TY - JOUR A1 - Artmann, Gerhard A1 - Hueck, Isgard S. A1 - Rossiter, Katharine A1 - Schmid-Schönbein, Geert W. T1 - Fluid Shear Attenuates Endothelial Pseudopodia Formation into the Capillary Lumen / Hueck, Isgard S. ; Rossiter, Katharine ; Artman, Gerhard M. ; Schmid-Schönbein, Geert W. JF - Microcirculation. 15 (2008), H. 6 Y1 - 2008 SN - 1549-8719 SP - 531 EP - 542 ER - TY - JOUR A1 - Artmann, Gerhard A1 - Hueck, I. S. A1 - Hollweg, H. G. A1 - Schmid-Schönbein, G. W. T1 - Chlorpromazine modulates the Morphological Macro- and Microstructure of Endothelial Cells. Hueck, I. S.; Hollweg, H. G.; Schmid-Schönbein, G. W.; Artmann, Gerhard Michael JF - American Journal of Physiology. Cell Physiology. 278 (2000), H. 5 Y1 - 2000 SN - 1522-1563 N1 - Zählung: C873- C878 SP - 873 EP - 878 ER - TY - JOUR A1 - Artmann, Gerhard A1 - Hovav, T. A1 - Goldfarb, A. A1 - Yedgar, S. [u.a.] T1 - Enhanced adherence of beta-thalassaemic erythrocytes to endothelial cells. Hovav, T., Goldfarb, A.; Artmann, Gerhard Michael, Yedgar, S.; Barstein, G. JF - British Journal of Haematology. 106 (1999), H. 1 Y1 - 1999 SN - 1365-2141 SP - 178 EP - 181 ER - TY - JOUR A1 - Artmann, Gerhard A1 - Grebe, R. A1 - Homrighausen, A. A1 - Wolff, H. A1 - [u.a.], T1 - Response of normal and diabetic erythrocytes to membrane deformation by chemical and mechanical forces. Artmann, Gerhard Michael; Grebe, R.; Homrighausen, A.; Wolff, H.; Teitel, P.; Schmid-Schönbein, H. JF - 12. Jahrestagung der Gesellschaft für Mikrozirkulation Y1 - 1988 SP - 196 EP - 200 PB - Karger [u.a.] CY - Basel [u.a.] ER - TY - JOUR A1 - Artmann, Gerhard A1 - Gorbatenkova, E. A. A1 - Panasenko, O. M. T1 - Hypochlorous acid and human blood low density lipoproteins modified by hypochlorous acid increase erythrocyte adhesion to endothelial cells. Gorbatenkova, E. A.; Artmann, Gerhard Michael; Panasenko, O. M. JF - Membrane and cell biology. 13 (2000), H. 4 Y1 - 2000 SN - 1023-6597 SP - 537 EP - 546 ER - TY - JOUR A1 - Artmann, Gerhard A1 - Digel, Ilya A1 - Zerlin, Kay A1 - Maggakis-Kelemen, Christina A1 - Linder, Peter A1 - Porst, Dariusz A1 - Kayser, Peter A1 - Stadler, David A1 - Dikta, Gerhard A1 - Temiz Artmann, Aysegül T1 - Hemoglobin senses body temperature JF - European Biophysics Journal Y1 - 2009 SN - 0175-7571 VL - 38 IS - 5 SP - 589 EP - 600 ER - TY - JOUR A1 - Artmann, Gerhard A1 - Digel, Ilya A1 - Linder, Peter A1 - Porst, Dariusz T1 - Mechanism of haemoglobin sensing body temperature JF - Tissue Engineering Part A. 14 (2008), H. 5 Y1 - 2008 SN - 1937-3341 N1 - TERMIS EU 2008 Porto Meeting June 22–26, 2008 Porto Congress Center–Alfândega Portugal SP - 754 EP - 754 ER - TY - JOUR A1 - Artmann, Gerhard A1 - Bäumler, H. A1 - Voigt, A. A1 - Mitlöhner, R. [u.a.] T1 - Plastic behaviour of polyelectrolyte microcapsules derived from colloid templates. Bäumler, H., Artmann, Gerhard Michael; Voigt, A., Mitlöhner, R., Neu, B., Kiesewetter, H. JF - Journal of Microencapsulation. 17 (2000), H. 5 Y1 - 2000 SN - 1464-5246 SP - 651 EP - 655 ER - TY - JOUR A1 - Artmann, Gerhard A1 - Burns, Laura A1 - Canaves, Jaume M. A1 - Temiz Artmann, Aysegül T1 - Circular dichroism spectra of human hemoglobin reveal a reversible structural transition at body temperature JF - European Biophysics Journal. 33 (2004), H. 6 Y1 - 2004 SN - 1432-1017 SP - 490 EP - 496 ER - TY - JOUR A1 - Artmann, Gerhard T1 - A microscopic photometric method for measuring erythrocyte deformability. Artmann, Gerhard Michael JF - Clinical Hemorheology. 6 (1986) Y1 - 1986 SN - 0271-5198 SP - 617 EP - 627 ER - TY - JOUR A1 - Artmann, Gerhard T1 - 2nd International Conference on Medical Biorheology (ICMB). Shanghai, China, September 13-15, 1995. Shi, Young de, Artmann, Gerhard Michael, Meiselman, Herbert J. JF - Biorheology. 33 (1996), H. 6 Y1 - 1996 SN - 0006-355x SP - 505 EP - 507 ER - TY - JOUR A1 - Artmann, Gerhard T1 - Microscopic photometric quantification of stiffness and relaxation time of red blood cells in a flow chamber. Artmann, Gerhard Michael JF - Biorheology. 32 (1995), H. 5 Y1 - 1995 SN - 0006-355x SP - 553 EP - 570 ER - TY - JOUR A1 - Artmann, Gerhard T1 - Cellular engineering - a challenge for engineers? / Artmann, G. M. JF - Biomedizinische Technik = Biomedical Engineering. 45 (2000), H. s1 Y1 - 2000 SN - 1862-278X SP - 449 ER - TY - JOUR A1 - Arreola, Julio A1 - Oberländer, Jan A1 - Mätzkow, M. A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Surface functionalization for spore-based biosensors with organosilanes JF - Electrochimica Acta N2 - In the present work, surface functionalization of different sensor materials was studied. Organosilanes are well known to serve as coupling agent for biomolecules or cells on inorganic materials. 3-aminopropyltriethoxysilane (APTES) was used to attach microbiological spores time to an interdigitated sensor surface. The functionality and physical properties of APTES were studied on isolated sensor materials, namely silicon dioxide (SiO2) and platinum (Pt) as well as the combined material on sensor level. A predominant immobilization of spores could be demonstrated on SiO2 surfaces. Additionally, the impedance signal of APTES-functionalized biosensor chips has been investigated. Y1 - 2017 U6 - https://doi.org/10.1016/j.electacta.2017.04.157 SN - 0013-4686 VL - 241 SP - 237 EP - 243 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Arreola, Julio A1 - Mätzkow, Malte A1 - Durán, Marlena Palomar A1 - Greeff, Anton A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Optimization of the immobilization of bacterial spores on glass substrates with organosilanes JF - Physica status solidi (A) : Applications and materials science N2 - Spores can be immobilized on biosensors to function as sensitive recognition elements. However, the immobilization can affect the sensitivity and reproducibility of the sensor signal. In this work, three different immobilization strategies with organosilanes were optimized and characterized to immobilize Bacillus atrophaeus spores on glass substrates. Five different silanization parameters were investigated: nature of the solvent, concentration of the silane, silanization time, curing process, and silanization temperature. The resulting silane layers were resistant to a buffer solution (e.g., Ringer solution) with a polysorbate (e.g., Tween®80) and sonication. KW - silanization KW - organosilanes KW - immobilization KW - endospores KW - biosensors KW - Bacillus atrophaeus Y1 - 2016 U6 - https://doi.org/10.1002/pssa.201532914 SN - 1862-6319 VL - 213 IS - 6 SP - 1463 EP - 1470 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Arreola, Julio A1 - Keusgen, Michael A1 - Wagner, Torsten A1 - Schöning, Michael Josef T1 - Combined calorimetric gas- and spore-based biosensor array for online monitoring and sterility assurance of gaseous hydrogen peroxide in aseptic filling machines JF - Biosensors and Bioelectronics Y1 - 2019 U6 - https://doi.org/10.1016/j.bios.2019.111628 SN - 0956-5663 VL - 143 IS - 111628 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Arreola, Julio A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Toward an immobilization method for spore-based biosensors in oxidative environment JF - Electrochimica Acta Y1 - 2019 U6 - https://doi.org/10.1016/j.electacta.2019.01.148 VL - 302 SP - 394 EP - 401 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Arreola, Julio A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Effect of O2 plasma on properties of electrolyte-insulator-semiconductor structures JF - physica status solidi a : applications and materials sciences N2 - Prior to immobilization of biomolecules or cells onto biosensor surfaces, the surface must be physically or chemically activated for further functionalization. Organosilanes are a versatile option as they facilitate the immobilization through their terminal groups and also display self-assembly. Incorporating hydroxyl groups is one of the important methods for primary immobilization. This can be done, for example, with oxygen plasma treatment. However, this treatment can affect the performance of the biosensors and this effect is not quite well understood for surface functionalization. In this work, the effect of O2 plasma treatment on EIS sensors was investigated by means of electrochemical characterizations: capacitance–voltage (C–V) and constant capacitance (ConCap) measurements. After O2 plasma treatment, the potential of the EIS sensor dramatically shifts to a more negative value. This was successfully reset by using an annealing process. KW - surface functionalization KW - O2 plasma KW - hydroxylation KW - electrolyte-insulator semiconductor sensor (EIS) KW - annealing Y1 - 2017 U6 - https://doi.org/10.1002/pssa.201700025 SN - 1862-6319 VL - 214 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Arpshofen, Ingo A1 - Pool, M. J. A1 - Sommer, Ferdinand A1 - Gerling, Ulrich A1 - Predel, Bruno A1 - Schultheiss, Emil T1 - Determination of the integral mixing enthalpies in the Cu-Pd-Si liquid ternary alloy system at 1600 K JF - Zeitschrift für Metallkunde : international journal of materials research and advanced techniques. Bd. 74, H. 1 Y1 - 1983 SN - 0044-3093 ; 0179-4841 SP - 25 EP - 32 ER - TY - JOUR A1 - Arpshofen, Ingo A1 - Gerling, Ulrich A1 - Sommer, Ferdinand A1 - Schultheiss, Emil A1 - Predel, Bruno A1 - Pool, M. J. T1 - Experimentelle Bestimmung der integralen Mischungsenthalpien in den binären Systemen Pd-Cu und Si-Cu bei 1600 K JF - Zeitschrift für Metallkunde : international journal of materials research and advanced techniques. Bd. 72, H. 12 Y1 - 1981 SN - 0044-3093 ; 0179-4841 SP - 842 EP - 846 ER - TY - JOUR A1 - Arpshofen, Ingo A1 - Gerling, Ulrich A1 - Sommer, Ferdinand A1 - Schultheiss, Emil A1 - Predel, Bruno A1 - Pool, M. J. T1 - Bestimmung der Mischungsenthalpien im System Palladium-Silicium bei 1600 K JF - Zeitschrift für Metallkunde : international journal of materials research and advanced techniques. Bd. 72, H. 11 Y1 - 1981 SN - 0044-3093 ; 0179-4841 SP - 776 EP - 781 ER - TY - JOUR A1 - Arinkin, Vladimir A1 - Digel, Ilya A1 - Porst, Dariusz A1 - Temiz Artmann, Aysegül A1 - Artmann, Gerhard T1 - Phenotyping date palm varieties via leaflet cross-sectional imaging and artificial neural network application JF - BMC bioinformatics N2 - Background True date palms (Phoenix dactylifera L.) are impressive trees and have served as an indispensable source of food for mankind in tropical and subtropical countries for centuries. The aim of this study is to differentiate date palm tree varieties by analysing leaflet cross sections with technical/optical methods and artificial neural networks (ANN). Results Fluorescence microscopy images of leaflet cross sections have been taken from a set of five date palm tree cultivars (Hewlat al Jouf, Khlas, Nabot Soltan, Shishi, Um Raheem). After features extraction from images, the obtained data have been fed in a multilayer perceptron ANN with backpropagation learning algorithm. Conclusions Overall, an accurate result in prediction and differentiation of date palm tree cultivars was achieved with average prediction in tenfold cross-validation is 89.1% and reached 100% in one of the best ANN. Y1 - 2014 U6 - https://doi.org/10.1186/1471-2105-15-55 SN - 1471-2105 VL - 15 IS - 55 SP - 1 EP - 8 ER - TY - JOUR A1 - Arida, Hassan A1 - Turek, Monika A1 - Rolka, David A1 - Schöning, Michael Josef T1 - A Novel Thin-Film Copper Array Based on an Organic/Inorganic Sensor Hybrid: Microfabrication, Potentiometric Characterization, and Flow-Injection Analysis Application JF - Electroanalysis. 21 (2009), H. 10 Y1 - 2009 SN - 1040-0397 SP - 1145 EP - 1151 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Arida, Hassan A1 - Mohsen, Q. A1 - Schöning, Michael Josef T1 - Microfabrication, characterization and analytical application of a new thin-film silver microsensor JF - Electrochimica Acta. 54 (2009), H. 13 Y1 - 2009 SN - 0013-4686 SP - 3543 EP - 3547 ER - TY - JOUR A1 - Arida, Hassan A. A1 - Al-haddad, Ameera A1 - Schöning, Michael Josef T1 - New Solid-State Organic Membrane Based Lead-Selective Micro-Electrode JF - International Journal of Electrochemical Science. 6 (2011), H. 9 Y1 - 2011 SN - 1452-3981 SP - 3858 EP - 3867 ER - TY - JOUR A1 - Arampatzis, Adamantios A1 - Peper, Andreas A1 - Bierbaum, Stefanie A1 - Albracht, Kirsten T1 - Plasticity of human Achilles tendon mechanical and morphological properties in response to cyclic strain JF - Journal of Biomechanics N2 - The purpose of the current study in combination with our previous published data (Arampatzis et al., 2007) was to examine the effects of a controlled modulation of strain magnitude and strain frequency applied to the Achilles tendon on the plasticity of tendon mechanical and morphological properties. Eleven male adults (23.9±2.2 yr) participated in the study. The participants exercised one leg at low magnitude tendon strain (2.97±0.47%), and the other leg at high tendon strain magnitude (4.72±1.08%) of similar frequency (0.5 Hz, 1 s loading, 1 s relaxation) and exercise volume (integral of the plantar flexion moment over time) for 14 weeks, 4 days per week, 5 sets per session. The exercise volume was similar to the intervention of our earlier study (0.17 Hz frequency; 3 s loading, 3 s relaxation) allowing a direct comparison of the results. Before and after the intervention ankle joint moment has been measured by a dynamometer, tendon–aponeurosis elongation by ultrasound and cross-sectional area of the Achilles tendon by magnet resonance images (MRI). We found a decrease in strain at a given tendon force, an increase in tendon–aponeurosis stiffness and tendon elastic modulus of the Achilles tendon only in the leg exercised at high strain magnitude. The cross-sectional area (CSA) of the Achilles tendon did not show any statistically significant (P>0.05) differences to the pre-exercise values in both legs. The results indicate a superior improvement in tendon properties (stiffness, elastic modulus and CSA) at the low frequency (0.17 Hz) compared to the high strain frequency (0.5 Hz) protocol. These findings provide evidence that the strain magnitude applied to the Achilles tendon should exceed the value, which occurs during habitual activities to trigger adaptational effects and that higher tendon strain duration per contraction leads to superior tendon adaptational responses. Y1 - 2010 U6 - https://doi.org/10.1016/j.jbiomech.2010.08.014 SN - 0021-9290 VL - 43 IS - 16 SP - 3073 EP - 3079 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Arampatzis, Adamantios A1 - Karamanidis, Kiros A1 - Mademli, Lida A1 - Albracht, Kirsten T1 - Plasticity of the human tendon to short and long-term mechanical loading JF - Exercise and Sport Sciences Reviews Y1 - 2009 U6 - https://doi.org/10.1097/JES.0b013e31819c2e1d SN - 1538-3008 VL - 37 IS - 2 SP - 66 EP - 72 ER - TY - JOUR A1 - Arampatzis, Adamantios A1 - Karamanidis, Kiros A1 - Albracht, Kirsten T1 - Adaptational responses of the human Achilles tendon by modulation of the applied cyclic strain magnitude JF - Journal of Experimental Biology Y1 - 2007 U6 - https://doi.org/10.1242/jeb.003814 SN - 0022-0949 VL - 210 IS - 15 SP - 2743 EP - 2753 ER - TY - JOUR A1 - Anik, Sabri A1 - Tuelbentci, K. T1 - Lichtbogenschweißen : Untersuchung der Schweißschlacke und der Wirkungen auf das Entfernen der Schlacke beim Lichtbogenschweißen ; Teil 1 JF - Technische Rundschau : TR ; das Schweizer Industrie-Magazin Y1 - 1973 SN - 0040-148X VL - 65 IS - 48 SP - 13 EP - 15 PB - Medtrix Group CY - Basel ER - TY - JOUR A1 - Anik, Sabri A1 - Tuelbentci, K. T1 - Lichtbogenschweißen : Untersuchung der Schweißschlacke und der Wirkungen auf das Entfernen der Schlacke ; Teil 2 JF - Technische Rundschau : TR ; das Schweizer Industrie-Magazin Y1 - 1973 SN - 0040-148X VL - 65 IS - 52 SP - 9 EP - 13 PB - Medtrix Group CY - Basel ER - TY - JOUR A1 - Anik, Sabri A1 - Tuelbentci, K. T1 - Lichtbogenschweißen : Untersuchung der Schweißschlacke und der Wirkungen auf das Entfernen der Schlacke ; Teil 3 JF - Technische Rundschau : TR ; das Schweizer Industrie-Magazin Y1 - 1974 SN - 0040-148X VL - 66 IS - 2 SP - 43 EP - 47 PB - Medtrix Group CY - Basel ER - TY - JOUR A1 - Anik, Sabri A1 - Topuz, A. A1 - Tuncel, H. S. T1 - Einfluß der Parameter beim Diffusionsschweißen der Stähle X210Cr12 mit 25 CrMo4 auf die Ausbildung der Bindezone JF - Schweißen und Schneiden : Fachzeitschrift für Schweißen und verwandte Verfahren Y1 - 1992 SN - 0036 VL - 44 IS - 2 SP - 97 EP - 100 ER - TY - JOUR A1 - Anik, Sabri A1 - Topuz, A. A1 - Tuncel, H. S. T1 - Einfluß der Parameter beim Diffusionsschweißen der Stähle X 210 Cr 12 und 25 MoCr 4 auf ihre mechanischen Eigenschaften JF - Schweißen und Schneiden : Fachzeitschrift für Schweißen und verwandte Verfahren Y1 - 1991 SN - 0036-7184 VL - 43 IS - 6 SP - 341 EP - 344 ER - TY - JOUR A1 - Anik, Sabri A1 - Kapoor, Madan Lal A1 - Frohberg, Martin G. T1 - Thermodynamic behaviour of oxygen in molten substitutional alloy solvents JF - Zeitschrift für Metallkunde Y1 - 1983 SN - 0044-3093 VL - 74 IS - 1 SP - 53 EP - 58 ER - TY - JOUR A1 - Anik, Sabri A1 - Frohberg, Martin G. A1 - Kapoor, Madan Lal T1 - Untersuchungen zum thermodynamischen Verhalten des Sauerstoffs in Kupfer-Wismut-Schmelzen bei 1200°C JF - Zeitschrift für Physikalische Chemie Y1 - 1982 SN - 0942-9352 VL - 133 IS - 2 SP - 167 EP - 174 ER - TY - JOUR A1 - Anik, Sabri A1 - Frohberg, Martin G. A1 - Kapoor, Madan Lal T1 - Experiments and theoretical considerations on the solution of oxygen in binary metal alloys JF - Berichte der Bunsengesellschaft für physikalische Chemie Y1 - 1983 SN - 0005-9021 SN - 0940-483X VL - 87 IS - 12 SP - 1201 EP - 1204 ER - TY - JOUR A1 - Anik, Sabri A1 - Frohberg, Martin G. A1 - Kapoor, Madan Lal T1 - Prediction of thermodynamic properties of oxygen in binary metallic solvents JF - Zeitschrift für Metallkunde Y1 - 1983 SN - 0044-3093 VL - 74 IS - 6 SP - 372 EP - 375 ER - TY - JOUR A1 - Anik, Sabri A1 - Frohberg, Martin G. T1 - Thermodynamics and solubility of oxygen in liquid copper-lead alloys at 1200°C from E.M.F. measurements JF - Berichte der Bunsengesellschaft für physikalische Chemie Y1 - 1984 SN - 0940-483X SN - 0005-9021 VL - 88 IS - 8 SP - 707 EP - 710 ER - TY - JOUR A1 - Anik, Sabri A1 - Frohberg, Martin G. T1 - Thermodynamics and solubility of oxygen in liquid bismuth-lead and bismuth-antimony alloys JF - Berichte der Bunsengesellschaft für physikalische Chemie Y1 - 1987 SN - 0940-483X SN - 0005-9021 VL - 91 IS - 7 SP - 790 EP - 794 ER - TY - JOUR A1 - Anik, Sabri A1 - Frohberg, Martin G. T1 - Investigations of the thermodynamics of oxygen and the determination of the miscibility gap in the system copper-oxygen-lead at 12000C JF - Zeitschrift für Metallkunde Y1 - 1984 SN - 0044-3093 VL - 75 IS - 8 SP - 586 EP - 589 ER - TY - JOUR A1 - Anik, Sabri A1 - Frohberg, Martin G. T1 - Investigation of the thermodynamics of oxygen and the determination of phase boundaries in the system copper-oxygen-bismuth at 12000C JF - Zeitschrift für Metallkunde Y1 - 1983 SN - 0044-3093 VL - 74 IS - 8 SP - 530 EP - 534 ER - TY - JOUR A1 - Anik, Sabri A1 - Frohberg, Martin G. T1 - Thermodynamics of oxygen in the copper-antimony system at 1473K JF - Erzmetall : Rohstoffgewinnung, Verarbeitung, Recycling, Umwelttechnik Y1 - 1988 SN - 0044-2658 VL - 41 IS - 10 SP - 498 EP - 501 ER - TY - JOUR A1 - Anik, Sabri A1 - Dagsoez, A. K. T1 - Feinbleche schweißen : die Temperaturverteilung in dünnen Stahlblechplatten beim Lichtbogenschweißen JF - Technische Rundschau : TR ; das Schweizer Industrie-Magazin Y1 - 1971 SN - 0040-148X VL - 63 IS - 9 SP - 57 EP - 59 PB - Medtrix Group CY - Basel ER - TY - JOUR A1 - Anik, Sabri A1 - Anik, Salahaddin T1 - Stand der Schweißtechnik in der Türkei JF - Schweißen und Schneiden : Fachzeitschrift für Schweißen und verwandte Verfahren Y1 - 1991 SN - 0036-7184 VL - 43 IS - 3 SP - 142 EP - 145 ER - TY - JOUR A1 - Anik, Sabri T1 - Gespritzte Metallbeschichtungen : Eigenschaften lichtbogengespritzter Stahlschichten in Abhängigkeit von einigen Spritzparametern JF - Technische Rundschau : TR ; das Schweizer Industrie-Magazin Y1 - 1978 SN - 0040-148X VL - 70 IS - 26 SP - 9 EP - 13 PB - Medtrix Group CY - Basel ER - TY - JOUR A1 - Anik, Sabri T1 - Gespritzte Metallschichten : Eigenschaften lichtbogengespritzter Stahlschichten in Abhängigkeit von einigen Spritzparametern JF - Technische Rundschau : TR ; das Schweizer Industrie-Magazin Y1 - 1978 SN - 0040-148X VL - 70 IS - 39 SP - 37 EP - 41 PB - Medtrix Group CY - Basel ER - TY - JOUR A1 - Angermann, Susanne A1 - Günthner, Roman A1 - Hanssen, Henner A1 - Lorenz, Georg A1 - Braunisch, Matthias C. A1 - Steubl, Dominik A1 - Matschkal, Julia A1 - Kemmner, Stephan A1 - Hausinger, Renate A1 - Block, Zenonas A1 - Haller, Bernhard A1 - Heemann, Uwe A1 - Kotliar, Konstantin A1 - Grimmer, Timo A1 - Schmaderer, Christoph T1 - Cognitive impairment and microvascular function in end-stage renal disease JF - International Journal of Methods in Psychiatric Research (MPR) N2 - Objective Hemodialysis patients show an approximately threefold higher prevalence of cognitive impairment compared to the age-matched general population. Impaired microcirculatory function is one of the assumed causes. Dynamic retinal vessel analysis is a quantitative method for measuring neurovascular coupling and microvascular endothelial function. We hypothesize that cognitive impairment is associated with altered microcirculation of retinal vessels. Methods 152 chronic hemodialysis patients underwent cognitive testing using the Montreal Cognitive Assessment. Retinal microcirculation was assessed by Dynamic Retinal Vessel Analysis, which carries out an examination recording retinal vessels' reaction to a flicker light stimulus under standardized conditions. Results In unadjusted as well as in adjusted linear regression analyses a significant association between the visuospatial executive function domain score of the Montreal Cognitive Assessment and the maximum arteriolar dilation as response of retinal arterioles to the flicker light stimulation was obtained. Conclusion This is the first study determining retinal microvascular function as surrogate for cerebral microvascular function and cognition in hemodialysis patients. The relationship between impairment in executive function and reduced arteriolar reaction to flicker light stimulation supports the involvement of cerebral small vessel disease as contributing factor for the development of cognitive impairment in this patient population and might be a target for noninvasive disease monitoring and therapeutic intervention. KW - cerebral small vessel disease KW - cognitive impairment KW - dialysis KW - retinal vessels Y1 - 2022 U6 - https://doi.org/10.1002/mpr.1909 SN - 1049-8931 (Print) SN - 1557-0657 (Online) VL - 31 IS - 2 SP - 1 EP - 10 PB - Wiley ER - TY - JOUR A1 - Anding, Ralf A1 - Tabaza, Ruth A1 - Staat, Manfred A1 - Trenz, Eva A1 - Lohmann, Philipp A1 - Klinge, Uwe A1 - Kirschner-Hermanns, Ruth T1 - Introducing a method of in vitro testing of different anchoring systems used for female incontinence and prolapse surgery JF - BioMed research international Y1 - 2013 SN - 1110-7251 (E-Journal); 2314-6141 (E-Journal); 1110-7243 (Print); 2314-6133 (Print) VL - Vol. 2013 SP - Article ID 401417 ER - TY - JOUR A1 - Amin, Rashid A1 - Temiz Artmann, Aysegül A1 - Artmann, Gerhard A1 - Lazarovici, Philip A1 - Lelkes, Peter I. T1 - Permeability of an In Vitro Model of Blood Brain Barrier (BBB) JF - 13th International Conference on Biomedical Engineering / Lim, Chwee Teck [Ed.] Y1 - 2009 SN - 978-3-540-92841-6 N1 - IFMBE Proceedings ; 23, Track 1 ; ICBME 2008 3–6 December 2008 Singapore SP - 81 EP - 84 ER - TY - JOUR A1 - Altherr, Lena A1 - Leise, Philipp A1 - Pfetsch, Marc E. A1 - Schmitt, Andreas T1 - Algorithmic design and resilience assessment of energy efficient high-rise water supply systems JF - Applied Mechanics and Materials N2 - High-rise water supply systems provide water flow and suitable pressure in all levels of tall buildings. To design such state-of-the-art systems, the consideration of energy efficiency and the anticipation of component failures are mandatory. In this paper, we use Mixed-Integer Nonlinear Programming to compute an optimal placement of pipes and pumps, as well as an optimal control strategy.Moreover, we consider the resilience of the system to pump failures. A resilient system is able to fulfill a predefined minimum functionality even though components fail or are restricted in their normal usage. We present models to measure and optimize the resilience. To demonstrate our approach, we design and analyze an optimal resilient decentralized water supply system inspired by a real-life hotel building. KW - MINLP KW - Buffering Capacity KW - Uncertainty KW - Water Supply Networks KW - Booster Stations Y1 - 2018 U6 - https://doi.org/10.4028/www.scientific.net/AMM.885.211 SN - 1662-7482 VL - 885 SP - 211 EP - 223 PB - Trans Tech Publications CY - Bäch ER -