TY - JOUR A1 - Poghossian, Arshak A1 - Jablonski, Melanie A1 - Molinnus, Denise A1 - Wege, Christina A1 - Schöning, Michael Josef T1 - Field-Effect Sensors for Virus Detection: From Ebola to SARS-CoV-2 and Plant Viral Enhancers JF - Frontiers in Plant Science N2 - Coronavirus disease 2019 (COVID-19) is a novel human infectious disease provoked by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Currently, no specific vaccines or drugs against COVID-19 are available. Therefore, early diagnosis and treatment are essential in order to slow the virus spread and to contain the disease outbreak. Hence, new diagnostic tests and devices for virus detection in clinical samples that are faster, more accurate and reliable, easier and cost-efficient than existing ones are needed. Due to the small sizes, fast response time, label-free operation without the need for expensive and time-consuming labeling steps, the possibility of real-time and multiplexed measurements, robustness and portability (point-of-care and on-site testing), biosensors based on semiconductor field-effect devices (FEDs) are one of the most attractive platforms for an electrical detection of charged biomolecules and bioparticles by their intrinsic charge. In this review, recent advances and key developments in the field of label-free detection of viruses (including plant viruses) with various types of FEDs are presented. In recent years, however, certain plant viruses have also attracted additional interest for biosensor layouts: Their repetitive protein subunits arranged at nanometric spacing can be employed for coupling functional molecules. If used as adapters on sensor chip surfaces, they allow an efficient immobilization of analyte-specific recognition and detector elements such as antibodies and enzymes at highest surface densities. The display on plant viral bionanoparticles may also lead to long-time stabilization of sensor molecules upon repeated uses and has the potential to increase sensor performance substantially, compared to conventional layouts. This has been demonstrated in different proof-of-concept biosensor devices. Therefore, richly available plant viral particles, non-pathogenic for animals or humans, might gain novel importance if applied in receptor layers of FEDs. These perspectives are explained and discussed with regard to future detection strategies for COVID-19 and related viral diseases. Y1 - 2020 U6 - http://dx.doi.org/10.3389/fpls.2020.598103 VL - 11 IS - Article 598103 SP - 1 EP - 14 PB - Frontiers CY - Lausanne ER - TY - JOUR A1 - Götten, Falk A1 - Havermann, Marc A1 - Braun, Carsten A1 - Marino, Matthew A1 - Bil, Cees T1 - Improved Form Factor for Drag Estimation of Fuselages with Various Cross Sections JF - Journal of Aircraft N2 - The paper presents an aerodynamic investigation of 70 different streamlined bodies with fineness ratios ranging from 2 to 10. The bodies are chosen to idealize both unmanned and small manned aircraft fuselages and feature cross-sectional shapes that vary from circular to quadratic. The study focuses on friction and pressure drag in dependency of the individual body’s fineness ratio and cross section. The drag forces are normalized with the respective body’s wetted area to comply with an empirical drag estimation procedure. Although the friction drag coefficient then stays rather constant for all bodies, their pressure drag coefficients decrease with an increase in fineness ratio. Referring the pressure drag coefficient to the bodies’ cross-sectional areas shows a distinct pressure drag minimum at a fineness ratio of about three. The pressure drag of bodies with a quadratic cross section is generally higher than for bodies of revolution. The results are used to derive an improved form factor that can be employed in a classic empirical drag estimation method. The improved formulation takes both the fineness ratio and cross-sectional shape into account. It shows superior accuracy in estimating streamlined body drag when compared with experimental data and other form factor formulations of the literature. Y1 - 2020 U6 - http://dx.doi.org/10.2514/1.C036032 SN - 1533-3868 SP - 1 EP - 13 PB - AIAA CY - Reston, Va. ER - TY - BOOK A1 - Lohse, Wolfram A1 - Laumann, Jörg A1 - Wolf, Christian T1 - Stahlbau 2 Y1 - 2020 SN - 978-3-8348-2116-4 SN - 978-3-8348-1511-8 U6 - http://dx.doi.org/10.1007/978-3-8348-2116-4 PB - Springer Vieweg CY - Wiesbaden ET - 21., vollst. akt. und überarb. Aufl. ER - TY - JOUR A1 - Gossmann, Matthias A1 - Thomas, Ulrich A1 - Horváth, András A1 - Dragicevic, Elena A1 - Stoelzle-Feix, Sonja A1 - Jung, Alexander A1 - Raman, Aravind Hariharan A1 - Staat, Manfred A1 - Linder, Peter T1 - A higher-throughput approach to investigate cardiac contractility in vitro under physiological mechanical conditions JF - Journal of Pharmacological and Toxicological Methods Y1 - 2020 U6 - http://dx.doi.org/10.1016/j.vascn.2020.106843 VL - 105 IS - Article 106843 PB - Elsevier CY - New York, NY ER - TY - CHAP A1 - Fateri, Miranda A1 - Gebhardt, Andreas T1 - Introduction to Additive Manufacturing T2 - 3D Printing of Optical Components N2 - Additive manufacturing (AM) works by creating objects layer by layer in a manner similar to a 2D printer with the “printed” layers stacked on top of each other. The layer-wise manufacturing nature of AM enables fabrication of freeform geometries which cannot be fabricated using conventional manufacturing methods as a one part. Depending on how each layer is created and bonded to the adjacent layers, different AM methods have been developed. In this chapter, the basic terms, common materials, and different methods of AM are described, and their potential applications are discussed. KW - Additive manufacturing KW - 3D printing KW - Digital manufacturing KW - Rapid prototyping KW - Rapid manufacturing Y1 - 2020 SN - 978-3-030-58960-8 U6 - http://dx.doi.org/10.1007/978-3-030-58960-8_1 SP - 1 EP - 22 PB - Springer CY - Cham ER - TY - CHAP A1 - Chavez Bermudez, Victor Francisco A1 - Wollert, Jörg T1 - Arduino based Framework for Rapid Application Development of a Generic IO-Link interface T2 - Kommunikation und Bildverarbeitung in der Automation N2 - The implementation of IO-Link in the automation industry has increased over the years. Its main advantage is it offers a digital point-to-point plugand-play interface for any type of device or application. This simplifies the communication between devices and increases productivity with its different features like self-parametrization and maintenance. However, its complete potential is not always used. The aim of this paper is to create an Arduino based framework for the development of generic IO-Link devices and increase its implementation for rapid prototyping. By generating the IO device description file (IODD) from a graphical user interface, and further customizable options for the device application, the end-user can intuitively develop generic IO-Link devices. The peculiarity of this framework relies on its simplicity and abstraction which allows to implement any sensor functionality and virtually connect any type of device to an IO-Link master. This work consists of the general overview of the framework, the technical background of its development and a proof of concept which demonstrates the workflow for its implementation. Y1 - 2020 SN - 978-3-662-59895-5 SN - 978-3-662-59894-8 U6 - http://dx.doi.org/10.1007/978-3-662-59895-5_2 N1 - Teil der Buchserie "Technologien für die intelligente Automation" (TIA,volume 12) SP - 21 EP - 33 PB - Springer Vieweg CY - Berlin ER - TY - JOUR A1 - Gazda, Quentin A1 - Maurischat, Andreas T1 - Special functions and Gauss-Thakur sums in higher rank and dimension Y1 - 2020 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Stulpe, Werner T1 - Pairwise coexistence of effects versus coexistence JF - Journal of Physics: Conference Series Y1 - 2020 U6 - http://dx.doi.org/10.1088/1742-6596/1638/1/012004 SN - 1742-6596 VL - 1638 IS - 012004 SP - 1 EP - 21 PB - IOP CY - Bristol ER - TY - CHAP A1 - Frantz, Cathy A1 - Binder, Matthias A1 - Busch, Konrad A1 - Ebert, Miriam A1 - Heinrich, Andreas A1 - Kaczmarkiewicz, Nadine A1 - Schlögl-Knothe, Bärbel A1 - Kunze, Tobias A1 - Schuhbauer, Christian A1 - Stetka, Markus A1 - Schwager, Christian A1 - Spiegel, Michael A1 - Teixeira Boura, Cristiano José A1 - Bauer, Thomas A1 - Bonk, Alexander A1 - Eisen, Stefan A1 - Funck, Bernhard T1 - Basic Engineering of a High Performance Molten Salt Tower Receiver System T2 - Solar Paces 2020 Y1 - 2020 SP - 1 EP - 10 ER - TY - CHAP A1 - Iomdina, Elena N. A1 - Kiseleva, Anna A. A1 - Kotliar, Konstantin A1 - Luzhnov, Petr V. T1 - Quantification of Choroidal Blood Flow Using the OCT-A System Based on Voxel Scan Processing T2 - 2020 International Conference on Biomedical Innovations and Applications (BIA) Y1 - 2020 SN - 978-1-7281-7073-2 U6 - http://dx.doi.org/10.1109/BIA50171.2020.9244511 SP - 41 EP - 44 ER -