TY - JOUR A1 - Zhubanova, А. A1 - Mansurov, Z.A. A1 - Digel, Ilya A1 - Saviskaya, I.S. A1 - Akimbekov, N.Sh. T1 - Designing of Heterogeneous Nanobiocomposites for Biotechnology JF - KazNU Bulletin. Biology series Y1 - 2013 SN - 1563-0218 VL - 59 IS - No 3/1 SP - 89 EP - 93 ER - TY - JOUR A1 - Werner, Frederik A1 - Wagner, Torsten A1 - Yoshinobu, Tatsuo A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Frequency behaviour of light-addressable potentiometric sensors JF - Physica Status Solidi (A) N2 - Light-addressable potentiometric sensors (LAPS) are semiconductor-based potentiometric sensors, with the advantage to detect the concentration of a chemical species in a liquid solution above the sensor surface in a spatially resolved manner. The addressing is achieved by a modulated and focused light source illuminating the semiconductor and generating a concentration-depending photocurrent. This work introduces a LAPS set-up that is able to monitor the electrical impedance in addition to the photocurrent. The impedance spectra of a LAPS structure, with and without illumination, as well as the frequency behaviour of the LAPS measurement are investigated. The measurements are supported by electrical equivalent circuits to explain the impedance and the LAPS-frequency behaviour. The work investigates the influence of different parameters on the frequency behaviour of the LAPS. Furthermore, the phase shift of the photocurrent, the influence of the surface potential as well as the changes of the sensor impedance will be discussed. Y1 - 2013 U6 - http://dx.doi.org/10.1002/pssa.201200929 SN - 1521-396X ; 0031-8965 VL - 210 IS - 5 SP - 884 EP - 891 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Werner, Frederik A1 - Takenaga, Shoko A1 - Taki, Hidenori A1 - Sawada, Kazuaki A1 - Schöning, Michael Josef T1 - Comparison of label-free ACh-imaging sensors based on CCD and LAPS JF - Sensors and Actuators B: Chemical (2012) N2 - Semiconductor-based chemical imaging sensors, like the light-addressable potentiometric sensor (LAPS) or the pH-imaging sensor based on a charge-coupled device (CCD), are becoming a powerful tool for label-free imaging of biological phenomena. We have proposed a polyion-based enzymatic membrane to develop an acetylcholine (ACh) imaging sensor for neural cell-activity observations. In this study, a CCD-type ACh-imaging sensor and a LAPS-type ACh-imaging sensor were fabricated and the prospect of both sensors was clarified by making a comparison of their basic characteristics. Y1 - 2013 SN - 0925-4005 VL - 177 SP - 745 EP - 752 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Tran, Thanh Ngoc A1 - Staat, Manfred T1 - An Edge-Based Smoothed Finite Element Method for Primal-Dual Shakedown Analysis of Structures Under Uncertainties JF - Limit State of Materials and Structures : Direct Methods 2. Saxcé, Géry de (Hrsg.) Y1 - 2013 SN - 978-94-007-5424-9 SP - 89 EP - 102 PB - Springer CY - Dordrecht ER - TY - JOUR A1 - Stulpe, Werner T1 - From the attempt of certain classical reformulations of quantum mechanics to quasi-probability representations JF - Journal of mathematical physics N2 - The concept of an injective affine embedding of the quantum states into a set of classical states, i.e., into the set of the probability measures on some measurable space, as well as its relation to statistically complete observables is revisited, and its limitation in view of a classical reformulation of the statistical scheme of quantum mechanics is discussed. In particular, on the basis of a theorem concerning a non-denseness property of a set of coexistent effects, it is shown that an injective classical embedding of the quantum states cannot be supplemented by an at least approximate classical description of the quantum mechanical effects. As an alternative approach, the concept of quasi-probability representations of quantum mechanics is considered. Y1 - 2013 U6 - http://dx.doi.org/10.1063/1.4861939 SN - 1089-7658 (Online) SN - 0022-2488 (Print) VL - 55 IS - 1 PB - American Institute of Physics ER - TY - JOUR A1 - Staat, Manfred T1 - Limit and shakedown analysis under uncertainty JF - International journal of computational methods : IJCM Y1 - 2013 SN - 0219-8762 SP - Publ. online PB - World Scientific Publishing CY - Singapore ER - TY - JOUR A1 - Schusser, Sebastian A1 - Menzel, S. A1 - Bäcker, Matthias A1 - Leinhos, Marcel A1 - Poghossian, Arshak A1 - Wagner, P. A1 - Schöning, Michael Josef T1 - Degradation of thin poly(lactic acid) films: characterization by capacitance-voltage, atomic force microscopy, scanning electron microscopy and contact-angle measurements JF - Electrochimica Acta Y1 - 2013 SN - 1873-3859 (E-Journal); 0013-4686 (Print) VL - Vol. 113 SP - 779 EP - 784 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Schusser, Sebastian A1 - Leinhos, Marcel A1 - Bäcker, Matthias A1 - Poghossian, Arshak A1 - Wagner, Patrick A1 - Schöning, Michael Josef T1 - Impedance spectroscopy: A tool for real-time in situ monitoring of the degradation of biopolymers JF - Physica Status Solidi (A) N2 - Investigation of the degradation kinetics of biodegradable polymers is essential for the development of implantable biomedical devices with predicted biodegradability. In this work, an impedimetric sensor has been applied for real-time and in situ monitoring of degradation processes of biopolymers. The sensor consists of two platinum thin-film electrodes covered by a polymer film to be studied. The benchmark biomedical polymer poly(D,L-lactic acid) (PDLLA) was used as a model system. PDLLA films were deposited on the sensor structure from a polymer solution by using the spin-coating method. The degradation kinetics of PDLLA films have been studied in alkaline solutions of pH 9 and 12 by means of an impedance spectroscopy (IS) method. Any changes in a polymer capacitance/resistance induced by water uptake and/or polymer degradation will modulate the global impedance of the polymer-covered sensor that can be used as an indicator of the polymer degradation. The degradation rate can be evaluated from the time-dependent impedance spectra. As expected, a faster degradation has been observed for PDLLA films exposed to pH 12 solution. Y1 - 2013 U6 - http://dx.doi.org/10.1002/pssa.201200941 SN - 1521-396X ; 0031-8965 VL - 210 IS - 5 SP - 905 EP - 910 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Reisert, Steffen A1 - Schneider, Benno A1 - Geissler, Hanno A1 - Gompel, Matthias van A1 - Wagner, Patrick A1 - Schöning, Michael Josef T1 - Multi-sensor chip for the investigation of different types of metal oxides for the detection of H2O2 in the ppm range JF - physica status solidi (a) N2 - In this work, a multi-sensor chip for the investigation of the sensing properties of different types of metal oxides towards hydrogen peroxide in the ppm range is presented. The fabrication process and physical characterization of the multi-sensor chip are described. Pure SnO2 and WO3 as well as Pd- and Pt-doped SnO2 films are characterized in terms of their sensitivity to H2O2. The sensing films have been prepared by drop-coating of water-dispensed nano-powders. A physical characterization, including scanning electron microscopy and X-ray diffraction analysis of the deposited metal-oxide films, was done. From the measurements in hydrogen peroxide atmosphere, it could be shown, that all of the tested metal oxide films are suitable for the detection of H2O2 in the ppm range. The highest sensitivity and reproducibility was achieved using Pt-doped SnO2. Calibration plot of a SnO2, WO3, Pt-, and Pd-doped SnO2 gas sensor for H2O2 concentrations in the ppm range. Y1 - 2013 SN - 1862-6319 VL - 210 IS - 5 SP - 898 EP - 904 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Reisert, Steffen A1 - Geissler, Hanno A1 - Flörke, Rudolf A1 - Weiler, Christian A1 - Wagner, Patrick A1 - Schöning, Michael Josef T1 - Characterisation of aseptic sterilisation processes using an electronic nose JF - International journal of nanotechnology Y1 - 2013 SN - 1475-7435 (Print) 7141-8151 (Online) VL - Vol. 10 IS - No. 5-7 SP - 470 EP - 484 PB - Inderscience Enterprises CY - Genève ER - TY - JOUR A1 - Poghossian, Arshak A1 - Weil, M. A1 - Cherstvy, A. G. A1 - Schöning, Michael Josef T1 - Electrical monitoring of polyelectrolyte multilayer formation by means of capacitive field-effect devices JF - Analytical and bioanalytical chemistry N2 - The semiconductor field-effect platform represents a powerful tool for detecting the adsorption and binding of charged macromolecules with direct electrical readout. In this work, a capacitive electrolyte–insulator–semiconductor (EIS) field-effect sensor consisting of an Al-p-Si-SiO2 structure has been applied for real-time in situ electrical monitoring of the layer-by-layer formation of polyelectrolyte (PE) multilayers (PEM). The PEMs were deposited directly onto the SiO2 surface without any precursor layer or drying procedures. Anionic poly(sodium 4-styrene sulfonate) and cationic weak polyelectrolyte poly(allylamine hydrochloride) have been chosen as a model system. The effect of the ionic strength of the solution, polyelectrolyte concentration, number and polarity of the PE layers on the characteristics of the PEM-modified EIS sensors have been studied by means of capacitance–voltage and constant-capacitance methods. In addition, the thickness, surface morphology, roughness and wettabilityof the PE mono- and multilayers have been characterised by ellipsometry, atomic force microscopy and water contact-angle methods, respectively. To explain potential oscillations on the gate surface and signal behaviour of the capacitive field-effect EIS sensor modified with a PEM, a simplified electrostatic model that takes into account the reduced electrostatic screening of PE charges by mobile ions within the PEM has been proposed and discussed. Y1 - 2013 U6 - http://dx.doi.org/10.1007/s00216-013-6951-9 SN - 1432-1130 ; 1618-2642 VL - 405 IS - 20 SP - 6425 EP - 6436 PB - Springer CY - Berlin ER - TY - JOUR A1 - Pham, Phu Tinh A1 - Staat, Manfred T1 - An Upper Bound Algorithm for Limit and Shakedown Analysis of Bounded Linearly Kinematic Hardening Structures JF - Limit State of Materials and Structures : Direct Methods 2. Saxcé, Géry de (Hrsg.) Y1 - 2013 SN - 978-94-007-5424-9 SP - 71 EP - 87 PB - Springer CY - Dordrecht ER - TY - JOUR A1 - Murib, M. S. A1 - Grinsven, B. van A1 - Grieten, L. A1 - Janssens, S. D. A1 - Vermeeren, V. A1 - Eersels, K. A1 - Broeders, J. A1 - Ameloot, M. A1 - Michiels, L. A1 - Ceuninck, W. De A1 - Haenen, K. A1 - Schöning, Michael Josef A1 - Wagner, Patrick T1 - Electronic monitoring of chemical DNA denaturation on nanocrystalline diamond electrodes with different molarities and flow rates JF - Physica Status Solidi (A). Vol. 210 (2013), iss. 5 Y1 - 2013 SN - 0031-8965 SP - 911 EP - 917 PB - Wiley-VCH CY - Berlin ER - TY - JOUR A1 - Murgan, Ilina A1 - Beyer, Sonja A1 - Kotliar, Konstantin A1 - Weber, Lutz A1 - Bechtold-Dalla Pozza, Susanne A1 - Dalla Pozza, Robert A1 - Wegner, Aharon A1 - Sitnikova, Diana A1 - Stock, Konrad A1 - Heemann, Uwe A1 - Schmaderer, Christoph A1 - Baumann, M. T1 - Arterial and Retinal Vascular Changes in Hypertensive and Prehypertensive Adolescents JF - American Journal of Hypertension Y1 - 2013 SN - 1941-7225 VL - 26 IS - 3 SP - 400 EP - 408 PB - Oxford University Press CY - Oxford ER - TY - JOUR A1 - Miyamoto, Ko-ichiro A1 - Ichimura, Hiroki A1 - Wagner, Torsten A1 - Schöning, Michael Josef A1 - Yoshinobu, Tatsuo T1 - Chemical imaging of the concentration profile of ion diffusion in a microfluidic channel JF - Sensors and actuators. B: Chemical N2 - The chemical imaging sensor is a device to visualize the spatial distribution of chemical species based on the principle of LAPS (light-addressable potentiometric sensor), which is a field-effect chemical sensor based on semiconductor. In this study, the chemical imaging sensor has been applied to investigate the ion profile of laminar flows in a microfluidic channel. The chemical images (pH maps) were collected in a Y-shaped microfluidic channel while injecting HCl and NaCl solutions into two branches. From the chemical images, it was clearly observed that the injected solutions formed laminar flows in the channel. In addition, ion diffusion across the laminar flows was observed, and the diffusion coefficient could be derived by fitting the pH profiles to the Fick's equation. Y1 - 2013 U6 - http://dx.doi.org/10.1016/j.snb.2013.04.057 SN - 1873-3077 (E-Journal); 0925-4005 (Print) N1 - Part of special issue "Selected Papers from the 26th European Conference on Solid-State Transducers" VL - 189 SP - 240 EP - 245 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Miyamoto, Ko-ichiro A1 - Hirayama, Yuji A1 - Wagner, Torsten A1 - Schöning, Michael Josef A1 - Yoshinobu, Tatsuo T1 - Visualization of enzymatic reaction in a microfluidic channel using chemical imaging sensor JF - Electrochimica acta Y1 - 2013 SN - 1873-3859 (E-Journal); 0013-4686 (Print) SP - Publ. online PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Micili, Serap C. A1 - Valter, Markus A1 - Oflaz, Hakan A1 - Ozogul, Candan A1 - Linder, Peter A1 - Föckler, Nicole A1 - Artmann, Gerhard A1 - Digel, Ilya A1 - Temiz Artmann, Aysegül T1 - Optical coherence tomography : a potential tool to predict premature rupture of fetal membranes JF - Proceedings of the Institution of Mechanical Engineers. Part H : Journal of engineering in medicine Y1 - 2013 SN - 0046-2039 (Print) ; 2041-3033 (E-Journal) VL - Vol. 227 IS - No. 4 SP - 393 EP - 401 PB - Sage CY - London ER - TY - JOUR A1 - Linden, A. A1 - Fischöder, M. A1 - Laack, Walter van A1 - Staat, Manfred T1 - Einschränkung von Taluskippung und -vorschub durch Sprunggelenkorthesen nach fibularer Bandruptur JF - OUP Zeitschrift für die orthopädische und unfallchirurgische Praxis N2 - Die fibulare Bandruptur zählt zu einer der am häufigsten auftretenden Verletzungen des Bewegungsapparats. In den meisten Fällen wird heute die konservativ frühfunktionelle Therapie mit Sprunggelenkorthesen allgemein bevorzugt. Im Rahmen der vorliegenden Studie wurden 14 verschiedene Sprunggelenkorthesen im Hinblick auf ihre Einschränkung von Taluskippung und Talusvorschub untersucht. Zur Simulation einer fibularen Bandruptur wurde ein Unterschenkelmodell aus Holz mit Fußteil, mit angelegten Orthesen in einen Scheuba-Halteapparat eingespannt und mit 150 N seitlich sowie anterior-posterior belastet. Anhand der erstellten "gehaltenen" Röntgenaufnahmen konnten Taluskippung und Talusvorschub jeder einzelnen Orthese eindeutig bestimmt werden. Die meisten Orthesen erreichten zufriedenstellende Ergebnisse. Es stellte sich heraus, dass vor allem eine eng anliegende, im Gelenkbereich anatomisch angepasste Form vorteilhaft zu sein scheint. N2 - The ankle sprain is actually one of the most common injuries. Nowadays the conservative pre-functional therapy with ankle braces is generally preferred. In the present study 14 different ankle braces were tested with regard to their ability to constrict the talar tilt and anterior drawer displacement. As part of the tests a wooden model of a foot was used in order to simulate an ankle sprain. This model was clamped in a Scheuba-device with different ankle braces and a force of 150 N was applied to it. The stress radiographs showed different talar tilts and anterior drawers of each brace. Most ankle braces achieved a satisfying result. It has become obvious that a tight fitting and an anatomically designed shape seem to be favourable. T2 - Constraint of talar tilt and anterior drawer by different ankle braces after the rupture of fibular ligaments KW - Sprunggelenkorthesen KW - fibulare Bandruptur KW - Distorsion des oberen Sprunggelenks KW - ankle sprain KW - rupture of the fibular ligament KW - ankle braces Y1 - 2013 SN - 2193-5785 U6 - http://dx.doi.org/10.3238/oup.2013.0306-0309 VL - 2 IS - 6 SP - 306 EP - 309 PB - Deutscher Ärzte-Verl. CY - Köln ER - TY - JOUR A1 - Laack, Walter van T1 - The genetic code should be seen as a positioning code JF - British journal of arts and social sciences. Vol. 14 (2013), No. 1 Y1 - 2013 SN - 2046-9578 SP - 93 EP - 97 ER - TY - JOUR A1 - Laack, Walter van T1 - Why natural constants are as they are JF - British journal of arts and social sciences Y1 - 2013 SN - 2046-9578 (E-Journal) VL - Vol. 15 IS - Nr. 2 SP - 198 EP - 203 PB - BritishJournal Publ. Inc CY - London ER -