TY - JOUR A1 - Jordan, Sabine D. A1 - Krüger, Markus A1 - Willmes, Diana M. A1 - Redemann, Nora A1 - Wunderlich, F. Thomas A1 - Brönneke, Hella S. A1 - Merkwirth, Carsten A1 - Kashkar, Hamid A1 - Olkkonen, Vesa M. A1 - Böttger, Thomas A1 - Braun, Thomas A1 - Seibler, Jost A1 - Brüning, Jens C. T1 - Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism JF - Nature Cell Biology N2 - The contribution of altered post-transcriptional gene silencing to the development of insulin resistance and type 2 diabetes mellitus so far remains elusive. Here, we demonstrate that expression of microRNA (miR)-143 and 145 is upregulated in the liver of genetic and dietary mouse models of obesity. Induced transgenic overexpression of miR-143, but not miR-145, impairs insulin-stimulated AKT activation and glucose homeostasis. Conversely, mice deficient for the miR-143–145 cluster are protected from the development of obesity-associated insulin resistance. Quantitative-mass-spectrometry-based analysis of hepatic protein expression in miR-143-overexpressing mice revealed miR-143-dependent downregulation of oxysterol-binding-protein-related protein (ORP) 8. Reduced ORP8 expression in cultured liver cells impairs the ability of insulin to induce AKT activation, revealing an ORP8-dependent mechanism of AKT regulation. Our experiments provide direct evidence that dysregulated post-transcriptional gene silencing contributes to the development of obesity-induced insulin resistance, and characterize the miR-143–ORP8 pathway as a potential target for the treatment of obesity-associated diabetes. Y1 - 2011 U6 - https://doi.org/10.1038/ncb2211 SN - 1465-7392 VL - 13 IS - 4 SP - 434 EP - 446 PB - Nature CY - New York ER - TY - JOUR A1 - Kallweit, Stephan A1 - Korculanin, O. A1 - Fröhlig, F. A1 - Gabi, M. A1 - Mattern, P. T1 - Photogrammetrische Rekonstruktion von Partikelpositionen mittels Rückprojektion für 3D-PIV JF - Lasermethoden in der Strömungsmesstechnik : 19. Fachtagung, 6. - 8. September 2011, Ilmenau ; [Tagungsband enthält ... Beiträge, die anlässlich der 19. Fachtagaung "Lasermethoden in der Strömungsmesstechnik" ... vorgetragen und diskutiert wurden] / veranst. von der Deutschen Gesellschaft für Laser-Anemometrie GALA e.V. Hrsg. A. Thess... Y1 - 2011 SN - 978-3-9805613-7-2 N1 - Fachtagung Lasermethoden in der Strömungsmesstechnik <19, 2011, Ilmenau> ; Deutsche Gesellschaft für Laser-Anemometrie SP - 28/1 EP - 28/6 PB - Dt. Ges. für Laser-AnemometrieGALA e. V. CY - Karlsruhe ER - TY - JOUR A1 - Karamanidis, Kiros A1 - Albracht, Kirsten A1 - Braunstein, Bjoern A1 - Catala, Maria Moreno A1 - Goldmann, Jan-Peter A1 - Brüggemann, Gert-Peter T1 - Lower leg musculoskeletal geometry and sprint performance JF - Gait and Posture N2 - The purpose of this study was to investigate whether sprint performance is related to lower leg musculoskeletal geometry within a homogeneous group of highly trained 100-m sprinters. Using a cluster analysis, eighteen male sprinters were divided into two groups based on their personal best (fast: N = 11, 10.30 ± 0.07 s; slow: N = 7, 10.70 ± 0.08 s). Calf muscular fascicle arrangement and Achilles tendon moment arms (calculated by the gradient of tendon excursion versus ankle joint angle) were analyzed for each athlete using ultrasonography. Achilles tendon moment arm, foot and ankle skeletal geometry, fascicle arrangement as well as the ratio of fascicle length to Achilles tendon moment arm showed no significant (p > 0.05) correlation with sprint performance, nor were there any differences in the analyzed musculoskeletal parameters between the fast and slow sprinter group. Our findings provide evidence that differences in sprint ability in world-class athletes are not a result of differences in the geometrical design of the lower leg even when considering both skeletal and muscular components. Y1 - 2011 U6 - https://doi.org/10.1016/j.gaitpost.2011.03.009 SN - 0966-6362 VL - 34 IS - 1 SP - 138 EP - 141 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Kern, Alexander A1 - Scheibe, Klaus T1 - Die neuen internationalen Blitzschutz-Standards der Reihe IEC 62305:2010 : Überblick und Stand der Umsetzung in die nationale Normenreihe DIN EN 62305 JF - 9. VDE/ABB-Blitzschutztagung : Vorträge der 9. VDE/ABB-Fachtagung vom 27. bis 28. Oktober 2011 in Neu-Ulm / Veranst.: Ausschuss für Blitzschutz und Blitzforschung (ABB) im VDE Verband der Elektrotechnik Elektronik Informationstechnik e.V. Wiss. Tagungsleitung: K. Stimper Y1 - 2011 SN - 978-3-8007-3380-4 N1 - VDE/ABB-Blitzschutztagung ; (9 ; 2011.10.27-28 ; Neu-Ulm) SP - 7 EP - 12 PB - VDE-Verl. CY - Berlin ER - TY - JOUR A1 - Kern, Alexander A1 - Schelthoff, Christof A1 - Mathieu, Moritz T1 - Probability of lightning strikes to air-terminations of structures using the electro-geometrical model theory and the statistics of lightning current parameters JF - Atmospheric Research. 104 (2011) Y1 - 2011 SN - 0169-8095 N1 - Article in Press PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Kern, Alexander A1 - Schelthoff, Christof A1 - Mathieu, Moritz T1 - Detaillierte Berechnung der Einfangwirksamkeiten von Fangeinrichtungen mit einem dynamischen elektro-geometrischen Modell - Detailed calculation of the interception efficiencies for airtermination systems using a dynamic electro-geometrical model Y1 - 2011 N1 - 9. VDE/ABB-Blitzschutztagung, Neu-Ulm 2011 SP - 1 EP - 5 ER - TY - JOUR A1 - Kern, Alexander A1 - Schelthoff, Christof A1 - Mathieu, Moritz T1 - Calculation of interception efficiencies for airterminations using a dynamic electro-geometrical model Y1 - 2011 N1 - XI International Symposium on Lightning Protection (SIPDA), Fortaleza (Brasilien), 2011. SP - 1 EP - 6 PB - IEEE CY - New York ER - TY - CHAP A1 - Kerpen, N. A1 - Verworn, F. A1 - Bung, Daniel Bernhard A1 - Daemrich, K.-F. A1 - Schlurmann, Torsten T1 - Ermittlung von Wellenüberlaufmengen an Sturmflutschutzwänden auf Deichen T2 - Maritimer Wasserbau und Küsteningenieurwesen : 8. FZK-Kolloquium : Hannover 10. März, 2011 Y1 - 2011 SN - 1610-5249 SP - 63 EP - 68 ER - TY - CHAP A1 - Kirchhof, Michael A1 - Kraft, Bodo T1 - Dogmatisches „Entweder agil oder klassisch" im Projektmanagement hat ausgedient - die richtige Mischung macht's T2 - Projekt-Sternstunden : strahlende Erfolge durch Kompetenz Y1 - 2011 SN - 978-3-924841-60-7 N1 - PM-Forum <28, 2011, Nürnberg> ; PM-Forum 2011, 28. Internationales Deutsches Projektmanagement-Forum ; Nürnberg, 25. - 26.10.2011 ; Tagungsband SP - 414 EP - 425 PB - GPM CY - Nürnberg ER - TY - JOUR A1 - Kirchner, Patrick A1 - Li, Bin A1 - Spelthahn, Heiko A1 - Henkel, Hartmut A1 - Schneider, Andreas A1 - Friedrich, Peter A1 - Kolstad, Jens A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Thin-film calorimetric H2O2 gas sensor for the validation of germicidal effectivity in aseptic filling processes JF - Sensors and Actuators B: Chemical. 154 (2011), H. 2 Y1 - 2011 SN - 1873-3077 N1 - EUROSENSORS XXIII SP - 257 EP - 263 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Kirchner, Patrick A1 - Oberländer, Jan A1 - Friedrich, Peter A1 - Berger, Jörg A1 - Suso, Henri-Pierre A1 - Kupyna, Andriy A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Optimisation and fabrication of a calorimetric gas sensor built up on a polyimide substrate for H2O2 monitoring JF - Physica status solidi (a) : applications and material science. 208 (2011), H. 6 Y1 - 2011 SN - 1862-6319 SP - 1235 EP - 1240 PB - Wiley CY - Weinheim ER - TY - CHAP A1 - Kirsch, Ansgar A1 - Mattle, Bruno T1 - Einflussfaktoren auf die Erddruckverteilung bei eingeschütteten Tunneln T2 - Baustatik Baupraxis : BB / Fachtagung Baustatik Baupraxis. Lehrstühle und Institute für Statik, TH Aachen, TU Berlin, U Bochum [u.a.] Y1 - 2011 SP - 1 EP - 8 ER - TY - JOUR A1 - Kirschner-Hermanns, Ruth A1 - Klementz, T. A1 - Haselhuhn, Angelika A1 - Jakse, Gerhard A1 - Heidenreich, A. A1 - Brehmer, Bernhard T1 - Drangsymptomatik nach onkologisch erfolgreicher Prostatakarzinomtherapie : prospektive Studie zum Einfluss von Therapiemodalität, Morbidität und epidemiologischen Faktoren auf die Lebensqualität JF - Der Urologe Y1 - 2011 SN - 1433-0563 VL - Vol. 50 IS - Iss. 11 SP - 1412 EP - 1419 PB - Springer CY - Berlin ER - TY - JOUR A1 - Kleefeld, Andreas A1 - Reißel, Martin T1 - The Levenberg–Marquardt method applied to a parameter estimation problem arising from electrical resistivity tomography JF - Applied Mathematics and Computation Y1 - 2011 SN - 0096-3003 VL - 217 IS - 9 SP - 4490 EP - 4501 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Klocke, Martina T1 - Projektmodul im Bachelorstudiengang Maschinenbau bzw. Mechatronik T2 - Hochschulrektorenkonferenz HRK nexus : Kompetenzorientiertes Prüfen in den Ingenieurwissenschaften und in der Informatik. Gemeinsame Tagung von 4ING und nexus. 29.3.2011 Bremen Y1 - 2011 SP - 1 EP - 25 ER - TY - CHAP A1 - Knobloch, V. A1 - Kowalski, Julia A1 - Bösiger, P. A1 - Kozerke, S. T1 - Probabilistic Streamline Estimation from Accelerated Fourier Velocity Encoded Measurements T2 - Proceedings of the 19th ISMRM International Society for Magnetic Resonance in Medicine Y1 - 2011 N1 - ISMRM 19th Annual Meeting & Exhibition in Montréal, Québec, Canada SP - 1215 EP - 1215 ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Baumann, Marcus A1 - Vilser, Walthard A1 - Lanzl, Ines M. T1 - Pulse wave velocity in retinal arteries of healthy volunteers JF - British Journal of Ophthalmology (eBJO) Y1 - 2011 SN - 1468-2079 VL - 95 IS - 11 SP - 675 EP - 679 PB - BMJ Publ. Group CY - London ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Lanzl, Ines M. T1 - Can vascular function be assessed by the interpretation of retinal vascular diameter changes? JF - Investigative Ophthalmology & Visual Science, IOVS. 52 (2011), H. 1 Y1 - 2011 SN - 0146-0404 SP - 635 EP - 636 PB - ARVO CY - Rockville, Md. ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Lanzl, Ines M. A1 - Schmidt-Trucksäss, A. A1 - Sitnikova, Diana A1 - Ali, Mohammad A1 - Blume, Katharina A1 - Halle, Martin A1 - Hansser, Henner T1 - Dynamic retinal vessel response to flicker in obesity: A methodological approach JF - Microvascular Research Y1 - 2011 SN - 0026-2862 VL - 81 IS - 1 SP - 123 EP - 128 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Kraff, Oliver A1 - Bitz, Andreas A1 - Breyer, Tobias A1 - Kruszona, Stefan A1 - Maderwald, Stefan A1 - Brote, Irina A1 - Gizewski, Elke R. A1 - Ladd, Mark E. A1 - Quick, Harald H. T1 - A transmit/receive radiofrequency array for imaging the carotid arteries at 7 Tesla: coil design and first in vivo results JF - Investigative Radiology N2 - Objective: To develop a transmit/receive radiofrequency (RF) array for magnetic resonance imaging (MRI) of the carotid arteries at 7 T. The prototype is characterized in numerical simulations and bench measurements, and the feasibility of plaque imaging at 7 T is demonstrated in first in vivo images. Materials and Methods: The RF phased array coil consists of 8 surface loop coils. To allow imaging of both sides of the neck, the RF array is divided into 2 coil clusters, each with 4 overlapping loop elements. For safety validation, numerical computations of the RF field distribution and the corresponding specific absorption rate were performed on the basis of a heterogeneous human body model. To validate the coil model, maps of the transmit B1+ field were compared between simulation and measurement. In vivo images of a healthy volunteer and a patient (ulcerating plaque and a 50% stenosis of the right internal carotid artery) were acquired using a 3-dimensional FLASH sequence with a high isotropic spatial resolution of 0.54 mm as well as using pulse-triggered proton density (PD)/T2-weighted turbo spin echo sequences. Results: Measurements of the S-parameters yielded a reflection and isolation of the coil elements of better than −18 and −13 dB, respectively. Measurements of the g-factor indicated good image quality for parallel imaging acceleration factors up to 2.4. A similar distribution and a very good match of the absolute values were found between the measured and simulated B1+ transmit RF field for the validation of the coil model. In vivo images revealed good signal excitation of both sides of the neck and a high vessel-to-background image contrast for the noncontrast-enhanced 3-dimensional FLASH sequence. Imaging at 7 T could depict the extent of stenosis, and revealed the disruption and ulcer of the plaque. Conclusions: This study demonstrates that 2 four-channel transmit/receive RF arrays for each side of the neck is a suitable concept for in vivo MRI of the carotid arteries at 7 Tesla. Further studies are needed to explore and exploit the full potential of 7 T high-field MRI for carotid atherosclerotic plaque imaging. Y1 - 2011 U6 - https://doi.org/10.1097/RLI.0b013e318206cee4 SN - 1536-0210 VL - 46 IS - 4 SP - 246 EP - 254 PB - Wolters Kluwer CY - Köln ER - TY - CHAP A1 - Kroll-Ludwigs, Kathrin T1 - Einleitung vor § 1297 BGB T2 - Erman Bürgerliches Gesetzbuch : Handkommentar mit AGBG, EGBGB, ErbbauVO, HausratsVO, HausTWG, ProdHaftG, Sachen-RBerG, SchuldRAnpG, VerbrKrG. Bd. 2 Bd. 2 [§§ 759 - 2385, ProdHaftG, ErbbauRG, VersAus-glG, VBVG, LPartG, WEG, EGBGB] Y1 - 2011 SN - 9783504471019 SP - 4299 PB - Verlag Dr. Otto Schmidt CY - Köln ET - 13., neu bearb. Aufl. ER - TY - CHAP A1 - Kroll-Ludwigs, Kathrin T1 - Vor § 1297 bis § 1302 BGB (Verlöbnis) T2 - Erman Bürgerliches Gesetzbuch : Handkommentar mit AGBG, EGBGB, ErbbauVO, HausratsVO, HausTWG, ProdHaftG, Sachen-RBerG, SchuldRAnpG, VerbrKrG. Bd. 2 Bd. 2 [§§ 759 - 2385, ProdHaftG, ErbbauRG, VersAus-glG, VBVG, LPartG, WEG, EGBGB] Y1 - 2011 SN - 9783504471019 PB - Verlag Dr. Otto Schmidt CY - Köln ET - 13., neu bearb. Aufl. ER - TY - CHAP A1 - Kroll-Ludwigs, Kathrin T1 - Vor § 1353 bis § 1362 BGB (Allgemeine Ehewirkungen) T2 - Erman Bürgerliches Gesetzbuch : Handkommentar mit AGBG, EGBGB, ErbbauVO, HausratsVO, HausTWG, ProdHaftG, Sachen-RBerG, SchuldRAnpG, VerbrKrG. Bd. 2 Bd. 2 [§§ 759 - 2385, ProdHaftG, ErbbauRG, VersAus-glG, VBVG, LPartG, WEG, EGBGB] Y1 - 2011 SN - 9783504471019 PB - Verlag Dr. Otto Schmidt CY - Köln ET - 13., neu bearb. Aufl. ER - TY - JOUR A1 - Kroll-Ludwigs, Kathrin T1 - Anmerkung zu EuGH, Urt. v. 1.3.2011, Rs. C-236/09 Association belge des Consomma-teurs Test-Achats JF - JuristenZeitung (JZ) Y1 - 2011 U6 - https://doi.org/10.1628/002268811796448996 SN - 1868-7067 VL - 66 IS - 14 SP - 734 EP - 737 PB - Mohr Siebeck CY - Tübingen ER - TY - JOUR A1 - Kroll-Ludwigs, Kathrin T1 - Anmerkung zu EuGH, Urt. v. 22. 12. 2010, Rs. C-208/09 - Sayn-Wittgenstein JF - GPR : Zeitschrift für das Privatrecht der Europäischen Union Y1 - 2011 U6 - https://doi.org/10.1515/gpr.2011.8.5.242 SN - 2193-9519 IS - 5 SP - 242 EP - 245 PB - Verlag Dr. Otto Schmidt CY - Köln ER - TY - JOUR A1 - Krott, Daniel A1 - Gerhards, Michael A1 - Skorupa, Sascha A1 - Sander, Volker T1 - NHiLA - Bridging the Gap Between .NET and UNICORE JF - UNICORE Summit 2011 : proceedings, 7-8 July 2011, Torun, Poland / Mathilde Romberg ... (Eds.) Y1 - 2011 SN - 9783893367504 N1 - UNICORE Summit ; (2011 ; 2011.07.07-08 ; Torun) ; Schriften des Forschungszentrums Jülich IAS Series 9 SP - 77 EP - 86 PB - Forschungszentrum Jülich CY - Jülich ER - TY - JOUR A1 - Kuperjans, Isabel T1 - Gute Planung ist alles : Energieeffizienz in der Pharmaproduktion JF - Pharma + Food Y1 - 2011 SN - 1434-8942 VL - 2011 IS - 2 SP - 8 EP - 10 PB - Hüthig CY - Heidelberg ER - TY - JOUR A1 - Kurulgan Demirci, Eylem A1 - Demirci, T. A1 - Trzewik, Jürgen A1 - Linder, Peter A1 - Karakulah, G. A1 - Artmann, Gerhard A1 - Sakizli, M. A1 - Temiz Artmann, Aysegül T1 - Genome-Wide Gene Expression Analysis of NIH 3T3 Cell Line Under Mechanical Stimulation JF - Cellular and molecular bioengineering. 4 (2011), H. 1 Y1 - 2011 SN - 1865-5025 SP - 46 EP - 55 PB - Springer CY - Berlin ER - TY - CHAP A1 - Kurz, Melanie A1 - Zebner, Frank ED - Eisele, Petra ED - Bürdek, Bernhard E. T1 - Zum Verhältnis von Design und Technik T2 - Design, Anfang des 21 Jh. : Diskurse und Perspektiven Y1 - 2011 SN - 978-3-89986-150-1 SP - 174 EP - 185 PB - avedition CY - Ludwigsburg ER - TY - CHAP A1 - Küppers, Christine A1 - Groebel, Simone A1 - Kuperjans, Isabel A1 - Dielmann, Klaus-Peter T1 - Molekulargenetische Analysen zur Optimierung der Biogasgewinnung T2 - Biogas 2011 : 4. Innovationskongress ; Effizienzsteigerung von Biogasanlagen ; Vorstellung der 17 besten Biogas-Innovationen der letzten 12 Monate ; 12. - 13. Mai 2011, im ZUK der Deutschen Bundesstiftung Umwelt ; Tagungsband Y1 - 2011 SN - 978-3-9813776-1-3 SP - 45 EP - 48 PB - Profair Consult+Project CY - Hildesheim ER - TY - BOOK A1 - Laack, Walter van T1 - Wer stirbt, ist nicht tot! 2. Aufl. Y1 - 2011 SN - 978-3-936624-13-7 N1 - auch als Taschenbuch ISBN 978-3-936624-12-0 PB - van Laack CY - Aachen ER - TY - JOUR A1 - Landers, Ernst Ulrich A1 - Kern, Alexander T1 - Future evolution of risk management for structures : Advancement for the future IEC 62305-2 Ed3 Y1 - 2011 N1 - XI International Symposium on Lightning Protection (SIPDA), Fortaleza (Brasilien), 2011. SP - 1 EP - 6 PB - IEEE CY - New York ER - TY - JOUR A1 - Lanzl, Ines M. A1 - Seidova, Seid-Fatima A1 - Maier, Mathias A1 - Schmidt-Trucksäss, Arno A1 - Halle, Martin A1 - Kotliar, Konstantin T1 - Dynamic retinal vessel response to flicker in age-related macular degeneration patients before and after vascular endothelial growth factor inhibitor injection JF - Acta Ophthalmologica Y1 - 2011 SN - 1755-3768 VL - 89 IS - 5 SP - 472 EP - 479 PB - Wiley CY - Weinheim ER - TY - CHAP A1 - Lao, B. A1 - Bührig-Polaczek, A. A1 - Röth, Thilo ED - Wielage, Bernhard T1 - Funktionsintegrierte Leichtbaustrukturen in gussintensiver Metall-Hybridbauweise T2 - Verbundwerkstoffe und Werkstoffverbunde: Tagungsband zum 18. Symposium ; 30.03.2011 bis 01.04.2011, Chemnitz Y1 - 2011 SN - 978-3-00-033801-4 N1 - Schriftenreihe Werkstoffe und werkstofftechnische Anwendungen ; 41 SP - 413 EP - 421 PB - Eigenverlag CY - Chemnitz ER - TY - JOUR A1 - Levers, A. A1 - Staat, Manfred A1 - Laack, Walter van T1 - Analyse der Langzeitwirkung der MBST® KernspinResonanzTherapie bei Gonarthrose T1 - Analysis of the Long-term Effect of the MBST® Nuclear Magnetic Resonance Therapy on Gonarthrosis N2 - Originalausgabe: Orthopädische Praxis Jg. 47. 2011 H. 11; S. 536-543. Mit freundlicher Genehmigung des Verlags Zusammenfassung: Auf der Basis von Patientenabfragen mittels Fragebogen zum Schmerzempfinden und zur Einschränkung bei Aktivitäten des alltäglichen Lebens wird die Langzeitwirkung der MBST® KernspinResonanz-Therapie bei Gonarthrose untersucht. An der Studie nahmen 39 Patienten teil, bei denen die Therapie bis zu vier Jahre zurückliegt. Neben einer Gesamtbetrachtung wird der Erfolg auch in Abhängigkeit von Alter, Geschlecht und sportlicher Aktivität analysiert. Insgesamt weist die Studie auf eine anhaltende Verbesserung des Gesundheitszustands mit zum Teil deutlicher Schmerzlinderung auch noch nach vier Jahren hin, jedoch mit einer leichten Schmerzzunahme gegen Ende des Untersuchungszeitraums von vier Jahren. Eine tendenziell positivere Wirkung bei Frauen, älteren Menschen oder auch sportlich nicht-aktiven Patienten lässt auf eine mögliche Beeinflussung des Erfolgs der Therapie durch (Über-)Belastung im Alltag schließen. Ein zusätzlich positiver Effekt der Therapie auf die Knochendichte ist ebenfalls denkbar, dies bleibt jedoch offen. N2 - Original edition: Orthopädische Praxis Vol. 47. 2011 Issue 11; P. 536-543. On the friendly authority of the publisher. Abstract: Based upon a questionnaire for patient-queries regarding pain-sensation and activity-restrictions during everyday task, the long-term effect of MBST® nuclear magnetic resonance therapy is studied in osteoarthritis of the knee. 39 patients, whose therapy dates back up to four years, participated in the study. In addition to an overall view, the success of this therapy is also analyzed regarding age, gender and physical activities. Overall, the study pointed out a sustained improvement in the patients´ local health-status with a significant pain-relief even after four years, but also with a slight increase in pain towards the end of that four-year period. There tends to be more positive effect on women, on elderly of also on even non-sports-active patients which suggest a possible influence by daily (over)-stressing on the success of the therapy. An additional positive effect of the therapy on bone density is also conceivable, however, this remains open. KW - Kniegelenkarthrose KW - Gonarthrose KW - MBST KW - Arthosetherapie KW - gonarthrosis KW - MBST KW - arthrosis therapy Y1 - 2011 ER - TY - CHAP A1 - Lind, Thorsten Patric T1 - Wirkungen der Eröffnung des Insolvenzverfahrens : §§ 129, 132, 133, 144, 145 T2 - Bankenkommentar zum Insolvenzrecht Y1 - 2011 SN - 978-3-940976-55-0 SP - 1145 EP - 1585 PB - Finanz Colloquium CY - Heidelberg ER - TY - JOUR A1 - Lind, Thorsten Patric T1 - Handelndenhaftung bei Vorrats- oder Mantel-GmbH nur für vor Offenlegung der wirtschaftlichen Neugründung ohne Zustimmung aller Gesellschafter vorgenommene Geschäfte : BGH, Urteil vom 12.07.2011 - II ZR 71/11 : Anmerkung JF - Fachdienst Zivilrecht - LMK - Kommentierte BGH-Rechtsprechung, Lindenmaier-Möhring Y1 - 2011 SN - 1611-1095 IS - 11 PB - Beck CY - München ER - TY - JOUR A1 - Lind, Thorsten Patric T1 - Keine Beseitigung der Zahlungsunfähigkeit und ihrer Kenntnis durch Patronatserklärung : BGH, Urteil vom 19.05.2011 - IX ZR 9/10 : Anmerkung JF - Fachdienst Zivilrecht - LMK - Kommentierte BGH-Rechtsprechung, Lindenmaier-Möhring Y1 - 2011 SN - 1611-1095 IS - Ausg. 8 SP - 320922 PB - Beck CY - München ER - TY - CHAP A1 - Loeb, Horst W. A1 - Schartner, Karl-Heinz A1 - Dachwald, Bernd A1 - Ohndorf, Andreas A1 - Seboldt, Wolfgang T1 - An Interstellar – Heliopause mission using a combination of solar/radioisotope electric propulsion T2 - Presented at the 32nd International Electric Propulsion Conference N2 - There is common agreement within the scientific community that in order to understand our local galactic environment it will be necessary to send a spacecraft into the region beyond the solar wind termination shock. Considering distances of 200 AU for a new mission, one needs a spacecraft travelling at a speed of close to 10 AU/yr in order to keep the mission duration in the range of less than 25 yrs, a transfer time postulated by ESA.Two propulsion options for the mission have been proposed and discussed so far: the solar sail propulsion and the ballistic/radioisotope electric propulsion. As a further alternative, we here investigate a combination of solar-electric propulsion and radioisotope-electric propulsion. The solar-electric propulsion stage consists of six 22 cm diameter “RIT-22”ion thrusters working with a high specific impulse of 7377 s corresponding to a positive grid voltage of 5 kV. Solar power of 53 kW BOM is provided by a light-weight solar array. The REP-stage consists of four space-proven 10 cm diameter “RIT-10” ion thrusters that will be operating one after the other for 9 yrs in total. Four advanced radioisotope generators provide 648 W at BOM. The scientific instrument package is oriented at earlier studies. For its mass and electric power requirement 35 kg and 35 W are assessed, respectively. Optimized trajectory calculations, treated in a separate contribution, are based on our “InTrance” method.The program yields a burn out of the REP stage in a distance of 79.6 AU for a usage of 154 kg of Xe propellant. With a C3 = 45,1 (km/s)2 a heliocentric probe velocity of 10 AU/yr is reached at this distance, provided a close Jupiter gravity assist adds a velocity increment of 2.7 AU/yr. A transfer time of 23.8 yrs results for this scenario requiring about 450 kg Xe for the SEP stage, jettisoned at 3 AU. We interpret the SEP/REP propulsion as a competing alternative to solar sail and ballistic/REP propulsion. Omiting a Jupiter fly-by even allows more launch flexibility, leaving the mission duration in the range of the ESA specification. Y1 - 2011 N1 - 32nd International Electric Propulsion Conference, 11-15 September. Wiesbaden, Germany SP - 1 EP - 7 ER - TY - JOUR A1 - Lustfeld, H. A1 - Hirschfeld, J. A. A1 - Reißel, Martin A1 - Steffen, B. T1 - Enhancement of precision and reduction of measuring points in tomographic reconstructions JF - Physics Letters A Y1 - 2011 SN - 0375-9601 VL - 375 IS - 8 SP - 1167 EP - 1171 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Maier, M. M. A1 - Feucht, N. A1 - Winkler von Mohrenfels, C. A1 - Kotliar, Konstantin A1 - Fabian, E. A1 - Lohmann, C. P. T1 - Nahtlose Cerclage mit Skleratunnelfixation. Sutureless Encircling Band - Clinical Experience JF - Klinische Monatsblätter für Augenheilkunde Y1 - 2011 SN - 0344-6360 VL - 228 IS - 5 SP - 473 EP - 476 PB - Thieme CY - Stuttgart ER - TY - JOUR A1 - Malzahn, Kerstin A1 - Windmiller, Joshua Ray A1 - Valdés-Ramírez, Gabriela A1 - Wang, Joseph A1 - Schöning, Michael Josef T1 - Wearable electrochemical sensors for in situ analysis in marine environments JF - Analyst. 136 (2011), H. 14 Y1 - 2011 SN - 0003-2654 SP - 2912 EP - 2917 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Manea, Marilena A1 - Leurs, Ulrike A1 - Orban, Erika A1 - Baranyai, Zsuzsa A1 - Öhlschläger, Peter A1 - Marquardt, Andreas A1 - Schulcz, Akos A1 - Tejeda, Miguel T1 - Enhanced Enzymatic Stability and Antitumor Activity of Daunorubicin-GnRH-III Bioconjugates Modified in Position 4 JF - Bioconjugate Chemistry Y1 - 2011 SN - 1520-4812 VL - 22 IS - 7 SP - 1320 EP - 1329 PB - ACS CY - Washington, DC ER - TY - JOUR A1 - Martin, Conrad A1 - Frauenrath, Tobias A1 - Özerdem, Celal A1 - Renz, Wolfgang A1 - Niendorf, Thoralf T1 - Development and evaluation of a small and mobile Magneto Alert Sensor (MALSE) to support safety requirements for magnetic resonance imaging JF - European Radiology N2 - Objective The purpose of this study is to (i) design a small and mobile Magnetic field ALert SEnsor (MALSE), (ii) to carefully evaluate its sensors to their consistency of activation/deactivation and sensitivity to magnetic fields, and (iii) to demonstrate the applicability of MALSE in 1.5 T, 3.0 T and 7.0 T MR fringe field environments. Methods MALSE comprises a set of reed sensors, which activate in response to their exposure to a magnetic field. The activation/deactivation of reed sensors was examined by moving them in/out of the fringe field generated by 7TMR. Results The consistency with which individual reed sensors would activate at the same field strength was found to be 100% for the setup used. All of the reed switches investigated required a substantial drop in ambient magnetic field strength before they deactivated. Conclusions MALSE is a simple concept for alerting MRI staff to a ferromagnetic object being brought into fringe magnetic fields which exceeds MALSEs activation magnetic field. MALSE can easily be attached to ferromagnetic objects within the vicinity of a scanner, thus creating a barrier for hazardous situations induced by ferromagnetic parts which should not enter the vicinity of an MR-system to occur. KW - MRI KW - MR safety KW - Magneto alert sensor KW - High field MRI KW - Uktrahigh field MRI Y1 - 2011 U6 - https://doi.org/10.1007/s00330-011-2153-z SN - 1432-1084 VL - 21 SP - 2187 EP - 2192 PB - Springer CY - Berlin, Heidelberg ER - TY - GEN A1 - Martin, Conrad Steven A1 - Frauenrath, Tobias A1 - Zerdem, Celal A1 - Renz, Wolfgang A1 - Niendorf, Thoralf T1 - Evaluation of Magneto Alert Sensor (MALSE) to Improve MR Safety by Decreasing the Incidence of Ferromagnetic Projectile Accidents T2 - 2011 ISMRM Annual Meeting Proceedings N2 - The magnetic forces of fringe magnetic fields of MR systems on ferromagnetic components can impose a severe patient, occupational health and safety hazard. MRI accidents are listed as number 9 of the top 10 risks in modern medicine. With the advent of ultrahigh field MR systems including passively shielded magnet versions, this risk, commonly known as the missile or projectile effect is even more pronounced. A strategy employing magnetic field sensors which can be attached to ferromagnetic objects that are commonly used in a clinical environment is conceptually appealing for the pursuit of reducing the risk of ferromagnetic projectile accidents. Y1 - 2011 SN - 1545-4428 N1 - ISMRM 19th Annual Meeting & Exhibition, 7-13 May 2011, Montreal, Quebec, Canada ER - TY - JOUR A1 - Martins, Berta M. A1 - Blaser, Martin A1 - Feliks, Mikolaj A1 - Ullmann, Matthias G. A1 - Buckel, Wolfgang A1 - Selmer, Thorsten T1 - Structural basis for a Kolbe-type decarboxylation catalyzed by a glycyl radical enzyme JF - Journal of the American Chemical Society Y1 - 2011 N1 - Just accepted manuscript SP - 1 EP - 33 PB - ACS Publications CY - Washington, DC ER - TY - CHAP A1 - Matcha, Heike A1 - Barczik, Günter ED - Valena, Tomas ED - Avermaete, Tom ED - Vrachliotis, Georg T1 - Mass Diversity: Individualized housing via parametric typology T2 - Structuralism Reloaded? Rule-Based Design in Architecture and Urbanism Y1 - 2011 SN - 978-3-936681-47-5 SP - 354 EP - 358 PB - Edition Axel Menges CY - Fellbach ER - TY - JOUR A1 - Maus, Stefan A1 - Höfken, Hans-Wilhelm A1 - Schuba, Marko T1 - Forensic Analysis of Geodata in Android Smartphones Y1 - 2011 N1 - Cyberforensics 2011, Glasgow SP - 1 EP - 11 ER - TY - JOUR A1 - Mayer, Claudia T1 - Das globale Dorf ist sein bekanntes Schlagwort JF - Aachener Nachrichten KW - McLuhan, Marshall Y1 - 2011 N1 - zugleich Aachener Zeitung vom 27.12.2011 Seite 12 IS - 27.12.2011 SP - 12 EP - 12 ER - TY - BOOK A1 - Meskouris, Konstantin A1 - Hinzen, Klaus-Günter A1 - Butenweg, Christoph A1 - Mistler, Michael T1 - Bauwerke und Erdbeben : Grundlagen - Anwendung - Beispiele. - 3., aktualisierte und erweiterte Auflage Y1 - 2011 SN - 978-3-8348-9856-2 (E-Book) ; 978-3-8348-0779-3 (Print) U6 - https://doi.org/10.1007/978-3-8348-9856-2 PB - Vieweg + Teubner CY - Wiesbaden ET - 3., aktualisierte und erweiterte Auflage ER -