TY  - CHAP
A1  - Baronas, Romas
A1  - Ivanauskas, Feliksas
A1  - Kulys, Juozas
T1  - Mathematical modeling of biosensors based on an array of enzyme microreactors
N2  - This paper presents a two-dimensional-in-space mathematical model of biosensors based on an array of enzyme microreactors immobilised on a single electrode. The modeling system acts under amperometric conditions. The microreactors were modeled by particles and by strips. The model is based on the diffusion equations containing a nonlinear term related to the Michaelis-Menten kinetics of the enzymatic reaction. The model involves three regions: an array of enzyme microreactors where enzyme reaction as well as mass transport by diffusion takes place, a diffusion limiting region where only the diffusion takes place, and a convective region, where the analyte concentration is maintained constant. Using computer simulation, the influence of the geometry of the microreactors and of the diffusion region on the biosensor response was investigated. The digital simulation was carried out using the finite difference technique.
KW  - Biosensor
KW  - Reaction-diffusion
KW  - modeling biosensor
KW  - microreactor
Y1  - 2006
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:a96-opus-1569
ER  - 
TY  - CHAP
A1  - Barek, Jiri
A1  - Fischer, Jan
A1  - Navratil, Tomas
A1  - Peckova, Karolina
A1  - Yosypchuk, Bogdan
T1  - Silver solid amalgam electrodes as sensors for chemical carcinogens
N2  - The applicability of differential pulse voltammetry (DPV) and adsorptive stripping voltammetry (AdSV) at a non-toxic meniscus-modified silver solid amalgam electrode (m-AgSAE) for the determination of trace amounts of genotoxic substances was demonstrated on the determination of micromolar and submicromolar concentrations of 3-nitrofluoranthene using methanol - 0.01 mol L-1 NaOH (9:1) mixture as a base electrolyte and of Ostazine Orange using 0.01 mol L-1 NaOH as a base electrolyte.
KW  - Biosensor
KW  - Solid amalgam electrodes
KW  - voltammetry
KW  - carcinogens
KW  - 3-nitrofluoranthene
KW  - Ostazine Orange
Y1  - 2006
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:a96-opus-1554
ER  - 
TY  - CHAP
A1  - Arida, Hassan A.
A1  - Kloock, Joachim P.
A1  - Schöning, Michael Josef
T1  - Novel organic membrane-based thin-film microsensors for the determination of heavy metal cations
N2  - A first step towards the fabrication and electrochemical evaluation of thin-film microsensors based on organic PVC membranes for the determination of Hg(II), Cd(II), Pb(II) and Cu(II) ions in solutions has been realised. The membrane-coating mixture used in the preparation of this new type of microsensors is incorporating PVC as supporting matrix, o-nitrophenyloctylether (o-NPOE) as solvent mediator and a recently synthesized Hg[dimethylglyoxime(phene)]2+ and Bis-(4-hydroxyacetophenone)-ethylenediamine as electroactive materials for Hg(II) and Cd(II), respectively. A set of three commercialised ionophores for Cd(II), Pb(II) and Cu(II) has been also used for comparison. Thin-film microsensors based on these membranes showed a Nernstian response of slope (26-30 mV/dec.) for the respective tested cations. The potentiometric response characteristics (linear range, pH range, detection limit and response time) are comparable with those obtained by conventional membranes as well as coated wire electrodes prepared from the same membrane. The realisation of the new organic membrane-based thin-film microsensors overcomes the problem of an insufficient selectivity of solid-state-based thinfilm sensors.
KW  - Biosensor
KW  - Heavy metal detection
KW  - thin-film microsensors
KW  - organic PVC membranes
Y1  - 2006
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:a96-opus-1545
ER  -