, Martin
T1  - The Levenberg–Marquardt method applied to a parameter estimation problem arising from electrical resistivity tomography
JF  - Applied Mathematics and Computation
Y1  - 2011
SN  - 0096-3003
VL  - 217
IS  - 9
SP  - 4490
EP  - 4501
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Baumann, Marcus
A1  - Goeyens, L.
A1  - Tréguer, P.
A1  - Baeyens, W.
T1  - The leading role of ammonium in the nitrogen uptake regime of Southern Ocean marginal ice zones / Goeyens, L. ; Tréguer, P. ; Baumann, M.E.M. ; Baeyens, W. ; Dehairs, F.
JF  - Journal of Marine Systems. 6 (1995), H. 4
Y1  - 1995
SN  - 0924-7963
SP  - 345
EP  - 361
ER  - 
TY  - JOUR
A1  - Hanrath, Wilhelm
A1  - Plesken, Wilhelm
T1  - The lattices of six-dimensional euclidean space
JF  - Mathematics of computation. 43 (1984), H. 168
Y1  - 1984
SN  - 0025-5718
SP  - 573
EP  - 587
ER  - 
TY  - JOUR
A1  - Faßbender, Heinz
A1  - Bühler, Gerhard
T1  - The join of a geographical situation display system and a platform independent C2 information system
JF  - Proceedings of the 2000 Command and Control Research and Technology Symposium, Juni 2000, Monterey, USA
Y1  - 2000
SP  - 1
EP  - 7
ER  - 
TY  - JOUR
A1  - Ferrein, Alexander
A1  - Steinbauer, Gerald
T1  - The Interplay of Aldebaran and RoboCup
JF  - KI - Künstliche Intelligenz
Y1  - 2016
U6  - http://dx.doi.org/10.1007/s13218-016-0440-1
SN  - 1610-1987
VL  - 30
IS  - 3-4
SP  - 325
EP  - 326
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Lauth, Jakob
A1  - Solomun, T.
A1  - Hirschwald, W.
A1  - Christmann, K.
T1  - The interaction of carbon monoxide with a ruthenium(1010) surface
JF  - Surface Science. 210 (1989), H. 1-2
Y1  - 1989
SN  - 0039-6028
SP  - 201
EP  - 224
ER  - 
TY  - JOUR
A1  - Lauth, Jakob
A1  - Solomun, T.
A1  - Hirschwald, W.
A1  - Christmann, K.
T1  - The interaction of carbon monoxide with a ruthenium(1010) surface
JF  - Surface Science Letters. 210 (1989), H. 1-2
Y1  - 1989
SN  - 0167-2584
SP  - A74
EP  - A75
ER  - 
TY  - JOUR
A1  - Bragard, Michael
A1  - Conrad, M.
A1  - van Hoek, H.
A1  - De Doncker, R. W.
T1  - The integrated emitter turn-off thyristor (IETO) : an innovative thyristor-based high power semiconductor device using MOS assisted turn-off
JF  - IEEE transactions on industry applications
Y1  - 2011
U6  - http://dx.doi.org/10.1109/TIA.2011.2161432
SN  - 0093-9994
VL  - 47
IS  - 5
SP  - 2175
EP  - 2182
PB  - IEEE
CY  - New York
ER  - 
TY  - JOUR
A1  - Herrmann, Ulf
A1  - Lippke, F.
T1  - The influence of transients on the design of DSG solar fields
JF  - Journal de Physique IV : proceedings
Y1  - 1999
SN  - 2-86883-402-7
U6  - http://dx.doi.org/10.1051/jp4:1999377
SN  - 1764-7177 (Online)
SN  - 1155-4339 (Print)
VL  - 9
IS  - PR3
SP  - 489
EP  - 494
ER  - 
TY  - JOUR
A1  - Klein, Michel
A1  - Butenweg, Christoph
A1  - Klinkel, Sven
T1  - The Influence of Soil-Structure-Interaction on the Fatigue Analysis in the Foundation Design of Onshore Wind Turbines
JF  - Procedia Engineering
Y1  - 2017
U6  - http://dx.doi.org/10.1016/j.proeng.2017.09.325
SN  - 1877-7058
VL  - 199
SP  - 3218
EP  - 3223
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Baumann, Marcus
A1  - Brandini, Frederico
A1  - Staubes, Regina
T1  - The influence of light and temperature on carbonspecific DMS release by cultures of Phaeocystis antarctica and three antarctic diatoms / Baumann, Marcus E.M. ; Brandini, Frederico ; Staubes, Regina
JF  - Marine Chemistry. 45 (1994), H. 1-2
Y1  - 1994
SN  - 0304-4203
SP  - 129
EP  - 136
ER  - 
TY  - JOUR
A1  - Kotter, Michael
A1  - Riekert, L.
T1  - The influence of impregnation, drying and activation on the activity and distribution of CuO on &#945;-Alumina
JF  - Preparation of Catalysts II : scientific bases for the preparation of heterogeneous catalysts ; Proceedings of the Second International Symposium, Louvain-la-Neuve, September 4-7, 1978 / Eds.: B. Delmon ... - (Studies in surface science and catalysis ; 3)
Y1  - 1979
SN  - 0-444-41733-8
N1  - International Symposium on the Scientific Bases for the Preparation of Heterogeneous Catalysts <2, 1978, Louvain-la-Neuve>
SP  - 51
EP  - 63
PB  - Elsevier
CY  - Amsterdam [u.a.]
ER  - 
TY  - JOUR
A1  - Behbahani, Mehdi
A1  - Probst, M.
A1  - Mai, A.
A1  - Tran, L.
A1  - Vonderstein, K.
A1  - Keschenau, P.
A1  - Linde, T.
A1  - Steinseifer, U.
A1  - Behr, M.
A1  - Mottaghy, K.
T1  - The influence of high shear on thrombosis and hemolysis in artificial organs
JF  - Artificial Organs
Y1  - 2010
SN  - 0391-3988
N1  - Special Issue: SI ; Meeting abstract
VL  - 33
IS  - 7
SP  - 426
EP  - 426
ER  - 
TY  - JOUR
A1  - Biselli, Manfred
A1  - Thömmes, J.
A1  - Gätgens, J.
A1  - Runstadler, P. W.
T1  - The influence of dissolved oxygen tension on the metabolic activity of an immobilized hybridoma population / Thömmes, J. ; Gätgens, J. ; Biselli, M. ; Runstadler, P.W. ; Wandrey, C.
JF  - Cytotechnology . 13 (1993), H. 1
Y1  - 1993
SN  - 0920-9069
SP  - 29
EP  - 39
ER  - 
TY  - JOUR
A1  - Panc, Nicolae
A1  - Contiu, Glad
A1  - Bocanet, Vlad
A1  - Thurn, Laura
A1  - Sabau, Emilia
T1  - The influence of cutting technology on surface wear hardness
JF  - Academic Journal of Manufacturing Engineering
Y1  - 2019
SN  - 1583-7904
VL  - 17
IS  - 3
SP  - 205
EP  - 210
ER  - 
TY  - JOUR
A1  - Hagemann, Hans-Jürgen
A1  - Stumpe, R.
A1  - Wagner, D.
A1  - Bäuerle, D.
T1  - The influence of contact effects on the dielectric behavior of diffuse phase transitions. Stumpe, R.; Wagner, D.; Bäuerle, D.; Hagemann, H. J.
JF  - Ferroelectrics : the international journal devoted to the theoretical, experimental, and applied aspects of ferroelectrics and related materials / Letters section. 4 (1985)
Y1  - 1985
SN  - 0731-5171
SP  - 143
EP  - 147
ER  - 
TY  - JOUR
A1  - Kämper, Klaus-Peter
A1  - Schmitt, W.
A1  - Güntherodt, G.
T1  - The influence of adsorbates on the spin-resolved photoemission of Ni(110). Schmitt, W.; Kämper, K.-P.; Güntherodt, G.
JF  - Surface Science. 189/190 (1987)
Y1  - 1987
SN  - 0039-6028
N1  - Proceedings of the Ninth European Conference on Surface Science
SP  - 741
EP  - 507
ER  - 
TY  - JOUR
A1  - Heuermann, Holger
A1  - Schiek, Burkhard
T1  - The In-Fixture Calibration Procedure Line-Network-Network-LNN
JF  - Conference proceedings : monday 6th to thursday 9th september 1993, Palacio de Congresos, Madrid, Spain ; [the international conference and exhibition designed for the Microwave Community]
Y1  - 1992
SN  - 0-946821-23-2
N1  - European Microwave Conference <23, 1993, Madrid>
SP  - 500
EP  - 505
PB  - Reed Exhibition Companies
CY  - Tunbridge Wells
ER  - 
TY  - JOUR
A1  - Scherer, Ulrich W.
A1  - Brüchle, W.
A1  - Schädel, M.
A1  - Kratz, J. V.
T1  - The Hydration Enthalpies of Md3+ and Lr3+ / W. Brüchle, M. Schädel, U.W. Scherer, J.V. Kratz, K.E. Gregorich, D. Lee, M. Nurmia, R.M. Chasteler, H.L. Hall, R.A. Henderson, D.C. Hoffman
JF  - Inorganica Chimica Acta. 146 (1988), H. 2
Y1  - 1988
SN  - 0020-1693
SP  - 267
EP  - 276
ER  - 
TY  - JOUR
A1  - Ermelenko, Y.
A1  - Yoshinobu, T.
A1  - Mourzina, Y.
A1  - Schöning, Michael Josef
A1  - Vlasov, Y.
A1  - Iwasaki, H.
T1  - The hybrid K+/Ca2+ sensor based on laser scanned silicon transducer for multi-component analysis
JF  - Proceedings of ICAS 2001, IUPAC [3rd] International Congress on Analytical Sciences 2001 : August 6 - 10, 2001, Waseda University, Tokyo
Y1  - 2002
N1  - International Congress on Analytical Sciences <2001, Tokyo> ; International Union of Pure and Applied Chemistry. Pure and applied chemistry ; 73,10. ; Analytical sciences ; 17.2001, special issue
SP  - i777
EP  - i780
PB  - Japan Society for Analytical Chemistry
CY  - Tokyo
ER  - 
TY  - JOUR
A1  - Glaser, Stefan
A1  - Lubitz, Sandra
A1  - Loveland, Kate L.
A1  - Ohbo, Kazu
A1  - Robb, Lorraine
A1  - Schwenk, Frieder
A1  - Seibler, Jost
A1  - Roellig, Daniela
A1  - Kranz, Andrea
A1  - Anastassiadis, Konstantinos
A1  - Stewart, A. Francis
T1  - The histone 3 lysine 4 methyltransferase, Mll2, is only required briefly in development and spermatogenesis
JF  - Epigenetics & Chromatin
Y1  - 2009
U6  - http://dx.doi.org/10.1186/1756-8935-2-5
SN  - 1756-8935
VL  - 2
IS  - 5
SP  - 1
EP  - 16
ER  - 
TY  - JOUR
A1  - Kern, Alexander
T1  - The heating of metal sheets caused by direct lightning strikes-model and measurement
JF  - 20th ICPL / International Conference on Lightning Protection, Congress-Center Casino Interlaken, Switzerland, September 24-28, 1990 = Internationale Blitzschutzkonferenz, Congress-Center Casino Interlaken, Schweiz, 24.-28. September 1990
Y1  - 1990
N1  - International Conference on Lightning Protection <20, 1990, Interlaken> ; Internationale Blitzschutzkonferenz <20, 1990, Interlaken>
PB  - Schweizerischer Elektrotechnischer Verein
CY  - [Zürich]
ER  - 
TY  - JOUR
A1  - Polen, T.
A1  - Krämer, Marco
A1  - Bongaerts, Johannes
A1  - Wubbolts, Marcel
A1  - Wendisch, V. F.
T1  - The global gene expression response of Escherichia coli to L-phenylalanine
JF  - Journal of biotechnology
Y1  - 2005
SN  - 1873-4863 (E-Journal); 0168-1656 (Print)
VL  - Vol. 115
IS  - Iss. 3
SP  - 221
EP  - 237
ER  - 
TY  - JOUR
A1  - Mottaghy, Darius
A1  - Pechnig, Renate
A1  - Vogt, Christian
T1  - The geothermal project Den Haag: 3D numerical models for temperature prediction and reservoir simulation
JF  - Geothermics
N2  - The proposed Den Haag Zuidwest district heating system of the city of The Hague consists of a deep doublet in a Jurassic sandstone layer that is designed for a production temperature of 75 °C and a reinjection temperature of 40 °C at a flow rate of 150 m3 h−1. The prediction of reservoir temperature and production behavior is crucial for success of the proposed geothermal doublet. This work presents the results of a study of the important geothermal and geohydrological issues for the doublet design. In the first phase of the study, the influences of the three-dimensional (3D) structures of anticlines and synclines on the temperature field were examined. A comprehensive petrophysical investigation was performed to build a large scale 3D-model of the reservoir. Several bottomhole temperatures (BHTs), as well as petrophysical logs were used to calibrate the model using thermal conductivity measurements on 50 samples from boreholes in different lithological units in the study area. Profiles and cross sections extracted from the calculated temperature field were used to study the temperature in the surrounding areas of the planned doublet. In the second phase of the project, a detailed 3D numerical reservoir model was set up, with the aim of predicting the evolution of the producer and injector temperatures, and the extent of the cooled area around the injector. The temperature model from the first phase provided the boundary conditions for the reservoir model. Hydraulic parameters for the target horizons, such as porosity and permeability, were taken from data available from the nearby exploration wells. The simulation results are encouraging as no significant thermal breakthrough is predicted. For the originally planned location of the producer, the extracted water temperature is predicted to be around 79 °C, with an almost negligible cooling in the first 50 years of production. When the producer is located shallower parts of the reservoir, the yield water temperatures is lower, starting at ≈76 °C and decreasing to ≈74 °C after 50 years of operation. This comparatively larger decrease in temperature with time is caused by the structural feature of the reservoir, namely a higher dip causes the cooler water to easily move downward. In view of the poor reservoir data, the reservoir simulation model is constructed to allow iterative updates using data assimilation during planned drilling, testing, and production phases. Measurements during an 8 h pumping test carried out in late 2010 suggest that a flow rate of 150 m3 h−1 is achievable. Fluid temperatures of 76.5 °C were measured, which is very close to the predicted value.
Y1  - 2011
U6  - http://dx.doi.org/10.1016/j.geothermics.2011.07.001
SN  - 0375-6505
VL  - 40
IS  - 3
SP  - 199
EP  - 210
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Lyons, W. Berry
A1  - Mikucki, Jill A.
A1  - German, Laura A.
A1  - Welch, Kathleen A.
A1  - Welch, Susan A.
A1  - Gardener, Christopher B.
A1  - Tulaczyk, Slawek M.
A1  - Pettit, Erin C.
A1  - Kowalski, Julia
A1  - Dachwald, Bernd
T1  - The Geochemistry of Englacial Brine from Taylor Glacier, Antarctica
JF  - Journal of Geophysical Research: Biogeosciences
Y1  - 2019
U6  - http://dx.doi.org/10.1029/2018JG004411
SN  - 2169-8961
PB  - Wiley
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Laack, Walter van
T1  - The genetic code should be seen as a positioning code
JF  - British journal of arts and social sciences. Vol. 14 (2013), No. 1
Y1  - 2013
SN  - 2046-9578
SP  - 93
EP  - 97
ER  - 
TY  - JOUR
A1  - Riemer, A.
A1  - Schroth, P.
A1  - Schütz, S.
A1  - Hummel, Hans E.
A1  - Lüth, H.
A1  - Kohl, C.-D.
A1  - Schöning, Michael Josef
T1  - The future of fire detection: Biological sensors? – Die Zukunft der Brandgassensorik: Biologische Sensoren?
JF  - Gassensorik in der Brandmeldetechnik : [VdS-Fachtagung, am 15. und 16. November 2000 in Köln] = Gas sensors for fire detection / VdS Schadenverhütung
Y1  - 2000
N1  - Fachtagung Gassensorik in der Brandmeldetechnik ; (2000, Köln)
SP  - 1
EP  - 7
PB  - VdS Schadenverhütung
CY  - Köln
ER  - 
TY  - JOUR
A1  - Selmer, Thorsten
A1  - Hallmann, Armin
A1  - Schmidt, Bernhard
A1  - Sumper, Manfred
T1  - The Evolutionary Conservation of a Novel Protein Modification, the Conversion of Cysteine to Serinesemialdehyde in Arylsulfatase from Volvox carteri / Selmer, Thorsten ; Hallmann, Armin ; Schmidt, Bernhard ; Sumper, Manfred ; Figura, Kurt von
JF  - European Journal of Biochemistry. 238 (1996), H. 2
Y1  - 1996
SN  - 0014-2956
SP  - 341
EP  - 345
ER  - 
TY  - JOUR
A1  - Blome, Hans-Joachim
A1  - Wilson, Thomas L.
T1  - The entangled Universe
JF  - Relativistic Astrophysics and Cosmology, Proceedings of the 13th Course of the International School of Cosmic Ray Astrophysics, held in Erice, Italy, 2-14 June 2002 / edited by Maurice M. Shapiro ... [et al.]
Y1  - 2004
SN  - 981-238-727-7
SP  - 23
EP  - 38
PB  - World Scientific Publishing
CY  - New Jersey, NJ
ER  - 
TY  - JOUR
A1  - Digel, Ilya
A1  - Temiz Artmann, Aysegül
T1  - The emperor's new body : seeking for a blueprint of limb regeneration in humans
JF  - Stem cell engineering : principles and applications / Gerhard M. Artmann ... eds.
Y1  - 2011
SN  - 978-3-642-11864-7
SP  - 3
EP  - 37
PB  - Springer
CY  - Berlin [u.a.]
ER  - 
TY  - JOUR
A1  - Temiz Artmann, Aysegül
A1  - Cavdar, C.
A1  - Yenicerioglu, Y.
A1  - Caliskan, S.
T1  - The effects of intravenous iron treatment on oxidant stress and erythrocyte deformability in haemodialysis patients. Cavdar, C.; Temiz, A.; Yenicerioglu, Y.; Caliskan, S.; Celik, A.; Sifil, A.; Onvural, B.; Camsari, T.
JF  - Scandinavian Journal of Urology and Nephrology. 37 (2003), H. 1
Y1  - 2003
SN  - 0036-5599
SP  - 77
EP  - 82
ER  - 
TY  - JOUR
A1  - Temiz Artmann, Aysegül
A1  - Yolcuoglu, B.
A1  - Onal, M. A.
A1  - Sipahi, O.
T1  - The effect of skin transplantation on tumour growth in mice. Yolcuoglu, B.; Onal, M. A.; Sipahi, O.; Temiz, A.; Pekcetin, C.; Acikgöz, O.; Kar,  H.; Güre A.
JF  - The American Journal of Surgery. 178 (1999), H. 4
Y1  - 1999
SN  - 0002-9610
SP  - 329
EP  - 330
ER  - 
TY  - JOUR
A1  - Kern, Alexander
A1  - Zischank, Wolfgang J.
T1  - The effect of parallel wires on the longitudinal voltage drop along shielded cables
JF  - Conference proceedings : 21st International Conference on Lightning Protection, Berlin Congress Center (BCC) Germany, September 22 - 25, 1992 = 21. Internationale Blitzschutzkonferenz / [proceedings ed. staff: J. Pilling ...]
Y1  - 1992
SN  - 3-8007-1885-5
N1  - International Conference on Lightning Protection <21, 1992, Berlin> ; ICLP <21, 1992, Berlin>
PB  - VDE-Verl.
CY  - Berlin [u.a.]
ER  -