TY - JOUR A1 - Albanna, Walid A1 - Lueke, Jan Niklas A1 - Sjapic, Volha A1 - Kotliar, Konstantin A1 - Hescheler, Jürgen A1 - Clusmann, Hans A1 - Sjapic, Sergej A1 - Alpdogan, Serdan A1 - Schneider, Toni A1 - Schubert, Gerrit Alexander A1 - Neumaier, Felix T1 - Electroretinographic Assessment of Inner Retinal Signaling in the Isolated and Superfused Murine Retina JF - Current Eye Research Y1 - 2017 U6 - https://doi.org/10.1080/02713683.2017.1339807 SN - 1460-2202 IS - Article in press SP - 1 EP - 9 PB - Taylor & Francis CY - London ER - TY - JOUR A1 - Honarvarfard, Elham A1 - Gamella, Maria A1 - Channaveerappa, Devika A1 - Darie, Costel C. A1 - Poghossian, Arshak A1 - Schöning, Michael Josef A1 - Katz, Evgeny T1 - Electrochemically Stimulated Insulin Release from a Modified Graphene–functionalized Carbon Fiber Electrode JF - Electroanalysis N2 - A graphene-functionalized carbon fiber electrode was modified with adsorbed polyethylenimine to introduce amino functionalities and then with trigonelline and 4-carboxyphenylboronic acid covalently bound to the amino groups. The trigonelline species containing quarterized pyridine groups produced positive charge on the electrode surface regardless of the pH value, while the phenylboronic acid species were neutral below pH 8 and negatively charged above pH 9 (note that their pKa=8.4). The total charge on the monolayer-modified electrode was positive at the neutral pH and negative at pH > 9. Note that 4-carboxyphenylboronic acid was attached to the electrode surface in molar excess to trigonelline, thus allowing the negative charge to dominate on the electrode surface at basic pH. Negatively charged fluorescent dye-labeled insulin (insulin-FITC) was loaded on the modified electrode surface at pH 7.0 due to its electrostatic attraction to the positively charged interface. The local pH in close vicinity to the electrode surface was increased to ca. 9–10 due to consumption of H+ ions upon electrochemical reduction of oxygen proceeding at the potential of −1.0 V (vs. Ag/AgCl) applied on the modified electrode. The process resulted in recharging of the electrode surface to the negative value due to the formation of the negative charge on the phenylboronic acid groups, thus resulting in the electrostatic repulsion of insulin-FITC and stimulating its release from the electrode surface. The insulin release was characterized by fluorescence spectroscopy (using the FITC-labeled insulin), by electrochemical measurements on an iridium oxide, IrOx, electrode and by mass spectrometry. The graphene-functionalized carbon fiber electrode demonstrated significant advantages in the signal-stimulated insulin release comparing with the carbon fiber electrode without the graphene species. Y1 - 2017 U6 - https://doi.org/10.1002/elan.201700095 SN - 1521-4109 VL - 29 IS - 6 SP - 1543 EP - 1553 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Pfaff, Raphael T1 - Einsatz von offenen Onlinekursen in der Eisenbahnlehre JF - Deine Bahn N2 - Eigene positive Erfahrungen mit Onlinekursen sowie die geringen Studierendenzahlen in der Präsenzlehre gaben den Anstoß zu einem Experiment mit einem offenen Onlinekurs auf der Plattform Udemy. Die Erfahrungen sowohl bei der Erstellung und als auch im Lehrbetrieb waren positiv und führten zu einer neuen Beschäftigung mit Inhalten und Lernenden, getrieben durch die Anforderungen der Lernplattform. Y1 - 2017 SN - 0948-7263 IS - 1 SP - 12 EP - 16 PB - Bahn-Fachverlag CY - Berlin ER - TY - JOUR A1 - Peterson, Leif Arne A1 - Röth, Thilo A1 - Uibel, Thomas T1 - Einsatz von Holzwerkstoffen in Fahrzeugstrukturen JF - Bauen mit Holz Y1 - 2017 SN - 0005-6545 N1 - gedruckt in der Bereichsbibliothek Bayernallee IS - 3 SP - 32 EP - 38 PB - Bruderverlag CY - Köln ER - TY - CHAP A1 - Kroll-Ludwigs, Kathrin ED - Erman, Walter ED - Grunewald, Barbara ED - Maier-Reimer, Georg T1 - Einleitung vor § 1297 T2 - Bürgerliches Gesetzbuch : Handkommentar mit AGG, EGBGB (Auszug), ErbbauRG, HausratsVO, LPartG, ProdHaftG, UKlaG, VAHRG und WEG Y1 - 2018 SN - 978-3-504-47103-3 SP - 4415 EP - 4422 PB - Verlag Dr. Otto Schmidt CY - Köln ET - 15., neu bearbeitete Auflage ER - TY - JOUR A1 - Czupalla, Markus T1 - Ein Garten im Weltraum JF - Spektrum der Wissenschaft Y1 - 2017 PB - Spektrum-der-Wiss.-Verl.-Ges. CY - Heidelberg ER - TY - CHAP A1 - Schlemmer, Katharina A1 - Porst, Dariusz A1 - Bassam, Rasha A1 - Artmann, Gerhard A1 - Digel, Ilya ED - Erni, Daniel ED - Fischerauer, Alice ED - Himmel, Jörg ED - Seeger, Thomas ED - Thelen, Klaus T1 - Effects of nitric oxide (NO) and ATP on red blood cell phenotype and deformability T2 - 2nd YRA MedTech Symposium 2017 : June 8th - 9th / 2017 / Hochschule Ruhr-West Y1 - 2017 SN - 978-3-9814801-9-1 U6 - https://doi.org/10.17185/duepublico/43984 N1 - A young researchers track of the 7th IEEE Workshop & SENSORICA 2017 SP - 100 EP - 101 PB - Universität Duisburg-Essen CY - Duisburg ER - TY - JOUR A1 - Arreola, Julio A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Effect of O2 plasma on properties of electrolyte-insulator-semiconductor structures JF - physica status solidi a : applications and materials sciences N2 - Prior to immobilization of biomolecules or cells onto biosensor surfaces, the surface must be physically or chemically activated for further functionalization. Organosilanes are a versatile option as they facilitate the immobilization through their terminal groups and also display self-assembly. Incorporating hydroxyl groups is one of the important methods for primary immobilization. This can be done, for example, with oxygen plasma treatment. However, this treatment can affect the performance of the biosensors and this effect is not quite well understood for surface functionalization. In this work, the effect of O2 plasma treatment on EIS sensors was investigated by means of electrochemical characterizations: capacitance–voltage (C–V) and constant capacitance (ConCap) measurements. After O2 plasma treatment, the potential of the EIS sensor dramatically shifts to a more negative value. This was successfully reset by using an annealing process. KW - surface functionalization KW - O2 plasma KW - hydroxylation KW - electrolyte-insulator semiconductor sensor (EIS) KW - annealing Y1 - 2017 U6 - https://doi.org/10.1002/pssa.201700025 SN - 1862-6319 VL - 214 PB - Wiley-VCH CY - Weinheim ER - TY - CHAP A1 - Thurn, Laura A1 - Balc, Nicolae A1 - Gebhardt, Andreas A1 - Kessler, Julia T1 - Education packed in technology to promote innovations: Teaching Additive Manufacturing based on a rolling Lab T2 - Modern Technologies in Manufacturing (MTeM 2017 - AMaTUC) Y1 - 2017 U6 - https://doi.org/10.1051/matecconf/201713702013 SN - 2261-236X N1 - MATEC Web Conf. Volume 137, 2017 Matec Web of Conferences., 137(2017)02013 ER - TY - JOUR A1 - Wollert, Jörg T1 - Echtzeit-Ethernet - Basis für Industrie 4.0 JF - Design & Elektronik Y1 - 2017 SN - 0933-8667 N1 - Echtzeit für Industrie 4.0. - Teil 1 IS - 12 SP - 38 EP - 41 PB - WEKA-Fachmedien CY - Haar, München ER -