TY  - JOUR
A1  - Bäcker, Matthias
A1  - Koch, Claudia
A1  - Eiben, Sabine
A1  - Geiger, Fania
A1  - Eber, Fabian
A1  - Gliemann, Hartmut
A1  - Poghossian, Arshak
A1  - Wege, Christina
A1  - Schöning, Michael Josef
T1  - Tobacco mosaic virus as enzyme nanocarrier for electrochemical biosensors
JF  - Sensors and Actuators B: Chemical
N2  - The conjunction of (bio-)chemical recognition elements with nanoscale biological building blocks such as virus particles is considered as a very promising strategy for the creation of biohybrids opening novel opportunities for label-free biosensing. This work presents a new approach for the development of biosensors using tobacco mosaic virus (TMV) nanotubes or coat proteins (CPs) as enzyme nanocarriers. Sensor chips combining an array of Pt electrodes loaded with glucose oxidase (GOD)-modified TMV nanotubes or CP aggregates were used for amperometric detection of glucose as a model system for the first time. The presence of TMV nanotubes or CPs on the sensor surface allows binding of a high amount of precisely positioned enzymes without substantial loss of their activity, and may also ensure accessibility of their active centers for analyte molecules. Specific and efficient immobilization of streptavidin-conjugated GOD ([SA]-GOD) complexes on biotinylated TMV nanotubes or CPs was achieved via bioaffinity binding. These layouts were tested in parallel with glucose sensors with adsorptively immobilized [SA]-GOD, as well as [SA]-GOD crosslinked with glutardialdehyde, and came out to exhibit superior sensor performance. The achieved results underline a great potential of an integration of virus/biomolecule hybrids with electronic transducers for future applications in biosensorics and biochips.
Y1  - 2017
U6  - https://doi.org/10.1016/j.snb.2016.07.096
SN  - 0925-4005
VL  - 238
SP  - 716
EP  - 722
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Lopes, Pedro
A1  - Leandro, Jorge
A1  - Carvalho, Rita F.
A1  - Bung, Daniel Bernhard
T1  - Alternating skimming flow over a stepped spillway
JF  - Environmental Fluid Mechanics
Y1  - 2017
U6  - https://doi.org/10.1007/s10652-016-9484-x
SN  - 1573-1510
VL  - 17
IS  - 2
SP  - 303
EP  - 322
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Hackl, M.
A1  - Andermahr, J.
A1  - Staat, Manfred
A1  - Bremer, I.
A1  - Borggrefe, J.
A1  - Prescher, A.
A1  - Müller, L. P.
A1  - Wegmann, K.
T1  - Suture button reconstruction of the central band of the interosseous membrane in Essex-Lopresti lesions: a comparative biomechanical investigation
JF  - The Journal of Hand Surgery (European Volume)
Y1  - 2017
U6  - https://doi.org/10.1177/1753193416665943
SN  - 2043-6289 (Online)
SN  - 1753-1934 (Print)
VL  - 42
IS  - 4
SP  - 370
EP  - 376
PB  - Sage
CY  - London
ER  - 
TY  - JOUR
A1  - Kerres, Karsten
A1  - Siekmann, Marko
T1  - Wie kommuniziere ich prognosegestützte Instandhaltungsstrategien erfolgreich in politischen Entscheidungsgremien?
JF  - 3 R. Fachzeitschrift für sichere und effiziente Rohleitungssysteme
Y1  - 2018
SN  - 2191-9798
IS  - 12
SP  - 47
EP  - 51
PB  - Vulkan-Verl.
CY  - Essen
ER  - 
TY  - JOUR
A1  - Bäcker, M.
A1  - Rakowski, D.
A1  - Krappen, E.
A1  - Schöning, Michael Josef
T1  - Reinigungsprozesse in der Lebensmittelindustrie. Entwicklung eines Demonstrators zur Überwachung
JF  - GIT Labor-Fachzeitschrift
Y1  - 2017
SN  - 0016-3538
VL  - 61
IS  - 8
SP  - 26
EP  - 28
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Dikta, Gerhard
T1  - Semi-parametric random censorship models
JF  - From Statistics to Mathematical Finance : Festschrift in Honour of Winfried Stute
Y1  - 2017
SN  - 978-3-319-50986-0
U6  - https://doi.org/10.1007/978-3-319-50986-0_3
SP  - 43
EP  - 56
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Wilke, Thomas
T1  - Newly found plans for the chapel of the Holy Shroud
JF  - Studi Piemontesi
Y1  - 2017
SN  - 0392-7261
VL  - XLVI
IS  - 1
SP  - 75
EP  - 85
ER  - 
TY  - JOUR
A1  - Wilke, Thomas
T1  - [Rezension zu:] Deutsch, Kristina: Jean Marot. Un graveur d'architecture à l'époque de Louis XIV. (= Ars et Scientia; 12), Berlin; Boston 2015.
JF  - ArtHist.net
Y1  - 2017
ER  - 
TY  - JOUR
A1  - Wilson, Ian D.
A1  - Wilson, Claire E.
A1  - Scheer, Nico
A1  - Dickie, A.P.
A1  - Schreiter, K.
A1  - Wilson, E. M.
A1  - Riley, R. J.
A1  - Wehr, R.
A1  - Bial, J.
T1  - The Pharmacokinetics and Metabolism of Lumiracoxib in Chimeric Humanized and Murinized FRG Mice
JF  - Biochemical pharmacology
Y1  - 2017
U6  - https://doi.org/10.1016/j.bcp.2017.03.015
SN  - 1873-2968
VL  - Volume 135
SP  - 139
EP  - 150
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Savitskaya, I. S.
A1  - Kistaubayeva, A. S.
A1  - Digel, Ilya
A1  - Shokatayeva, D. H.
T1  - Physicochemical and Antibacterial Properties of Composite Films Based on Bacterial Cellulose and Chitosan for Wound Dressing Materials
JF  - Eurasian Chemico-Technological Journal
Y1  - 2017
U6  - https://doi.org/10.18321/ectj670
SN  - 2522-4867
VL  - 19
IS  - 3
SP  - 255
EP  - 264
ER  -