TY - JOUR A1 - Zerlin, Kay A1 - Kasischke, Nicole A1 - Digel, Ilya A1 - Maggakis-Kelemen, Christina A1 - Temiz Artmann, Aysegül A1 - Porst, Dariusz A1 - Kayser, Peter A1 - Linder, Peter A1 - Artmann, Gerhard T1 - Structural transition temperature of hemoglobins correlates with species’ body temperature JF - European Biophysics Journal. 37 (2007), H. 1 Y1 - 2007 SN - 1432-1017 SP - 1 EP - 10 ER - TY - JOUR A1 - Zerlin, Kay A1 - Digel, Ilya A1 - Stadler, Andreas M. A1 - Büldt, Georg A1 - Zaccai, Guiseppe A1 - Artmann, Gerhard T1 - Dynamics and interactions of hemoglobin in human red blood cells and concentrated hemoglobin solutions JF - Regenerative medicine. 2 (2007), H. 5 Y1 - 2007 SN - 1746-0751 N1 - Proceedings of the 3rd World Congress on Regenerative Medicine. October 18-20, 2007. Leipzig, Germany SP - 573 EP - 573 ER - TY - JOUR A1 - Wittmann, Klaus A1 - Bibring, J.-P. A1 - Rosenbauer, H. A1 - Boehnhardt, H. T1 - The Rosetta Lander (“Philae”) Investigations / Bibring, J.-P. ; Rosenbauer, H. ; Boehnhardt, H. ; [...] Wittmann, K. JF - Space Science Reviews. 128 (2007), H. 1-4 Y1 - 2007 SN - 0038-6308 SP - 205 EP - 220 ER - TY - JOUR A1 - Weber, Hans-Joachim A1 - Mo, Xiumei A1 - Chen, Zonggang T1 - Electrospun nanofibers of collagen-chitosan and P(LLA-CL) for tissue engineering / Mo Xiumei, Chen Zonggang, Hans J. Weber JF - Frontiers of materials science in China. 1 (2007), H. 1 Y1 - 2007 SN - 1673-7377 SP - 20 EP - 23 PB - - ER - TY - JOUR A1 - Waller, Mark P. A1 - Braun, Heiko A1 - Hojdis, Nils A1 - Bühl, Michael T1 - Geometries of Second-Row Transition-Metal Complexes from Density-Functional Theory JF - Journal of Chemical Theory and Computation Y1 - 2007 U6 - http://dx.doi.org/10.1021/ct700178y SN - 1549-9626 VL - 3 IS - 6 SP - 2234 EP - 2242 ER - TY - JOUR A1 - Wagner, Torsten A1 - Schöning, Michael Josef T1 - Light-addressable potentiometric sensors (LAPS): recent trends and applications JF - Electrochemical sensor analysis / edited by S. Alegret ... Y1 - 2007 SN - 978-0-444-53053-0 N1 - Wilson & Wilson's comprehensive analytical chemistry ; 49 SP - 87 EP - 128 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Wagner, Torsten A1 - Molina, Roberto A1 - Yoshinobu, Tatsuo A1 - Kloock, Joachim P. A1 - Biselli, Manfred A1 - Canzoneri, Michele A1 - Schnitzler, Thomas A1 - Schöning, Michael Josef T1 - Handheld multi-channel LAPS device as a transducer platform for possible biological and chemical multi-sensor applications JF - Electrochimica Acta. 53 (2007), H. 2 Y1 - 2007 SN - 0013-4686 SP - 305 EP - 311 ER - TY - JOUR A1 - Wagner, Torsten A1 - Molina, R. A1 - Biselli, Manfred A1 - Canzoneri, Michele A1 - Schnitzler, Thomas A1 - Yoshinobu, Tatsuo A1 - Schöning, Michael Josef T1 - A light-addressable potentiometric sensor system for fast, simultaneous and spatial detection of the metabolic activity of biological cells JF - Transducers '07 Eurosensors XXI : digest of technical papers ; the14th International Conference on Solid-State Sensors, Actuators and Microsystems, June 10-14, 2007, Lyon, France / Gilles Delapierre (Ed.) Y1 - 2007 SN - 1-4244-0841-5 N1 - Eurosensors 21, 2007, Lyon ; International Conference on Solid-State Sensors, Actuators and Microsystems 14, 2007, Lyon SP - 1107 EP - 1110 PB - IEEE CY - Piscataway ER - TY - JOUR A1 - Wagner, Torsten A1 - Maris, Rob J. A1 - Ackermann, Hans-Josef A1 - Otto, Ralph A1 - Beging, Stefan A1 - Poghossian, Arshak A1 - Schöning, Michael Josef T1 - Handheld measurement device for field-effect sensor structures: Practical evaluation and limitations JF - Sensors and Actuators B: Chemical . 127 (2007), H. 1 Y1 - 2007 SN - 0925-4005 SP - 217 EP - 223 ER - TY - JOUR A1 - Wagner, Torsten A1 - Kloock, Joachim P. A1 - Schöning, Michael Josef T1 - Determination of cadmium concentration and pH value in aqueous solutions by means of a handheld light-addressable potentiometric sensor (LAPS) device JF - Electrochemical sensor analysis / edited by S. Alegret ... Y1 - 2007 SN - 978-0-444-53133-9 N1 - Wilson & Wilson's comprehensive analytical chemistry ; 49 SP - e35 EP - e44 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Vu, Duc Khoi A1 - Staat, Manfred A1 - Tran, Ich Thinh T1 - Analysis of pressure equipment by application of the primal-dual theory of shakedown JF - Communications in Numerical Methods in Engineering. 23 (2007), H. 3 Y1 - 2007 SN - 1069-8299 SP - 213 EP - 225 ER - TY - JOUR A1 - Vu, Duc Khoi A1 - Staat, Manfred T1 - Shakedown analysis of structures made of materials with temperature-dependent yield stress JF - International Journal of Solids and Structures. 44 (2007), H. 13 Y1 - 2007 SN - 0020-7683 SP - 4524 EP - 4540 ER - TY - JOUR A1 - Turek, Monika A1 - Ketterer, Lothar A1 - Claßen, Melanie A1 - Berndt, Heinz A1 - Elbers, Gereon A1 - Krüger, Peter A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Development and Electrochemical Investigations of an EIS-(Electrolyte-Insulator-Semiconductor) based Biosensor for Cyanide Detection JF - Sensors Y1 - 2007 SN - 1424-8220 VL - 7 IS - 8 SP - 1415 EP - 1426 ER - TY - JOUR A1 - Staat, Manfred A1 - Vu, Duc-Khoi T1 - Limit analysis of flaws in pressurized pipes and cylindrical vessels. Part I: Axial defects JF - Engineering Fracture Mechanics. 74 (2007), H. 3 Y1 - 2007 SN - 0013-7944 SP - 431 EP - 450 ER - TY - JOUR A1 - Sommer, Angela M. A1 - Bitz, Andreas A1 - Streckert, Joachim A1 - Hansen, Volkert W. A1 - Lerchl, Alexander T1 - Lymphoma development in mice chronically exposed to UMTS-modulated radiofrequency electromagnetic fields JF - Radiation Research Y1 - 2007 U6 - http://dx.doi.org/10.1667/RR0857.1 SN - 1938-5404 VL - 168 IS - 1 SP - 72 EP - 80 ER - TY - JOUR A1 - Seibler, Jost A1 - Kleinridders, Andre A1 - Küter-Luks, Birgit A1 - Niehaves, Sandra A1 - Brüning, Jens C. A1 - Schwenk, Frieder T1 - Reversible gene knockdown in mice using a tight, inducible shRNA expression system JF - Nucleic Acids Research Y1 - 2007 U6 - http://dx.doi.org/10.1093/nar/gkm122 SN - 1362-4962 VL - 35 IS - 7 SP - e54 ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Kloock, Joachim P. T1 - About 20 years of silicon-based thin-film sensors with chalcogenide glass materials for heavy metal analysis: Technological aspects of fabrication and miniaturization JF - Electroanalysis. 19 (2007), H. 19-20 Y1 - 2007 SN - 1040-0397 SP - 2029 EP - 2038 ER - TY - JOUR A1 - Schuh, G. A1 - Gottschalk, S. A1 - Höhne, Tim T1 - High Resolution Production Management JF - CIRP Annals Y1 - 2007 U6 - http://dx.doi.org/10.1016/j.cirp.2007.05.105 SN - 0007-8506 VL - 56 IS - 1 SP - 439 EP - 442 ER - TY - JOUR A1 - Schmitz, Philipp A1 - Weber, Martin T1 - Buying and selling behavior of individual investors in option-like securities Y1 - 2007 SP - 1 EP - 36 ER - TY - JOUR A1 - Robinson, A. E. A1 - Rönna, Uwe A1 - Funke, Harald T1 - Testing of a 10 kW diffusive micro-mix combustor for hydrogen-fuelled micro-scale gas turbines JF - International Workshop on Micro and Nanotechnology for Power Generation and Energy Conversion Applications <7, 2007, Freiburg, Breisgau> ; PowerMEMS ; 7 Y1 - 2007 SP - 225 EP - 228 ER - TY - JOUR A1 - Reinhardt, T. A1 - Bitz, Andreas A1 - El Ouardi, A. A1 - Streckert, J. A1 - Sommer, A. A1 - Lerchl, A. A1 - Hansen, V. T1 - Exposure set-ups for in vivo experiments using radial waveguides JF - Radiation Protection Dosimetry Y1 - 2007 U6 - http://dx.doi.org/10.1093/rpd/ncm370 SN - 1742-3406 VL - 124 IS - 1 SP - 21 EP - 26 ER - TY - JOUR A1 - Rath, V. A1 - Mottaghy, Darius T1 - Smooth inversion for ground surface temperature histories: estimating the optimum regularization parameter by generalized cross-validation JF - Geophysical Journal International Y1 - 2007 U6 - http://dx.doi.org/10.1111/j.1365-246X.2007.03587.x SN - 1365-246X VL - 171 IS - 3 SP - 1440 EP - 1448 ER - TY - JOUR A1 - Prume, Klaus A1 - Tyholdt, F. A1 - Calame, F. A1 - Raeder, H. T1 - Chemically derived seeding layer for {100}-textured PZT thin films / Tyholdt, F. ; Calame, F. ; Prume, K. ; Raeder, H. ; Muralt, P. JF - Journal of Electroceramics. 19 (2007), H. 4 Y1 - 2007 SN - 1385-3449 SP - 311 EP - 314 ER - TY - JOUR A1 - Prume, Klaus A1 - Raeder, H. A1 - Tyholdt, F. A1 - Booij, W. E. T1 - Taking piezoelectric microsystems from the laboratory to production / Raeder, H. ; Tyholdt, F. ; Booij, W. ; Calame, F. ; Ostbo, N. P. ; Bredesen, R. ; Prume, K. ; Rijnders, G. ; Muralt, P. JF - Journal of Electroceramics. 19 (2007), H. 4 Y1 - 2007 SN - 1385-3449 SP - 357 EP - 362 ER - TY - JOUR A1 - Prume, Klaus A1 - Muralt, Paul A1 - Calame, Florian A1 - Schmitz-Kempen, Thorsten T1 - Extensive electromechanical characterization of PZT thin films for MEMS applications by electrical and mechanical excitation signals / Prume, Klaus ; Muralt, Paul ; Calame, Florian ; Schmitz-Kempen, Thorsten ; Tiedke, Stephan JF - Journal of Electroceramics. 19 (2007), H. 4 Y1 - 2007 SN - 1385-3449 SP - 407 EP - 411 ER - TY - JOUR A1 - Prume, Klaus A1 - Muralt, P. A1 - Calame, F. A1 - Schmitz-Kempen, T. T1 - Piezoelectric thin films: evaluation of electrical and electromechanical characteristics for MEMS devices / Prume, K. ; Muralt, P. ; Calame, F. ; Schmitz-Kempen, T. ; Tiedke, S. ; JF - IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control. 54 (2007), H. 1 Y1 - 2007 SN - 0885-3010 SP - 81 EP - 14 ER - TY - JOUR A1 - Prume, Klaus A1 - Booij, W. E. A1 - Vogl, A. H. A1 - Wang, D. T. T1 - A simple and powerful analytical model for MEMS piezoelectric multimorphs / Booij, W. E. ; Vogl, A. H. ; Wang, D. T. ; Tyholdt, F. ; Ostbo, N. P. ; Raeder, H. ; Prume, K. JF - Journal of Electroceramics. 19 (2007), H. 4 Y1 - 2007 SN - 1385-3449 SP - 387 EP - 393 ER - TY - JOUR A1 - Prume, Klaus T1 - Electrical and electromechanical characterization of piezoelectric thin films in view of MEMS application / Tiedke, S. ; Prume, K. ; Schmitz-Kempen, T.; Y1 - 2007 N1 - ISAF 2007. Sixteenth IEEE International Symposium on Applications of Ferroelectrics, 2007 SP - 702 ER - TY - JOUR A1 - Poghossian, Arshak A1 - Schöning, Michael Josef T1 - Chemical and biological field-effect sensors for liquids – a status report JF - Handbook of biosensors and biochips / ed. Robert S. Marks ... Bd. 1 Y1 - 2007 SN - 978-0-470-01905-4 SP - 395 EP - 412 PB - Wiley CY - Chichester ER - TY - JOUR A1 - Poghossian, Arshak A1 - Ingebrandt, S. A1 - Abouzar, Maryam H. A1 - Schöning, Michael Josef T1 - Label-free detection of charged macromolecules by using a field-effect-based sensor platform: Experiments and possible mechanisms of signal generation JF - Applied Physics A: Materials Science & Processing. 87 (2007), H. 3 Y1 - 2007 SN - 0947-8396 N1 - Special Issue “From Surface Science to Nanoscale Devices” SP - 517 EP - 524 ER - TY - JOUR A1 - Poghossian, Arshak A1 - Abouzar, Maryam H. A1 - Christiaens, P. A1 - Williams, O. A. A1 - Haenen, K. A1 - Wagner, P. A1 - Schöning, Michael Josef T1 - Nanocrystalline diamond-based field-effect (bio-)chemical sensor JF - 8. Dresdner Sensor-Symposium : Sensoren für Umwelt, Klima und Sicherheit, Biosensoren und Biosysteme, Sensoren und Sensorsysteme für die Prozesstechnik, Trends in der Sensortechnik, Materialentwicklung für die Sensorik; 8. Dresdner Sensor-Symposium, 10. - 12. Dezember 2007, Dresden / Gerald Gerlach ... (Hg.) Y1 - 2007 SN - 978-3-940046-45-1 N1 - Dresdner Sensor-Symposium <8, 2007, Dresden> ; Dresdner Beiträge zur Sensorik ; 29 SP - 191 EP - 194 PB - TUDpress, Verl. der Wissenschaften CY - Dresden ER - TY - JOUR A1 - Poghossian, Arshak A1 - Abouzar, Maryam H. A1 - Amberger, F. A1 - Mayer, D. A1 - Han, Y. A1 - Ingebrandt, S. A1 - Offenhäusser, A. A1 - Schöning, Michael Josef T1 - Field-effect sensors with charged macromolecules: Characterisation by capacitance–voltage, constant-capacitance, impedance spectroscopy and atomic-force microscopy methods JF - Biosensors and Bioelectronics. 22 (2007), H. 9-10 Y1 - 2007 SN - 0956-5663 N1 - Selected Papers from the Ninth World Congress On Biosensors. Toronto, Canada 10 - 12 May 2006, Alice X. J . Tang SP - 2100 EP - 2107 ER - TY - JOUR A1 - Pietsch, Wolfram T1 - IT Service Deployment JF - QFD : transactions from International Symposium on QFD 2007 - Williamsburg, the Nineteenth Symposium on Quality Function Deployment ; September 7 - 8, 2007, Williamsburg, VA ; [companion document to the Thirteenth International and Nineteenth North American Symposium on Quality Function Deployment (ISQFD'07)] / [organized and hosted by the QFD Institute] Y1 - 2007 SN - 1-889477-19-2 N1 - QFD 2007, 19th Symposium on Quality Function Deployment, Williamsburg, VA, US, Sep 7-8, 2007 SP - 203 EP - 212 PB - QFD Inst. CY - Ann Arbor, Mich. ER - TY - JOUR A1 - Paulßen, Elisabeth A1 - Kückmann, Theresa A1 - Abram, Ulrich T1 - Silver(I) Complexes of 1,3-Dialkyl-4,5-dimethylimidazol-2-ylidenes and their Use as Precursors for the Synthesis of Rhenium(V) NHC Complexes JF - Zeitschrift für anorganische und allgemeine Chemie : ZAAC = Journal of inorganic and general chemistry Y1 - 2007 U6 - http://dx.doi.org/10.1002/zaac.200700021 SN - 1521-3749 VL - 633 IS - 5-6 SP - 830 EP - 834 ER - TY - JOUR A1 - Overduin, James A1 - Blome, Hans-Joachim A1 - Hoell, Josef T1 - Wolfgang Priester: from the big bounce to the Lambda-dominated universe JF - Naturwissenschaften Y1 - 2007 SN - 0028-1042 VL - 94 IS - 6 SP - 417 EP - 429 ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Protic, D. A1 - Krings, T. A1 - Niessen, S. T1 - Position-Sensitive Si(Li) Transmission Detectors for the EXL-Experiments at GSI-Darmstadt. JF - Scientific Report / GSi Gesellschaft für Schwerionenforschung, Darmstadt. 2007 (2007), H. 1 Y1 - 2007 SN - 0174-0814 N1 - Fair-Experiments-31; GSI Report 2007-1, June 2007 ; GSI Scientific Report 2006 SP - 33 ER - TY - JOUR A1 - Mistler, Michael A1 - Anthoine, A. A1 - Butenweg, Christoph T1 - In-plane and out-of-plane homogenisation of masonry JF - Computers & structures Y1 - 2007 U6 - http://dx.doi.org/10.1016/j.compstruc.2006.08.087 SN - 1879-2243 (E-Journal); 0045-7949 (Print) VL - Volume 85 IS - Issues 17-18 SP - 1321 EP - 1330 ER - TY - JOUR A1 - McArdell, Brian W. A1 - Bartelt, Perry A1 - Kowalski, Julia T1 - Field observations of basal forces and fluid pore pressure in a debris flow JF - Geophysical Research Letters (GRL) N2 - Using results from an 8 m2 instrumented force plate we describe field measurements of normal and shear stresses, and fluid pore pressure for a debris flow. The flow depth increased from 0.1 to 1 m within the first 12 s of flow front arrival, remained relatively constant until 100 s, and then gradually decreased to 0.5 m by 600 s. Normal and shear stresses and pore fluid pressure varied in-phase with the flow depth. Calculated bulk densities are ρb = 2000–2250 kg m−3 for the bulk flow and ρf = 1600–1750 kg m−3 for the fluid phase. The ratio of effective normal stress to shear stress yields a Coulomb basal friction angle of ϕ = 26° at the flow front. We did not find a strong correlation between the degree of agitation in the flow, estimated using the signal from a geophone on the force plate, and an assumed dynamic pore fluid pressure. Our data support the idea that excess pore-fluid pressures are long lived in debris flows and therefore contribute to their unusual mobility. KW - debris flow Y1 - 2007 SN - 0094-8276 VL - 34 IS - 7 ER - TY - JOUR A1 - Mang, Thomas A1 - Roosen, Christoph A1 - Ansorge-Schumacher, Marion A1 - Leitner, Walter T1 - Gaining pH-control in water/carbon dioxide biphasic systems / Roosen, Christoph ; Ansorge-Schumacher, Marion ; Mang, Thomas ; Leitner, Walter ; Greiner, Lasse JF - Green Chemistry. 9 (2007) Y1 - 2007 SN - 1463-9262 SP - 455 EP - 458 ER - TY - JOUR A1 - Mang, Thomas A1 - Kolz, J. A1 - Martins, J. A1 - Kremer, K. T1 - Investigation of the Elastomer-Foam Production with Single-Sided NMR / Kolz, J. ; Martins, J. ; Kremer, K. ; Mang, Thomas ; Blümich, B. JF - Kautschuk Gummi Kunststoffe. 60 (2007), H. 4 Y1 - 2007 SN - 0948-3276 SP - 179 EP - 183 ER - TY - JOUR A1 - Mang, Thomas A1 - Kolz, J. A1 - Hunger, K. A1 - Rath, S. T1 - Investigation of self-diffusion processes in ionic hydrogels with a single-sided sensor / Kolz, J. ; Hunger, K. ; Rath, S. ; Mang, T. ; Blümich, B. JF - Magnetic Resonance Imaging. 25 (2007), H. 4 Y1 - 2007 SN - 0730-725X N1 - Proceedings of the Eighth International Bologna Conference on Magnetic Resonance in Porous Media SP - 566 EP - 567 ER - TY - JOUR A1 - Mang, Thomas A1 - Kolz, J. A1 - Goga, N. A1 - Casanova, F. T1 - Spatial localization with single-sided NMR sensors / Kolz, J. ; Goga, N. ; Casanova, F. ; Mang, T. ; Blümich, B. JF - Applied Magnetic Resonance. 32 (2007), H. 1-2 Y1 - 2007 SN - 0937-9347 SP - 171 EP - 184 ER - TY - JOUR A1 - Linder, Peter A1 - Digel, Ilya A1 - Temiz Artmann, Aysegül A1 - Kayser, Peter A1 - Porst, Dariusz A1 - Artmann, Gerhard T1 - High-throughput testing of mechanical forces generated in thin cell and tissue layers JF - Tissue Engineering. 13 (2007), H. 7 Y1 - 2007 SN - 1076-3279 N1 - Meeting abstract 433 SP - 1778 EP - 1778 ER - TY - JOUR A1 - Ley, Wilfried A1 - Plescher, Engelbert A1 - Scholz, Artur A1 - Piepenbrock, Johannes T1 - COMPASS-1 picosatellite project / Ley, Wilfried ; Plescher, Engelbert ; Scholz, Artur ; Piepenbrock, Johannes JF - Small satellites for earth observation : digest of the 6th International symposium of the International Academy of Astronautics, Berlin, April 23 - 26, 2007 / ed. by Rainer Sandau; Hans-Peter Röser; Arnoldo Valenzuela Y1 - 2007 SN - 9783896855718 N1 - Symposium on Small Satellites for Earth Observation ; (6, 2007, Berlin) SP - 147 EP - 150 PB - Wissenschaft und Technik Verl. CY - Berlin ER - TY - JOUR A1 - Lehnertz, Klaus A1 - Mormann, Florian A1 - Osterhage, Hannes A1 - Andy, Müller A1 - Prusseit, Jens A1 - Chernihovskyi, Anton A1 - Staniek, Matthäus A1 - Krug, Dieter A1 - Bialonski, Stephan A1 - Elger, Christian E. T1 - State-of-the-art of seizure prediction JF - Journal of Clinical Neurophysiology Y1 - 2007 U6 - http://dx.doi.org/10.1097/WNP.0b013e3180336f16 SN - 1537-1603 VL - 24 IS - 2 SP - 147 EP - 153 ER - TY - JOUR A1 - Kroll-Ludwigs, Kathrin T1 - The Reform of German Maintenance Law JF - The International Survey of Family Law Y1 - 2018 SP - 85 EP - 100 ER - TY - JOUR A1 - Krause, Gregor A1 - Rodriguez, Jackson A1 - Stopic, Srecko A1 - Friedrich, Bernd T1 - Feasibility assessment of electrocoagulation towards a new sustainable wastewater treatment / Rodriguez, Jackson ; Stopic, Srecko ; Krause Gregor ; Friedrich, Bernd JF - Environmental Science and Pollution Research. 14 (2007), H. 7 Y1 - 2007 SN - 0944-1344 SP - 477 EP - 482 ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Maier, Mathias A1 - Bauer, Svetlana A1 - Feucht, Nikolaus T1 - Effect of intravitreal injections and volume changes on intraocular pressure: clinical results and biomechanical model / Kotliar, Konstantin ; Maier, Mathias ; Bauer, Svetlana ; Feucht, Nikolaus ; Lohmann, Chris ; Lanzl, Ines JF - Acta Ophthalmologica Scandinavica. 85 (2007), H. 7 Y1 - 2007 SN - 1755-3768 SP - 777 EP - 781 PB - - ER - TY - JOUR A1 - Kappler-Tanudyaya, Nathalie A1 - Schmitt, Heike A1 - Tippkötter, Nils A1 - Meyer, Lina A1 - Lenzen, Sigurd A1 - Ulber, Roland T1 - Combination of biotransformation and chromatography for the isolation and purification of mannoheptulose JF - Biotechnology Journal N2 - Mannoheptulose is a seven-carbon sugar. It is an inhibitor of glucose-induced insulin secretion due to its ability to selectively inhibit the enzyme glucokinase. An improved procedure for mannoheptulose isolation from avocados is described in this study (based upon the original method by La Forge). The study focuses on the combination of biotransformation and downstream processing (preparative chromatography) as an efficient method to produce a pure extract of mannoheptulose. The experiments were divided into two major phases. In the first phase, several methods and parameters were compared to optimize the mannoheptulose extraction with respect to efficiency and purity. In the second phase, a mass balance of mannoheptulose over the whole extraction process was undertaken to estimate the yield and efficiency of the total extraction process. The combination of biotransformation and preparative chromatography allowed the production of a pure mannoheptulose extract. In a biological test, the sugar inhibited the glucokinase enzyme activity efficiently. Y1 - 2007 U6 - http://dx.doi.org/10.1002/biot.200700004 SN - 1860-7314 VL - 2 IS - 6 SP - 692 EP - 699 ER - TY - JOUR A1 - Kaminsky, Radoslav A1 - Kallweit, Stephan A1 - Weber, Hans-Joachim A1 - Claessens, Tom A1 - Jozwik, Krzystof A1 - Verdonck, Pascal T1 - Flow visualization through two types of aortic prosthetic heart valves using stereoscopic high-speed particle image velocimetry JF - Artificial organs. 31 (2007), H. 12 Y1 - 2007 SN - 1525-1594 SP - 869 EP - 879 ER -